LEPOC|Ensembl=ENSLOCG00000008751.1|UniProtKB=W5MQK7 W5MQK7 PTHR45817:SF6 LYSYL OXIDASE-LIKE-RELATED PROTEIN-LYSINE 6-OXIDASE catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;extracellular structure organization#GO:0043062;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;extracellular matrix organization#GO:0030198;enzyme-linked receptor protein signaling pathway#GO:0007167;collagen fibril organization#GO:0030199;cell communication#GO:0007154;external encapsulating structure organization#GO:0045229;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000013295.1|UniProtKB=W5N6X8 W5N6X8 PTHR21646:SF20 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 43 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000012532.1|UniProtKB=W5N474 W5N474 PTHR19143:SF422 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000009334.1|UniProtKB=W5MSN2 W5MSN2 PTHR11960:SF29 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E FAMILY MEMBER 1C ISOFORM X1 binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000015319.1|UniProtKB=W5NDZ1 W5NDZ1 PTHR31077:SF1 U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN U4_U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000015015.1|UniProtKB=W5NCX6 W5NCX6 PTHR24340:SF38 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-3.1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007378.1|UniProtKB=W5MKN7 W5MKN7 PTHR46810:SF1 INACTIVE POLYGLYCYLASE TTLL10 INACTIVE POLYGLYCYLASE TTLL10 catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;ligase activity, forming carbon-nitrogen bonds#GO:0016879 LEPOC|Ensembl=ENSLOCG00000000102.1|UniProtKB=W5LVF5 W5LVF5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011844.1|UniProtKB=W5N1Q6 W5N1Q6 PTHR13382:SF10 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B ATP SYNTHASE SUBUNIT S, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000011028.1|UniProtKB=W5MYS6 W5MYS6 PTHR11213:SF1 GLUCAGON-FAMILY NEUROPEPTIDE PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;neuropeptide hormone activity#GO:0005184;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of MAPK cascade#GO:0043408;neuron differentiation#GO:0030182;regulation of localization#GO:0032879;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of protein localization#GO:0032880;neuron development#GO:0048666;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;neuropeptide signaling pathway#GO:0007218;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856 perikaryon#GO:0043204;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005 neuropeptide#PC00162 Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#G06667;Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#P06800;Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#G06879 LEPOC|Ensembl=ENSLOCG00000017853.1|UniProtKB=W5NMU7 W5NMU7 PTHR11929:SF10 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE 9 glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000002532.1|UniProtKB=W5M3L1 W5M3L1 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007339.1|UniProtKB=W5MKI2 W5MKI2 PTHR11266:SF39 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cell communication#GO:0010646;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological quality#GO:0065008;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;negative regulation of signal transduction#GO:0009968;regulation of membrane permeability#GO:0090559;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of localization#GO:0032879;regulation of transport#GO:0051049 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017046.1|UniProtKB=W5NKA6 W5NKA6 PTHR10374:SF30 LACTOYLGLUTATHIONE LYASE GLYOXALASE I LACTOYLGLUTATHIONE LYASE lyase#PC00144;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016943.1|UniProtKB=W5NJY5 W5NJY5 PTHR24203:SF95 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 6 ISOFORM X1-RELATED regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;establishment or maintenance of cell polarity#GO:0007163;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;cellular process#GO:0009987;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000015082.1|UniProtKB=W5ND58 W5ND58 PTHR42884:SF35 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN-LIKE PROTEASE 2 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;proteolysis#GO:0006508;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;hormone metabolic process#GO:0042445;cellular process#GO:0009987;peptide hormone processing#GO:0016486;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Endothelin signaling pathway#P00019>furin#P00575;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 LEPOC|Ensembl=ENSLOCG00000005584.1|UniProtKB=W5MED2 W5MED2 PTHR12207:SF27 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2B cellular anatomical structure#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007866.1|UniProtKB=W5MMF7 W5MMF7 PTHR24251:SF31 OVOCHYMASE-RELATED PROCOLLAGEN C-ENDOPEPTIDASE ENHANCER 2 peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;peptidase regulator activity#GO:0061134;binding#GO:0005488;collagen binding#GO:0005518;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017381.1|UniProtKB=W5NLH7 W5NLH7 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002641.1|UniProtKB=W5M3Z8 W5M3Z8 PTHR10887:SF341 DNA2/NAM7 HELICASE FAMILY NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000000981.1|UniProtKB=W5LYC1 W5LYC1 PTHR46881:SF1 PALMDELPHIN PALMDELPHIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011389.1|UniProtKB=W5N040 W5N040 PTHR14319:SF6 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 TRANSMEMBRANE PROTEIN 8B cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002860.1|UniProtKB=W5M4Q8 W5M4Q8 PTHR23288:SF6 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;regulation of DNA-templated transcription elongation#GO:0032784;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;snRNA transcription#GO:0009301;regulation of biological process#GO:0050789 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000016149.1|UniProtKB=W5NGZ0 W5NGZ0 PTHR24060:SF29 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066 cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;signal transduction#GO:0007165;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR 1/5#P01040;Endogenous cannabinoid signaling#P05730>mGluR#P05748;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Metabotropic glutamate receptor group I pathway#P00041>mGluR1#P01062;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Metabotropic glutamate receptor group I pathway#P00041>mGluR5#P01061 LEPOC|Ensembl=ENSLOCG00000001477.1|UniProtKB=W5LZY6 W5LZY6 PISD PTHR10067:SF6 PHOSPHATIDYLSERINE DECARBOXYLASE PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000018216.1|UniProtKB=W5NNV8 W5NNV8 PTHR24241:SF139 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 5 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010441.1|UniProtKB=W5MWN8 W5MWN8 PTHR15603:SF3 SH3 DOMAIN-CONTAINING PROTEIN SH3 DOMAIN-BINDING PROTEIN 4 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to acid chemical#GO:0001101;negative regulation of response to stimulus#GO:0048585;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to amino acid stimulus#GO:0071230;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017280.1|UniProtKB=W5NL65 W5NL65 PTHR43981:SF4 ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013023.1|UniProtKB=W5N5Y4 W5N5Y4 PTHR23389:SF35 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 REPLICATION FACTOR C SUBUNIT 1 catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 DNA replication#P00017>RFC#P00529 LEPOC|Ensembl=ENSLOCG00000010465.1|UniProtKB=W5MWS3 W5MWS3 PTHR46090:SF3 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cellular localization#GO:0051641;localization within membrane#GO:0051668;organelle assembly#GO:0070925 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cell projection membrane#GO:0031253;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;plasma membrane region#GO:0098590 LEPOC|Ensembl=ENSLOCG00000007737.1|UniProtKB=W5MLY4 W5MLY4 PTHR10502:SF175 ANNEXIN ANNEXIN A13 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000012222.1|UniProtKB=W5N323 W5N323 PTHR21320:SF8 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008375.1|UniProtKB=W5MP74 W5MP74 PTHR10454:SF250 CASPASE CASPASE-2 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;positive regulation of apoptotic process#GO:0043065;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525;signaling#GO:0023052;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006500.1|UniProtKB=W5MHJ8 W5MHJ8 PTHR10627:SF78 SCP160 PROTEIN BICAUDAL C HOMOLOG 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000890.1|UniProtKB=W5LXY1 W5LXY1 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012398.1|UniProtKB=W5N3Q7 W5N3Q7 PTHR13501:SF10 CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000001067.1|UniProtKB=W5LYL9 W5LYL9 PTHR23189:SF136 RNA RECOGNITION MOTIF-CONTAINING SPLICING FACTOR, PROLINE- AND GLUTAMINE-RICH RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007304.1|UniProtKB=W5MKD4 W5MKD4 PTHR10064:SF1 60S RIBOSOMAL PROTEIN L22 RIBOSOMAL PROTEIN EL22-LIKE RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000010308.1|UniProtKB=W5MW72 W5MW72 PTHR21634:SF12 RE13835P FOLLICULIN-INTERACTING PROTEIN 1 protein binding#GO:0005515;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011979.1|UniProtKB=W5N270 W5N270 PTHR11848:SF133 TGF-BETA FAMILY INHIBIN BETA A CHAIN molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inhba#P06723;Gonadotropin-releasing hormone receptor pathway#P06664>Inhba/b#P06700;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000007486.1|UniProtKB=W5ML33 W5ML33 PTHR12157:SF28 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 4 structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 signal release#GO:0023061;trans-synaptic signaling#GO:0099537;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;cellular localization#GO:0051641;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular component organization#GO:0016043;signaling#GO:0023052;export from cell#GO:0140352;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of neurotransmitter secretion#GO:0046928;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;regulation of transport#GO:0051049;regulation of localization#GO:0032879;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177 intracellular anatomical structure#GO:0005622;presynaptic active zone#GO:0048786;cell junction#GO:0030054;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;cell cortex#GO:0005938;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004217.1|UniProtKB=W5M9I3 W5M9I3 PTHR11866:SF32 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E RECEPTOR 4 (SUBTYPE EP4) C signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of response to stress#GO:0080134;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;cell communication#GO:0007154;cellular response to alcohol#GO:0097306;cellular response to stimulus#GO:0051716;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to lipid#GO:0071396;regulation of response to external stimulus#GO:0032101;response to lipid#GO:0033993;response to chemical#GO:0042221;negative regulation of response to external stimulus#GO:0032102;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;response to oxygen-containing compound#GO:1901700;regulation of biological quality#GO:0065008;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to alcohol#GO:0097305;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014780.1|UniProtKB=W5NC44 W5NC44 PTHR10316:SF41 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 3 ISOFORM X1-RELATED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;cell junction#GO:0030054;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;synapse#GO:0045202;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016762.1|UniProtKB=W5NJB1 W5NJB1 PTHR42687:SF4 L-THREONINE 3-DEHYDROGENASE L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005344.1|UniProtKB=W5MDI0 W5MDI0 PTHR45973:SF35 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 43 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001428.1|UniProtKB=W5LZS0 W5LZS0 PTHR21258:SF46 DOCKING PROTEIN RELATED DOCKING PROTEIN 1 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dok-R#P00180 LEPOC|Ensembl=ENSLOCG00000012818.1|UniProtKB=W5N581 W5N581 PTHR13817:SF59 TITIN PROTEIN SIDEKICK-2 developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;homophilic cell-cell adhesion#GO:0007156;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;synapse organization#GO:0050808;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;synapse assembly#GO:0007416;cell junction organization#GO:0034330 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000012169.1|UniProtKB=W5N2W2 W5N2W2 PTHR23072:SF0 PHOSPHATIDYLINOSITOL GLYCAN-RELATED GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 2, CATALYTIC SUBUNIT catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780 protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003590.1|UniProtKB=W5M7C7 W5M7C7 PTHR15735:SF13 FCH AND DOUBLE SH3 DOMAINS PROTEIN FORMIN-BINDING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;regulation of actin filament-based process#GO:0032970;regulation of actin cytoskeleton organization#GO:0032956;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000015278.1|UniProtKB=W5NDU1 W5NDU1 PTHR43763:SF4 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 2 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008041.1|UniProtKB=W5MN07 W5MN07 PTHR13593:SF24 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000015816.1|UniProtKB=W5NFR2 W5NFR2 PTHR11950:SF7 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 nervous system development#GO:0007399;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;skeletal system development#GO:0001501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;hemopoiesis#GO:0030097;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;chondrocyte differentiation#GO:0002062;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;connective tissue development#GO:0061448;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;ossification#GO:0001503;system development#GO:0048731;cartilage development#GO:0051216;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;Runt transcription factor#PC00254 LEPOC|Ensembl=ENSLOCG00000017805.1|UniProtKB=W5NMQ0 W5NMQ0 PTHR11984:SF121 CONNEXIN GAP JUNCTION BETA-6 PROTEIN-RELATED passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;cell communication#GO:0007154 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000014431.1|UniProtKB=W5NAV3 W5NAV3 PTHR13440:SF7 BLOC-1 RELATED COMPLEX SUBUNIT 6 BLOC-1 RELATED COMPLEX SUBUNIT 6 localization#GO:0051179;organelle localization#GO:0051640;lysosome localization#GO:0032418 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000016465.1|UniProtKB=W5NI85 W5NI85 PTHR24103:SF611 E3 UBIQUITIN-PROTEIN LIGASE TRIM BBOX AND DUF4200 DOMAIN-CONTAINING PROTEIN-RELATED acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007372.1|UniProtKB=W5MKN3 W5MKN3 PTHR24072:SF23 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHO6 hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948 LEPOC|Ensembl=ENSLOCG00000011331.1|UniProtKB=W5MZX2 W5MZX2 PTHR46853:SF1 METHYLOSOME PROTEIN 50 METHYLOSOME PROTEIN WDR77 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009859.1|UniProtKB=W5MUJ2 W5MUJ2 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017218.1|UniProtKB=W5NKY0 W5NKY0 PTHR43313:SF43 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C ZGC:113142 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000005657.1|UniProtKB=W5MEN0 W5MEN0 PTHR22589:SF14 CARNITINE O-ACYLTRANSFERASE CHOLINE O-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 cell-cell signaling#GO:0007267;signaling#GO:0023052;biosynthetic process#GO:0009058;biological regulation#GO:0065007;anterograde trans-synaptic signaling#GO:0098916;cellular process#GO:0009987;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;neuromuscular synaptic transmission#GO:0007274;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuron projection#GO:0043005 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 LEPOC|Ensembl=ENSLOCG00000015580.1|UniProtKB=W5NEX2 W5NEX2 LSM8 PTHR15588:SF9 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U6 snRNP#GO:0005688;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000007708.1|UniProtKB=W5MLV2 W5MLV2 PTHR12625:SF2 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR PROTEIN LMBR1L transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014850.1|UniProtKB=W5NCC7 W5NCC7 PTHR13528:SF3 39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000017462.1|UniProtKB=W5NLQ8 W5NLQ8 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017301.1|UniProtKB=W5NL97 W5NL97 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000003816.1|UniProtKB=W5M874 W5M874 PTHR11706:SF116 SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;iron ion transmembrane transporter activity#GO:0005381 iron ion transport#GO:0006826;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;iron ion transmembrane transport#GO:0034755;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014236.1|UniProtKB=W5NA76 W5NA76 PTHR12381:SF41 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014946.1|UniProtKB=W5NCP2 W5NCP2 PTHR24214:SF1 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;heart development#GO:0007507;multicellular organismal process#GO:0032501;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular component organization#GO:0016043;circulatory system development#GO:0072359;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856 sarcomere#GO:0030017;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;adherens junction#GO:0005912;stress fiber#GO:0001725;cytoskeleton#GO:0005856;I band#GO:0031674;actin filament#GO:0005884;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cell-cell junction#GO:0005911;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;actomyosin#GO:0042641;myofibril#GO:0030016;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000009518.1|UniProtKB=W5MTC0 W5MTC0 PTHR21357:SF5 FAM172 FAMILY PROTEIN HOMOLOG CG10038 SI:CH73-41E3.7 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulatory ncRNA-mediated heterochromatin formation#GO:0031048 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009724.1|UniProtKB=W5MU18 W5MU18 PTHR31844:SF2 MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR-RELATED MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR structural protein#PC00211;myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000001069.1|UniProtKB=W5LYK0 W5LYK0 PTHR14978:SF0 BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN BETA-CATENIN-LIKE PROTEIN 1 mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000003640.1|UniProtKB=W5M7G1 W5M7G1 PTHR13874:SF9 ENDOTHELIN ENDOTHELIN-2 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 circulatory system process#GO:0003013;calcium ion homeostasis#GO:0055074;regulation of muscle contraction#GO:0006937;inorganic ion homeostasis#GO:0098771;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;regulation of muscle system process#GO:0090257;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;muscle system process#GO:0003012;homeostatic process#GO:0042592;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;muscle contraction#GO:0006936;cellular homeostasis#GO:0019725;regulation of smooth muscle contraction#GO:0006940;system process#GO:0003008;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;positive regulation of biological process#GO:0048518;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Endothelin signaling pathway#P00019>ET1-4#P00588;Endothelin signaling pathway#P00019>Pro ET1-4#P00571;Endothelin signaling pathway#P00019>Big ET1-4#P00574;Endothelin signaling pathway#P00019>Pre-pro ET1-4#P00576 LEPOC|Ensembl=ENSLOCG00000011263.1|UniProtKB=W5MZN5 W5MZN5 PTHR10811:SF6 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 transferase#PC00220;glycosyltransferase#PC00111 Notch signaling pathway#P00045>Fringe#P01107 LEPOC|Ensembl=ENSLOCG00000013932.1|UniProtKB=W5N969 W5N969 PTHR13678:SF2 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;protein targeting to vacuole#GO:0006623;intracellular protein transport#GO:0006886;protein targeting to membrane#GO:0006612;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;protein transport#GO:0015031;cellular localization#GO:0051641;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;localization#GO:0051179;protein metabolic process#GO:0019538;localization within membrane#GO:0051668;protein localization to vacuole#GO:0072665 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;ESCRT I complex#GO:0000813;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007089.1|UniProtKB=W5MJM4 W5MJM4 PTHR22802:SF459 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN CONTAINING 19A binding#GO:0005488;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007493.1|UniProtKB=W5ML38 W5ML38 PTHR48230:SF1 FAMILY NOT NAMED LIPID DESATURASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000001560.1|UniProtKB=W5M0A8 W5M0A8 PTHR16469:SF27 UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BB-RELATED LEPOC|Ensembl=ENSLOCG00000007300.1|UniProtKB=W5MKD8 W5MKD8 PTHR15735:SF17 FCH AND DOUBLE SH3 DOMAINS PROTEIN CDC42-INTERACTING PROTEIN 4 regulation of actin cytoskeleton organization#GO:0032956;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;membrane organization#GO:0061024;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000013980.1|UniProtKB=W5N9F6 W5N9F6 PTHR12658:SF1 BETA-TUBULIN COFACTOR D TUBULIN-SPECIFIC CHAPERONE D GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;binding#GO:0005488 protein folding#GO:0006457;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;microtubule cytoskeleton organization#GO:0000226;protein metabolic process#GO:0019538;cytoskeleton organization#GO:0007010;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013919.1|UniProtKB=W5N960 W5N960 PTHR10807:SF35 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3-PHOSPHATE PHOSPHATASE MTMR7 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 dephosphorylation#GO:0016311;lipid modification#GO:0030258;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000001559.1|UniProtKB=W5M081 W5M081 PTHR45889:SF5 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 3 cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609 synaptic membrane#GO:0097060;cell junction#GO:0030054;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015060.1|UniProtKB=W5ND31 W5ND31 PTHR12815:SF18 SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;cellular localization#GO:0051641;localization#GO:0051179;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742 LEPOC|Ensembl=ENSLOCG00000014015.1|UniProtKB=W5N9G6 W5N9G6 PTHR10221:SF9 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP#P00670;General transcription regulation#P00023>TBP-associated factors#P00658 LEPOC|Ensembl=ENSLOCG00000012599.1|UniProtKB=W5N4G7 W5N4G7 PTHR13298:SF11 CYTOSOLIC REGULATOR PIANISSIMO RAPAMYCIN-INSENSITIVE COMPANION OF MTOR protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;TORC2 signaling#GO:0038203;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;TOR signaling#GO:0031929;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 protein-containing complex#GO:0032991;TOR complex#GO:0038201;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000014104.1|UniProtKB=W5N9R6 W5N9R6 PTHR24125:SF0 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1A LEPOC|Ensembl=ENSLOCG00000003909.1|UniProtKB=W5M8F6 W5M8F6 PTHR11261:SF3 INTERPHOTORECEPTOR RETINOID-BINDING PROTEIN RETINOL-BINDING PROTEIN 3 binding#GO:0005488;small molecule binding#GO:0036094;alcohol binding#GO:0043178;lipid binding#GO:0008289 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 LEPOC|Ensembl=ENSLOCG00000012851.1|UniProtKB=W5N5A9 W5N5A9 PTHR10996:SF137 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013345.1|UniProtKB=W5N735 W5N735 PTHR46270:SF2 ARMADILLO-TYPE FOLD-RELATED TIR DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017777.1|UniProtKB=W5NMM2 W5NMM2 PTHR45773:SF11 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE FAMILY, MEMBER 6 positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;positive regulation of synapse assembly#GO:0051965;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;regulation of cell junction assembly#GO:1901888;system development#GO:0048731;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of multicellular organismal process#GO:0051239;positive regulation of cellular component biogenesis#GO:0044089;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;regulation of synapse organization#GO:0050807;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell morphogenesis#GO:0000902 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017318.1|UniProtKB=W5NLB4 W5NLB4 PTHR13935:SF133 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 1B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;sensory organ development#GO:0007423;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004264.1|UniProtKB=W5M9P3 W5M9P3 PTHR10887:SF552 DNA2/NAM7 HELICASE FAMILY HELICASE SENATAXIN double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;RNA binding#GO:0003723;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription termination#GO:0006353;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000008533.1|UniProtKB=W5MPR8 W5MPR8 PTHR47109:SF1 NUCLEOREDOXIN-LIKE PROTEIN 1 NUCLEOREDOXIN-LIKE PROTEIN 1 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015487.1|UniProtKB=W5NEK1 W5NEK1 PTHR24055:SF578 MITOGEN-ACTIVATED PROTEIN KINASE EKC_KEOPS COMPLEX SUBUNIT BUD32 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000006132.1|UniProtKB=W5MGA1 W5MGA1 PTHR16134:SF5 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;catabolic process#GO:0009056;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;photoperiodism#GO:0009648;macromolecule metabolic process#GO:0043170;response to external stimulus#GO:0009605;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of circadian rhythm#GO:0042752;cellular process#GO:0009987;response to radiation#GO:0009314;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498 intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013138.1|UniProtKB=W5N6D2 W5N6D2 PTHR11347:SF20 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000012787.1|UniProtKB=W5N524 W5N524 PTHR13968:SF21 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING RALY-LIKE PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016625.1|UniProtKB=W5NIS9 W5NIS9 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003205.1|UniProtKB=W5M5Y3 W5M5Y3 PTHR46906:SF1 HEAT SHOCK PROTEIN BETA-8 HEAT SHOCK PROTEIN BETA-8 response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to unfolded protein#GO:0006986;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cellular response to unfolded protein#GO:0034620 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;protein folding chaperone complex#GO:0101031;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008973.1|UniProtKB=W5MRC0 W5MRC0 PTHR11774:SF4 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000005894.1|UniProtKB=W5MFH3 W5MFH3 PTHR13183:SF4 AXONEMAL INNER ARM DYNEIN LIGHT CHAIN 28 AXONEMAL DYNEIN LIGHT INTERMEDIATE POLYPEPTIDE 1 protein binding#GO:0005515;binding#GO:0005488 intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;ciliary base#GO:0097546;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003138.1|UniProtKB=W5M5P8 W5M5P8 PTHR13317:SF5 TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130;regulation of cell projection assembly#GO:0060491;positive regulation of organelle organization#GO:0010638;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000004046.1|UniProtKB=W5M8X2 W5M8X2 PTHR24409:SF451 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 431-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000003558.1|UniProtKB=W5M753 W5M753 PTHR46063:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000005460.1|UniProtKB=W5MDX6 W5MDX6 PTHR24418:SF438 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 epidermal growth factor receptor signaling pathway#GO:0007173;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of cell motility#GO:2000147;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 Axon guidance mediated by Slit/Robo#P00008>Abl#P00347;Integrin signalling pathway#P00034>Abl#P00946 LEPOC|Ensembl=ENSLOCG00000000902.1|UniProtKB=W5LY20 W5LY20 PTHR43450:SF1 ASPARTYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000008563.1|UniProtKB=W5MPV6 W5MPV6 PTHR14402:SF8 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 2-LIKE-RELATED protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488 intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;membrane organization#GO:0061024;protein targeting#GO:0006605;protein insertion into membrane#GO:0051205;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010744.1|UniProtKB=W5MXQ5 W5MXQ5 PTHR12700:SF12 ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT D, MITOCHONDRIAL passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260 mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;organelle membrane#GO:0031090;transporter complex#GO:1990351;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007280.1|UniProtKB=W5MKA7 W5MKA7 PTHR15708:SF14 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED PROTEIN MTSS 1 ISOFORM X1 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;membrane organization#GO:0061024 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000003571.1|UniProtKB=W5M774 W5M774 PTHR11610:SF146 LIPASE TRIACYLGLYCEROL LIPASE hydrolase activity#GO:0016787;protein binding#GO:0005515;lipase activity#GO:0016298;catalytic activity#GO:0003824;binding#GO:0005488;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;regulation of biological process#GO:0050789;cellular process#GO:0009987;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015402.1|UniProtKB=W5NE96 W5NE96 PTHR33722:SF3 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT EPSILON spermatogenesis#GO:0007283;developmental process#GO:0032502;flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;cell maturation#GO:0048469;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;sperm capacitation#GO:0048240;male gamete generation#GO:0048232;developmental maturation#GO:0021700;spermatid development#GO:0007286;sexual reproduction#GO:0019953;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;cilium-dependent cell motility#GO:0060285;germ cell development#GO:0007281;sperm motility#GO:0097722;anatomical structure maturation#GO:0071695;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell differentiation#GO:0030154 membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;sperm principal piece#GO:0097228;plasma membrane protein complex#GO:0098797;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;9+2 motile cilium#GO:0097729;cilium#GO:0005929;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;sperm flagellum#GO:0036126;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012570.1|UniProtKB=W5N4C5 W5N4C5 PTHR45750:SF1 GH11602P HISTONE ACETYLTRANSFERASE KAT2A acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355 protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000000588.1|UniProtKB=W5LWZ3 W5LWZ3 PTHR33488:SF2 ZGC:162509 SUBFAMILY NOT NAMED LEPOC|Ensembl=ENSLOCG00000003110.1|UniProtKB=W5M5L1 W5M5L1 EIF3E PTHR10317:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;eukaryotic translation initiation factor 3 complex#GO:0005852 translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000001247.1|UniProtKB=W5LZ63 W5LZ63 PTHR24208:SF96 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1-BETA RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003899.1|UniProtKB=W5M8F5 W5M8F5 PTHR12097:SF0 SPLICING FACTOR 3B, SUBUNIT 1-RELATED SPLICING FACTOR 3B SUBUNIT 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;ribonucleoprotein complex biogenesis#GO:0022613;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000016067.1|UniProtKB=W5NGN8 W5NGN8 PTHR11848:SF320 TGF-BETA FAMILY NODAL-RELATED 1-RELATED signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000007087.1|UniProtKB=W5MJM3 W5MJM3 PTHR10612:SF63 APOLIPOPROTEIN D APOLIPOPROTEIN D cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;response to chemical#GO:0042221;response to stimulus#GO:0050896;lipid metabolic process#GO:0006629;response to oxygen-containing compound#GO:1901700;metabolic process#GO:0008152;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000008050.1|UniProtKB=W5MN22 W5MN22 PTHR23139:SF9 RNA-BINDING PROTEIN SPLICING FACTOR U2AF 65 KDA SUBUNIT nucleic acid binding#GO:0003676;binding#GO:0005488;pre-mRNA binding#GO:0036002;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U2-type prespliceosome#GO:0071004;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear speck#GO:0016607;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000003025.1|UniProtKB=W5M5A5 W5M5A5 PTHR24381:SF436 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 768 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000017584.1|UniProtKB=W5NM30 W5NM30 PTHR21029:SF1 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G PROTEIN SIGNALING 9-BINDING PROTEIN biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;response to radiation#GO:0009314;signal transduction#GO:0007165;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to external stimulus#GO:0009605;system process#GO:0003008;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;visual perception#GO:0007601;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;sensory perception of light stimulus#GO:0050953;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000016410.1|UniProtKB=W5NI07 W5NI07 PTHR45951:SF4 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED HOMOLOG 1 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004193.1|UniProtKB=W5M9E7 W5M9E7 PTHR12015:SF193 SMALL INDUCIBLE CYTOKINE A STROMAL CELL-DERIVED FACTOR 1 cytokine#PC00083 Axon guidance mediated by Slit/Robo#P00008>Sdf1#P00346 LEPOC|Ensembl=ENSLOCG00000015119.1|UniProtKB=W5ND98 W5ND98 PTHR11011:SF120 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753 organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004872.1|UniProtKB=W5MBV4 W5MBV4 PTHR14002:SF70 ENDOGLIN/TGF-BETA RECEPTOR TYPE III TRANSFORMING GROWTH FACTOR BETA RECEPTOR TYPE 3 ISOFORM X1 protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;cytokine receptor binding#GO:0005126;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein kinase activity#GO:0004672;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;transforming growth factor beta receptor activity#GO:0005024;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102;molecular transducer activity#GO:0060089;transforming growth factor beta binding#GO:0050431;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;cytokine binding#GO:0019955 cell surface receptor signaling pathway#GO:0007166;mesenchymal cell differentiation#GO:0048762;animal organ development#GO:0048513;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;mesenchyme development#GO:0060485;cellular developmental process#GO:0048869;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;tissue development#GO:0009888;response to transforming growth factor beta#GO:0071559;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004594.1|UniProtKB=W5MAU3 W5MAU3 PTHR10794:SF78 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD15 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008909.1|UniProtKB=W5MR45 W5MR45 TSHR PTHR24372:SF0 GLYCOPROTEIN HORMONE RECEPTOR THYROTROPIN RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000186.1|UniProtKB=W5LVQ3 W5LVQ3 PTHR10882:SF0 DIPHTHINE SYNTHASE DIPHTHINE METHYL ESTER SYNTHASE methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000005338.1|UniProtKB=W5MDH7 W5MDH7 PTHR45716:SF5 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810 endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008964.1|UniProtKB=W5MRB2 W5MRB2 PTHR23070:SF255 BCS1 AAA-TYPE ATPASE MITOCHONDRIAL CHAPERONE BCS1 cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex III assembly#GO:0034551;membrane organization#GO:0061024;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003650.1|UniProtKB=W5M7I0 W5M7I0 PTHR11440:SF18 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED PHOSPHATIDYLCHOLINE-STEROL ACYLTRANSFERASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000004467.1|UniProtKB=W5MAD4 W5MAD4 PTHR24264:SF84 TRYPSIN-RELATED UROKINASE-TYPE PLASMINOGEN ACTIVATOR serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 regulation of cell adhesion#GO:0030155;gene expression#GO:0010467;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;plasminogen activation#GO:0031639;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of cell adhesion mediated by integrin#GO:0033628;primary metabolic process#GO:0044238;zymogen activation#GO:0031638;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 Plasminogen activating cascade#P00050>pro-uPA#P01262;Blood coagulation#P00011>uPA#P00424;Blood coagulation#P00011>uPAR#P00433;Plasminogen activating cascade#P00050>uPA#P01243 LEPOC|Ensembl=ENSLOCG00000015197.1|UniProtKB=W5NDJ6 W5NDJ6 PTHR17695:SF11 SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000009195.1|UniProtKB=W5MS63 W5MS63 PTHR12299:SF30 HYALURONIC ACID-BINDING PROTEIN 4 INTRACELLULAR HYALURONAN-BINDING PROTEIN 4 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;regulation of translational initiation#GO:0006446;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010163.1|UniProtKB=W5MVM8 W5MVM8 PTHR14684:SF2 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000008062.1|UniProtKB=W5MN33 W5MN33 PTHR13976:SF30 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED EPITHELIAL SPLICING REGULATORY PROTEIN 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000014915.1|UniProtKB=W5NCK7 W5NCK7 PTHR45767:SF3 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O4 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 PI3 kinase pathway#P00048>FOXO#P01198 LEPOC|Ensembl=ENSLOCG00000003370.1|UniProtKB=W5M6H9 W5M6H9 PTHR12396:SF62 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG BINDING DOMAIN PROTEIN 2 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression, epigenetic#GO:0045814;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001858.1|UniProtKB=W5M196 W5M196 PTHR18763:SF0 WD-REPEAT PROTEIN 18 WD REPEAT-CONTAINING PROTEIN 18 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;DNA-templated DNA replication#GO:0006261;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear pre-replicative complex#GO:0005656;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoribonuclease complex#GO:1902555;intracellular organelle lumen#GO:0070013;pre-replicative complex#GO:0036387;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654 LEPOC|Ensembl=ENSLOCG00000012927.1|UniProtKB=W5N5L7 W5N5L7 PTHR12544:SF26 GLUTAMINASE GLUTAMINASE LIVER ISOFORM, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004559.1|UniProtKB=W5MAP6 W5MAP6 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000010597.1|UniProtKB=W5MX70 W5MX70 PTHR23137:SF1 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2B LEPOC|Ensembl=ENSLOCG00000004430.1|UniProtKB=W5MA91 W5MA91 PTHR46488:SF1 AP-5 COMPLEX SUBUNIT ZETA-1 AP-5 COMPLEX SUBUNIT ZETA-1 LEPOC|Ensembl=ENSLOCG00000008707.1|UniProtKB=W5MQD9 W5MQD9 PTHR14880:SF2 PROLINE AND SERINE-RICH PROTEIN 1 PROLINE AND SERINE-RICH PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009221.1|UniProtKB=W5MS93 W5MS93 PTHR12794:SF0 GEMIN2 GEM-ASSOCIATED PROTEIN 2 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 Sm-like protein family complex#GO:0120114;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;membrane-bounded organelle#GO:0043227;SMN complex#GO:0032797;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000016420.1|UniProtKB=W5NI19 W5NI19 PTHR47048:SF1 PROTEIN SCAF11 PROTEIN SCAF11 gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187 LEPOC|Ensembl=ENSLOCG00000005423.1|UniProtKB=W5MDW3 W5MDW3 PTHR42757:SF41 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED NEUROTRIMIN regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;cell adhesion#GO:0007155;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;regulation of cellular component organization#GO:0051128;regulation of synapse assembly#GO:0051963;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;cell-cell adhesion#GO:0098609;regulation of biological process#GO:0050789;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017858.1|UniProtKB=W5NMV2 W5NMV2 PTHR24377:SF1040 IP01015P-RELATED ZINC FINGER PROTEIN 467 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000004412.1|UniProtKB=W5MA81 W5MA81 PTHR24248:SF87 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(2) DOPAMINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;neurotransmitter receptor activity#GO:0030594 G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;regulation of trans-synaptic signaling#GO:0099177;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;negative regulation of signaling#GO:0023057;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;negative regulation of cell communication#GO:0010648;response to nitrogen compound#GO:1901698 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>DRD2#P06758;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965;Nicotine pharmacodynamics pathway#P06587>DRD2/ DRD3/ DRD4#P06603;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000005795.1|UniProtKB=W5MF41 W5MF41 PTHR12838:SF0 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012547.1|UniProtKB=W5N496 W5N496 PTHR13803:SF5 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24C SNARE binding#GO:0000149;zinc ion binding#GO:0008270;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043 vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000007908.1|UniProtKB=W5MMJ5 W5MMJ5 PTHR24007:SF7 BRCA1-ASSOCIATED PROTEIN BRCA1-ASSOCIATED PROTEIN ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 Ras protein signal transduction#GO:0007265;protein modification by small protein conjugation or removal#GO:0070647;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein modification process#GO:0036211;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;intracellular signaling cassette#GO:0141124 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000005868.1|UniProtKB=W5MFC8 W5MFC8 PTHR23308:SF36 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 SMAD NUCLEAR-INTERACTING PROTEIN 1 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA splicing factor#PC00148 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000005434.1|UniProtKB=W5MDV0 W5MDV0 PTHR24115:SF408 KINESIN-RELATED KINESIN-LIKE PROTEIN hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000011645.1|UniProtKB=W5N0Z7 W5N0Z7 PTHR11202:SF4 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER ENA_VASP-LIKE PROTEIN binding#GO:0005488;protein binding#GO:0005515 neuron projection guidance#GO:0097485;actin filament organization#GO:0007015;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of actin filament-based process#GO:0032970;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;axon guidance#GO:0007411;axon development#GO:0061564;system development#GO:0048731;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of supramolecular fiber organization#GO:1902903;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of anatomical structure size#GO:0090066;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;regulation of actin cytoskeleton organization#GO:0032956;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;regulation of biological quality#GO:0065008;neuron development#GO:0048666;axonogenesis#GO:0007409;positive regulation of organelle organization#GO:0010638;generation of neurons#GO:0048699;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254 cell junction#GO:0030054;anchoring junction#GO:0070161;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055 scaffold/adaptor protein#PC00226 Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516 LEPOC|Ensembl=ENSLOCG00000000467.1|UniProtKB=W5LWK2 W5LWK2 PTHR44281:SF4 SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG multicellular organismal reproductive process#GO:0048609;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;reproductive process#GO:0022414;gamete generation#GO:0007276;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;membraneless organelle assembly#GO:0140694;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;cell cycle#GO:0007049;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;spermatogenesis#GO:0007283;cytoskeleton organization#GO:0007010;male gamete generation#GO:0048232;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016889.1|UniProtKB=W5NJR9 W5NJR9 PTHR11246:SF3 PRE-MRNA SPLICING FACTOR CROOKED NECK-LIKE PROTEIN 1 cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000006197.1|UniProtKB=W5MGH5 W5MGH5 PTHR13578:SF18 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL3-RELATED chromatin binding#GO:0003682;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502 nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000018089.1|UniProtKB=W5NNI1 W5NNI1 PTHR24366:SF97 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 29 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000010801.1|UniProtKB=W5MXX8 W5MXX8 PTHR15302:SF0 E3 UBIQUITIN-PROTEIN LIGASE RNF103 E3 UBIQUITIN-PROTEIN LIGASE RNF103 aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;response to stimulus#GO:0050896;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;response to chemical#GO:0042221 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014887.1|UniProtKB=W5NCH4 W5NCH4 PTHR22406:SF5 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM SLAIN MOTIF-CONTAINING PROTEIN-LIKE regulation of microtubule-based process#GO:0032886;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;microtubule polymerization#GO:0046785;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule polymerization or depolymerization#GO:0031109;positive regulation of cellular process#GO:0048522;positive regulation of protein polymerization#GO:0032273;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;regulation of microtubule polymerization#GO:0031113;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;regulation of organelle organization#GO:0033043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cytoplasmic microtubule organization#GO:0031122;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010 organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752;microtubule plus-end#GO:0035371;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008647.1|UniProtKB=W5MQ61 W5MQ61 PTHR22803:SF74 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED SECRETORY PHOSPHOLIPASE A2 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000018281.1|UniProtKB=W5NP23 W5NP23 PTHR24247:SF17 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1D G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000011915.1|UniProtKB=W5N1Z1 W5N1Z1 PTHR18957:SF0 CENTLEIN CENTLEIN cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023 cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000011387.1|UniProtKB=W5N041 W5N041 PTHR44040:SF1 RETINOBLASTOMA-BINDING PROTEIN 5 RETINOBLASTOMA-BINDING PROTEIN 5 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000018035.1|UniProtKB=W5NNC7 W5NNC7 PTHR26451:SF854 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006914.1|UniProtKB=W5MJ09 W5MJ09 PTHR15829:SF16 PROTEIN KINASE PKN/PRK1, EFFECTOR RHO FAMILY-INTERACTING CELL POLARIZATION REGULATOR 1 ISOFORM X1 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000004590.1|UniProtKB=W5MAT9 W5MAT9 PTHR21290:SF69 SPHINGOMYELIN SYNTHETASE SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1 phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672 cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 LEPOC|Ensembl=ENSLOCG00000012674.1|UniProtKB=W5N4P1 W5N4P1 PTHR46046:SF3 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP10 LEPOC|Ensembl=ENSLOCG00000006366.1|UniProtKB=W5MH22 W5MH22 PTHR31450:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19 LRRC19 FAMILY MEMBER TYPE III ENDOSOME MEMBRANE PROTEIN TEMP LEPOC|Ensembl=ENSLOCG00000008818.1|UniProtKB=W5MQR7 W5MQR7 PTHR46630:SF2 TETRATRICOPEPTIDE REPEAT PROTEIN 29 TETRATRICOPEPTIDE REPEAT PROTEIN 29 cellular process#GO:0009987;cilium movement#GO:0003341;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729 LEPOC|Ensembl=ENSLOCG00000006756.1|UniProtKB=W5MIF1 W5MIF1 GOLPH3 PTHR12704:SF3 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3 phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;lipid binding#GO:0008289;cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein localization to cell periphery#GO:1990778;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;Golgi organization#GO:0007030;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytosol#GO:0005829;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000000006.1|UniProtKB=W5LV49 W5LV49 PTHR10683:SF44 TRANSALDOLASE TRANSALDOLASE transaldolase activity#GO:0004801;transketolase or transaldolase activity#GO:0016744;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 lyase#PC00144;metabolite interconversion enzyme#PC00262;aldolase#PC00044 Pentose phosphate pathway#P02762>Transaldolase#P03081 LEPOC|Ensembl=ENSLOCG00000012411.1|UniProtKB=W5N3S2 W5N3S2 PTHR10797:SF1 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 8 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 CCR4-NOT complex#GO:0030014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003729.1|UniProtKB=W5M7S4 W5M7S4 PTHR14350:SF2 ARGININE VASOPRESSIN-INDUCED PROTEIN 1 ARGININE VASOPRESSIN-INDUCED PROTEIN 1 positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 LEPOC|Ensembl=ENSLOCG00000010881.1|UniProtKB=W5MY89 W5MY89 PTHR19376:SF11 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;rRNA transcription#GO:0009303;transcription by RNA polymerase I#GO:0006360;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012739.1|UniProtKB=W5N4W3 W5N4W3 PTHR24161:SF17 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004379.1|UniProtKB=W5MA30 W5MA30 PTHR24416:SF390 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 protein kinase activity#GO:0004672;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713 positive regulation of MAPK cascade#GO:0043410;positive regulation of locomotion#GO:0040017;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;cell migration#GO:0016477;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;tube development#GO:0035295;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of signaling#GO:0023056;angiogenesis#GO:0001525;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;sprouting angiogenesis#GO:0002040;regulation of signaling#GO:0023051;circulatory system development#GO:0072359;response to stimulus#GO:0050896;signaling#GO:0023052;blood vessel morphogenesis#GO:0048514;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;vascular endothelial growth factor receptor signaling pathway#GO:0048010;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000949.1|UniProtKB=W5LY82 W5LY82 PTHR11566:SF39 DYNAMIN DYNAMIN-1-LIKE PROTEIN microtubule binding#GO:0008017;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;organelle organization#GO:0006996;cellular component organization#GO:0016043;programmed cell death#GO:0012501;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;mitochondrial fission#GO:0000266;peroxisome organization#GO:0007031;organelle localization#GO:0051640;mitochondrion localization#GO:0051646;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013823.1|UniProtKB=W5N8U2 W5N8U2 PTHR23503:SF137 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;carbohydrate transport#GO:0008643;transport#GO:0006810 perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000016846.1|UniProtKB=W5NJL4 W5NJL4 PTHR11006:SF47 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 8 histone modifying activity#GO:0140993;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000305.1|UniProtKB=W5LW35 W5LW35 PTHR11958:SF102 SODIUM/DICARBOXYLATE SYMPORTER-RELATED AMINO ACID TRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;sodium:dicarboxylate symporter activity#GO:0017153;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;L-amino acid transmembrane transporter activity#GO:0015179;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175 localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;L-glutamate import#GO:0051938;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic acid transport#GO:0015849;acidic amino acid transport#GO:0015800;transport#GO:0006810;carboxylic acid transport#GO:0046942;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000012716.1|UniProtKB=W5N4U1 W5N4U1 PTHR13148:SF0 PER1-RELATED GPI-SPECIFIC PHOSPHOLIPASE A2-LIKE PGAP3 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000000997.1|UniProtKB=W5LYB6 W5LYB6 PTHR15141:SF75 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN-A macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000012400.1|UniProtKB=W5N3R8 W5N3R8 PTHR10663:SF334 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 1 ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;ruffle#GO:0001726;cell projection membrane#GO:0031253;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000002709.1|UniProtKB=W5M469 W5M469 PTHR10699:SF15 NEUROMODULIN NEUROMODULIN calmodulin binding#GO:0005516;carbohydrate derivative binding#GO:0097367;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;protein binding#GO:0005515 neuron differentiation#GO:0030182;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;regeneration#GO:0031099;cell morphogenesis involved in neuron differentiation#GO:0048667;generation of neurons#GO:0048699;tissue regeneration#GO:0042246;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental growth#GO:0048589;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cell recognition#GO:0008037;system development#GO:0048731;anatomical structure development#GO:0048856 postsynaptic density#GO:0014069;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;cytoplasm#GO:0005737;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic specialization#GO:0099572 LEPOC|Ensembl=ENSLOCG00000006478.1|UniProtKB=W5MHG3 W5MHG3 PTHR24394:SF16 ZINC FINGER PROTEIN HYPERMETHYLATED IN CANCER 1 PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000017311.1|UniProtKB=W5NLA7 W5NLA7 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008204.1|UniProtKB=W5MNL6 W5MNL6 PTHR11633:SF5 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR C growth factor receptor binding#GO:0070851;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of ERK1 and ERK2 cascade#GO:0070372;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;signaling#GO:0023052;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of locomotion#GO:0040017;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224 LEPOC|Ensembl=ENSLOCG00000009029.1|UniProtKB=W5MRJ8 W5MRJ8 PTHR24006:SF852 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 16 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000013339.1|UniProtKB=W5N742 W5N742 PTHR11932:SF168 CULLIN CULLIN-1 ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625 modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Cul-1#P01239 LEPOC|Ensembl=ENSLOCG00000011964.1|UniProtKB=W5N257 W5N257 PTHR24418:SF219 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE TEC phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000004807.1|UniProtKB=W5MBK8 W5MBK8 PTHR28375:SF1 PROTEIN HINDERIN PROTEIN HINDERIN LEPOC|Ensembl=ENSLOCG00000011750.1|UniProtKB=W5N1D7 W5N1D7 PTHR23187:SF4 FLJ44216 PROTEIN-RELATED SKI_DACH DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000015608.1|UniProtKB=W5NF09 W5NF09 PTHR24264:SF85 TRYPSIN-RELATED PLASMINOGEN ACTIVATOR catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;zymogen activation#GO:0031638;primary metabolic process#GO:0044238;plasminogen activation#GO:0031639;biosynthetic process#GO:0009058;cell migration#GO:0016477;protein maturation#GO:0051604;gene expression#GO:0010467;cell motility#GO:0048870;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012287.1|UniProtKB=W5N3B4 W5N3B4 PTHR24044:SF320 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN 4 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;Notch signaling pathway#GO:0007219;negative regulation of cellular process#GO:0048523;negative regulation of Notch signaling pathway#GO:0045746;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 intercellular signal molecule#PC00207 Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Delta#P01116 LEPOC|Ensembl=ENSLOCG00000013135.1|UniProtKB=W5N6B8 W5N6B8 PTHR10342:SF69 ARYLSULFATASE ARYLSULFATASE J catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 LEPOC|Ensembl=ENSLOCG00000009889.1|UniProtKB=W5MUP2 W5MUP2 PTHR24346:SF1 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MAP_MICROTUBULE AFFINITY-REGULATING KINASE 3 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005715.1|UniProtKB=W5MET6 W5MET6 PTHR33560:SF1 PROTEIN FAM227B PROTEIN FAM227A LEPOC|Ensembl=ENSLOCG00000008621.1|UniProtKB=W5MQ19 W5MQ19 PTHR46156:SF1 CCCH ZINGC FINGER ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000000782.1|UniProtKB=W5LXK9 W5LXK9 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000011792.1|UniProtKB=W5N1I6 W5N1I6 PTHR10825:SF74 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 6 chromatin binding#GO:0003682;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000007425.1|UniProtKB=W5MKX6 W5MKX6 PTHR10027:SF9 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY T MEMBER 2 passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000005141.1|UniProtKB=W5MCT1 W5MCT1 PTHR10913:SF16 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 3 protein-containing complex binding#GO:0044877;activin binding#GO:0048185;binding#GO:0005488 cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000003908.1|UniProtKB=W5M8F4 W5M8F4 PTHR15402:SF2 TRANSCRIPTION FACTOR-LIKE 5 PROTEIN TRANSCRIPTION FACTOR LIKE 5 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000005091.1|UniProtKB=W5MCM3 W5MCM3 PTHR46013:SF9 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000018062.1|UniProtKB=W5NNF4 W5NNF4 PTHR10003:SF77 SUPEROXIDE DISMUTASE CU-ZN -RELATED EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN] cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;copper ion binding#GO:0005507 response to stimulus#GO:0050896;response to toxic substance#GO:0009636;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;cellular process#GO:0009987;response to stress#GO:0006950;response to reactive oxygen species#GO:0000302;cellular response to chemical stress#GO:0062197;superoxide metabolic process#GO:0006801;response to oxidative stress#GO:0006979;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016908.1|UniProtKB=W5NJU5 W5NJU5 PTHR24301:SF17 THROMBOXANE-A SYNTHASE THROMBOXANE-A SYNTHASE catalytic activity#GO:0003824;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 isomerase#PC00135;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011824.1|UniProtKB=W5N1M9 W5N1M9 PTHR45659:SF10 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001889.1|UniProtKB=W5M1D6 W5M1D6 PTHR16504:SF4 5'(3')-DEOXYRIBONUCLEOTIDASE 5'(3')-DEOXYRIBONUCLEOTIDASE, MITOCHONDRIAL phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 LEPOC|Ensembl=ENSLOCG00000013609.1|UniProtKB=W5N829 W5N829 PTHR45702:SF4 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 10 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;biological regulation#GO:0065007;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;proteolysis#GO:0006508;cell communication#GO:0007154;protein metabolic process#GO:0019538 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 LEPOC|Ensembl=ENSLOCG00000013040.1|UniProtKB=W5N603 W5N603 PTHR21646:SF11 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 50 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;Ras protein signal transduction#GO:0007265;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of response to biotic stimulus#GO:0002833;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of Wnt signaling pathway#GO:0030111;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;positive regulation of immune system process#GO:0002684;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;regulation of protein stability#GO:0031647;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of cellular component biogenesis#GO:0044089;regulation of response to external stimulus#GO:0032101;endomembrane system organization#GO:0010256;intracellular signaling cassette#GO:0141124;cellular component organization or biogenesis#GO:0071840;positive regulation of response to external stimulus#GO:0032103;endosome organization#GO:0007032;vesicle organization#GO:0016050 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;postsynaptic density#GO:0014069;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cytoplasm#GO:0005737;cytosol#GO:0005829;midbody#GO:0030496;postsynapse#GO:0098794 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000006892.1|UniProtKB=W5MIX4 W5MIX4 PTHR12015:SF165 SMALL INDUCIBLE CYTOKINE A CHEMOKINE (C-C MOTIF) LIGAND 34A, DUPLICATE 3 PRECURSOR-RELATED cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000008476.1|UniProtKB=W5MPP0 W5MPP0 PTHR23345:SF29 VITELLOGENIN-RELATED VITELLOGENIN 3, PHOSVITINLESS ISOFORM X1 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 response to chemical#GO:0042221;response to stimulus#GO:0050896;response to lipid#GO:0033993;response to estradiol#GO:0032355;response to oxygen-containing compound#GO:1901700 storage protein#PC00210 LEPOC|Ensembl=ENSLOCG00000003238.1|UniProtKB=W5M615 W5M615 PTHR24388:SF109 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 221-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000012137.1|UniProtKB=W5N2T1 W5N2T1 PTHR23509:SF32 PA-PL1 PHOSPHOLIPASE FAMILY PHOSPHOLIPASE DDHD1 hydrolase activity#GO:0016787;glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phospholipase#PC00186;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016546.1|UniProtKB=W5NIH4 W5NIH4 PTHR24034:SF94 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-7 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000013204.1|UniProtKB=W5N6L0 W5N6L0 PTHR23503:SF133 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 import across plasma membrane#GO:0098739;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000002401.1|UniProtKB=W5M361 W5M361 PTHR10924:SF27 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER 4 membrane#GO:0016020;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000013334.1|UniProtKB=W5N728 W5N728 PTHR10901:SF15 TROPOMODULIN TROPOMODULIN-2 protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;actin filament organization#GO:0007015;system process#GO:0003008;cellular developmental process#GO:0048869;developmental process#GO:0032502;muscle contraction#GO:0006936;multicellular organismal process#GO:0032501 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000007691.1|UniProtKB=W5MLT1 W5MLT1 PTHR24042:SF8 NEL HOMOLOG NELL (NEURAL EGFL LIKE) FAMILY MEMBER 3 heparin binding#GO:0008201;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000015444.1|UniProtKB=W5NEF3 W5NEF3 PTHR10183:SF385 CALPAIN CALPAIN-9 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000009261.1|UniProtKB=W5MSE7 W5MSE7 PTHR11984:SF117 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell communication#GO:0007154;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;regulation of biological process#GO:0050789 cell junction#GO:0030054;anchoring junction#GO:0070161;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000009591.1|UniProtKB=W5MTK6 W5MTK6 PTHR12787:SF0 RIBOSOMAL RNA-PROCESSING PROTEIN 8 RIBOSOMAL RNA-PROCESSING PROTEIN 8 RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular process#GO:0009987;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;nucleolus organization#GO:0007000;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000007930.1|UniProtKB=W5MMM0 W5MMM0 PTHR44444:SF4 PROTEIN SEL-1 HOMOLOG 3 PROTEIN SEL-1 HOMOLOG 3 PRECURSOR LEPOC|Ensembl=ENSLOCG00000007718.1|UniProtKB=W5MLX7 W5MLX7 PTHR12419:SF117 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 3 cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000002928.1|UniProtKB=W5M4Y9 W5M4Y9 PTHR24409:SF345 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 276 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008061.1|UniProtKB=W5MN25 W5MN25 PTHR12932:SF18 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;positive regulation of protein polymerization#GO:0032273;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;positive regulation of cellular component organization#GO:0051130;microtubule bundle formation#GO:0001578;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;protein polymerization#GO:0051258 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000007499.1|UniProtKB=W5ML57 W5ML57 PTHR18935:SF9 GOLGIN SUBFAMILY A MEMBER 4-LIKE ISOFORM X1 JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000009899.1|UniProtKB=W5MUP3 W5MUP3 PTHR13817:SF181 TITIN IMMUNOGLOBULIN LIKE AND FIBRONECTIN TYPE III DOMAIN CONTAINING 1 structural molecule activity#GO:0005198 anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;cell development#GO:0048468;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell differentiation#GO:0030154;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle cell development#GO:0055001 contractile muscle fiber#GO:0043292;A band#GO:0031672;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;M band#GO:0031430;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006971.1|UniProtKB=W5MJ74 W5MJ74 PTHR12167:SF4 C-TYPE NATRIURETIC PEPTIDE C-TYPE NATRIURETIC PEPTIDE-LIKE ISOFORM X1 binding#GO:0005488;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000005710.1|UniProtKB=W5MET1 W5MET1 PTHR12837:SF8 POLY ADP-RIBOSE GLYCOHYDROLASE POLY(ADP-RIBOSE) GLYCOHYDROLASE ISOFORM X1-RELATED hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;macromolecule metabolic process#GO:0043170;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organophosphate metabolic process#GO:0019637;nucleotide-sugar metabolic process#GO:0009225;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;ribonucleotide metabolic process#GO:0009259;regulation of cellular response to stress#GO:0080135;nucleotide metabolic process#GO:0009117;regulation of DNA metabolic process#GO:0051052;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000007152.1|UniProtKB=W5MJY3 W5MJY3 PTHR24223:SF339 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 6 xenobiotic transmembrane transporter activity#GO:0042910;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000009015.1|UniProtKB=W5MRH9 W5MRH9 PTHR23073:SF24 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 4 macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;proteasome complex#GO:0000502 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000014618.1|UniProtKB=W5NBI3 W5NBI3 PTHR16705:SF5 COMPLEXIN COMPLEXIN-3 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;vesicle-mediated transport in synapse#GO:0099003;regulation of transport#GO:0051049;regulation of localization#GO:0032879;exocytosis#GO:0006887;regulated exocytosis#GO:0045055;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;export from cell#GO:0140352;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of signaling#GO:0023051 axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell projection#GO:0042995;neuron projection terminus#GO:0044306;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;synapse#GO:0045202;axon terminus#GO:0043679;cell junction#GO:0030054;neuron projection#GO:0043005;presynapse#GO:0098793;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000011876.1|UniProtKB=W5N1W1 W5N1W1 PTHR22576:SF42 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 ISOFORM X1 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000007763.1|UniProtKB=W5MM18 W5MM18 EIF6 PTHR10784:SF0 TRANSLATION INITIATION FACTOR 6 EUKARYOTIC TRANSLATION INITIATION FACTOR 6 ribonucleoprotein complex binding#GO:0043021;ribosomal large subunit binding#GO:0043023;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488 establishment of organelle localization#GO:0051656;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;localization#GO:0051179;protein-RNA complex assembly#GO:0022618;nuclear transport#GO:0051169;nuclear export#GO:0051168;rRNA processing#GO:0006364;organelle assembly#GO:0070925;organelle localization#GO:0051640;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;rRNA metabolic process#GO:0016072;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000007306.1|UniProtKB=W5MKE3 W5MKE3 PTHR45930:SF3 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A1 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic density#GO:0014069 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009792.1|UniProtKB=W5MUB1 W5MUB1 PTHR14619:SF1 NEURON-DERIVED NEUROTROPHIC FACTOR PROTEIN NDNF glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;heparin binding#GO:0008201 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000006447.1|UniProtKB=W5MHD0 W5MHD0 PTHR10779:SF17 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 1 binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000006173.1|UniProtKB=W5MGF2 W5MGF2 PTHR20275:SF30 NAD KINASE NAD(+) KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;NADP+ metabolic process#GO:0006739;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;pyridine-containing compound metabolic process#GO:0072524;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000002366.1|UniProtKB=W5M316 W5M316 PTHR22791:SF37 RING-TYPE DOMAIN-CONTAINING PROTEIN RING FINGER PROTEIN 223 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010689.1|UniProtKB=W5MXK5 W5MXK5 PTHR12587:SF5 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-4 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 presynapse#GO:0098793;cellular anatomical structure#GO:0110165;synapse#GO:0045202;presynaptic active zone#GO:0048786;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001515.1|UniProtKB=W5M041 W5M041 PTHR13280:SF16 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 1 protein localization to organelle#GO:0033365;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;cellular process#GO:0009987;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to Golgi apparatus#GO:0034067;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668 LEPOC|Ensembl=ENSLOCG00000010033.1|UniProtKB=W5MV58 W5MV58 TRAPPC2 PTHR12403:SF1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-RELATED cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011738.1|UniProtKB=W5N1C3 W5N1C3 PTHR12532:SF12 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000010761.1|UniProtKB=W5MXT0 W5MXT0 PTHR11964:SF38 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 biosynthetic process#GO:0009058;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000002435.1|UniProtKB=W5M3A9 W5M3A9 PTHR15739:SF4 ZINC FINGER PROTEIN F-BOX ONLY PROTEIN 41 LEPOC|Ensembl=ENSLOCG00000018353.1|UniProtKB=W5NP95 W5NP95 PTHR11819:SF150 SOLUTE CARRIER FAMILY 5 SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M-RELATED secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014335.1|UniProtKB=W5NAM9 W5NAM9 PTHR24023:SF1128 COLLAGEN ALPHA COLLAGEN ALPHA-6(IV) CHAIN ISOFORM X1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000002955.1|UniProtKB=W5M521 W5M521 PTHR23051:SF0 SOLUTE CARRIER FAMILY 35, MEMBER F5 SOLUTE CARRIER FAMILY 35 MEMBER F5 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000012358.1|UniProtKB=W5N3L4 W5N3L4 PTHR11969:SF13 MAX DIMERIZATION, MAD MAX-INTERACTING PROTEIN 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000013804.1|UniProtKB=W5N8R2 W5N8R2 PTHR34491:SF156 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED AUGMIN COMPLEX SUBUNIT DGT5 LEPOC|Ensembl=ENSLOCG00000003627.1|UniProtKB=W5M7E8 W5M7E8 PTHR10760:SF14 TORSIN TORSIN-1B cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 intracellular protein localization#GO:0008104;nuclear envelope organization#GO:0006998;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;protein localization to nucleus#GO:0034504;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein localization to organelle#GO:0033365 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;organelle envelope#GO:0031967;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;nucleus#GO:0005634 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008756.1|UniProtKB=W5MQL2 W5MQL2 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011041.1|UniProtKB=W5MYU5 W5MYU5 PTHR22984:SF29 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE PIM-1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of TORC1 signaling#GO:1904263;regulation of TOR signaling#GO:0032006;regulation of mitotic cell cycle#GO:0007346;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011651.1|UniProtKB=W5N1A0 W5N1A0 PTHR45615:SF44 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-13 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;actin binding#GO:0003779;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657 system process#GO:0003008;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000010304.1|UniProtKB=W5MW63 W5MW63 PTHR28388:SF1 TRANSMEMBRANE PROTEIN 237 TRANSMEMBRANE PROTEIN 237 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000001059.1|UniProtKB=W5LYI7 W5LYI7 PTHR12767:SF5 BCL7 RELATED B-CELL CLL_LYMPHOMA 7 PROTEIN FAMILY MEMBER B cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000013167.1|UniProtKB=W5N6F9 W5N6F9 PTHR11691:SF62 TYPE I INTERFERON INTERFERON PHI 2-RELATED signal transduction#GO:0007165;lymphocyte activation involved in immune response#GO:0002285;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;T cell activation involved in immune response#GO:0002286;response to cytokine#GO:0034097;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;defense response to other organism#GO:0098542;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;cell surface receptor signaling pathway#GO:0007166;natural killer cell activation#GO:0030101;humoral immune response#GO:0006959;B cell activation#GO:0042113;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;B cell activation involved in immune response#GO:0002312;response to peptide#GO:1901652;cell activation involved in immune response#GO:0002263;immune response#GO:0006955;biological regulation#GO:0065007;response to other organism#GO:0051707;adaptive immune response#GO:0002250;multicellular organismal process#GO:0032501;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;response to nitrogen compound#GO:1901698;cell communication#GO:0007154 interferon superfamily#PC00127;cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000015547.1|UniProtKB=W5NES8 W5NES8 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005889.1|UniProtKB=W5MFF6 W5MFF6 PTHR10024:SF250 SYNAPTOTAGMIN SYNAPTOTAGMIN-13 SNARE binding#GO:0000149;phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;protein binding#GO:0005515 signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;regulation of exocytosis#GO:0017157;cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;secretion#GO:0046903;positive regulation of cellular process#GO:0048522;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;export from cell#GO:0140352;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of cellular component organization#GO:0051128;regulation of neurotransmitter secretion#GO:0046928;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;synaptic vesicle exocytosis#GO:0016079;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;cellular process#GO:0009987;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;regulated exocytosis#GO:0045055;regulation of transport#GO:0051049;positive regulation of vesicle fusion#GO:0031340;regulation of localization#GO:0032879;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003 cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;organelle membrane#GO:0031090;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;intracellular vesicle#GO:0097708;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000001391.1|UniProtKB=W5LZM7 W5LZM7 PTHR23101:SF129 RAB GDP/GTP EXCHANGE FACTOR RAB GUANINE NUCLEOTIDE EXCHANGE FACTOR (GEF) 1-RELATED protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;cytosol#GO:0005829;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000000527.1|UniProtKB=W5LWS2 W5LWS2 PTHR13874:SF12 ENDOTHELIN ENDOTHELIN-3A signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of system process#GO:0044057;regulation of anatomical structure size#GO:0090066;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;muscle contraction#GO:0006936;regulation of smooth muscle contraction#GO:0006940;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;system process#GO:0003008;regulation of systemic arterial blood pressure#GO:0003073;monoatomic ion homeostasis#GO:0050801;regulation of blood pressure#GO:0008217;positive regulation of biological process#GO:0048518;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;calcium ion homeostasis#GO:0055074;circulatory system process#GO:0003013;regulation of muscle contraction#GO:0006937;inorganic ion homeostasis#GO:0098771;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;regulation of muscle system process#GO:0090257;positive regulation of multicellular organismal process#GO:0051240;muscle system process#GO:0003012;regulation of biological process#GO:0050789;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000015169.1|UniProtKB=W5NDH0 W5NDH0 PTHR24092:SF38 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IG intramembrane lipid carrier activity#GO:0140303;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;recycling endosome#GO:0055037;endoplasmic reticulum#GO:0005783;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000008634.1|UniProtKB=W5MQ35 W5MQ35 PTHR23216:SF2 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000002522.1|UniProtKB=W5M3K8 W5M3K8 PTHR12783:SF5 RALA BINDING PROTEIN 1 RALBP1 RALA-BINDING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;vesicle-mediated transport#GO:0016192;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000008295.1|UniProtKB=W5MNW4 W5MNW4 PTHR13580:SF13 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE_SERINE-RICH NUCLEAR PROTEIN 3 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013451.1|UniProtKB=W5N7H2 W5N7H2 PTHR46166:SF2 HOMEOBOX DOMAIN-CONTAINING PROTEIN HOMEOBOX PROTEIN HOX-B8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016804.1|UniProtKB=W5NJG0 W5NJG0 PTHR24369:SF172 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000013413.1|UniProtKB=W5N7C8 W5N7C8 PTHR12990:SF10 ARMET-LIKE PROTEIN MESENCEPHALIC ASTROCYTE-DERIVED NEUROTROPHIC FACTOR growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular component organization#GO:0016043;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017456.1|UniProtKB=W5NLQ2 W5NLQ2 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002571.1|UniProtKB=W5M3R4 W5M3R4 PTHR20870:SF0 BARDET-BIEDL SYNDROME 1 PROTEIN BBSOME COMPLEX MEMBER BBS1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;protein localization to cilium#GO:0061512;organelle assembly#GO:0070925;non-motile cilium assembly#GO:1905515;localization#GO:0051179;cilium organization#GO:0044782 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;BBSome#GO:0034464;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930 LEPOC|Ensembl=ENSLOCG00000017246.1|UniProtKB=W5NL22 W5NL22 PTHR11630:SF48 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA HELICASE MCM9 DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007640.1|UniProtKB=W5MLL7 W5MLL7 PTHR45626:SF17 TRANSCRIPTION TERMINATION FACTOR 2-RELATED DNA-DEPENDENT ATPASE_E3 UBIQUITIN-PROTEIN LIGASE HLTF catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000009970.1|UniProtKB=W5MUY3 W5MUY3 PTHR12967:SF0 PROTEIN SHQ1 HOMOLOG PROTEIN SHQ1 HOMOLOG cellular component assembly#GO:0022607;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000005340.1|UniProtKB=W5MDH6 W5MDH6 PTHR21294:SF8 ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000401.1|UniProtKB=W5LWD1 W5LWD1 PTHR23050:SF536 CALCIUM BINDING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000000496.1|UniProtKB=W5LWP1 W5LWP1 PTHR24393:SF151 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 956 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015792.1|UniProtKB=W5NFN2 W5NFN2 PTHR10333:SF114 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 3 histone reader activity#GO:0140566;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008286.1|UniProtKB=W5MNV5 W5MNV5 PTHR22591:SF1 XIN XIN ACTIN-BINDING REPEAT-CONTAINING PROTEIN 2 cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;actin filament bundle#GO:0032432;cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;stress fiber#GO:0001725;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell-substrate junction#GO:0030055;intracellular membraneless organelle#GO:0043232;focal adhesion#GO:0005925;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000014949.1|UniProtKB=W5NCP6 W5NCP6 PTHR11636:SF44 POU DOMAIN BRAIN-SPECIFIC HOMEOBOX_POU DOMAIN PROTEIN 3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000004067.1|UniProtKB=W5M907 W5M907 PTHR31336:SF3 LIN37 HOMOLOG PROTEIN LIN-37 HOMOLOG negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000012359.1|UniProtKB=W5N3K6 W5N3K6 PTHR21615:SF2 CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1 CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1 Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000012304.1|UniProtKB=W5N3E8 W5N3E8 PTHR45685:SF2 HELICASE SRCAP-RELATED CHROMATIN-REMODELING ATPASE INO80 hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;histone binding#GO:0042393 response to stimulus#GO:0050896;chromatin remodeling#GO:0006338;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974 INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;Ino80 complex#GO:0031011;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000012540.1|UniProtKB=W5N485 W5N485 PTHR31901:SF9 GH3 DOMAIN-CONTAINING PROTEIN GH3 DOMAIN-CONTAINING PROTEIN ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000015919.1|UniProtKB=W5NG43 W5NG43 PTHR21032:SF3 G PATCH DOMAIN-CONTAINING PROTEIN 11 G PATCH DOMAIN-CONTAINING PROTEIN 11 system process#GO:0003008;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;multicellular organismal process#GO:0032501;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;sensory perception#GO:0007600;nervous system process#GO:0050877;RNA biosynthetic process#GO:0032774;visual perception#GO:0007601;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;sensory perception of light stimulus#GO:0050953 intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000012128.1|UniProtKB=W5N2R5 W5N2R5 PTHR22834:SF19 NUCLEAR FUSION PROTEIN FUS2 DYNAMIN-BINDING PROTEIN molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003067.1|UniProtKB=W5M5H4 W5M5H4 PTHR10066:SF68 BETA-GLUCURONIDASE BETA-GLUCURONIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;carbohydrate binding#GO:0030246;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;aminoglycan metabolic process#GO:0006022;glycosaminoglycan catabolic process#GO:0006027;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002487.1|UniProtKB=W5M3G5 W5M3G5 PTHR45787:SF8 LD11652P LIM DOMAIN ONLY 4-RELATED transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000016630.1|UniProtKB=W5NIT3 W5NIT3 PTHR43782:SF2 ARGINASE ARGINASE-1 transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 metabolic process#GO:0008152;regulation of leukocyte proliferation#GO:0070663;negative regulation of T cell proliferation#GO:0042130;regulation of mononuclear cell proliferation#GO:0032944;cellular process#GO:0009987;regulation of T cell activation#GO:0050863;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;arginine metabolic process#GO:0006525;regulation of multicellular organismal process#GO:0051239;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;small molecule metabolic process#GO:0044281;regulation of lymphocyte activation#GO:0051249;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cell activation#GO:0050866;negative regulation of cell population proliferation#GO:0008285;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;negative regulation of cell adhesion#GO:0007162;amino acid metabolic process#GO:0006520;negative regulation of immune system process#GO:0002683;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of T cell proliferation#GO:0042129;negative regulation of leukocyte cell-cell adhesion#GO:1903038 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017042.1|UniProtKB=W5NKB2 W5NKB2 PTHR11339:SF361 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED VON WILLEBRAND FACTOR structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 biological regulation#GO:0065007;regulation of body fluid levels#GO:0050878;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;cellular process#GO:0009987;coagulation#GO:0050817;response to stress#GO:0006950;hemostasis#GO:0007599;response to wounding#GO:0009611;blood coagulation#GO:0007596;regulation of biological quality#GO:0065008;wound healing#GO:0042060;cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Blood coagulation#P00011>vWF#P00448;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863 LEPOC|Ensembl=ENSLOCG00000006332.1|UniProtKB=W5MGY4 W5MGY4 PTHR22923:SF89 CEREBELLIN-RELATED CEREBELLIN 18 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015768.1|UniProtKB=W5NFK3 W5NFK3 PTHR28366:SF1 CHROMOSOME 1 OPEN READING FRAME 131 40S SMALL SUBUNIT PROCESSOME ASSEMBLY FACTOR 1 LEPOC|Ensembl=ENSLOCG00000012253.1|UniProtKB=W5N368 W5N368 PTHR46860:SF1 CHROMOBOX PROTEIN HOMOLOG 2 CHROMOBOX PROTEIN HOMOLOG 2 chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;histone H3K9me2/3 reader activity#GO:0062072;histone reader activity#GO:0140566 negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 chromatin#GO:0000785;nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151 LEPOC|Ensembl=ENSLOCG00000007544.1|UniProtKB=W5ML95 W5ML95 PTHR12191:SF21 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP4 symporter activity#GO:0015293;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000017979.1|UniProtKB=W5NN71 W5NN71 PTHR15066:SF0 TRANSMEMBRANE PROTEIN 187 TRANSMEMBRANE PROTEIN 187 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;transport vesicle#GO:0030133;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000011309.1|UniProtKB=W5MZT5 W5MZT5 PTHR24028:SF236 CADHERIN-87A PROTOCADHERIN ALPHA-C1 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000017860.1|UniProtKB=W5NMV4 W5NMV4 PTHR11767:SF6 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 1 gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000003648.1|UniProtKB=W5M7H9 W5M7H9 PTHR14493:SF37 UNKEMPT FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE UNKL-RELATED LEPOC|Ensembl=ENSLOCG00000004042.1|UniProtKB=W5M8X0 W5M8X0 PTHR12864:SF89 RAN BINDING PROTEIN 9-RELATED SPRY DOMAIN-CONTAINING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008614.1|UniProtKB=W5MQ10 W5MQ10 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000773.1|UniProtKB=W5LXK1 W5LXK1 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014268.1|UniProtKB=W5NAA5 W5NAA5 PTHR45817:SF8 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 1 oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000017919.1|UniProtKB=W5NN13 W5NN13 PTHR13318:SF273 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 14 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 transferase complex#GO:1990234;catalytic complex#GO:1902494;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 LEPOC|Ensembl=ENSLOCG00000011826.1|UniProtKB=W5N1N3 W5N1N3 PTHR19282:SF470 TETRASPANIN TETRASPANIN-17 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005537.1|UniProtKB=W5ME75 W5ME75 PTHR14066:SF10 ATRIAL NATRIURETIC FACTOR PRECURSOR NATRIURETIC PEPTIDES B signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;system process#GO:0003008;ribonucleotide biosynthetic process#GO:0009260;regulation of blood pressure#GO:0008217;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;circulatory system process#GO:0003013;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;primary metabolic process#GO:0044238;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;regulation of systemic arterial blood pressure#GO:0003073;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;regulation of biological quality#GO:0065008;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000000667.1|UniProtKB=W5LX83 W5LX83 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001597.1|UniProtKB=W5M0D8 W5M0D8 PTHR11903:SF8 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G_H SYNTHASE 2 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;unsaturated fatty acid biosynthetic process#GO:0006636;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;prostaglandin metabolic process#GO:0006693;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;arachidonate metabolic process#GO:0019369;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281 neuron projection#GO:0043005;cell projection#GO:0042995;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 CCKR signaling map#P06959>COX2#G06998;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cyclooxygenase#P00845;Toll receptor signaling pathway#P00054>Gene trancription#G01550;CCKR signaling map#P06959>COX2#G07292;Endothelin signaling pathway#P00019>COX-2#P00582;CCKR signaling map#P06959>COX2#P07080 LEPOC|Ensembl=ENSLOCG00000002338.1|UniProtKB=W5M2X3 W5M2X3 PTHR25465:SF32 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014826.1|UniProtKB=W5NCA0 W5NCA0 PTHR11835:SF34 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;alcohol metabolic process#GO:0006066;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176;dehydrogenase#PC00092 Leucine biosynthesis#P02749>3-Isopropylmalate dehydrogenase#P03001 LEPOC|Ensembl=ENSLOCG00000000055.1|UniProtKB=W5LVA8 W5LVA8 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002106.1|UniProtKB=W5M233 W5M233 PTHR22799:SF3 TETRANECTIN-RELATED TETRANECTIN animal organ development#GO:0048513;anatomical structure development#GO:0048856;developmental process#GO:0032502;biomineral tissue development#GO:0031214;bone mineralization#GO:0030282;animal gross anatomical part developmental process#GO:0160108;tissue development#GO:0009888;multicellular organismal process#GO:0032501;ossification#GO:0001503 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016699.1|UniProtKB=W5NJ22 W5NJ22 PTHR31353:SF9 FAM98 PROTEIN FAM98A intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000011843.1|UniProtKB=W5N1Q2 W5N1Q2 PTHR24229:SF85 NEUROPEPTIDES RECEPTOR MELANIN CONCENTRATING HORMONE RECEPTOR 2B molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013359.1|UniProtKB=W5N760 W5N760 PTHR12015:SF198 SMALL INDUCIBLE CYTOKINE A INTERLEUKIN-8 molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;response to stress#GO:0006950;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;cellular process#GO:0009987;taxis#GO:0042330;response to chemical#GO:0042221;neutrophil migration#GO:1990266;granulocyte migration#GO:0097530;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;defense response to other organism#GO:0098542;neutrophil chemotaxis#GO:0030593;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to lipopolysaccharide#GO:0032496;response to molecule of bacterial origin#GO:0002237;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;immune response#GO:0006955;cell migration#GO:0016477;response to other organism#GO:0051707;leukocyte migration#GO:0050900;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;response to bacterium#GO:0009617;chemotaxis#GO:0006935;inflammatory response#GO:0006954;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 CCKR signaling map#P06959>IL8#G07296;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856;CCKR signaling map#P06959>IL8#G07001;CCKR signaling map#P06959>IL8#P07136;Interleukin signaling pathway#P00036>Interleukin#P00970 LEPOC|Ensembl=ENSLOCG00000010092.1|UniProtKB=W5MVD8 W5MVD8 PTHR15315:SF106 RING FINGER PROTEIN 41, 151 RING FINGER PROTEIN 151 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 LEPOC|Ensembl=ENSLOCG00000012646.1|UniProtKB=W5N4K5 W5N4K5 PTHR46053:SF1 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF11 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011815.1|UniProtKB=W5N1M4 W5N1M4 PTHR13034:SF2 DYNACTIN P62 SUBUNIT DYNACTIN SUBUNIT 4 intracellular transport#GO:0046907;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000010945.1|UniProtKB=W5MYG8 W5MYG8 PTHR24361:SF414 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Apoptosis signaling pathway#P00006>MEKK1#P00291;T cell activation#P00053>MEKK#P01297;FGF signaling pathway#P00021>MEKK1-5#P00634;Toll receptor signaling pathway#P00054>MEKK1#P01357;Integrin signalling pathway#P00034>ERK#P00907;Angiogenesis#P00005>MEKK1#P00208;Ras Pathway#P04393>MEKK1/4#P04543;EGF receptor signaling pathway#P00018>MEKK1-5#P00553 LEPOC|Ensembl=ENSLOCG00000008051.1|UniProtKB=W5MN18 W5MN18 PTHR18945:SF889 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-10 transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic cation transmembrane transporter activity#GO:0008324 response to external stimulus#GO:0009605;system process#GO:0003008;establishment of localization#GO:0051234;transport#GO:0006810;detection of mechanical stimulus#GO:0050982;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;multicellular organismal process#GO:0032501;response to mechanical stimulus#GO:0009612;detection of stimulus#GO:0051606;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;trans-synaptic signaling#GO:0099537;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;detection of stimulus involved in sensory perception#GO:0050906;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;nervous system process#GO:0050877;signaling#GO:0023052;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628 postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;membrane protein complex#GO:0098796;postsynapse#GO:0098794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000013854.1|UniProtKB=W5N8X8 W5N8X8 PTHR13220:SF11 TIMELESS INTERACTING-RELATED TIMELESS-INTERACTING PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular response to stress#GO:0033554;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA replication#GO:0006275;DNA-templated DNA replication#GO:0006261;regulation of DNA metabolic process#GO:0051052;DNA replication#GO:0006260;regulation of DNA-templated DNA replication#GO:0090329;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA metabolic process#GO:0006259;negative regulation of DNA-templated DNA replication#GO:2000104;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219 replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000012556.1|UniProtKB=W5N4A0 W5N4A0 PTHR22975:SF6 UBIQUITIN SPECIFIC PROTEINASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 53 sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;response to abiotic stimulus#GO:0009628;response to mechanical stimulus#GO:0009612;system process#GO:0003008;response to external stimulus#GO:0009605;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000014917.1|UniProtKB=W5NCL2 W5NCL2 PTHR10127:SF863 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING BONE MORPHOGENETIC PROTEIN 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;regionalization#GO:0003002;multicellular organismal process#GO:0032501;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;metabolic process#GO:0008152;dorsal/ventral pattern formation#GO:0009953;primary metabolic process#GO:0044238;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;pattern specification process#GO:0007389;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000013943.1|UniProtKB=W5N983 W5N983 PTHR46275:SF1 HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 vesicle-mediated transport#GO:0016192;receptor internalization#GO:0031623;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;endosomal transport#GO:0016197;receptor-mediated endocytosis#GO:0006898;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;transport#GO:0006810;endocytic recycling#GO:0032456;endocytosis#GO:0006897;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 LEPOC|Ensembl=ENSLOCG00000003633.1|UniProtKB=W5M7E7 W5M7E7 PTHR35258:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 22 SPERMATOGENESIS-ASSOCIATED PROTEIN 22 regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of reproductive process#GO:2000241 LEPOC|Ensembl=ENSLOCG00000002122.1|UniProtKB=W5M2C5 W5M2C5 PTHR47958:SF216 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;reproductive process#GO:0022414;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000006257.1|UniProtKB=W5MGP6 W5MGP6 PTHR23292:SF28 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LITAF DOMAIN-CONTAINING PROTEIN ISOFORM X1 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;zinc ion binding#GO:0008270;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 side of membrane#GO:0098552;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;vesicle#GO:0031982;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome membrane#GO:0031902;cytoplasmic side of membrane#GO:0098562;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634;lysosomal membrane#GO:0005765 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006531.1|UniProtKB=W5MHN4 W5MHN4 PTHR21705:SF4 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 1B endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;vacuole organization#GO:0007033;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;vacuolar transport#GO:0007034;transport#GO:0006810;lytic vacuole organization#GO:0080171;intracellular transport#GO:0046907;endosomal transport#GO:0016197;endosome organization#GO:0007032;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;early endosome to late endosome transport#GO:0045022;cellular process#GO:0009987;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000011830.1|UniProtKB=W5N1N8 W5N1N8 PTHR45874:SF1 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-A10 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009949.1|UniProtKB=W5MUV9 W5MUV9 PTHR12629:SF5 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 1 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;nucleotide catabolic process#GO:0009166;nucleobase-containing small molecule metabolic process#GO:0055086 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000014072.1|UniProtKB=W5N9N8 W5N9N8 PTHR43918:SF11 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093 LEPOC|Ensembl=ENSLOCG00000011518.1|UniProtKB=W5N0J3 W5N0J3 PTHR12864:SF56 RAN BINDING PROTEIN 9-RELATED RAN-BINDING PROTEIN 9 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014888.1|UniProtKB=W5NCH5 W5NCH5 PTHR47979:SF17 DRAB11-RELATED RAS-RELATED PROTEIN RAB-4B ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001 biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;vesicle-mediated transport#GO:0016192;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of transport#GO:0051049;regulation of localization#GO:0032879;localization#GO:0051179;establishment of localization#GO:0051234;regulation of endocytosis#GO:0030100;transport#GO:0006810 vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;recycling endosome#GO:0055037;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000018335.1|UniProtKB=W5NP77 W5NP77 PTHR24104:SF62 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000006780.1|UniProtKB=W5MII4 W5MII4 PTHR10643:SF2 KINETOCHORE PROTEIN NDC80 KINETOCHORE PROTEIN NDC80 HOMOLOG sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic metaphase chromosome alignment#GO:0007080;mitotic cell cycle#GO:0000278;organelle localization#GO:0051640;nuclear division#GO:0000280;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;organelle fission#GO:0048285;localization#GO:0051179;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047 chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;outer kinetochore#GO:0000940;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000016851.1|UniProtKB=W5NJM1 W5NJM1 PTHR45740:SF4 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP11 glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000001624.1|UniProtKB=W5M0G0 W5M0G0 PTHR24023:SF855 COLLAGEN ALPHA COLLAGEN ALPHA-2(VIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000008366.1|UniProtKB=W5MP51 W5MP51 PTHR33198:SF26 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002176.1|UniProtKB=W5M2C6 W5M2C6 PTHR34828:SF1 TESTIS-EXPRESSED PROTEIN 45 STABILIZER OF AXONEMAL MICROTUBULES 5 LEPOC|Ensembl=ENSLOCG00000005498.1|UniProtKB=W5ME26 W5ME26 PTHR21731:SF1 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1-LIKE SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1-LIKE intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000004564.1|UniProtKB=W5MAQ4 W5MAQ4 PTHR24232:SF100 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 35.1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013144.1|UniProtKB=W5N6E2 W5N6E2 PTHR13364:SF6 DEFECTIVE SPERMATOGENESIS PROTEIN 39 SPERMATOGENESIS-DEFECTIVE PROTEIN 39 HOMOLOG protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010384.1|UniProtKB=W5MWG6 W5MWG6 PTHR24070:SF464 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1B hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of biological process#GO:0048519;regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;regulation of neurotransmitter secretion#GO:0046928;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of neurotransmitter transport#GO:0051588;cellular response to chemical stimulus#GO:0070887;regulation of secretion by cell#GO:1903530;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;regulation of exocytosis#GO:0017157;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;regulation of secretion#GO:0051046;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;negative regulation of cellular process#GO:0048523 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 LEPOC|Ensembl=ENSLOCG00000010697.1|UniProtKB=W5MXJ1 W5MXJ1 PTHR20842:SF0 PROTEASE S51 ALPHA-ASPARTYL DIPEPTIDASE DIPEPTIDASE E serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017091.1|UniProtKB=W5NKG2 W5NKG2 PTHR13935:SF169 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE COMPLEX PROTEIN T5-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008284.1|UniProtKB=W5MNV1 W5MNV1 PTHR44156:SF33 SUPERNUMERARY LIMBS, ISOFORM B-RELATED DYNEIN ASSEMBLY FACTOR WITH WD REPEAT DOMAINS 1 cell projection organization#GO:0030030;determination of left/right symmetry#GO:0007368;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;pattern specification process#GO:0007389;organelle assembly#GO:0070925;determination of bilateral symmetry#GO:0009855;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;regionalization#GO:0003002;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;left/right pattern formation#GO:0060972;developmental process#GO:0032502;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031 LEPOC|Ensembl=ENSLOCG00000017987.1|UniProtKB=W5NN79 W5NN79 PTHR11394:SF148 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR, TYPE 2, MEMBER 202 ISOFORM X1 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008118.1|UniProtKB=W5MNA2 W5MNA2 PTHR23238:SF3 RNA BINDING PROTEIN RNA-BINDING PROTEIN EWS RNA binding#GO:0003723;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018313.1|UniProtKB=W5NP55 W5NP55 PTHR15718:SF7 G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH C-TERMINAL DOMAIN-CONTAINING PROTEIN G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 1 cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000006243.1|UniProtKB=W5MGN2 W5MGN2 PTHR24006:SF644 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000004283.1|UniProtKB=W5M9R8 W5M9R8 PTHR22775:SF31 SORTING NEXIN SORTING NEXIN-19 binding#GO:0005488;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012516.1|UniProtKB=W5N452 W5N452 PTHR22975:SF5 UBIQUITIN SPECIFIC PROTEINASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 54 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017657.1|UniProtKB=W5NMA3 W5NMA3 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004719.1|UniProtKB=W5MB95 W5MB95 PTHR46176:SF2 LD21662P PROTEIN FAM76A organelle lumen#GO:0043233;nuclear speck#GO:0016607;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000002592.1|UniProtKB=W5M3V8 W5M3V8 PTHR13367:SF3 UBIQUITIN THIOESTERASE TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 3 deubiquitinase activity#GO:0101005;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;transferase activity#GO:0016740;cysteine-type deubiquitinase activity#GO:0004843;ubiquitin-like protein peptidase activity#GO:0019783;aminoacyltransferase activity#GO:0016755;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of signaling#GO:0023056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;protein modification by small protein conjugation or removal#GO:0070647;regulation of intracellular signal transduction#GO:1902531;regulation of Wnt signaling pathway#GO:0030111;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of response to external stimulus#GO:0032102;negative regulation of innate immune response#GO:0045824;negative regulation of signal transduction#GO:0009968;positive regulation of Wnt signaling pathway#GO:0030177;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of immune response#GO:0050776;negative regulation of immune response#GO:0050777;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;positive regulation of cell communication#GO:0010647;negative regulation of defense response#GO:0031348;regulation of immune system process#GO:0002682;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;positive regulation of signal transduction#GO:0009967;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of canonical Wnt signaling pathway#GO:0090263;macromolecule metabolic process#GO:0043170;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;post-translational protein modification#GO:0043687;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protease#PC00190;cysteine protease#PC00081 Toll receptor signaling pathway#P00054>A20#P01348 LEPOC|Ensembl=ENSLOCG00000015992.1|UniProtKB=W5NGD6 W5NGD6 PTHR10501:SF61 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B'' snRNA binding#GO:0017069;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 mRNA splicing#P00058>U2#P01478 LEPOC|Ensembl=ENSLOCG00000016504.1|UniProtKB=W5NIC6 W5NIC6 PTHR35072:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 91 COILED-COIL DOMAIN-CONTAINING PROTEIN 91 post-Golgi vesicle-mediated transport#GO:0006892;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;lysosomal transport#GO:0007041;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000014407.1|UniProtKB=W5NAS5 W5NAS5 PTHR45624:SF56 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL CARNITINE_ACYLCARNITINE CARRIER PROTEIN quaternary ammonium group transmembrane transporter activity#GO:0015651;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;intracellular transport#GO:0046907;transport#GO:0006810;mitochondrial transport#GO:0006839;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006840.1|UniProtKB=W5MIR1 W5MIR1 PTHR15571:SF2 GEM-ASSOCIATED PROTEIN 4 GEM-ASSOCIATED PROTEIN 4 mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826 Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;SMN complex#GO:0032797;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000016354.1|UniProtKB=W5NHT5 W5NHT5 PTHR28489:SF5 RENTINAL DEGENERATION 3-LIKE PROTEIN RD3 LEPOC|Ensembl=ENSLOCG00000018183.1|UniProtKB=W5NNS5 W5NNS5 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005683.1|UniProtKB=W5MEQ5 W5MEQ5 PTHR31551:SF1 PRE-MRNA-SPLICING FACTOR CWF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 12 intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000002997.1|UniProtKB=W5M574 W5M574 PTHR14503:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000012037.1|UniProtKB=W5N2E6 W5N2E6 PTHR12429:SF10 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL1B ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 transport#GO:0006810;regulation of response to stimulus#GO:0048583;intracellular protein localization#GO:0008104;import into cell#GO:0098657;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;protein transport#GO:0015031;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;endocytosis#GO:0006897 intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003955.1|UniProtKB=W5M8M3 W5M8M3 PTHR12112:SF9 BNIP - RELATED CAYTAXIN programmed cell death#GO:0012501;cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000004616.1|UniProtKB=W5MAX3 W5MAX3 GPX4 PTHR11592:SF134 GLUTATHIONE PEROXIDASE PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE GPX4 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to oxidative stress#GO:0034599;icosanoid metabolic process#GO:0006690;response to chemical#GO:0042221;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000003824.1|UniProtKB=W5M861 W5M861 PTHR11216:SF123 EH DOMAIN SI:DKEY-98F17.5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015725.1|UniProtKB=W5NFE9 W5NFE9 PTHR24064:SF710 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000010595.1|UniProtKB=W5MX66 W5MX66 PTHR11785:SF323 AMINO ACID TRANSPORTER CYSTINE_GLUTAMATE TRANSPORTER carboxylic acid transmembrane transporter activity#GO:0046943;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007397.1|UniProtKB=W5MKS2 W5MKS2 PTHR16127:SF14 TAXILIN GAMMA-TAXILIN regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of biological process#GO:0050789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000387.1|UniProtKB=W5LWF8 W5LWF8 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000006973.1|UniProtKB=W5MJ79 W5MJ79 PTHR21255:SF64 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 5 binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000013409.1|UniProtKB=W5N7C4 W5N7C4 PTHR23189:SF40 RNA RECOGNITION MOTIF-CONTAINING RNA-BINDING PROTEIN 15B-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004659.1|UniProtKB=W5MB18 W5MB18 PTHR18966:SF351 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 5 transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;sodium ion transmembrane transporter activity#GO:0015081;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;carboxylic acid transmembrane transporter activity#GO:0046943;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324 regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Metabotropic glutamate receptor group I pathway#P00041>GluR5#P01054;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>KA#P01026;Ionotropic glutamate receptor pathway#P00037>KA5#P01000 LEPOC|Ensembl=ENSLOCG00000005281.1|UniProtKB=W5MDC0 W5MDC0 PTHR13817:SF190 TITIN CONTACTIN 4 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000003322.1|UniProtKB=W5M6B7 W5M6B7 PTHR24359:SF0 SERINE/THREONINE-PROTEIN KINASE SBK1 SERINE_THREONINE-PROTEIN KINASE SBK1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016448.1|UniProtKB=W5NI55 W5NI55 PTHR14269:SF60 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED CARDIOLIPIN SYNTHASE (CMP-FORMING) transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780 lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;phospholipid biosynthetic process#GO:0008654;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol biosynthetic process#GO:0006655;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000006715.1|UniProtKB=W5MIA3 W5MIA3 PTHR15598:SF5 ENHANCER OF MRNA-DECAPPING PROTEIN 4 ENHANCER OF MRNA-DECAPPING PROTEIN 4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;molecular condensate scaffold activity#GO:0140693 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA catabolic process#GO:0006401;RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 mRNA capping factor#PC00145 LEPOC|Ensembl=ENSLOCG00000017692.1|UniProtKB=W5NMD8 W5NMD8 PTHR46229:SF2 BOLA TRANSCRIPTION REGULATOR BOLA-LIKE PROTEIN 1 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009093.1|UniProtKB=W5MRS9 W5MRS9 PTHR21964:SF16 BREAST CANCER METASTASIS-SUPPRESSOR 1 BREAST CANCER METASTASIS-SUPPRESSOR 1-LIKE PROTEIN binding#GO:0005488;enzyme binding#GO:0019899;histone deacetylase binding#GO:0042826;protein binding#GO:0005515 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004248.1|UniProtKB=W5M9L7 W5M9L7 PTHR10219:SF97 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN phospholipid transfer activity#GO:0120014;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;molecular carrier activity#GO:0140104;ion binding#GO:0043167;lipid carrier activity#GO:0005319;phospholipid binding#GO:0005543;transporter activity#GO:0005215 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;ceramide transport#GO:0035627;membrane organization#GO:0061024;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000010333.1|UniProtKB=W5MWA8 W5MWA8 PTHR23138:SF190 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789 protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;nuclear export#GO:0051168;protein transport#GO:0015031;protein import into nucleus#GO:0006606;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014448.1|UniProtKB=W5NAY7 W5NAY7 PTHR22950:SF74 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 5 glycine transmembrane transporter activity#GO:0015187;L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171 carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-alpha-amino acid transmembrane transport#GO:1902475;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;localization#GO:0051179;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;glycine transport#GO:0015816 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 LEPOC|Ensembl=ENSLOCG00000005514.1|UniProtKB=W5ME49 W5ME49 PTHR12167:SF5 C-TYPE NATRIURETIC PEPTIDE C-TYPE NATRIURETIC PEPTIDE 3 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000008898.1|UniProtKB=W5MR23 W5MR23 PTHR13094:SF1 NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000018316.1|UniProtKB=W5NP58 W5NP58 PTHR24365:SF522 TOLL-LIKE RECEPTOR TIR DOMAIN-CONTAINING PROTEIN-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;response to stimulus#GO:0050896;signaling#GO:0023052;toll-like receptor signaling pathway#GO:0002224;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003849.1|UniProtKB=W5M884 W5M884 PTHR21577:SF3 SHUGOSHIN SHUGOSHIN 2 cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid cohesion#GO:0007064;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177;meiotic nuclear division#GO:0140013;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;cell cycle#GO:0007049;reproductive process#GO:0022414;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;sister chromatid cohesion#GO:0007062 intracellular membraneless organelle#GO:0043232;cohesin complex#GO:0008278;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793 centromere DNA-binding protein#PC00071 LEPOC|Ensembl=ENSLOCG00000008207.1|UniProtKB=W5MNK7 W5MNK7 PTHR12570:SF1 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MAGNESIUM TRANSPORTER NIPA2 monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;magnesium ion transport#GO:0015693 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000002018.1|UniProtKB=W5M1V8 W5M1V8 PTHR24264:SF20 TRYPSIN-RELATED TRYPSIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001509.1|UniProtKB=W5M011 W5M011 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017927.1|UniProtKB=W5NN21 W5NN21 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002228.1|UniProtKB=W5M2I6 W5M2I6 PTHR11349:SF54 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE C transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550 cellular process#GO:0009987;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;nucleoside triphosphate biosynthetic process#GO:0009142;biosynthetic process#GO:0009058;nucleoside triphosphate metabolic process#GO:0009141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 kinase#PC00137;transferase#PC00220 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 LEPOC|Ensembl=ENSLOCG00000015464.1|UniProtKB=W5NEH1 W5NEH1 PTHR19879:SF6 TRANSCRIPTION INITIATION FACTOR TFIID TAF5-LIKE RNA POLYMERASE II P300_CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 5L structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of DNA-templated transcription#GO:0006355;RNA metabolic process#GO:0016070;regulation of RNA metabolic process#GO:0051252;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;transcription initiation at RNA polymerase II promoter#GO:0006367;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;peptidase complex#GO:1905368;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000014030.1|UniProtKB=W5N9I9 W5N9I9 PTHR23023:SF266 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005793.1|UniProtKB=W5MF39 W5MF39 PTHR47137:SF1 ERMIN ERMIN actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;cellular component organization#GO:0016043;regulation of developmental process#GO:0050793;regulation of cellular component organization#GO:0051128;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;cellular process#GO:0009987;morphogenesis of a branching structure#GO:0001763;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of cell projection organization#GO:0031344;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603 cell cortex#GO:0005938;cell body#GO:0044297;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axon#GO:0030424;intracellular organelle#GO:0043229;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;main axon#GO:0044304;neuron projection#GO:0043005;cell periphery#GO:0071944;intracellular membraneless organelle#GO:0043232;myelin sheath#GO:0043209;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000007350.1|UniProtKB=W5MKJ7 W5MKJ7 PTHR10845:SF43 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 2 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794 cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 CCKR signaling map#P06959>RGS2#P07040;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000004373.1|UniProtKB=W5MA18 W5MA18 PTHR45810:SF17 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010642.1|UniProtKB=W5MXC1 W5MXC1 PTHR35970:SF1 SODIUM CHANNEL AND CLATHRIN LINKER 1 SODIUM CHANNEL AND CLATHRIN LINKER 1 cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007792.1|UniProtKB=W5MM63 W5MM63 PTHR43836:SF1 CATECHOL O-METHYLTRANSFERASE 1-RELATED TRANSMEMBRANE O-METHYLTRANSFERASE O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741 biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;amine metabolic process#GO:0009308;catecholamine metabolic process#GO:0006584;amine catabolic process#GO:0009310;metabolic process#GO:0008152 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000002651.1|UniProtKB=W5M405 W5M405 PTHR46902:SF1 DOMON DOMAIN-CONTAINING PROTEIN FRRS1L DOMON DOMAIN-CONTAINING PROTEIN FRRS1L regulation of biological quality#GO:0065008;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000005049.1|UniProtKB=W5MCG8 W5MCG8 PTHR10605:SF62 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 6 catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010712.1|UniProtKB=W5MXL1 W5MXL1 PTHR11351:SF100 ACYL-COA DESATURASE STEAROYL-COA DESATURASE 5 iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;unsaturated fatty acid biosynthetic process#GO:0006636;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000001407.1|UniProtKB=W5LZP5 W5LZP5 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003155.1|UniProtKB=W5M5R3 W5M5R3 PTHR34707:SF1 VIMENTIN-TYPE INTERMEDIATE FILAMENT-ASSOCIATED COILED-COIL PROTEIN VIMENTIN-TYPE INTERMEDIATE FILAMENT-ASSOCIATED COILED-COIL PROTEIN LEPOC|Ensembl=ENSLOCG00000001446.1|UniProtKB=W5LZU1 W5LZU1 PTHR23411:SF36 TAPASIN IMMUNOGLOBULIN KAPPA CONSTANT immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011351.1|UniProtKB=W5MZZ2 W5MZZ2 PTHR16124:SF3 MIS18-BINDING PROTEIN 1 MIS18-BINDING PROTEIN 1 chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000008250.1|UniProtKB=W5MNQ9 W5MNQ9 PTHR45845:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED PURATROPHIN-1 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000007264.1|UniProtKB=W5MK82 W5MK82 PTHR11276:SF21 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA NUCLEOTIDYLEXOTRANSFERASE DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;DNA-directed DNA polymerase activity#GO:0003887 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000014983.1|UniProtKB=W5NCT6 W5NCT6 PTHR10522:SF0 GONADOLIBERIN PROGONADOLIBERIN-1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>GnRH#P06704 LEPOC|Ensembl=ENSLOCG00000007865.1|UniProtKB=W5MMF8 W5MMF8 PTHR18902:SF24 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED NUCLEAR MITOTIC APPARATUS PROTEIN 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 establishment or maintenance of cell polarity#GO:0007163;organelle localization#GO:0051640;regulation of protein localization#GO:0032880;localization#GO:0051179;spindle localization#GO:0051653;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;regulation of localization#GO:0032879;mitotic cell cycle process#GO:1903047;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;establishment of spindle localization#GO:0051293;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;mitotic spindle pole#GO:0097431;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006760.1|UniProtKB=W5MIJ8 W5MIJ8 PTHR28457:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 CILIARY-ASSOCIATED CALCIUM-BINDING COILED-COIL PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000003919.1|UniProtKB=W5M8I0 W5M8I0 PTHR24418:SF399 TYROSINE-PROTEIN KINASE MEGAKARYOCYTE-ASSOCIATED TYROSINE-PROTEIN KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000016403.1|UniProtKB=W5NHZ8 W5NHZ8 PTHR10183:SF333 CALPAIN CALPAIN-13 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000001078.1|UniProtKB=W5LYK9 W5LYK9 PTHR22878:SF74 DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED STERILE AFFECTING CILIOGENESIS LEPOC|Ensembl=ENSLOCG00000003630.1|UniProtKB=W5M7F7 W5M7F7 PTHR28588:SF1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 5 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 5 membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;chromosome segregation#GO:0007059 cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000012637.1|UniProtKB=W5N4K7 W5N4K7 PTHR23118:SF42 ATP-CITRATE SYNTHASE ATP-CITRATE SYNTHASE acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;organophosphate biosynthetic process#GO:0090407;purine-containing compound metabolic process#GO:0072521;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing compound biosynthetic process#GO:0034654;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;nucleobase-containing compound metabolic process#GO:0006139;lipid biosynthetic process#GO:0008610 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220 Pyruvate metabolism#P02772>Citrate Lyase#P03137 LEPOC|Ensembl=ENSLOCG00000009000.1|UniProtKB=W5MRF4 W5MRF4 PTHR23250:SF3 DYSFERLIN-RELATED FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000007122.1|UniProtKB=W5MJR5 W5MJR5 PTHR44442:SF1 3-KETO-STEROID REDUCTASE 3-KETO-STEROID REDUCTASE_17-BETA-HYDROXYSTEROID DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;hormone metabolic process#GO:0042445;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;hormone biosynthetic process#GO:0042446 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 metabolite interconversion enzyme#PC00262;reductase#PC00198 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 LEPOC|Ensembl=ENSLOCG00000016455.1|UniProtKB=W5NI67 W5NI67 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006714.1|UniProtKB=W5MIA1 W5MIA1 PTHR24072:SF120 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 1 ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 actin filament organization#GO:0007015;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;regulation of biological quality#GO:0065008;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;establishment or maintenance of cell polarity#GO:0007163;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell shape#GO:0008360;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 membrane#GO:0016020;cell periphery#GO:0071944;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000004388.1|UniProtKB=W5MA34 W5MA34 PTHR11545:SF3 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of translation#GO:0017148;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000001210.1|UniProtKB=W5LZ07 W5LZ07 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004870.1|UniProtKB=W5MBU8 W5MBU8 PTHR10961:SF46 PEROXISOMAL SARCOSINE OXIDASE PEROXISOMAL SARCOSINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579 metabolite interconversion enzyme#PC00262;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000002405.1|UniProtKB=W5M366 W5M366 PTHR48105:SF21 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN REDUCTASE 2, MITOCHONDRIAL antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000010222.1|UniProtKB=W5MVW0 W5MVW0 PTHR10257:SF92 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT EPSILON ISOFORM enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000015638.1|UniProtKB=W5NF42 W5NF42 PTHR11352:SF0 PROLIFERATING CELL NUCLEAR ANTIGEN DNA SLIDING CLAMP PCNA enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 DNA-templated DNA replication#GO:0006261;DNA synthesis involved in DNA replication#GO:0090592;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;DNA replication#GO:0006260;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 DNA polymerase processivity factor#PC00015 DNA replication#P00017>PCNA#P00534 LEPOC|Ensembl=ENSLOCG00000017268.1|UniProtKB=W5NL51 W5NL51 PTHR10985:SF88 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;pattern specification process#GO:0007389;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of macromolecule biosynthetic process#GO:0010558 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000014836.1|UniProtKB=W5NCB4 W5NCB4 PTHR14388:SF6 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000089.1|UniProtKB=W5LVE2 W5LVE2 PTHR48017:SF206 OS05G0424000 PROTEIN-RELATED VESICULAR INHIBITORY AMINO ACID TRANSPORTER amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;glycine transmembrane transporter activity#GO:0015187 establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;transport#GO:0006810;carboxylic acid transport#GO:0046942;synaptic vesicle cycle#GO:0099504;amino acid transport#GO:0006865;organic acid transport#GO:0015849;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;cellular localization#GO:0051641;neutral amino acid transport#GO:0015804;localization#GO:0051179;glycine transport#GO:0015816 synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;neuron projection terminus#GO:0044306;dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;somatodendritic compartment#GO:0036477;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000014680.1|UniProtKB=W5NBR5 W5NBR5 PTHR48092:SF13 KNIRPS-RELATED PROTEIN-RELATED ANDROGEN RECEPTOR DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837 gamete generation#GO:0007276;cellular response to endogenous stimulus#GO:0071495;reproductive structure development#GO:0048608;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;hormone-mediated signaling pathway#GO:0009755;positive regulation of metabolic process#GO:0009893;response to lipid#GO:0033993;response to chemical#GO:0042221;response to hormone#GO:0009725;sex differentiation#GO:0007548;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;development of primary sexual characteristics#GO:0045137;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;reproductive system development#GO:0061458;system development#GO:0048731;male gamete generation#GO:0048232;nuclear receptor-mediated signaling pathway#GO:0141193;gonad development#GO:0008406;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of gene expression#GO:0010468;development of primary male sexual characteristics#GO:0046546;male sex differentiation#GO:0046661;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;cellular response to lipid#GO:0071396;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;male gonad development#GO:0008584;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to steroid hormone stimulus#GO:0071383;multicellular organism development#GO:0007275;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;intracellular receptor signaling pathway#GO:0030522;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;response to steroid hormone#GO:0048545;sexual reproduction#GO:0019953;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>AR#P06774 LEPOC|Ensembl=ENSLOCG00000012104.1|UniProtKB=W5N2N7 W5N2N7 PTHR12151:SF4 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER CYTOCHROME C OXIDASE ASSEMBLY FACTOR SCO1 cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000006395.1|UniProtKB=W5MH61 W5MH61 PTHR31428:SF5 RGM DOMAIN FAMILY MEMBER DRAG-1 REPULSIVE GUIDANCE MOLECULE B coreceptor activity#GO:0015026;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000015554.1|UniProtKB=W5NET9 W5NET9 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004224.1|UniProtKB=W5M9I9 W5M9I9 PTHR23098:SF29 AGAP001331-PA-RELATED MYB-RELATED TRANSCRIPTION FACTOR, PARTNER OF PROFILIN ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000011460.1|UniProtKB=W5N0D1 W5N0D1 PTHR42908:SF6 TRANSLATION ELONGATION FACTOR-RELATED 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleic acid binding#GO:0003676;GTPase activity#GO:0003924;snRNA binding#GO:0017069;RNA binding#GO:0003723;hydrolase activity#GO:0016787 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;protein biosynthetic process#GO:0160307;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;translation#GO:0006412;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;translational elongation#GO:0006414;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytosol#GO:0005829;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000016711.1|UniProtKB=W5NJ40 W5NJ40 PTHR43329:SF165 EPOXIDE HYDROLASE BIFUNCTIONAL EPOXIDE HYDROLASE 2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 homeostatic process#GO:0042592;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;cholesterol homeostasis#GO:0042632;dephosphorylation#GO:0016311;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003879.1|UniProtKB=W5M8B9 W5M8B9 PTHR12356:SF3 NUCLEAR MOVEMENT PROTEIN NUDC NUCLEAR MIGRATION PROTEIN NUDC protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012828.1|UniProtKB=W5N575 W5N575 PTHR47133:SF1 TALIN ROD DOMAIN-CONTAINING PROTEIN 1 TALIN ROD DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 LEPOC|Ensembl=ENSLOCG00000005456.1|UniProtKB=W5MDX0 W5MDX0 PTHR46484:SF3 SI:CH211-171H4.5-RELATED SCHWANN CELL MYELIN PROTEIN ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000004728.1|UniProtKB=W5MBA6 W5MBA6 PTHR12403:SF11 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-LIKE PROTEIN cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005002.1|UniProtKB=W5MCB5 W5MCB5 PTHR11662:SF279 SOLUTE CARRIER FAMILY 17 VOLTAGE-GATED PURINE NUCLEOTIDE UNIPORTER SLC17A9 nucleobase-containing compound transport#GO:0015931;localization#GO:0051179;organophosphate ester transport#GO:0015748;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;transport#GO:0006810 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014325.1|UniProtKB=W5NAJ8 W5NAJ8 PTHR11036:SF37 SEMAPHORIN SEMAPHORIN-3B molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102 cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;taxis#GO:0042330;response to chemical#GO:0042221;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;chemotaxis#GO:0006935;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000009880.1|UniProtKB=W5MUP4 W5MUP4 PTHR22754:SF34 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG A ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of macromolecule metabolic process#GO:0060255;small molecule metabolic process#GO:0044281;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;positive regulation of metabolic process#GO:0009893;organophosphate biosynthetic process#GO:0090407;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;organophosphate metabolic process#GO:0019637;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;acyl-CoA metabolic process#GO:0006637;regulation of protein modification process#GO:0031399;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015069.1|UniProtKB=W5ND35 W5ND35 PTHR10822:SF33 GLYPICAN GLYPICAN-4 PRECURSOR regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;regulation of cellular process#GO:0050794;cell migration#GO:0016477;cell motility#GO:0048870;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cell surface#GO:0009986;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015987.1|UniProtKB=W5NGC9 W5NGC9 PTHR24115:SF400 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF16B ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016481.1|UniProtKB=W5NIA0 W5NIA0 PTHR48526:SF2 SPLICING FACTOR 3B SUBUNIT 6 SPLICING FACTOR 3B SUBUNIT 6 LEPOC|Ensembl=ENSLOCG00000017308.1|UniProtKB=W5NLA4 W5NLA4 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183-LIKE-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009127.1|UniProtKB=W5MRW9 W5MRW9 PTHR45618:SF68 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED DICARBOXYLATE CARRIER UCP2 proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;response to stress#GO:0006950;response to temperature stimulus#GO:0009266;multicellular organismal process#GO:0032501;transport#GO:0006810;temperature homeostasis#GO:0001659;intracellular transport#GO:0046907;multicellular organismal-level homeostasis#GO:0048871;establishment of localization#GO:0051234;response to abiotic stimulus#GO:0009628;homeostatic process#GO:0042592;response to stimulus#GO:0050896;mitochondrial transport#GO:0006839;response to cold#GO:0009409;adaptive thermogenesis#GO:1990845;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014838.1|UniProtKB=W5NCB2 W5NCB2 PTHR10390:SF13 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014154.1|UniProtKB=W5N9Y0 W5N9Y0 PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A LEPOC|Ensembl=ENSLOCG00000009955.1|UniProtKB=W5MUW4 W5MUW4 PTHR31134:SF1 TRANSMEMBRANE PROTEIN 128 TRANSMEMBRANE PROTEIN 128 LEPOC|Ensembl=ENSLOCG00000002892.1|UniProtKB=W5M4U0 W5M4U0 PTHR24061:SF504 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR ISOFORM X1-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009310.1|UniProtKB=W5MSL5 W5MSL5 PTHR45655:SF17 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 guanylate cyclase activity#GO:0004383;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824 response to abiotic stimulus#GO:0009628;response to oxygen levels#GO:0070482;response to stimulus#GO:0050896 catalytic complex#GO:1902494;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cyclase#PC00079;guanylate cyclase#PC00114 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581;Gonadotropin-releasing hormone receptor pathway#P06664>GC#P06726 LEPOC|Ensembl=ENSLOCG00000007745.1|UniProtKB=W5MLZ3 W5MLZ3 PTHR11442:SF41 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ZETA heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488;tetrapyrrole binding#GO:0046906 developmental process#GO:0032502;transport#GO:0006810;multicellular organismal-level homeostasis#GO:0048871;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;cellular process#GO:0009987;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;localization#GO:0051179;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;homeostatic process#GO:0042592;cell development#GO:0048468;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 globin#PC00107;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000011047.1|UniProtKB=W5MYW9 W5MYW9 PTHR13018:SF21 PROBABLE MEMBRANE PROTEIN DUF221-RELATED OSMOSENSITIVE CATION CHANNEL TMEM63C monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000015750.1|UniProtKB=W5NFI3 W5NFI3 PTHR32005:SF4 TRANSMEMBRANE PROTEIN 178B-RELATED TRANSMEMBRANE PROTEIN 178A regulation of multicellular organismal process#GO:0051239;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;regulation of cell development#GO:0060284;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of cytosolic calcium ion concentration#GO:0051480;regulation of biological process#GO:0050789;regulation of hemopoiesis#GO:1903706;calcium ion homeostasis#GO:0055074;regulation of myeloid cell differentiation#GO:0045637;inorganic ion homeostasis#GO:0098771 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000002085.1|UniProtKB=W5M225 W5M225 PTHR11469:SF1 GLUCOSE-6-PHOSPHATE ISOMERASE GLUCOSE-6-PHOSPHATE ISOMERASE carbohydrate binding#GO:0030246;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;monosaccharide binding#GO:0048029;catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;small molecule binding#GO:0036094;binding#GO:0005488 carbohydrate biosynthetic process#GO:0016051;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;ADP catabolic process#GO:0046032;pyruvate metabolic process#GO:0006090;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;ATP metabolic process#GO:0046034;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;oxoacid metabolic process#GO:0043436;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;energy derivation by oxidation of organic compounds#GO:0015980;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;glucose 6-phosphate metabolic process#GO:0051156;catabolic process#GO:0009056;purine ribonucleotide catabolic process#GO:0009154;hexose biosynthetic process#GO:0019319;nucleoside diphosphate catabolic process#GO:0009134;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;isomerase#PC00135 Pentose phosphate pathway#P02762>Glucose-P-Isomerase#P03080;Glycolysis#P00024>Phosphoglucose isomerase#P00674 LEPOC|Ensembl=ENSLOCG00000012988.1|UniProtKB=W5N5T6 W5N5T6 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016042.1|UniProtKB=W5NGK0 W5NGK0 PTHR22984:SF34 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017153.1|UniProtKB=W5NKN8 W5NKN8 PTHR12902:SF8 WASP-1 ACTIN-BINDING PROTEIN WASF1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237 cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;actin filament-based process#GO:0030029;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;organelle organization#GO:0006996;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125;cellular component organization or biogenesis#GO:0071840 cell leading edge#GO:0031252;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000008482.1|UniProtKB=W5MPL2 W5MPL2 PTHR13438:SF2 AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008997.1|UniProtKB=W5MRF5 W5MRF5 PTHR12415:SF0 TYROSYL-DNA PHOSPHODIESTERASE 1 TYROSYL-DNA PHOSPHODIESTERASE 1 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;hydrolase activity#GO:0016787;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000003928.1|UniProtKB=W5M8I7 W5M8I7 PTHR24114:SF31 LEUCINE RICH REPEAT FAMILY PROTEIN NLR FAMILY MEMBER X1 LEPOC|Ensembl=ENSLOCG00000009004.1|UniProtKB=W5MRH3 W5MRH3 PTHR12308:SF22 ANOCTAMIN ANOCTAMIN-7 transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;cellular component organization#GO:0016043;plasma membrane organization#GO:0007009;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;lipid transport#GO:0006869;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001010.1|UniProtKB=W5LYD3 W5LYD3 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011191.1|UniProtKB=W5MZE2 W5MZE2 PTHR21027:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000012196.1|UniProtKB=W5N2Z1 W5N2Z1 PTHR12591:SF5 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular process#GO:0009987;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glucose metabolic process#GO:0006006 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000002054.1|UniProtKB=W5M1X4 W5M1X4 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000004279.1|UniProtKB=W5M9Q8 W5M9Q8 PTHR47972:SF43 KINESIN-LIKE PROTEIN KLP-3 KINESIN-LIKE PROTEIN binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 microtubule-based process#GO:0007017;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000006375.1|UniProtKB=W5MH40 W5MH40 PTHR23107:SF2 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN PROTEIN SSXT transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000016686.1|UniProtKB=W5NJ08 W5NJ08 PTHR24034:SF216 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000014604.1|UniProtKB=W5NBG2 W5NBG2 PTHR11249:SF6 GLIAL FACTOR NATURATION FACTOR GLIA MATURATION FACTOR binding#GO:0005488;protein-containing complex binding#GO:0044877 negative regulation of cytoskeleton organization#GO:0051494;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin nucleation#GO:0051125;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013429.1|UniProtKB=W5N7G0 W5N7G0 PTHR32059:SF2 RAB11-BINDING PROTEIN RELCH RAB11-BINDING PROTEIN RELCH transport#GO:0006810;intracellular transport#GO:0046907;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;sterol transport#GO:0015918;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;intracellular sterol transport#GO:0032366;lipid transport#GO:0006869 intracellular organelle#GO:0043229;endosome#GO:0005768;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802 LEPOC|Ensembl=ENSLOCG00000017758.1|UniProtKB=W5NMK3 W5NMK3 PTHR10155:SF11 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;negative regulation of biological process#GO:0048519;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to peptide#GO:1901652;negative regulation of cell communication#GO:0010648;cytokine-mediated signaling pathway#GO:0019221;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;response to chemical#GO:0042221;response to cytokine#GO:0034097;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 LEPOC|Ensembl=ENSLOCG00000012662.1|UniProtKB=W5N4M5 W5N4M5 PTHR24103:SF611 E3 UBIQUITIN-PROTEIN LIGASE TRIM BBOX AND DUF4200 DOMAIN-CONTAINING PROTEIN-RELATED ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001864.1|UniProtKB=W5M1A0 W5M1A0 PTHR46149:SF5 MIP08469P DEXAMETHASONE-INDUCED RAS-RELATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 LEPOC|Ensembl=ENSLOCG00000001955.1|UniProtKB=W5M1K1 W5M1K1 PTHR24233:SF3 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 14 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007967.1|UniProtKB=W5MMS0 W5MMS0 PTHR24117:SF8 AGAP007537-PB BCL-6 COREPRESSOR transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003976.1|UniProtKB=W5M8P6 W5M8P6 PTHR15711:SF62 RAP GTPASE-ACTIVATING PROTEIN GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 G-protein modulator#PC00022;GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1GAP#P00737 LEPOC|Ensembl=ENSLOCG00000016435.1|UniProtKB=W5NI41 W5NI41 PTHR10336:SF36 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4 lipase activity#GO:0016298;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;calcium ion transmembrane transport#GO:0070588;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;metabolic process#GO:0008152;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;establishment of localization#GO:0051234;transport#GO:0006810;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637 phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Metabotropic glutamate receptor group I pathway#P00041>PLC#P01053;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Endothelin signaling pathway#P00019>PLCbeta#P00591;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PLC#P01068;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Wnt signaling pathway#P00057>Phospholipase C#P01443;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874 LEPOC|Ensembl=ENSLOCG00000008381.1|UniProtKB=W5MP76 W5MP76 PTHR47221:SF3 FIBRINOGEN ALPHA CHAIN FIBRINOGEN ALPHA CHAIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;coagulation#GO:0050817;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;positive regulation of cell-cell adhesion#GO:0022409;regulation of response to wounding#GO:1903034;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;gene expression#GO:0010467;protein maturation#GO:0051604;regulation of response to external stimulus#GO:0032101;fibrinolysis#GO:0042730;platelet aggregation#GO:0070527;metabolic process#GO:0008152;negative regulation of response to wounding#GO:1903035;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of wound healing#GO:0061041;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;response to stimulus#GO:0050896;negative regulation of hemostasis#GO:1900047;cell adhesion#GO:0007155;wound healing#GO:0042060;regulation of biological quality#GO:0065008;negative regulation of coagulation#GO:0050819;protein activation cascade#GO:0072376;macromolecule biosynthetic process#GO:0009059;regulation of hemostasis#GO:1900046;positive regulation of cellular process#GO:0048522;response to wounding#GO:0009611;negative regulation of wound healing#GO:0061045;homotypic cell-cell adhesion#GO:0034109;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of cell adhesion#GO:0030155;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of coagulation#GO:0050818;regulation of response to stimulus#GO:0048583;negative regulation of blood coagulation#GO:0030195;regulation of response to stress#GO:0080134;blood coagulation#GO:0007596;macromolecule metabolic process#GO:0043170;platelet activation#GO:0030168;positive regulation of cell adhesion#GO:0045785;hemostasis#GO:0007599;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;blood coagulation, fibrin clot formation#GO:0072378;cell activation#GO:0001775;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 Plasminogen activating cascade#P00050>Fibrin C-terminal truncation#P01258;Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin monomer#P00418;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443;Blood coagulation#P00011>Fibrinogen#P00406 LEPOC|Ensembl=ENSLOCG00000014659.1|UniProtKB=W5NBN3 W5NBN3 PTHR11709:SF233 MULTI-COPPER OXIDASE FERROXIDASE HEPHL1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722;catalytic activity#GO:0003824 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000000128.1|UniProtKB=W5LVJ7 W5LVJ7 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000017556.1|UniProtKB=W5NM02 W5NM02 PTHR24232:SF112 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001254.1|UniProtKB=W5LZ72 W5LZ72 PTHR10662:SF22 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012075.1|UniProtKB=W5N2J7 W5N2J7 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000013133.1|UniProtKB=W5N6B7 W5N6B7 ELOVL2 PTHR11157:SF16 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000014097.1|UniProtKB=W5N9R0 W5N9R0 PTHR31233:SF14 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D HOMOLOG 2 ISOFORM X1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of microtubule-based process#GO:0032886;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;microtubule anchoring#GO:0034453;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000009448.1|UniProtKB=W5MT37 W5MT37 PTHR46510:SF1 BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;positive regulation of DNA metabolic process#GO:0051054;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of chromatin organization#GO:1902275;regulation of RNA metabolic process#GO:0051252;regulation of DNA replication#GO:0006275;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA replication#GO:0045740;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;ISWI-type complex#GO:0031010;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000017844.1|UniProtKB=W5NMT8 W5NMT8 PTHR46648:SF3 HIT FAMILY PROTEIN 1 HIT DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002063.1|UniProtKB=W5M1Y5 W5M1Y5 PTHR24103:SF667 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM69 ISOFORM X1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008570.1|UniProtKB=W5MPX1 W5MPX1 PTHR43521:SF9 ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;nucleus#GO:0005634;cytosol#GO:0005829;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000006108.1|UniProtKB=W5MG72 W5MG72 PTHR24412:SF428 KELCH PROTEIN KELCH-LIKE PROTEIN 6 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013027.1|UniProtKB=W5N5Y8 W5N5Y8 PTHR46331:SF2 VALACYCLOVIR HYDROLASE SERINE HYDROLASE BPHL catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011985.1|UniProtKB=W5N279 W5N279 PTHR12570:SF13 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MAGNESIUM TRANSPORTER NIPA3 metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transport#GO:0006810;magnesium ion transport#GO:0015693 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000000878.1|UniProtKB=W5LXX6 W5LXX6 PTHR11453:SF127 ANION EXCHANGE PROTEIN SOLUTE CARRIER FAMILY 4 MEMBER 11 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000005850.1|UniProtKB=W5MFA8 W5MFA8 PTHR44535:SF4 PROTEIN CBG16200 SERINE_THREONINE-PROTEIN KINASE NEK8 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 determination of left/right symmetry#GO:0007368;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;system development#GO:0048731;regionalization#GO:0003002;multicellular organismal process#GO:0032501;heart development#GO:0007507;determination of bilateral symmetry#GO:0009855;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;specification of symmetry#GO:0009799;regulation of response to stimulus#GO:0048583;left/right pattern formation#GO:0060972;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000001871.1|UniProtKB=W5M1A6 W5M1A6 PTHR14152:SF5 SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribosome biogenesis#GO:0042254;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000001967.1|UniProtKB=W5M1L8 W5M1L8 PTHR42748:SF7 NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER NMRA-LIKE FAMILY DOMAIN-CONTAINING PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003628.1|UniProtKB=W5M7H1 W5M7H1 PTHR23281:SF23 MERLIN/MOESIN/EZRIN/RADIXIN MERLIN actin binding#GO:0003779;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;integrin binding#GO:0005178 regulation of cell population proliferation#GO:0042127;regulation of nervous system development#GO:0051960;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of neurogenesis#GO:0050767;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of hippo signaling#GO:0035330;negative regulation of biological process#GO:0048519;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of multicellular organismal development#GO:2000026;regulation of anatomical structure morphogenesis#GO:0022603;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;filopodium#GO:0030175;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cell junction#GO:0030054;membraneless organelle#GO:0043228;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000008671.1|UniProtKB=W5MQ92 W5MQ92 PTHR22803:SF65 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED LYMPHOCYTE ANTIGEN 75 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000001393.1|UniProtKB=W5LZN2 W5LZN2 PTHR23168:SF0 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nuclear division#GO:0000280;negative regulation of biological process#GO:0048519;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;negative regulation of sister chromatid segregation#GO:0033046;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;metaphase chromosome alignment#GO:0051310;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;negative regulation of cell cycle#GO:0045786;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic spindle assembly checkpoint signaling#GO:0007094;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;chromosome localization#GO:0050000;negative regulation of chromosome organization#GO:2001251;organelle localization#GO:0051640;cell communication#GO:0007154;localization#GO:0051179;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;mitotic metaphase chromosome alignment#GO:0007080;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cell cycle#GO:0007346;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783 supramolecular complex#GO:0099080;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;membraneless organelle#GO:0043228;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;chromosome#GO:0005694;kinetochore#GO:0000776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003725.1|UniProtKB=W5M7S1 W5M7S1 PTHR45632:SF8 LD33804P KELCH-LIKE PROTEIN 34 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 Cul3-RING ubiquitin ligase complex#GO:0031463;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009834.1|UniProtKB=W5MUG0 W5MUG0 PTHR33488:SF2 ZGC:162509 SUBFAMILY NOT NAMED LEPOC|Ensembl=ENSLOCG00000016692.1|UniProtKB=W5NJ12 W5NJ12 PTHR13490:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN MS35 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013298.1|UniProtKB=W5N6X7 W5N6X7 PTHR24409:SF392 ZINC FINGER PROTEIN 142 BCL6 TRANSCRIPTION REPRESSOR DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000015358.1|UniProtKB=W5NE41 W5NE41 PTHR47978:SF30 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33A pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 metabolic process#GO:0008152;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;catabolic process#GO:0009056;cellular component assembly#GO:0022607;macroautophagy#GO:0016236 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000007220.1|UniProtKB=W5MK28 W5MK28 PTHR11422:SF6 T-CELL SURFACE GLYCOPROTEIN CD4 CD4-2 MOLECULE, TANDEM DUPLICATE 1 PRECURSOR-RELATED immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010554.1|UniProtKB=W5MX24 W5MX24 PTHR15950:SF16 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 3 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000017446.1|UniProtKB=W5NLP2 W5NLP2 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN LOW QUALITY PROTEIN: ODORANT RECEPTOR 125-6-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016154.1|UniProtKB=W5NGZ9 W5NGZ9 PTHR14949:SF32 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 WNT INHIBITORY FACTOR 1 binding#GO:0005488;signaling receptor binding#GO:0005102;receptor serine/threonine kinase binding#GO:0033612;protein binding#GO:0005515 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000006944.1|UniProtKB=W5MJ47 W5MJ47 PTHR15067:SF5 E3 UBIQUITIN-PROTEIN LIGASE RNF8 E3 UBIQUITIN-PROTEIN LIGASE AMFR catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;response to unfolded protein#GO:0006986;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;protein K48-linked ubiquitination#GO:0070936;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013259.1|UniProtKB=W5N6T4 W5N6T4 PTHR11036:SF65 SEMAPHORIN SEMAPHORIN-6D receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000015759.1|UniProtKB=W5NFJ6 W5NFJ6 PTHR10362:SF85 HISTIDINE AMMONIA-LYASE HISTIDINE AMMONIA-LYASE catalytic activity#GO:0003824;lyase activity#GO:0016829 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000004336.1|UniProtKB=W5M9Y1 W5M9Y1 PAN3 PTHR12272:SF11 DEADENYLATION COMPLEX SUBUNIT PAN3 PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3 binding#GO:0005488;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000010813.1|UniProtKB=W5MXZ1 W5MXZ1 PTHR10476:SF1 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 3 macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;late endosome to vacuole transport#GO:0045324;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031 membrane#GO:0016020;vesicle membrane#GO:0012506;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011701.1|UniProtKB=W5N171 W5N171 PTHR11909:SF523 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM EPSILON phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of catabolic process#GO:0009894;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>CK1delta/epsilon#P07089;Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Circadian clock system#P00015>Casein kinase I#P00502;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 LEPOC|Ensembl=ENSLOCG00000010007.1|UniProtKB=W5MV36 W5MV36 PTHR12011:SF469 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E1 ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015184.1|UniProtKB=W5NDH4 W5NDH4 PTHR24045:SF1 FAMILY NOT NAMED N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNITS ALPHA_BETA phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein localization to vacuole#GO:0072665;localization#GO:0051179;protein metabolic process#GO:0019538;vacuole organization#GO:0007033;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;lytic vacuole organization#GO:0080171;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;lysosomal transport#GO:0007041;cellular localization#GO:0051641;protein transport#GO:0015031;protein localization to lysosome#GO:0061462;cellular component organization#GO:0016043;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;carbohydrate derivative biosynthetic process#GO:1901137;organelle organization#GO:0006996;protein targeting to vacuole#GO:0006623;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome organization#GO:0007040 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016989.1|UniProtKB=W5NK42 W5NK42 PTHR45812:SF1 DNA POLYMERASE ZETA CATALYTIC SUBUNIT DNA POLYMERASE ZETA CATALYTIC SUBUNIT DNA-directed DNA polymerase activity#GO:0003887;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985;recombinational repair#GO:0000725;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA synthesis involved in DNA replication#GO:0090592;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001730.1|UniProtKB=W5M0T9 W5M0T9 PTHR11486:SF28 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 9 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;fibroblast growth factor receptor binding#GO:0005104;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000006393.1|UniProtKB=W5MH67 W5MH67 PTHR10218:SF368 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 regulation of membrane potential#GO:0042391;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;G protein-coupled dopamine receptor signaling pathway#GO:0007212;regulation of biological quality#GO:0065008;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;action potential#GO:0001508;regulation of biological process#GO:0050789 cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165 heterotrimeric G-protein#PC00117;G-protein#PC00020 Endothelin signaling pathway#P00019>Gq#P00586;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Alpha adrenergic receptor signaling pathway#P00002>G-Protein#P00077;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;PI3 kinase pathway#P00048>Galpha#P01199;Wnt signaling pathway#P00057>Galpha#P01451;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732 LEPOC|Ensembl=ENSLOCG00000003833.1|UniProtKB=W5M866 W5M866 PTHR13609:SF11 UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED UBIQUITIN DOMAIN-CONTAINING PROTEIN 1 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011205.1|UniProtKB=W5MZF9 W5MZF9 PTHR14949:SF46 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 SCHWANN CELL-SPECIFIC EGF-LIKE REPEAT AUTOCRINE FACTOR protein binding#GO:0005515;receptor serine/threonine kinase binding#GO:0033612;signaling receptor binding#GO:0005102;binding#GO:0005488 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014705.1|UniProtKB=W5NBU3 W5NBU3 PTHR46355:SF1 UPF0428 PROTEIN CXORF56 STING ER EXIT PROTEIN cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular transport#GO:0046907;endoplasmic reticulum membrane organization#GO:0090158;transport#GO:0006810;Golgi vesicle transport#GO:0048193 LEPOC|Ensembl=ENSLOCG00000016951.1|UniProtKB=W5NJZ6 W5NJZ6 PTHR11984:SF9 CONNEXIN GAP JUNCTION ALPHA-10 PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 regulation of biological process#GO:0050789;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;cell communication#GO:0007154 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000006757.1|UniProtKB=W5MIF4 W5MIF4 PTHR21727:SF0 PHOSPHORYLATED CTD INTERACTING FACTOR 1 MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000001378.1|UniProtKB=W5LZK3 W5LZK3 PTHR10225:SF6 HYALURONAN RECEPTOR CD44 ANTIGEN cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;organic acid binding#GO:0043177;anion binding#GO:0043168;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;ion binding#GO:0043167;molecular transducer activity#GO:0060089 positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of MAPK cascade#GO:0043410;defense response#GO:0006952;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>CD44#P00145;Alzheimer disease-presenilin pathway#P00004>CD44 intracellular fragment#P00121;Alzheimer disease-presenilin pathway#P00004>CD44 C-terminal fragment#P00123;Alzheimer disease-presenilin pathway#P00004>CD44 N-terminal fragment#P00174;Alzheimer disease-presenilin pathway#P00004>CD44 transmembrane fragment#P00167 LEPOC|Ensembl=ENSLOCG00000010334.1|UniProtKB=W5MWA1 W5MWA1 PTHR10460:SF26 ABL INTERACTOR FAMILY MEMBER ABL INTERACTOR 2 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell motility#GO:0048870;developmental process#GO:0032502;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular process#GO:0009987;cell migration#GO:0016477;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 actin-based cell projection#GO:0098858;cell leading edge#GO:0031252;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016808.1|UniProtKB=W5NJG6 W5NJG6 PTHR22914:SF47 CHITIN SYNTHASE CHITIN SYNTHASE CHS-1-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;chitin metabolic process#GO:0006030;amino sugar metabolic process#GO:0006040;biosynthetic process#GO:0009058;aminoglycan biosynthetic process#GO:0006023;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000001809.1|UniProtKB=W5M138 W5M138 PTHR46076:SF4 E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RING2 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;chromatin binding#GO:0003682;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013522.1|UniProtKB=W5N7S1 W5N7S1 PTHR13866:SF25 SPARC OSTEONECTIN SPARC-LIKE 1 calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 animal gross anatomical part developmental process#GO:0160108;regulation of synapse organization#GO:0050807;embryonic organ development#GO:0048568;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;ear development#GO:0043583;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;tube morphogenesis#GO:0035239;regulation of cellular component organization#GO:0051128;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;regulation of cellular process#GO:0050794;sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;inner ear morphogenesis#GO:0042472;inner ear development#GO:0048839;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;embryo development#GO:0009790;tube development#GO:0035295 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000010391.1|UniProtKB=W5MWH6 W5MWH6 PTHR23011:SF32 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000002793.1|UniProtKB=W5M4H6 W5M4H6 PTHR12855:SF10 DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;H4 histone acetyltransferase complex#GO:1902562;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008514.1|UniProtKB=W5MPQ4 W5MPQ4 PTHR18945:SF883 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A ISOFORM X1 signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276 establishment of localization#GO:0051234;transport#GO:0006810;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;trans-synaptic signaling#GO:0099537;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000003009.1|UniProtKB=W5M592 W5M592 PTHR12247:SF68 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SCMH1 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006986.1|UniProtKB=W5MJA0 W5MJA0 PTHR48026:SF12 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A3 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000013923.1|UniProtKB=W5N958 W5N958 PTHR47238:SF4 MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012507.1|UniProtKB=W5N440 W5N440 PTHR15301:SF11 INSULIN-INDUCED GENE 1 INSULIN-INDUCED GENE 1 PROTEIN regulation of cell communication#GO:0010646;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;SREBP signaling pathway#GO:0032933;response to peptide hormone#GO:0043434;biosynthetic process#GO:0009058;biological regulation#GO:0065007;lipid biosynthetic process#GO:0008610;negative regulation of response to stimulus#GO:0048585;secondary alcohol biosynthetic process#GO:1902653;regulation of response to stimulus#GO:0048583;cholesterol metabolic process#GO:0008203;cellular response to insulin stimulus#GO:0032869;negative regulation of cellular process#GO:0048523;secondary alcohol metabolic process#GO:1902652;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;cellular localization#GO:0051641;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;cellular response to lipid#GO:0071396;cholesterol biosynthetic process#GO:0006695;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;alcohol metabolic process#GO:0006066;cellular response to peptide hormone stimulus#GO:0071375;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;localization#GO:0051179;regulation of signal transduction#GO:0009966;cellular response to nitrogen compound#GO:1901699;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;regulation of response to stress#GO:0080134;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;response to endogenous stimulus#GO:0009719;regulation of cellular response to stress#GO:0080135;negative regulation of intracellular signal transduction#GO:1902532;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;response to lipid#GO:0033993;response to chemical#GO:0042221;response to stress#GO:0006950;response to hormone#GO:0009725;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000013688.1|UniProtKB=W5N8C5 W5N8C5 PTHR13466:SF2 TEX2 PROTEIN-RELATED TESTIS-EXPRESSED PROTEIN 2 lipid binding#GO:0008289;binding#GO:0005488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000014600.1|UniProtKB=W5NBF7 W5NBF7 PTHR21016:SF7 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 3 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 regulation of response to stimulus#GO:0048583;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of Notch signaling pathway#GO:0045747;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052 LEPOC|Ensembl=ENSLOCG00000001279.1|UniProtKB=W5LZC0 W5LZC0 PTHR24346:SF47 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE SIK2-RELATED protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular signal transduction#GO:0035556;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000015579.1|UniProtKB=W5NEX4 W5NEX4 PTHR10217:SF530 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED DELAYED RECTIFIER POTASSIUM CHANNEL KCNH1 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transport#GO:0006813 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010501.1|UniProtKB=W5MX16 W5MX16 PTHR24254:SF6 PROTHROMBIN CUB DOMAIN-CONTAINING PROTEIN protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006554.1|UniProtKB=W5MHV8 W5MHV8 PTHR24115:SF361 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1A ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;axo-dendritic transport#GO:0008088;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;vesicle-mediated transport#GO:0016192;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cytosolic transport#GO:0016482;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;retrograde axonal transport#GO:0008090;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;axonal transport#GO:0098930;cellular localization#GO:0051641;localization#GO:0051179 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000014918.1|UniProtKB=W5NCK8 W5NCK8 PTHR45963:SF3 RE52028P SORTING NEXIN-12 lipid binding#GO:0008289;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;binding#GO:0005488 intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000005288.1|UniProtKB=W5MDB3 W5MDB3 PTHR13333:SF5 M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;protein insertion into membrane#GO:0051205;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007199.1|UniProtKB=W5MK18 W5MK18 PTHR23176:SF107 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 12 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000011472.1|UniProtKB=W5N0D7 W5N0D7 PTHR12322:SF70 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 1 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;sex differentiation#GO:0007548;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004921.1|UniProtKB=W5MC07 W5MC07 PTHR10546:SF4 SODIUM CHANNEL SUBUNIT BETA-1 AND 3 SODIUM CHANNEL REGULATORY SUBUNIT BETA-3 transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;protein binding#GO:0005515;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772 regulation of membrane potential#GO:0042391;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;cardiac muscle cell action potential involved in contraction#GO:0086002;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;heart process#GO:0003015;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;action potential#GO:0001508;muscle system process#GO:0003012;heart contraction#GO:0060047;system process#GO:0003008;cardiac muscle cell contraction#GO:0086003;establishment of localization#GO:0051234;transport#GO:0006810;muscle contraction#GO:0006936;regulation of system process#GO:0044057;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;actin filament-based movement#GO:0030048;monoatomic cation transport#GO:0006812;localization#GO:0051179;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;regulation of heart contraction#GO:0008016;striated muscle contraction#GO:0006941;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;actin-mediated cell contraction#GO:0070252 sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000017391.1|UniProtKB=W5NLI7 W5NLI7 PTHR24232:SF90 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 5B transmembrane signaling receptor activity#GO:0004888;bioactive lipid receptor activity#GO:0045125;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013387.1|UniProtKB=W5N798 W5N798 PTHR10851:SF0 PYRIDOXINE-5-PHOSPHATE OXIDASE PYRIDOXINE-5'-PHOSPHATE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;oxidase#PC00175 Vitamin B6 metabolism#P02787>Pyridoxamine phosphate oxidase#P03236;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine-5-phosphate oxidase#P03120;Pyridoxal phosphate salvage pathway#P02770>Pyridoxine-5-phosphate oxidase#P03123;Pyridoxal-5-phosphate biosynthesis#P02759>Pyridoxine-5-phosphate oxidase#P03061 LEPOC|Ensembl=ENSLOCG00000005753.1|UniProtKB=W5MEY8 W5MEY8 PTHR12449:SF19 DEATH DOMAIN-CONTAINING PROTEIN NUCLEOLAR PROTEIN 4-LIKE LEPOC|Ensembl=ENSLOCG00000016729.1|UniProtKB=W5NJ63 W5NJ63 PTHR12913:SF1 UNR PROTEIN N-RAS UPSTREAM GENE PROTEIN COLD SHOCK DOMAIN-CONTAINING PROTEIN E1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-RNA adaptor activity#GO:0140517 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000000056.1|UniProtKB=W5LVA9 W5LVA9 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008749.1|UniProtKB=W5MQK8 W5MQK8 PTHR24006:SF954 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 24 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005934.1|UniProtKB=W5MFM5 W5MFM5 PTHR19433:SF111 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 4 response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000018366.1|UniProtKB=W5NPA8 W5NPA8 PTHR46675:SF3 E3 UBIQUITIN-PROTEIN LIGASE RNF182 E3 UBIQUITIN-PROTEIN LIGASE RNF182 LEPOC|Ensembl=ENSLOCG00000008040.1|UniProtKB=W5MN04 W5MN04 PTHR24412:SF511 KELCH PROTEIN KELCH-LIKE PROTEIN 41A-RELATED enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 myofibril#GO:0030016;ubiquitin ligase complex#GO:0000151;supramolecular fiber#GO:0099512;organelle subcompartment#GO:0031984;M band#GO:0031430;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;Cul3-RING ubiquitin ligase complex#GO:0031463;sarcomere#GO:0030017;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;sarcoplasmic reticulum membrane#GO:0033017;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;contractile muscle fiber#GO:0043292;sarcoplasmic reticulum#GO:0016529;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sarcoplasm#GO:0016528;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;A band#GO:0031672;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endomembrane system#GO:0012505;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005513.1|UniProtKB=W5ME47 W5ME47 PTHR16181:SF33 PROTEIN FAM83A-RELATED PROTEIN FAM83H binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;intermediate filament cytoskeleton organization#GO:0045104;response to stimulus#GO:0050896;signaling#GO:0023052;intermediate filament-based process#GO:0045103;localization#GO:0051179;cell communication#GO:0007154;regulation of cell motility#GO:2000145;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;positive regulation of cell migration#GO:0030335;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cell migration#GO:0030334;cellular component organization or biogenesis#GO:0071840;positive regulation of locomotion#GO:0040017;intracellular protein localization#GO:0008104 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016867.1|UniProtKB=W5NJP2 W5NJP2 PTHR12048:SF0 CCAAT-BINDING FACTOR-RELATED CCAAT_ENHANCER-BINDING PROTEIN ZETA nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000001774.1|UniProtKB=W5M104 W5M104 PTHR22765:SF478 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF13 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;biological regulation#GO:0065007;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;regulation of cell cycle#GO:0051726;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001536.1|UniProtKB=W5M046 W5M046 PTHR31171:SF3 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 6 LY6_PLAUR DOMAIN-CONTAINING PROTEIN 6B signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548;neurotransmitter receptor regulator activity#GO:0099602;molecular function regulator activity#GO:0098772 LEPOC|Ensembl=ENSLOCG00000010316.1|UniProtKB=W5MW83 W5MW83 PTHR21210:SF0 TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510 LEPOC|Ensembl=ENSLOCG00000001163.1|UniProtKB=W5LYW3 W5LYW3 PTHR24103:SF573 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM62 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;defense response to other organism#GO:0098542;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;defense response to symbiont#GO:0140546;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of signaling#GO:0023056;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017636.1|UniProtKB=W5NM82 W5NM82 PTHR10489:SF937 CELL ADHESION MOLECULE RELAXIN-3 RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375 response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;locomotion#GO:0040011;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000007721.1|UniProtKB=W5MLW6 W5MLW6 PTHR24412:SF162 KELCH PROTEIN KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016839.1|UniProtKB=W5NJK5 W5NJK5 PTHR19282:SF397 TETRASPANIN TETRASPANIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010922.1|UniProtKB=W5MYD4 W5MYD4 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007143.1|UniProtKB=W5MJT6 W5MJT6 PTHR31463:SF4 MACROPHAGE-EXPRESSED GENE 1 PROTEIN MACROPHAGE-EXPRESSED GENE 1 PROTEIN response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742 LEPOC|Ensembl=ENSLOCG00000001499.1|UniProtKB=W5M021 W5M021 PTHR23151:SF94 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;nucleoside phosphate metabolic process#GO:0006753;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mitochondrion#GO:0005739;oxidoreductase complex#GO:1990204;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 acetyltransferase#PC00038;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016338.1|UniProtKB=W5NHR2 W5NHR2 PTHR10812:SF14 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-BETA DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of apoptotic process#GO:0043066;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of apoptotic process#GO:0042981 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000006229.1|UniProtKB=W5MGL9 W5MGL9 PTHR10288:SF101 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 2 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;regulation of mRNA stability#GO:0043488;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005774.1|UniProtKB=W5MF17 W5MF17 PTHR21502:SF6 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN 1 binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;protein binding#GO:0005515 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000015061.1|UniProtKB=W5ND26 W5ND26 PTHR24070:SF200 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2C hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;intracellular signaling cassette#GO:0141124;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;small GTPase-mediated signal transduction#GO:0007264;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 LEPOC|Ensembl=ENSLOCG00000012631.1|UniProtKB=W5N4I6 W5N4I6 PTHR12400:SF73 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 1 phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;alcohol biosynthetic process#GO:0046165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;glycerophospholipid biosynthetic process#GO:0046474;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000008741.1|UniProtKB=W5MQI6 W5MQI6 PTHR19328:SF32 HEDGEHOG-INTERACTING PROTEIN HHIP-LIKE PROTEIN 1 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013629.1|UniProtKB=W5N852 W5N852 PTHR15683:SF5 SCAFFOLD ATTACHMENT FACTOR B-RELATED SAFB-LIKE TRANSCRIPTION MODULATOR intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015807.1|UniProtKB=W5NFQ0 W5NFQ0 PTHR12290:SF19 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 4 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012356.1|UniProtKB=W5N3J7 W5N3J7 PTHR46724:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9-RELATED ADP RIBOSYLATION FACTOR LIKE GTPASE 10 LEPOC|Ensembl=ENSLOCG00000007542.1|UniProtKB=W5ML92 W5ML92 PTHR11947:SF14 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 1, MITOCHONDRIAL protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010808.1|UniProtKB=W5MXY7 W5MXY7 PTHR15077:SF9 FAS-ASSOCIATING DEATH DOMAIN-CONTAINING PROTEIN FADD FAS-ASSOCIATED DEATH DOMAIN PROTEIN Apoptosis signaling pathway#P00006>FADD#P00327;FAS signaling pathway#P00020>FADD#P00622 LEPOC|Ensembl=ENSLOCG00000003924.1|UniProtKB=W5M8H6 W5M8H6 PTHR12901:SF9 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG B, MITOCHONDRIAL intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000017966.1|UniProtKB=W5NN60 W5NN60 PTHR14790:SF15 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 RMI1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA repair#GO:0006281;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;resolution of meiotic recombination intermediates#GO:0000712;nucleobase-containing compound metabolic process#GO:0006139;sexual reproduction#GO:0019953;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;reproductive process#GO:0022414;homologous recombination#GO:0035825 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;DNA helicase complex#GO:0033202;chromosome#GO:0005694;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000011856.1|UniProtKB=W5N1S0 W5N1S0 PTHR32261:SF7 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 3 monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000003811.1|UniProtKB=W5M840 W5M840 PTHR10796:SF36 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 1 system process#GO:0003008;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;cognition#GO:0050890 plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006180.1|UniProtKB=W5MGF6 W5MGF6 PTHR10780:SF20 MITOCHONDRIAL CARRIER HOMOLOG MITOCHONDRIAL CARRIER HOMOLOG 2 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 protein insertion into membrane#GO:0051205;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;biological regulation#GO:0065007;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of cellular process#GO:0048522;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;intracellular protein localization#GO:0008104;regulation of apoptotic process#GO:0042981;positive regulation of programmed cell death#GO:0043068;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;protein localization to mitochondrion#GO:0070585;regulation of biological process#GO:0050789;cellular localization#GO:0051641;localization#GO:0051179;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 LEPOC|Ensembl=ENSLOCG00000006161.1|UniProtKB=W5MGD1 W5MGD1 PTHR13019:SF18 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG A establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;macromolecule localization#GO:0033036;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;protein transport#GO:0015031;establishment of protein localization to extracellular region#GO:0035592;localization#GO:0051179;protein secretion#GO:0009306;secretion#GO:0046903;establishment of localization#GO:0051234 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000007402.1|UniProtKB=W5MKT5 W5MKT5 PTHR15829:SF15 PROTEIN KINASE PKN/PRK1, EFFECTOR RIPOR FAMILY MEMBER 3 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011483.1|UniProtKB=W5N0F3 W5N0F3 PTHR22765:SF40 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF130 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cell death#GO:0008219;cellular process#GO:0009987;programmed cell death#GO:0012501 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013173.1|UniProtKB=W5N6G8 W5N6G8 PTHR12865:SF6 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-BETA kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;Golgi organization#GO:0007030;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;endosome organization#GO:0007032;organophosphate metabolic process#GO:0019637;organelle organization#GO:0006996;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;endomembrane system organization#GO:0010256;biosynthetic process#GO:0009058 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001405.1|UniProtKB=W5LZR2 W5LZR2 PTHR43381:SF4 TRANSLATION INITIATION FACTOR IF-2-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 5B translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000006015.1|UniProtKB=W5MFV4 W5MFV4 PTHR21072:SF13 GPI TRANSAMIDASE COMPONENT PIG-S GPI-ANCHOR TRANSAMIDASE COMPONENT PIGS metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;GPI anchored protein biosynthesis#GO:0180046;protein maturation#GO:0051604;gene expression#GO:0010467 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;transferase complex#GO:1990234;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;caspase complex#GO:0008303;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000007861.1|UniProtKB=W5MMD3 W5MMD3 PTHR46432:SF1 F-BOX ONLY PROTEIN 42 F-BOX ONLY PROTEIN 42 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000006877.1|UniProtKB=W5MIV7 W5MIV7 PTHR46861:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;tumor necrosis factor binding#GO:0043120;protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;death receptor activity#GO:0005035;transmembrane signaling receptor activity#GO:0004888 inflammatory response#GO:0006954;response to stress#GO:0006950;defense response#GO:0006952;response to stimulus#GO:0050896 signaling receptor complex#GO:0043235;membrane microdomain#GO:0098857;membrane#GO:0016020;membrane raft#GO:0045121;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TNFR1#P00288 LEPOC|Ensembl=ENSLOCG00000009459.1|UniProtKB=W5MT39 W5MT39 PTHR18945:SF52 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 trans-synaptic signaling#GO:0099537;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;metal ion transport#GO:0030001;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ligand-gated ion channel#PC00141 Gonadotropin-releasing hormone receptor pathway#P06664>5-HT3AR#P06833;5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422 LEPOC|Ensembl=ENSLOCG00000006614.1|UniProtKB=W5MHY9 W5MHY9 PTHR15254:SF2 FANCONI ANEMIA GROUP G PROTEIN FAMILY MEMBER FANCONI ANEMIA GROUP G PROTEIN response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950 intracellular organelle#GO:0043229;Fanconi anaemia nuclear complex#GO:0043240;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000015229.1|UniProtKB=W5NDN2 W5NDN2 PTHR45635:SF13 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 3 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000005757.1|UniProtKB=W5MEZ6 W5MEZ6 PTHR11985:SF15 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000007099.1|UniProtKB=W5MJP8 W5MJP8 PTHR11639:SF115 S100 CALCIUM-BINDING PROTEIN SI:CH211-105C13.3 cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000000219.1|UniProtKB=W5LVT7 W5LVT7 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002232.1|UniProtKB=W5M2K8 W5M2K8 PTHR16592:SF8 ASTROTACTIN-1-LIKE ASTROTACTIN-1 developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neuron migration#GO:0001764;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;cell migration#GO:0016477;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cell motility#GO:0048870;cell differentiation#GO:0030154 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000006673.1|UniProtKB=W5MI48 W5MI48 PTHR11009:SF4 DER1-LIKE PROTEIN, DERLIN DERLIN-3 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165;protein metabolic process#GO:0019538;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;catabolic process#GO:0009056;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003427.1|UniProtKB=W5M6Q2 W5M6Q2 PTHR10545:SF69 DIAMINE N-ACETYLTRANSFERASE DIAMINE ACETYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;binding#GO:0005488;small molecule binding#GO:0036094;acyltransferase activity#GO:0016746;ion binding#GO:0043167;N-acetyltransferase activity#GO:0008080;cation binding#GO:0043169 transferase#PC00220;acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000002351.1|UniProtKB=W5M332 W5M332 PTHR24257:SF19 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 2B endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;regulation of platelet activation#GO:0010543;proteolysis#GO:0006508;regulation of platelet aggregation#GO:0090330;protein metabolic process#GO:0019538;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of cell adhesion#GO:0030155;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000011900.1|UniProtKB=W5N1Z9 W5N1Z9 PTHR18905:SF11 NINEIN NINEIN localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;centrosome localization#GO:0051642;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393;microtubule anchoring#GO:0034453;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;mitotic spindle#GO:0072686;cell projection#GO:0042995;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;ciliary transition fiber#GO:0097539;mitotic spindle pole#GO:0097431;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819 PDGF signaling pathway#P00047>GSK3#P01153 LEPOC|Ensembl=ENSLOCG00000003476.1|UniProtKB=W5M6V8 W5M6V8 PTHR24114:SF37 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74B LEPOC|Ensembl=ENSLOCG00000010149.1|UniProtKB=W5MVL5 W5MVL5 PTHR20583:SF1 TRIPLE QXXK/R MOTIF-CONTAINING PROTEIN TRIPLE QXXK_R MOTIF-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011040.1|UniProtKB=W5MYT9 W5MYT9 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016426.1|UniProtKB=W5NI34 W5NI34 PTHR12308:SF21 ANOCTAMIN ANOCTAMIN-6 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;molecular carrier activity#GO:0140104;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;monoatomic cation channel activity#GO:0005261;phospholipid scramblase activity#GO:0017128;ligand-gated monoatomic ion channel activity#GO:0015276;lipid carrier activity#GO:0005319;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;intramembrane lipid carrier activity#GO:0140303 lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;monoatomic anion transport#GO:0006820;cellular component organization#GO:0016043;inorganic anion transport#GO:0015698;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;plasma membrane organization#GO:0007009;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;lipid localization#GO:0010876;phospholipid transport#GO:0015914;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;monoatomic ion transmembrane transport#GO:0034220;lipid transport#GO:0006869;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003540.1|UniProtKB=W5M738 W5M738 PTHR13422:SF13 SIN3-HDAC COMPLEX-ASSOCIATED FACTOR SINHCAFL ANTISENSE LNCRNA regulation of cell motility#GO:2000145;regulation of cell migration#GO:0030334;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000008542.1|UniProtKB=W5MPT4 W5MPT4 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008185.1|UniProtKB=W5MNH8 W5MNH8 PTHR13439:SF1 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 4 lipid homeostasis#GO:0055088;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006505.1|UniProtKB=W5MHK0 W5MHK0 PTHR10344:SF9 THYMIDYLATE KINASE THYMIDYLATE KINASE phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside diphosphate metabolic process#GO:0009132;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;nucleotide kinase#PC00172;kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916 LEPOC|Ensembl=ENSLOCG00000012682.1|UniProtKB=W5N4P6 W5N4P6 PTHR11586:SF51 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;enzyme activator activity#GO:0008047;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cell migration#GO:0016477;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;leukocyte migration#GO:0050900;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein biosynthetic process#GO:0160307;cell motility#GO:0048870;signaling#GO:0023052;immune system process#GO:0002376;translation#GO:0006412;cell communication#GO:0007154;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538 catalytic complex#GO:1902494;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535 translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011629.1|UniProtKB=W5N0Y3 W5N0Y3 PTHR14024:SF25 PERILIPIN PERILIPIN-2 regulation of localization#GO:0032879;lipid storage#GO:0019915;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004384.1|UniProtKB=W5MA27 W5MA27 PTHR20883:SF15 PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002836.1|UniProtKB=W5M4M7 W5M4M7 PTHR24390:SF284 ZINC FINGER PROTEIN EXPRESSED SEQUENCE AI854703 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000007385.1|UniProtKB=W5MKQ1 W5MKQ1 PTHR47958:SF56 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX23-RELATED mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000015620.1|UniProtKB=W5NF22 W5NF22 PTHR11276:SF42 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE BETA catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;DNA-directed DNA polymerase activity#GO:0003887 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000000263.1|UniProtKB=W5LVY6 W5LVY6 PTHR10796:SF60 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 3 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006235.1|UniProtKB=W5MGL8 W5MGL8 PTHR35819:SF1 PICALM INTERACTING MITOTIC REGULATOR PIMREG PROTEIN PIMREG LEPOC|Ensembl=ENSLOCG00000004032.1|UniProtKB=W5M8W0 W5M8W0 PTHR15116:SF15 DNA-BINDING PROTEIN SATB FAMILY MEMBER DNA-BINDING PROTEIN SATB2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002636.1|UniProtKB=W5M3Z1 W5M3Z1 PTHR19300:SF32 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000011948.1|UniProtKB=W5N232 W5N232 PTHR10695:SF46 DEPHOSPHO-COA KINASE-RELATED DEPHOSPHO-COA KINASE DOMAIN-CONTAINING PROTEIN kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886;Coenzyme A biosynthesis#P02736>Dephospho-CoA kinase#P02884 LEPOC|Ensembl=ENSLOCG00000004495.1|UniProtKB=W5MAG6 W5MAG6 PTHR10182:SF11 CALCIUM-BINDING PROTEIN 39-RELATED CALCIUM-BINDING PROTEIN 39 kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 LEPOC|Ensembl=ENSLOCG00000018351.1|UniProtKB=W5NP93 W5NP93 PTHR23349:SF63 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FER3-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000004577.1|UniProtKB=W5MAS1 W5MAS1 PTHR24240:SF189 OPSIN TELEOST MULTIPLE TISSUE OPSIN A transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 biological regulation#GO:0065007;detection of stimulus#GO:0051606;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;signal transduction#GO:0007165;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017321.1|UniProtKB=W5NLB7 W5NLB7 PTHR15286:SF13 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 10 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013964.1|UniProtKB=W5N9C0 W5N9C0 PTHR22903:SF4 PLEKHH PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 1 LEPOC|Ensembl=ENSLOCG00000014166.1|UniProtKB=W5N9Z9 W5N9Z9 PTHR24416:SF46 TYROSINE-PROTEIN KINASE RECEPTOR MAST_STEM CELL GROWTH FACTOR RECEPTOR KIT transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;immune system process#GO:0002376;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;mononuclear cell differentiation#GO:1903131;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;leukocyte differentiation#GO:0002521;B cell activation#GO:0042113;cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;lymphocyte differentiation#GO:0030098;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;positive regulation of signal transduction#GO:0009967;positive regulation of locomotion#GO:0040017;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;hemopoiesis#GO:0030097;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;cell migration#GO:0016477;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012919.1|UniProtKB=W5N5J9 W5N5J9 PTHR21608:SF6 KINESIN-LIKE PROTEIN CG14535 KINESIN-LIKE PROTEIN KIF26A protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 regulation of neuron migration#GO:2001222;regulation of cell projection organization#GO:0031344;regulation of cell migration#GO:0030334;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell motility#GO:2000145;regulation of biological process#GO:0050789;regulation of neuron projection development#GO:0010975;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of locomotion#GO:0040012;biological regulation#GO:0065007 LEPOC|Ensembl=ENSLOCG00000017542.1|UniProtKB=W5NLY8 W5NLY8 PTHR12611:SF3 PUR-TRANSCRIPTIONAL ACTIVATOR PURINE-RICH ELEMENT-BINDING PROTEIN GAMMA transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000004281.1|UniProtKB=W5M9R0 W5M9R0 PTHR12411:SF917 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L, LIKE-RELATED catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012611.1|UniProtKB=W5N4G9 W5N4G9 PTHR43550:SF3 3-KETODIHYDROSPHINGOSINE REDUCTASE 3-KETODIHYDROSPHINGOSINE REDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000016126.1|UniProtKB=W5NGW4 W5NGW4 PTHR12603:SF0 CCR4-NOT TRANSCRIPTION COMPLEX RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;modification-dependent protein catabolic process#GO:0019941;positive regulation of mRNA catabolic process#GO:0061014;protein metabolic process#GO:0019538;regulation of RNA metabolic process#GO:0051252;RNA decapping#GO:0110154;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;protein catabolic process#GO:0030163;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;CCR4-NOT complex#GO:0030014 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007747.1|UniProtKB=W5MM00 W5MM00 PTHR10201:SF138 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-24 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular component organization#GO:0016043;cellular process#GO:0009987;catabolic process#GO:0009056;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141 LEPOC|Ensembl=ENSLOCG00000010885.1|UniProtKB=W5MY85 W5MY85 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009547.1|UniProtKB=W5MTH8 W5MTH8 PTHR13803:SF42 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24B zinc ion binding#GO:0008270;SNARE binding#GO:0000149;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043 intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle#GO:0030133;cytoplasm#GO:0005737;vesicle coat#GO:0030120;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000011729.1|UniProtKB=W5N1B5 W5N1B5 PTHR24289:SF13 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 17-ALPHA-HYDROXYLASE_17,20 LYASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 regulation of biological quality#GO:0065008;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;hormone biosynthetic process#GO:0042446;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180;cellular process#GO:0009987;regulation of hormone levels#GO:0010817 LEPOC|Ensembl=ENSLOCG00000007314.1|UniProtKB=W5MKE6 W5MKE6 PTHR24240:SF233 OPSIN 5-HYDROXYTRYPTAMINE RECEPTOR 1D ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;detection of stimulus#GO:0051606;signal transduction#GO:0007165;response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to radiation#GO:0071478 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002311.1|UniProtKB=W5M2W3 W5M2W3 PTHR44080:SF1 E3 UBIQUITIN-PROTEIN LIGASE COP1 E3 UBIQUITIN-PROTEIN LIGASE COP1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 P53 pathway feedback loops 1#P04392>Cop-1#P04540;P53 pathway feedback loops 1#P04392>Cop-1#G04683 LEPOC|Ensembl=ENSLOCG00000004303.1|UniProtKB=W5M9T1 W5M9T1 PTHR14614:SF14 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN N-LYSINE METHYLTRANSFERASE METTL21A N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004472.1|UniProtKB=W5MAD8 W5MAD8 PTHR20852:SF45 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968;Glutamine glutamate conversion#P02745>Glutamine synthase#P04483 LEPOC|Ensembl=ENSLOCG00000016873.1|UniProtKB=W5NJP9 W5NJP9 PTHR24340:SF40 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.4 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016288.1|UniProtKB=W5NHI8 W5NHI8 PTHR24179:SF20 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12A enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175 myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;A band#GO:0031672;sarcomere#GO:0030017;membraneless organelle#GO:0043228;I band#GO:0031674;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;Z disc#GO:0030018 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000000834.1|UniProtKB=W5LXS2 W5LXS2 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007321.1|UniProtKB=W5MKG7 W5MKG7 PTHR14791:SF25 BOMB/KIRA PROTEINS PROTEIN WWC3 kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of macromolecule metabolic process#GO:0060255;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006506.1|UniProtKB=W5MHK8 W5MHK8 PTHR24270:SF3 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 8 endocytosis#GO:0006897;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;cellular process#GO:0009987;nervous system development#GO:0007399;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;transport#GO:0006810;developmental process#GO:0032502;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;multicellular organism development#GO:0007275 caveola#GO:0005901;membrane#GO:0016020;membrane raft#GO:0045121;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane microdomain#GO:0098857;plasma membrane raft#GO:0044853 transfer/carrier protein#PC00219;apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000002400.1|UniProtKB=W5M353 W5M353 PTHR15896:SF8 GOLGI PHOSPHOPROTEIN 2/GP73-RELATED GOLGI MEMBRANE PROTEIN 1 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014586.1|UniProtKB=W5NBD9 W5NBD9 PTHR21461:SF52 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000228.1|UniProtKB=W5LVU6 W5LVU6 PTHR12406:SF29 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;transferase activity#GO:0016740;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;triacylglycerol lipase activity#GO:0004806 organelle organization#GO:0006996;lipid catabolic process#GO:0016042;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;neutral lipid metabolic process#GO:0006638;acylglycerol catabolic process#GO:0046464;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;neutral lipid catabolic process#GO:0046461;triglyceride metabolic process#GO:0006641;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;homeostatic process#GO:0042592;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;lipid droplet organization#GO:0034389;triglyceride catabolic process#GO:0019433;glycerolipid catabolic process#GO:0046503 intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular organelle#GO:0043229 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000011663.1|UniProtKB=W5N120 W5N120 PTHR13166:SF7 PROTEIN C6ORF149 LYR MOTIF-CONTAINING PROTEIN 4 iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;sulfurtransferase complex#GO:1990228;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000006020.1|UniProtKB=W5MFW1 W5MFW1 PTHR47195:SF1 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000007039.1|UniProtKB=W5MJG1 W5MJG1 PTHR24086:SF42 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A NR5A5 PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;tissue development#GO:0009888;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000004985.1|UniProtKB=W5MC95 W5MC95 PTHR11686:SF19 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 5 PROENZYME catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;defense response#GO:0006952;sulfur compound catabolic process#GO:0044273;cellular process#GO:0009987;response to stress#GO:0006950;sulfur compound metabolic process#GO:0006790;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;icosanoid metabolic process#GO:0006690;lipid biosynthetic process#GO:0008610;inflammatory response#GO:0006954;glutathione metabolic process#GO:0006749;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010746.1|UniProtKB=W5MXR4 W5MXR4 PTHR11254:SF79 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HECW1 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;biological regulation#GO:0065007;macromolecule catabolic process#GO:0009057;regulation of cell projection organization#GO:0031344;metabolic process#GO:0008152;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule metabolic process#GO:0043170;regulation of plasma membrane bounded cell projection organization#GO:0120035;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of dendrite morphogenesis#GO:0048814;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002295.1|UniProtKB=W5M2T2 W5M2T2 PTHR11430:SF63 LIPOCALIN LOC555483 PROTEIN-RELATED transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000015585.1|UniProtKB=W5NEX8 W5NEX8 PTHR24223:SF19 ATP-BINDING CASSETTE SUB-FAMILY C CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR ligand-gated monoatomic ion channel activity#GO:0015276;polypeptide conformation or assembly isomerase activity#GO:0120544;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;macromolecular conformation isomerase activity#GO:0120543;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;isomerase activity#GO:0016853;gated channel activity#GO:0022836;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;fluid transport#GO:0042044;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;water transport#GO:0006833;localization#GO:0051179 cytosol#GO:0005829;basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000006583.1|UniProtKB=W5MHU5 W5MHU5 PTHR10856:SF23 CORONIN CORONIN-6 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;cell motility#GO:0048870 actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;lamellipodium#GO:0030027;actin filament#GO:0005884;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000011698.1|UniProtKB=W5N166 W5N166 PTHR31921:SF1 PROTEIN DPCD PROTEIN DPCD protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cell projection organization#GO:0031344;regulation of cilium assembly#GO:1902017;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection assembly#GO:0060491;regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000012439.1|UniProtKB=W5N3V6 W5N3V6 PTHR42693:SF42 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE G catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007503.1|UniProtKB=W5ML51 W5ML51 PTHR23324:SF83 SEC14 RELATED PROTEIN SEC14 LIKE LIPID BINDING 2-RELATED cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000017562.1|UniProtKB=W5NM08 W5NM08 PTHR11214:SF87 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 8 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 aminoglycan biosynthetic process#GO:0006023;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000012580.1|UniProtKB=W5N4C9 W5N4C9 PTHR11675:SF63 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;protein binding#GO:0005515;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;binding#GO:0005488;signaling receptor binding#GO:0005102 glycoprotein metabolic process#GO:0009100;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015127.1|UniProtKB=W5NDC3 W5NDC3 PTHR46026:SF2 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;lamellipodium assembly#GO:0030032;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell projection#GO:0042995;cell leading edge#GO:0031252 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000010124.1|UniProtKB=W5MVI0 W5MVI0 PTHR13411:SF7 PLASMINOGEN RECEPTOR (KT) PLASMINOGEN RECEPTOR (KT) positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of proteolysis#GO:0030162;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 LEPOC|Ensembl=ENSLOCG00000014307.1|UniProtKB=W5NAH6 W5NAH6 PTHR11036:SF20 SEMAPHORIN SEMAPHORIN-3G protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;taxis#GO:0042330;response to chemical#GO:0042221;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;locomotion#GO:0040011;chemotaxis#GO:0006935;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000012654.1|UniProtKB=W5N4L6 W5N4L6 MED20 PTHR12465:SF0 UBIQUITIN SPECIFIC PROTEASE HOMOLOG 49 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004868.1|UniProtKB=W5MBU9 W5MBU9 PTHR14881:SF4 LISH DOMAIN-CONTAINING PROTEIN ARMC9 LISH DOMAIN-CONTAINING PROTEIN ARMC9 cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000015770.1|UniProtKB=W5NFL5 W5NFL5 PTHR12563:SF17 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010298.1|UniProtKB=W5MW51 W5MW51 PTHR14715:SF4 FAM124 DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN FAM124A LEPOC|Ensembl=ENSLOCG00000006265.1|UniProtKB=W5MGR0 W5MGR0 PTHR24073:SF128 DRAB5-RELATED RAB-LIKE PROTEIN 3 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000015484.1|UniProtKB=W5NEJ9 W5NEJ9 PTHR46462:SF2 UPSET, ISOFORM A HISTONE READER KMT2E biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Rpd3L-Expanded complex#GO:0070210 LEPOC|Ensembl=ENSLOCG00000007605.1|UniProtKB=W5MLG6 W5MLG6 PTHR47305:SF1 BEN DOMAIN-CONTAINING PROTEIN 2 BEN DOMAIN CONTAINING 2 sexual reproduction#GO:0019953;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reproductive process#GO:0022414;response to stimulus#GO:0050896;DNA damage response#GO:0006974;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015030.1|UniProtKB=W5NCZ3 W5NCZ3 PTHR24340:SF115 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-6.3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000012441.1|UniProtKB=W5N3W0 W5N3W0 PTHR15938:SF0 TBP-1 INTERACTING PROTEIN HOMOLOGOUS-PAIRING PROTEIN 2 HOMOLOG double-stranded DNA binding#GO:0003690;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;nucleobase-containing compound metabolic process#GO:0006139;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;reciprocal homologous recombination#GO:0140527;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reproductive process#GO:0022414;homologous recombination#GO:0035825;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;homologous chromosome pairing at meiosis#GO:0007129;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA metabolism protein#PC00009 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;General transcription regulation#P00023>TBP#P00670;General transcription by RNA polymerase I#P00022>SL1 complex#P00653 LEPOC|Ensembl=ENSLOCG00000009606.1|UniProtKB=W5MTN7 W5MTN7 PTHR46606:SF3 SHOOTIN-1 SHOOTIN-1 neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of neuron migration#GO:2001222;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522 cell leading edge#GO:0031252;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;axonal growth cone#GO:0044295;growth cone#GO:0030426;axon#GO:0030424;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004439.1|UniProtKB=W5MAD1 W5MAD1 PTHR45728:SF1 ACETYL-COA CARBOXYLASE, ISOFORM A ACETYL-COA CARBOXYLASE 2 ligase activity#GO:0016874;catalytic activity#GO:0003824 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000000958.1|UniProtKB=W5LY64 W5LY64 PTHR11242:SF14 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 9C protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 membrane#GO:0016020;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000006129.1|UniProtKB=W5MG94 W5MG94 PTHR14647:SF62 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 4 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000001076.1|UniProtKB=W5LYK2 W5LYK2 PTHR24241:SF74 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ARGININE VASOPRESSIN RECEPTOR 2C G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological quality#GO:0065008;cell communication#GO:0007154;circulatory system process#GO:0003013;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;system process#GO:0003008;regulation of system process#GO:0044057;regulation of anatomical structure size#GO:0090066;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;blood circulation#GO:0008015;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to hormone#GO:0009725 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013022.1|UniProtKB=W5N5Y1 W5N5Y1 PTHR24193:SF76 ANKYRIN REPEAT PROTEIN GA-BINDING PROTEIN SUBUNIT BETA-1 binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006016.1|UniProtKB=W5MFV5 W5MFV5 PTHR26451:SF866 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004635.1|UniProtKB=W5MAZ3 W5MAZ3 PTHR11849:SF31 ETS ETS DOMAIN-CONTAINING TRANSCRIPTION FACTOR ERF transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000017807.1|UniProtKB=W5NMQ2 W5NMQ2 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000014453.1|UniProtKB=W5NAX9 W5NAX9 PTHR10574:SF383 NETRIN/LAMININ-RELATED NETRIN 5 anatomical structure development#GO:0048856;system development#GO:0048731;multicellular organismal process#GO:0032501;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;anatomical structure morphogenesis#GO:0009653;dendrite development#GO:0016358;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000007085.1|UniProtKB=W5MJM0 W5MJM0 PTHR46166:SF1 HOMEOBOX DOMAIN-CONTAINING PROTEIN HOMEOBOX PROTEIN HOX-D8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007265.1|UniProtKB=W5MK83 W5MK83 PTHR12635:SF14 RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER RHO GTPASE-ACTIVATING PROTEIN 6 ISOFORM X1 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000011118.1|UniProtKB=W5MZ50 W5MZ50 PTHR11576:SF15 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198 cell-cell recognition#GO:0009988;cellular developmental process#GO:0048869;developmental process#GO:0032502;sperm-egg recognition#GO:0035036;oogenesis#GO:0048477;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;single fertilization#GO:0007338;multicellular organismal reproductive process#GO:0048609;binding of sperm to zona pellucida#GO:0007339;anatomical structure development#GO:0048856;cell recognition#GO:0008037;sexual reproduction#GO:0019953;cell development#GO:0048468;fertilization#GO:0009566;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell differentiation#GO:0030154;germ cell development#GO:0007281;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010324.1|UniProtKB=W5MW92 W5MW92 PTHR34523:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 138 COILED-COIL DOMAIN-CONTAINING PROTEIN 138 LEPOC|Ensembl=ENSLOCG00000016478.1|UniProtKB=W5NI97 W5NI97 PTHR12422:SF4 GH09096P CYFIP-RELATED RAC1 INTERACTOR A LEPOC|Ensembl=ENSLOCG00000000960.1|UniProtKB=W5LY63 W5LY63 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000009113.1|UniProtKB=W5MRV5 W5MRV5 PTHR12011:SF469 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E1 ISOFORM X1-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003728.1|UniProtKB=W5M7U4 W5M7U4 PTHR15724:SF0 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 26 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 26 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000005728.1|UniProtKB=W5MEW2 W5MEW2 PTHR10005:SF15 SKI ONCOGENE-RELATED SKI ONCOGENE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;negative regulation of BMP signaling pathway#GO:0030514;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of BMP signaling pathway#GO:0030510;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of RNA biosynthetic process#GO:2001141;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000004172.1|UniProtKB=W5M9D8 W5M9D8 PTHR15856:SF27 PHD FINGER PROTEIN 20-RELATED PHD FINGER PROTEIN 20 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 organelle lumen#GO:0043233;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123 LEPOC|Ensembl=ENSLOCG00000013574.1|UniProtKB=W5N7Y5 W5N7Y5 PTHR11699:SF102 ALDEHYDE DEHYDROGENASE-RELATED RETINAL DEHYDROGENASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity#GO:0016491 terpenoid metabolic process#GO:0006721;isoprenoid biosynthetic process#GO:0008299;oxoacid metabolic process#GO:0043436;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;carboxylic acid biosynthetic process#GO:0046394;regulation of hormone levels#GO:0010817;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;diterpenoid biosynthetic process#GO:0016102;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;biological regulation#GO:0065007;biosynthetic process#GO:0009058;aldehyde catabolic process#GO:0046185;hormone metabolic process#GO:0042445;terpenoid biosynthetic process#GO:0016114;lipid biosynthetic process#GO:0008610 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000012515.1|UniProtKB=W5N450 W5N450 PTHR23055:SF30 CALCIUM BINDING PROTEINS KV CHANNEL-INTERACTING PROTEIN 4 molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;metal ion binding#GO:0046872;cation binding#GO:0043169;channel regulator activity#GO:0016247;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transporter regulator activity#GO:0141108;calcium ion binding#GO:0005509;potassium channel regulator activity#GO:0015459 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000008494.1|UniProtKB=W5MPM8 W5MPM8 PTHR46065:SF2 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF3 catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003254.1|UniProtKB=W5M640 W5M640 PTHR21964:SF34 BREAST CANCER METASTASIS-SUPPRESSOR 1 SIN3 HISTONE DEACETYLASE COREPRESSOR COMPLEX COMPONENT SDS3 protein binding#GO:0005515;histone deacetylase binding#GO:0042826;enzyme binding#GO:0019899;binding#GO:0005488 negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 organelle lumen#GO:0043233;chromosome#GO:0005694;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000013922.1|UniProtKB=W5N965 W5N965 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;inorganic anion transport#GO:0015698;organic acid transport#GO:0015849;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;succinate transport#GO:0015744;phosphate ion transport#GO:0006817;carboxylic acid transmembrane transport#GO:1905039;dicarboxylic acid transport#GO:0006835;cellular process#GO:0009987 mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000003292.1|UniProtKB=W5M675 W5M675 PTHR11267:SF214 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX6L sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000002999.1|UniProtKB=W5M578 W5M578 PTHR11097:SF14 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP45 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;snRNA 3'-end processing#GO:0034472;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;maturation of 5.8S rRNA#GO:0000460;negative regulation of metabolic process#GO:0009892;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nuclear mRNA surveillance#GO:0071028;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;rRNA processing#GO:0006364;snRNA metabolic process#GO:0016073;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000001965.1|UniProtKB=W5M1M1 W5M1M1 PTHR24543:SF333 MULTICOPPER OXIDASE-RELATED EGF-LIKE REPEAT AND DISCOIDIN I-LIKE DOMAIN-CONTAINING PROTEIN 3 positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006206.1|UniProtKB=W5MGI8 W5MGI8 PTHR19957:SF83 SYNTAXIN SYNTAXIN-16 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;membrane fusion#GO:0061025;organelle organization#GO:0006996;macromolecule localization#GO:0033036;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000001772.1|UniProtKB=W5M105 W5M105 PTHR23031:SF5 RHOPHILIN RHOPHILIN-2-RELATED regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;regulation of actin filament bundle assembly#GO:0032231;negative regulation of cytoskeleton organization#GO:0051494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000031.1|UniProtKB=W5LV81 W5LV81 PTHR13031:SF0 RIBONUCLEASE P SUBUNIT P30 RIBONUCLEASE P PROTEIN SUBUNIT P30 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;cellular anatomical structure#GO:0110165;nucleolar ribonuclease P complex#GO:0005655;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;endonuclease complex#GO:1905348;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535 RNA metabolism protein#PC00031;endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000015873.1|UniProtKB=W5NFY6 W5NFY6 PTHR10283:SF65 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 1 symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075 transport#GO:0006810;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;sodium ion transport#GO:0006814;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002288.1|UniProtKB=W5M2R9 W5M2R9 PTHR46104:SF1 GENE 9195-RELATED-RELATED GENE 9195-RELATED LEPOC|Ensembl=ENSLOCG00000007154.1|UniProtKB=W5MJV0 W5MJV0 PTHR31909:SF3 CHROMOSOME 20 ORF85 FAMILY MEMBER CILIARY MICROTUBULE INNER PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017298.1|UniProtKB=W5NL94 W5NL94 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013231.1|UniProtKB=W5N6Q2 W5N6Q2 PTHR38537:SF7 JITTERBUG, ISOFORM N FILAMIN-B Integrin signalling pathway#P00034>Filamin#P00914 LEPOC|Ensembl=ENSLOCG00000005647.1|UniProtKB=W5MEL0 W5MEL0 PTHR47061:SF1 LYR MOTIF-CONTAINING PROTEIN 9 LYR MOTIF-CONTAINING PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000015433.1|UniProtKB=W5NEF0 W5NEF0 PTHR46961:SF13 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN DYNEIN HEAVY CHAIN, CYTOPLASMIC-LIKE PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000018302.1|UniProtKB=W5NP44 W5NP44 GPR151 PTHR24230:SF131 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 151 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005608.1|UniProtKB=W5MEF8 W5MEF8 PTHR11346:SF32 GALECTIN GALECTIN-4 carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000017440.1|UniProtKB=W5NLN6 W5NLN6 PTHR24231:SF38 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000021000.1|UniProtKB=P29667 P29667 mt-cyb PTHR19271:SF42 CYTOCHROME B CYTOCHROME B catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324 aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex III#GO:0045275;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000009060.1|UniProtKB=W5MRN5 W5MRN5 PTHR11412:SF81 MACROGLOBULIN / COMPLEMENT COMPLEMENT C3 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125 regulation of immune response#GO:0050776;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;humoral immune response#GO:0006959;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;positive regulation of response to stimulus#GO:0048584;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;complement activation#GO:0006956;immune response#GO:0006955;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000018326.1|UniProtKB=W5NP68 W5NP68 PTHR24369:SF221 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004548.1|UniProtKB=W5MAM9 W5MAM9 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000014180.1|UniProtKB=W5NA06 W5NA06 PTHR16655:SF5 COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT 3-RELATED LEPOC|Ensembl=ENSLOCG00000001519.1|UniProtKB=W5M050 W5M050 PTHR10155:SF1 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to hormone#GO:0009725;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166 membrane protein complex#GO:0098796;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PDGF signaling pathway#P00047>PI3K#P01168;Angiogenesis#P00005>PI3K#P00236;PI3 kinase pathway#P00048>p85#P01202;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;Integrin signalling pathway#P00034>PI3K#P00936;Axon guidance mediated by netrin#P00009>PI3K#P00363;VEGF signaling pathway#P00056>PI3K#P01413;T cell activation#P00053>PI3K#P01322;p53 pathway feedback loops 2#P04398>PI3K#P04661 LEPOC|Ensembl=ENSLOCG00000010839.1|UniProtKB=W5MY26 W5MY26 PTHR23282:SF155 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM AND LDL-RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000005327.1|UniProtKB=W5MDF7 W5MDF7 PTHR11136:SF5 FOLYLPOLYGLUTAMATE SYNTHASE-RELATED FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;biosynthetic process#GO:0009058;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ligase#PC00142 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate synthase#P02958;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 LEPOC|Ensembl=ENSLOCG00000002365.1|UniProtKB=W5M318 W5M318 PTHR31021:SF2 ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 PROTEIN APCDD1 protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007259.1|UniProtKB=W5MK78 W5MK78 PTHR45818:SF2 PROTEIN VAV PROTO-ONCOGENE VAV guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;intracellular signaling cassette#GO:0141124;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;regulation of immune response#GO:0050776;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;cell motility#GO:0048870;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 B cell activation#P00010>vav#P00368;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GEF#P00875;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169 LEPOC|Ensembl=ENSLOCG00000012630.1|UniProtKB=W5N4J1 W5N4J1 PTHR28659:SF3 RETICULON-LIKE PROTEIN RETICULOPHAGY REGULATOR 1 process utilizing autophagic mechanism#GO:0061919;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of neuron apoptotic process#GO:0043523;reticulophagy#GO:0061709;negative regulation of neuron apoptotic process#GO:0043524;negative regulation of programmed cell death#GO:0043069;autophagy#GO:0006914;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;macroautophagy#GO:0016236 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000003420.1|UniProtKB=W5M6P2 W5M6P2 PTHR44154:SF1 QUINONE OXIDOREDUCTASE ZETA-CRYSTALLIN catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;anion binding#GO:0043168;ion binding#GO:0043167;RNA binding#GO:0003723;purine nucleotide binding#GO:0017076;mRNA 3'-UTR binding#GO:0003730;heterocyclic compound binding#GO:1901363;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;mRNA binding#GO:0003729;oxidoreductase activity, acting on NAD(P)H#GO:0016651 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 LEPOC|Ensembl=ENSLOCG00000010068.1|UniProtKB=W5MVA3 W5MVA3 PTHR13809:SF5 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-5-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494 heterotrimeric G-protein#PC00117 Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;GABA-B receptor II signaling#P05731>Ggamma#P05754;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Wnt signaling pathway#P00057>Ggamma#P01465;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974 LEPOC|Ensembl=ENSLOCG00000005623.1|UniProtKB=W5MEH9 W5MEH9 PTHR15601:SF20 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN 2 response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012337.1|UniProtKB=W5N3H9 W5N3H9 PTHR46624:SF3 AGAP002036-PA ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 1 anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266 cellular component organization or biogenesis#GO:0071840;lipid droplet organization#GO:0034389;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;lipid storage#GO:0019915;cellular process#GO:0009987 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002896.1|UniProtKB=W5M4W5 W5M4W5 NAT10 PTHR10925:SF5 N-ACETYLTRANSFERASE 10 RNA CYTIDINE ACETYLTRANSFERASE acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;ribonucleoprotein complex biogenesis#GO:0022613;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000014622.1|UniProtKB=W5NBI6 W5NBI6 PTHR45532:SF4 WD REPEAT-CONTAINING PROTEIN 97 WD REPEAT DOMAIN 87 LEPOC|Ensembl=ENSLOCG00000002447.1|UniProtKB=W5M3C0 W5M3C0 PTHR25465:SF35 B-BOX DOMAIN CONTAINING FINTRIM FAMILY, MEMBER 83 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012313.1|UniProtKB=W5N3D7 W5N3D7 PTHR46725:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 57 COILED-COIL DOMAIN-CONTAINING PROTEIN 57 regulation of cell cycle#GO:0051726;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;centrosome cycle#GO:0007098;regulation of biological process#GO:0050789;protein polymerization#GO:0051258;cell cycle process#GO:0022402;microtubule nucleation#GO:0007020;membraneless organelle assembly#GO:0140694;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;cytoskeleton organization#GO:0007010;positive regulation of cell cycle#GO:0045787;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;microtubule polymerization or depolymerization#GO:0031109;microtubule polymerization#GO:0046785;positive regulation of mitotic cell cycle#GO:0045931;plasma membrane bounded cell projection assembly#GO:0120031 microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;centriolar satellite#GO:0034451;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876 LEPOC|Ensembl=ENSLOCG00000008943.1|UniProtKB=W5MR87 W5MR87 PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP synthase#PC00002;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000014842.1|UniProtKB=W5NCB9 W5NCB9 PTHR22957:SF621 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 2B molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014113.1|UniProtKB=W5N9T3 W5N9T3 PTHR24006:SF714 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 46 cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003421.1|UniProtKB=W5M6N8 W5M6N8 PTHR47027:SF30 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010505.1|UniProtKB=W5MWW7 W5MWW7 PTHR12450:SF14 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 GLYCOSAMINOGLYCAN XYLOSYLKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000004550.1|UniProtKB=W5MAN1 W5MAN1 PTHR15315:SF122 RING FINGER PROTEIN 41, 151 E3 UBIQUITIN-PROTEIN LIGASE NRDP1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum tubular network#GO:0071782;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000001588.1|UniProtKB=W5M0C7 W5M0C7 PTHR11915:SF432 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502 cell periphery#GO:0071944;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;membrane#GO:0016020;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;I band#GO:0031674;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cell junction#GO:0030054;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 LEPOC|Ensembl=ENSLOCG00000009766.1|UniProtKB=W5MU75 W5MU75 PTHR10010:SF23 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;phosphate transmembrane transporter activity#GO:0005315;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 homeostatic process#GO:0042592;phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;localization#GO:0051179;establishment of localization#GO:0051234;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;chemical homeostasis#GO:0048878 brush border#GO:0005903;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane region#GO:0098590;apical part of cell#GO:0045177;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000004706.1|UniProtKB=W5MB82 W5MB82 PTHR11501:SF15 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 2 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell development#GO:0048468;regulation of microtubule-based movement#GO:0060632;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of microtubule-based process#GO:0032886 microtubule cytoskeleton#GO:0015630;cell body#GO:0044297;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cytoskeleton#GO:0005856;axon#GO:0030424;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000009237.1|UniProtKB=W5MSA6 W5MSA6 PTHR24119:SF0 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;heterocyclic compound binding#GO:1901363;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;lipid binding#GO:0008289;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000009139.1|UniProtKB=W5MRY1 W5MRY1 PTHR24246:SF31 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR G PROTEIN-COUPLED BILE ACID RECEPTOR 1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell surface receptor signaling pathway#GO:0007166;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006073.1|UniProtKB=W5MG26 W5MG26 PTHR12947:SF7 AMSH-LIKE PROTEASE AMSH-LIKE PROTEASE catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 positive regulation of TOR signaling#GO:0032008;localization#GO:0051179;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of signal transduction#GO:0009967;regulation of TORC1 signaling#GO:1903432;establishment of localization#GO:0051234;transport#GO:0006810;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;endosome transport via multivesicular body sorting pathway#GO:0032509;positive regulation of response to stimulus#GO:0048584;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;positive regulation of cellular process#GO:0048522;positive regulation of TORC1 signaling#GO:1904263;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;late endosome to vacuole transport#GO:0045324;regulation of biological process#GO:0050789;endosomal transport#GO:0016197;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000008965.1|UniProtKB=W5MRB3 W5MRB3 PTHR12214:SF2 GC-RICH SEQUENCE DNA-BINDING FACTOR PAX3- AND PAX7-BINDING PROTEIN 1 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005438.1|UniProtKB=W5MDW0 W5MDW0 PTHR23119:SF6 DISCS LARGE DISKS LARGE HOMOLOG 2 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102 protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;cellular process#GO:0009987;nervous system development#GO:0007399;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;receptor clustering#GO:0043113;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;developmental process#GO:0032502;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;protein localization to cell junction#GO:1902414;trans-synaptic signaling#GO:0099537;establishment or maintenance of apical/basal cell polarity#GO:0035088;localization within membrane#GO:0051668;establishment or maintenance of bipolar cell polarity#GO:0061245;localization#GO:0051179;cell communication#GO:0007154;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;anatomical structure development#GO:0048856;system development#GO:0048731;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916 plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054;neuromuscular junction#GO:0031594;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017559.1|UniProtKB=W5NM05 W5NM05 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183-LIKE-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015670.1|UniProtKB=W5NF81 W5NF81 PTHR11931:SF8 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE 2 intramolecular phosphotransferase activity#GO:0016868;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;phosphoglycerate mutase activity#GO:0004619;isomerase activity#GO:0016853 ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ADP catabolic process#GO:0046032;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 mutase#PC00160;isomerase#PC00135 Glycolysis#P00024>Phosphoglyceromutase#P00680 LEPOC|Ensembl=ENSLOCG00000013479.1|UniProtKB=W5N7M6 W5N7M6 PTHR48015:SF11 SERINE/THREONINE-PROTEIN KINASE TAO MISSHAPEN-LIKE KINASE 1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008447.1|UniProtKB=W5MPG7 W5MPG7 PTHR11537:SF90 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNG2 ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;action potential#GO:0001508;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000014625.1|UniProtKB=W5NBI9 W5NBI9 PTHR13612:SF0 ENHANCER OF MRNA-DECAPPING PROTEIN 3 ENHANCER OF MRNA-DECAPPING PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;mRNA binding#GO:0003729;molecular adaptor activity#GO:0060090;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;molecular condensate scaffold activity#GO:0140693 nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;P-body assembly#GO:0033962;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;organelle assembly#GO:0070925;RNA decapping#GO:0110154;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000007777.1|UniProtKB=W5MM41 W5MM41 PTHR45630:SF2 CATION-TRANSPORTING ATPASE-RELATED POLYAMINE-TRANSPORTING ATPASE 13A2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;polyamine transmembrane transporter activity#GO:0015203 intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;membrane fusion#GO:0061025;nitrogen compound transport#GO:0071705;membrane organization#GO:0061024;biological regulation#GO:0065007;macroautophagy#GO:0016236;localization#GO:0051179;vacuole organization#GO:0007033;regulation of mitochondrion organization#GO:0010821;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;vesicle fusion#GO:0006906;metabolic process#GO:0008152;regulation of anatomical structure size#GO:0090066;chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840;intracellular calcium ion homeostasis#GO:0006874;vesicle organization#GO:0016050;organelle organization#GO:0006996;monoatomic ion homeostasis#GO:0050801;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;organelle membrane fusion#GO:0090174;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;process utilizing autophagic mechanism#GO:0061919;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000015363.1|UniProtKB=W5NE49 W5NE49 PTHR16001:SF7 ANGEL WING family ECTO-NOX DISULFIDE-THIOL EXCHANGER 2 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012798.1|UniProtKB=W5N545 W5N545 PTHR46458:SF2 BLR2807 PROTEIN X GLOBIN molecular carrier activity#GO:0140104;small molecule binding#GO:0036094;binding#GO:0005488 response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;response to stimulus#GO:0050896;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;response to hypoxia#GO:0001666 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017655.1|UniProtKB=W5NMA1 W5NMA1 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014772.1|UniProtKB=W5NC30 W5NC30 PTHR31770:SF2 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-1 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000013102.1|UniProtKB=W5N679 W5N679 PTHR10583:SF1 CHROMOGRANIN CHROMOGRANIN-A regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of protein transport#GO:0051223;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;defense response to bacterium#GO:0042742;negative regulation of signaling#GO:0023057;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;regulation of protein localization#GO:0032880;regulation of hormone secretion#GO:0046883;response to stress#GO:0006950;regulation of insulin secretion#GO:0050796;response to biotic stimulus#GO:0009607;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of protein secretion#GO:0050708;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;response to bacterium#GO:0009617;regulation of establishment of protein localization#GO:0070201;regulation of secretion#GO:0051046;response to other organism#GO:0051707;negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;defense response#GO:0006952;response to external stimulus#GO:0009605 intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 CCKR signaling map#P06959>CHGA#G06978;CCKR signaling map#P06959>CHGA#G07271 LEPOC|Ensembl=ENSLOCG00000013483.1|UniProtKB=W5N7M2 W5N7M2 PTHR33689:SF1 FAS-BINDING FACTOR 1 FAS-BINDING FACTOR 1 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000005772.1|UniProtKB=W5MF22 W5MF22 PTHR22594:SF59 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINYL-TRNA SYNTHETASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000011733.1|UniProtKB=W5N1B4 W5N1B4 PTHR24411:SF8 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000006096.1|UniProtKB=W5MG55 W5MG55 PTHR46466:SF1 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000012800.1|UniProtKB=W5N543 W5N543 PTHR11987:SF50 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8F sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;oligosaccharide metabolic process#GO:0009311 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000008440.1|UniProtKB=W5MPF6 W5MPF6 PTHR11733:SF244 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED KELL BLOOD GROUP GLYCOPROTEIN ISOFORM X1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000013458.1|UniProtKB=W5N7I5 W5N7I5 PTHR45965:SF2 INACTIVE RHOMBOID PROTEIN INACTIVE RHOMBOID PROTEIN 2 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of protein secretion#GO:0050708;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;regulation of secretion by cell#GO:1903530;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of secretion#GO:0051046;regulation of signaling#GO:0023051;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000011251.1|UniProtKB=W5MZL4 W5MZL4 PTHR35350:SF1 HYPOTHETICAL LOC314168 DOPAMINE RECEPTOR-INTERACTING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006065.1|UniProtKB=W5MG24 W5MG24 PTHR13140:SF853 MYOSIN UNCONVENTIONAL MYOSIN-VA ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000001146.1|UniProtKB=W5LYU0 W5LYU0 PTHR13618:SF1 LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1 PROTEIN ROGDI HOMOLOG protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000000099.1|UniProtKB=W5LVF3 W5LVF3 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008513.1|UniProtKB=W5MPS8 W5MPS8 PTHR16305:SF28 TESTICULAR SOLUBLE ADENYLYL CYCLASE GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN molecular sensor activity#GO:0140299;adenylate cyclase activity#GO:0004016;molecular function regulator activity#GO:0098772;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;response to chemical#GO:0042221;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of intracellular pH#GO:0051453;response to stimulus#GO:0050896;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AC#P01082;Metabotropic glutamate receptor group III pathway#P00039>AC#P01043 LEPOC|Ensembl=ENSLOCG00000003349.1|UniProtKB=W5M6E7 W5M6E7 PTHR24107:SF2 YNEIN REGULATORY COMPLEX SUBUNIT 5 NLR FAMILY CARD DOMAIN CONTAINING 3 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003871.1|UniProtKB=W5M8A9 W5M8A9 PTHR10351:SF29 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 HOMOLOG 4 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016728.1|UniProtKB=W5NJ61 W5NJ61 PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;small molecule binding#GO:0036094;ion binding#GO:0043167;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169 glycerophospholipid catabolic process#GO:0046475;organophosphate catabolic process#GO:0046434;lipid metabolic process#GO:0006629;glycerolipid catabolic process#GO:0046503;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;cellular process#GO:0009987;lipid catabolic process#GO:0016042;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 LEPOC|Ensembl=ENSLOCG00000012410.1|UniProtKB=W5N3S1 W5N3S1 PTHR12521:SF0 PROTEIN C6ORF130 ADP-RIBOSE GLYCOHYDROLASE OARD1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;purine nucleoside metabolic process#GO:0042278;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;carbohydrate derivative metabolic process#GO:1901135;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521 site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000002061.1|UniProtKB=W5M1Y0 W5M1Y0 PTHR21041:SF3 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN OSTEOCLAST STIMULATORY TRANSMEMBRANE PROTEIN cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;hemopoiesis#GO:0030097;cell development#GO:0048468;reproductive process#GO:0022414;fertilization#GO:0009566;leukocyte differentiation#GO:0002521;single fertilization#GO:0007338;cellular process#GO:0009987;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;osteoclast differentiation#GO:0030316;sexual reproduction#GO:0019953;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000009704.1|UniProtKB=W5MTZ1 W5MTZ1 PTHR11685:SF111 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF19A catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015156.1|UniProtKB=W5NDE3 W5NDE3 PTHR19818:SF141 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013304.1|UniProtKB=W5N6Y7 W5N6Y7 PTHR24229:SF90 NEUROPEPTIDES RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;binding#GO:0005488;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013792.1|UniProtKB=W5N8Q0 W5N8Q0 PTHR22597:SF0 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SUZ12 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;constitutive heterochromatin formation#GO:0140719;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001264.1|UniProtKB=W5LZ73 W5LZ73 PTHR23266:SF420 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007829.1|UniProtKB=W5MM95 W5MM95 PTHR12943:SF7 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UBIQUITIN-LIKE DOMAIN MEMBER 1 PROTEIN transmembrane transporter binding#GO:0044325;binding#GO:0005488;protein binding#GO:0005515 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;monoatomic cation homeostasis#GO:0055080;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;cellular homeostasis#GO:0019725;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;regulation of ERAD pathway#GO:1904292;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;cellular response to topologically incorrect protein#GO:0035967;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;regulation of proteasomal protein catabolic process#GO:0061136;macromolecule catabolic process#GO:0009057;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;negative regulation of biological process#GO:0048519;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;calcium ion homeostasis#GO:0055074;negative regulation of cell communication#GO:0010648;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of signal transduction#GO:0009966;negative regulation of apoptotic process#GO:0043066;intracellular monoatomic cation homeostasis#GO:0030003;regulation of response to stress#GO:0080134;intracellular chemical homeostasis#GO:0055082;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of intrinsic apoptotic signaling pathway#GO:2001242;homeostatic process#GO:0042592;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;regulation of protein catabolic process#GO:0042176;cell communication#GO:0007154;protein metabolic process#GO:0019538;monoatomic ion homeostasis#GO:0050801;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;chemical homeostasis#GO:0048878;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;intracellular calcium ion homeostasis#GO:0006874;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;inorganic ion homeostasis#GO:0098771;regulation of intracellular signal transduction#GO:1902531;regulation of cellular response to stress#GO:0080135;response to unfolded protein#GO:0006986;negative regulation of intracellular signal transduction#GO:1902532 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000000748.1|UniProtKB=W5LXH4 W5LXH4 PTHR45957:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of chromosome segregation#GO:0051983;metaphase/anaphase transition of cell cycle#GO:0044784;regulation of chromosome organization#GO:0033044;metabolic process#GO:0008152;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cell cycle#GO:0007049;protein K11-linked ubiquitination#GO:0070979;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;regulation of cellular component organization#GO:0051128;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;mitotic cell cycle phase transition#GO:0044772;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 Cell cycle#P00013>APC#P00481 LEPOC|Ensembl=ENSLOCG00000014932.1|UniProtKB=W5NCM8 W5NCM8 PTHR47174:SF3 BRIDGING INTEGRATOR 3 BRIDGING INTEGRATOR 3 binding#GO:0005488;lipid binding#GO:0008289 transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;plasma membrane organization#GO:0007009;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;cellular component organization#GO:0016043;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;endocytosis#GO:0006897 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 LEPOC|Ensembl=ENSLOCG00000015080.1|UniProtKB=W5ND52 W5ND52 PTHR12947:SF8 AMSH-LIKE PROTEASE STAM-BINDING PROTEIN ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824 transport#GO:0006810;regulation of response to stimulus#GO:0048583;vacuolar transport#GO:0007034;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;regulation of small GTPase mediated signal transduction#GO:0051056;endosomal transport#GO:0016197;establishment of localization#GO:0051234;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of Ras protein signal transduction#GO:0046578;negative regulation of intracellular signal transduction#GO:1902532;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;late endosome to vacuole transport#GO:0045324;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cleavage furrow#GO:0032154;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cell division site#GO:0032153;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000000430.1|UniProtKB=W5LWG2 W5LWG2 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017790.1|UniProtKB=W5NMN5 W5NMN5 PTHR11984:SF19 CONNEXIN GAP JUNCTION ALPHA-8 PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;localization#GO:0051179;cell communication#GO:0007154;transport#GO:0006810;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;cellular process#GO:0009987;regulation of biological process#GO:0050789 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000004527.1|UniProtKB=W5MAK5 W5MAK5 PTHR24234:SF6 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 5 response to stress#GO:0006950;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010389.1|UniProtKB=W5MWH8 W5MWH8 PTHR21228:SF1 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular process#GO:0009987;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;nucleic acid biosynthetic process#GO:0141187;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000003345.1|UniProtKB=W5M6E0 W5M6E0 PTHR46723:SF1 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000015981.1|UniProtKB=W5NGB8 W5NGB8 PTHR13090:SF1 ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000000408.1|UniProtKB=W5LWE4 W5LWE4 PTHR24416:SF370 TYROSINE-PROTEIN KINASE RECEPTOR HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515 cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular response to nerve growth factor stimulus#GO:1990090;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;signaling receptor complex#GO:0043235;axon#GO:0030424 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005671.1|UniProtKB=W5MEP2 W5MEP2 PTHR10177:SF71 CYCLINS G1_S-SPECIFIC CYCLIN-E1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic cell cycle phase transition#GO:0044772;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789 serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 kinase activator#PC00138 p53 pathway#P00059>Cyclin E#P04610;Cell cycle#P00013>Cyclin E#P00483;Cell cycle#P00013>CdkC#P00489;p53 pathway feedback loops 2#P04398>cyclin E#P04664;Parkinson disease#P00049>Cyclin E#P01213 LEPOC|Ensembl=ENSLOCG00000002143.1|UniProtKB=W5M286 W5M286 PTHR14695:SF7 SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED TESTICULAR SPINDLE-ASSOCIATED PROTEIN SHCBP1L cytokinesis#GO:0000910;nuclear division#GO:0000280;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cytoskeleton-dependent cytokinesis#GO:0061640;multicellular organismal reproductive process#GO:0048609;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;developmental process involved in reproduction#GO:0003006;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;gamete generation#GO:0007276;reproductive process#GO:0022414;meiotic cell cycle#GO:0051321;developmental process#GO:0032502;spermatogenesis#GO:0007283;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;male gamete generation#GO:0048232;male meiotic nuclear division#GO:0007140 spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000015142.1|UniProtKB=W5NDC8 W5NDC8 PTHR48034:SF18 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA-BINDING MOTIF PROTEIN, X CHROMOSOME RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002761.1|UniProtKB=W5M4D8 W5M4D8 PTHR45632:SF4 LD33804P KELCH-LIKE PROTEIN 36 protein binding#GO:0005515;ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003387.1|UniProtKB=W5M6J7 W5M6J7 PTHR13874:SF11 ENDOTHELIN ENDOTHELIN-3 signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of blood pressure#GO:0008217;monoatomic ion homeostasis#GO:0050801;regulation of systemic arterial blood pressure#GO:0003073;positive regulation of biological process#GO:0048518;intracellular chemical homeostasis#GO:0055082;system process#GO:0003008;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;regulation of smooth muscle contraction#GO:0006940;regulation of system process#GO:0044057;regulation of anatomical structure size#GO:0090066;muscle contraction#GO:0006936;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;regulation of muscle system process#GO:0090257;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological process#GO:0050789;muscle system process#GO:0003012;positive regulation of multicellular organismal process#GO:0051240;regulation of biological quality#GO:0065008;regulation of muscle contraction#GO:0006937;calcium ion homeostasis#GO:0055074;circulatory system process#GO:0003013;inorganic ion homeostasis#GO:0098771 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Endothelin signaling pathway#P00019>Big ET1-4#P00574;Endothelin signaling pathway#P00019>ET1-4#P00588 LEPOC|Ensembl=ENSLOCG00000013771.1|UniProtKB=W5N8M0 W5N8M0 PTHR20875:SF6 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6 ISOFORM X1 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000017025.1|UniProtKB=W5NK83 W5NK83 PTHR12027:SF73 WNT RELATED PROTEIN WNT-7B binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;Wnt signaling pathway#GO:0016055;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;regulation of JNK cascade#GO:0046328;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;positive regulation of JNK cascade#GO:0046330;cell fate commitment#GO:0045165;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206 LEPOC|Ensembl=ENSLOCG00000016382.1|UniProtKB=W5NHX2 W5NHX2 PTHR23227:SF87 BUCENTAUR RELATED PROTEIN CFDP2 LEPOC|Ensembl=ENSLOCG00000007074.1|UniProtKB=W5MJK2 W5MJK2 PTHR45771:SF5 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-D4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regionalization#GO:0003002;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;skeletal system development#GO:0001501;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015396.1|UniProtKB=W5NE85 W5NE85 PTHR24351:SF199 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to nitrogen compound#GO:1901698;response to peptide hormone#GO:0043434 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017537.1|UniProtKB=W5NLY3 W5NLY3 PTHR11829:SF405 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D3 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000004698.1|UniProtKB=W5MBA1 W5MBA1 PTHR12905:SF13 METALLOPHOSPHOESTERASE METALLOPHOSPHOESTERASE MPPED2 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010575.1|UniProtKB=W5MX47 W5MX47 PTHR35250:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 4 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 5 LEPOC|Ensembl=ENSLOCG00000005751.1|UniProtKB=W5MEZ1 W5MEZ1 PTHR10698:SF7 V-TYPE PROTON ATPASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT H monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;transmembrane transport#GO:0055085;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;vesicle organization#GO:0016050;vesicle-mediated transport in synapse#GO:0099003;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;monoatomic cation transmembrane transport#GO:0098655;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;monoatomic ion homeostasis#GO:0050801;organelle organization#GO:0006996;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;synaptic vesicle cycle#GO:0099504;developmental process#GO:0032502;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;developmental maturation#GO:0021700 cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;proton-transporting two-sector ATPase complex#GO:0016469;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transporter complex#GO:1990351 ATP synthase#PC00002;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000010102.1|UniProtKB=W5MVF1 W5MVF1 PTHR12121:SF33 CARBON CATABOLITE REPRESSOR PROTEIN 4 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6 hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;CCR4-NOT complex#GO:0030014;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000014845.1|UniProtKB=W5NCC0 W5NCC0 PTHR45691:SF7 PROTEIN DIAPHANOUS FH2 DOMAIN-CONTAINING 2 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006684.1|UniProtKB=W5MI62 W5MI62 PTHR43716:SF5 D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000008274.1|UniProtKB=W5MNV7 W5MNV7 PTHR45920:SF2 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FH1_FH2 DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 positive regulation of organelle organization#GO:0010638;supramolecular fiber organization#GO:0097435;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;positive regulation of actin filament bundle assembly#GO:0032233;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000011778.1|UniProtKB=W5N1H7 W5N1H7 PTHR46209:SF2 PX DOMAIN-CONTAINING PROTEIN SORTING NEXIN-10 binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010987.1|UniProtKB=W5MYQ3 W5MYQ3 PTHR13886:SF2 JNK/SAPK-ASSOCIATED PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4 kinase binding#GO:0019900;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;protein complex scaffold activity#GO:0140378;cytoskeletal protein binding#GO:0008092;MAP kinase scaffold activity#GO:0005078;structural molecule activity#GO:0005198 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016339.1|UniProtKB=W5NHR1 W5NHR1 PTHR19282:SF568 TETRASPANIN TETRASPANIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011303.1|UniProtKB=W5MZT4 W5MZT4 PTHR45673:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED PROTEIN PHOSPHATASE 3 CATALYTIC SUBUNIT ALPHA phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein binding#GO:0005515;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488 intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;calcineurin-mediated signaling#GO:0097720;calcineurin-NFAT signaling cascade#GO:0033173;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein phosphatase#PC00195 B cell activation#P00010>Calcineurin#P00386;Wnt signaling pathway#P00057>Calcineurin#P01446;T cell activation#P00053>Calcineurin#P01315;Gonadotropin-releasing hormone receptor pathway#P06664>Caln#P06728;CCKR signaling map#P06959>CaN#P07178 LEPOC|Ensembl=ENSLOCG00000005072.1|UniProtKB=W5MCK1 W5MCK1 PTHR24343:SF457 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE STK11 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000168.1|UniProtKB=W5LVN0 W5LVN0 PTHR45598:SF5 PROTEIN CBG11839-RELATED 4FE-4S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007269.1|UniProtKB=W5MK88 W5MK88 PTHR46075:SF9 CHIMERIN FAMILY MEMBER CHIMAERIN enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 LEPOC|Ensembl=ENSLOCG00000003363.1|UniProtKB=W5M6G8 W5M6G8 PTHR11042:SF58 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED SERINE_THREONINE-PROTEIN KINASE PDIK1L protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of translational initiation#GO:0006446;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000004265.1|UniProtKB=W5M9P2 W5M9P2 PTHR11941:SF179 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE, MITOCHONDRIAL fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000617.1|UniProtKB=W5LX20 W5LX20 PTHR11661:SF48 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;RNA binding#GO:0003723;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000015449.1|UniProtKB=W5NEF6 W5NEF6 PTHR12019:SF21 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN THYMOPOIETIN A-RELATED peptide hormone#PC00179;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000005421.1|UniProtKB=W5MDT3 W5MDT3 PTHR45686:SF10 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 2 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014471.1|UniProtKB=W5NB11 W5NB11 PTHR10807:SF69 MYOTUBULARIN-RELATED MYOTUBULARIN phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of autophagosome assembly#GO:2000785;phosphate-containing compound metabolic process#GO:0006796;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;glycerolipid metabolic process#GO:0046486;regulation of cellular component organization#GO:0051128;metabolic process#GO:0008152;regulation of macroautophagy#GO:0016241;cellular process#GO:0009987;negative regulation of macroautophagy#GO:0016242;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol dephosphorylation#GO:0046856;organelle localization#GO:0051640;negative regulation of catabolic process#GO:0009895;localization#GO:0051179;dephosphorylation#GO:0016311;phospholipid dephosphorylation#GO:0046839;negative regulation of organelle organization#GO:0010639;primary metabolic process#GO:0044238;negative regulation of cellular component organization#GO:0051129;phospholipid metabolic process#GO:0006644;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;negative regulation of cellular process#GO:0048523;mitochondrion localization#GO:0051646;regulation of catabolic process#GO:0009894;cellular homeostasis#GO:0019725;negative regulation of autophagy#GO:0010507;lipid modification#GO:0030258;regulation of organelle assembly#GO:1902115;regulation of metabolic process#GO:0019222;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000005171.1|UniProtKB=W5MCW9 W5MCW9 PTHR45781:SF4 AGAP000281-PA THYMOCYTE SELECTION-ASSOCIATED HIGH MOBILITY GROUP BOX PROTEIN TOX DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;leukocyte differentiation#GO:0002521;cell development#GO:0048468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;hemopoiesis#GO:0030097;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006223.1|UniProtKB=W5MGK5 W5MGK5 PTHR24082:SF112 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 2 molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000016364.1|UniProtKB=W5NHU6 W5NHU6 PTHR10281:SF120 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED NEUDESIN growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017759.1|UniProtKB=W5NMK4 W5NMK4 PTHR15344:SF14 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 4 enzyme binding#GO:0019899;binding#GO:0005488;small GTPase binding#GO:0031267;protein binding#GO:0005515 regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;positive regulation of cellular component biogenesis#GO:0044089;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;Rho protein signal transduction#GO:0007266;positive regulation of organelle organization#GO:0010638;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of actin polymerization or depolymerization#GO:0008064;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;regulation of cell projection assembly#GO:0060491;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of cell projection organization#GO:0031346 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001535.1|UniProtKB=W5M055 W5M055 PTHR13343:SF15 CREG1 PROTEIN PROTEIN CREG2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000014788.1|UniProtKB=W5NC54 W5NC54 PTHR15976:SF15 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PPAR-GAMMA-LIKE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000007460.1|UniProtKB=W5ML04 W5ML04 PTHR45785:SF2 COMPLEMENT FACTOR H-RELATED COMPLEMENT FACTOR H-RELATED complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000014227.1|UniProtKB=W5NA62 W5NA62 PTHR11769:SF6 HYALURONIDASE HYALURONIDASE-2 catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;glycosaminoglycan catabolic process#GO:0006027 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000010317.1|UniProtKB=W5MW90 W5MW90 PTHR43272:SF117 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 6 ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000002524.1|UniProtKB=W5M3K7 W5M3K7 PTHR46255:SF2 SHORT STATURE HOMEOBOX SHORT STATURE HOMEOBOX PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009070.1|UniProtKB=W5MRP1 W5MRP1 PTHR12064:SF28 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017320.1|UniProtKB=W5NLB6 W5NLB6 PTHR38004:SF1 PROLINE-RICH PROTEIN 33 PROLINE-RICH PROTEIN 33 LEPOC|Ensembl=ENSLOCG00000010908.1|UniProtKB=W5MYB2 W5MYB2 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016197.1|UniProtKB=W5NH57 W5NH57 PTHR11353:SF84 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457 protein folding chaperone complex#GO:0101031;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;chaperonin-containing T-complex#GO:0005832;cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000013523.1|UniProtKB=W5N7R4 W5N7R4 PTHR14952:SF14 ROPPORIN-1-LIKE PROTEIN ROPPORIN-1-LIKE PROTEIN developmental maturation#GO:0021700;male gamete generation#GO:0048232;sperm capacitation#GO:0048240;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;cell maturation#GO:0048469;cellular developmental process#GO:0048869;microtubule-based process#GO:0007017;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;sperm motility#GO:0097722;cilium-dependent cell motility#GO:0060285;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sexual reproduction#GO:0019953;spermatid development#GO:0007286 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009371.1|UniProtKB=W5MSR9 W5MSR9 PTHR11486:SF17 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 12 growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;ion channel regulator activity#GO:0099106;growth factor receptor binding#GO:0070851;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104;transporter regulator activity#GO:0141108;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;channel regulator activity#GO:0016247;protein binding#GO:0005515 regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000017685.1|UniProtKB=W5NMD1 W5NMD1 PTHR40472:SF10 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 5 LEPOC|Ensembl=ENSLOCG00000014902.1|UniProtKB=W5NCJ7 W5NCJ7 PTHR10269:SF18 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;nervous system development#GO:0007399;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014581.1|UniProtKB=W5NBE5 W5NBE5 PTHR11219:SF7 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 system development#GO:0048731;anatomical structure development#GO:0048856;synapse organization#GO:0050808;cell junction organization#GO:0034330;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;axonogenesis#GO:0007409;neuron development#GO:0048666;synaptic membrane adhesion#GO:0099560;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000006203.1|UniProtKB=W5MGI0 W5MGI0 PTHR23267:SF486 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14_DELTA VARIABLE 4 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007804.1|UniProtKB=W5MM62 W5MM62 PTHR12027:SF76 WNT RELATED PROTEIN WNT-10B signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell fate commitment#GO:0045165;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206 LEPOC|Ensembl=ENSLOCG00000012911.1|UniProtKB=W5N5J4 W5N5J4 PTHR14568:SF10 TRANSMEMBRANE SUPERFAMILY 6 MEMBER 1/2 TRANSMEMBRANE 6 SUPERFAMILY MEMBER 1 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852 LEPOC|Ensembl=ENSLOCG00000001659.1|UniProtKB=W5M0K9 W5M0K9 PTHR46297:SF1 ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000008923.1|UniProtKB=W5MR63 W5MR63 PTHR24300:SF326 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2AA1-RELATED binding#GO:0005488;tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000014107.1|UniProtKB=W5N9S6 W5N9S6 PTHR10846:SF77 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 4-RELATED channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;antiporter activity#GO:0015297;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009525.1|UniProtKB=W5MTC7 W5MTC7 PTHR13803:SF43 SEC24-RELATED PROTEIN CIRCULARLY PERMUTATED RAS PROTEIN 1 SNARE binding#GO:0000149;zinc ion binding#GO:0008270;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;COPII-coated vesicle budding#GO:0090114;cellular component organization#GO:0016043 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;cytoplasm#GO:0005737;vesicle coat#GO:0030120;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated membrane#GO:0048475;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000007361.1|UniProtKB=W5MKK8 W5MKK8 PTHR13771:SF9 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 1 ISOFORM X1-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001549.1|UniProtKB=W5M098 W5M098 PTHR12062:SF4 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375 glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009738.1|UniProtKB=W5MU42 W5MU42 PTHR10728:SF32 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 BETA catalytic activity#GO:0003824;phospholipid binding#GO:0005543;hydrolase activity, acting on ester bonds#GO:0016788;small molecule binding#GO:0036094;lipase activity#GO:0016298;ion binding#GO:0043167;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289 phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;organophosphate catabolic process#GO:0046434;glycerolipid catabolic process#GO:0046503;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phospholipase#PC00186 VEGF signaling pathway#P00056>cPLA2#P01409;Angiogenesis#P00005>PLA2#P00227;Oxidative stress response#P00046>cPLA2#P01134;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLA2#P00855;Angiogenesis#P00005>cPLA2#P00251 LEPOC|Ensembl=ENSLOCG00000014656.1|UniProtKB=W5NBM7 W5NBM7 PTHR31594:SF15 AIG1-TYPE G DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012826.1|UniProtKB=W5N580 W5N580 PTHR24027:SF96 CADHERIN-23 CADHERIN-12 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cell migration#GO:0016477;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840 extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;anchoring junction#GO:0070161;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000010725.1|UniProtKB=W5MXN2 W5MXN2 ENOPH1 PTHR20371:SF1 ENOLASE-PHOSPHATASE E1 ENOLASE-PHOSPHATASE E1 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005122.1|UniProtKB=W5MCQ7 W5MCQ7 PTHR10513:SF24 DEOXYNUCLEOSIDE KINASE THYMIDINE KINASE 2, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;deoxynucleoside kinase activity#GO:0019136;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007574.1|UniProtKB=W5MLD3 W5MLD3 PTHR14339:SF11 VASCULIN VASCULIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001602.1|UniProtKB=W5M0D9 W5M0D9 PTHR24339:SF34 HOMEOBOX PROTEIN EMX-RELATED VENTRAL ANTERIOR HOMEOBOX 2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;head development#GO:0060322;nervous system development#GO:0007399;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016489.1|UniProtKB=W5NIB3 W5NIB3 PTHR10127:SF912 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING MEPRIN A SUBUNIT metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000007169.1|UniProtKB=W5MJX8 W5MJX8 PTHR36498:SF1 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 LEPOC|Ensembl=ENSLOCG00000002654.1|UniProtKB=W5M417 W5M417 PTHR10769:SF3 40S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN ES28 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular component assembly#GO:0022607;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618 cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000013501.1|UniProtKB=W5N7P8 W5N7P8 PTHR11937:SF196 ACTIN ACTIN-LIKE PROTEIN 6B chromatin binding#GO:0003682;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 actin and actin related protein#PC00039 LEPOC|Ensembl=ENSLOCG00000004875.1|UniProtKB=W5MBV3 W5MBV3 PTHR11071:SF577 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009208.1|UniProtKB=W5MS70 W5MS70 PTHR12027:SF88 WNT RELATED PROTEIN WNT-3A G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;system development#GO:0048731;cell fate commitment#GO:0045165;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 LEPOC|Ensembl=ENSLOCG00000003437.1|UniProtKB=W5M6R5 W5M6R5 PTHR23245:SF31 TRNA METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3 HOMOLOG tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;carbohydrate derivative metabolic process#GO:1901135;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;carbohydrate derivative biosynthetic process#GO:1901137 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000014210.1|UniProtKB=W5NA44 W5NA44 PTHR24390:SF284 ZINC FINGER PROTEIN EXPRESSED SEQUENCE AI854703 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000009602.1|UniProtKB=W5MTM3 W5MTM3 PTHR12558:SF10 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 23 HOMOLOG enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome segregation#GO:0051983;regulation of chromosome separation#GO:1905818;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;positive regulation of cell cycle process#GO:0090068;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic nuclear division#GO:0007088;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;regulation of mitotic metaphase/anaphase transition#GO:0030071;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell cycle phase transition#GO:1901987;cell division#GO:0051301;modification-dependent protein catabolic process#GO:0019941 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002096.1|UniProtKB=W5M237 W5M237 PTHR10283:SF62 SOLUTE CARRIER FAMILY 13 MEMBER NA(+)_DICARBOXYLATE COTRANSPORTER 3 sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;citrate transmembrane transporter activity#GO:0015137;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;C4-dicarboxylate transmembrane transporter activity#GO:0015556;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;solute:monoatomic cation symporter activity#GO:0015294;succinate transmembrane transporter activity#GO:0015141;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857 dicarboxylic acid transport#GO:0006835;carboxylic acid transmembrane transport#GO:1905039;succinate transport#GO:0015744;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;tricarboxylic acid transport#GO:0006842;organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;carboxylic acid transport#GO:0046942;citrate transport#GO:0015746 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000012721.1|UniProtKB=W5N4U8 W5N4U8 PTHR44313:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017452.1|UniProtKB=W5NLP8 W5NLP8 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN LOW QUALITY PROTEIN: ODORANT RECEPTOR 125-6-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009219.1|UniProtKB=W5MS89 W5MS89 PTHR13238:SF0 PROTEIN C21ORF59 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 298 LEPOC|Ensembl=ENSLOCG00000010997.1|UniProtKB=W5MYN1 W5MYN1 PTHR11548:SF2 THYMIDYLATE SYNTHASE 1 THYMIDYLATE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside monophosphate biosynthetic process#GO:0009124;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Thymidylate synthase#P02954;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>Thymidylate synthase#P02913;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957 LEPOC|Ensembl=ENSLOCG00000008203.1|UniProtKB=W5MNK1 W5MNK1 PTHR31186:SF1 MODULATOR OF SMOOTHENED PROTEIN MODULATOR OF SMOOTHENED PROTEIN negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 endomembrane system#GO:0012505;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;ciliary membrane#GO:0060170;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cell projection membrane#GO:0031253;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006220.1|UniProtKB=W5MGJ9 W5MGJ9 PTHR19433:SF111 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 4 response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005949.1|UniProtKB=W5MFM8 W5MFM8 PTHR14428:SF5 NUCLEOLAR COMPLEX PROTEIN 3 NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG chromatin binding#GO:0003682;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016355.1|UniProtKB=W5NHT6 W5NHT6 PTHR45820:SF1 FI23527P1 PROTON-COUPLED ZINC ANTIPORTER SLC30A1 transporter regulator activity#GO:0141108;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;zinc ion transmembrane transporter activity#GO:0005385;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;ion channel inhibitor activity#GO:0008200;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator activity#GO:0098772;monoatomic ion transmembrane transporter activity#GO:0015075 response to metal ion#GO:0010038;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;cellular process#GO:0009987;detoxification of inorganic compound#GO:0061687;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801;detoxification#GO:0098754;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;response to chemical#GO:0042221;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;response to stimulus#GO:0050896;response to toxic substance#GO:0009636 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000000093.1|UniProtKB=W5LVF1 W5LVF1 PTHR11096:SF0 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE cyclase activity#GO:0009975;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003679.1|UniProtKB=W5M7M0 W5M7M0 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000016134.1|UniProtKB=W5NGX1 W5NGX1 PTHR45704:SF9 RAS-LIKE FAMILY MEMBER 11 RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000010714.1|UniProtKB=W5MXM1 W5MXM1 PTHR13617:SF14 PROTEIN ABHD18 CARDIOLIPIN-SPECIFIC DEACYLASE, MITOCHONDRIAL phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000005356.1|UniProtKB=W5MDJ0 W5MDJ0 PTHR24271:SF97 KALLIKREIN-RELATED MAST CELL PROTEASE 2 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000012512.1|UniProtKB=W5N451 W5N451 PTHR14682:SF1 KATNB1-LIKE PROTEIN 1 KATNB1-LIKE PROTEIN 1 cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000000729.1|UniProtKB=W5LXF1 W5LXF1 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000014734.1|UniProtKB=W5NBY2 W5NBY2 PTHR11461:SF27 SERINE PROTEASE INHIBITOR, SERPIN SERPIN H1 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000015099.1|UniProtKB=W5ND74 W5ND74 PTHR22922:SF5 GPI-ANCHORED PROTEIN P137 CAPRIN-2 signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012041.1|UniProtKB=W5N2F6 W5N2F6 PTHR18911:SF5 CTCL TUMOR ANTIGEN HD-CL-01 COILED-COIL DOMAIN-CONTAINING PROTEIN 186 LEPOC|Ensembl=ENSLOCG00000009100.1|UniProtKB=W5MRT9 W5MRT9 PTHR13713:SF94 SIALYLTRANSFERASE LACTOSYLCERAMIDE ALPHA-2,3-SIALYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007511.1|UniProtKB=W5ML56 W5ML56 PTHR48122:SF1 CENTROMERE PROTEIN H CENTROMERE PROTEIN H binding#GO:0005488 chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;kinetochore#GO:0000776;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775 LEPOC|Ensembl=ENSLOCG00000006152.1|UniProtKB=W5MGC6 W5MGC6 PTHR12268:SF19 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROBREVIN ALPHA plasma membrane#GO:0005886;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001637.1|UniProtKB=W5M0I2 W5M0I2 PTHR47977:SF128 RAS-RELATED PROTEIN RAB LD21953P nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;intracellular transport#GO:0046907;transport#GO:0006810;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000016432.1|UniProtKB=W5NI40 W5NI40 PTHR11417:SF33 SOMATOTROPIN,PROLACTIN PROLACTIN LIKE molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 positive regulation of signaling#GO:0023056;cell communication#GO:0007154;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to nutrient levels#GO:0031667;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000003396.1|UniProtKB=W5M6M0 W5M6M0 PTHR11461:SF50 SERINE PROTEASE INHIBITOR, SERPIN NEUROSERPIN molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000013416.1|UniProtKB=W5N7J5 W5N7J5 PTHR45653:SF4 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 3 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007226.1|UniProtKB=W5MK31 W5MK31 PTHR16516:SF7 AGAP007109-PA PR DOMAIN ZINC FINGER PROTEIN 8 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004848.1|UniProtKB=W5MBR7 W5MBR7 PTHR24089:SF736 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A42 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000017721.1|UniProtKB=W5NMG6 W5NMG6 PTHR45617:SF189 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH ALPHA-2-GLYCOPROTEIN PRECURSOR scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009107.1|UniProtKB=W5MRU9 W5MRU9 PTHR10680:SF14 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 LEPOC|Ensembl=ENSLOCG00000004701.1|UniProtKB=W5MB88 W5MB88 PTHR22804:SF11 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 4 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;system development#GO:0048731;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 extracellular region#GO:0005576;cell junction#GO:0030054;cell periphery#GO:0071944;extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000013136.1|UniProtKB=W5N6B9 W5N6B9 PTHR10252:SF163 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DR1-ASSOCIATED COREPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription#GO:0006351;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000005942.1|UniProtKB=W5MFL9 W5MFL9 PTHR11568:SF2 HEPATOCYTE NUCLEAR FACTOR 1 HEPATOCYTE NUCLEAR FACTOR 1-BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008663.1|UniProtKB=W5MQ80 W5MQ80 PTHR16515:SF22 PR DOMAIN ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM6-RELATED regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008604.1|UniProtKB=W5MQ01 W5MQ01 PTHR24243:SF109 G-PROTEIN COUPLED RECEPTOR NEUROMEDIN-U RECEPTOR 1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015086.1|UniProtKB=W5ND57 W5ND57 PTHR21490:SF0 ENKURIN-RELATED ENKURIN protein binding#GO:0005515;binding#GO:0005488;calmodulin binding#GO:0005516 supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;secretory vesicle#GO:0099503;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;intracellular vesicle#GO:0097708;cytoplasmic microtubule#GO:0005881;vesicle#GO:0031982;microtubule#GO:0005874;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;supramolecular fiber#GO:0099512;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000009763.1|UniProtKB=W5MU71 W5MU71 PTHR10681:SF182 THIOREDOXIN PEROXIDASE THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stress#GO:0006950;hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592;response to stimulus#GO:0050896;catabolic process#GO:0009056 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000012862.1|UniProtKB=W5N5D0 W5N5D0 PTHR42908:SF3 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR-LIKE GTPASE 1 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;translation#GO:0006412;protein metabolic process#GO:0019538 ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000003277.1|UniProtKB=W5M656 W5M656 PTHR15889:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L37 LARGE RIBOSOMAL SUBUNIT PROTEIN ML37 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000001744.1|UniProtKB=W5M0V4 W5M0V4 PTHR21107:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19 protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011426.1|UniProtKB=W5N086 W5N086 PTHR46121:SF1 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STARD3 N-TERMINAL-LIKE PROTEIN binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934;alcohol binding#GO:0043178;lipid binding#GO:0008289;steroid binding#GO:0005496;cholesterol binding#GO:0015485 lipid transport#GO:0006869;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;sterol transport#GO:0015918;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;late endosome membrane#GO:0031902;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle membrane contact site#GO:0044232 LEPOC|Ensembl=ENSLOCG00000010517.1|UniProtKB=W5MWY1 W5MWY1 PTHR23351:SF52 FOS TRANSCRIPTION FACTOR-RELATED PROTEIN C-FOS sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000013559.1|UniProtKB=W5N7W4 W5N7W4 PTHR19384:SF84 NITRIC OXIDE SYNTHASE-RELATED METHIONINE SYNTHASE REDUCTASE nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;anion binding#GO:0043168;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity, acting on metal ions#GO:0016722;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;sulfur compound metabolic process#GO:0006790;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003047.1|UniProtKB=W5M5G0 W5M5G0 PTHR24061:SF418 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003440.1|UniProtKB=W5M6R1 W5M6R1 PTHR22696:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF26 E3 UBIQUITIN-PROTEIN LIGASE RNF26 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014148.1|UniProtKB=W5N9X3 W5N9X3 PTHR25465:SF26 B-BOX DOMAIN CONTAINING FINTRIM FAMILY, MEMBER 99 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012802.1|UniProtKB=W5N547 W5N547 PTHR14963:SF7 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 19 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000000216.1|UniProtKB=W5LVT3 W5LVT3 PTHR46645:SF1 GRAM DOMAIN-CONTAINING PROTEIN 2B-RELATED GRAM DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013910.1|UniProtKB=W5N950 W5N950 PTHR45620:SF29 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010129.1|UniProtKB=W5MVI6 W5MVI6 PTHR15426:SF6 PROTEIN DEPP1 PROTEIN DEPP1 regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000000156.1|UniProtKB=W5LVM5 W5LVM5 PTHR14187:SF5 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12A LEPOC|Ensembl=ENSLOCG00000015870.1|UniProtKB=W5NFY1 W5NFY1 PTHR12653:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006941.1|UniProtKB=W5MJ44 W5MJ44 PTHR23302:SF42 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 7 passive transmembrane transporter activity#GO:0022803;gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000010938.1|UniProtKB=W5MYF5 W5MYF5 PTHR10218:SF67 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1 GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;response to external stimulus#GO:0009605;system process#GO:0003008;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;visual perception#GO:0007601;response to light stimulus#GO:0009416;signaling#GO:0023052;sensory perception of light stimulus#GO:0050953;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;nervous system process#GO:0050877;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;cilium#GO:0005929;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562 G-protein#PC00020;heterotrimeric G-protein#PC00117 Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid proenkephalin pathway#P05915>G-protein#P05994;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;PI3 kinase pathway#P00048>Galpha#P01199;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gtalpha#P00760;Enkephalin release#P05913>G-Protein (i)#P05974 LEPOC|Ensembl=ENSLOCG00000007455.1|UniProtKB=W5MKY7 W5MKY7 PTHR23295:SF5 NUCLEAR RECEPTOR COACTIVATOR 5-RELATED SI:CH211-216L23.2 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000003978.1|UniProtKB=W5M8S6 W5M8S6 PTHR10670:SF0 DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A hydrolase activity#GO:0016787;DNA-directed DNA polymerase activity#GO:0003887;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;exonuclease activity#GO:0004527;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;transferase activity#GO:0016740;DNA exonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;3'-5' exonuclease activity#GO:0008408 cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;epsilon DNA polymerase complex#GO:0008622;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005645.1|UniProtKB=W5MEL2 W5MEL2 PTHR31078:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013380.1|UniProtKB=W5N785 W5N785 PTHR24211:SF0 LIM DOMAIN-CONTAINING PROTEIN LIM AND CYSTEINE-RICH DOMAINS PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of calcineurin-NFAT signaling cascade#GO:0070884;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of muscle system process#GO:0090257;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of system process#GO:0044057;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of calcium-mediated signaling#GO:0050850;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003347.1|UniProtKB=W5M6E2 W5M6E2 PTHR24409:SF313 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN X-LINKED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000015974.1|UniProtKB=W5NGA7 W5NGA7 PTHR19282:SF154 TETRASPANIN TETRASPANIN-33 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015610.1|UniProtKB=W5NF08 W5NF08 PTHR43139:SF52 SI:DKEY-122A22.2 MESODERM-SPECIFIC TRANSCRIPT PROTEIN protein modifying enzyme#PC00260;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000017328.1|UniProtKB=W5NLC4 W5NLC4 PTHR22639:SF13 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3-LIKE viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000006604.1|UniProtKB=W5MHW9 W5MHW9 PTHR48033:SF9 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN TAR DNA-BINDING PROTEIN 43 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001784.1|UniProtKB=W5M130 W5M130 PTHR11947:SF21 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 3, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015382.1|UniProtKB=W5NE80 W5NE80 PTHR46007:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000001690.1|UniProtKB=W5M0P2 W5M0P2 PTHR22655:SF2 ATP-DEPENDENT RNA HELICASE TDRD12-RELATED ATP-DEPENDENT RNA HELICASE TDRD12-RELATED piRNA processing#GO:0034587;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000004493.1|UniProtKB=W5MAG3 W5MAG3 PTHR21444:SF14 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 LEPOC|Ensembl=ENSLOCG00000005364.1|UniProtKB=W5MDM6 W5MDM6 PTHR16296:SF2 UNCHARACTERIZED HYPOTHALAMUS PROTEIN HT007 TRANSMEMBRANE PROTEIN 126A protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000005593.1|UniProtKB=W5MEE2 W5MEE2 PTHR24232:SF21 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;response to stimulus#GO:0050896;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010910.1|UniProtKB=W5MYC2 W5MYC2 PTHR12596:SF1 EXPORTIN 4,7-RELATED EXPORTIN-4 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein export from nucleus#GO:0006611;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;protein transport#GO:0015031 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;nucleus#GO:0005634 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012343.1|UniProtKB=W5N3I9 W5N3I9 PTHR44472:SF5 DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 4 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000017731.1|UniProtKB=W5NMH6 W5NMH6 PTHR18843:SF7 TORSIN-1A-INTERACTING PROTEIN SI:DKEYP-82A1.6 cellular process#GO:0009987;cellular component organization#GO:0016043;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000002245.1|UniProtKB=W5M2M1 W5M2M1 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN DMBT1 cargo receptor activity#GO:0038024 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016237.1|UniProtKB=W5NHB1 W5NHB1 PTHR23506:SF44 GH10249P MFS-TYPE TRANSPORTER SLC18B1 monoatomic cation transmembrane transporter activity#GO:0008324;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle#GO:0030133 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016361.1|UniProtKB=W5NHU4 W5NHU4 PTHR10257:SF6 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT ALPHA ISOFORM enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle process#GO:0022402;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000015471.1|UniProtKB=W5NEI3 W5NEI3 PTHR23055:SF164 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000016587.1|UniProtKB=W5NIN0 W5NIN0 PTHR15758:SF2 BCL-2-LIKE PROTEIN 13 BCL-2-LIKE PROTEIN 13 LEPOC|Ensembl=ENSLOCG00000016479.1|UniProtKB=W5NIA1 W5NIA1 PTHR19282:SF202 TETRASPANIN PERIPHERIN-2 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014511.1|UniProtKB=W5NB50 W5NB50 PTHR45995:SF1 FAMILY NOT NAMED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 4 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000015684.1|UniProtKB=W5NF99 W5NF99 PTHR10071:SF106 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANS-ACTING T-CELL-SPECIFIC TRANSCRIPTION FACTOR GATA-3 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;embryonic organ development#GO:0048568;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;embryo development#GO:0009790;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of epithelial cell differentiation#GO:0030856;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;immune system development#GO:0002520;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013378.1|UniProtKB=W5N779 W5N779 PTHR16466:SF6 TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;telomere organization#GO:0032200;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance via telomere lengthening#GO:0010833;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;telomere capping#GO:0016233;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nuclear telomere cap complex#GO:0000783;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009523.1|UniProtKB=W5MTD1 W5MTD1 PTHR19139:SF161 AQUAPORIN TRANSPORTER AQUAPORIN-1 carbohydrate transmembrane transporter activity#GO:0015144;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372 response to abiotic stimulus#GO:0009628;hyperosmotic response#GO:0006972;homeostatic process#GO:0042592;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;fluid transport#GO:0042044;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;renal system process#GO:0003014;response to stress#GO:0006950;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transport#GO:0006810;chemical homeostasis#GO:0048878;response to osmotic stress#GO:0006970;multicellular organismal-level homeostasis#GO:0048871;system process#GO:0003008;establishment of localization#GO:0051234;water transport#GO:0006833 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012190.1|UniProtKB=W5N2Y0 W5N2Y0 PTHR10638:SF4 COPPER AMINE OXIDASE AMINE OXIDASE [COPPER-CONTAINING] 2 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;copper ion binding#GO:0005507;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 oxidoreductase#PC00176;oxidase#PC00175 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 LEPOC|Ensembl=ENSLOCG00000004910.1|UniProtKB=W5MC73 W5MC73 PTHR24223:SF357 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 4 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000009977.1|UniProtKB=W5MUY8 W5MUY8 PTHR47410:SF6 TOLL-LIKE RECEPTOR 7-RELATED TOLL LIKE RECEPTOR 7 signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;intracellular signal transduction#GO:0035556;response to virus#GO:0009615;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;canonical NF-kappaB signal transduction#GO:0007249;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;regulation of gene expression#GO:0010468;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of gene expression#GO:0010628;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;defense response to virus#GO:0051607;toll-like receptor signaling pathway#GO:0002224;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008501.1|UniProtKB=W5MPN4 W5MPN4 PTHR45971:SF3 PHOX (PX) DOMAIN-CONTAINING PROTEIN RUN DOMAIN BECLIN-1-INTERACTING AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 regulation of autophagosome maturation#GO:1901096;regulation of endocytosis#GO:0030100;negative regulation of cellular process#GO:0048523;regulation of localization#GO:0032879;negative regulation of autophagy#GO:0010507;regulation of macroautophagy#GO:0016241;regulation of transport#GO:0051049;regulation of catabolic process#GO:0009894;negative regulation of macroautophagy#GO:0016242;regulation of protein-containing complex disassembly#GO:0043244;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of catabolic process#GO:0009895;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of cellular component organization#GO:0051129;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 LEPOC|Ensembl=ENSLOCG00000003835.1|UniProtKB=W5M871 W5M871 PTHR11866:SF4 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN F2-ALPHA RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological quality#GO:0065008;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 LEPOC|Ensembl=ENSLOCG00000014986.1|UniProtKB=W5NCU1 W5NCU1 PTHR24232:SF83 G-PROTEIN COUPLED RECEPTOR GENE 5127-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011505.1|UniProtKB=W5N0H6 W5N0H6 PTHR32337:SF2 NUCLEOLAR PROTEIN 7 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN NOL7 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013302.1|UniProtKB=W5N6Y4 W5N6Y4 PTHR11360:SF19 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 13 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006050.1|UniProtKB=W5MFZ4 W5MFZ4 PTHR24355:SF1 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE-RELATED PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000007890.1|UniProtKB=W5MMH3 W5MMH3 PTHR10954:SF7 RIBONUCLEASE H2 SUBUNIT A RIBONUCLEASE H2 SUBUNIT A nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494 endoribonuclease#PC00094 DNA replication#P00017>RNase H#P00538 LEPOC|Ensembl=ENSLOCG00000011210.1|UniProtKB=W5MZG8 W5MZG8 PTHR11363:SF4 60S RIBOSOMAL PROTEIN L3-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL3 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000015716.1|UniProtKB=W5NFD6 W5NFD6 PTHR24347:SF252 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;calmodulin binding#GO:0005516;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of granulocyte chemotaxis#GO:0071622;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of leukocyte migration#GO:0002685;signaling#GO:0023052;regulation of chemotaxis#GO:0050920;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;regulation of response to external stimulus#GO:0032101;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000008568.1|UniProtKB=W5MPW1 W5MPW1 PTHR15825:SF0 UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-FOLD MODIFIER 1 cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;process utilizing autophagic mechanism#GO:0061919;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;autophagy#GO:0006914;response to stress#GO:0006950;reticulophagy#GO:0061709;macroautophagy#GO:0016236;response to stimulus#GO:0050896;catabolic process#GO:0009056 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007657.1|UniProtKB=W5MLM8 W5MLM8 PTHR19432:SF7 SUGAR TRANSPORTER POLYAMINE-TRANSPORTER SLC45A4 carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000004315.1|UniProtKB=W5M9Y0 W5M9Y0 PTHR45615:SF29 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-7B actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 LEPOC|Ensembl=ENSLOCG00000016406.1|UniProtKB=W5NI01 W5NI01 PTHR24034:SF137 EGF-LIKE DOMAIN-CONTAINING PROTEIN SI:DKEY-163F14.6 cytokine binding#GO:0019955;growth factor binding#GO:0019838;protein binding#GO:0005515;transforming growth factor beta binding#GO:0050431;binding#GO:0005488 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000010497.1|UniProtKB=W5MWV9 W5MWV9 PTHR21084:SF1 DENSE INCISORS SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 38 LEPOC|Ensembl=ENSLOCG00000005939.1|UniProtKB=W5MFL2 W5MFL2 PTHR12176:SF86 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE METHYLTRANSFERASE 4 protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001934.1|UniProtKB=W5M1H9 W5M1H9 PTHR31548:SF4 CLARIN CLARIN-1 multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;system process#GO:0003008;nervous system process#GO:0050877;neuromuscular process#GO:0050905;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600 LEPOC|Ensembl=ENSLOCG00000018331.1|UniProtKB=W5NP73 W5NP73 PTHR14581:SF4 FAMILY NOT NAMED PROLINE-RICH PROTEIN 15 LEPOC|Ensembl=ENSLOCG00000000345.1|UniProtKB=W5LW70 W5LW70 PTHR10978:SF5 SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494 dehydrogenase#PC00092 TCA cycle#P00051>Succinate Dehydrogenase#P01273 LEPOC|Ensembl=ENSLOCG00000005386.1|UniProtKB=W5MDN5 W5MDN5 PTHR23093:SF18 SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 GLUTAMATE RICH 6 LEPOC|Ensembl=ENSLOCG00000016687.1|UniProtKB=W5NJ07 W5NJ07 PTHR45827:SF2 SORTING NEXIN SORTING NEXIN-9 ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091 endocytosis#GO:0006897;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cell division#GO:0051301;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;plasma membrane organization#GO:0007009;cellular localization#GO:0051641;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;membrane invagination#GO:0010324;transport#GO:0006810 cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006028.1|UniProtKB=W5MFW9 W5MFW9 PTHR10271:SF29 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;antiviral innate immune response#GO:0140374;cellular response to cytokine stimulus#GO:0071345;defense response to virus#GO:0051607;response to peptide#GO:1901652;response to virus#GO:0009615;immune system process#GO:0002376;response to other organism#GO:0051707;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008620.1|UniProtKB=W5MQ22 W5MQ22 PTHR24417:SF8 SERINE/THREONINE-PROTEIN KINASE LMTK1 SERINE_THREONINE-PROTEIN KINASE LMTK2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000000234.1|UniProtKB=W5LVV1 W5LVV1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012610.1|UniProtKB=W5N4G1 W5N4G1 PTHR13419:SF2 ZINC FINGER-CONTAINING CXXC-TYPE ZINC FINGER PROTEIN 5 sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;nucleic acid binding#GO:0003676;binding#GO:0005488;small molecule binding#GO:0036094;DNA binding#GO:0003677 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015753.1|UniProtKB=W5NFJ2 W5NFJ2 PTHR48012:SF17 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCKR#P00311 LEPOC|Ensembl=ENSLOCG00000013155.1|UniProtKB=W5N6F1 W5N6F1 PTHR11691:SF76 TYPE I INTERFERON INTEFERON PHI 4-RELATED response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;T cell activation#GO:0042110;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;cell activation involved in immune response#GO:0002263;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;B cell activation involved in immune response#GO:0002312;response to cytokine#GO:0034097;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;defense response to other organism#GO:0098542;T cell activation involved in immune response#GO:0002286;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;lymphocyte activation involved in immune response#GO:0002285;signal transduction#GO:0007165;cellular process#GO:0009987;B cell activation#GO:0042113;humoral immune response#GO:0006959;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252;natural killer cell activation#GO:0030101;leukocyte activation involved in immune response#GO:0002366;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cytokine-mediated signaling pathway#GO:0019221;cell activation#GO:0001775;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;adaptive immune response#GO:0002250;response to other organism#GO:0051707;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 interferon superfamily#PC00127;cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000000657.1|UniProtKB=W5LX75 W5LX75 PTHR11458:SF0 DELTA-AMINOLEVULINIC ACID DEHYDRATASE DELTA-AMINOLEVULINIC ACID DEHYDRATASE hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 porphyrin-containing compound biosynthetic process#GO:0006779;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;tetrapyrrole biosynthetic process#GO:0033014;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydratase#PC00091 Heme biosynthesis#P02746>porphobilinogen synthase#P02979 LEPOC|Ensembl=ENSLOCG00000015425.1|UniProtKB=W5NEC4 W5NEC4 PTHR13367:SF3 UBIQUITIN THIOESTERASE TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 3 transferase activity#GO:0016740;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;aminoacyltransferase activity#GO:0016755;peptidase activity#GO:0008233;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;ubiquitin-protein transferase activity#GO:0004842 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of response to external stimulus#GO:0032102;negative regulation of innate immune response#GO:0045824;negative regulation of signal transduction#GO:0009968;positive regulation of Wnt signaling pathway#GO:0030177;regulation of response to external stimulus#GO:0032101;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;post-translational protein modification#GO:0043687;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of innate immune response#GO:0045088;modification-dependent protein catabolic process#GO:0019941;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;catabolic process#GO:0009056;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;negative regulation of immune response#GO:0050777;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protease#PC00190;cysteine protease#PC00081 Toll receptor signaling pathway#P00054>A20#P01348 LEPOC|Ensembl=ENSLOCG00000005368.1|UniProtKB=W5MDL1 W5MDL1 GFM2 PTHR43261:SF9 TRANSLATION ELONGATION FACTOR G-RELATED RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;mitochondrial gene expression#GO:0140053;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 translation factor#PC00223;translational protein#PC00263;translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000004940.1|UniProtKB=W5MC35 W5MC35 PTHR24103:SF602 E3 UBIQUITIN-PROTEIN LIGASE TRIM RING-TYPE E3 UBIQUITIN TRANSFERASE catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008669.1|UniProtKB=W5MQ82 W5MQ82 PTHR47403:SF2 LOC100145250 PROTEIN N-ACETYLTRANSFERASE 16, LIKE ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000009995.1|UniProtKB=W5MV25 W5MV25 PTHR13123:SF6 LD30288P F-BOX ONLY PROTEIN 32 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 nucleus#GO:0005634;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 LEPOC|Ensembl=ENSLOCG00000007774.1|UniProtKB=W5MM31 W5MM31 PTHR28682:SF1 INHIBITORY SYNAPTIC FACTOR 2A-RELATED INHIBITORY SYNAPTIC FACTOR 2A signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;cell surface receptor signaling pathway#GO:0007166;system process#GO:0003008;regulation of membrane potential#GO:0042391;regulation of biological process#GO:0050789;regulation of postsynaptic membrane potential#GO:0060078;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;chemical synaptic transmission, postsynaptic#GO:0099565;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;nervous system process#GO:0050877;trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;cell communication#GO:0007154 neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;cell junction#GO:0030054;postsynaptic density#GO:0014069 LEPOC|Ensembl=ENSLOCG00000002764.1|UniProtKB=W5M4F0 W5M4F0 PTHR18934:SF118 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX33 isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase I#GO:0045943;positive regulation of RNA biosynthetic process#GO:1902680;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000011828.1|UniProtKB=W5N1N9 W5N1N9 PTHR23086:SF21 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 ALPHA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transferase#PC00220;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000007214.1|UniProtKB=W5MK37 W5MK37 PTHR23192:SF27 OLFACTOMEDIN-RELATED NOELIN-2 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008397.1|UniProtKB=W5MP98 W5MP98 PTHR24072:SF105 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1-RELATED protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;actin filament organization#GO:0007015;neurogenesis#GO:0022008;axon guidance#GO:0007411;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cell morphogenesis involved in neuron differentiation#GO:0048667;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;cortical cytoskeleton organization#GO:0030865;system development#GO:0048731;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of developmental process#GO:0050793;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;generation of neurons#GO:0048699;establishment or maintenance of cell polarity#GO:0007163;Rac protein signal transduction#GO:0016601;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;signaling#GO:0023052;cell differentiation#GO:0030154;cell projection organization#GO:0030030;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;intracellular vesicle#GO:0097708;vesicle#GO:0031982 G-protein#PC00020;small GTPase#PC00208 FGF signaling pathway#P00021>Rac#P00645;Ras Pathway#P04393>Rac#P04559;EGF receptor signaling pathway#P00018>Rac#P00564;T cell activation#P00053>rac#P01324;Huntington disease#P00029>Rac#P00775;Integrin signalling pathway#P00034>Rac#P00927;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;B cell activation#P00010>Rac#P00385;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;p38 MAPK pathway#P05918>Rac#P06021;Axon guidance mediated by semaphorins#P00007>Rac#P00340;Axon guidance mediated by netrin#P00009>Rac#P00366;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523 LEPOC|Ensembl=ENSLOCG00000003410.1|UniProtKB=W5M6P1 W5M6P1 PTHR10915:SF6 SYNDECAN SYNDECAN-2 anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;system development#GO:0048731;regulation of cell junction assembly#GO:1901888;regulation of cellular process#GO:0050794;dendrite morphogenesis#GO:0048813;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;dendrite development#GO:0016358;neuron development#GO:0048666;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;regulation of synapse organization#GO:0050807;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002540.1|UniProtKB=W5M3P6 W5M3P6 PTHR23138:SF94 RAN BINDING PROTEIN RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intracellular transport#GO:0046907;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nuclear transport#GO:0051169;nuclear export#GO:0051168 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016659.1|UniProtKB=W5NIX0 W5NIX0 PTHR12126:SF11 NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL binding#GO:0005488;protein-containing complex binding#GO:0044877 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013631.1|UniProtKB=W5N845 W5N845 PTHR12804:SF0 MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23 SIGNAL PEPTIDASE COMPLEX SUBUNIT 3 establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;establishment of protein localization to endoplasmic reticulum#GO:0072599;biosynthetic process#GO:0009058;metabolic process#GO:0008152;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;protein targeting to ER#GO:0045047;primary metabolic process#GO:0044238;protein targeting#GO:0006605;localization#GO:0051179;protein metabolic process#GO:0019538 membrane#GO:0016020;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 LEPOC|Ensembl=ENSLOCG00000009575.1|UniProtKB=W5MTN8 W5MTN8 PTHR24035:SF138 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 6 membrane organization#GO:0061024;endocytosis#GO:0006897;cellular process#GO:0009987;cellular component organization#GO:0016043;establishment of localization#GO:0051234;import into cell#GO:0098657;apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;transport#GO:0006810;membrane invagination#GO:0010324;phagocytosis#GO:0006909 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000004098.1|UniProtKB=W5M938 W5M938 PTHR19375:SF379 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein refolding#GO:0042026;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 LEPOC|Ensembl=ENSLOCG00000018007.1|UniProtKB=W5NN99 W5NN99 PTHR24133:SF14 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 9 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018171.1|UniProtKB=W5NNR3 W5NNR3 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013076.1|UniProtKB=W5N658 W5N658 PTHR12542:SF41 EXOCYST COMPLEX PROTEIN EXO70 EXOCYST COMPLEX COMPONENT 7 export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;secretion by cell#GO:0032940;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;transport#GO:0006810 cell cortex#GO:0005938;cell periphery#GO:0071944;exocyst#GO:0000145;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015160.1|UniProtKB=W5NDE9 W5NDE9 PTHR16078:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 87 COILED-COIL DOMAIN-CONTAINING PROTEIN 87 LEPOC|Ensembl=ENSLOCG00000002848.1|UniProtKB=W5M4P7 W5M4P7 PTHR23074:SF83 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 vacuole organization#GO:0007033;protein metabolic process#GO:0019538;cellular localization#GO:0051641;localization#GO:0051179;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;ubiquitin-dependent protein catabolic process#GO:0006511;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;transport#GO:0006810;macromolecule catabolic process#GO:0009057;intracellular transport#GO:0046907;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000005908.1|UniProtKB=W5MFH4 W5MFH4 PTHR46550:SF7 F-BOX ONLY PROTEIN 3 F-BOX ONLY PROTEIN 3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000188.1|UniProtKB=W5LVQ2 W5LVQ2 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005720.1|UniProtKB=W5MEU3 W5MEU3 PTHR16231:SF2 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 7 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;response to tumor necrosis factor#GO:0034612;signal transduction#GO:0007165;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000008692.1|UniProtKB=W5MQB5 W5MQB5 PTHR32012:SF0 TRANSMEMBRANE PROTEIN 182-RELATED TRANSMEMBRANE PROTEIN 182 LEPOC|Ensembl=ENSLOCG00000015405.1|UniProtKB=W5NEA1 W5NEA1 PTHR45953:SF1 IDURONATE 2-SULFATASE IDURONATE 2-SULFATASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017289.1|UniProtKB=W5NL78 W5NL78 PTHR24249:SF426 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR SI:DKEY-7C18.19 PROTEIN-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011763.1|UniProtKB=W5N1G7 W5N1G7 PTHR13793:SF93 PHD FINGER PROTEINS PROTEIN AF-10 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000017467.1|UniProtKB=W5NLR3 W5NLR3 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011023.1|UniProtKB=W5MYS1 W5MYS1 PTHR11267:SF98 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX15 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 LEPOC|Ensembl=ENSLOCG00000008531.1|UniProtKB=W5MPS4 W5MPS4 PTHR18945:SF764 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3E monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 response to chemical#GO:0042221;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;response to nitrogen compound#GO:1901698;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000001079.1|UniProtKB=W5LYK8 W5LYK8 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000012298.1|UniProtKB=W5N3C5 W5N3C5 PTHR13563:SF20 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG A RNA binding#GO:0003723;tRNA binding#GO:0000049;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000002916.1|UniProtKB=W5M4X8 W5M4X8 PTHR44793:SF1 MATRIX REMODELING-ASSOCIATED PROTEIN 8 MATRIX REMODELING-ASSOCIATED PROTEIN 8 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular process#GO:0009987 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000808.1|UniProtKB=W5LXP3 W5LXP3 PTHR31394:SF1 TRANSMEMBRANE PROTEIN 199 VACUOLAR ATPASE ASSEMBLY PROTEIN VMA12 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000000325.1|UniProtKB=W5LW46 W5LW46 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000018231.1|UniProtKB=W5NNX3 W5NNX3 PTHR15258:SF3 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 3 protein binding#GO:0005515;growth factor binding#GO:0019838;binding#GO:0005488 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000005208.1|UniProtKB=W5MD17 W5MD17 PTHR11599:SF42 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-7 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000000602.1|UniProtKB=W5LX10 W5LX10 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003306.1|UniProtKB=W5M6B1 W5M6B1 PTHR11430:SF121 LIPOCALIN COMPLEMENT COMPONENT 8, GAMMA POLYPEPTIDE transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000004997.1|UniProtKB=W5MCC9 W5MCC9 PTHR24271:SF97 KALLIKREIN-RELATED MAST CELL PROTEASE 2 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000006084.1|UniProtKB=W5MG43 W5MG43 PTHR10285:SF131 URIDINE KINASE URIDINE-CYTIDINE KINASE 2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;nucleoside kinase activity#GO:0019206;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149 LEPOC|Ensembl=ENSLOCG00000008796.1|UniProtKB=W5MQP5 W5MQP5 PTHR15917:SF0 FAMILY NOT NAMED PROTEIN LARGEN positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of anatomical structure size#GO:0090066;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of translation#GO:0045727;regulation of biological quality#GO:0065008;regulation of cell size#GO:0008361;positive regulation of protein metabolic process#GO:0051247 LEPOC|Ensembl=ENSLOCG00000011692.1|UniProtKB=W5N158 W5N158 PTHR11616:SF102 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER SLC6A17 alanine transport#GO:0032328;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865;branched-chain amino acid transport#GO:0015803;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;sodium ion transport#GO:0006814;L-leucine transport#GO:0015820;metal ion transport#GO:0030001 plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 LEPOC|Ensembl=ENSLOCG00000014513.1|UniProtKB=W5NB59 W5NB59 PTHR12756:SF5 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 4 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;hydrolase activity#GO:0016787;protein binding#GO:0005515;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;binding#GO:0005488;metallopeptidase activity#GO:0008237 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000004978.1|UniProtKB=W5MCB0 W5MCB0 PTHR16515:SF64 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 1 ISOFORM X1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000007879.1|UniProtKB=W5MMF9 W5MMF9 PTHR10517:SF25 FOLATE RECEPTOR RETBINDIN ISOFORM X1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;signaling receptor activity#GO:0038023;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;molecular transducer activity#GO:0060089 transport#GO:0006810;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234;vitamin transport#GO:0051180 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008234.1|UniProtKB=W5MNN7 W5MNN7 PTHR11738:SF186 MHC CLASS I NK CELL RECEPTOR CLUSTER HOMOLOG OF IMMUNOGLOBULIN LIKE RECEPTOR 1AB 3-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015122.1|UniProtKB=W5NDA4 W5NDA4 PTHR14383:SF2 SWAP-70 RECOMBINASE DIFFERENTIALLY EXPRESSED IN FDCP 6 HOMOLOG guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cytoskeleton organization#GO:0007010;intracellular signaling cassette#GO:0141124;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;actin filament-based process#GO:0030029;actin filament polymerization#GO:0030041;response to stimulus#GO:0050896;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular component organization#GO:0016043;protein polymerization#GO:0051258;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013104.1|UniProtKB=W5N682 W5N682 PTHR35539:SF1 CDNA SEQUENCE BC048562 CILIARY MICROTUBULE INNER PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000002213.1|UniProtKB=W5M2I1 W5M2I1 PTHR22850:SF90 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP4 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000012986.1|UniProtKB=W5N5T7 W5N5T7 PTHR10488:SF1 GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011851.1|UniProtKB=W5N1S4 W5N1S4 PTHR12883:SF0 ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED PAT COMPLEX SUBUNIT CCDC47 localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein insertion into membrane#GO:0051205 organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;protein folding chaperone complex#GO:0101031;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000000299.1|UniProtKB=W5LW19 W5LW19 PTHR43178:SF18 LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED CHAIN ALPHA_KETOACID DEHYDROGENASE COMPLEX LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;oxidoreductase complex#GO:1990204;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234 acetyltransferase#PC00038;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011104.1|UniProtKB=W5MZ38 W5MZ38 PTHR24390:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 366 ISOFORM X1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000010871.1|UniProtKB=W5MY69 W5MY69 PTHR16276:SF1 PENTATRICOPEPTIDE REPEAT DOMAIN-CONTAINING PROTEIN 3 SMALL RIBOSOMAL SUBUNIT PROTEIN MS39 ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000005441.1|UniProtKB=W5MDU9 W5MDU9 PTHR19278:SF9 OROTATE PHOSPHORIBOSYLTRANSFERASE URIDINE 5'-MONOPHOSPHATE SYNTHASE glycosyltransferase activity#GO:0016757;lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbon-carbon lyase activity#GO:0016830;pentosyltransferase activity#GO:0016763 ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;pyrimidine nucleobase metabolic process#GO:0006206;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165 transferase#PC00220;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Orotate phosphoribosyltransferase#P02922 LEPOC|Ensembl=ENSLOCG00000013630.1|UniProtKB=W5N851 W5N851 PTHR22765:SF470 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF167 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;biological regulation#GO:0065007;cellular process#GO:0009987;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell cycle#GO:0051726;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015307.1|UniProtKB=W5NDX6 W5NDX6 PTHR46090:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B ARF LIKE GTPASE 13A localization#GO:0051179;non-motile cilium assembly#GO:1905515;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;localization within membrane#GO:0051668;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987 cilium#GO:0005929;non-motile cilium#GO:0097730;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;cell periphery#GO:0071944;membrane#GO:0016020;ciliary membrane#GO:0060170;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000017900.1|UniProtKB=W5NMZ4 W5NMZ4 PTHR19282:SF51 TETRASPANIN TETRASPANIN-32 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001199.1|UniProtKB=W5LYZ4 W5LYZ4 PTHR11588:SF515 TUBULIN TUBULIN BETA CHAIN ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 LEPOC|Ensembl=ENSLOCG00000003472.1|UniProtKB=W5M6X1 W5M6X1 PTHR13083:SF3 WD REPEAT-CONTAINING PROTEIN 91 WD REPEAT-CONTAINING PROTEIN 91 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;early endosome membrane#GO:0031901;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000010958.1|UniProtKB=W5MYI8 W5MYI8 PTHR43323:SF2 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE HYDROXYMETHYLGLUTARYL-COA SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 acetyl-CoA metabolic process#GO:0006084;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA synthase#P00498 LEPOC|Ensembl=ENSLOCG00000016862.1|UniProtKB=W5NJN8 W5NJN8 PTHR10663:SF318 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 3 regulation of biological quality#GO:0065008;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000003692.1|UniProtKB=W5M7N1 W5M7N1 PTHR21093:SF3 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1B LEPOC|Ensembl=ENSLOCG00000010371.1|UniProtKB=W5MWG0 W5MWG0 PTHR43520:SF30 ATP7, ISOFORM B COPPER-TRANSPORTING ATPASE 2 ion binding#GO:0043167;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;cation binding#GO:0043169;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transition metal ion transmembrane transporter activity#GO:0046915;binding#GO:0005488;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;metal ion binding#GO:0046872;monoatomic cation transmembrane transporter activity#GO:0008324;copper ion binding#GO:0005507;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;metal ion transmembrane transporter activity#GO:0046873 chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;copper ion transmembrane transport#GO:0035434 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000011175.1|UniProtKB=W5MZC1 W5MZC1 PTHR24253:SF62 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 6 catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004713.1|UniProtKB=W5MB87 W5MB87 PTHR11937:SF575 ACTIN ACTIN, CYTOPLASMIC 2 structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114 LEPOC|Ensembl=ENSLOCG00000018039.1|UniProtKB=W5NND1 W5NND1 PTHR10656:SF38 CELL FATE DETERMINING PROTEIN MAB21-RELATED NUCLEOTIDYLTRANSFERASE MAB21L1-RELATED nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 nucleotidyltransferase#PC00174;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004437.1|UniProtKB=W5MA94 W5MA94 PTHR14559:SF3 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 9 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;regulation of intracellular signal transduction#GO:1902531 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011286.1|UniProtKB=W5MZR0 W5MZR0 PTHR12478:SF17 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 DNA DAMAGE-INDUCIBLE TRANSCRIPT 4-LIKE PROTEIN regulation of biological process#GO:0050789;regulation of TOR signaling#GO:0032006;apoptotic process#GO:0006915;cellular process#GO:0009987;cell death#GO:0008219;programmed cell death#GO:0012501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 LEPOC|Ensembl=ENSLOCG00000002378.1|UniProtKB=W5M344 W5M344 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004091.1|UniProtKB=W5M923 W5M923 PTHR24543:SF333 MULTICOPPER OXIDASE-RELATED EGF-LIKE REPEAT AND DISCOIDIN I-LIKE DOMAIN-CONTAINING PROTEIN 3 regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014316.1|UniProtKB=W5NAG9 W5NAG9 PTHR13622:SF16 THIAMIN PYROPHOSPHOKINASE SI:DKEY-6N6.2 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110 transferase#PC00220;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000010927.1|UniProtKB=W5MYE1 W5MYE1 PTHR11690:SF298 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT BETA-LIKE monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000005511.1|UniProtKB=W5ME43 W5ME43 PTHR12155:SF50 SCHLAFEN MGC83227 PROTEIN endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000000252.1|UniProtKB=W5LVW9 W5LVW9 PTHR24388:SF109 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 221-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000014906.1|UniProtKB=W5NCJ8 W5NCJ8 PTHR33887:SF4 PB1 DOMAIN-CONTAINING PROTEIN CHROMOSOME X OPEN READING FRAME 65 LEPOC|Ensembl=ENSLOCG00000000398.1|UniProtKB=W5LWC6 W5LWC6 PTHR48071:SF18 SRCR DOMAIN-CONTAINING PROTEIN SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN DMBT1 ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000013602.1|UniProtKB=W5N811 W5N811 PTHR28632:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000013220.1|UniProtKB=W5N6M6 W5N6M6 PTHR46887:SF1 TANDEM C2 DOMAINS NUCLEAR PROTEIN TANDEM C2 DOMAINS NUCLEAR PROTEIN LEPOC|Ensembl=ENSLOCG00000013947.1|UniProtKB=W5N986 W5N986 PTHR47130:SF6 SI:DKEY-19B23.11-RELATED ZONA PELLUCIDA PROTEIN AX 4 LEPOC|Ensembl=ENSLOCG00000007934.1|UniProtKB=W5MMP0 W5MMP0 PTHR45818:SF1 PROTEIN VAV GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV3 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cell migration#GO:0016477;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169;B cell activation#P00010>vav#P00368 LEPOC|Ensembl=ENSLOCG00000003263.1|UniProtKB=W5M644 W5M644 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000010185.1|UniProtKB=W5MVQ9 W5MVQ9 PTHR11860:SF87 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CD300 MOLECULE LIKE FAMILY MEMBER G-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009058.1|UniProtKB=W5MRM7 W5MRM7 PTHR34920:SF1 B-CELL LYMPHOMA/LEUKEMIA 10 B-CELL LYMPHOMA_LEUKEMIA 10 protein kinase binding#GO:0019901;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;molecular function activator activity#GO:0140677;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;transcription coactivator activity#GO:0003713;kinase activator activity#GO:0019209;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;molecular function regulator activity#GO:0098772 positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;immune system process#GO:0002376;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000000011.1|UniProtKB=W5LV55 W5LV55 PTHR14206:SF6 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BAR_IMD DOMAIN-CONTAINING ADAPTER PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;regulation of supramolecular fiber organization#GO:1902903;actin filament bundle assembly#GO:0051017;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004896.1|UniProtKB=W5MBY0 W5MBY0 PTHR24020:SF13 COLLAGEN ALPHA COLLAGEN ALPHA-3(VI) CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863 LEPOC|Ensembl=ENSLOCG00000005291.1|UniProtKB=W5MDC4 W5MDC4 PTHR13497:SF3 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle lumen#GO:0070013;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000013089.1|UniProtKB=W5N668 W5N668 PTHR45711:SF8 CHLORIDE CHANNEL PROTEIN H(+)_CL(-) EXCHANGE TRANSPORTER 3 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;homeostatic process#GO:0042592;monoatomic anion transport#GO:0006820;cellular component organization#GO:0016043;vesicle organization#GO:0016050;cellular homeostasis#GO:0019725;synaptic vesicle maturation#GO:0016188;cellular component organization or biogenesis#GO:0071840;proton transmembrane transport#GO:1902600;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;chloride transport#GO:0006821;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;developmental maturation#GO:0021700;vesicle-mediated transport#GO:0016192;monoatomic anion transmembrane transport#GO:0098656;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;synaptic vesicle#GO:0008021;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;intracellular organelle#GO:0043229;endosome#GO:0005768;exocytic vesicle#GO:0070382;endosome membrane#GO:0010008;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;cell junction#GO:0030054;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;vacuole#GO:0005773;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;lysosomal membrane#GO:0005765 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010484.1|UniProtKB=W5MWU1 W5MWU1 PTHR11471:SF33 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 6 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;apoptotic signaling pathway#GO:0097190;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;programmed cell death#GO:0012501;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;regulation of programmed cell death#GO:0043067;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Apoptosis signaling pathway#P00006>FAS ligand#P00326;FAS signaling pathway#P00020>FasL#P00617 LEPOC|Ensembl=ENSLOCG00000011687.1|UniProtKB=W5N157 W5N157 PTHR14381:SF1 DACTYLIN F-BOX_WD REPEAT-CONTAINING PROTEIN 4 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA damage response#GO:0006974 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461 LEPOC|Ensembl=ENSLOCG00000013909.1|UniProtKB=W5N957 W5N957 PTHR10627:SF67 SCP160 VIGILIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011417.1|UniProtKB=W5N081 W5N081 PTHR11455:SF10 CRYPTOCHROME CRYPTOCHROME CIRCADIAN REGULATOR 3A-RELATED lyase activity#GO:0016829;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;carbon-carbon lyase activity#GO:0016830;DNA binding#GO:0003677;deoxyribodipyrimidine photo-lyase activity#GO:0003904;anion binding#GO:0043168;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 negative regulation of cellular process#GO:0048523;photoperiodism#GO:0009648;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;response to radiation#GO:0009314;negative regulation of macromolecule metabolic process#GO:0010605;regulation of circadian rhythm#GO:0042752;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to light stimulus#GO:0009416;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;rhythmic process#GO:0048511;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;response to abiotic stimulus#GO:0009628;circadian regulation of gene expression#GO:0032922;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA photolyase#PC00014 Circadian clock system#P00015>cry#G01497;Circadian clock system#P00015>Cry#P00505;Circadian clock system#P00015>cry#G01501 LEPOC|Ensembl=ENSLOCG00000014912.1|UniProtKB=W5NCK6 W5NCK6 PTHR43389:SF5 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B, BRAIN ISOFORM intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;proton transmembrane transport#GO:1902600;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting two-sector ATPase complex#GO:0016469;apical part of cell#GO:0045177;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ATP synthase#PC00002;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000009832.1|UniProtKB=W5MUG4 W5MUG4 PTHR14052:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 DNA replication origin binding#GO:0003688;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690 DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nuclear origin of replication recognition complex#GO:0005664;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808 replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000016266.1|UniProtKB=W5NHF4 W5NHF4 PTHR45570:SF1 CARBOXYLIC ESTER HYDROLASE CARBOXYLIC ESTER HYDROLASE hydrolase#PC00121;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015221.1|UniProtKB=W5NDM2 W5NDM2 PTHR24332:SF15 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;tube development#GO:0035295;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;embryonic pattern specification#GO:0009880;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;anterior/posterior axis specification#GO:0009948;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007127.1|UniProtKB=W5MJR7 W5MJR7 PTHR11211:SF14 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cell development#GO:0048468;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000016524.1|UniProtKB=W5NIF3 W5NIF3 PTHR23354:SF68 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED NUCLEAR RECEPTOR COACTIVATOR 7 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;response to oxidative stress#GO:0006979;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000009920.1|UniProtKB=W5MUR7 W5MUR7 PTHR12133:SF2 TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRMT61A tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396 catalytic complex#GO:1902494;transferase complex#GO:1990234;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000006799.1|UniProtKB=W5MIK7 W5MIK7 PTHR12622:SF41 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX3L catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003356.1|UniProtKB=W5M6F2 W5M6F2 PTHR11721:SF3 60S RIBOSOMAL PROTEIN L27A LARGE RIBOSOMAL SUBUNIT PROTEIN UL15 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017371.1|UniProtKB=W5NLG7 W5NLG7 PTHR11214:SF21 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE LACTOSYLCERAMIDE 1,3-N-ACETYL-BETA-D-GLUCOSAMINYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000000828.1|UniProtKB=W5LXR4 W5LXR4 PTHR13814:SF12 FETUIN KININOGEN-1 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678 regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;negative regulation of blood coagulation#GO:0030195;regulation of response to stimulus#GO:0048583;negative regulation of response to wounding#GO:1903035;regulation of response to wounding#GO:1903034;negative regulation of wound healing#GO:0061045;regulation of hemostasis#GO:1900046;negative regulation of cell adhesion#GO:0007162;regulation of coagulation#GO:0050818;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of cell adhesion#GO:0030155;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;negative regulation of hemostasis#GO:1900047;negative regulation of coagulation#GO:0050819;regulation of biological quality#GO:0065008;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of blood coagulation#GO:0030193;regulation of body fluid levels#GO:0050878;regulation of cellular process#GO:0050794;regulation of wound healing#GO:0061041 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>Bradykinin#P00438;Blood coagulation#P00011>HMWK#P00413;Blood coagulation#P00011>Kininogen#P00451 LEPOC|Ensembl=ENSLOCG00000017402.1|UniProtKB=W5NLJ8 W5NLJ8 PTHR10270:SF107 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-14 transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014896.1|UniProtKB=W5NCI3 W5NCI3 PTHR14186:SF25 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED KAZAL-TYPE SERINE PEPTIDASE INHIBITOR DOMAIN 3 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003271.1|UniProtKB=W5M655 W5M655 PTHR18870:SF8 PROTEIN TAG-278-RELATED PROTEIN FAM184B LEPOC|Ensembl=ENSLOCG00000005194.1|UniProtKB=W5MCZ8 W5MCZ8 PTHR24082:SF38 NUCLEAR HORMONE RECEPTOR VITAMIN D3 RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;steroid binding#GO:0005496;transcription regulatory region nucleic acid binding#GO:0001067;lipid binding#GO:0008289;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C4 zinc finger nuclear receptor#PC00169 Vitamin D metabolism and pathway#P04396>VDR#P04606 LEPOC|Ensembl=ENSLOCG00000013710.1|UniProtKB=W5N8E5 W5N8E5 PTHR10696:SF51 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 cellular process#GO:0009987;carnitine metabolic process#GO:0009437;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008814.1|UniProtKB=W5MQT7 W5MQT7 CLCN2 PTHR45720:SF6 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN 2 voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic anion channel activity#GO:0008308;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;monoatomic anion transport#GO:0006820 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018288.1|UniProtKB=W5NMA8 W5NMA8 PTHR14758:SF3 AGAP005440-PA PROTEIN FAM110D LEPOC|Ensembl=ENSLOCG00000014898.1|UniProtKB=W5NCJ0 W5NCJ0 PTHR22993:SF27 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 1 DNA N-glycosylase activity#GO:0019104;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;endonuclease activity#GO:0004519 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;base-excision repair#GO:0006284;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000008518.1|UniProtKB=W5MPQ8 W5MPQ8 PTHR15228:SF16 SPERMATHECAL PHYSIOLOGY VARIANT GEM-INTERACTING PROTEIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of small GTPase mediated signal transduction#GO:0051056;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;intracellular signal transduction#GO:0035556;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012639.1|UniProtKB=W5N4K0 W5N4K0 PTHR24050:SF19 PA14 DOMAIN-CONTAINING PROTEIN NEPHRONECTIN LEPOC|Ensembl=ENSLOCG00000015474.1|UniProtKB=W5NEI7 W5NEI7 PTHR11841:SF1 REELIN REELIN lipoprotein particle receptor binding#GO:0070325;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell motility#GO:0048870;developmental process#GO:0032502;neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell migration#GO:0016477;nervous system development#GO:0007399 extracellular region#GO:0005576;neuron projection#GO:0043005;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000012355.1|UniProtKB=W5N3J6 W5N3J6 PTHR13681:SF26 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000001619.1|UniProtKB=W5M0G6 W5M0G6 PTHR10728:SF13 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 lipase activity#GO:0016298;small molecule binding#GO:0036094;ion binding#GO:0043167;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623 metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;lipid metabolic process#GO:0006629;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid catabolic process#GO:0009395;glycerophospholipid metabolic process#GO:0006650;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 phospholipase#PC00186 Oxidative stress response#P00046>cPLA2#P01134;Endothelin signaling pathway#P00019>cPLA2#P00583;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLA2#P00855;VEGF signaling pathway#P00056>cPLA2#P01409;Angiogenesis#P00005>PLA2#P00227;Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;CCKR signaling map#P06959>PLA2#P07086;Angiogenesis#P00005>cPLA2#P00251 LEPOC|Ensembl=ENSLOCG00000005760.1|UniProtKB=W5MF01 W5MF01 PTHR10145:SF6 TRANSCRIPTION ELONGATION FACTOR SPT6 TRANSCRIPTION ELONGATION FACTOR SPT6 binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;nucleosome organization#GO:0034728;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338 transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011542.1|UniProtKB=W5N0M7 W5N0M7 PTHR23113:SF26 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 5 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000002479.1|UniProtKB=W5M3E7 W5M3E7 PTHR11256:SF32 BCL-2 RELATED BCL2 LIKE 16 ISOFORM X1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;response to stress#GO:0006950;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967 LEPOC|Ensembl=ENSLOCG00000000110.1|UniProtKB=W5LVG5 W5LVG5 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012181.1|UniProtKB=W5N2X4 W5N2X4 PTHR10660:SF4 PROTEASOME REGULATOR PA28 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 3 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134;enzyme activator activity#GO:0008047;endopeptidase regulator activity#GO:0061135 regulation of catabolic process#GO:0009894;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of mitotic cell cycle#GO:0007346;regulation of proteasomal protein catabolic process#GO:0061136;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of protein catabolic process#GO:0042176;regulation of cell cycle phase transition#GO:1901987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000018243.1|UniProtKB=W5NNY5 W5NNY5 PTHR12887:SF18 NANOS PROTEIN NANOS HOMOLOG 1 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;oogenesis#GO:0048477;negative regulation of translation#GO:0017148;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;negative regulation of protein metabolic process#GO:0051248 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017111.1|UniProtKB=W5NKI8 W5NKI8 PTHR11255:SF92 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE IOTA kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;neutral lipid metabolic process#GO:0006638;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165 plasma membrane#GO:0005886;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000012813.1|UniProtKB=W5N559 W5N559 PTHR46171:SF1 GH10160P E3 UBIQUITIN-PROTEIN LIGASE RNF38 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 LEPOC|Ensembl=ENSLOCG00000010248.1|UniProtKB=W5MW01 W5MW01 PTHR10316:SF12 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell communication#GO:0007154;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of protein localization to membrane#GO:1905475 cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cell-cell junction#GO:0005911 LEPOC|Ensembl=ENSLOCG00000012133.1|UniProtKB=W5N2S0 W5N2S0 PTHR23063:SF10 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 3 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004722.1|UniProtKB=W5MBA5 W5MBA5 PTHR23180:SF241 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043 vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007454.1|UniProtKB=W5MKY3 W5MKY3 PTHR24343:SF301 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 5 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017782.1|UniProtKB=W5NMM7 W5NMM7 PTHR45773:SF5 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 5 multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of synapse assembly#GO:0051965;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;system development#GO:0048731;regulation of cell junction assembly#GO:1901888;positive regulation of cellular component biogenesis#GO:0044089;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;regulation of synapse organization#GO:0050807;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007033.1|UniProtKB=W5MJF3 W5MJF3 PTHR46179:SF29 ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZFP91 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000003753.1|UniProtKB=W5M7W5 W5M7W5 PTHR24067:SF280 UBIQUITIN-CONJUGATING ENZYME E2 SUMO-CONJUGATING ENZYME UBC9 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;ubiquitin-like protein conjugating enzyme activity#GO:0061650 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein sumoylation#GO:0016925;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;post-translational protein modification#GO:0043687 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014690.1|UniProtKB=W5NBS3 W5NBS3 PTHR14905:SF23 NG37 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 7 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000006980.1|UniProtKB=W5MJ87 W5MJ87 PTHR14024:SF48 PERILIPIN PERILIPIN 6 regulation of localization#GO:0032879;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;lipid storage#GO:0019915;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014957.1|UniProtKB=W5NCQ7 W5NCQ7 PTHR11879:SF36 ASPARTATE AMINOTRANSFERASE ASPARTATE TRANSAMINASE proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000012627.1|UniProtKB=W5N4J4 W5N4J4 PTHR23036:SF197 CYTOKINE RECEPTOR LIF RECEPTOR SUBUNIT ALPHA A-RELATED protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;cytokine receptor activity#GO:0004896 cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011289.1|UniProtKB=W5MZR5 W5MZR5 PTHR14903:SF5 SCLEROSTIN-RELATED SCLEROSTIN DOMAIN-CONTAINING PROTEIN 1 cytokine binding#GO:0019955;protein binding#GO:0005515;binding#GO:0005488 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of BMP signaling pathway#GO:0030514;regulation of BMP signaling pathway#GO:0030510;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008063.1|UniProtKB=W5MN27 W5MN27 PTHR19282:SF216 TETRASPANIN TETRASPANIN-1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009991.1|UniProtKB=W5MV09 W5MV09 PTHR18821:SF8 PROKINETICIN PROKINETICIN-2 endothelial cell proliferation#GO:0001935;epithelial cell proliferation#GO:0050673;cell population proliferation#GO:0008283;cellular process#GO:0009987 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000017081.1|UniProtKB=W5NKF0 W5NKF0 PTHR15955:SF3 RWD DOMAIN CONTAINING PROTEIN 2 RWD DOMAIN-CONTAINING PROTEIN 2A ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000006607.1|UniProtKB=W5MHX4 W5MHX4 PTHR24356:SF246 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 LEPOC|Ensembl=ENSLOCG00000001436.1|UniProtKB=W5LZV5 W5LZV5 PTHR16071:SF2 CHROMOSOME 1 OPEN READING FRAME 112 FIGNL1-INTERACTING REGULATOR OF RECOMBINATION AND MITOSIS LEPOC|Ensembl=ENSLOCG00000001765.1|UniProtKB=W5M111 W5M111 PTHR46160:SF12 ALPHA-TECTORIN-RELATED ALPHA-TECTORIN ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000011706.1|UniProtKB=W5N181 W5N181 PTHR11276:SF28 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE LAMBDA DNA-directed DNA polymerase activity#GO:0003887;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001733.1|UniProtKB=W5M0V1 W5M0V1 PTHR15107:SF4 RETINOBLASTOMA BINDING PROTEIN 8 DNA ENDONUCLEASE RBBP8 DNA binding#GO:0003677;damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via single-strand annealing#GO:0045002;response to stimulus#GO:0050896;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000013410.1|UniProtKB=W5N7C6 W5N7C6 PTHR23268:SF128 T-CELL RECEPTOR BETA CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010118.1|UniProtKB=W5MVG9 W5MVG9 PTHR45775:SF4 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN GEM nucleoside phosphate binding#GO:1901265;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;calcium channel regulator activity#GO:0005246;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000007061.1|UniProtKB=W5MJK6 W5MJK6 PTHR11139:SF71 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE SMG1 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;cellular response to stress#GO:0033554;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018356.1|UniProtKB=W5NP98 W5NP98 PTHR24244:SF0 NEUROPEPTIDE S RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001001.1|UniProtKB=W5LYB8 W5LYB8 PTHR46850:SF1 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 ATP-DEPENDENT CHROMATIN REMODELER CHD9 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005020.1|UniProtKB=W5MCD5 W5MCD5 PTHR12357:SF65 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 1 protein-RNA adaptor activity#GO:0140517;nucleic acid binding#GO:0003676;binding#GO:0005488;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;RNA binding#GO:0003723 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;organelle assembly#GO:0070925;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;cytoplasmic stress granule assembly#GO:0034063;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;RNA destabilization#GO:0050779;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013546.1|UniProtKB=W5N7U6 W5N7U6 PTHR18945:SF59 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT EPSILON transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536;response to chemical#GO:0042221;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;muscle system process#GO:0003012;regulation of biological process#GO:0050789;skeletal muscle contraction#GO:0003009;signaling#GO:0023052;response to stimulus#GO:0050896;nervous system process#GO:0050877;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;acetylcholine receptor signaling pathway#GO:0095500;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;transport#GO:0006810;muscle contraction#GO:0006936;system process#GO:0003008;establishment of localization#GO:0051234;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;membrane depolarization#GO:0051899;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;neuromuscular process#GO:0050905;trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179 cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000017491.1|UniProtKB=W5NLT7 W5NLT7 PTHR11636:SF83 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004937.1|UniProtKB=W5MC33 W5MC33 PTHR15960:SF2 LD44032P UBIQUITIN-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;catabolic process#GO:0009056 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;ESCRT I complex#GO:0000813;membrane#GO:0016020;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000002692.1|UniProtKB=W5M4I9 W5M4I9 PTHR19134:SF206 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;biological regulation#GO:0065007;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;cell communication#GO:0007154;anatomical structure development#GO:0048856 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000013433.1|UniProtKB=W5N7F1 W5N7F1 PTHR24201:SF8 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR B kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell population proliferation#GO:0042127;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell population proliferation#GO:0008285 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 p53 pathway#P00059>ARF#G01574 LEPOC|Ensembl=ENSLOCG00000010627.1|UniProtKB=W5MXA4 W5MXA4 PTHR12119:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C CYTOCHROME B-C1 COMPLEX SUBUNIT 8 electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex III#GO:0045275;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006411.1|UniProtKB=W5MH86 W5MH86 PTHR24248:SF148 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR HISTAMINE H3 RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000334.1|UniProtKB=W5LW54 W5LW54 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000858.1|UniProtKB=W5LXV5 W5LXV5 PTHR10742:SF342 FLAVIN MONOAMINE OXIDASE L-AMINO-ACID OXIDASE ISOFORM X1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520 oxidase#PC00175 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 LEPOC|Ensembl=ENSLOCG00000013395.1|UniProtKB=W5N7A4 W5N7A4 PTHR31239:SF2 NICOLIN 1 NICOLIN-1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000013594.1|UniProtKB=W5N807 W5N807 PTHR15633:SF2 NUCLEOLAR PROTEIN 11 NUCLEOLAR PROTEIN 11 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000013863.1|UniProtKB=W5N8Z6 W5N8Z6 PTHR19376:SF37 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription termination#GO:0006353;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;transcription by RNA polymerase II#GO:0006366;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015878.1|UniProtKB=W5NFZ6 W5NFZ6 PTHR15722:SF2 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 172 HOMOLOG cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014936.1|UniProtKB=W5NCM9 W5NCM9 PTHR23235:SF78 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000017620.1|UniProtKB=W5NM66 W5NM66 PTHR18884:SF128 SEPTIN SI:CH211-282J17.13-RELATED hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104;cell cycle#GO:0007049;macromolecule localization#GO:0033036;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012991.1|UniProtKB=W5N5V1 W5N5V1 PTHR24213:SF18 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;lamellipodium assembly#GO:0030032;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 actomyosin#GO:0042641;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stress fiber#GO:0001725;intracellular anatomical structure#GO:0005622;actin filament bundle#GO:0032432;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Axon guidance mediated by netrin#P00009>Ablim#P00358 LEPOC|Ensembl=ENSLOCG00000005966.1|UniProtKB=W5MFR8 W5MFR8 PTHR24012:SF686 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 1 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;regulation of mRNA splicing, via spliceosome#GO:0048024;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002356.1|UniProtKB=W5M301 W5M301 PTHR11537:SF88 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNG1 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;metal ion transport#GO:0030001;action potential#GO:0001508;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000013664.1|UniProtKB=W5N895 W5N895 PTHR45976:SF3 ARMADILLO SEGMENT POLARITY PROTEIN JUNCTION PLAKOGLOBIN protein phosphatase binding#GO:0019903;transcription coactivator activity#GO:0003713;cell adhesion molecule binding#GO:0050839;transcription coregulator activity#GO:0003712;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of biosynthetic process#GO:0009891;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;cell adhesion#GO:0007155;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;nucleus#GO:0005634;cell-cell junction#GO:0005911;membrane#GO:0016020;adherens junction#GO:0005912;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Alzheimer disease-presenilin pathway#P00004>gammacatenin#P00153 LEPOC|Ensembl=ENSLOCG00000006503.1|UniProtKB=W5MHJ6 W5MHJ6 PTHR15494:SF0 CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514 LEPOC|Ensembl=ENSLOCG00000000920.1|UniProtKB=W5LY18 W5LY18 PTHR24232:SF85 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008836.1|UniProtKB=W5MQU5 W5MQU5 PTHR46059:SF3 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 2 glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;cellular process#GO:0009987;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001016.1|UniProtKB=W5LYD5 W5LYD5 PTHR12081:SF43 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000008903.1|UniProtKB=W5MR31 W5MR31 PTHR22811:SF40 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 1 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization#GO:0016043;Golgi organization#GO:0007030;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256 intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737 membrane traffic protein#PC00150;vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000009556.1|UniProtKB=W5MTH1 W5MTH1 PTHR14058:SF5 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 1 binding#GO:0005488;peptide binding#GO:0042277 cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage response#GO:0006974;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cellular response to stress#GO:0033554;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126;Alzheimer disease-amyloid secretase pathway#P00003>Fe65#P00087 LEPOC|Ensembl=ENSLOCG00000017437.1|UniProtKB=W5NLN3 W5NLN3 PTHR11984:SF50 CONNEXIN GAP JUNCTION DELTA-2 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cell communication#GO:0007154;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;regulation of biological process#GO:0050789 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell junction#GO:0030054 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000016477.1|UniProtKB=W5NI95 W5NI95 PTHR15572:SF2 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 BRD4-INTERACTING CHROMATIN-REMODELING COMPLEX-ASSOCIATED PROTEIN-LIKE positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000007377.1|UniProtKB=W5MKN8 W5MKN8 PTHR24054:SF28 CASEIN KINASE II SUBUNIT ALPHA NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 response to stress#GO:0006950;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459 LEPOC|Ensembl=ENSLOCG00000016601.1|UniProtKB=W5NIP4 W5NIP4 PTHR15644:SF2 OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1 OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000014021.1|UniProtKB=W5N9H4 W5N9H4 PTHR15382:SF3 CTG4A-RELATED PROTEIN CANOPY HOMOLOG 4 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 LEPOC|Ensembl=ENSLOCG00000006008.1|UniProtKB=W5MFV1 W5MFV1 PTHR12289:SF30 METAXIN RELATED METAXIN-3 mitochondrion organization#GO:0007005;membrane organization#GO:0061024;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668 cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003210.1|UniProtKB=W5M5Y6 W5M5Y6 PTHR14627:SF0 TRANSMEMBRANE PROTEIN 204 TRANSMEMBRANE PROTEIN 204 regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009285.1|UniProtKB=W5MSH0 W5MSH0 PTHR12000:SF21 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;catabolic process#GO:0009056;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000018207.1|UniProtKB=W5NNU9 W5NNU9 PTHR26451:SF886 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004509.1|UniProtKB=W5MAI4 W5MAI4 PTHR10529:SF342 AP COMPLEX SUBUNIT MU AP-3 COMPLEX SUBUNIT MU-1 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endocytosis#GO:0006897;postsynaptic neurotransmitter receptor internalization#GO:0098884;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;regulation of biological quality#GO:0065008;post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;receptor internalization#GO:0031623;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;receptor-mediated endocytosis#GO:0006898;intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034 membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;AP-type membrane coat adaptor complex#GO:0030119 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014970.1|UniProtKB=W5NCS3 W5NCS3 PTHR11685:SF475 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012123.1|UniProtKB=W5N2Q7 W5N2Q7 PTHR15379:SF2 CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1 CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1 regulation of growth#GO:0040008;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell growth#GO:0030308;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell growth#GO:0001558;regulation of cellular component organization#GO:0051128;negative regulation of cellular process#GO:0048523 LEPOC|Ensembl=ENSLOCG00000000165.1|UniProtKB=W5LVM6 W5LVM6 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013306.1|UniProtKB=W5N6Z1 W5N6Z1 PTHR12552:SF13 OLIGOPHRENIN 1 DCC-INTERACTING PROTEIN 13-ALPHA enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000010034.1|UniProtKB=W5MV68 W5MV68 PTHR21330:SF1 E3 SUMO-PROTEIN LIGASE NSE2 E3 SUMO-PROTEIN LIGASE NSE2 SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;protein modification by small protein conjugation or removal#GO:0070647;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;condensed chromosome#GO:0000793;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007981.1|UniProtKB=W5MMV0 W5MMV0 PTHR22767:SF3 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000011015.1|UniProtKB=W5MYR3 W5MYR3 PTHR24408:SF34 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 48 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000006517.1|UniProtKB=W5MHL7 W5MHL7 PTHR11043:SF2 ZETA-COAT PROTEIN COATOMER SUBUNIT ZETA-1 intra-Golgi vesicle-mediated transport#GO:0006891;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;macromolecule localization#GO:0033036;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;vesicle coat#GO:0030120;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014978.1|UniProtKB=W5NCT0 W5NCT0 PTHR46099:SF4 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ENDOTHELIN RECEPTOR B SUBTYPE 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;developmental pigmentation#GO:0048066;cellular process#GO:0009987;signal transduction#GO:0007165;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;pigmentation#GO:0043473 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 Endothelin signaling pathway#P00019>ET-RA/B#P00580 LEPOC|Ensembl=ENSLOCG00000015089.1|UniProtKB=W5ND67 W5ND67 PTHR24418:SF197 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FES_FPS catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672 response to external stimulus#GO:0009605;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;taxis#GO:0042330;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell adhesion#GO:0007155;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;chemotaxis#GO:0006935;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 Axon guidance mediated by semaphorins#P00007>Fes#P00332 LEPOC|Ensembl=ENSLOCG00000009583.1|UniProtKB=W5MTL8 W5MTL8 PTHR48051:SF39 FAMILY NOT NAMED LEUCINE RICH REPEAT CONTAINING 27 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015191.1|UniProtKB=W5NDI2 W5NDI2 PTHR24073:SF1089 DRAB5-RELATED RAS-RELATED PROTEIN RAB-6A-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 localization within membrane#GO:0051668;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;intra-Golgi vesicle-mediated transport#GO:0006891;protein localization to membrane#GO:0072657;cytosolic transport#GO:0016482;protein localization to organelle#GO:0033365;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;protein localization to Golgi apparatus#GO:0034067;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of protein localization#GO:0045184;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000010131.1|UniProtKB=W5MVI7 W5MVI7 PTHR20968:SF4 ILGF DOMAIN-CONTAINING PROTEIN RELAXIN 3 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;positive regulation of signaling#GO:0023056 LEPOC|Ensembl=ENSLOCG00000005509.1|UniProtKB=W5ME44 W5ME44 PTHR24073:SF185 DRAB5-RELATED RAS-RELATED PROTEIN RAB-14 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;lytic vacuole organization#GO:0080171;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;phagolysosome assembly#GO:0001845;intracellular transport#GO:0046907;phagocytosis#GO:0006909;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome organization#GO:0007040;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;post-Golgi vesicle-mediated transport#GO:0006892;vacuole organization#GO:0007033;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;organelle assembly#GO:0070925;cytosolic transport#GO:0016482;endocytosis#GO:0006897;Golgi to endosome transport#GO:0006895;cellular component organization#GO:0016043 endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;vesicle#GO:0031982;intracellular vesicle#GO:0097708 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000018170.1|UniProtKB=W5NNR2 W5NNR2 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 519 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015486.1|UniProtKB=W5NEK2 W5NEK2 PTHR32194:SF2 METALLOPROTEASE TLDD PROTEASOME SUBUNIT BETA TYPE-1 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;proteasome complex#GO:0000502;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368 metalloprotease#PC00153 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000017127.1|UniProtKB=W5NKK6 W5NKK6 PTHR13674:SF3 GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN PROTEIN FAM162B LEPOC|Ensembl=ENSLOCG00000004195.1|UniProtKB=W5M9F9 W5M9F9 PTHR24264:SF15 TRYPSIN-RELATED TRYPSIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000015928.1|UniProtKB=W5NG51 W5NG51 PTHR13267:SF3 ZINC FINGER PROTEIN 277 ZINC FINGER PROTEIN 277 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000002992.1|UniProtKB=W5M5B6 W5M5B6 PTHR11731:SF21 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED INACTIVE DIPEPTIDYL PEPTIDASE 10 potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;ion channel regulator activity#GO:0099106;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;regulation of monoatomic cation transmembrane transport#GO:1904062;macromolecule metabolic process#GO:0043170;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;proteolysis#GO:0006508;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000007515.1|UniProtKB=W5ML62 W5ML62 PTHR12125:SF12 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX PROTEIN 44 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001569.1|UniProtKB=W5M086 W5M086 PTHR23049:SF36 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 10 myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;mitochondrion#GO:0005739 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000015073.1|UniProtKB=W5ND44 W5ND44 PTHR10182:SF18 CALCIUM-BINDING PROTEIN 39-RELATED CALCIUM BINDING PROTEIN 39, LIKE 1 ISOFORM X1 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 LEPOC|Ensembl=ENSLOCG00000012572.1|UniProtKB=W5N4B7 W5N4B7 PTHR11085:SF1 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-7 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407;transferase activity#GO:0016740;deacylase activity#GO:0160215;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;acyltransferase activity#GO:0016746 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;response to stimulus#GO:0050896 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 LEPOC|Ensembl=ENSLOCG00000006280.1|UniProtKB=W5MGS6 W5MGS6 PTHR12452:SF7 42-9-9 PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;response to tumor necrosis factor#GO:0034612;signal transduction#GO:0007165;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000021.1|UniProtKB=W5LV66 W5LV66 PTHR12027:SF84 WNT RELATED PROTEIN WNT-9B frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515 cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell fate commitment#GO:0045165;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 LEPOC|Ensembl=ENSLOCG00000017630.1|UniProtKB=W5NM76 W5NM76 PTHR22750:SF13 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 4 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011306.1|UniProtKB=W5MZT6 W5MZT6 PTHR46493:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009099.1|UniProtKB=W5MRT3 W5MRT3 PTHR22799:SF8 TETRANECTIN-RELATED COLLECTIN SUBFAMILY MEMBER 10 ossification#GO:0001503;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012993.1|UniProtKB=W5N5U4 W5N5U4 PTHR43107:SF23 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN ZGC:158482 ISOFORM X1 carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;catalytic activity#GO:0003824 localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;import into cell#GO:0098657;establishment of localization#GO:0051234;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;organic acid transport#GO:0015849;lipid metabolic process#GO:0006629;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid transport#GO:0006869;macromolecule localization#GO:0033036;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014008.1|UniProtKB=W5N9H3 W5N9H3 PTHR10814:SF24 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 3 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 LEPOC|Ensembl=ENSLOCG00000006049.1|UniProtKB=W5MFZ5 W5MFZ5 PTHR24412:SF215 KELCH PROTEIN KELCH-LIKE PROTEIN 24 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018297.1|UniProtKB=W5NP39 W5NP39 PTHR11462:SF37 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JUNB transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;response to steroid hormone#GO:0048545;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of transcription by RNA polymerase II#GO:0045944;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;response to lipid#GO:0033993;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>JUN#P06757;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838 LEPOC|Ensembl=ENSLOCG00000014059.1|UniProtKB=W5N9M4 W5N9M4 PTHR13650:SF2 SPATACSIN SPATACSIN cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle transport#GO:0048489;synaptic signaling#GO:0099536;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;establishment of organelle localization#GO:0051656;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;microtubule-based transport#GO:0099111;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular localization#GO:0051641;vesicle localization#GO:0051648;axon development#GO:0061564;axo-dendritic transport#GO:0008088;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;intracellular transport#GO:0046907;neurogenesis#GO:0022008;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;chemical synaptic transmission#GO:0007268;microtubule-based movement#GO:0007018;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154 cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425 LEPOC|Ensembl=ENSLOCG00000000741.1|UniProtKB=W5LXG5 W5LXG5 PTHR10462:SF61 GLYCOSYLTRANSFERASE-RELATED GLOBOSIDE ALPHA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1-RELATED glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000010824.1|UniProtKB=W5MY11 W5MY11 PTHR11100:SF7 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-1, MEMBRANE-BOUND ISOFORM signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;peripheral nervous system development#GO:0007422;signaling#GO:0023052;regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;intracellular signal transduction#GO:0035556;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;signal transduction#GO:0007165;nervous system development#GO:0007399;head development#GO:0060322;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 LEPOC|Ensembl=ENSLOCG00000014424.1|UniProtKB=W5NAU4 W5NAU4 PTHR45704:SF11 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE LEPOC|Ensembl=ENSLOCG00000013698.1|UniProtKB=W5N8D2 W5N8D2 PTHR11599:SF46 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-6 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008933.1|UniProtKB=W5MR70 W5MR70 PTHR11918:SF45 RADICAL SAM PROTEINS THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005076.1|UniProtKB=W5MCK3 W5MCK3 PTHR45722:SF2 60S RIBOSOMAL PROTEIN L35 LARGE RIBOSOMAL SUBUNIT PROTEIN UL29 RNA binding#GO:0003723;structural molecule activity#GO:0005198;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000002217.1|UniProtKB=W5M2H3 W5M2H3 PTHR13947:SF11 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLASPARTATE SYNTHETASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000007103.1|UniProtKB=W5MJP1 W5MJP1 PTHR11309:SF23 FRIZZLED FRIZZLED-4 Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;retina development in camera-type eye#GO:0060041;sensory system development#GO:0048880;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;vasculature development#GO:0001944;sensory organ development#GO:0007423;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;circulatory system development#GO:0072359;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;visual system development#GO:0150063;signaling#GO:0023052;non-canonical Wnt signaling pathway#GO:0035567;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular response to stimulus#GO:0051716;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 LEPOC|Ensembl=ENSLOCG00000006060.1|UniProtKB=W5MG30 W5MG30 PTHR12455:SF0 NUCLEOLAR COMPLEX PROTEIN 4 NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000853.1|UniProtKB=W5LXU0 W5LXU0 PTHR24247:SF244 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 7 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227 G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012130.1|UniProtKB=W5N2R4 W5N2R4 PTHR24412:SF507 KELCH PROTEIN KELCH-LIKE PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010360.1|UniProtKB=W5MWF3 W5MWF3 PTHR11618:SF4 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 LEPOC|Ensembl=ENSLOCG00000008896.1|UniProtKB=W5MR22 W5MR22 PTHR12419:SF9 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 4 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843 negative regulation of cell communication#GO:0010648;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of response to cytokine stimulus#GO:0060761;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cytokine-mediated signaling pathway#GO:0001959;regulation of innate immune response#GO:0045088;negative regulation of cytokine-mediated signaling pathway#GO:0001960;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;regulation of response to cytokine stimulus#GO:0060759 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000015522.1|UniProtKB=W5NEP3 W5NEP3 PTHR46544:SF2 EXTRACELLULAR MATRIX PROTEIN 2-RELATED EXTRACELLULAR MATRIX PROTEIN 2 ISOFORM X1-RELATED protein-containing complex binding#GO:0044877;heparin binding#GO:0008201;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;collagen binding#GO:0005518;glycosaminoglycan binding#GO:0005539 extracellular structure organization#GO:0043062;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;cellular process#GO:0009987;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 LEPOC|Ensembl=ENSLOCG00000016597.1|UniProtKB=W5NIN9 W5NIN9 PTHR31017:SF2 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED DENN DOMAIN-CONTAINING PROTEIN 11 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000015186.1|UniProtKB=W5NDH7 W5NDH7 PTHR10414:SF79 ETHANOLAMINEPHOSPHOTRANSFERASE CHOLINEPHOSPHOTRANSFERASE 1 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009866.1|UniProtKB=W5MUJ9 W5MUJ9 PTHR10218:SF364 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;action potential#GO:0001508;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991 G-protein#PC00020;heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Endothelin signaling pathway#P00019>Gq#P00586;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Wnt signaling pathway#P00057>Galpha#P01451;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gqalpha#P05927 LEPOC|Ensembl=ENSLOCG00000008668.1|UniProtKB=W5MQB1 W5MQB1 PTHR11339:SF396 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED SCO-SPONDIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000000072.1|UniProtKB=W5LVC4 W5LVC4 PTHR36527:SF8 OS01G0282866 PROTEIN TUBULIN_FTSZ GTPASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002117.1|UniProtKB=W5M253 W5M253 PTHR24068:SF116 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>UbcH8#P01223;Parkinson disease#P00049>UbcH7#P01224 LEPOC|Ensembl=ENSLOCG00000002627.1|UniProtKB=W5M3Y9 W5M3Y9 PTHR19878:SF7 AUTOPHAGY PROTEIN 16-LIKE PROTEIN ATG16L2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;metabolic process#GO:0008152;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;autophagosome#GO:0005776;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000016876.1|UniProtKB=W5NJQ1 W5NJQ1 PTHR12668:SF11 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14A membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000013795.1|UniProtKB=W5N8Q3 W5N8Q3 PTHR48153:SF6 UFM1-SPECIFIC PROTEASE 2 UFM1-SPECIFIC PROTEASE 2 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016807.1|UniProtKB=W5NJG5 W5NJG5 PTHR10344:SF5 THYMIDYLATE KINASE UMP-CMP KINASE 2, MITOCHONDRIAL phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;nucleoside diphosphate metabolic process#GO:0009132;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;nucleotide kinase#PC00172;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000011213.1|UniProtKB=W5MZH2 W5MZH2 PTHR14949:SF53 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 VON WILLEBRAND FACTOR D AND EGF DOMAIN-CONTAINING PROTEIN signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000005875.1|UniProtKB=W5MFD6 W5MFD6 PTHR24253:SF72 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 56 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001859.1|UniProtKB=W5M194 W5M194 PTHR46908:SF10 CUBILIN-LIKE PROTEIN TUMOR NECROSIS FACTOR-INDUCIBLE GENE 6 PROTEIN regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to stress#GO:0080134;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;negative regulation of inflammatory response#GO:0050728;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;negative regulation of defense response#GO:0031348 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007249.1|UniProtKB=W5MK65 W5MK65 PTHR10984:SF85 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000014281.1|UniProtKB=W5NAC3 W5NAC3 PTHR11769:SF19 HYALURONIDASE HYALURONIDASE-3 glycosaminoglycan catabolic process#GO:0006027;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056 secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000009457.1|UniProtKB=W5MT40 W5MT40 PTHR46014:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000002433.1|UniProtKB=W5M395 W5M395 EIF3I PTHR19877:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000016703.1|UniProtKB=W5NJ25 W5NJ25 PTHR24060:SF160 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 3 transmembrane signaling receptor activity#GO:0004888;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell surface receptor signaling pathway#GO:0007166;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Ionotropic glutamate receptor pathway#P00037>mGluR 2/3#P01014;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Metabotropic glutamate receptor group II pathway#P00040>mGluR2/3#P01048 LEPOC|Ensembl=ENSLOCG00000015997.1|UniProtKB=W5NGE4 W5NGE4 PTHR13630:SF1 GAMMA-SECRETASE-ACTIVATING PROTEIN GAMMA-SECRETASE-ACTIVATING PROTEIN regulation of cellular process#GO:0050794;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247 Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006735.1|UniProtKB=W5MIC6 W5MIC6 PTHR10194:SF96 RAS GTPASE-ACTIVATING PROTEINS RAS PROTEIN ACTIVATOR LIKE-3 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000008971.1|UniProtKB=W5MRC2 W5MRC2 PTHR10574:SF292 NETRIN/LAMININ-RELATED NETRIN-3 anatomical structure development#GO:0048856;system development#GO:0048731;axon guidance#GO:0007411;axon development#GO:0061564;tissue development#GO:0009888;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;dendrite development#GO:0016358;neuron development#GO:0048666;axonogenesis#GO:0007409;neuron projection development#GO:0031175;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 LEPOC|Ensembl=ENSLOCG00000001614.1|UniProtKB=W5M0E8 W5M0E8 PTHR16515:SF37 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 2-RELATED transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002089.1|UniProtKB=W5M234 W5M234 PTHR11328:SF29 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN SODIUM-DEPENDENT LYSOPHOSPHATIDYLCHOLINE SYMPORTER 1 monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monocarboxylic acid transmembrane transporter activity#GO:0008028;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;system process#GO:0003008;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;multicellular organismal process#GO:0032501;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid localization#GO:0010876;circulatory system process#GO:0003013;localization#GO:0051179;fatty acid transport#GO:0015908;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monocarboxylic acid transport#GO:0015718;cellular component organization#GO:0016043;carbohydrate derivative transport#GO:1901264;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000001440.1|UniProtKB=W5LZT1 W5LZT1 PTHR14592:SF2 UNCHARACTERIZED FAM3 PROTEIN FAM3B cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008332.1|UniProtKB=W5MP11 W5MP11 PTHR14119:SF17 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002195.1|UniProtKB=W5M2F0 W5M2F0 PTHR14899:SF0 G KINASE ANCHORING PROTEIN 1 G KINASE-ANCHORING PROTEIN 1 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016160.1|UniProtKB=W5NH07 W5NH07 PTHR23291:SF50 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 4 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000009869.1|UniProtKB=W5MUK2 W5MUK2 PTHR12570:SF7 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MAGNESIUM TRANSPORTER NIPA4 monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;magnesium ion transport#GO:0015693 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000016590.1|UniProtKB=W5NIN1 W5NIN1 PTHR35447:SF1 BH3-INTERACTING DOMAIN DEATH AGONIST BH3-INTERACTING DOMAIN DEATH AGONIST regulation of release of cytochrome c from mitochondria#GO:0090199;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;positive regulation of signaling#GO:0023056;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;regulation of organelle organization#GO:0033043;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular component organization#GO:0051128;regulation of apoptotic process#GO:0042981;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;regulation of apoptotic signaling pathway#GO:2001233;programmed cell death#GO:0012501;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of intrinsic apoptotic signaling pathway#GO:2001242;cell death#GO:0008219;regulation of mitochondrion organization#GO:0010821;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000002205.1|UniProtKB=W5M2H0 W5M2H0 PTHR11188:SF48 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004546.1|UniProtKB=W5MAP7 W5MAP7 PTHR15591:SF14 RUN AND SH3 DOMAIN CONTAINING AP-4 COMPLEX ACCESSORY SUBUNIT RUSC2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006823.1|UniProtKB=W5MIN6 W5MIN6 PTHR33539:SF1 UPF0764 PROTEIN C16ORF89 UPF0764 PROTEIN C16ORF89 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000010655.1|UniProtKB=W5MXF0 W5MXF0 PTHR24300:SF153 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2Y3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906;binding#GO:0005488 response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000016569.1|UniProtKB=W5NIK5 W5NIK5 PTHR28675:SF1 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 molecular function regulator activity#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;regulation of biological process#GO:0050789;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;regulation of signaling#GO:0023051;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000006957.1|UniProtKB=W5MJ52 W5MJ52 PTHR23041:SF82 RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF4 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000009402.1|UniProtKB=W5MSW0 W5MSW0 PTHR24067:SF154 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G2 ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;response to chemical#GO:0042221;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;ERAD pathway#GO:0036503;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>Ubc7#P01220 LEPOC|Ensembl=ENSLOCG00000011218.1|UniProtKB=W5MZH0 W5MZH0 PTHR12080:SF125 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 intracellular protein localization#GO:0008104;localization#GO:0051179;cell communication#GO:0007154;immune system process#GO:0002376;protein localization to cell junction#GO:1902414;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;regulation of biological process#GO:0050789;macromolecule localization#GO:0033036 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012055.1|UniProtKB=W5N2G9 W5N2G9 PTHR10625:SF36 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 3 deacylase activity#GO:0160215;catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325 nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654 Wnt signaling pathway#P00057>Histone deacetylase#P01472 LEPOC|Ensembl=ENSLOCG00000011278.1|UniProtKB=W5MZQ6 W5MZQ6 PTHR47219:SF13 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE RUN AND TBC1 DOMAIN-CONTAINING PROTEIN 3 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000003269.1|UniProtKB=W5M652 W5M652 PTHR12308:SF36 ANOCTAMIN ANOCTAMIN phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303 lipid transport#GO:0006869;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000005094.1|UniProtKB=W5MCM8 W5MCM8 PTHR23340:SF0 ARGININE/SERINE RICH SPLICING FACTOR SF4/14 SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000000926.1|UniProtKB=W5LY27 W5LY27 PTHR10656:SF35 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682 regulation of double-strand break repair via homologous recombination#GO:0010569;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;regulation of DNA metabolic process#GO:0051052;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;positive regulation of response to external stimulus#GO:0032103;negative regulation of double-strand break repair via homologous recombination#GO:2000042;positive regulation of cytokine production#GO:0001819;regulation of response to biotic stimulus#GO:0002831;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;response to nitrogen compound#GO:1901698;cellular response to nitrogen compound#GO:1901699;negative regulation of DNA metabolic process#GO:0051053;activation of innate immune response#GO:0002218;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of innate immune response#GO:0045089;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;response to stimulus#GO:0050896;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of DNA recombination#GO:0045910;positive regulation of type I interferon production#GO:0032481;cellular response to stimulus#GO:0051716;regulation of double-strand break repair#GO:2000779;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of response to biotic stimulus#GO:0002833;negative regulation of cellular process#GO:0048523;positive regulation of immune response#GO:0050778;DNA damage response#GO:0006974;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000017408.1|UniProtKB=W5NLK4 W5NLK4 PTHR24409:SF451 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 431-LIKE DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000017407.1|UniProtKB=W5NLK3 W5NLK3 PTHR10704:SF3 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;amino sugar metabolic process#GO:0006040 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003123.1|UniProtKB=W5M5L9 W5M5L9 PTHR11640:SF164 NEPHRIN OPIOID BINDING PROTEIN_CELL ADHESION MOLECULE LIKE protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000003498.1|UniProtKB=W5M6Z0 W5M6Z0 PTHR47977:SF33 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-27B nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;exocytosis#GO:0006887;transport#GO:0006810;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532;cellular process#GO:0009987;localization#GO:0051179;regulation of secretion#GO:0051046;secretion#GO:0046903;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;positive regulation of secretion#GO:0051047;regulation of cellular process#GO:0050794;export from cell#GO:0140352;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;Golgi apparatus#GO:0005794;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000011317.1|UniProtKB=W5MZV4 W5MZV4 PTHR11636:SF68 POU DOMAIN POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000006532.1|UniProtKB=W5MHN3 W5MHN3 PTHR10857:SF2 COPINE COPINE-1 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of cytokine-mediated signaling pathway#GO:0001961;response to calcium ion#GO:0051592;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of response to cytokine stimulus#GO:0060759;regulation of cytokine-mediated signaling pathway#GO:0001959;response to metal ion#GO:0010038;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000008077.1|UniProtKB=W5MN54 W5MN54 PTHR12276:SF48 EPSIN/ENT-RELATED EPSIN-1 phospholipid binding#GO:0005543;binding#GO:0005488;clathrin binding#GO:0030276;lipid binding#GO:0008289;protein binding#GO:0005515 transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vesicle coat#GO:0030120;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005915.1|UniProtKB=W5MFI9 W5MFI9 PTHR31809:SF0 BUD13 HOMOLOG BUD13 HOMOLOG macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016525.1|UniProtKB=W5NIF2 W5NIF2 PTHR15446:SF17 UROPLAKIN III UROPLAKIN-3A transport#GO:0006810;nitrogen compound transport#GO:0071705;fluid transport#GO:0042044;establishment of localization#GO:0051234;water transport#GO:0006833;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015662.1|UniProtKB=W5NF71 W5NF71 PTHR10553:SF2 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U12-type spliceosomal complex#GO:0005689;nucleus#GO:0005634;U1 snRNP#GO:0005685;ribonucleoprotein granule#GO:0035770;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;precatalytic spliceosome#GO:0071011;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2-type prespliceosome#GO:0071004;cytoplasmic ribonucleoprotein granule#GO:0036464;U2 snRNP#GO:0005686;P granule#GO:0043186;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;SMN-Sm protein complex#GO:0034719;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000012097.1|UniProtKB=W5N2M5 W5N2M5 PTHR21093:SF2 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1C LEPOC|Ensembl=ENSLOCG00000002803.1|UniProtKB=W5M4L7 W5M4L7 PTHR19307:SF12 TUMOR PROTEIN D52 TUMOR PROTEIN D52 biological regulation#GO:0065007;hemopoiesis#GO:0030097;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;B cell activation#GO:0042113;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;mononuclear cell differentiation#GO:1903131;leukocyte activation#GO:0045321;positive regulation of cell population proliferation#GO:0008284;leukocyte differentiation#GO:0002521;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;lymphocyte differentiation#GO:0030098;cell activation#GO:0001775;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013086.1|UniProtKB=W5N661 W5N661 PTHR11551:SF6 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 1 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 PI3 kinase pathway#P00048>IGFBP1#G01543 LEPOC|Ensembl=ENSLOCG00000013821.1|UniProtKB=W5N8T8 W5N8T8 PTHR11802:SF3 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine-type peptidase activity#GO:0008236 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000013583.1|UniProtKB=W5N7Z3 W5N7Z3 PTHR43829:SF6 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-9 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;carbohydrate transmembrane transporter activity#GO:0015144;channel activity#GO:0015267 carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;water transport#GO:0006833;fluid transport#GO:0042044;organic hydroxy compound transport#GO:0015850;transport#GO:0006810;carbohydrate transport#GO:0008643 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003701.1|UniProtKB=W5M7R7 W5M7R7 PTHR24403:SF115 ZINC FINGER PROTEIN ZINC FINGER PROTEIN ZFAT double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003868.1|UniProtKB=W5M8C2 W5M8C2 PTHR46449:SF5 ZGC:158260 FAMILY WITH SEQUENCE SIMILARITY 47 MEMBER E transcription by RNA polymerase II#GO:0006366;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;biological regulation#GO:0065007;positive regulation of biosynthetic process#GO:0009891;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;transcription initiation-coupled chromatin remodeling#GO:0045815;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;DNA-templated transcription initiation#GO:0006352;chromatin remodeling#GO:0006338 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000009570.1|UniProtKB=W5MTL3 W5MTL3 PTHR45620:SF6 PDF RECEPTOR-LIKE PROTEIN-RELATED GROWTH HORMONE-RELEASING HORMONE RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004383.1|UniProtKB=W5MA24 W5MA24 PTHR14076:SF3 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;coreceptor activity#GO:0015026 localization within membrane#GO:0051668;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;protein transport#GO:0015031;cellular localization#GO:0051641;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;protein localization to membrane#GO:0072657;signaling#GO:0023052;endocytosis#GO:0006897;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;protein localization to cell periphery#GO:1990778;calcium ion transport#GO:0006816;import into cell#GO:0098657;cellular process#GO:0009987;signal transduction#GO:0007165;establishment of protein localization#GO:0045184;response to hormone#GO:0009725;receptor internalization#GO:0031623;vesicle-mediated transport#GO:0016192;response to chemical#GO:0042221 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000885.1|UniProtKB=W5LXX7 W5LXX7 PTHR13195:SF0 PSEUDOURIDINE SYNTHASE-RELATED PSEUDOURIDYLATE SYNTHASE TRUB2, MITOCHONDRIAL catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;post-transcriptional regulation of gene expression#GO:0010608;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;macromolecule modification#GO:0043412;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;positive regulation of macromolecule metabolic process#GO:0010604;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;mRNA modification#GO:0016556;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA modification#GO:0009451;positive regulation of protein metabolic process#GO:0051247 mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000007917.1|UniProtKB=W5MMK6 W5MMK6 PTHR21029:SF12 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G PROTEIN SIGNALING 7-BINDING PROTEIN cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;nucleus#GO:0005634;neuron projection#GO:0043005;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006527.1|UniProtKB=W5MHM4 W5MHM4 PTHR14744:SF15 N-ALPHA-ACETYLTRANSFERASE 60 N-ALPHA-ACETYLTRANSFERASE 60 acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;chromosome segregation#GO:0007059 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 acetyltransferase#PC00038;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000013647.1|UniProtKB=W5N873 W5N873 PTHR24221:SF402 ATP-BINDING CASSETTE SUB-FAMILY B IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000014728.1|UniProtKB=W5NBX5 W5NBX5 PTHR14939:SF10 F-BOX ONLY PROTEIN 22 F-BOX ONLY PROTEIN 22 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cell differentiation#GO:0045595;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;regulation of cell development#GO:0060284;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000011277.1|UniProtKB=W5MZQ2 W5MZQ2 PTHR23430:SF47 HISTONE H2A HISTONE H2A.Z structural molecule activity#GO:0005198 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;protein-DNA complex#GO:0032993;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008046.1|UniProtKB=W5MN13 W5MN13 PTHR15853:SF2 THIOREDOXIN-RELATED THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 2 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;nervous system development#GO:0007399;head development#GO:0060322;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;brain development#GO:0007420 cytoplasm#GO:0005737;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;organelle membrane contact site#GO:0044232;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016785.1|UniProtKB=W5NJD7 W5NJD7 PTHR21676:SF1 PROTEIN STUM PROTEIN STUM HOMOLOG LEPOC|Ensembl=ENSLOCG00000003775.1|UniProtKB=W5M7Z1 W5M7Z1 PTHR14132:SF12 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA PHOSPHOLEMMAN ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of cellular process#GO:0050794;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;regulation of monoatomic ion transmembrane transport#GO:0034765;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000011027.1|UniProtKB=W5MYS3 W5MYS3 PTHR17408:SF7 HISTONE RNA HAIRPIN-BINDING PROTEIN HISTONE RNA HAIRPIN-BINDING PROTEIN RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 transport#GO:0006810;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;establishment of localization#GO:0051234;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;localization#GO:0051179;nucleic acid transport#GO:0050657;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;establishment of RNA localization#GO:0051236;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013203.1|UniProtKB=W5N6N9 W5N6N9 PTHR45615:SF24 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-10 ATP-dependent activity#GO:0140657;actin binding#GO:0003779;actin filament binding#GO:0051015;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of cell shape#GO:0008360;cell division#GO:0051301;cell cycle#GO:0007049;cellular component organization#GO:0016043;regulation of developmental process#GO:0050793;actomyosin structure organization#GO:0031032;mitotic cell cycle#GO:0000278;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;actin filament-based process#GO:0030029;cytokinesis#GO:0000910;regulation of biological quality#GO:0065008;cytoskeleton-dependent cytokinesis#GO:0061640;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603 actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 LEPOC|Ensembl=ENSLOCG00000003422.1|UniProtKB=W5M6N9 W5M6N9 PTHR22957:SF207 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 10B molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000010198.1|UniProtKB=W5MVS8 W5MVS8 PTHR34290:SF3 SI:CH73-390P7.2 THIOL-DISULPHIDE OXIDOREDUCTASE DCC catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035 LEPOC|Ensembl=ENSLOCG00000000980.1|UniProtKB=W5LY93 W5LY93 PTHR11993:SF48 NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055;NADH dehydrogenase activity#GO:0003954 aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001518.1|UniProtKB=W5M026 W5M026 PTHR18847:SF0 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleocytoplasmic transport#GO:0006913;RNA splicing, via transesterification reactions#GO:0000375;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid transport#GO:0050657;localization#GO:0051179;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;mRNA transport#GO:0051028;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule localization#GO:0033036;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA processing#GO:0006397;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017903.1|UniProtKB=W5NMZ7 W5NMZ7 PTHR12151:SF2 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER CYTOCHROME C OXIDASE ASSEMBLY FACTOR SCO2 mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 metabolite interconversion enzyme#PC00262;oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007412.1|UniProtKB=W5MKT9 W5MKT9 PTHR22850:SF82 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP7 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;PcG protein complex#GO:0031519;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000004330.1|UniProtKB=W5M9W7 W5M9W7 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011986.1|UniProtKB=W5N281 W5N281 PTHR23210:SF26 ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000004573.1|UniProtKB=W5MAR0 W5MAR0 PTHR11481:SF132 IMMUNOGLOBULIN FC RECEPTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;immune response#GO:0006955;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010828.1|UniProtKB=W5MY09 W5MY09 PTHR44668:SF2 FAMILY NOT NAMED DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7C LEPOC|Ensembl=ENSLOCG00000016129.1|UniProtKB=W5NGX3 W5NGX3 PTHR10241:SF22 LETHAL 2 GIANT LARVAE PROTEIN SYNTAXIN-BINDING PROTEIN 5 cytoskeletal protein binding#GO:0008092;enzyme activator activity#GO:0008047;SNARE binding#GO:0000149;myosin binding#GO:0017022;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;binding#GO:0005488;molecular function activator activity#GO:0140677;syntaxin binding#GO:0019905;protein binding#GO:0005515;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;localization within membrane#GO:0051668;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;secretion#GO:0046903;establishment of localization#GO:0051234;secretion by cell#GO:0032940;exocytosis#GO:0006887;post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport to the plasma membrane#GO:0098876 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000015218.1|UniProtKB=W5NDL9 W5NDL9 PTHR24416:SF552 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cell migration#GO:0016477 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VEGFR-2#P00222;VEGF signaling pathway#P00056>VEGFR-2#P01403 LEPOC|Ensembl=ENSLOCG00000009881.1|UniProtKB=W5MUL8 W5MUL8 PTHR23001:SF7 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 5 binding#GO:0005488;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;translation factor activity#GO:0180051;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;nucleoside-triphosphatase regulator activity#GO:0060589;translation initiation factor binding#GO:0031369;GTPase regulator activity#GO:0030695 metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000001251.1|UniProtKB=W5LZ65 W5LZ65 PTHR16127:SF10 TAXILIN BETA-TAXILIN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018069.1|UniProtKB=W5NNG1 W5NNG1 PTHR11537:SF23 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 2 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215 metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell projection#GO:0042995;neuron projection terminus#GO:0044306;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;main axon#GO:0044304;neuron projection#GO:0043005;presynapse#GO:0098793;transporter complex#GO:1990351;cell junction#GO:0030054;axon terminus#GO:0043679;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000016345.1|UniProtKB=W5NHS5 W5NHS5 PTHR15356:SF0 NEUROTENSIN/NEUROMEDIN N NEUROTENSIN_NEUROMEDIN N binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 axon terminus#GO:0043679;cell junction#GO:0030054;axon#GO:0030424;cell projection#GO:0042995;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;presynapse#GO:0098793;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000009895.1|UniProtKB=W5MUN1 W5MUN1 PTHR24179:SF20 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12A enzyme inhibitor activity#GO:0004857;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;A band#GO:0031672;sarcomere#GO:0030017;membraneless organelle#GO:0043228;I band#GO:0031674;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;Z disc#GO:0030018 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000015953.1|UniProtKB=W5NG83 W5NG83 PTHR10556:SF37 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 animal gross anatomical part developmental process#GO:0160108;reproductive system development#GO:0061458;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of hormone levels#GO:0010817;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;reproductive structure development#GO:0048608;reproductive process#GO:0022414;hormone biosynthetic process#GO:0042446;male sex differentiation#GO:0046661;lipid metabolic process#GO:0006629;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;metabolic process#GO:0008152;development of primary male sexual characteristics#GO:0046546;animal organ development#GO:0048513;steroid biosynthetic process#GO:0006694;multicellular organism development#GO:0007275;cellular process#GO:0009987;sex differentiation#GO:0007548;male gonad development#GO:0008584;gonad development#GO:0008406;biosynthetic process#GO:0009058;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;multicellular organismal process#GO:0032501;hormone metabolic process#GO:0042445 cell body#GO:0044297;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006810.1|UniProtKB=W5MIL3 W5MIL3 PTHR12011:SF454 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G2 ISOFORM X1-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012740.1|UniProtKB=W5N4X1 W5N4X1 ADSSL1 PTHR11846:SF2 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 1 ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;ligase#PC00142 De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890;Wnt signaling pathway#P00057>NFAT Target Genes#G01559 LEPOC|Ensembl=ENSLOCG00000014868.1|UniProtKB=W5NCF2 W5NCF2 PTHR21366:SF14 GLYOXALASE FAMILY PROTEIN GLYOXALASE DOMAIN-CONTAINING PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000004252.1|UniProtKB=W5M9M3 W5M9M3 PTHR13523:SF3 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 2-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000007724.1|UniProtKB=W5MLW7 W5MLW7 PTHR16181:SF29 PROTEIN FAM83A-RELATED PROTEIN FAM83C protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 LEPOC|Ensembl=ENSLOCG00000008907.1|UniProtKB=W5MR38 W5MR38 PTHR46986:SF1 ENDORIBONUCLEASE YBEY, CHLOROPLASTIC ENDORIBONUCLEASE YBEY ISOFORM 1 RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000007955.1|UniProtKB=W5MMQ6 W5MMQ6 PTHR48083:SF35 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE FAMILY MEMBER 10 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000007887.1|UniProtKB=W5MMJ1 W5MMJ1 PTHR21419:SF37 FAMILY NOT NAMED FAMILY WITH SEQUENCE SIMILARITY 234 MEMBER A LEPOC|Ensembl=ENSLOCG00000017946.1|UniProtKB=W5NN40 W5NN40 PTHR10489:SF935 CELL ADHESION MOLECULE RELAXIN FAMILY PEPTIDE RECEPTOR 3.3A3-RELATED cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004758.1|UniProtKB=W5MBF1 W5MBF1 PTHR15622:SF12 WD40 REPEAT PROTEIN WD REPEAT AND SOCS BOX-CONTAINING PROTEIN 1 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446 LEPOC|Ensembl=ENSLOCG00000001935.1|UniProtKB=W5M1H8 W5M1H8 PTHR12935:SF13 GAMMA-GLUTAMYLCYCLOTRANSFERASE GAMMA-GLUTAMYLCYCLOTRANSFERASE A catalytic activity#GO:0003824;lyase activity#GO:0016829 LEPOC|Ensembl=ENSLOCG00000008005.1|UniProtKB=W5MMW5 W5MMW5 PTHR13047:SF0 PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 5 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000000832.1|UniProtKB=W5LXS0 W5LXS0 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 binding#GO:0005488;antigen binding#GO:0003823 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007603.1|UniProtKB=W5MLG4 W5MLG4 PTHR24173:SF29 ANKYRIN REPEAT CONTAINING PHOTORECEPTOR ANKYRIN REPEAT PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005522.1|UniProtKB=W5ME57 W5ME57 PTHR24153:SF0 ESPIN ESPIN-LIKE PROTEIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;system process#GO:0003008;sensory perception of sound#GO:0007605;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;supramolecular fiber organization#GO:0097435;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;actin filament-based process#GO:0030029;nervous system process#GO:0050877 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin-based cell projection#GO:0098858;neuron projection#GO:0043005;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stereocilium#GO:0032420 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000010740.1|UniProtKB=W5MXQ0 W5MXQ0 PTHR44888:SF4 HEPACAM FAMILY MEMBER 2-RELATED HEPACAM FAMILY MEMBER 2 LEPOC|Ensembl=ENSLOCG00000017773.1|UniProtKB=W5NML8 W5NML8 PTHR24237:SF38 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000690.1|UniProtKB=W5LXA6 W5LXA6 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000018109.1|UniProtKB=W5NNK1 W5NNK1 PTHR10494:SF4 BONE MORPHOGENETIC PROTEIN INHIBITOR, NOGGIN NOGGIN molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 regionalization#GO:0003002;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;regulation of BMP signaling pathway#GO:0030510;multicellular organism development#GO:0007275;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;dorsal/ventral pattern formation#GO:0009953;regulation of biological process#GO:0050789;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;system development#GO:0048731;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;pattern specification process#GO:0007389;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004385.1|UniProtKB=W5MA31 W5MA31 PTHR13392:SF6 ATAXIN 1 ATAXIN-1-LIKE chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;nervous system development#GO:0007399;head development#GO:0060322;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;negative regulation of metabolic process#GO:0009892 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016882.1|UniProtKB=W5NJQ9 W5NJQ9 PTHR34988:SF1 PROTEIN, PUTATIVE-RELATED PPC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003556.1|UniProtKB=W5M780 W5M780 PTHR10527:SF5 IMPORTIN BETA IMPORTIN-5 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;cellular localization#GO:0051641 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009226.1|UniProtKB=W5MSB3 W5MSB3 PTHR11255:SF30 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE DELTA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;neutral lipid metabolic process#GO:0006638;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000012890.1|UniProtKB=W5N5F9 W5N5F9 PTHR10024:SF234 SYNAPTOTAGMIN SYNAPTOTAGMIN-15-RELATED protein binding#GO:0005515;molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149 cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;vesicle-mediated transport#GO:0016192;transport#GO:0006810;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of transport#GO:0051049;regulation of localization#GO:0032879;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;localization#GO:0051179 endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000005600.1|UniProtKB=W5MEF3 W5MEF3 PTHR46004:SF1 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383 LEPOC|Ensembl=ENSLOCG00000004019.1|UniProtKB=W5M8U3 W5M8U3 PTHR10336:SF102 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN INACTIVE PHOSPHOLIPASE C-LIKE PROTEIN 1 catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 cell communication#GO:0007154;regulation of signaling#GO:0023051;cell-cell signaling#GO:0007267;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;cellular process#GO:0009987 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530 LEPOC|Ensembl=ENSLOCG00000001191.1|UniProtKB=W5LYY2 W5LYY2 PTHR12620:SF8 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT U2 SMALL NUCLEAR RNA AUXILIARY FACTOR 1 RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000005390.1|UniProtKB=W5MDQ2 W5MDQ2 PTHR24271:SF55 KALLIKREIN-RELATED SERINE PROTEASE 57 serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000012238.1|UniProtKB=W5N364 W5N364 PTHR11347:SF73 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT BETA cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;retina development in camera-type eye#GO:0060041;sensory system development#GO:0048880;multicellular organism development#GO:0007275;animal organ development#GO:0048513;sensory organ development#GO:0007423;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;visual system development#GO:0150063;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;negative regulation of cell communication#GO:0010648;camera-type eye development#GO:0043010;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;plasma membrane region#GO:0098590;ciliary membrane#GO:0060170;plasma membrane#GO:0005886;cilium#GO:0005929;cell projection membrane#GO:0031253;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 phosphodiesterase#PC00185;hydrolase#PC00121 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEalphabeta#P00759 LEPOC|Ensembl=ENSLOCG00000002875.1|UniProtKB=W5M4S4 W5M4S4 PTHR24061:SF0 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017936.1|UniProtKB=W5NN30 W5NN30 PTHR31366:SF2 UPF0739 PROTEIN C1ORF74 UPF0739 PROTEIN C1ORF74 LEPOC|Ensembl=ENSLOCG00000002667.1|UniProtKB=W5M448 W5M448 PTHR45627:SF8 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 9 cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate biosynthetic process#GO:1901293;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;cyclic purine nucleotide metabolic process#GO:0052652;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic nucleotide biosynthetic process#GO:0009190;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 adenylate cyclase#PC00043 GABA-B receptor II signaling#P05731>AC#P05760;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 LEPOC|Ensembl=ENSLOCG00000006471.1|UniProtKB=W5MHF8 W5MHF8 PTHR13723:SF312 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 4 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000003477.1|UniProtKB=W5M6W1 W5M6W1 PTHR12917:SF16 ASPARTYL PROTEASE DDI-RELATED NUCLEAR RECEPTOR-INTERACTING PROTEIN 3 catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013427.1|UniProtKB=W5N7E7 W5N7E7 PTHR15129:SF1 SRC-ASSOCIATED ADAPTOR PROTEIN SRC KINASE-ASSOCIATED PHOSPHOPROTEIN 1 regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of cell adhesion mediated by integrin#GO:0033628;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of cell adhesion#GO:0045785;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of leukocyte cell-cell adhesion#GO:1903039;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;T cell receptor signaling pathway#GO:0050852;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007856.1|UniProtKB=W5MMC7 W5MMC7 PTHR23235:SF29 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP5 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013599.1|UniProtKB=W5N809 W5N809 PTHR23239:SF180 INTERMEDIATE FILAMENT KERATIN 96-RELATED structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;epithelium development#GO:0060429 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000002932.1|UniProtKB=W5M4Z6 W5M4Z6 PTHR24061:SF579 CALCIUM-SENSING RECEPTOR-RELATED OLFACTORY RECEPTOR C FAMILY, U1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006080.1|UniProtKB=W5MG33 W5MG33 PTHR17103:SF10 NEUREXOPHILIN NEUREXOPHILIN-4 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;GABA-ergic synapse#GO:0098982 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015799.1|UniProtKB=W5NFP0 W5NFP0 PTHR12027:SF70 WNT RELATED PROTEIN WNT-16 cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;system development#GO:0048731;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 LEPOC|Ensembl=ENSLOCG00000005708.1|UniProtKB=W5MEU9 W5MEU9 PTHR13293:SF9 AKIRIN-RELATED AKIRIN-1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of metabolic process#GO:0009893;positive regulation of cellular component organization#GO:0051130;positive regulation of cell motility#GO:2000147;positive regulation of response to external stimulus#GO:0032103;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cell motility#GO:2000145;positive regulation of biosynthetic process#GO:0009891;positive regulation of chemotaxis#GO:0050921;regulation of DNA-templated transcription#GO:0006355;regulation of cell projection assembly#GO:0060491;regulation of granulocyte chemotaxis#GO:0071622;regulation of leukocyte migration#GO:0002685;regulation of developmental process#GO:0050793;regulation of response to biotic stimulus#GO:0002831;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;developmental process#GO:0032502;cell migration#GO:0016477;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of innate immune response#GO:0045089;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;tissue regeneration#GO:0042246;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;regulation of chemotaxis#GO:0050920;regulation of biological process#GO:0050789;positive regulation of cell differentiation#GO:0045597;growth#GO:0040007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular component biogenesis#GO:0044089;regulation of response to external stimulus#GO:0032101;regeneration#GO:0031099;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of immune response#GO:0050776;positive regulation of cell projection organization#GO:0031346;regulation of defense response#GO:0031347;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;cell motility#GO:0048870;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of innate immune response#GO:0045088;regulation of plasma membrane bounded cell projection organization#GO:0120035;developmental growth#GO:0048589;regulation of biosynthetic process#GO:0009889;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of locomotion#GO:0040017;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;positive regulation of developmental process#GO:0051094;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of cell migration#GO:0030334;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of primary metabolic process#GO:0080090;negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000016496.1|UniProtKB=W5NIB5 W5NIB5 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000015532.1|UniProtKB=W5NEQ6 W5NEQ6 PTHR34639:SF1 PROTEIN FLATTOP PROTEIN FLATTOP cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030 intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000011448.1|UniProtKB=W5N0D2 W5N0D2 PTHR24222:SF95 ABC TRANSPORTER B FAMILY ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 5 transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010274.1|UniProtKB=W5MW46 W5MW46 PTHR10196:SF69 SUGAR KINASE GLYCEROL KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 carbohydrate kinase#PC00065;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000000019.1|UniProtKB=W5LV63 W5LV63 PTHR46599:SF9 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED 4-RELATED viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000007121.1|UniProtKB=W5MJT8 W5MJT8 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER PANCREATIC ELASTASE catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000007091.1|UniProtKB=W5MJP2 W5MJP2 PTHR12771:SF23 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 1 cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;actin filament-based process#GO:0030029;cell chemotaxis#GO:0060326;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;locomotion#GO:0040011;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;cytoskeleton organization#GO:0007010 plasma membrane#GO:0005886;intracellular protein-containing complex#GO:0140535;guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>ELMO#P00917 LEPOC|Ensembl=ENSLOCG00000006392.1|UniProtKB=W5MH63 W5MH63 PTHR10529:SF370 AP COMPLEX SUBUNIT MU ADAPTOR RELATED PROTEIN COMPLEX 1 SUBUNIT MU 3 ISOFORM X1 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vacuolar transport#GO:0007034;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 membrane protein complex#GO:0098796;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular organelle#GO:0043229;coated membrane#GO:0048475;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011713.1|UniProtKB=W5N188 W5N188 PTHR13342:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR5 RAGULATOR COMPLEX PROTEIN LAMTOR5 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;response to acid chemical#GO:0001101;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;lysosome#GO:0005764 LEPOC|Ensembl=ENSLOCG00000005618.1|UniProtKB=W5MEH2 W5MEH2 PTHR24102:SF6 PHD FINGER PROTEIN PHD FINGER PROTEIN 21A binding#GO:0005488;chromatin binding#GO:0003682 nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000002409.1|UniProtKB=W5M367 W5M367 PTHR10334:SF589 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLI PATHOGENESIS-RELATED 2-RELATED response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007428.1|UniProtKB=W5MKY4 W5MKY4 PTHR45703:SF47 DYNEIN HEAVY CHAIN DYNEIN HEAVY CHAIN 11, AXONEMAL microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000004065.1|UniProtKB=W5M904 W5M904 PTHR43311:SF2 GLUTAMATE--TRNA LIGASE NONDISCRIMINATING GLUTAMYL-TRNA SYNTHETASE EARS2, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 LEPOC|Ensembl=ENSLOCG00000009507.1|UniProtKB=W5MTB0 W5MTB0 PTHR45683:SF18 MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 32 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013663.1|UniProtKB=W5N886 W5N886 PTHR11486:SF27 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 16 signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000007557.1|UniProtKB=W5MLA7 W5MLA7 PTHR28264:SF1 CYTOCHROME C OXIDASE SUBUNIT 7A CYTOCHROME C OXIDASE SUBUNIT 6C transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000010291.1|UniProtKB=W5MW43 W5MW43 PTHR14949:SF25 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 CRYPTIC FAMILY PROTEIN 1B-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;receptor serine/threonine kinase binding#GO:0033612;protein binding#GO:0005515 pattern specification process#GO:0007389;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;determination of left/right symmetry#GO:0007368;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;circulatory system development#GO:0072359;cell differentiation#GO:0030154;left/right pattern formation#GO:0060972;developmental process#GO:0032502;specification of symmetry#GO:0009799;vasculature development#GO:0001944;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;determination of bilateral symmetry#GO:0009855;tube development#GO:0035295;multicellular organismal process#GO:0032501;regionalization#GO:0003002;vasculogenesis#GO:0001570;heart development#GO:0007507 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000011521.1|UniProtKB=W5N0J9 W5N0J9 PTHR42735:SF6 FAMILY NOT NAMED SPHINGOSINE-1-PHOSPHATE LYASE 1 lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid catabolic process#GO:0016042;catabolic process#GO:0009056;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000000002.1|UniProtKB=W5LV45 W5LV45 PTHR31594:SF15 AIG1-TYPE G DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013843.1|UniProtKB=W5N8W7 W5N8W7 PTHR46544:SF1 EXTRACELLULAR MATRIX PROTEIN 2-RELATED EXTRACELLULAR MATRIX PROTEIN 2 protein-containing complex binding#GO:0044877;carbohydrate derivative binding#GO:0097367;collagen binding#GO:0005518;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;heparin binding#GO:0008201 extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;cellular component organization#GO:0016043;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 LEPOC|Ensembl=ENSLOCG00000004949.1|UniProtKB=W5MC57 W5MC57 PTHR45630:SF12 CATION-TRANSPORTING ATPASE-RELATED POLYAMINE-TRANSPORTING ATPASE 13A3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;polyamine transmembrane transporter activity#GO:0015203 localization#GO:0051179;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic ion homeostasis#GO:0050801 late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome membrane#GO:0031902;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000012206.1|UniProtKB=W5N315 W5N315 PTHR43330:SF7 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1 metallopeptidase activity#GO:0008237;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000000033.1|UniProtKB=W5LV80 W5LV80 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007067.1|UniProtKB=W5MJJ9 W5MJJ9 PTHR11220:SF76 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 1-RELATED binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 LEPOC|Ensembl=ENSLOCG00000015727.1|UniProtKB=W5NFF3 W5NFF3 PTHR24056:SF128 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 17 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000009227.1|UniProtKB=W5MS97 W5MS97 PTHR15377:SF7 TRANSCRIPTION ELONGATION REGULATOR 1 TRANSCRIPTION ELONGATION REGULATOR 1 protein binding#GO:0005515;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000005785.1|UniProtKB=W5MF28 W5MF28 PTHR43903:SF1 NEUROLIGIN BILE SALT-ACTIVATED LIPASE protein binding#GO:0005515;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;lipase activity#GO:0016298;signaling receptor binding#GO:0005102;binding#GO:0005488;triacylglycerol lipase activity#GO:0004806;carboxylic ester hydrolase activity#GO:0052689;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;nervous system development#GO:0007399;cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;lipid catabolic process#GO:0016042;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;regulation of biological quality#GO:0065008;ceramide metabolic process#GO:0006672;cellular localization#GO:0051641;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;endocytosis#GO:0006897;synapse assembly#GO:0007416;regulation of body fluid levels#GO:0050878;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;system process#GO:0003008;establishment of localization#GO:0051234;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;lipid metabolic process#GO:0006629;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;biological regulation#GO:0065007;digestion#GO:0007586;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465;system development#GO:0048731;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;secretion#GO:0046903;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;postsynapse organization#GO:0099173;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;catabolic process#GO:0009056;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;synaptic vesicle endocytosis#GO:0048488;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;chemical synaptic transmission#GO:0007268 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;cell surface#GO:0009986 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011977.1|UniProtKB=W5N274 W5N274 PTHR11969:SF6 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000010239.1|UniProtKB=W5MVX9 W5MVX9 PTHR16093:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 120 FAMILY MEMBER INNATE IMMUNITY ACTIVATOR PROTEIN positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;adherens junction organization#GO:0034332;cellular component organization#GO:0016043;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;cell-cell junction organization#GO:0045216;regulation of protein ubiquitination#GO:0031396;cellular component organization or biogenesis#GO:0071840;cell-cell junction maintenance#GO:0045217;regulation of protein modification process#GO:0031399;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;biological regulation#GO:0065007 LEPOC|Ensembl=ENSLOCG00000009903.1|UniProtKB=W5MUN9 W5MUN9 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;cell communication#GO:0007154 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009274.1|UniProtKB=W5MSF4 W5MSF4 PTHR33442:SF1 TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000014051.1|UniProtKB=W5N9L1 W5N9L1 PTHR14624:SF0 DFG10 PROTEIN POLYPRENAL REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;organophosphate metabolic process#GO:0019637;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000016578.1|UniProtKB=W5NIL8 W5NIL8 PTHR11409:SF39 ADENOSINE DEAMINASE ADENOSINE DEAMINASE 2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;adenosine deaminase activity#GO:0004000;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814 glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;adenosine metabolic process#GO:0046085;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;purine nucleobase metabolic process#GO:0006144;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;purine-containing compound metabolic process#GO:0072521;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;purine-containing compound biosynthetic process#GO:0072522;purine nucleoside metabolic process#GO:0042278;nucleoside catabolic process#GO:0009164 cytosol#GO:0005829;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 deaminase#PC00088 LEPOC|Ensembl=ENSLOCG00000016544.1|UniProtKB=W5NIH2 W5NIH2 PTHR21229:SF16 LUNG SEVEN TRANSMEMBRANE RECEPTOR TRANSMEMBRANE PROTEIN 87B transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006133.1|UniProtKB=W5MGA3 W5MGA3 PTHR23412:SF18 STEREOCILIN RELATED OTOANCORIN cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cellular process#GO:0009987 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000388.1|UniProtKB=W5LWB6 W5LWB6 PTHR13531:SF5 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 216 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000004737.1|UniProtKB=W5MBC3 W5MBC3 PTHR10110:SF191 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 8 metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 import across plasma membrane#GO:0098739;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000000906.1|UniProtKB=W5LXZ7 W5LXZ7 PTHR15088:SF1 NUCLEAR FACTOR RIP140 NUCLEAR RECEPTOR-INTERACTING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009346.1|UniProtKB=W5MSP3 W5MSP3 PTHR11890:SF22 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN-LIKE 1 regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of transport#GO:0051051;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017838.1|UniProtKB=W5NMT2 W5NMT2 PTHR45617:SF186 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000664.1|UniProtKB=W5LX77 W5LX77 PTHR35673:SF1 UPF0500 PROTEIN C1ORF216 UPF0500 PROTEIN C1ORF216 LEPOC|Ensembl=ENSLOCG00000018055.1|UniProtKB=W5NNE7 W5NNE7 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000003241.1|UniProtKB=W5M621 W5M621 PTHR11066:SF34 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 8 hydrolase activity#GO:0016787;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;nucleobase-containing compound metabolic process#GO:0006139;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 hydrolase#PC00121;esterase#PC00097;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008962.1|UniProtKB=W5MRA9 W5MRA9 PTHR15075:SF7 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000016412.1|UniProtKB=W5NI10 W5NI10 PTHR31206:SF9 LP10445P PROTEIN FAM177B LEPOC|Ensembl=ENSLOCG00000006900.1|UniProtKB=W5MIY3 W5MIY3 PTHR45938:SF6 ACP24A4-RELATED WAP, KAZAL, IMMUNOGLOBULIN, KUNITZ AND NTR DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;protein binding#GO:0005515;growth factor binding#GO:0019838;signaling receptor regulator activity#GO:0030545;transforming growth factor beta binding#GO:0050431;molecular function regulator activity#GO:0098772;cytokine binding#GO:0019955 signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to transforming growth factor beta#GO:0071559;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013414.1|UniProtKB=W5N7D0 W5N7D0 PTHR28511:SF1 ENDONUCLEASE V ENDONUCLEASE V binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;single-stranded RNA binding#GO:0003727;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000000991.1|UniProtKB=W5LYB2 W5LYB2 PTHR43903:SF2 NEUROLIGIN NEUROLIGIN-1 plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic specialization#GO:0099572;organelle#GO:0043226;plasma membrane region#GO:0098590;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011231.1|UniProtKB=W5MZJ8 W5MZJ8 PTHR45854:SF2 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;positive regulation of cellular component organization#GO:0051130;organelle assembly#GO:0070925;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944 Integrin signalling pathway#P00034>ASAP1#P00909 LEPOC|Ensembl=ENSLOCG00000003304.1|UniProtKB=W5M6A4 W5M6A4 PTHR21452:SF4 EXPORTIN-6 EXPORTIN-6 protein export from nucleus#GO:0006611;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913 LEPOC|Ensembl=ENSLOCG00000016473.1|UniProtKB=W5NI92 W5NI92 PTHR24031:SF307 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX1 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;cytosol#GO:0005829 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000010768.1|UniProtKB=W5MXT7 W5MXT7 PTHR16442:SF1 RING FINGER PROTEIN 17 RING FINGER PROTEIN 17 LEPOC|Ensembl=ENSLOCG00000003133.1|UniProtKB=W5M5N7 W5M5N7 PTHR24300:SF48 CYTOCHROME P450 508A4-RELATED VITAMIN D 25-HYDROXYLASE tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;binding#GO:0005488;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;steroid metabolic process#GO:0008202;response to stimulus#GO:0050896;response to chemical#GO:0042221;lipid metabolic process#GO:0006629;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;vitamin D metabolic process#GO:0042359 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010752.1|UniProtKB=W5MXR3 W5MXR3 PTHR21555:SF0 SPECIFICALLY ANDROGEN-REGULATED GENE PROTEIN SPECIFICALLY ANDROGEN-REGULATED GENE PROTEIN hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to steroid hormone#GO:0048545;cellular response to chemical stimulus#GO:0070887;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;intracellular receptor signaling pathway#GO:0030522;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;steroid hormone receptor signaling pathway#GO:0043401;cellular response to steroid hormone stimulus#GO:0071383;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;nuclear receptor-mediated signaling pathway#GO:0141193;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000012883.1|UniProtKB=W5N5G0 W5N5G0 PTHR45745:SF3 PHOSPHOMANNOMUTASE 45A PHOSPHOPENTOMUTASE isomerase activity#GO:0016853;intramolecular phosphotransferase activity#GO:0016868;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 purine-containing compound biosynthetic process#GO:0072522;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule biosynthetic process#GO:0044283;purine nucleoside metabolic process#GO:0042278;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 metabolite interconversion enzyme#PC00262;isomerase#PC00135;mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000006105.1|UniProtKB=W5MG70 W5MG70 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008237.1|UniProtKB=W5MNP2 W5MNP2 PTHR43696:SF9 COILED-COIL DOMAIN-CONTAINING PROTEIN 157 COILED-COIL DOMAIN-CONTAINING PROTEIN 157 LEPOC|Ensembl=ENSLOCG00000006608.1|UniProtKB=W5MHX6 W5MHX6 TSFM PTHR11741:SF0 ELONGATION FACTOR TS ELONGATION FACTOR TS, MITOCHONDRIAL translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000005326.1|UniProtKB=W5MDF3 W5MDF3 PTHR31443:SF1 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 263 LEPOC|Ensembl=ENSLOCG00000013434.1|UniProtKB=W5N7F3 W5N7F3 PTHR13211:SF1 TELOMERASE CAJAL BODY PROTEIN 1 TELOMERASE CAJAL BODY PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016840.1|UniProtKB=W5NJK4 W5NJK4 PTHR11346:SF22 GALECTIN GALECTIN-8 binding#GO:0005488;carbohydrate binding#GO:0030246 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000016212.1|UniProtKB=W5NH81 W5NH81 PTHR13029:SF17 FAMILY NOT NAMED MYELIN REGULATORY FACTOR-LIKE PROTEIN transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;protein maturation#GO:0051604;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;regulation of biological process#GO:0050789;proteolysis#GO:0006508;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;nucleus#GO:0005634;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000009534.1|UniProtKB=W5MTF5 W5MTF5 PTHR10543:SF57 BETA-CAROTENE DIOXYGENASE RETINOID ISOMEROHYDROLASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;cis-trans isomerase activity#GO:0016859;dioxygenase activity#GO:0051213;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;isomerase activity#GO:0016853;oxidoreductase activity#GO:0016491;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;isoprenoid biosynthetic process#GO:0008299;olefinic compound metabolic process#GO:0120254;carotenoid biosynthetic process#GO:0016117;catabolic process#GO:0009056;primary metabolic process#GO:0044238;carotenoid metabolic process#GO:0016116;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;pigment biosynthetic process#GO:0046148;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;terpenoid biosynthetic process#GO:0016114;lipid biosynthetic process#GO:0008610;lipid catabolic process#GO:0016042;tetraterpenoid biosynthetic process#GO:0016109;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;xanthophyll biosynthetic process#GO:0016123;pigment metabolic process#GO:0042440 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000011889.1|UniProtKB=W5N1W2 W5N1W2 PTHR23322:SF111 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 2 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001958.1|UniProtKB=W5M1K7 W5M1K7 PTHR47980:SF9 LD44762P RAS-RELATED PROTEIN RAB-3A binding#GO:0005488;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 anterograde trans-synaptic signaling#GO:0098916;reproductive process#GO:0022414;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;anatomical structure development#GO:0048856;system development#GO:0048731;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;calcium-ion regulated exocytosis#GO:0017156;developmental process#GO:0032502;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;synaptic vesicle cycle#GO:0099504;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;export from cell#GO:0140352;signaling#GO:0023052;fertilization#GO:0009566;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;acrosome reaction#GO:0007340;regulation of biological process#GO:0050789;cellular localization#GO:0051641;secretion by cell#GO:0032940;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;single fertilization#GO:0007338;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;vesicle-mediated transport in synapse#GO:0099003;cell projection morphogenesis#GO:0048858;exocytosis#GO:0006887;regulated exocytosis#GO:0045055;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;acrosomal vesicle exocytosis#GO:0060478 organelle membrane#GO:0031090;plasma membrane#GO:0005886;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;intracellular organelle#GO:0043229;endosome#GO:0005768;exocytic vesicle#GO:0070382;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular vesicle#GO:0097708 Synaptic vesicle trafficking#P05734>Rab3A#P05780 LEPOC|Ensembl=ENSLOCG00000001143.1|UniProtKB=W5LZ11 W5LZ11 PTHR10075:SF44 BASIGIN RELATED NEURONAL CELL ADHESION MOLECULE cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001530.1|UniProtKB=W5M063 W5M063 PTHR12424:SF4 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 3 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000007701.1|UniProtKB=W5MLU1 W5MLU1 PTHR40141:SF2 3',5'-CYCLIC-AMP PHOSPHODIESTERASE-RELATED 3',5'-CYCLIC-AMP PHOSPHODIESTERASE LEPOC|Ensembl=ENSLOCG00000006647.1|UniProtKB=W5MI21 W5MI21 PTHR10782:SF12 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS2 catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular function inhibitor activity#GO:0140678;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789 protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;post-translational protein modification#GO:0043687;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of signaling#GO:0023057;protein modification by small protein conjugation or removal#GO:0070647;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;metabolic process#GO:0008152;protein sumoylation#GO:0016925 organelle lumen#GO:0043233;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958;JAK/STAT signaling pathway#P00038>PIAS#P01031 LEPOC|Ensembl=ENSLOCG00000006198.1|UniProtKB=W5MGH8 W5MGH8 PTHR23073:SF7 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6A ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000009537.1|UniProtKB=W5MTF7 W5MTF7 PTHR15535:SF26 TRANSMEMBRANE PROTEIN 2-RELATED CELL SURFACE HYALURONIDASE CEMIP2 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;glycosaminoglycan catabolic process#GO:0006027;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000013945.1|UniProtKB=W5N988 W5N988 PTHR10865:SF5 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;histone deacetylase binding#GO:0042826;transcription coactivator activity#GO:0003713;binding#GO:0005488;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;protein binding#GO:0005515 regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;response to ionizing radiation#GO:0010212;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;response to stress#GO:0006950;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;response to radiation#GO:0009314;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;DNA damage response#GO:0006974 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013533.1|UniProtKB=W5N7S9 W5N7S9 PTHR11909:SF451 CASEIN KINASE-RELATED TAU-TUBULIN KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cell communication#GO:0007154;organelle assembly#GO:0070925;signaling#GO:0023052;response to stimulus#GO:0050896;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;cilium assembly#GO:0060271 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;ciliary transition zone#GO:0035869;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000001866.1|UniProtKB=W5M1A1 W5M1A1 PTHR28052:SF1 UPF0545 PROTEIN C22ORF39 SYNAPTIC PLASTICITY REGULATOR PANTS LEPOC|Ensembl=ENSLOCG00000010299.1|UniProtKB=W5MW62 W5MW62 PTHR10909:SF390 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 3 organic acid binding#GO:0043177;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;lipid binding#GO:0008289;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363 metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017248.1|UniProtKB=W5NL25 W5NL25 PTHR11742:SF31 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IA hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005750.1|UniProtKB=W5MEY5 W5MEY5 PTHR24390:SF159 ZINC FINGER PROTEIN GROWTH FACTOR INDEPENDENT 1 TRANSCRIPTIONAL REPRESSOR transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011755.1|UniProtKB=W5N1E2 W5N1E2 PTHR10903:SF112 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000010457.1|UniProtKB=W5MWQ8 W5MWQ8 PTHR14649:SF1 ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C LEPOC|Ensembl=ENSLOCG00000018245.1|UniProtKB=W5NNY7 W5NNY7 PTHR19268:SF8 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 27-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015851.1|UniProtKB=W5NFV9 W5NFV9 PTHR11562:SF30 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A3-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;response to chemical#GO:0042221;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810;response to metal ion#GO:0010038;metal ion transport#GO:0030001;response to stimulus#GO:0050896;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008766.1|UniProtKB=W5MQL4 W5MQL4 PTHR46062:SF2 STEROL REGULATORY ELEMENT-BINDING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000004012.1|UniProtKB=W5M8T3 W5M8T3 PTHR23037:SF42 CYTOKINE RECEPTOR INTERLEUKIN-4 RECEPTOR SUBUNIT ALPHA ISOFORM 2 PRECURSOR cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;growth factor binding#GO:0019838;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signal transduction#GO:0007165;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005923.1|UniProtKB=W5MFJ4 W5MFJ4 PTHR13468:SF24 DEK PROTEIN PROTEIN DEK binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of DNA-templated transcription#GO:0006355;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141 membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000458.1|UniProtKB=W5LWJ9 W5LWJ9 PTHR44147:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 1 alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017016.1|UniProtKB=W5NK72 W5NK72 PTHR11208:SF34 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 2 mRNA binding#GO:0003729;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000002568.1|UniProtKB=W5M3Q7 W5M3Q7 PTHR11829:SF204 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000004255.1|UniProtKB=W5M9N3 W5M9N3 PTHR24251:SF59 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000004138.1|UniProtKB=W5M985 W5M985 PTHR24249:SF387 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013477.1|UniProtKB=W5N7L3 W5N7L3 PTHR12358:SF47 SPHINGOSINE KINASE SPHINGOSINE KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of localization#GO:0032879;regulation of transport#GO:0051049;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;regulation of apoptotic process#GO:0042981;regulation of endocytosis#GO:0030100;sphingolipid biosynthetic process#GO:0030148;negative regulation of cellular process#GO:0048523;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;biological regulation#GO:0065007;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;negative regulation of apoptotic process#GO:0043066;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;alcohol biosynthetic process#GO:0046165;sphingoid biosynthetic process#GO:0046520;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;small molecule metabolic process#GO:0044281;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 VEGF signaling pathway#P00056>SPK#P01404;Angiogenesis#P00005>SPK#P00229 LEPOC|Ensembl=ENSLOCG00000003209.1|UniProtKB=W5M5Z0 W5M5Z0 PTHR18966:SF174 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 3 extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;molecular transducer activity#GO:0060089;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943 cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;sodium channel complex#GO:0034706;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA3#P01002;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>KA#P01026 LEPOC|Ensembl=ENSLOCG00000016985.1|UniProtKB=W5NK37 W5NK37 PTHR24064:SF454 SOLUTE CARRIER FAMILY 22 MEMBER SI:DKEY-119M7.4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000016892.1|UniProtKB=W5NJS2 W5NJS2 PTHR13738:SF38 TROPONIN I TROPONIN I, SKELETAL, SLOW C ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 circulatory system process#GO:0003013;nervous system process#GO:0050877;neuromuscular process#GO:0050905;muscle contraction#GO:0006936;cardiac muscle contraction#GO:0060048;heart contraction#GO:0060047;system process#GO:0003008;heart process#GO:0003015;muscle system process#GO:0003012;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941 contractile muscle fiber#GO:0043292;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;sarcomere#GO:0030017;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000012976.1|UniProtKB=W5N5S6 W5N5S6 PTHR24347:SF379 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE FAMILY MEMBER 4 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000010297.1|UniProtKB=W5MW53 W5MW53 PTHR24211:SF40 LIM DOMAIN-CONTAINING PROTEIN PRICKLE HOMOLOG 2B cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018323.1|UniProtKB=W5NP65 W5NP65 PTHR38324:SF2 TRANSMEMBRANE PROTEIN 158 TRANSMEMBRANE PROTEIN 158 LEPOC|Ensembl=ENSLOCG00000009084.1|UniProtKB=W5MRT4 W5MRT4 PTHR11412:SF81 MACROGLOBULIN / COMPLEMENT COMPLEMENT C3 cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;humoral immune response#GO:0006959;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778;defense response to other organism#GO:0098542;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;positive regulation of biological process#GO:0048518;complement activation#GO:0006956;defense response to symbiont#GO:0140546;immune response#GO:0006955;activation of immune response#GO:0002253 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000015728.1|UniProtKB=W5NFF1 W5NFF1 PTHR24064:SF461 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000016170.1|UniProtKB=W5NH17 W5NH17 PTHR47958:SF195 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000015011.1|UniProtKB=W5NCX0 W5NCX0 PTHR19860:SF18 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 41-RELATED transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000002127.1|UniProtKB=W5M267 W5M267 PTHR22750:SF59 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007050.1|UniProtKB=W5MJI8 W5MJI8 PTHR22807:SF30 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;rRNA base methylation#GO:0070475;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000014638.1|UniProtKB=W5NBK9 W5NBK9 PTHR10454:SF155 CASPASE CASPASE-15 endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;positive regulation of neuron apoptotic process#GO:0043525;epidermis development#GO:0008544;developmental process#GO:0032502;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;regulation of neuron apoptotic process#GO:0043523;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;tissue development#GO:0009888;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000304.1|UniProtKB=W5LW24 W5LW24 PTHR47614:SF2 GLYCOPHORIN-C GLYCOPHORIN-C membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical cytoskeleton#GO:0030863;membrane#GO:0016020;cell cortex#GO:0005938;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000003352.1|UniProtKB=W5M6F7 W5M6F7 PTHR12241:SF39 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL9-RELATED catalytic activity, acting on a protein#GO:0140096;tubulin binding#GO:0015631;ligase activity#GO:0016874;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017393.1|UniProtKB=W5NLI9 W5NLI9 PTHR11232:SF36 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN FAM43A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016779.1|UniProtKB=W5NJD2 W5NJD2 PTHR23112:SF36 G PROTEIN-COUPLED RECEPTOR 157-RELATED SI:DKEY-30C15.2 PROTEIN transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009795.1|UniProtKB=W5MUB8 W5MUB8 PTHR48015:SF23 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE 3 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;hippo signaling#GO:0035329;negative regulation of signal transduction#GO:0009968;regulation of canonical Wnt signaling pathway#GO:0060828;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016891.1|UniProtKB=W5NJS0 W5NJS0 PTHR24365:SF539 TOLL-LIKE RECEPTOR TIR DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;cell communication#GO:0007154;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune system process#GO:0002376;toll-like receptor signaling pathway#GO:0002224;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;regulation of response to external stimulus#GO:0032101 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007523.1|UniProtKB=W5ML67 W5ML67 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002067.1|UniProtKB=W5M1Y8 W5M1Y8 PTHR32061:SF4 NMDA RECEPTOR SYNAPTONUCLEAR SIGNALING AND NEURONAL MIGRATION FACTOR NMDA RECEPTOR SYNAPTONUCLEAR SIGNALING AND NEURONAL MIGRATION FACTOR biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell migration#GO:0030335;positive regulation of cell motility#GO:2000147;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;regulation of cell migration#GO:0030334;regulation of neuron migration#GO:2001222 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000009647.1|UniProtKB=W5MTT2 W5MTT2 PTHR24384:SF192 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 47 ISOFORM X1 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012361.1|UniProtKB=W5N3K8 W5N3K8 PTHR10811:SF1 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE RADICAL FRINGE hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of Notch signaling pathway#GO:0008593;regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 glycosyltransferase#PC00111;transferase#PC00220 Notch signaling pathway#P00045>Fringe#P01107 LEPOC|Ensembl=ENSLOCG00000009095.1|UniProtKB=W5MRT0 W5MRT0 PTHR13832:SF883 PROTEIN PHOSPHATASE 2C INTEGRIN-LINKED KINASE-ASSOCIATED SERINE_THREONINE PHOSPHATASE 2C phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000009856.1|UniProtKB=W5MUJ1 W5MUJ1 PTHR12195:SF5 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN 2 axon development#GO:0061564;axon guidance#GO:0007411;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;programmed cell death#GO:0012501;cell death#GO:0008219;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of protein metabolic process#GO:0051246;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409 neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 LEPOC|Ensembl=ENSLOCG00000007550.1|UniProtKB=W5MLA4 W5MLA4 PTHR43842:SF2 PROPIONYL-COA CARBOXYLASE BETA CHAIN PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ligase#PC00142;metabolite interconversion enzyme#PC00262 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163;Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 LEPOC|Ensembl=ENSLOCG00000007049.1|UniProtKB=W5MJH2 W5MJH2 PTHR20952:SF0 ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 1 endoplasmic reticulum tubular network organization#GO:0071786;cellular component assembly#GO:0022607;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum tubular network#GO:0071782 LEPOC|Ensembl=ENSLOCG00000012715.1|UniProtKB=W5N4U6 W5N4U6 PTHR10957:SF2 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000016277.1|UniProtKB=W5NHG9 W5NHG9 PTHR24161:SF18 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE ZDHHC17 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096 system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002720.1|UniProtKB=W5M4B3 W5M4B3 PTHR44157:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012974.1|UniProtKB=W5N5U3 W5N5U3 PTHR22605:SF21 RZ-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF213-BETA-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;blood vessel morphogenesis#GO:0048514;regulation of Wnt signaling pathway#GO:0030111;circulatory system development#GO:0072359;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;sprouting angiogenesis#GO:0002040;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;negative regulation of cell communication#GO:0010648;angiogenesis#GO:0001525;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;tube development#GO:0035295;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000005571.1|UniProtKB=W5MEB5 W5MEB5 PTHR22750:SF21 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012008.1|UniProtKB=W5N2B1 W5N2B1 PTHR21635:SF0 LEUCINE ZIPPER TRANSCRIPTION FACTOR LIKE LEUCINE ZIPPER TRANSCRIPTION FACTOR-LIKE PROTEIN 1 cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;sperm motility#GO:0097722;cilium-dependent cell motility#GO:0060285;regulation of protein localization#GO:0032880;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;biological regulation#GO:0065007;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;regulation of localization#GO:0032879;microtubule-based process#GO:0007017;flagellated sperm motility#GO:0030317 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000001295.1|UniProtKB=W5LZD9 W5LZD9 PTHR12181:SF62 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN3 catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;hydrolase activity#GO:0016787 metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;lipid catabolic process#GO:0016042;response to hormone#GO:0009725;fatty acid catabolic process#GO:0009062;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;small molecule catabolic process#GO:0044282;cellular response to hormone stimulus#GO:0032870;glycerolipid metabolic process#GO:0046486;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;response to endogenous stimulus#GO:0009719;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;cellular response to insulin stimulus#GO:0032869;fatty acid metabolic process#GO:0006631;acylglycerol metabolic process#GO:0006639;response to peptide hormone#GO:0043434;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;positive regulation of DNA-templated transcription#GO:0045893;monocarboxylic acid catabolic process#GO:0072329;cellular response to nitrogen compound#GO:1901699;triglyceride biosynthetic process#GO:0019432;regulation of nucleobase-containing compound metabolic process#GO:0019219;glycerolipid biosynthetic process#GO:0045017;positive regulation of cellular process#GO:0048522;carboxylic acid catabolic process#GO:0046395;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular response to peptide hormone stimulus#GO:0071375;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000015952.1|UniProtKB=W5NG89 W5NG89 PTHR13239:SF6 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 STRIATIN-INTERACTING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;cellular process#GO:0009987;organelle organization#GO:0006996;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000003716.1|UniProtKB=W5M7R5 W5M7R5 PTHR11477:SF50 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 3 ISOFORM X1 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001694.1|UniProtKB=W5M0P7 W5M0P7 PTHR11188:SF182 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014528.1|UniProtKB=W5NB86 W5NB86 PTHR18966:SF151 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 3 ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;molecular transducer activity#GO:0060089;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cell projection#GO:0042995;neuron spine#GO:0044309;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>Glu3#P01016 LEPOC|Ensembl=ENSLOCG00000004656.1|UniProtKB=W5MB47 W5MB47 PTHR24351:SF197 RIBOSOMAL PROTEIN S6 KINASE SERINE_THREONINE-PROTEIN KINASE SGK1 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008416.1|UniProtKB=W5MPC0 W5MPC0 PTHR16223:SF268 TRANSCRIPTION FACTOR BHLH83-RELATED BHLH DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013981.1|UniProtKB=W5N9C4 W5N9C4 PTHR10701:SF5 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNIT RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000003108.1|UniProtKB=W5M5L0 W5M5L0 PTHR24031:SF301 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX18 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000009253.1|UniProtKB=W5MSD6 W5MSD6 PTHR45622:SF11 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC6-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014358.1|UniProtKB=W5NAM2 W5NAM2 PTHR23423:SF21 ORGANIC SOLUTE TRANSPORTER-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT ALPHA transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005137.1|UniProtKB=W5MCS6 W5MCS6 PTHR46511:SF1 MORN REPEAT-CONTAINING PROTEIN 3 MORN REPEAT-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000011862.1|UniProtKB=W5N1V6 W5N1V6 PTHR45857:SF2 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000000598.1|UniProtKB=W5LX00 W5LX00 PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;ion binding#GO:0043167;lipase activity#GO:0016298;small molecule binding#GO:0036094;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475 organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 LEPOC|Ensembl=ENSLOCG00000011601.1|UniProtKB=W5N0U6 W5N0U6 PTHR45956:SF7 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN PROTEIN RUFY3 ISOFORM X1 regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of axonogenesis#GO:0050770;regulation of cell projection organization#GO:0031344;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of neuron projection development#GO:0010975 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000016397.1|UniProtKB=W5NHZ6 W5NHZ6 PTHR11036:SF23 SEMAPHORIN SEMAPHORIN-3A binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 mesenchyme development#GO:0060485;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;stem cell development#GO:0048864;chemotaxis#GO:0006935;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;taxis#GO:0042330;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;neural crest cell migration#GO:0001755;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell development#GO:0048468;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;developmental process#GO:0032502;cell migration#GO:0016477;neural crest cell development#GO:0014032;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;stem cell differentiation#GO:0048863;axon development#GO:0061564;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;locomotion#GO:0040011;animal organ development#GO:0048513;cell projection morphogenesis#GO:0048858;mesenchymal cell differentiation#GO:0048762;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neural crest cell differentiation#GO:0014033;response to chemical#GO:0042221;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;signaling#GO:0023052;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;positive regulation of cell motility#GO:2000147 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;axon#GO:0030424;extracellular region#GO:0005576;cell junction#GO:0030054 membrane-bound signaling molecule#PC00152 Axon guidance mediated by semaphorins#P00007>Sema3A#P00337 LEPOC|Ensembl=ENSLOCG00000011093.1|UniProtKB=W5MZ40 W5MZ40 PTHR12181:SF11 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN2 transcription regulator activity#GO:0140110;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;transcription coactivator activity#GO:0003713 cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;primary metabolic process#GO:0044238;cellular response to peptide hormone stimulus#GO:0071375;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;carboxylic acid catabolic process#GO:0046395;positive regulation of cellular process#GO:0048522;glycerolipid biosynthetic process#GO:0045017;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;response to peptide hormone#GO:0043434;regulation of nucleobase-containing compound metabolic process#GO:0019219;triglyceride biosynthetic process#GO:0019432;monocarboxylic acid catabolic process#GO:0072329;cellular response to nitrogen compound#GO:1901699;lipid biosynthetic process#GO:0008610;positive regulation of DNA-templated transcription#GO:0045893;cellular response to insulin stimulus#GO:0032869;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;acylglycerol metabolic process#GO:0006639;regulation of gene expression#GO:0010468;neutral lipid metabolic process#GO:0006638;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;cellular response to hormone stimulus#GO:0032870;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;fatty acid catabolic process#GO:0009062;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to oxygen-containing compound#GO:1901701;lipid catabolic process#GO:0016042;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to hormone#GO:0009725;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152 endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829;nucleus#GO:0005634;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004793.1|UniProtKB=W5MBI8 W5MBI8 PTHR11471:SF24 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004226.1|UniProtKB=W5M9J5 W5M9J5 PTHR24103:SF700 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM7 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000372.1|UniProtKB=W5LWA0 W5LWA0 PTHR12207:SF23 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2A membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011452.1|UniProtKB=W5N0B2 W5N0B2 PTHR24393:SF18 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 652 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010142.1|UniProtKB=W5MVK5 W5MVK5 PTHR21223:SF4 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 1 cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;ciliary transition zone#GO:0035869;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000001140.1|UniProtKB=W5LYT2 W5LYT2 PTHR18934:SF108 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE HOMOLOG DQX1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000004929.1|UniProtKB=W5MC28 W5MC28 PTHR10881:SF46 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 2 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009841.1|UniProtKB=W5MUG8 W5MUG8 PTHR24206:SF95 OS06G0237300 PROTEIN CYTOSKELETON-ASSOCIATED LIM DOMAIN PROTEIN-RELATED actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;actin filament bundle assembly#GO:0051017;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000012407.1|UniProtKB=W5N3S6 W5N3S6 PTHR11635:SF129 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;kinase binding#GO:0019900;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase inhibitor activity#GO:0019210;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;protein kinase A binding#GO:0051018;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Endothelin signaling pathway#P00019>PKA#P00570;GABA-B receptor II signaling#P05731>PKA#P05752;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Hedgehog signaling pathway#P00025>PKA#P00682;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 LEPOC|Ensembl=ENSLOCG00000004803.1|UniProtKB=W5MBK2 W5MBK2 PTHR24334:SF3 HOMEOBOX PROTEIN GBX HOMEOBOX PROTEIN GBX-2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013790.1|UniProtKB=W5N8P8 W5N8P8 PTHR44554:SF1 LRP2-BINDING PROTEIN LRP2-BINDING PROTEIN LEPOC|Ensembl=ENSLOCG00000000831.1|UniProtKB=W5LXR8 W5LXR8 PTHR10751:SF1 GUANYLATE BINDING PROTEIN RING FINGER PROTEIN 112 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005462.1|UniProtKB=W5MDZ1 W5MDZ1 PTHR22826:SF49 RHO GUANINE EXCHANGE FACTOR-RELATED KALIRIN guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;intracellular signal transduction#GO:0035556;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008 postsynapse#GO:0098794;membrane#GO:0016020;cytoplasm#GO:0005737;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic density#GO:0014069;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 Huntington disease#P00029>Duo#P00773 LEPOC|Ensembl=ENSLOCG00000005065.1|UniProtKB=W5MCI7 W5MCI7 PTHR34438:SF1 SI:DKEY-97L20.6 CHROMOSOME 2 OPEN READING FRAME 81 LEPOC|Ensembl=ENSLOCG00000005976.1|UniProtKB=W5MFR6 W5MFR6 PTHR15672:SF13 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN R3H DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000004470.1|UniProtKB=W5MAD5 W5MAD5 PTHR24171:SF8 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000001510.1|UniProtKB=W5M019 W5M019 PTHR10872:SF4 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 2 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159 B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of immune response#GO:0050776;immune system process#GO:0002376;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001388.1|UniProtKB=W5LZM3 W5LZM3 PTHR11958:SF93 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 2 sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;solute:monoatomic cation symporter activity#GO:0015294;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;sodium ion transmembrane transporter activity#GO:0015081;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175 L-alpha-amino acid transmembrane transport#GO:1902475;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;L-glutamate import#GO:0051938;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;aspartate transmembrane transport#GO:0015810;cellular process#GO:0009987;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 LEPOC|Ensembl=ENSLOCG00000008193.1|UniProtKB=W5MNI5 W5MNI5 PTHR22698:SF1 PDZ DOMAIN-CONTAINING PROTEIN 9 PDZ DOMAIN-CONTAINING PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000008254.1|UniProtKB=W5MNR3 W5MNR3 PTHR10366:SF241 NAD DEPENDENT EPIMERASE/DEHYDRATASE SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E MEMBER 2-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 lyase#PC00144;dehydratase#PC00091;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013449.1|UniProtKB=W5N7H4 W5N7H4 PTHR10210:SF28 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000001618.1|UniProtKB=W5M0F8 W5M0F8 PTHR32123:SF12 BICD FAMILY-LIKE CARGO ADAPTER BICD FAMILY-LIKE CARGO ADAPTER 1 vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;vesicle cytoskeletal trafficking#GO:0099518;microtubule-based process#GO:0007017;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012717.1|UniProtKB=W5N4U5 W5N4U5 PTHR10378:SF7 LIM DOMAIN-BINDING PROTEIN LIM DOMAIN-BINDING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>CLIM2#P06736 LEPOC|Ensembl=ENSLOCG00000005255.1|UniProtKB=W5MD84 W5MD84 PTHR11447:SF21 CELLULAR TUMOR ANTIGEN P53 TUMOR PROTEIN P73 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell death#GO:0008219;cellular response to stimulus#GO:0051716;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;regulation of gene expression#GO:0010468;apoptotic signaling pathway#GO:0097190;regulation of biosynthetic process#GO:0009889;DNA damage response#GO:0006974;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;intrinsic apoptotic signaling pathway#GO:0097193;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;regulation of apoptotic process#GO:0042981;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 P53-like transcription factor#PC00253;gene-specific transcriptional regulator#PC00264 P53 pathway feedback loops 1#P04392>p73#G04686;p53 pathway by glucose deprivation#P04397>p53#P04640;p53 pathway feedback loops 2#P04398>p53#P04668;P53 pathway feedback loops 1#P04392>p53#P04539;Huntington disease#P00029>p53#P00797;p53 pathway#P00059>p53#P01485;p53 pathway#P00059>p53#G04702 LEPOC|Ensembl=ENSLOCG00000014635.1|UniProtKB=W5NBK5 W5NBK5 PTHR15002:SF0 RIBOSOMAL BIOGENESIS PROTEIN LAS1L RIBOSOMAL BIOGENESIS PROTEIN LAS1L catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000013218.1|UniProtKB=W5N6M4 W5N6M4 PTHR23048:SF50 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 4 structural molecule activity#GO:0005198;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000018242.1|UniProtKB=W5NNY4 W5NNY4 PTHR24235:SF11 NEUROPEPTIDE Y RECEPTOR PROLACTIN-RELEASING PEPTIDE RECEPTOR molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;feeding behavior#GO:0007631;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006543.1|UniProtKB=W5MHP6 W5MHP6 PTHR15698:SF8 PROTEIN CBG15099 PHYTANOYL-COA HYDROXYLASE-INTERACTING PROTEIN-LIKE intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016204.1|UniProtKB=W5NH72 W5NH72 PTHR14430:SF2 RABIN3-RELATED RAB-3A-INTERACTING PROTEIN enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000013946.1|UniProtKB=W5N979 W5N979 PTHR16244:SF2 CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 6 CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 6 intracellular organelle lumen#GO:0070013;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;membrane raft#GO:0045121;organelle lumen#GO:0043233;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;membrane microdomain#GO:0098857;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000018369.1|UniProtKB=W5NPB1 W5NPB1 PTHR26451:SF998 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005758.1|UniProtKB=W5MEZ2 W5MEZ2 PTHR13168:SF0 ASSOCIATE OF C-MYC AMY-1 C-MYC-BINDING PROTEIN transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 PDGF signaling pathway#P00047>c-Myc#P01172 LEPOC|Ensembl=ENSLOCG00000012096.1|UniProtKB=W5N2M9 W5N2M9 PTHR11109:SF11 GTP CYCLOHYDROLASE I GTP CYCLOHYDROLASE 1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814 small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;biosynthetic process#GO:0009058;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Tetrahydrofolate biosynthesis#P02742>GTP cyclohydrolase#P02951 LEPOC|Ensembl=ENSLOCG00000015800.1|UniProtKB=W5NFP1 W5NFP1 PTHR14592:SF10 UNCHARACTERIZED FAM3 PROTEIN FAM3C molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006865.1|UniProtKB=W5MIU2 W5MIU2 PTHR14964:SF2 NUCLEAR RECEPTOR BINDING FACTOR 2 NUCLEAR RECEPTOR-BINDING FACTOR 2 catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;metabolic process#GO:0008152;cellular process#GO:0009987;autophagy#GO:0006914 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000004454.1|UniProtKB=W5MAB4 W5MAB4 PTHR14009:SF13 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN LETM1 DOMAIN-CONTAINING PROTEIN 1 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003722.1|UniProtKB=W5M7T0 W5M7T0 PTHR11073:SF61 CALRETICULIN AND CALNEXIN CALRETICULIN calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;response to chemical#GO:0042221;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein folding#GO:0006457;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005106.1|UniProtKB=W5MCN8 W5MCN8 PTHR12474:SF2 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-2 catalytic activity#GO:0003824;amino acid binding#GO:0016597;oxidoreductase activity#GO:0016491;organic acid binding#GO:0043177;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;cation binding#GO:0043169 cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;cellular response to amino acid starvation#GO:0034198;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;response to acid chemical#GO:0001101;regulation of macroautophagy#GO:0016241;negative regulation of TORC1 signaling#GO:1904262;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;positive regulation of macroautophagy#GO:0016239;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000015345.1|UniProtKB=W5NE29 W5NE29 PTHR13773:SF4 PHOSPHATIDATE CYTIDYLYLTRANSFERASE PHOSPHATIDATE CYTIDYLYLTRANSFERASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular component assembly#GO:0022607;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid storage#GO:0019915;cellular component biogenesis#GO:0044085;organophosphate metabolic process#GO:0019637;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;organelle assembly#GO:0070925;lipid droplet organization#GO:0034389 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000006408.1|UniProtKB=W5MH82 W5MH82 PTHR32215:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011479.1|UniProtKB=W5N0F4 W5N0F4 PTHR24055:SF533 MITOGEN-ACTIVATED PROTEIN KINASE MAPK_MAK_MRK OVERLAPPING KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017123.1|UniProtKB=W5NKK5 W5NKK5 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004695.1|UniProtKB=W5MB74 W5MB74 PTHR22957:SF679 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN ECOTROPIC VIRAL INTEGRATION SITE 5 PROTEIN HOMOLOG enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 intracellular transport#GO:0046907;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000011939.1|UniProtKB=W5N224 W5N224 PTHR31684:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 LEPOC|Ensembl=ENSLOCG00000017222.1|UniProtKB=W5NKY9 W5NKY9 PTHR12877:SF14 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 10 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 organelle assembly#GO:0070925;actin filament-based process#GO:0030029;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;regulation of supramolecular fiber organization#GO:1902903;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;regulation of actin filament-based process#GO:0032970;spindle organization#GO:0007051;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;positive regulation of actin filament bundle assembly#GO:0032233;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;nuclear division#GO:0000280;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;regulation of biological process#GO:0050789;mitotic spindle organization#GO:0007052;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000013874.1|UniProtKB=W5N906 W5N906 PTHR28583:SF1 ACID AMIDASE ACID CERAMIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000004974.1|UniProtKB=W5MC87 W5MC87 PTHR17550:SF8 E3 UBIQUITIN-PROTEIN LIGASE TTC3 RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015443.1|UniProtKB=W5NEE9 W5NEE9 PTHR12751:SF5 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 2 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000006123.1|UniProtKB=W5MG92 W5MG92 PTHR12857:SF0 CXXC MOTIF CONTAINING ZINC BINDING PROTEIN CXXC MOTIF CONTAINING ZINC BINDING PROTEIN transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 LEPOC|Ensembl=ENSLOCG00000008895.1|UniProtKB=W5MR26 W5MR26 PTHR46657:SF1 CENTROSOMAL PROTEIN OF 128 KDA CENTROSOMAL PROTEIN 128 intracellular organelle#GO:0043229;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014977.1|UniProtKB=W5NCT8 W5NCT8 PTHR46184:SF3 UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN UNCONVENTIONAL MYOSIN-IXA cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of apical/basal cell polarity#GO:0035088;tissue morphogenesis#GO:0048729;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;anatomical structure development#GO:0048856;establishment of cell polarity#GO:0030010;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;developmental process#GO:0032502;morphogenesis of an epithelium#GO:0002009;cellular developmental process#GO:0048869;cellular process#GO:0009987;epithelium development#GO:0060429;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855 cytoskeleton#GO:0005856;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;neuron projection#GO:0043005;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;axonal growth cone#GO:0044295;growth cone#GO:0030426;axon#GO:0030424;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell projection#GO:0042995 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000008101.1|UniProtKB=W5MN85 W5MN85 PTHR22804:SF41 AGGRECAN/VERSICAN PROTEOGLYCAN BREVICAN CORE PROTEIN developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417 extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;extracellular region#GO:0005576;cell junction#GO:0030054 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000006801.1|UniProtKB=W5MIL8 W5MIL8 PTHR45630:SF20 CATION-TRANSPORTING ATPASE-RELATED ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657 transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;localization within membrane#GO:0051668;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;cellular process#GO:0009987;establishment of protein localization#GO:0045184;monoatomic ion homeostasis#GO:0050801;establishment of protein localization to membrane#GO:0090150 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000018300.1|UniProtKB=W5NP42 W5NP42 PTHR11984:SF12 CONNEXIN GAP JUNCTION ALPHA-3 PROTEIN passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cell communication#GO:0007154;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of biological process#GO:0050789 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000008821.1|UniProtKB=W5MQS1 W5MQS1 PTHR21013:SF10 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000018345.1|UniProtKB=W5NP87 W5NP87 PTHR36690:SF2 PROTEIN FAM237A PROTEIN FAM237A LEPOC|Ensembl=ENSLOCG00000009592.1|UniProtKB=W5MTK9 W5MTK9 PTHR10142:SF0 DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS nucleic acid binding#GO:0003676;binding#GO:0005488;damaged DNA binding#GO:0003684;DNA binding#GO:0003677 cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;response to radiation#GO:0009314;organelle organization#GO:0006996;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;nucleotide-excision repair#GO:0006289;response to UV#GO:0009411;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular response to abiotic stimulus#GO:0071214;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;response to abiotic stimulus#GO:0009628;cellular response to radiation#GO:0071478;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to environmental stimulus#GO:0104004;cellular response to stress#GO:0033554 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleotide-excision repair complex#GO:0000109;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000004485.1|UniProtKB=W5MAF2 W5MAF2 PTHR46252:SF2 BRORIN FAMILY MEMBER VON WILLEBRAND FACTOR C DOMAIN-CONTAINING PROTEIN 2-LIKE negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of BMP signaling pathway#GO:0030510;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789 extracellular region#GO:0005576;signaling receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000016708.1|UniProtKB=W5NJ31 W5NJ31 PTHR12879:SF2 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE DES1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide metabolic process#GO:0006672 hydroxylase#PC00122;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004369.1|UniProtKB=W5MA23 W5MA23 PTHR24198:SF175 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000006974.1|UniProtKB=W5MJ84 W5MJ84 PTHR10443:SF9 MICROSOMAL DIPEPTIDASE DIPEPTIDASE 2 peptidase activity#GO:0008233;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013634.1|UniProtKB=W5N848 W5N848 PTHR12025:SF3 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR C receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of leukocyte migration#GO:0002685;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;positive regulation of chemotaxis#GO:0050921;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;tube development#GO:0035295;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;response to hypoxia#GO:0001666;positive regulation of locomotion#GO:0040017;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;developmental process#GO:0032502;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;blood vessel morphogenesis#GO:0048514;response to endogenous stimulus#GO:0009719;vascular endothelial growth factor receptor signaling pathway#GO:0048010;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;cellular response to growth factor stimulus#GO:0071363;angiogenesis#GO:0001525;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;positive regulation of response to external stimulus#GO:0032103;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012440.1|UniProtKB=W5N3V2 W5N3V2 PTHR13286:SF6 SAP30 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30L transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014361.1|UniProtKB=W5NAN8 W5NAN8 PTHR11814:SF113 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 6 carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108 chloride transport#GO:0006821;transport#GO:0006810;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001037.1|UniProtKB=W5LYF2 W5LYF2 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000004780.1|UniProtKB=W5MBH4 W5MBH4 PTHR15135:SF3 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106 neuromuscular process#GO:0050905;nervous system process#GO:0050877;regulation of protein localization#GO:0032880;regulation of biological process#GO:0050789;muscle system process#GO:0003012;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;regulation of cellular process#GO:0050794;muscle contraction#GO:0006936;system process#GO:0003008;regulation of localization#GO:0032879;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of protein localization to membrane#GO:1905475;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 LEPOC|Ensembl=ENSLOCG00000005535.1|UniProtKB=W5ME77 W5ME77 PTHR47077:SF1 ION_TRANS DOMAIN-CONTAINING PROTEIN CATION CHANNEL SPERM-ASSOCIATED PROTEIN 4 transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832 sodium ion transport#GO:0006814;sperm motility#GO:0097722;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;monoatomic ion transport#GO:0006811;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;sperm capacitation#GO:0048240;microtubule-based process#GO:0007017;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;metal ion transport#GO:0030001;spermatid development#GO:0007286;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;monoatomic cation transport#GO:0006812;localization#GO:0051179;multicellular organismal reproductive process#GO:0048609;male gamete generation#GO:0048232;developmental maturation#GO:0021700;flagellated sperm motility#GO:0030317;transport#GO:0006810;developmental process#GO:0032502;spermatogenesis#GO:0007283;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;cell maturation#GO:0048469 transporter complex#GO:1990351;cation channel complex#GO:0034703;CatSper complex#GO:0036128;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;acrosomal vesicle#GO:0001669;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;voltage-gated calcium channel complex#GO:0005891;intracellular vesicle#GO:0097708;sperm principal piece#GO:0097228;calcium channel complex#GO:0034704;endomembrane system#GO:0012505;monoatomic ion channel complex#GO:0034702;sperm flagellum#GO:0036126;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;motile cilium#GO:0031514;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000004328.1|UniProtKB=W5M9Y4 W5M9Y4 PTHR46540:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 12 TETRATRICOPEPTIDE REPEAT PROTEIN 12 flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;axonemal dynein complex assembly#GO:0070286;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;sperm motility#GO:0097722;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000014993.1|UniProtKB=W5NCV2 W5NCV2 PTHR12963:SF6 THYROID RECEPTOR INTERACTING PROTEIN RELATED ACTIVATING SIGNAL COINTEGRATOR 1 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;translational elongation#GO:0006414;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rescue of stalled cytosolic ribosome#GO:0072344;modification-dependent protein catabolic process#GO:0019941;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;catabolic process#GO:0009056;cytoplasmic translation#GO:0002181;modification-dependent macromolecule catabolic process#GO:0043632;translation#GO:0006412;protein catabolic process#GO:0030163;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000001763.1|UniProtKB=W5M0Y8 W5M0Y8 PTHR24346:SF56 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE MARK2 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011546.1|UniProtKB=W5N0M6 W5N0M6 PTHR31025:SF32 SI:CH211-196P9.1-RELATED SUBFAMILY NOT NAMED LEPOC|Ensembl=ENSLOCG00000011473.1|UniProtKB=W5N0E3 W5N0E3 PTHR22957:SF225 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 9B enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000006909.1|UniProtKB=W5MJ00 W5MJ00 PTHR10169:SF36 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2-BETA catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 organelle organization#GO:0006996;cellular process#GO:0009987;resolution of meiotic recombination intermediates#GO:0000712;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;nuclear chromosome segregation#GO:0098813;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;organelle fission#GO:0048285 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 LEPOC|Ensembl=ENSLOCG00000001173.1|UniProtKB=W5LYW1 W5LYW1 PTHR11681:SF5 NEUROPHYSIN ISOTOCIN signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;neuropeptide hormone activity#GO:0005184;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 peptide hormone#PC00179;neuropeptide#PC00162 Opioid prodynorphin pathway#P05916>prepropressophysin#G06048;Vasopressin synthesis#P04395>Pro-Neurophysin#P04591;Opioid prodynorphin pathway#P05916>provasopressin#P05999;Vasopressin synthesis#P04395>Vasopressin#P04590;Opioid prodynorphin pathway#P05916>vasopressin#P06000;Opioid prodynorphin pathway#P05916>prepropressophysin#G06050;Vasopressin synthesis#P04395>Glycopeptide#P04593;Vasopressin synthesis#P04395>Signal Peptide#P04597;Vasopressin synthesis#P04395>Pro-Vasopressin#P04598;Vasopressin synthesis#P04395>Neurophysin#P04594;Vasopressin synthesis#P04395>Pro2-Vasopressin#P04595 LEPOC|Ensembl=ENSLOCG00000015260.1|UniProtKB=W5NDR9 W5NDR9 PTHR45476:SF3 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 transport#GO:0006810;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;localization#GO:0051179;establishment of localization#GO:0051234 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000013005.1|UniProtKB=W5N5W2 W5N5W2 PTHR14338:SF4 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1-LIKE 2 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295 regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of macromolecule metabolic process#GO:0010604;inflammatory response#GO:0006954;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of ERBB signaling pathway#GO:1901184;positive regulation of signal transduction#GO:0009967;positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001723.1|UniProtKB=W5M0T1 W5M0T1 PTHR13943:SF31 HRAS-LIKE SUPPRESSOR - RELATED RETINOIC ACID RECEPTOR RESPONDER 3-RELATED glycerophospholipase activity#GO:0004620;transferase activity#GO:0016740;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;A2-type glycerophospholipase activity#GO:0004623;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000017672.1|UniProtKB=W5NMB8 W5NMB8 PTHR32341:SF21 INTERFERON-INDUCIBLE GTPASE IRG-TYPE G DOMAIN-CONTAINING PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000009637.1|UniProtKB=W5MTS2 W5MTS2 PTHR45766:SF6 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER SNF2 RELATED CHROMATIN REMODELING ANNEALING HELICASE 1 single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;cellular process#GO:0009987;response to stress#GO:0006950;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000005764.1|UniProtKB=W5MF03 W5MF03 PTHR15427:SF26 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT A signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 positive regulation of biological process#GO:0048518;immune response#GO:0006955;complement activation#GO:0006956;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;adaptive immune response#GO:0002250;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;humoral immune response#GO:0006959;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005609.1|UniProtKB=W5MEG2 W5MEG2 PTHR11742:SF28 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IC hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010209.1|UniProtKB=W5MVT9 W5MVT9 PTHR10231:SF36 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-N-ACETYLGLUCOSAMINE TRANSPORTER carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;UDP-galactose transmembrane transporter activity#GO:0005459;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005182.1|UniProtKB=W5MCX8 W5MCX8 PTHR15077:SF9 FAS-ASSOCIATING DEATH DOMAIN-CONTAINING PROTEIN FADD FAS-ASSOCIATED DEATH DOMAIN PROTEIN Apoptosis signaling pathway#P00006>FADD#P00327;FAS signaling pathway#P00020>FADD#P00622 LEPOC|Ensembl=ENSLOCG00000010955.1|UniProtKB=W5MYH9 W5MYH9 PTHR11035:SF22 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 1 catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000001427.1|UniProtKB=W5LZY1 W5LZY1 PTHR23119:SF5 DISCS LARGE DISKS LARGE HOMOLOG 1 structural molecule activity#GO:0005198;binding#GO:0005488;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;structural constituent of synapse#GO:0098918 signaling#GO:0023052;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;receptor clustering#GO:0043113;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;nervous system development#GO:0007399;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;multicellular organism development#GO:0007275;protein localization to synapse#GO:0035418;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;establishment or maintenance of bipolar cell polarity#GO:0061245;localization within membrane#GO:0051668;establishment or maintenance of apical/basal cell polarity#GO:0035088;trans-synaptic signaling#GO:0099537;protein localization to cell junction#GO:1902414;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;developmental process#GO:0032502;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072 synaptic membrane#GO:0097060;cell junction#GO:0030054;neuromuscular junction#GO:0031594;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;neuron projection#GO:0043005;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;basal part of cell#GO:0045178;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002910.1|UniProtKB=W5M4V9 W5M4V9 PTHR13392:SF5 ATAXIN 1 ATAXIN-1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;head development#GO:0060322;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000000450.1|UniProtKB=W5LWI6 W5LWI6 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000002815.1|UniProtKB=W5M4K2 W5M4K2 PTHR10218:SF65 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(Z) SUBUNIT ALPHA GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 heterotrimeric G-protein#PC00117;G-protein#PC00020 Dopamine receptor mediated signaling pathway#P05912>GNAZ#P05964 LEPOC|Ensembl=ENSLOCG00000010280.1|UniProtKB=W5MW66 W5MW66 PTHR48092:SF12 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN RECEPTOR BETA sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676 cellular response to steroid hormone stimulus#GO:0071383;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;estrogen receptor signaling pathway#GO:0030520;response to endogenous stimulus#GO:0009719;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;response to steroid hormone#GO:0048545;intracellular receptor signaling pathway#GO:0030522;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000134.1|UniProtKB=W5LVI8 W5LVI8 PTHR24027:SF85 CADHERIN-23 CADHERIN-11 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell motility#GO:0048870;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell migration#GO:0016477;cellular component assembly#GO:0022607;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000017497.1|UniProtKB=W5NLU3 W5NLU3 PTHR14315:SF21 SPOT14 FAMILY MEMBER MID1-INTERACTING PROTEIN 1-LIKE regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of lipid biosynthetic process#GO:0046890;regulation of cellular process#GO:0050794;regulation of lipid metabolic process#GO:0019216;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013130.1|UniProtKB=W5N6B4 W5N6B4 PTHR46091:SF2 BLR7054 PROTEIN AMINE OXIDASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000018018.1|UniProtKB=W5NNB0 W5NNB0 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 14A ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017589.1|UniProtKB=W5NM35 W5NM35 PTHR21465:SF2 ZINC FINGER PROTEIN 469 ZINC FINGER PROTEIN 469 LEPOC|Ensembl=ENSLOCG00000014341.1|UniProtKB=W5NAK0 W5NAK0 PTHR22957:SF333 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 25 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein-containing complex disassembly#GO:0043244;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of macroautophagy#GO:0016241;regulation of autophagosome maturation#GO:1901096 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000005552.1|UniProtKB=W5ME95 W5ME95 PTHR10291:SF51 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;isoprenoid biosynthetic process#GO:0008299;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000005837.1|UniProtKB=W5MF93 W5MF93 PTHR18945:SF60 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT GAMMA monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 acetylcholine receptor signaling pathway#GO:0095500;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;transport#GO:0006810;muscle contraction#GO:0006936;establishment of localization#GO:0051234;system process#GO:0003008;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;striated muscle contraction#GO:0006941;trans-synaptic signaling#GO:0099537;neuromuscular process#GO:0050905;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;response to nitrogen compound#GO:1901698;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;muscle system process#GO:0003012;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;skeletal muscle contraction#GO:0003009;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;nervous system process#GO:0050877;response to oxygen-containing compound#GO:1901700;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transporter complex#GO:1990351;cell junction#GO:0030054;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>gamma#P01094 LEPOC|Ensembl=ENSLOCG00000000007.1|UniProtKB=W5LV51 W5LV51 PTHR13904:SF0 PRE-MRNA SPLICING FACTOR PRP31 U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000003744.1|UniProtKB=W5M7X6 W5M7X6 PTHR15711:SF73 RAP GTPASE-ACTIVATING PROTEIN RAP1 GTPASE-ACTIVATING PROTEIN 1-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;axon#GO:0030424 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000002448.1|UniProtKB=W5M3B6 W5M3B6 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016642.1|UniProtKB=W5NIV0 W5NIV0 PTHR12286:SF5 SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137 intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009376.1|UniProtKB=W5MSS5 W5MSS5 PTHR32247:SF4 DIABLO HOMOLOG, MITOCHONDRIAL DIRECT IAP-BINDING PROTEIN WITH LOW PI apoptotic signaling pathway#GO:0097190;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;neuron apoptotic process#GO:0051402;intrinsic apoptotic signaling pathway#GO:0097193;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011498.1|UniProtKB=W5N0H5 W5N0H5 PTHR24416:SF485 TYROSINE-PROTEIN KINASE RECEPTOR PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009158.1|UniProtKB=W5MS16 W5MS16 PTHR35971:SF5 SI:DKEY-31G6.6 OBSCURIN LIKE CYTOSKELETAL ADAPTOR 1 LEPOC|Ensembl=ENSLOCG00000015291.1|UniProtKB=W5NDV3 W5NDV3 PTHR45716:SF4 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 4 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810 cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007441.1|UniProtKB=W5MKW6 W5MKW6 PTHR16083:SF95 LEUCINE RICH REPEAT CONTAINING PROTEIN RAS SUPPRESSOR PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016961.1|UniProtKB=W5NK09 W5NK09 PTHR45740:SF13 POLY [ADP-RIBOSE] POLYMERASE POLY (ADP-RIBOSE) POLYMERASE FAMILY, MEMBER 12B glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012758.1|UniProtKB=W5N502 W5N502 PTHR21355:SF19 G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 G PROTEIN-COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012461.1|UniProtKB=W5N3Y4 W5N3Y4 PTHR10695:SF60 DEPHOSPHO-COA KINASE-RELATED BIFUNCTIONAL COENZYME A SYNTHASE adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000009890.1|UniProtKB=W5MUM9 W5MUM9 PTHR10903:SF170 GTPASE, IMAP FAMILY MEMBER-RELATED AIG1-TYPE G DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000003570.1|UniProtKB=W5M776 W5M776 PTHR11785:SF515 AMINO ACID TRANSPORTER LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 1 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;transport#GO:0006810;amino acid transport#GO:0006865 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000603.1|UniProtKB=W5LX05 W5LX05 PTHR46708:SF7 TENASCIN FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN carbohydrate derivative binding#GO:0097367;signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877 multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell-substrate junction organization#GO:0150115;cell junction organization#GO:0034330;circulatory system development#GO:0072359;cellular component organization#GO:0016043;cell-substrate junction assembly#GO:0007044;cell junction assembly#GO:0034329;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000010544.1|UniProtKB=W5MX11 W5MX11 PTHR10476:SF72 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2B vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;late endosome to vacuole transport#GO:0045324;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011146.1|UniProtKB=W5MZ88 W5MZ88 PTHR18964:SF176 ROK (REPRESSOR, ORF, KINASE) FAMILY BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;isomerase activity#GO:0016853 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000005354.1|UniProtKB=W5MDJ9 W5MDJ9 PTHR43570:SF9 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER A2 catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity#GO:0016491 aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;metabolic process#GO:0008152 membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000003490.1|UniProtKB=W5M6Y3 W5M6Y3 PTHR10848:SF0 MEIOTIC RECOMBINATION PROTEIN SPO11 MEIOTIC RECOMBINATION PROTEIN SPO11 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;homologous recombination#GO:0035825;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;organelle organization#GO:0006996;meiotic DNA double-strand break formation#GO:0042138;response to stress#GO:0006950;cellular process#GO:0009987;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000001386.1|UniProtKB=W5LZN5 W5LZN5 PTHR42884:SF39 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 1 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 hormone metabolic process#GO:0042445;gene expression#GO:0010467;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein processing#GO:0016485;peptide hormone processing#GO:0016486;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;proteolysis#GO:0006508 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Endothelin signaling pathway#P00019>furin#P00575;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 LEPOC|Ensembl=ENSLOCG00000006323.1|UniProtKB=W5MGY2 W5MGY2 PTHR23193:SF21 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP214 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198;molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 establishment of RNA localization#GO:0051236;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;transport#GO:0006810;intracellular protein transport#GO:0006886;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015356.1|UniProtKB=W5NE45 W5NE45 PTHR33487:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 54 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 54 cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006711.1|UniProtKB=W5MI95 W5MI95 PTHR24416:SF134 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR1 transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of intracellular signal transduction#GO:1902533;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 axon#GO:0030424;signaling receptor complex#GO:0043235;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014811.1|UniProtKB=W5NC81 W5NC81 PTHR47980:SF6 LD44762P RAS-RELATED PROTEIN RAB-8B endocytic recycling#GO:0032456;export from cell#GO:0140352;localization within membrane#GO:0051668;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;secretion by cell#GO:0032940;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;endosomal transport#GO:0016197 Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004416.1|UniProtKB=W5MA64 W5MA64 PTHR24256:SF524 TRYPTASE-RELATED HAPTOGLOBIN ISOFORM X1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000014754.1|UniProtKB=W5NC08 W5NC08 PTHR19305:SF22 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;membrane fusion#GO:0061025;synaptic vesicle membrane organization#GO:0048499;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;anterograde trans-synaptic signaling#GO:0098916;vesicle fusion#GO:0006906;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;vesicle fusion to plasma membrane#GO:0099500;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular localization#GO:0051641;secretion by cell#GO:0032940;export from cell#GO:0140352;signaling#GO:0023052;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150;SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000000595.1|UniProtKB=W5LX02 W5LX02 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000013033.1|UniProtKB=W5N604 W5N604 PTHR10132:SF16 ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER ALPHA-SARCOGLYCAN plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000010766.1|UniProtKB=W5MXT2 W5MXT2 PTHR15706:SF26 SH3 MULTIPLE DOMAIN SH3 AND PX DOMAIN-CONTAINING PROTEIN 2B enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 superoxide metabolic process#GO:0006801;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012472.1|UniProtKB=W5N3Z6 W5N3Z6 PTHR35082:SF1 BEN DOMAIN-CONTAINING PROTEIN 4 BEN DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000000282.1|UniProtKB=W5LW00 W5LW00 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000009997.1|UniProtKB=W5MV14 W5MV14 PTHR12040:SF22 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1B histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000025.1|UniProtKB=W5LV72 W5LV72 PTHR24247:SF116 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 7 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594 G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794 dendrite#GO:0030425;dendritic tree#GO:0097447;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000003936.1|UniProtKB=W5M8K3 W5M8K3 PTHR11640:SF51 NEPHRIN KIN OF IRRE-LIKE PROTEIN 2 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005301.1|UniProtKB=W5MDD2 W5MDD2 PTHR21468:SF1 HSD9 COILED-COIL DOMAIN-CONTAINING PROTEIN 83 LEPOC|Ensembl=ENSLOCG00000012322.1|UniProtKB=W5N3F7 W5N3F7 PTHR10306:SF9 SYNAPTOPHYSIN SYNAPTOPHYSIN-LIKE PROTEIN 1 cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle#GO:0030133;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000012502.1|UniProtKB=W5N429 W5N429 PTHR15126:SF4 SH3-BINDING SH3 DOMAIN-BINDING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000012520.1|UniProtKB=W5N468 W5N468 PTHR13605:SF4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7 ENDOPLASMIC RETICULUM MEMBRANE PROTEIN COMPLEX SUBUNIT 7 EMC complex#GO:0072546;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000008639.1|UniProtKB=W5MQ39 W5MQ39 PTHR22802:SF475 C-TYPE LECTIN SUPERFAMILY MEMBER CD302 ANTIGEN signaling receptor activity#GO:0038023;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011074.1|UniProtKB=W5MYY7 W5MYY7 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009600.1|UniProtKB=W5MTM4 W5MTM4 PTHR10924:SF6 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER A3 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000002115.1|UniProtKB=W5M255 W5M255 PTHR11468:SF32 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, MUSCLE FORM glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;generation of precursor metabolites and energy#GO:0006091;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;glycogen catabolic process#GO:0005980;cellular process#GO:0009987;energy reserve metabolic process#GO:0006112;carbohydrate catabolic process#GO:0016052;glycogen metabolic process#GO:0005977;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;polysaccharide catabolic process#GO:0000272;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 LEPOC|Ensembl=ENSLOCG00000004175.1|UniProtKB=W5M9E4 W5M9E4 PTHR12247:SF130 POLYCOMB GROUP PROTEIN L3MBTL HISTONE METHYL-LYSINE BINDING PROTEIN 4 protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006372.1|UniProtKB=W5MH36 W5MH36 PTHR11461:SF84 SERINE PROTEASE INHIBITOR, SERPIN PIGMENT EPITHELIUM-DERIVED FACTOR endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of angiogenesis#GO:0045765;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of angiogenesis#GO:0016525;regulation of vasculature development#GO:1901342 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000008703.1|UniProtKB=W5MQD4 W5MQD4 PTHR12929:SF1 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 nitrogen compound transport#GO:0071705;transport#GO:0006810;vitamin transport#GO:0051180;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009306.1|UniProtKB=W5MSJ4 W5MSJ4 PTHR11599:SF16 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-2 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;proteasome complex#GO:0000502 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000004025.1|UniProtKB=W5M8V5 W5M8V5 PTHR10528:SF6 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;system process#GO:0003008;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;DNA-templated transcription elongation#GO:0006354;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;RNA metabolic process#GO:0016070;nervous system process#GO:0050877;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009039.1|UniProtKB=W5MRK5 W5MRK5 PTHR31109:SF2 PROTEIN FAM207A RIBOSOME BIOGENESIS PROTEIN SLX9 HOMOLOG LEPOC|Ensembl=ENSLOCG00000010447.1|UniProtKB=W5MWP4 W5MWP4 PTHR22930:SF312 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002339.1|UniProtKB=W5M2Y5 W5M2Y5 PTHR10827:SF98 RETICULOCALBIN 45 KDA CALCIUM-BINDING PROTEIN binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calmodulin-related#PC00061;calcium-binding protein#PC00060 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 LEPOC|Ensembl=ENSLOCG00000010454.1|UniProtKB=W5MWQ4 W5MWQ4 PTHR14239:SF3 DUDULIN-RELATED STEAP FAMILY MEMBER 1B-RELATED oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491;ferric-chelate reductase activity#GO:0000293;catalytic activity#GO:0003824 transition metal ion transport#GO:0000041;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020 reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000013652.1|UniProtKB=W5N874 W5N874 PTHR12649:SF29 PEPTIDYL-TRNA HYDROLASE 2 PEPTIDYL-TRNA HYDROLASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000018262.1|UniProtKB=W5NP04 W5NP04 PTHR22650:SF6 GLYCOPROTEIN IB BETA PLATELET GLYCOPROTEIN IX Blood coagulation#P00011>GP IX#P00455 LEPOC|Ensembl=ENSLOCG00000007310.1|UniProtKB=W5MKE2 W5MKE2 PTHR15237:SF2 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9B intracellular signal transduction#GO:0035556;cell communication#GO:0007154;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;response to radiation#GO:0009314;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;DNA integrity checkpoint signaling#GO:0031570;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;response to ionizing radiation#GO:0010212;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;response to abiotic stimulus#GO:0009628;cellular response to radiation#GO:0071478;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786;cellular response to abiotic stimulus#GO:0071214;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 exodeoxyribonuclease#PC00098 LEPOC|Ensembl=ENSLOCG00000008825.1|UniProtKB=W5MQS6 W5MQS6 PTHR11636:SF41 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007971.1|UniProtKB=W5MMS2 W5MMS2 PTHR23112:SF51 G PROTEIN-COUPLED RECEPTOR 157-RELATED TRANSMEMBRANE PROTEIN 116 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010283.1|UniProtKB=W5MW60 W5MW60 PTHR18934:SF229 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX30 ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;helicase activity#GO:0004386 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007803.1|UniProtKB=W5MM58 W5MM58 PTHR11848:SF78 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 15 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000006012.1|UniProtKB=W5MFV6 W5MFV6 PTHR24068:SF177 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 2 ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 response to stimulus#GO:0050896;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000003462.1|UniProtKB=W5M6U8 W5M6U8 PTHR28634:SF1 ZINC FINGER B-BOX DOMAIN-CONTAINING PROTEIN 1 ZINC FINGER B-BOX DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000000508.1|UniProtKB=W5LWQ5 W5LWQ5 PTHR12483:SF22 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS HIGH AFFINITY COPPER UPTAKE PROTEIN 1 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;metal ion transport#GO:0030001;copper ion transmembrane transport#GO:0035434;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;transition metal ion transport#GO:0000041;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013572.1|UniProtKB=W5N7X1 W5N7X1 PTHR45734:SF3 TENSIN TENSIN-1 cell migration#GO:0016477;cell motility#GO:0048870;cellular process#GO:0009987 anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000001309.1|UniProtKB=W5LZD5 W5LZD5 PTHR15434:SF2 HEAT SHOCK FACTOR 2-BINDING PROTEIN HEAT SHOCK FACTOR 2-BINDING PROTEIN LEPOC|Ensembl=ENSLOCG00000011576.1|UniProtKB=W5N0R3 W5N0R3 PTHR24412:SF435 KELCH PROTEIN KELCH-LIKE PROTEIN 7 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001171.1|UniProtKB=W5LYV7 W5LYV7 PTHR36982:SF3 CLCA DOMAIN-CONTAINING PROTEIN SMALL INTEGRAL MEMBRANE PROTEIN 22 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000004880.1|UniProtKB=W5MBV9 W5MBV9 PTHR24300:SF319 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;tetrapyrrole binding#GO:0046906;binding#GO:0005488 cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000013676.1|UniProtKB=W5N8A5 W5N8A5 PTHR13793:SF90 PHD FINGER PROTEINS PROTEIN AF-17 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000749.1|UniProtKB=W5LXH5 W5LXH5 PTHR10972:SF205 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 1 sterol binding#GO:0032934;binding#GO:0005488;lipid binding#GO:0008289;steroid binding#GO:0005496 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000013461.1|UniProtKB=W5N7I8 W5N7I8 PTHR48125:SF12 LP07818P1 CONSERVED GLUTAMIC ACID RICH PROTEIN (AFU_ORTHOLOGUE AFUA_5G09010)-RELATED Cytoskeletal regulation by Rho GTPase#P00016>N-WASP#P00525;Huntington disease#P00029>N-Wasp#P00769 LEPOC|Ensembl=ENSLOCG00000002948.1|UniProtKB=W5M523 W5M523 PTHR14234:SF23 RIM BINDING PROTEIN-RELATED PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR-ASSOCIATED PROTEIN 1 ISOFORM X1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006885.1|UniProtKB=W5MIW9 W5MIW9 PTHR22880:SF143 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000007951.1|UniProtKB=W5MMQ0 W5MMQ0 PTHR23112:SF0 G PROTEIN-COUPLED RECEPTOR 157-RELATED SI:DKEY-100N23.5 ISOFORM X1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005205.1|UniProtKB=W5MD05 W5MD05 PTHR32178:SF8 FAM187 PROTEIN FAM187B immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005866.1|UniProtKB=W5MFC5 W5MFC5 PTHR15887:SF1 TRANSMEMBRANE PROTEIN 69 TRANSMEMBRANE PROTEIN 69 LEPOC|Ensembl=ENSLOCG00000004075.1|UniProtKB=W5M910 W5M910 PTHR22808:SF32 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 5-CYTOSINE RRNA METHYLTRANSFERASE NSUN4 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;macromolecule modification#GO:0043412;mitochondrial RNA metabolic process#GO:0000959;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;mitochondrial large ribosomal subunit assembly#GO:1902775;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial ribosome assembly#GO:0061668;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;ribosomal large subunit assembly#GO:0000027;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;mitochondrial RNA modification#GO:1900864;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000015147.1|UniProtKB=W5NDD2 W5NDD2 PTHR14200:SF11 CYTOCHROME C OXIDASE POLYPEPTIDE CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000004843.1|UniProtKB=W5MBR1 W5MBR1 PTHR24064:SF470 SOLUTE CARRIER FAMILY 22 MEMBER SI:DKEY-166K12.1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000000573.1|UniProtKB=W5LWX5 W5LWX5 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000347.1|UniProtKB=W5LW73 W5LW73 PTHR14905:SF18 NG37 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING 10, TANDEM DUPLICATE 1-RELATED LEPOC|Ensembl=ENSLOCG00000016401.1|UniProtKB=W5NHZ4 W5NHZ4 PTHR24107:SF27 YNEIN REGULATORY COMPLEX SUBUNIT 5 DYNEIN REGULATORY COMPLEX SUBUNIT 5 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012074.1|UniProtKB=W5N2J5 W5N2J5 PTHR46588:SF1 SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of cellular process#GO:0048523;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of catabolic process#GO:0009894;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000008230.1|UniProtKB=W5MNM8 W5MNM8 PTHR13308:SF23 NEDD4-BINDING PROTEIN 2-LIKE 1 NEDD4-BINDING PROTEIN 2-LIKE 2 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015435.1|UniProtKB=W5NED6 W5NED6 PTHR46144:SF3 ZINC FINGER PROTEIN 385B-LIKE ZINC FINGER MATRIN-TYPE PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000001423.1|UniProtKB=W5LZR4 W5LZR4 PTHR12258:SF11 JANUS-A/JANUS-B 14 KDA PHOSPHOHISTIDINE PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006544.1|UniProtKB=W5MHQ5 W5MHQ5 PTHR46097:SF1 G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP ARF GTPASE-ACTIVATING PROTEIN GIT1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme binding#GO:0019899;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;regulation of response to stimulus#GO:0048583;transport#GO:0006810;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of small GTPase mediated signal transduction#GO:0051056;multicellular organism development#GO:0007275;vesicle-mediated transport in synapse#GO:0099003;animal organ development#GO:0048513;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;nervous system development#GO:0007399;head development#GO:0060322;brain development#GO:0007420;synaptic vesicle recycling#GO:0036465;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;localization#GO:0051179;anatomical structure development#GO:0048856;cellular localization#GO:0051641;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794 neuron projection#GO:0043005;cytosol#GO:0005829;postsynapse#GO:0098794;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000011229.1|UniProtKB=W5MZI6 W5MZI6 PTHR24028:SF57 CADHERIN-87A PROTOCADHERIN ALPHA-C2 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000001508.1|UniProtKB=W5M010 W5M010 PTHR14845:SF0 COILED-COIL DOMAIN-CONTAINING 166 COILED-COIL DOMAIN CONTAINING 166 LEPOC|Ensembl=ENSLOCG00000010803.1|UniProtKB=W5MXY3 W5MXY3 PTHR11842:SF11 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;biological regulation#GO:0065007;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of cell cycle#GO:0045786;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of sister chromatid segregation#GO:0033046 membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776 LEPOC|Ensembl=ENSLOCG00000010556.1|UniProtKB=W5MX36 W5MX36 PTHR16062:SF19 SWI/SNF-RELATED PROTEIN POLYBROMO-1 binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 RSC-type complex#GO:0016586;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000007483.1|UniProtKB=W5ML24 W5ML24 PTHR43143:SF1 METALLOPHOSPHOESTERASE, CALCINEURIN SUPERFAMILY SERINE_THREONINE-PROTEIN PHOSPHATASE CPPED1 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011016.1|UniProtKB=W5MYR5 W5MYR5 PTHR24418:SF90 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE YES phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Yes#P00476;Parkinson disease#P00049>Src kinase#P01230;CCKR signaling map#P06959>YES1#P07142 LEPOC|Ensembl=ENSLOCG00000012761.1|UniProtKB=W5N4Z6 W5N4Z6 PTHR42790:SF24 AMINOTRANSFERASE KYNURENINE_ALPHA-AMINOADIPATE AMINOTRANSFERASE, MITOCHONDRIAL transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000008974.1|UniProtKB=W5MRC6 W5MRC6 PTHR43651:SF15 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;glycogen biosynthetic process#GO:0005978;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;glucan biosynthetic process#GO:0009250;energy reserve metabolic process#GO:0006112;polysaccharide biosynthetic process#GO:0000271 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 amylase#PC00048 LEPOC|Ensembl=ENSLOCG00000008644.1|UniProtKB=W5MQ48 W5MQ48 PTHR24112:SF68 LEUCINE-RICH REPEAT, ISOFORM F-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 37 regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;cell migration#GO:0016477;cell motility#GO:0048870;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013994.1|UniProtKB=W5N9E6 W5N9E6 PTHR14269:SF43 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING 5 phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002196.1|UniProtKB=W5M2G0 W5M2G0 PTHR22589:SF50 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407 cellular process#GO:0009987;carnitine metabolic process#GO:0009437;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017752.1|UniProtKB=W5NMJ7 W5NMJ7 PTHR16100:SF5 PHOSPHOINOSITIDE-INTERACTING PROTEIN FAMILY MEMBER TRANSMEMBRANE PROTEIN 100 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;regulation of system process#GO:0044057;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000008099.1|UniProtKB=W5MN77 W5MN77 PTHR11986:SF126 AMINOTRANSFERASE CLASS III ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000007696.1|UniProtKB=W5MLU6 W5MLU6 PTHR14139:SF5 CALSYNTENIN CALSYNTENIN-3 protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 regulation of biological quality#GO:0065008;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;cell adhesion#GO:0007155;positive regulation of cellular component organization#GO:0051130;regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of synapse assembly#GO:0051965;positive regulation of developmental process#GO:0051094;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of synapse assembly#GO:0051963;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;cell surface#GO:0009986;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007400.1|UniProtKB=W5MKT7 W5MKT7 PTHR18896:SF57 PHOSPHOLIPASE D PHOSPHOLIPASE D1 phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;lipase activity#GO:0016298;hydrolase activity#GO:0016787 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of localization#GO:0032879;regulation of transport#GO:0051049;organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987;biological regulation#GO:0065007;organophosphate catabolic process#GO:0046434;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644 intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 lipase#PC00143;phospholipase#PC00186 Angiogenesis#P00005>PLD#P00204;Ras Pathway#P04393>PLD#P04574 LEPOC|Ensembl=ENSLOCG00000005464.1|UniProtKB=W5MDX9 W5MDX9 PTHR13318:SF179 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 15 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000001478.1|UniProtKB=W5M000 W5M000 PTHR12411:SF554 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN 12 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012372.1|UniProtKB=W5N3M1 W5N3M1 PTHR24072:SF325 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3 hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367 motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;signaling#GO:0023052;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;establishment or maintenance of cell polarity#GO:0007163;Rac protein signal transduction#GO:0016601;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;regulation of developmental process#GO:0050793;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;cortical cytoskeleton organization#GO:0030865;system development#GO:0048731;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;axon guidance#GO:0007411;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 small GTPase#PC00208;G-protein#PC00020 EGF receptor signaling pathway#P00018>Rac#P00564;T cell activation#P00053>rac#P01324;Ras Pathway#P04393>Rac#P04559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Integrin signalling pathway#P00034>Rac#P00927;Huntington disease#P00029>Rac#P00775;FGF signaling pathway#P00021>Rac#P00645;Axon guidance mediated by netrin#P00009>Rac#P00366;Axon guidance mediated by semaphorins#P00007>Rac#P00340;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;VEGF signaling pathway#P00056>Rac#P01421;B cell activation#P00010>Rac#P00385;p38 MAPK pathway#P05918>Rac#P06021;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354 LEPOC|Ensembl=ENSLOCG00000004650.1|UniProtKB=W5MB12 W5MB12 PTHR24096:SF435 LONG-CHAIN-FATTY-ACID--COA LIGASE MALONATE--COA LIGASE ACSF3, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000017959.1|UniProtKB=W5NN53 W5NN53 PTHR24366:SF189 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IMMUNOGLOBULIN SUPERFAMILY CONTAINING LEUCINE RICH REPEAT-RELATED immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005263.1|UniProtKB=W5MD94 W5MD94 PTHR24271:SF97 KALLIKREIN-RELATED MAST CELL PROTEASE 2 ISOFORM X1 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000006026.1|UniProtKB=W5MFX4 W5MFX4 PTHR11630:SF66 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM4 helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697 mitotic cell cycle process#GO:1903047;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA replication initiation#GO:0006270;DNA repair#GO:0006281;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA strand elongation involved in DNA replication#GO:0006271;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010223.1|UniProtKB=W5MVW1 W5MVW1 PTHR10405:SF15 SPINDLIN SPINDLIN-1 protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004589.1|UniProtKB=W5MAT7 W5MAT7 PTHR19317:SF0 PRENYLATED RAB ACCEPTOR 1-RELATED PRENYLATED RAB ACCEPTOR PROTEIN 1 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002203.1|UniProtKB=W5M2F3 W5M2F3 PTHR31195:SF2 GEO02494P1 GEO02494P1 LEPOC|Ensembl=ENSLOCG00000001830.1|UniProtKB=W5M159 W5M159 PTHR20531:SF1 N-ALPHA-ACETYLTRANSFERASE 40 N-ALPHA-ACETYLTRANSFERASE 40 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000004463.1|UniProtKB=W5MAC3 W5MAC3 PTHR10985:SF11 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION COFACTOR HES-6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000013785.1|UniProtKB=W5N8P7 W5N8P7 PTHR15876:SF8 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013145.1|UniProtKB=W5N6D0 W5N6D0 PTHR12414:SF7 GLIAL CELLS MISSING RELATED/GLIDE CHORION-SPECIFIC TRANSCRIPTION FACTOR GCMB DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;gliogenesis#GO:0042063;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000008420.1|UniProtKB=W5MPE5 W5MPE5 PTHR11827:SF58 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 2 monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108 establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;monoatomic anion transport#GO:0006820;sodium ion transport#GO:0006814 apical part of cell#GO:0045177;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cell body#GO:0044297;membrane#GO:0016020;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000004852.1|UniProtKB=W5MBS1 W5MBS1 PTHR11849:SF275 ETS FLI-1 PROTO-ONCOGENE, ETS TRANSCRIPTION FACTOR-RELATED SEQUENCE ISOFORM X1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000016158.1|UniProtKB=W5NH03 W5NH03 PTHR46864:SF1 LAFORIN LAFORIN catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000004525.1|UniProtKB=W5MAK4 W5MAK4 PTHR12161:SF5 IST1 FAMILY MEMBER IST1 HOMOLOG macromolecule localization#GO:0033036;localization#GO:0051179;intracellular protein localization#GO:0008104 LEPOC|Ensembl=ENSLOCG00000005162.1|UniProtKB=W5MCV6 W5MCV6 PTHR24241:SF4 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008806.1|UniProtKB=W5MQS5 W5MQS5 PTHR45024:SF2 DEHYDROGENASES, SHORT CHAIN SCP2 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;hydro-lyase activity#GO:0016836;oxidoreductase activity#GO:0016491;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000014708.1|UniProtKB=W5NBU6 W5NBU6 PTHR11304:SF17 EPHRIN EPHRIN-B1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008 plasma membrane region#GO:0098590;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 Angiogenesis#P00005>Eph#P00239 LEPOC|Ensembl=ENSLOCG00000003242.1|UniProtKB=W5M623 W5M623 PTHR24251:SF47 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN 2 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015698.1|UniProtKB=W5NFB8 W5NFB8 PTHR12839:SF7 NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2 REGULATOR OF NONSENSE TRANSCRIPTS 2 regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001814.1|UniProtKB=W5M150 W5M150 PTHR11905:SF38 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 33 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010083.1|UniProtKB=W5MVC2 W5MVC2 PTHR10901:SF3 TROPOMODULIN LEIOMODIN-3 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;system process#GO:0003008;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;muscle contraction#GO:0006936;developmental process#GO:0032502;multicellular organismal process#GO:0032501;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 contractile muscle fiber#GO:0043292;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;sarcomere#GO:0030017;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;A band#GO:0031672;organelle#GO:0043226;cellular anatomical structure#GO:0110165;M band#GO:0031430;intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000003812.1|UniProtKB=W5M842 W5M842 LYVE1 PTHR10225:SF2 HYALURONAN RECEPTOR LYMPHATIC VESSEL ENDOTHELIAL HYALURONIC ACID RECEPTOR 1 signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;organic acid binding#GO:0043177;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013990.1|UniProtKB=W5N9D9 W5N9D9 PTHR12002:SF74 CLAUDIN CLAUDIN-15 paracellular tight junction channel activity#GO:0160187;transporter activity#GO:0005215 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184;establishment of localization#GO:0051234;cell-cell junction organization#GO:0045216;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000014550.1|UniProtKB=W5NB97 W5NB97 PTHR34921:SF1 MEIOTIC RECOMBINATION PROTEIN REC114 MEIOTIC RECOMBINATION PROTEIN REC114 LEPOC|Ensembl=ENSLOCG00000007490.1|UniProtKB=W5ML32 W5ML32 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED binding#GO:0005488;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008175.1|UniProtKB=W5MNG1 W5MNG1 PTHR47051:SF1 NESTIN NESTIN cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;chemokine receptor binding#GO:0042379 regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of protein-containing complex disassembly#GO:0043244;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of organelle organization#GO:0010638;regulation of protein depolymerization#GO:1901879;positive regulation of cellular component organization#GO:0051130 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000009557.1|UniProtKB=W5MTI4 W5MTI4 PTHR24393:SF69 ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE MECOM sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000011965.1|UniProtKB=W5N259 W5N259 PTHR15109:SF3 AGAP004327-PA PROTEIN FAM193B membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000000650.1|UniProtKB=W5LX62 W5LX62 PTHR23043:SF24 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000007474.1|UniProtKB=W5ML19 W5ML19 PTHR21494:SF3 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 LEPOC|Ensembl=ENSLOCG00000006622.1|UniProtKB=W5MI14 W5MI14 PTHR22692:SF34 MYOSIN VII, XV MYOSIN VIIA actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000014217.1|UniProtKB=W5NA50 W5NA50 PTHR43380:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001443.1|UniProtKB=W5LZU5 W5LZU5 PTHR12688:SF2 DYNEIN LIGHT INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 LIGHT INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;cytoplasmic dynein complex#GO:0005868;membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;kinetochore#GO:0000776;dynein complex#GO:0030286;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000011223.1|UniProtKB=W5MZH6 W5MZH6 PTHR13160:SF4 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002247.1|UniProtKB=W5M2L0 W5M2L0 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015287.1|UniProtKB=W5NDV0 W5NDV0 PTHR22883:SF71 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC9 catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012221.1|UniProtKB=W5N330 W5N330 PTHR12631:SF8 ALPHA-L-IDURONIDASE ALPHA-L-IDURONIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001961.1|UniProtKB=W5M1L5 W5M1L5 PTHR12921:SF0 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;autophagy#GO:0006914;reticulophagy#GO:0061709;response to stress#GO:0006950;macroautophagy#GO:0016236;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;process utilizing autophagic mechanism#GO:0061919 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003828.1|UniProtKB=W5M870 W5M870 PTHR45954:SF2 LD33695P G PROTEIN-SIGNALING MODULATOR 1 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;binding#GO:0005488 establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;mitotic cell cycle process#GO:1903047;cytoskeleton organization#GO:0007010;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;microtubule cytoskeleton organization#GO:0000226;spindle localization#GO:0051653;cellular localization#GO:0051641;localization#GO:0051179;organelle localization#GO:0051640;establishment or maintenance of cell polarity#GO:0007163;establishment of organelle localization#GO:0051656;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell cycle process#GO:0022402;establishment of cell polarity#GO:0030010 cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>AGS3#P00715;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>AGS3#P00739 LEPOC|Ensembl=ENSLOCG00000013833.1|UniProtKB=W5N8V6 W5N8V6 PTHR45832:SF11 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000000043.1|UniProtKB=W5LV94 W5LV94 PTHR45622:SF56 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HECTD2-RELATED ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000005891.1|UniProtKB=W5MFF7 W5MFF7 PTHR15350:SF5 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 SIGNALOSOME COMPLEX SUBUNIT 7 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011014.1|UniProtKB=W5MYR2 W5MYR2 PTHR22600:SF38 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE SUBUNIT BETA catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 sphingolipid catabolic process#GO:0030149;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;carbohydrate derivative catabolic process#GO:1901136;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;ceramide metabolic process#GO:0006672;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;lysosome#GO:0005764;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;extracellular region#GO:0005576;intracellular organelle#GO:0043229 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000000676.1|UniProtKB=W5LX89 W5LX89 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 antigen binding#GO:0003823;binding#GO:0005488 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014795.1|UniProtKB=W5NC60 W5NC60 PTHR32003:SF1 PROTEIN FAM199X PROTEIN FAM199X LEPOC|Ensembl=ENSLOCG00000000717.1|UniProtKB=W5LXE5 W5LXE5 PTHR21551:SF2 TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1 PROTEIN PAT1 HOMOLOG 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cellular component assembly#GO:0022607;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA catabolic process#GO:0061013;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;organelle assembly#GO:0070925;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;organelle organization#GO:0006996;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;P-body assembly#GO:0033962;primary metabolic process#GO:0044238;negative regulation of protein metabolic process#GO:0051248;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;RNA decapping#GO:0110154 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;P-body#GO:0000932;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000014174.1|UniProtKB=W5NA08 W5NA08 PTHR35478:SF1 ZINC FINGER FYVE DOMAIN PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 26 LEPOC|Ensembl=ENSLOCG00000015658.1|UniProtKB=W5NF64 W5NF64 PTHR16483:SF1 GASTROKINE 1 GASTROKINE-1 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000008774.1|UniProtKB=W5MQL7 W5MQL7 PTHR24068:SF72 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2Q-LIKE PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015203.1|UniProtKB=W5NDK7 W5NDK7 PTHR23119:SF28 DISCS LARGE DISKS LARGE HOMOLOG 3 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;binding#GO:0005488;structural constituent of synapse#GO:0098918;protein binding#GO:0005515;structural molecule activity#GO:0005198 nervous system development#GO:0007399;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;multicellular organism development#GO:0007275;protein localization to synapse#GO:0035418;signaling#GO:0023052;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;receptor clustering#GO:0043113;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;developmental process#GO:0032502;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;localization#GO:0051179;cell communication#GO:0007154;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;anatomical structure development#GO:0048856;system development#GO:0048731;protein localization to cell junction#GO:1902414;establishment or maintenance of apical/basal cell polarity#GO:0035088;trans-synaptic signaling#GO:0099537;localization within membrane#GO:0051668;establishment or maintenance of bipolar cell polarity#GO:0061245 neuromuscular junction#GO:0031594;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010452.1|UniProtKB=W5MWQ9 W5MWQ9 PTHR15288:SF6 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2C GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000001402.1|UniProtKB=W5LZP2 W5LZP2 PTHR14932:SF1 RAS GTPASE-RELATED RAB-LIKE PROTEIN 6 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000013788.1|UniProtKB=W5N8P9 W5N8P9 PTHR21346:SF5 FUN14 DOMAIN CONTAINING FUN14 DOMAIN-CONTAINING PROTEIN 2 catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;autophagy#GO:0006914;cellular process#GO:0009987 mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007390.1|UniProtKB=W5MKR4 W5MKR4 PTHR12790:SF0 TRANSCRIPTION INITIATION FACTOR IA RRN3 RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription initiation at RNA polymerase I promoter#GO:0006361;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 LEPOC|Ensembl=ENSLOCG00000003799.1|UniProtKB=W5M824 W5M824 PTHR43917:SF10 FAMILY NOT NAMED GLUTATHIONE TRANSFERASE glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000017098.1|UniProtKB=W5NKH0 W5NKH0 PTHR14401:SF6 CENTROMERE PROTEIN K CENTROMERE PROTEIN K LEPOC|Ensembl=ENSLOCG00000009733.1|UniProtKB=W5MU28 W5MU28 PTHR45834:SF8 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017578.1|UniProtKB=W5NM24 W5NM24 PTHR24559:SF466 TRANSPOSON TY3-I GAG-POL POLYPROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000004894.1|UniProtKB=W5MBY6 W5MBY6 PTHR16308:SF19 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER UBIQUITIN-ASSOCIATED PROTEIN 2 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000017344.1|UniProtKB=W5NLE0 W5NLE0 PTHR25464:SF6 TRIPARTITE MOTIF-CONTAINING PROTEIN 2-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE TRIM32 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;positive regulation of cytokine-mediated signaling pathway#GO:0001961;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;regulation of cytokine-mediated signaling pathway#GO:0001959;cellular response to amino acid starvation#GO:0034198;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of autophagy#GO:0010508;regulation of response to cytokine stimulus#GO:0060759;response to stress#GO:0006950 LEPOC|Ensembl=ENSLOCG00000000274.1|UniProtKB=W5LVZ2 W5LVZ2 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000003932.1|UniProtKB=W5M8J4 W5M8J4 PTHR24056:SF129 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 4 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012959.1|UniProtKB=W5N5U0 W5N5U0 PTHR23078:SF3 VESICULAR-FUSION PROTEIN NSF VESICLE-FUSING ATPASE pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887 establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641 Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>NSF#P05774;Ionotropic glutamate receptor pathway#P00037>NSF#P01020 LEPOC|Ensembl=ENSLOCG00000008217.1|UniProtKB=W5MNL7 W5MNL7 PTHR15284:SF1 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;circadian rhythm#GO:0007623;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;rhythmic process#GO:0048511 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000017315.1|UniProtKB=W5NLB1 W5NLB1 PTHR10960:SF0 V D J RECOMBINATION-ACTIVATING PROTEIN 2 V(D)J RECOMBINATION-ACTIVATING PROTEIN 2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565 macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;DNA recombination#GO:0006310;developmental process#GO:0032502;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;somatic cell DNA recombination#GO:0016444;nucleobase-containing compound metabolic process#GO:0006139;multicellular organismal process#GO:0032501;cellular process#GO:0009987;system development#GO:0048731;anatomical structure development#GO:0048856;immune system development#GO:0002520;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;somatic diversification of immune receptors#GO:0002200;V(D)J recombination#GO:0033151;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993 LEPOC|Ensembl=ENSLOCG00000010962.1|UniProtKB=W5MYJ1 W5MYJ1 PTHR10985:SF3 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 40 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000004972.1|UniProtKB=W5MC96 W5MC96 PTHR15565:SF0 AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR PROTEIN AATF macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000018184.1|UniProtKB=W5NNS6 W5NNS6 PTHR24226:SF6 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 ADRENOMEDULLIN RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008392.1|UniProtKB=W5MP94 W5MP94 PTHR45720:SF4 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic anion channel activity#GO:0008308;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253 monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001006.1|UniProtKB=W5LYC5 W5LYC5 PTHR24064:SF216 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 17 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;iron coordination entity transport#GO:1901678;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;metal ion transport#GO:0030001;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000015724.1|UniProtKB=W5NFE6 W5NFE6 PTHR45873:SF1 DNA POLYMERASE ETA DNA POLYMERASE ETA DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA-directed DNA polymerase activity#GO:0003887 DNA synthesis involved in DNA replication#GO:0090592;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to abiotic stimulus#GO:0009628;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;DNA biosynthetic process#GO:0071897;response to radiation#GO:0009314;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950 chromosome#GO:0005694;site of double-strand break#GO:0035861;nucleus#GO:0005634;replication fork#GO:0005657;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010548.1|UniProtKB=W5MX19 W5MX19 PTHR24056:SF154 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 14 catalytic activity, acting on a protein#GO:0140096;cyclin binding#GO:0030332;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;cyclin-dependent protein kinase activity#GO:0097472 mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cell cycle G2/M phase transition#GO:0044839;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086 cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex#GO:1990234;protein kinase complex#GO:1902911;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011031.1|UniProtKB=W5MYT6 W5MYT6 PTHR21963:SF1 PF6 SPERM-ASSOCIATED ANTIGEN 17 cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cilium movement#GO:0003341;microtubule bundle formation#GO:0001578;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017 plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;axonemal central apparatus#GO:1990716 LEPOC|Ensembl=ENSLOCG00000009222.1|UniProtKB=W5MS92 W5MS92 PTHR11551:SF4 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 5 binding#GO:0005488;protein binding#GO:0005515;growth factor binding#GO:0019838 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002845.1|UniProtKB=W5M4P5 W5M4P5 PTHR11728:SF46 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)] oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000000124.1|UniProtKB=W5LVH8 W5LVH8 PTHR13169:SF0 UBIQUITIN-LIKE PROTEIN 3 HCG-1 PROTEIN UBIQUITIN-LIKE PROTEIN 3 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000006695.1|UniProtKB=W5MI73 W5MI73 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008152.1|UniProtKB=W5MND9 W5MND9 PTHR43313:SF52 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 9 alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;cellular process#GO:0009987;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000015820.1|UniProtKB=W5NFR6 W5NFR6 PTHR10151:SF79 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE BIS(5'-ADENOSYL)-TRIPHOSPHATASE ENPP4 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007849.1|UniProtKB=W5MMC1 W5MMC1 PTHR11972:SF60 NADPH OXIDASE NADPH OXIDASE 2 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801;defense response#GO:0006952;response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000010826.1|UniProtKB=W5MY06 W5MY06 PTHR11177:SF407 CHITINASE CHITOTRIOSIDASE-1 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006834.1|UniProtKB=W5MIQ4 W5MIQ4 PTHR15739:SF2 ZINC FINGER PROTEIN PROTEIN ZNF365 regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344;regulation of response to stress#GO:0080134;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;telomere organization#GO:0032200;regulation of double-strand break repair#GO:2000779;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of DNA recombination#GO:0000018;regulation of cellular response to stress#GO:0080135;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cellular component organization#GO:0016043;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of cellular component organization#GO:0051128 LEPOC|Ensembl=ENSLOCG00000015426.1|UniProtKB=W5NEC3 W5NEC3 PTHR35450:SF2 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN C1Q DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017817.1|UniProtKB=W5NLZ4 W5NLZ4 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000008996.1|UniProtKB=W5MRF2 W5MRF2 PTHR45960:SF5 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 1 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Grb2#P01148;EGF receptor signaling pathway#P00018>Gab#P00563 LEPOC|Ensembl=ENSLOCG00000018002.1|UniProtKB=W5NN94 W5NN94 PTHR46341:SF1 PROTEIN FAM84B-RELATED PROTEIN LRATD1 anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;cellular process#GO:0009987;cell motility#GO:0048870;cell morphogenesis#GO:0000902;anatomical structure development#GO:0048856 LEPOC|Ensembl=ENSLOCG00000002897.1|UniProtKB=W5M4U5 W5M4U5 PTHR24083:SF44 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP F MEMBER 6 transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837 animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000010895.1|UniProtKB=W5MY99 W5MY99 EEF1AKMT1 PTHR13200:SF0 EEF1A LYSINE METHYLTRANSFERASE 1 EEF1A LYSINE METHYLTRANSFERASE 1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170 LEPOC|Ensembl=ENSLOCG00000013969.1|UniProtKB=W5N9A9 W5N9A9 PTHR13932:SF5 COPROPORPHYRINIGEN III OXIDASE RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 porphyrin-containing compound biosynthetic process#GO:0006779;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound metabolic process#GO:0006778;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidase#PC00175 Heme biosynthesis#P02746>Coproporphyrinogen oxidase (oxygen independent)#P02970 LEPOC|Ensembl=ENSLOCG00000002048.1|UniProtKB=W5M1Y4 W5M1Y4 PTHR43740:SF3 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;translation#GO:0006412;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006928.1|UniProtKB=W5MJ21 W5MJ21 PTHR23302:SF42 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 7 channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000007373.1|UniProtKB=W5MKN0 W5MKN0 PTHR21694:SF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 LEPOC|Ensembl=ENSLOCG00000011188.1|UniProtKB=W5MZD6 W5MZD6 PTHR12765:SF5 RED PROTEIN IK FACTOR CYTOKINE IK PROTEIN RED mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000017603.1|UniProtKB=W5NM49 W5NM49 PTHR24230:SF128 G-PROTEIN COUPLED RECEPTOR BLT1-LIKE1 PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015447.1|UniProtKB=W5NEF4 W5NEF4 PTHR45671:SF10 SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 3 active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;phosphate transmembrane transporter activity#GO:0005315;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;transport#GO:0006810;cellular process#GO:0009987 mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 mitochondrial carrier protein#PC00158 LEPOC|Ensembl=ENSLOCG00000010216.1|UniProtKB=W5MVW5 W5MVW5 PTHR24033:SF151 EGF-LIKE DOMAIN-CONTAINING PROTEIN NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000009657.1|UniProtKB=W5MTU2 W5MTU2 PTHR24240:SF138 OPSIN NOVOPSIN-2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to radiation#GO:0071478;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;signal transduction#GO:0007165;response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;detection of stimulus#GO:0051606;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002075.1|UniProtKB=W5M215 W5M215 PTHR24103:SF667 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM69 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000544.1|UniProtKB=W5M7K7 W5M7K7 PTHR24384:SF254 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 628 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015388.1|UniProtKB=W5NE76 W5NE76 PTHR28590:SF2 SPEXIN SPEXIN PROHORMONE 1 LEPOC|Ensembl=ENSLOCG00000017416.1|UniProtKB=W5NLL2 W5NLL2 PTHR12002:SF99 CLAUDIN CLAUDIN-14 cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000007648.1|UniProtKB=W5MLL9 W5MLL9 PTHR11955:SF74 FATTY ACID BINDING PROTEIN RETINOL-BINDING PROTEIN 5 fatty acid binding#GO:0005504;lipid binding#GO:0008289;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;organic acid binding#GO:0043177 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000005078.1|UniProtKB=W5MCK7 W5MCK7 PTHR28532:SF1 GEO13458P1 LTO1 MATURATION FACTOR OF ABCE1 LEPOC|Ensembl=ENSLOCG00000014263.1|UniProtKB=W5NA98 W5NA98 PTHR14359:SF6 HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE carboxy-lyase activity#GO:0016831;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;lyase activity#GO:0016829 organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Coenzyme A biosynthesis#P02736>Pantothenoylcysteine decarboxylase#P02883;Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882 LEPOC|Ensembl=ENSLOCG00000008842.1|UniProtKB=W5MQV2 W5MQV2 PTHR11211:SF15 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015718.1|UniProtKB=W5NFD9 W5NFD9 PTHR15681:SF1 MAD2L1-BINDING PROTEIN MAD2L1-BINDING PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002229.1|UniProtKB=W5M2K4 W5M2K4 PTHR10290:SF24 DNA TOPOISOMERASE I DNA TOPOISOMERASE I catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853 chromosome segregation#GO:0007059;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cell cycle process#GO:0022402;DNA replication#GO:0006260;cell cycle#GO:0007049;organelle organization#GO:0006996;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DNA topoisomerase#PC00017;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000013693.1|UniProtKB=W5N8C2 W5N8C2 PTHR12345:SF12 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 2 peptide binding#GO:0042277;binding#GO:0005488 synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular process#GO:0009987;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;dendritic spine#GO:0043197;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093;Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084 LEPOC|Ensembl=ENSLOCG00000000625.1|UniProtKB=W5LX34 W5LX34 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010567.1|UniProtKB=W5MX39 W5MX39 PTHR45831:SF1 LD24721P SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN BETA post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;cellular localization#GO:0051641;establishment of localization#GO:0051234;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000000040.1|UniProtKB=W5LV89 W5LV89 PTHR45893:SF6 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 5 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;PcG protein complex#GO:0031519;nucleus#GO:0005634 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012691.1|UniProtKB=W5N4Q9 W5N4Q9 PTHR17613:SF9 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAINS PROTEIN 2 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000013736.1|UniProtKB=W5N8I3 W5N8I3 PTHR10155:SF5 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 response to hormone#GO:0009725;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cellular response to peptide hormone stimulus#GO:0071375;cellular response to chemical stimulus#GO:0070887;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 LEPOC|Ensembl=ENSLOCG00000002107.1|UniProtKB=W5M244 W5M244 PTHR10033:SF14 CALSEQUESTRIN CALSEQUESTRIN-1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;molecular sequestering activity#GO:0140313;ion binding#GO:0043167 regulation of release of sequestered calcium ion into cytosol#GO:0051279;calcium-mediated signaling#GO:0019722;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of system process#GO:0044057;regulation of monoatomic cation transmembrane transport#GO:1904062;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of monoatomic ion transport#GO:0043269;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of muscle contraction#GO:0006937;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;regulation of muscle system process#GO:0090257 I band#GO:0031674;endoplasmic reticulum#GO:0005783;sarcomere#GO:0030017;membraneless organelle#GO:0043228;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;sarcoplasmic reticulum#GO:0016529;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;myofibril#GO:0030016;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000007463.1|UniProtKB=W5ML18 W5ML18 PTHR23412:SF21 STEREOCILIN RELATED OTOANCORIN cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002244.1|UniProtKB=W5M2S4 W5M2S4 PTHR23180:SF407 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;neuron migration#GO:0001764;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell projection organization#GO:0031344;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;organelle organization#GO:0006996 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000000115.1|UniProtKB=W5LVH0 W5LVH0 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012568.1|UniProtKB=W5N4C2 W5N4C2 PTHR45888:SF1 HL01030P-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE 2C histone H3K4 methyltransferase activity#GO:0042800;histone H3 methyltransferase activity#GO:0140938;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;methyltransferase activity#GO:0008168;transcription regulator activity#GO:0140110;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;transcription coactivator activity#GO:0003713;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000008495.1|UniProtKB=W5MPN7 W5MPN7 PTHR10073:SF52 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MISMATCH REPAIR ENDONUCLEASE PMS2 ISOFORM X1 endonuclease activity#GO:0004519;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;mismatch repair#GO:0006298;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001260.1|UniProtKB=W5LZ68 W5LZ68 PTHR24104:SF55 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM71 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;nucleic acid binding#GO:0003676;binding#GO:0005488;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;RNA binding#GO:0003723 post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;post-transcriptional regulation of gene expression#GO:0010608;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000017929.1|UniProtKB=W5NN23 W5NN23 PTHR24366:SF177 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 53 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000010348.1|UniProtKB=W5MWD1 W5MWD1 PTHR11243:SF15 GROWTH FACTOR RECEPTOR-BOUND PROTEIN RAS-ASSOCIATED AND PLECKSTRIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013422.1|UniProtKB=W5N7E1 W5N7E1 PTHR14074:SF16 HELICASE WITH DEATH DOMAIN-RELATED ANTIVIRAL INNATE IMMUNE RESPONSE RECEPTOR RIG-I zinc ion binding#GO:0008270;single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;double-stranded RNA binding#GO:0003725;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;RNA binding#GO:0003723;cation binding#GO:0043169 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002035.1|UniProtKB=W5M1U7 W5M1U7 PTHR31129:SF2 GLYCOPROTEIN HORMONE ALPHA-2 GLYCOPROTEIN HORMONES ALPHA CHAIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;binding#GO:0005488 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000017690.1|UniProtKB=W5NMD6 W5NMD6 PTHR40472:SF8 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 2 LEPOC|Ensembl=ENSLOCG00000009404.1|UniProtKB=W5MSW2 W5MSW2 PTHR21237:SF10 GRPE PROTEIN GRPE PROTEIN HOMOLOG 2, MITOCHONDRIAL molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002624.1|UniProtKB=W5M3X9 W5M3X9 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012146.1|UniProtKB=W5N2U3 W5N2U3 PTHR12553:SF49 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;gene expression#GO:0010467;tRNA 3'-end processing#GO:0042780;mitochondrial RNA 3'-end processing#GO:0000965;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000010245.1|UniProtKB=W5MW07 W5MW07 PTHR11453:SF14 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN 2 active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;chloride transmembrane transporter activity#GO:0015108;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 apical part of cell#GO:0045177;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;apical plasma membrane#GO:0016324;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000005018.1|UniProtKB=W5MCD0 W5MCD0 PTHR48051:SF58 FAMILY NOT NAMED VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8E cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009750.1|UniProtKB=W5MU56 W5MU56 PTHR24317:SF7 PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;diterpenoid metabolic process#GO:0016101;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009808.1|UniProtKB=W5MUB9 W5MUB9 PTHR12392:SF0 LADININ 1 LADININ-1 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016061.1|UniProtKB=W5NGN3 W5NGN3 PTHR24026:SF36 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 1 neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;axon development#GO:0061564;neuron projection development#GO:0031175 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000003447.1|UniProtKB=W5M6T0 W5M6T0 PTHR24208:SF117 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;forebrain development#GO:0030900;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;cellular process#GO:0009987;head development#GO:0060322;nervous system development#GO:0007399;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;animal organ development#GO:0048513 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012705.1|UniProtKB=W5N4S8 W5N4S8 PTHR13170:SF24 O-GLCNACASE PROTEIN O-GLCNACASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;glycoprotein metabolic process#GO:0009100;carbohydrate derivative metabolic process#GO:1901135 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000030.1|UniProtKB=W5LV78 W5LV78 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007674.1|UniProtKB=W5MLS7 W5MLS7 PTHR12112:SF47 BNIP - RELATED EXOPOLYPHOSPHATASE PRUNE1 pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008643.1|UniProtKB=W5MQ67 W5MQ67 PTHR23250:SF16 DYSFERLIN-RELATED TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 1 binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289 cellular component organization#GO:0016043;cellular process#GO:0009987;autophagy#GO:0006914;catabolic process#GO:0009056;macroautophagy#GO:0016236;protein-containing complex disassembly#GO:0032984;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;process utilizing autophagic mechanism#GO:0061919;protein-containing complex organization#GO:0043933 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;autophagosome#GO:0005776;intracellular organelle#GO:0043229;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000016987.1|UniProtKB=W5NK38 W5NK38 PTHR24418:SF44 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FYN non-membrane spanning protein tyrosine kinase activity#GO:0004715;signaling receptor binding#GO:0005102;binding#GO:0005488;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096 regulation of immune response#GO:0050776;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;immune system process#GO:0002376;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of immune response#GO:0050778;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;T cell receptor signaling pathway#GO:0050852;immune response-activating signaling pathway#GO:0002757;cellular developmental process#GO:0048869;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 Integrin signalling pathway#P00034>Fyn#P00942;Cadherin signaling pathway#P00012>Fyn#P00464;Parkinson disease#P00049>Src kinase#P01230;Axon guidance mediated by semaphorins#P00007>Fyn#P00335;Parkinson disease#P00049>Fyn kinase#P01235 LEPOC|Ensembl=ENSLOCG00000007935.1|UniProtKB=W5MMN5 W5MMN5 PTHR45742:SF4 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C6 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;immune system process#GO:0002376;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;extracellular region#GO:0005576 complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000013232.1|UniProtKB=W5N6Q0 W5N6Q0 PTHR12558:SF13 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 27 HOMOLOG enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;mitotic cell cycle phase transition#GO:0044772;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent protein catabolic process#GO:0019941;cell division#GO:0051301;cell cycle#GO:0007049;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;metaphase/anaphase transition of cell cycle#GO:0044784;regulation of chromosome segregation#GO:0051983;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128 nucleus#GO:0005634;cytoplasm#GO:0005737;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014899.1|UniProtKB=W5NCI9 W5NCI9 PTHR23043:SF25 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000005650.1|UniProtKB=W5MEN3 W5MEN3 PTHR13743:SF111 BEIGE/BEACH-RELATED NEUROBEACHIN-LIKE PROTEIN 2 cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;anatomical structure formation involved in morphogenesis#GO:0048646;developmental process#GO:0032502;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;cell morphogenesis#GO:0000902;hemopoiesis#GO:0030097;cell development#GO:0048468;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003568.1|UniProtKB=W5M768 W5M768 PTHR23136:SF11 TAX1-BINDING PROTEIN 3-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 5 LEPOC|Ensembl=ENSLOCG00000009503.1|UniProtKB=W5MTB4 W5MTB4 PTHR45620:SF19 PDF RECEPTOR-LIKE PROTEIN-RELATED CORTICOTROPIN-RELEASING HORMONE RECEPTOR 2 hormone binding#GO:0042562;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089 regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051 axon terminus#GO:0043679;cell junction#GO:0030054;presynapse#GO:0098793;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;neuron projection terminus#GO:0044306;cell projection#GO:0042995;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202 transmembrane signal receptor#PC00197 Cortocotropin releasing factor receptor signaling pathway#P04380>CRHR1#P04451 LEPOC|Ensembl=ENSLOCG00000000881.1|UniProtKB=W5LXX8 W5LXX8 PTHR43675:SF36 ARSENITE METHYLTRANSFERASE ARSENITE METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule metabolic process#GO:0044281;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;carboxylic acid metabolic process#GO:0019752;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;secondary metabolic process#GO:0019748;response to xenobiotic stimulus#GO:0009410;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004150.1|UniProtKB=W5M9A4 W5M9A4 PTHR11848:SF277 TGF-BETA FAMILY TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000016224.1|UniProtKB=W5NHA0 W5NHA0 PTHR46198:SF2 PROTEIN-TYROSINE-PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE R binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016768.1|UniProtKB=W5NJB8 W5NJB8 PTHR10970:SF5 CLUSTERIN CLUSTERIN protein binding#GO:0005515;binding#GO:0005488 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017414.1|UniProtKB=W5NLL0 W5NLL0 PTHR47981:SF9 RAB FAMILY RAS-RELATED PROTEIN RAB-9A pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 vacuole organization#GO:0007033;localization#GO:0051179;cellular localization#GO:0051641;organelle assembly#GO:0070925;vesicle fusion#GO:0006906;cytosolic transport#GO:0016482;endocytosis#GO:0006897;cellular component organization#GO:0016043;endosomal transport#GO:0016197;receptor-mediated endocytosis#GO:0006898;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;lytic vacuole organization#GO:0080171;transport#GO:0006810;phagolysosome assembly#GO:0001845;intracellular transport#GO:0046907;phagocytosis#GO:0006909;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome organization#GO:0007040;cellular component biogenesis#GO:0044085;retrograde transport, endosome to Golgi#GO:0042147;membrane fusion#GO:0061025;organelle organization#GO:0006996 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole#GO:0000323;phagocytic vesicle#GO:0045335;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;vacuole#GO:0005773 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000010041.1|UniProtKB=W5MV70 W5MV70 PTHR42760:SF139 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER D-ARABINITOL 2-DEHYDROGENASE [RIBULOSE-FORMING] oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014023.1|UniProtKB=W5N9H6 W5N9H6 PTHR23159:SF18 CENTROSOMAL PROTEIN 2 CENTROSOMAL PROTEIN OF 135 KDA microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009309.1|UniProtKB=W5MSJ6 W5MSJ6 PTHR16435:SF7 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000012566.1|UniProtKB=W5N4B1 W5N4B1 PTHR24073:SF366 DRAB5-RELATED RAS-RELATED PROTEIN RAB-5C pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 endocytosis#GO:0006897;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000010470.1|UniProtKB=W5MWS2 W5MWS2 PTHR22811:SF223 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 5 ISOFORM X1 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012112.1|UniProtKB=W5N2P2 W5N2P2 PTHR11588:SF88 TUBULIN TUBULIN BETA-6 CHAIN nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001 microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085;tubulin#PC00228 Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780 LEPOC|Ensembl=ENSLOCG00000007882.1|UniProtKB=W5MMG2 W5MMG2 PTHR11863:SF225 STEROL DESATURASE METHYLSTEROL MONOOXYGENASE 1 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000017547.1|UniProtKB=W5NLZ3 W5NLZ3 PTHR12307:SF13 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3B protein phosphatase binding#GO:0019903;carbohydrate binding#GO:0030246;protein binding#GO:0005515;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488;polysaccharide binding#GO:0030247 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000007815.1|UniProtKB=W5MM76 W5MM76 PTHR11309:SF149 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 2-LIKE transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;non-canonical Wnt signaling pathway#GO:0035567;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007097.1|UniProtKB=W5MJN1 W5MJN1 PTHR45701:SF1 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 1 syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;binding#GO:0005488 membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;vesicle fusion#GO:0006906;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;localization#GO:0051179 cytoplasm#GO:0005737;plasma membrane#GO:0005886;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Synaptic vesicle trafficking#P05734>Synaptobrevin#P05779;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005 LEPOC|Ensembl=ENSLOCG00000001263.1|UniProtKB=W5LZ75 W5LZ75 MMP7 PTHR10201:SF165 MATRIX METALLOPROTEINASE COLLAGENASE 3 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Plasminogen activating cascade#P00050>pro-MMP-13#P01254;Plasminogen activating cascade#P00050>MMP-13#P01250 LEPOC|Ensembl=ENSLOCG00000016414.1|UniProtKB=W5NI13 W5NI13 PTHR23032:SF13 BRO1 DOMAIN-CONTAINING PROTEIN BROX BRO1 DOMAIN-CONTAINING PROTEIN BROX LEPOC|Ensembl=ENSLOCG00000007987.1|UniProtKB=W5MMT9 W5MMT9 PTHR28663:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 173 CILIA- AND FLAGELLA- ASSOCIATED PROTEIN 210 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoplasmic microtubule#GO:0005881;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000000992.1|UniProtKB=W5LYC6 W5LYC6 PTHR14553:SF1 UNCHARACTERIZED PROTEIN C1ORF50 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 50 LEPOC|Ensembl=ENSLOCG00000016220.1|UniProtKB=W5NH91 W5NH91 PTHR19346:SF5 SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN SOLUTE CARRIER FAMILY 35 MEMBER F3 ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000012833.1|UniProtKB=W5N583 W5N583 PTHR12128:SF74 DIHYDRODIPICOLINATE SYNTHASE 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;aldehyde catabolic process#GO:0046185;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;glyoxylate metabolic process#GO:0046487;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000005497.1|UniProtKB=W5ME24 W5ME24 PTHR14952:SF12 ROPPORIN-1-LIKE PROTEIN ROPPORIN-1B spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;spermatid development#GO:0007286;cilium-dependent cell motility#GO:0060285;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;sperm motility#GO:0097722;cell differentiation#GO:0030154;cell motility#GO:0048870;gamete generation#GO:0007276;microtubule-based movement#GO:0007018;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;cell maturation#GO:0048469;cellular developmental process#GO:0048869;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;developmental maturation#GO:0021700;male gamete generation#GO:0048232;sperm capacitation#GO:0048240 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514 LEPOC|Ensembl=ENSLOCG00000014713.1|UniProtKB=W5NBV5 W5NBV5 PTHR22691:SF1 YEAST SPT2-RELATED CENTROSOMAL PROTEIN CCDC61 cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006743.1|UniProtKB=W5MID9 W5MID9 PTHR10807:SF37 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 12 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;dephosphorylation#GO:0016311;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000002174.1|UniProtKB=W5M2D3 W5M2D3 PTHR23512:SF5 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 LYSOSOMAL DIPEPTIDE TRANSPORTER MFSD1 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000006204.1|UniProtKB=W5MGI6 W5MGI6 PTHR13505:SF7 TRANSMEMBRANE PROTEIN 208 TRANSMEMBRANE PROTEIN 208 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 LEPOC|Ensembl=ENSLOCG00000001933.1|UniProtKB=W5M1H6 W5M1H6 PTHR46337:SF1 RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;cellular component organization or biogenesis#GO:0071840;mitochondrial ribosome assembly#GO:0061668;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular process#GO:0009987;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;ribonucleoprotein complex biogenesis#GO:0022613;mitochondrion organization#GO:0007005 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000014302.1|UniProtKB=W5NAF0 W5NAF0 PTHR13710:SF163 DNA HELICASE RECQ FAMILY MEMBER RECQ-LIKE DNA HELICASE BLM catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;telomere organization#GO:0032200 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA helicase#PC00011 LEPOC|Ensembl=ENSLOCG00000007612.1|UniProtKB=W5MLH6 W5MLH6 PTHR19336:SF11 UNCHARACTERIZED DUF1167 CENTROSOMAL PROTEIN OF 57 KDA cytoskeletal protein binding#GO:0008092;cytoskeletal adaptor activity#GO:0008093;tubulin binding#GO:0015631;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;microtubule binding#GO:0008017;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;organelle organization#GO:0006996;attachment of spindle microtubules to kinetochore#GO:0008608;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876 LEPOC|Ensembl=ENSLOCG00000013123.1|UniProtKB=W5N6B6 W5N6B6 PTHR11102:SF147 SEL-1-LIKE PROTEIN PROTEIN SEL-1 HOMOLOG 1 cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016938.1|UniProtKB=W5NJX8 W5NJX8 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 small molecule catabolic process#GO:0044282;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000009415.1|UniProtKB=W5MSY6 W5MSY6 PTHR11141:SF7 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23A enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641 cytoplasm#GO:0005737;vesicle coat#GO:0030120;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002691.1|UniProtKB=W5M452 W5M452 PTHR45828:SF54 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELER DOMAIN-CONTAINING PROTEIN PRECURSOR cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000009884.1|UniProtKB=W5MUM0 W5MUM0 PTHR47391:SF1 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 LIKE 1 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 LIKE 1 LEPOC|Ensembl=ENSLOCG00000008431.1|UniProtKB=W5MPG4 W5MPG4 PTHR24223:SF196 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 5 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000016816.1|UniProtKB=W5NJH3 W5NJH3 PTHR13906:SF7 PORCUPINE MEMBRANE-BOUND GLYCEROPHOSPHOLIPID O-ACYLTRANSFERASE 2 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 lipid modification#GO:0030258;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phosphatidylcholine metabolic process#GO:0046470;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000013873.1|UniProtKB=W5N903 W5N903 PTHR15995:SF1 PROTEIN ZWILCH HOMOLOG PROTEIN ZWILCH HOMOLOG regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;protein localization to kinetochore#GO:0034501;macromolecule localization#GO:0033036;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;intracellular protein localization#GO:0008104;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;localization#GO:0051179;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of cell cycle#GO:0045786;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;negative regulation of chromosome segregation#GO:0051985;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816 condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002179.1|UniProtKB=W5M2E5 W5M2E5 PTHR10628:SF23 SIALIDASE SIALIDASE-3 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;carbohydrate catabolic process#GO:0016052;ceramide metabolic process#GO:0006672;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;oligosaccharide metabolic process#GO:0009311 intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004314.1|UniProtKB=W5M9U6 W5M9U6 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000227.1|UniProtKB=W5LVV2 W5LVV2 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000004088.1|UniProtKB=W5M927 W5M927 PTHR23281:SF20 MERLIN/MOESIN/EZRIN/RADIXIN MERLIN actin binding#GO:0003779;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;cell adhesion molecule binding#GO:0050839;integrin binding#GO:0005178 regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of neurogenesis#GO:0050767;regulation of cell population proliferation#GO:0042127;regulation of nervous system development#GO:0051960;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;regulation of cell development#GO:0060284;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of hippo signaling#GO:0035330;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of multicellular organismal development#GO:2000026;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of multicellular organismal process#GO:0051239;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of anatomical structure morphogenesis#GO:0022603;regulation of localization#GO:0032879;regulation of transport#GO:0051049 actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;filopodium#GO:0030175;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000010266.1|UniProtKB=W5MW14 W5MW14 PTHR11743:SF13 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL NON-SELECTIVE VOLTAGE-GATED ION CHANNEL VDAC1 gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic anion channel activity#GO:0008308 mitochondrial transport#GO:0006839;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;cell periphery#GO:0071944;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000006484.1|UniProtKB=W5MHH2 W5MHH2 PTHR24123:SF92 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT DOMAIN 50-LIKE localization within membrane#GO:0051668;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001506.1|UniProtKB=W5M049 W5M049 PTHR11884:SF1 SELECTIN LIGAND RELATED GOLGI APPARATUS PROTEIN 1 growth factor binding#GO:0019838;protein binding#GO:0005515;fibroblast growth factor binding#GO:0017134;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000006247.1|UniProtKB=W5MGN7 W5MGN7 PTHR24089:SF765 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SLC25A23 ISOFORM X1 phosphate transmembrane transporter activity#GO:0005315;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;purine nucleotide transmembrane transporter activity#GO:0015216;active transmembrane transporter activity#GO:0022804 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 LEPOC|Ensembl=ENSLOCG00000017851.1|UniProtKB=W5NMU5 W5NMU5 PTHR10903:SF206 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000013746.1|UniProtKB=W5N8J3 W5N8J3 PTHR24237:SF14 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 34-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012379.1|UniProtKB=W5N3N5 W5N3N5 PTHR12659:SF4 RHO-TYPE GTPASE ACTIVATING PROTEIN RHO-GAP DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of cell communication#GO:0010646;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;actin filament-based process#GO:0030029;regulation of signaling#GO:0023051 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000012595.1|UniProtKB=W5N4E9 W5N4E9 PTHR45625:SF18 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 1 catalytic activity#GO:0003824;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008372.1|UniProtKB=W5MP65 W5MP65 PTHR10585:SF37 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR 2 signal sequence receptor activity#GO:0005048 intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;macromolecule localization#GO:0033036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007670.1|UniProtKB=W5MLP8 W5MLP8 PTHR24086:SF49 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;hormone-mediated signaling pathway#GO:0009755;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to chemical stimulus#GO:0070887 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000017755.1|UniProtKB=W5NMK0 W5NMK0 PTHR24229:SF6 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2 molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;binding#GO:0005488;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to steroid hormone#GO:0048545;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;biological regulation#GO:0065007;response to estradiol#GO:0032355;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;cellular response to steroid hormone stimulus#GO:0071383 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000013720.1|UniProtKB=W5N8F7 W5N8F7 PTHR48051:SF48 FAMILY NOT NAMED MULTIFUNCTIONAL ROCO FAMILY SIGNALING REGULATOR 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014630.1|UniProtKB=W5NBJ8 W5NBJ8 PTHR23351:SF3 FOS TRANSCRIPTION FACTOR-RELATED PROTEIN FOSB sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>Fosb#G06666;Gonadotropin-releasing hormone receptor pathway#P06664>Fosb#G06878;Gonadotropin-releasing hormone receptor pathway#P06664>FOS#P06709 LEPOC|Ensembl=ENSLOCG00000003194.1|UniProtKB=W5M5W7 W5M5W7 PTHR12801:SF152 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED ZGC:152968 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640 nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 exoribonuclease#PC00099;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001601.1|UniProtKB=W5M0D4 W5M0D4 PTHR46677:SF1 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1 localization#GO:0051179;intracellular protein localization#GO:0008104;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;protein localization to organelle#GO:0033365;response to stimulus#GO:0050896;response to stress#GO:0006950;macromolecule localization#GO:0033036;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;site of double-strand break#GO:0035861;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000014840.1|UniProtKB=W5NCB5 W5NCB5 PTHR10390:SF65 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013953.1|UniProtKB=W5N994 W5N994 PTHR47130:SF1 SI:DKEY-19B23.11-RELATED ZP DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015871.1|UniProtKB=W5NFY8 W5NFY8 PTHR11405:SF5 CARBAMOYLTRANSFERASE FAMILY MEMBER MULTIFUNCTIONAL PROTEIN CAD hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;ligase activity#GO:0016874;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;ligase activity, forming carbon-nitrogen bonds#GO:0016879;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;ligase#PC00142 De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925;Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845 LEPOC|Ensembl=ENSLOCG00000007166.1|UniProtKB=W5MK05 W5MK05 PTHR24023:SF1130 COLLAGEN ALPHA COLLAGEN, TYPE V, ALPHA 3A ISOFORM X1-RELATED extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000000803.1|UniProtKB=W5LXS1 W5LXS1 PTHR13738:SF12 TROPONIN I TROPONIN 1-RELATED protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 blood circulation#GO:0008015;multicellular organismal process#GO:0032501;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;muscle system process#GO:0003012;heart process#GO:0003015;heart contraction#GO:0060047;system process#GO:0003008;circulatory system process#GO:0003013;muscle contraction#GO:0006936;cardiac muscle contraction#GO:0060048;neuromuscular process#GO:0050905;nervous system process#GO:0050877 cytoskeleton#GO:0005856;sarcomere#GO:0030017;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003318.1|UniProtKB=W5M6C1 W5M6C1 PTHR11748:SF111 D-LACTATE DEHYDROGENASE D-LACTATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014661.1|UniProtKB=W5NBN4 W5NBN4 PTHR10501:SF63 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;U1 snRNP#GO:0005685;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 mRNA splicing#P00058>U1#P01479 LEPOC|Ensembl=ENSLOCG00000011380.1|UniProtKB=W5N034 W5N034 PTHR10877:SF47 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2-LIKE PROTEIN 2 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 response to mechanical stimulus#GO:0009612;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;detection of mechanical stimulus#GO:0050982;response to external stimulus#GO:0009605;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000016404.1|UniProtKB=W5NHZ9 W5NHZ9 PTHR11036:SF36 SEMAPHORIN SEMAPHORIN-3D receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;mesenchyme development#GO:0060485;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;cellular developmental process#GO:0048869;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;axon guidance#GO:0007411;stem cell differentiation#GO:0048863;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;tissue development#GO:0009888;cell migration#GO:0016477;neural crest cell development#GO:0014032;chemotaxis#GO:0006935;stem cell development#GO:0048864;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;mesenchymal cell differentiation#GO:0048762;neuron differentiation#GO:0030182;neural crest cell differentiation#GO:0014033;cell projection morphogenesis#GO:0048858;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neural crest cell migration#GO:0001755;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000006961.1|UniProtKB=W5MJ57 W5MJ57 PTHR12219:SF8 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL cellular respiration#GO:0045333;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 mitochondrion#GO:0005739;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004833.1|UniProtKB=W5MBP4 W5MBP4 PTHR24014:SF6 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049 gene expression#GO:0010467;tRNA 3'-end processing#GO:0042780;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;mitochondrial RNA metabolic process#GO:0000959;mitochondrial RNA modification#GO:1900864;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018100.1|UniProtKB=W5NNJ2 W5NNJ2 PTHR24226:SF2 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 G PROTEIN-COUPLED ESTROGEN RECEPTOR 1 signaling receptor activity#GO:0038023;steroid binding#GO:0005496;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;lipid binding#GO:0008289;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;intracellular receptor signaling pathway#GO:0030522;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to steroid hormone#GO:0048545;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;nuclear receptor-mediated signaling pathway#GO:0141193;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;estrogen receptor signaling pathway#GO:0030520;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cell cycle#GO:0051726;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;hormone-mediated signaling pathway#GO:0009755;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;response to estradiol#GO:0032355;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;regulation of ERK1 and ERK2 cascade#GO:0070372;response to chemical#GO:0042221;regulation of MAPK cascade#GO:0043408;cellular response to steroid hormone stimulus#GO:0071383 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007376.1|UniProtKB=W5MKR8 W5MKR8 PTHR45627:SF9 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 7 cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cyclic nucleotide biosynthetic process#GO:0009190;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 adenylate cyclase#PC00043 5HT1 type receptor mediated signaling pathway#P04373>AC#P04406;Beta3 adrenergic receptor signaling pathway#P04379>AC#P04450;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Dopamine receptor mediated signaling pathway#P05912>AC#P05947;Opioid prodynorphin pathway#P05916>AC#P06001;Beta1 adrenergic receptor signaling pathway#P04377>AC#P04439;Opioid proenkephalin pathway#P05915>AC#P05993;Beta2 adrenergic receptor signaling pathway#P04378>AC#P04446;5HT4 type receptor mediated signaling pathway#P04376>AC#P04429;Histamine H2 receptor mediated signaling pathway#P04386>AC#P04492;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Enkephalin release#P05913>AC#P05978;Opioid proopiomelanocortin pathway#P05917>AC#P06011 LEPOC|Ensembl=ENSLOCG00000003897.1|UniProtKB=W5M8E3 W5M8E3 METTL1 PTHR23417:SF16 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987 methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010671.1|UniProtKB=W5MXG2 W5MXG2 PTHR23192:SF7 OLFACTOMEDIN-RELATED OLFACTOMEDIN-4 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000007256.1|UniProtKB=W5MK89 W5MK89 PTHR13697:SF59 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, MUSCLE TYPE transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200;carbohydrate derivative binding#GO:0097367;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;nicotinamide nucleotide metabolic process#GO:0046496;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule catabolic process#GO:0044282 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 carbohydrate kinase#PC00065;kinase#PC00137;transferase#PC00220 Glycolysis#P00024>Phosphofructokinase-1#P00672 LEPOC|Ensembl=ENSLOCG00000003158.1|UniProtKB=W5M5R6 W5M5R6 PTHR10378:SF8 LIM DOMAIN-BINDING PROTEIN LIM DOMAIN-BINDING PROTEIN 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000009387.1|UniProtKB=W5MSU3 W5MSU3 PTHR15261:SF4 THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING PROTEIN cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015686.1|UniProtKB=W5NFA2 W5NFA2 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015572.1|UniProtKB=W5NEW6 W5NEW6 PTHR10131:SF83 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;signal transduction#GO:0007165;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010473.1|UniProtKB=W5MWU7 W5MWU7 PTHR45859:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT BETA enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;guanyl-nucleotide exchange factor activity#GO:0005085;translation factor activity#GO:0180051 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000015279.1|UniProtKB=W5NDU2 W5NDU2 PTHR43108:SF9 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-ACETYLGLUCOSAMINE-6-SULFATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;glycoprotein metabolic process#GO:0009100;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016884.1|UniProtKB=W5NJR2 W5NJR2 PTHR10063:SF2 TUBERIN RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-2 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000004572.1|UniProtKB=W5MAR2 W5MAR2 PTHR21660:SF1 THIOESTERASE SUPERFAMILY MEMBER-RELATED ACYL-COENZYME A THIOESTERASE 13 hydrolase activity#GO:0016787;deacylase activity#GO:0160215;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 esterase#PC00097;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002094.1|UniProtKB=W5M239 W5M239 PTHR47977:SF73 RAS-RELATED PROTEIN RAB RAS AND EF-HAND DOMAIN-CONTAINING PROTEIN nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;GDP binding#GO:0019003;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cytosol#GO:0005829;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000007673.1|UniProtKB=W5MLQ9 W5MLQ9 PTHR45678:SF7 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED ELECTROGENIC ASPARTATE_GLUTAMATE ANTIPORTER SLC25A12, MITOCHONDRIAL carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;acidic amino acid transmembrane transporter activity#GO:0015172;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310 establishment of localization#GO:0051234;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;dicarboxylic acid transport#GO:0006835;nucleobase-containing compound metabolic process#GO:0006139;nitrogen compound transport#GO:0071705;NAD+ metabolic process#GO:0019674;L-amino acid transport#GO:0015807;aspartate transmembrane transport#GO:0015810;organophosphate metabolic process#GO:0019637;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;L-glutamate import#GO:0051938;pyridine-containing compound metabolic process#GO:0072524;carboxylic acid transmembrane transport#GO:1905039;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;L-alpha-amino acid transmembrane transport#GO:1902475;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;L-glutamate transmembrane transport#GO:0015813;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;transmembrane transport#GO:0055085;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017779.1|UniProtKB=W5NMM4 W5NMM4 PTHR12365:SF8 SPROUTY PROTEIN SPROUTY HOMOLOG 2 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;kinase inhibitor activity#GO:0019210;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of intracellular signal transduction#GO:1902532;regulation of Ras protein signal transduction#GO:0046578;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;biological regulation#GO:0065007;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of signal transduction#GO:0009968;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>SPRY#G01511;EGF receptor signaling pathway#P00018>Spry#P00541;FGF signaling pathway#P00021>Spry#P00626 LEPOC|Ensembl=ENSLOCG00000005125.1|UniProtKB=W5MCR7 W5MCR7 PTHR45706:SF5 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 3 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;cytoplasmic side of membrane#GO:0098562 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000017694.1|UniProtKB=W5NME0 W5NME0 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008092.1|UniProtKB=W5MN66 W5MN66 PTHR28653:SF1 FAMILY NOT NAMED ATPASE SWSAP1 LEPOC|Ensembl=ENSLOCG00000016803.1|UniProtKB=W5NJG3 W5NJG3 PTHR14768:SF3 UPF0338 PROTEIN SYNAPSE DIFFERENTIATION-INDUCING GENE PROTEIN 1 vesicle-mediated transport in synapse#GO:0099003;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;positive regulation of cellular component biogenesis#GO:0044089;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;positive regulation of cellular component organization#GO:0051130;regulation of synapse organization#GO:0050807;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of cellular component biogenesis#GO:0044087;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;positive regulation of developmental process#GO:0051094;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;positive regulation of synapse assembly#GO:0051965;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;vesicle localization#GO:0051648;biological regulation#GO:0065007;regulation of synapse assembly#GO:0051963;regulation of cell junction assembly#GO:1901888;organelle localization#GO:0051640;localization#GO:0051179;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794 intracellular vesicle#GO:0097708;postsynapse#GO:0098794;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;synaptic membrane#GO:0097060;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;asymmetric synapse#GO:0032279;postsynaptic density#GO:0014069;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;postsynaptic density membrane#GO:0098839;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;transport vesicle#GO:0030133;neuron to neuron synapse#GO:0098984;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000016493.1|UniProtKB=W5NIB4 W5NIB4 PTHR45813:SF2 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F3 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006555.1|UniProtKB=W5MHR1 W5MHR1 PTHR45832:SF10 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000016239.1|UniProtKB=W5NHB2 W5NHB2 PTHR12232:SF14 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006727.1|UniProtKB=W5MIB9 W5MIB9 PTHR45762:SF21 ZINC FINGER RNA-BINDING PROTEIN ZINC FINGER RNA-BINDING PROTEIN single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018172.1|UniProtKB=W5NNR4 W5NNR4 PTHR12887:SF13 NANOS PROTEIN NANOS HOMOLOG 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;cell differentiation#GO:0030154;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of translation#GO:0017148;oogenesis#GO:0048477;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017170.1|UniProtKB=W5NKR4 W5NKR4 PTHR10827:SF91 RETICULOCALBIN RETICULOCALBIN 3, EF-HAND CALCIUM BINDING DOMAIN metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000002790.1|UniProtKB=W5M4H9 W5M4H9 PTHR46596:SF1 SORTING NEXIN-4 SORTING NEXIN-4 phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phosphatidylinositol-3-phosphate binding#GO:0032266;binding#GO:0005488;phospholipid binding#GO:0005543 regulation of cellular component biogenesis#GO:0044087;positive regulation of macroautophagy#GO:0016239;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;protein transport#GO:0015031;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;localization#GO:0051179;positive regulation of cellular component organization#GO:0051130;regulation of autophagosome assembly#GO:2000785;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of organelle assembly#GO:1902115;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;positive regulation of autophagy#GO:0010508;macromolecule localization#GO:0033036;regulation of catabolic process#GO:0009894;intracellular protein localization#GO:0008104;regulation of macroautophagy#GO:0016241;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005959.1|UniProtKB=W5MFQ0 W5MFQ0 PTHR22878:SF63 DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED DYNEIN HEAVY CHAIN 10, AXONEMAL Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000010780.1|UniProtKB=W5MXV0 W5MXV0 PTHR10331:SF27 T COMPLEX PROTEIN 10 CENTROSOMAL P4.1-ASSOCIATED PROTEIN protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cilium assembly#GO:0060271;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell projection organization#GO:0030030;organelle assembly#GO:0070925;centriole replication#GO:0007099;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782 cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008319.1|UniProtKB=W5MNZ9 W5MNZ9 PTHR13723:SF197 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 19 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000017374.1|UniProtKB=W5NLH0 W5NLH0 PTHR24233:SF8 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 87 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016078.1|UniProtKB=W5NGQ1 W5NGQ1 PTHR15840:SF10 CGI-121 FAMILY MEMBER EKC_KEOPS COMPLEX SUBUNIT TPRKB metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000004523.1|UniProtKB=W5MAK0 W5MAK0 PTHR11830:SF17 40S RIBOSOMAL PROTEIN S3A UBIQUITINYL HYDROLASE 1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;structural constituent of ribosome#GO:0003735;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000005393.1|UniProtKB=W5MDP3 W5MDP3 PTHR46811:SF1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000011115.1|UniProtKB=W5MZ47 W5MZ47 PTHR24100:SF164 BUTYROPHILIN V-SET DOMAIN-CONTAINING T-CELL ACTIVATION INHIBITOR 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008235.1|UniProtKB=W5MNN9 W5MNN9 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune system process#GO:0002376;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;immune response#GO:0006955;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000009939.1|UniProtKB=W5MUW3 W5MUW3 PTHR23255:SF70 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-2B molecular transducer activity#GO:0060089;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;signaling receptor activity#GO:0038023;activin binding#GO:0048185;kinase activity#GO:0016301;transferase activity#GO:0016740 multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;activin receptor signaling pathway#GO:0032924;pattern specification process#GO:0007389 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;signaling receptor complex#GO:0043235;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII/IIB#P06780;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277 LEPOC|Ensembl=ENSLOCG00000015641.1|UniProtKB=W5NF45 W5NF45 PTHR12067:SF5 PODOCALYXIN PODOCALYXIN regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;negative regulation of cell adhesion#GO:0007162;negative regulation of cell-cell adhesion#GO:0022408;cell migration#GO:0016477;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of cell projection assembly#GO:0060491;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of cell adhesion#GO:0045785;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cell-cell adhesion#GO:0022407;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087 membraneless organelle#GO:0043228;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cell projection membrane#GO:0031253;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;microvillus#GO:0005902;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015523.1|UniProtKB=W5NEP7 W5NEP7 PTHR23064:SF78 TROPONIN TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cytoskeletal protein binding#GO:0008092 muscle system process#GO:0003012;heart process#GO:0003015;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;striated muscle contraction#GO:0006941;skeletal muscle contraction#GO:0003009;circulatory system process#GO:0003013;cardiac muscle contraction#GO:0060048;neuromuscular process#GO:0050905;muscle contraction#GO:0006936;nervous system process#GO:0050877;system process#GO:0003008;heart contraction#GO:0060047 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;contractile muscle fiber#GO:0043292;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sarcomere#GO:0030017 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000010416.1|UniProtKB=W5MWM8 W5MWM8 SUCLA2 PTHR11815:SF1 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 cellular respiration#GO:0045333;aerobic respiration#GO:0009060;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound metabolic process#GO:0006790;tricarboxylic acid cycle#GO:0006099;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 mitochondrion#GO:0005739;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000014223.1|UniProtKB=W5NA57 W5NA57 PTHR14768:SF2 UPF0338 PROTEIN TRANSMEMBRANE PROTEIN 91 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006983.1|UniProtKB=W5MJ93 W5MJ93 PTHR45829:SF5 MITOCHONDRIAL CARRIER PROTEIN RIM2 SOLUTE CARRIER FAMILY 25 MEMBER 33 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000011803.1|UniProtKB=W5N1K9 W5N1K9 PTHR10825:SF21 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB COMPLEX PROTEIN BMI-1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000009354.1|UniProtKB=W5MSS6 W5MSS6 PTHR11771:SF5 LIPOXYGENASE POLYUNSATURATED FATTY ACID 5-LIPOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;arachidonate metabolic process#GO:0019369;lipid oxidation#GO:0034440;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009968.1|UniProtKB=W5MUZ0 W5MUZ0 PTHR24131:SF5 APOPTOSIS-STIMULATING OF P53 PROTEIN APOPTOSIS-STIMULATING OF P53 PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;apoptotic signaling pathway#GO:0097190;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;cell death#GO:0008219;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;intracellular signal transduction#GO:0035556;signal transduction by p53 class mediator#GO:0072331 intracellular organelle#GO:0043229;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;nucleus#GO:0005634;cell-cell junction#GO:0005911;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005507.1|UniProtKB=W5ME35 W5ME35 PTHR12951:SF5 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG A binding#GO:0005488;lipid binding#GO:0008289 cell division#GO:0051301;cell cycle#GO:0007049;negative regulation of cellular component organization#GO:0051129;negative regulation of transport#GO:0051051;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;localization#GO:0051179;macromolecule localization#GO:0033036;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of receptor-mediated endocytosis#GO:0048259;cytokinesis#GO:0000910;cilium organization#GO:0044782;protein transport#GO:0015031;cytoskeleton-dependent cytokinesis#GO:0061640;cell projection assembly#GO:0030031;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular component organization or biogenesis#GO:0071840 spindle pole#GO:0000922;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014334.1|UniProtKB=W5NAJ0 W5NAJ0 PTHR11848:SF22 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 15 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000009001.1|UniProtKB=W5MRF3 W5MRF3 PTHR18934:SF213 ATP-DEPENDENT RNA HELICASE 3'-5' RNA HELICASE YTHDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001019.1|UniProtKB=W5LYD6 W5LYD6 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000322.1|UniProtKB=W5LW41 W5LW41 PTHR48071:SF41 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010633.1|UniProtKB=W5MXA7 W5MXA7 PTHR31475:SF5 UPF0462 PROTEIN UPF0462 PROTEIN C4ORF33 HOMOLOG LEPOC|Ensembl=ENSLOCG00000003742.1|UniProtKB=W5M7V0 W5M7V0 PTHR13103:SF2 SCHWANNOMIN INTERACTING PROTEIN 1 IQCJ-SCHIP1 READTHROUGH TRANSCRIPT PROTEIN-RELATED positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010063.1|UniProtKB=W5MV98 W5MV98 PTHR15228:SF36 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 24 ISOFORM X1 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 regulation of small GTPase mediated signal transduction#GO:0051056;morphogenesis of an epithelium#GO:0002009;negative regulation of signal transduction#GO:0009968;response to stress#GO:0006950;cellular process#GO:0009987;negative regulation of intracellular signal transduction#GO:1902532;wound healing#GO:0042060;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;epithelium development#GO:0060429;negative regulation of response to stimulus#GO:0048585;cell migration#GO:0016477;tissue development#GO:0009888;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to wounding#GO:0009611;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;regulation of cell projection assembly#GO:0060491;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cell communication#GO:0010646;negative regulation of cellular component organization#GO:0051129 focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000016732.1|UniProtKB=W5NJ68 W5NJ68 PTHR10233:SF14 TRANSLATION INITIATION FACTOR EIF-2B TRANSLATION INITIATION FACTOR EIF2B SUBUNIT DELTA translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000002220.1|UniProtKB=W5M2I2 W5M2I2 PTHR10012:SF0 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;phosphatase activator activity#GO:0019211;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047;protein phosphatase regulator activity#GO:0019888;cis-trans isomerase activity#GO:0016859;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase activator#PC00182 LEPOC|Ensembl=ENSLOCG00000007194.1|UniProtKB=W5MJZ7 W5MJZ7 PTHR12443:SF9 TRANSLOCATION PROTEIN SEC62 TRANSLOCATION PROTEIN SEC62 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transmembrane protein transporter activity#GO:0008320 localization within membrane#GO:0051668;protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000003416.1|UniProtKB=W5M6P3 W5M6P3 PTHR13720:SF24 WD-40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 90 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000018086.1|UniProtKB=W5NNH8 W5NNH8 PTHR23022:SF136 TRANSPOSABLE ELEMENT-RELATED SI:DKEY-77F5.3 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000012195.1|UniProtKB=W5N2Y9 W5N2Y9 PTHR15528:SF12 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-BETA transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;multicellular organismal-level homeostasis#GO:0048871;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;homeostatic process#GO:0042592;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000006849.1|UniProtKB=W5MIS0 W5MIS0 PTHR47142:SF1 BETA-CATENIN-INTERACTING PROTEIN 1 BETA-CATENIN-INTERACTING PROTEIN 1 binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 regulation of cellular process#GO:0050794;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000014013.1|UniProtKB=W5N9G3 W5N9G3 PTHR12149:SF8 FRUCTOSAMINE 3 KINASE-RELATED PROTEIN PROTEIN-RIBULOSAMINE 3-KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;protein repair#GO:0030091;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001296.1|UniProtKB=W5LZB1 W5LZB1 PTHR10201:SF316 MATRIX METALLOPROTEINASE MATRIX METALLOPEPTIDASE 30 PRECURSOR-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000012618.1|UniProtKB=W5N4H6 W5N4H6 PTHR15670:SF4 RHO GTPASE ACTIVATING PROTEIN 11A INACTIVE RHO GTPASE-ACTIVATING PROTEIN 11B-RELATED enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000004922.1|UniProtKB=W5MC11 W5MC11 PTHR11006:SF125 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;histone modifying activity#GO:0140993 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006853.1|UniProtKB=W5MIV1 W5MIV1 PTHR23172:SF4 AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED AUXILIN binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515 synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;cellular component disassembly#GO:0022411;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;protein-containing complex disassembly#GO:0032984 postsynapse#GO:0098794;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004298.1|UniProtKB=W5M9S6 W5M9S6 PTHR11081:SF49 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE 1 HOMOLOG-RELATED catalytic activity, acting on DNA#GO:0140097;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;DNA endonuclease activity#GO:0004520;metal ion binding#GO:0046872;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;exonuclease activity#GO:0004527;binding#GO:0005488;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;hydrolase activity#GO:0016787;cation binding#GO:0043169;magnesium ion binding#GO:0000287;ion binding#GO:0043167;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 exodeoxyribonuclease#PC00098;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010330.1|UniProtKB=W5MWA7 W5MWA7 PTHR11532:SF63 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE Z catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009807.1|UniProtKB=W5MUD7 W5MUD7 PTHR18966:SF157 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1 gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;molecular transducer activity#GO:0060089;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794 signaling receptor complex#GO:0043235;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;dendrite#GO:0030425;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;neuron projection#GO:0043005;protein-containing complex#GO:0032991;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynapse#GO:0098794;dendritic spine#GO:0043197;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuron spine#GO:0044309 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 LEPOC|Ensembl=ENSLOCG00000010017.1|UniProtKB=W5MV57 W5MV57 PTHR45799:SF5 RETICULON-LIKE PROTEIN RETICULON-1 endoplasmic reticulum tubular network organization#GO:0071786;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 LEPOC|Ensembl=ENSLOCG00000012383.1|UniProtKB=W5N3P0 W5N3P0 PTHR43735:SF27 APOPTOSIS-INDUCING FACTOR 1 FERROPTOSIS SUPPRESSOR PROTEIN 1 heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;electron transfer activity#GO:0009055;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168 positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;biological regulation#GO:0065007;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;organelle organization#GO:0006996;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 p53 pathway#P00059>NOXA#G01572 LEPOC|Ensembl=ENSLOCG00000001418.1|UniProtKB=W5LZQ8 W5LZQ8 PTHR47312:SF1 MELANOMA-DERIVED GROWTH REGULATORY PROTEIN MELANOMA-DERIVED GROWTH REGULATORY PROTEIN cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000008298.1|UniProtKB=W5MNW9 W5MNW9 PTHR21245:SF3 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 46-RELATED mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008384.1|UniProtKB=W5MP81 W5MP81 PTHR45792:SF2 DIACYLGLYCEROL LIPASE HOMOLOG-RELATED DIACYLGLYCEROL LIPASE-BETA hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;catalytic activity#GO:0003824;triacylglycerol lipase activity#GO:0004806;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;catabolic process#GO:0009056;anatomical structure development#GO:0048856;system development#GO:0048731;multicellular organismal process#GO:0032501;acylglycerol metabolic process#GO:0006639;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;developmental process#GO:0032502;neutral lipid catabolic process#GO:0046461;cellular developmental process#GO:0048869;neutral lipid metabolic process#GO:0006638;neurogenesis#GO:0022008;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;arachidonate metabolic process#GO:0019369;glycerolipid metabolic process#GO:0046486;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;olefinic compound metabolic process#GO:0120254;glycerolipid catabolic process#GO:0046503;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid catabolic process#GO:0016042;icosanoid metabolic process#GO:0006690;nervous system development#GO:0007399;metabolic process#GO:0008152;unsaturated fatty acid metabolic process#GO:0033559;multicellular organism development#GO:0007275;acylglycerol catabolic process#GO:0046464 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008310.1|UniProtKB=W5MNY8 W5MNY8 PTHR15071:SF29 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-DEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR protein-containing complex binding#GO:0044877;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;protein localization to vacuole#GO:0072665;lysosomal transport#GO:0007041;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;protein localization to lysosome#GO:0061462;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;intracellular protein transport#GO:0006886;transport#GO:0006810;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endomembrane system#GO:0012505;late endosome#GO:0005770;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012523.1|UniProtKB=W5N462 W5N462 PTHR46778:SF1 CYCLIN-DEPENDENT KINASE INHIBITOR 1-RELATED CYCLIN-DEPENDENT KINASE INHIBITOR 1 kinase inhibitor activity#GO:0019210;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;regulation of G1/S transition of mitotic cell cycle#GO:2000045;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle phase transition#GO:1901987;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;DNA damage response#GO:0006974;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;response to stress#GO:0006950;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987 protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase inhibitor#PC00139 Interleukin signaling pathway#P00036>p21CIP1#P00993;p53 pathway feedback loops 2#P04398>P21#G04712;p53 pathway#P00059>P21#P04631;p53 pathway#P00059>p21#G01580;p53 pathway feedback loops 2#P04398>p21#P04667 LEPOC|Ensembl=ENSLOCG00000016246.1|UniProtKB=W5NHC3 W5NHC3 PTHR24073:SF1235 DRAB5-RELATED RAS-RELATED PROTEIN RAB-21 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000005358.1|UniProtKB=W5MDJ5 W5MDJ5 PTHR23427:SF1 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 4 cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009929.1|UniProtKB=W5MUT2 W5MUT2 PTHR13598:SF5 AT07567P-RELATED NUCLEAR ENVELOPE INTEGRAL MEMBRANE PROTEIN 2 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000014820.1|UniProtKB=W5NC94 W5NC94 PTHR43272:SF93 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ACSBG1 ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000011075.1|UniProtKB=W5MZ00 W5MZ00 PTHR13793:SF19 PHD FINGER PROTEINS BROMODOMAIN AND PHD FINGER-CONTAINING PROTEIN 3 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000014689.1|UniProtKB=W5NBS0 W5NBS0 PTHR15304:SF4 MYOD FAMILY INHIBITOR ZGC:113363 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of JNK cascade#GO:0046328;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of response to stimulus#GO:0048583 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017231.1|UniProtKB=W5NL04 W5NL04 PTHR11717:SF7 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000013624.1|UniProtKB=W5N855 W5N855 PTHR23239:SF367 INTERMEDIATE FILAMENT KERATIN 15-RELATED structural molecule activity#GO:0005198 anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;epithelium development#GO:0060429;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;morphogenesis of an epithelium#GO:0002009;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000016700.1|UniProtKB=W5NJ27 W5NJ27 PTHR12197:SF193 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD N-LYSINE METHYLTRANSFERASE SMYD2 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;circulatory system development#GO:0072359;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;heart development#GO:0007507;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000009454.1|UniProtKB=W5MT75 W5MT75 PTHR24023:SF1112 COLLAGEN ALPHA COLLAGEN ALPHA-2(IX) CHAIN PRECURSOR-RELATED structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000010405.1|UniProtKB=W5MWK1 W5MWK1 PTHR15036:SF46 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 5 developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052 plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002219.1|UniProtKB=W5M2H6 W5M2H6 PTHR23349:SF4 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 15 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000015805.1|UniProtKB=W5NFP7 W5NFP7 PTHR11814:SF19 SULFATE TRANSPORTER CHLORIDE ANION EXCHANGER secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017103.1|UniProtKB=W5NKH5 W5NKH5 PTHR47709:SF2 SHORT TRANSMEMBRANE MITOCHONDRIAL PROTEIN 1 SHORT TRANSMEMBRANE MITOCHONDRIAL PROTEIN 1 respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000014409.1|UniProtKB=W5NAT0 W5NAT0 PTHR11635:SF153 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE II-ALPHA REGULATORY SUBUNIT protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;kinase inhibitor activity#GO:0019210;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;protein kinase A binding#GO:0051018;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;protein kinase inhibitor activity#GO:0004860;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Enkephalin release#P05913>PKA#P05972;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;GABA-B receptor II signaling#P05731>PKA#P05752;Endothelin signaling pathway#P00019>PKA#P00570;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Hedgehog signaling pathway#P00025>PKA#P00682;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075 LEPOC|Ensembl=ENSLOCG00000013455.1|UniProtKB=W5N7H8 W5N7H8 PTHR45874:SF6 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-B10A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000017617.1|UniProtKB=W5NM63 W5NM63 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014350.1|UniProtKB=W5NAL2 W5NAL2 PTHR11309:SF133 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 1 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515 cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;non-canonical Wnt signaling pathway#GO:0035567 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>FrzB#P01461;Angiogenesis#P00005>FRP#P00237 LEPOC|Ensembl=ENSLOCG00000006279.1|UniProtKB=W5MGS7 W5MGS7 PTHR42884:SF28 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 7 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 LEPOC|Ensembl=ENSLOCG00000009180.1|UniProtKB=W5MS39 W5MS39 PTHR12085:SF7 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA organelle organization#GO:0006996;regulation of B cell activation#GO:0050864;cellular process#GO:0009987;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of multicellular organismal process#GO:0051239;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of lymphocyte activation#GO:0051249;cortical cytoskeleton organization#GO:0030865;microtubule cytoskeleton organization#GO:0000226 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000004277.1|UniProtKB=W5M9Q2 W5M9Q2 PTHR11639:SF142 S100 CALCIUM-BINDING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;signaling receptor binding#GO:0005102;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 positive regulation of signaling#GO:0023056;regulation of cell population proliferation#GO:0042127;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of cell population proliferation#GO:0008284;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000014804.1|UniProtKB=W5NC71 W5NC71 PTHR10288:SF162 KH DOMAIN CONTAINING RNA BINDING PROTEIN RNA-BINDING PROTEIN NOVA-2 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011669.1|UniProtKB=W5N130 W5N130 PTHR16039:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 2 microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;spindle assembly#GO:0051225;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;protein-containing complex assembly#GO:0065003;centrosome cycle#GO:0007098;protein polymerization#GO:0051258;cell cycle process#GO:0022402;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 HAUS complex#GO:0070652;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular organelle#GO:0043229;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000016352.1|UniProtKB=W5NHT4 W5NHT4 PTHR35760:SF1 SI:CH211-22I13.2 SI:CH211-22I13.2 LEPOC|Ensembl=ENSLOCG00000002690.1|UniProtKB=W5M454 W5M454 PTHR18956:SF6 HYALURONAN MEDIATED MOTILITY RECEPTOR HYALURONAN MEDIATED MOTILITY RECEPTOR LEPOC|Ensembl=ENSLOCG00000004746.1|UniProtKB=W5MBD1 W5MBD1 PTHR24383:SF12 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 618 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000010343.1|UniProtKB=W5MWB5 W5MWB5 PTHR23166:SF9 FILAMIN/GPBP-INTERACTING PROTEIN CTTNBP2 N-TERMINAL-LIKE PROTEIN intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000011007.1|UniProtKB=W5MYP5 W5MYP5 PTHR14093:SF17 HLA CLASS II GAMMA CHAIN HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN protein binding#GO:0005515;molecular transducer activity#GO:0060089;MHC protein binding#GO:0042287;binding#GO:0005488;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;cytokine receptor activity#GO:0004896 negative regulation of signal transduction#GO:0009968;lymphocyte activation#GO:0046649;positive regulation of macromolecule metabolic process#GO:0010604;regulation of ERK1 and ERK2 cascade#GO:0070372;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of cytokine-mediated signaling pathway#GO:0001959;leukocyte activation involved in immune response#GO:0002366;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;regulation of cytokine production involved in immune response#GO:0002718;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of MAPK cascade#GO:0043410;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of signal transduction#GO:0009967;regulation of immune effector process#GO:0002697;antigen processing and presentation#GO:0019882;regulation of apoptotic signaling pathway#GO:2001233;regulation of immune response#GO:0050776;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of multicellular organismal process#GO:0051239;T cell activation involved in immune response#GO:0002286;lymphocyte activation involved in immune response#GO:0002285;regulation of response to cytokine stimulus#GO:0060759;immune effector process#GO:0002252;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408;T cell activation#GO:0042110;regulation of programmed cell death#GO:0043067;cell activation involved in immune response#GO:0002263;positive regulation of cytokine-mediated signaling pathway#GO:0001961;regulation of cellular response to stress#GO:0080135;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;negative regulation of apoptotic process#GO:0043066;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stress#GO:0080134;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of cell communication#GO:0010647;positive regulation of cytokine production#GO:0001819;regulation of intrinsic apoptotic signaling pathway#GO:2001242;leukocyte activation#GO:0045321;positive regulation of biosynthetic process#GO:0009891;cell activation#GO:0001775 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 scaffold/adaptor protein#PC00226 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000000590.1|UniProtKB=W5LWZ7 W5LWZ7 PTHR12300:SF133 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 6 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000395.1|UniProtKB=W5LWC4 W5LWC4 PTHR21325:SF52 PHOSPHOLIPASE B, PLB1 PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;carboxylic ester hydrolase activity#GO:0052689;A2-type glycerophospholipase activity#GO:0004623;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 lipid metabolic process#GO:0006629;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644 cell periphery#GO:0071944;brush border#GO:0005903;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;brush border membrane#GO:0031526;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;apical part of cell#GO:0045177;cluster of actin-based cell projections#GO:0098862;cell projection membrane#GO:0031253 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000000384.1|UniProtKB=W5LWB2 W5LWB2 PTHR48051:SF2 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 39 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000018220.1|UniProtKB=W5NNW2 W5NNW2 PTHR24365:SF17 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 2 binding#GO:0005488;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;signaling receptor activity#GO:0038023 regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;cell communication#GO:0007154;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune system process#GO:0002376;toll-like receptor signaling pathway#GO:0002224;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR1,2,6#P01380;Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000002682.1|UniProtKB=W5M437 W5M437 PTHR37359:SF1 TRANSMEMBRANE PROTEIN 253 TRANSMEMBRANE PROTEIN 253 LEPOC|Ensembl=ENSLOCG00000006907.1|UniProtKB=W5MIZ5 W5MIZ5 PTHR11339:SF264 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-6 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000009271.1|UniProtKB=W5MSF1 W5MSF1 PTHR12276:SF126 EPSIN/ENT-RELATED CLATHRIN INTERACTOR 1 phospholipid binding#GO:0005543;binding#GO:0005488;clathrin binding#GO:0030276;lipid binding#GO:0008289;protein binding#GO:0005515 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933 intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vesicle coat#GO:0030120;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011155.1|UniProtKB=W5MZ97 W5MZ97 PTHR10639:SF1 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN A protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;organelle#GO:0043226;synapse#GO:0045202;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;clathrin vesicle coat#GO:0030125;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;clathrin-coated vesicle membrane#GO:0030665;presynapse#GO:0098793;secretory vesicle#GO:0099503;vesicle coat#GO:0030120;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658 vesicle coat protein#PC00235;membrane traffic protein#PC00150 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Huntington disease#P00029>Clathrin#P00798 LEPOC|Ensembl=ENSLOCG00000011121.1|UniProtKB=W5MZ56 W5MZ56 RAB37 PTHR47978:SF64 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-37 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 regulation of secretion#GO:0051046;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000008859.1|UniProtKB=W5MQW7 W5MQW7 PTHR21392:SF0 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 LEPOC|Ensembl=ENSLOCG00000016698.1|UniProtKB=W5NJ21 W5NJ21 PTHR12198:SF10 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 PROSPERO HOMEOBOX PROTEIN 1A ISOFORM X1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000005779.1|UniProtKB=W5MF24 W5MF24 PTHR46358:SF1 TONSOKU-LIKE PROTEIN TONSOKU-LIKE PROTEIN DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000002886.1|UniProtKB=W5M4Y3 W5M4Y3 PTHR18896:SF198 PHOSPHOLIPASE D PHOSPHOLIPASE D1 ISOFORM X1 hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of localization#GO:0032879;regulation of transport#GO:0051049;organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 lipase#PC00143;phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000003034.1|UniProtKB=W5M5C4 W5M5C4 PTHR10502:SF26 ANNEXIN ANNEXIN A5 phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phospholipid binding#GO:0005543;ion binding#GO:0043167 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 calcium-binding protein#PC00060 Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#G06684;Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#G06897;Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#P06814 LEPOC|Ensembl=ENSLOCG00000006495.1|UniProtKB=W5MHJ2 W5MHJ2 PTHR19972:SF4 CALBINDIN CALRETININ binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection terminus#GO:0044306;cell projection#GO:0042995;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;neuron projection#GO:0043005;presynapse#GO:0098793;nucleus#GO:0005634;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;cell junction#GO:0030054;axon terminus#GO:0043679 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000001828.1|UniProtKB=W5M166 W5M166 PTHR21650:SF4 MEMBRALIN/KINETOCHORE PROTEIN NUF2 MEMBRALIN regulation of response to endoplasmic reticulum stress#GO:1905897;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of ERAD pathway#GO:1904292;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein metabolic process#GO:0051247;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000007333.1|UniProtKB=W5MKH2 W5MKH2 PTHR19143:SF225 FIBRINOGEN/TENASCIN/ANGIOPOEITIN MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 4 extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;extracellular structure organization#GO:0043062 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000000278.1|UniProtKB=W5LVZ8 W5LVZ8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000004703.1|UniProtKB=W5MB79 W5MB79 PTHR22948:SF65 TUDOR DOMAIN CONTAINING PROTEIN A-KINASE ANCHORING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237 membrane#GO:0016020;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009538.1|UniProtKB=W5MTF0 W5MTF0 PTHR24409:SF308 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 11 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013146.1|UniProtKB=W5N6D5 W5N6D5 PTHR12326:SF5 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 1 LEPOC|Ensembl=ENSLOCG00000008519.1|UniProtKB=W5MPR2 W5MPR2 PTHR13526:SF8 TRANSCRIPTION FACTOR SPT20 HOMOLOG SPT20 HOMOLOG, SAGA COMPLEX COMPONENT-RELATED transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017710.1|UniProtKB=W5NMF6 W5NMF6 PTHR24299:SF4 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1C1 monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 secondary metabolic process#GO:0019748;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular response to xenobiotic stimulus#GO:0071466;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;response to chemical#GO:0042221;hormone metabolic process#GO:0042445;cellular process#GO:0009987;lipid catabolic process#GO:0016042;regulation of biological quality#GO:0065008;steroid catabolic process#GO:0006706;estrogen metabolic process#GO:0008210;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;xenobiotic metabolic process#GO:0006805;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008465.1|UniProtKB=W5MPJ5 W5MPJ5 PTHR22050:SF2 RW1 PROTEIN HOMOLOG TRANSMEMBRANE PROTEIN 131-LIKE negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biosynthetic process#GO:0009058;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000004874.1|UniProtKB=W5MBU7 W5MBU7 PTHR14387:SF0 THADA/DEATH RECEPTOR INTERACTING PROTEIN DUF2428 DOMAIN-CONTAINING PROTEIN enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA methylation#GO:0001510;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004171.1|UniProtKB=W5M9C6 W5M9C6 PTHR20981:SF6 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000012068.1|UniProtKB=W5N2I9 W5N2I9 PTHR24197:SF50 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 54 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000006795.1|UniProtKB=W5MIM8 W5MIM8 PTHR14042:SF23 DOPEY-RELATED PROTEIN DOP1B endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;retrograde transport, vesicle recycling within Golgi#GO:0000301 early endosome membrane#GO:0031901;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004923.1|UniProtKB=W5MC14 W5MC14 PTHR12940:SF0 ES-2 PROTEIN - RELATED SPLICING FACTOR ESS-2 HOMOLOG intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000004366.1|UniProtKB=W5MA05 W5MA05 PTHR24068:SF129 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBE2F ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004562.1|UniProtKB=W5MAQ3 W5MAQ3 PTHR10827:SF17 RETICULOCALBIN RETICULOCALBIN-1 metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000005800.1|UniProtKB=W5MF46 W5MF46 PTHR24115:SF744 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3B hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777 cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;microtubule-based process#GO:0007017;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000009956.1|UniProtKB=W5MUW7 W5MUW7 PTHR39490:SF8 ARRESTIN DOMAIN-CONTAINING PROTEIN D ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21 LEPOC|Ensembl=ENSLOCG00000003512.1|UniProtKB=W5M6Z7 W5M6Z7 PTHR10417:SF3 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 1 sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001650.1|UniProtKB=W5M0J7 W5M0J7 PTHR24020:SF86 COLLAGEN ALPHA COLLAGEN TYPE VI ALPHA 6 CHAIN cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000001630.1|UniProtKB=W5M0G8 W5M0G8 PTHR46424:SF1 UBX DOMAIN-CONTAINING PROTEIN 4 UBX DOMAIN-CONTAINING PROTEIN 4 response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006278.1|UniProtKB=W5MGT4 W5MGT4 PTHR10627:SF34 SCP160 VIGILIN mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012381.1|UniProtKB=W5N3N4 W5N3N4 PTHR10868:SF4 SIGMA 1-TYPE OPIOID RECEPTOR-RELATED SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of programmed cell death#GO:0043067;regulation of neuron apoptotic process#GO:0043523;regulation of biological process#GO:0050789;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of cellular response to stress#GO:0080135 cell junction#GO:0030054;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;postsynaptic specialization#GO:0099572;endomembrane system#GO:0012505;neuron to neuron synapse#GO:0098984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017274.1|UniProtKB=W5NL57 W5NL57 PTHR12691:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000013386.1|UniProtKB=W5N792 W5N792 PTHR23266:SF345 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA CONSTANT 6 binding#GO:0005488;antigen binding#GO:0003823 immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003885.1|UniProtKB=W5M8E0 W5M8E0 PTHR24023:SF1073 COLLAGEN ALPHA COLLAGEN ALPHA-3(IX) CHAIN PRECURSOR structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000008940.1|UniProtKB=W5MR82 W5MR82 PTHR11588:SF278 TUBULIN TUBULIN ALPHA CHAIN-LIKE 3 binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;tubulin#PC00228 LEPOC|Ensembl=ENSLOCG00000010784.1|UniProtKB=W5MXV2 W5MXV2 PTHR22380:SF1 TESTIS-EXPRESSED PROTEIN 15 TESTIS-EXPRESSED PROTEIN 15 male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;cell cycle#GO:0007049;organelle fission#GO:0048285;multicellular organismal reproductive process#GO:0048609;regulation of double-strand break repair#GO:2000779;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;cellular component assembly#GO:0022607;synaptonemal complex assembly#GO:0007130;homologous chromosome pairing at meiosis#GO:0007129;male meiotic nuclear division#GO:0007140;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;gamete generation#GO:0007276;regulation of double-strand break repair via homologous recombination#GO:0010569;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;regulation of DNA metabolic process#GO:0051052;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;nuclear division#GO:0000280;regulation of DNA recombination#GO:0000018 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000009643.1|UniProtKB=W5MTS9 W5MTS9 PTHR24020:SF36 COLLAGEN ALPHA COCHLIN system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000010242.1|UniProtKB=W5MW17 W5MW17 PTHR14514:SF4 PKA ANCHORING PROTEIN NESPRIN-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;establishment of organelle localization#GO:0051656;centrosome localization#GO:0051642;regulation of cellular component biogenesis#GO:0044087;regulation of biological process#GO:0050789;nuclear migration#GO:0007097;regulation of organelle organization#GO:0033043;localization#GO:0051179;cellular localization#GO:0051641;regulation of cell projection assembly#GO:0060491;organelle localization#GO:0051640;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;regulation of plasma membrane bounded cell projection organization#GO:0120035;establishment of localization#GO:0051234;regulation of cell projection organization#GO:0031344;intracellular transport#GO:0046907;regulation of cilium assembly#GO:1902017;transport#GO:0006810 myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membraneless organelle#GO:0043228;sarcomere#GO:0030017;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;endoplasmic reticulum#GO:0005783;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;nucleus#GO:0005634;sarcoplasmic reticulum#GO:0016529;contractile muscle fiber#GO:0043292 LEPOC|Ensembl=ENSLOCG00000005022.1|UniProtKB=W5MCE2 W5MCE2 PTHR19229:SF113 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 13 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000011364.1|UniProtKB=W5N007 W5N007 PTHR22929:SF0 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B TRANSCRIPTION FACTOR TFIIIB COMPONENT B'' HOMOLOG general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013392.1|UniProtKB=W5N7A1 W5N7A1 PTHR23268:SF28 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 27 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015495.1|UniProtKB=W5NEL0 W5NEL0 PTHR11309:SF11 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 2 molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;non-canonical Wnt signaling pathway#GO:0035567 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010957.1|UniProtKB=W5MYI2 W5MYI2 PTHR45732:SF13 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8B microtubule-based process#GO:0007017;endosomal transport#GO:0016197;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;anterograde axonal transport#GO:0008089;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;lysosomal transport#GO:0007041;axonal transport#GO:0098930;microtubule-based movement#GO:0007018 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323 LEPOC|Ensembl=ENSLOCG00000006985.1|UniProtKB=W5MJ97 W5MJ97 PTHR22884:SF293 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE NSD2 histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000000787.1|UniProtKB=W5LXL7 W5LXL7 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000016541.1|UniProtKB=W5NIG9 W5NIG9 PTHR46423:SF1 RNA POLYMERASE II-ASSOCIATED PROTEIN 3 RNA POLYMERASE II-ASSOCIATED PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000007231.1|UniProtKB=W5MK44 W5MK44 PTHR10404:SF85 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2 catalytic activity#GO:0003824;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000014524.1|UniProtKB=W5NB65 W5NB65 PTHR23348:SF42 PERIAXIN/AHNAK PERIAXIN regulation of biological process#GO:0050789;peripheral nervous system development#GO:0007422;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;plasma membrane organization#GO:0007009;anatomical structure development#GO:0048856;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;regulation of RNA splicing#GO:0043484;membrane organization#GO:0061024;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;developmental process#GO:0032502;gliogenesis#GO:0042063;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;myelination#GO:0042552;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000017653.1|UniProtKB=W5NM99 W5NM99 PTHR26451:SF52 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 12D2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014099.1|UniProtKB=W5N9R9 W5N9R9 PTHR43195:SF3 TRANSKETOLASE TRANSKETOLASE heterocyclic compound binding#GO:1901363;transketolase or transaldolase activity#GO:0016744;transferase activity#GO:0016740;catalytic activity#GO:0003824;cation binding#GO:0043169;transketolase activity#GO:0004802;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;pentose-phosphate shunt, non-oxidative branch#GO:0009052;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;NADPH regeneration#GO:0006740;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pyridine-containing compound metabolic process#GO:0072524;pentose-phosphate shunt#GO:0006098;nucleotide metabolic process#GO:0009117 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transketolase#PC00221;metabolite interconversion enzyme#PC00262 Pentose phosphate pathway#P02762>Transketolase#P03082 LEPOC|Ensembl=ENSLOCG00000005579.1|UniProtKB=W5MED0 W5MED0 PTHR11532:SF73 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002895.1|UniProtKB=W5M4U7 W5M4U7 PTHR21740:SF0 NCK-ASSOCIATED PROTEIN 5 NCK-ASSOCIATED PROTEIN 5 cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;microtubule depolymerization#GO:0007019;microtubule bundle formation#GO:0001578;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular component disassembly#GO:0022411 microtubule#GO:0005874;microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752 LEPOC|Ensembl=ENSLOCG00000012743.1|UniProtKB=W5N4W7 W5N4W7 PTHR14696:SF2 HERMANSKY-PUDLAK SYNDROME 6 PROTEIN BLOC-2 COMPLEX MEMBER HPS6 organelle localization#GO:0051640;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;lysosome localization#GO:0032418;cellular process#GO:0009987 vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosomal membrane#GO:0005765;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764 LEPOC|Ensembl=ENSLOCG00000016751.1|UniProtKB=W5NJ97 W5NJ97 PTHR24418:SF390 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000017593.1|UniProtKB=W5NM39 W5NM39 PTHR46280:SF4 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 1 ion binding#GO:0043167;binding#GO:0005488;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;small molecule binding#GO:0036094 cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;endosome organization#GO:0007032;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000005936.1|UniProtKB=W5MFK9 W5MFK9 PTHR12968:SF1 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 1 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;ciliary transition zone#GO:0035869;cilium#GO:0005929;membrane-bounded organelle#GO:0043227 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010819.1|UniProtKB=W5MY04 W5MY04 PTHR18935:SF7 GOLGIN SUBFAMILY A MEMBER 4-LIKE ISOFORM X1 JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000005897.1|UniProtKB=W5MFG6 W5MFG6 PTHR36542:SF2 GIG2-LIKE PROTEIN DRED-RELATED GIG2-LIKE PROTEIN DREF-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004062.1|UniProtKB=W5M8Z3 W5M8Z3 PTHR11753:SF34 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP COMPLEX SUBUNIT SIGMA cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014664.1|UniProtKB=W5NBN9 W5NBN9 PTHR12400:SF106 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE C phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000013750.1|UniProtKB=W5N8J7 W5N8J7 PTHR10656:SF48 CELL FATE DETERMINING PROTEIN MAB21-RELATED TRANSMEMBRANE PROTEIN 102 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 nucleotidyltransferase#PC00174;transferase#PC00220 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000016321.1|UniProtKB=W5NHP0 W5NHP0 PTHR24115:SF734 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3C protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000015376.1|UniProtKB=W5NE67 W5NE67 PTHR24223:SF173 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000014585.1|UniProtKB=W5NBE2 W5NBE2 PTHR12701:SF15 BCR-ASSOCIATED PROTEIN, BAP B-CELL RECEPTOR-ASSOCIATED PROTEIN 31 protein carrier activity#GO:0140597;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;positive regulation of protein metabolic process#GO:0051247;protein transport#GO:0015031;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to endoplasmic reticulum stress#GO:0034976;positive regulation of protein catabolic process#GO:0045732;ERAD pathway#GO:0036503;regulation of protein catabolic process#GO:0042176;localization#GO:0051179;protein metabolic process#GO:0019538;positive regulation of cellular process#GO:0048522;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;transport#GO:0006810;intracellular protein localization#GO:0008104;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006773.1|UniProtKB=W5MIH3 W5MIH3 PTHR23189:SF6 RNA RECOGNITION MOTIF-CONTAINING RIBONUCLEOPROTEIN PTB-BINDING 2 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011248.1|UniProtKB=W5MZM8 W5MZM8 PTHR12287:SF22 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8-LIKE PROTEIN 3 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of cellular component biogenesis#GO:0044087;response to stimulus#GO:0050896;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;regulation of cell projection assembly#GO:0060491;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;positive regulation of cell projection organization#GO:0031346;regulation of intracellular signal transduction#GO:1902531;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344 ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;ruffle#GO:0001726;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006466.1|UniProtKB=W5MHF3 W5MHF3 PTHR46032:SF5 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 2 glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009405.1|UniProtKB=W5MSW5 W5MSW5 PTHR24306:SF0 FAMILY NOT NAMED 7-ALPHA-HYDROXYCHOLEST-4-EN-3-ONE 12-ALPHA-HYDROXYLASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 LEPOC|Ensembl=ENSLOCG00000015036.1|UniProtKB=W5NCZ5 W5NCZ5 PTHR46599:SF9 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED 4-RELATED viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000015245.1|UniProtKB=W5NDQ3 W5NDQ3 PTHR12064:SF27 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001410.1|UniProtKB=W5LZQ0 W5LZQ0 PTHR22776:SF89 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 7 toll-like receptor signaling pathway#GO:0002224;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;lymphocyte activation#GO:0046649;regulation of response to external stimulus#GO:0032101;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;B cell activation#GO:0042113;leukocyte activation#GO:0045321;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell activation#GO:0001775;cell communication#GO:0007154;activation of innate immune response#GO:0002218;immune response#GO:0006955;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007957.1|UniProtKB=W5MMQ9 W5MMQ9 ASNA1 PTHR10803:SF3 ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE ATPASE GET3 ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048 intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009505.1|UniProtKB=W5MTB5 W5MTB5 PTHR15735:SF14 FCH AND DOUBLE SH3 DOMAINS PROTEIN FORMIN-BINDING PROTEIN 1-LIKE cellular process#GO:0009987;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;regulation of actin cytoskeleton organization#GO:0032956;vesicle-mediated transport#GO:0016192;membrane invagination#GO:0010324;transport#GO:0006810;regulation of actin filament-based process#GO:0032970;receptor-mediated endocytosis#GO:0006898;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;regulation of biological process#GO:0050789;clathrin-dependent endocytosis#GO:0072583;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;localization#GO:0051179;plasma membrane organization#GO:0007009 cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000011102.1|UniProtKB=W5MZ42 W5MZ42 PTHR24055:SF107 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 13 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;EGF receptor signaling pathway#P00018>p38#P00562;TGF-beta signaling pathway#P00052>P38#P01275;B cell activation#P00010>p38#P00384;FGF signaling pathway#P00021>p38#P00644;p38 MAPK pathway#P05918>p38delta#P06020;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Integrin signalling pathway#P00034>ERK#P00907;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Ras Pathway#P04393>p38#P04558;Oxidative stress response#P00046>p38#P01135 LEPOC|Ensembl=ENSLOCG00000015130.1|UniProtKB=W5NDB3 W5NDB3 PTHR11817:SF101 PYRUVATE KINASE PYRUVATE KINASE PKM transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;pyruvate kinase activity#GO:0004743;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;response to hormone#GO:0009725;response to chemical#GO:0042221;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;ribonucleoside diphosphate metabolic process#GO:0009185;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;cellular response to nitrogen compound#GO:1901699;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;carbohydrate metabolic process#GO:0005975;cellular response to peptide hormone stimulus#GO:0071375;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;response to nitrogen compound#GO:1901698;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;cellular response to oxygen-containing compound#GO:1901701;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;cellular response to chemical stimulus#GO:0070887;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;response to peptide hormone#GO:0043434;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;cellular response to insulin stimulus#GO:0032869;ADP metabolic process#GO:0046031;purine nucleoside triphosphate metabolic process#GO:0009144;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137 Glycolysis#P00024>Pyruvate kinase#P00675;Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 LEPOC|Ensembl=ENSLOCG00000006271.1|UniProtKB=W5MGR5 W5MGR5 PTHR15127:SF33 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN D protein binding#GO:0005515;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000017869.1|UniProtKB=W5NMW3 W5NMW3 PTHR11309:SF79 FRIZZLED FRIZZLED-9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 non-canonical Wnt signaling pathway#GO:0035567;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 LEPOC|Ensembl=ENSLOCG00000004081.1|UniProtKB=W5M948 W5M948 PTHR22957:SF187 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 1 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000004826.1|UniProtKB=W5MBN4 W5MBN4 PTHR14689:SF0 PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 82 LEPOC|Ensembl=ENSLOCG00000009527.1|UniProtKB=W5MTE2 W5MTE2 PTHR12300:SF29 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 2 protein binding#GO:0005515;microtubule binding#GO:0008017;signaling receptor binding#GO:0005102;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;G protein-coupled receptor binding#GO:0001664 endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;endoplasmic reticulum tubular network organization#GO:0071786;cellular component organization or biogenesis#GO:0071840 supramolecular complex#GO:0099080;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;endoplasmic reticulum tubular network#GO:0071782;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;organelle membrane#GO:0031090;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015507.1|UniProtKB=W5NEM5 W5NEM5 PTHR10887:SF419 DNA2/NAM7 HELICASE FAMILY RNA HELICASE MOV10L1 ISOFORM X1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194 membraneless organelle#GO:0043228;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000006860.1|UniProtKB=W5MIV6 W5MIV6 PTHR14139:SF4 CALSYNTENIN CALSYNTENIN-1 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 regulation of synapse assembly#GO:0051963;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of synapse assembly#GO:0051965;positive regulation of developmental process#GO:0051094;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130;cell adhesion#GO:0007155;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;cell surface#GO:0009986;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000986.1|UniProtKB=W5LYA3 W5LYA3 PTHR45948:SF1 DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED TYROSINE-PROTEIN PHOSPHATASE DOMAIN-CONTAINING PROTEIN protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000007902.1|UniProtKB=W5MMI7 W5MMI7 PTHR12704:SF4 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3-LIKE phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;lipid binding#GO:0008289;cargo adaptor activity#GO:0140312;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 protein localization to cell periphery#GO:1990778;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;Golgi organization#GO:0007030;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000004339.1|UniProtKB=W5M9Y3 W5M9Y3 PTHR12695:SF2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;response to stimulus#GO:0050896;DNA-templated transcription initiation#GO:0006352;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;nucleotide-excision repair#GO:0006289;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transcription factor TFIIH core complex#GO:0000439;transferase complex#GO:1990234 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016162.1|UniProtKB=W5NH18 W5NH18 PTHR12268:SF26 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 UTROPHIN cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;neuromuscular junction development#GO:0007528;cellular component organization#GO:0016043;synapse organization#GO:0050808;cellular process#GO:0009987 synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;neuromuscular junction#GO:0031594;cell junction#GO:0030054 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002304.1|UniProtKB=W5M2V4 W5M2V4 PTHR23255:SF55 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-2 signaling receptor binding#GO:0005102;molecular transducer activity#GO:0060089;transforming growth factor beta binding#GO:0050431;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;cytokine binding#GO:0019955;transmembrane receptor protein kinase activity#GO:0019199;binding#GO:0005488;cytokine receptor binding#GO:0005126;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;transferase activity#GO:0016740;kinase activity#GO:0016301;activin binding#GO:0048185;transforming growth factor beta receptor activity#GO:0005024;signaling receptor activity#GO:0038023 developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;multicellular organism development#GO:0007275;animal organ development#GO:0048513;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;activin receptor signaling pathway#GO:0032924;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;transferase complex#GO:1990234;catalytic complex#GO:1902494;signaling receptor complex#GO:0043235;transferase complex, transferring phosphorus-containing groups#GO:0061695 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283 LEPOC|Ensembl=ENSLOCG00000009340.1|UniProtKB=W5MSN5 W5MSN5 PTHR13609:SF20 UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED UBIQUITIN DOMAIN-CONTAINING PROTEIN 2 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000000167.1|UniProtKB=W5LVM9 W5LVM9 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010460.1|UniProtKB=W5MWR1 W5MWR1 PTHR22808:SF8 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(34)-C(5))-METHYLTRANSFERASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000012561.1|UniProtKB=W5N4B9 W5N4B9 PTHR24347:SF398 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT GAMMA phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;calmodulin binding#GO:0005516;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of synaptic plasticity#GO:0048167;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuronal synaptic plasticity#GO:0048168;regulation of localization#GO:0032879;regulation of protein localization to membrane#GO:1905475;regulation of neuron projection development#GO:0010975;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;postsynaptic density#GO:0014069;axon#GO:0030424;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;neuron projection#GO:0043005 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 LEPOC|Ensembl=ENSLOCG00000008053.1|UniProtKB=W5MN21 W5MN21 PTHR28567:SF1 PROTEIN FAM53A-LIKE ISOFORM X1 PROTEIN FAM53B positive regulation of Wnt signaling pathway#GO:0030177;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular protein transport#GO:0006886;regulation of Wnt signaling pathway#GO:0030111;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;protein import into nucleus#GO:0006606;protein transport#GO:0015031;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;positive regulation of cellular process#GO:0048522;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;positive regulation of canonical Wnt signaling pathway#GO:0090263;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;regulation of response to stimulus#GO:0048583;protein localization to organelle#GO:0033365;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;localization#GO:0051179;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000006669.1|UniProtKB=W5MI46 W5MI46 PTHR11309:SF97 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>FrzB#P01461;Angiogenesis#P00005>FRP#P00237 LEPOC|Ensembl=ENSLOCG00000009252.1|UniProtKB=W5MSC7 W5MSC7 PTHR15454:SF75 NISCHARIN RELATED SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004192.1|UniProtKB=W5M9E9 W5M9E9 PTHR18881:SF2 POLYAMINE-MODULATED FACTOR 1-BINDING PROTEIN 1-RELATED POLYAMINE-MODULATED FACTOR 1-BINDING PROTEIN 1 developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproductive process#GO:0022414;developmental process#GO:0032502;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609 cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007986.1|UniProtKB=W5MMU1 W5MMU1 PTHR16105:SF0 RNA-BINDING REGION-CONTAINING PROTEIN 3 RNA-BINDING REGION-CONTAINING PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488;pre-mRNA binding#GO:0036002;RNA binding#GO:0003723;snRNA binding#GO:0017069 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398 U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000010583.1|UniProtKB=W5MX56 W5MX56 PTHR24366:SF61 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 52 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000003042.1|UniProtKB=W5M5C0 W5M5C0 MED18 PTHR13321:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 18 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000007873.1|UniProtKB=W5MMF0 W5MMF0 PTHR35257:SF1 TRANSMEMBRANE PROTEIN 82 TRANSMEMBRANE PROTEIN 82 LEPOC|Ensembl=ENSLOCG00000011049.1|UniProtKB=W5MYW0 W5MYW0 PTHR19924:SF26 UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;rRNA processing#GO:0006364;regulation of transcription by RNA polymerase I#GO:0006356;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;rRNA metabolic process#GO:0016072;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase I#GO:0045943;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010701.1|UniProtKB=W5MXK3 W5MXK3 PTHR12198:SF9 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 PROSPERO HOMEOBOX PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011882.1|UniProtKB=W5N1U9 W5N1U9 PTHR37476:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 171 COILED-COIL DOMAIN-CONTAINING PROTEIN 171 LEPOC|Ensembl=ENSLOCG00000014245.1|UniProtKB=W5NA79 W5NA79 PTHR46197:SF1 PROTEIN ABHD14B-LIKE PROTEIN ABHD14A cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000009978.1|UniProtKB=W5MUZ8 W5MUZ8 PTHR12948:SF3 NEDD8 ULTIMATE BUSTER-1 BS4 PROTEIN NEDD8 ULTIMATE BUSTER 1 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of catabolic process#GO:0009894;regulation of protein catabolic process#GO:0042176 LEPOC|Ensembl=ENSLOCG00000017197.1|UniProtKB=W5NKU9 W5NKU9 PTHR11785:SF340 AMINO ACID TRANSPORTER AROMATIC-PREFERRING AMINO ACID TRANSPORTER amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;L-amino acid transmembrane transporter activity#GO:0015179 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013936.1|UniProtKB=W5N973 W5N973 PTHR20974:SF1 UPF0585 PROTEIN CG18661 METHYLTRANSFERASE-LIKE 26 B LEPOC|Ensembl=ENSLOCG00000013080.1|UniProtKB=W5N652 W5N652 PTHR11551:SF3 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 3 protein binding#GO:0005515;growth factor binding#GO:0019838;binding#GO:0005488 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 p53 pathway#P00059>IGF-BP3#G04691 LEPOC|Ensembl=ENSLOCG00000000516.1|UniProtKB=W5LWR4 W5LWR4 PTHR45013:SF1 NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1 NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011584.1|UniProtKB=W5N0S4 W5N0S4 PTHR24390:SF135 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 740 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000015084.1|UniProtKB=W5ND56 W5ND56 PTHR14009:SF7 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN LETM1 DOMAIN-CONTAINING PROTEIN LETM2, MITOCHONDRIAL transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic cation transmembrane transport#GO:0098655;mitochondrion organization#GO:0007005;monoatomic ion transmembrane transport#GO:0034220;organelle organization#GO:0006996;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;cellular component organization#GO:0016043;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000011402.1|UniProtKB=W5N068 W5N068 PTHR11451:SF54 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000002385.1|UniProtKB=W5M335 W5M335 PTHR22977:SF5 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN HOMOLOG intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012746.1|UniProtKB=W5N4X6 W5N4X6 PTHR13608:SF3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011256.1|UniProtKB=W5MZN2 W5MZN2 PTHR24412:SF441 KELCH PROTEIN KELCH-LIKE PROTEIN 28 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011077.1|UniProtKB=W5MYZ0 W5MYZ0 PTHR34648:SF6 CLOCK-INTERACTING PACEMAKER CLOCK-INTERACTING PACEMAKER-RELATED negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000520.1|UniProtKB=W5LWS9 W5LWS9 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011176.1|UniProtKB=W5MZC4 W5MZC4 PTHR22761:SF12 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 5 vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;nucleus organization#GO:0006997;establishment of localization in cell#GO:0051649;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nuclear membrane organization#GO:0071763;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular localization#GO:0051641;membrane assembly#GO:0071709;cellular component organization#GO:0016043;late endosome to vacuole transport#GO:0045324 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014509.1|UniProtKB=W5NB47 W5NB47 PTHR45624:SF11 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL ORNITHINE TRANSPORTER 1 ISOFORM X1 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;L-alpha-amino acid transmembrane transport#GO:1902475;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;establishment of localization#GO:0051234;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000752.1|UniProtKB=W5LXI1 W5LXI1 PTHR10411:SF5 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 BETA protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 positive regulation of MAPK cascade#GO:0043410;regulation of JNK cascade#GO:0046328;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 p53 pathway#P00059>GADD45#P04626;p53 pathway#P00059>GADD45#G01575 LEPOC|Ensembl=ENSLOCG00000009829.1|UniProtKB=W5MUF8 W5MUF8 PTHR13318:SF19 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 5 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 catalytic complex#GO:1902494;transferase complex#GO:1990234;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 LEPOC|Ensembl=ENSLOCG00000017506.1|UniProtKB=W5NLV2 W5NLV2 PTHR19290:SF32 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED OLIGODENDROCYTE TRANSCRIPTION FACTOR 2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;plasma membrane bounded cell projection organization#GO:0120036;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000012809.1|UniProtKB=W5N563 W5N563 PTHR45836:SF3 SLIT HOMOLOG SLIT HOMOLOG 1 PROTEIN heparin binding#GO:0008201;binding#GO:0005488;signaling receptor binding#GO:0005102;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;protein binding#GO:0005515 multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;anatomical structure development#GO:0048856;system development#GO:0048731;chemotaxis#GO:0006935;response to chemical#GO:0042221;taxis#GO:0042330;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 LEPOC|Ensembl=ENSLOCG00000006631.1|UniProtKB=W5MI03 W5MI03 PTHR14167:SF63 SH3 DOMAIN-CONTAINING ENDOPHILIN-A2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;presynapse#GO:0098793;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015896.1|UniProtKB=W5NG15 W5NG15 PTHR15140:SF31 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE E protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000480.1|UniProtKB=W5LWM0 W5LWM0 PTHR46985:SF8 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD-RELATED peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;signaling receptor activity#GO:0038023;molecular function regulator activity#GO:0098772;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;molecular function activator activity#GO:0140677;pattern recognition receptor activity#GO:0038187;enzyme regulator activity#GO:0030234;molecular transducer activity#GO:0060089 regulation of innate immune response#GO:0045088;apoptotic signaling pathway#GO:0097190;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;inflammatory response#GO:0006954;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;intrinsic apoptotic signaling pathway#GO:0097193;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;apoptotic process#GO:0006915 canonical inflammasome complex#GO:0061702;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000009923.1|UniProtKB=W5MUS8 W5MUS8 PTHR24355:SF11 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RHODOPSIN KINASE GRK1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin kinase#P00750 LEPOC|Ensembl=ENSLOCG00000016599.1|UniProtKB=W5NIP3 W5NIP3 PTHR22930:SF237 FAMILY NOT NAMED SI:CH73-257C13.2 LEPOC|Ensembl=ENSLOCG00000015577.1|UniProtKB=W5NEW9 W5NEW9 PTHR16089:SF13 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 3 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003624.1|UniProtKB=W5M7G2 W5M7G2 PTHR24098:SF11 OUTER SEGMENT 5 INTRAFLAGELLAR TRANSPORT PROTEIN 80 HOMOLOG plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intraciliary transport particle B#GO:0030992;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000005790.1|UniProtKB=W5MF33 W5MF33 PTHR11776:SF7 ADENINE PHOSPHORIBOSYLTRANSFERASE ADENINE PHOSPHORIBOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 transferase#PC00220 Salvage pyrimidine ribonucleotides#P02775>Uracil phosphoribosyl transferase#P03151;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphoribosyl transferase#P02810 LEPOC|Ensembl=ENSLOCG00000005560.1|UniProtKB=W5MEA3 W5MEA3 PTHR11588:SF6 TUBULIN TUBULIN DELTA CHAIN purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl nucleotide binding#GO:0019001;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;tubulin#PC00228 LEPOC|Ensembl=ENSLOCG00000005267.1|UniProtKB=W5MD90 W5MD90 PTHR15495:SF7 NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED GPI INOSITOL-DEACYLASE catalytic activity#GO:0003824;deacylase activity#GO:0160215 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000807.1|UniProtKB=W5LXP7 W5LXP7 PTHR16675:SF237 MHC CLASS I-RELATED MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010946.1|UniProtKB=W5MYH5 W5MYH5 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to other organism#GO:0051707;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010887.1|UniProtKB=W5MY91 W5MY91 PTHR47958:SF11 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 sexual reproduction#GO:0019953;developmental process#GO:0032502;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;germ cell development#GO:0007281;cellular process#GO:0009987;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell differentiation#GO:0030154;gamete generation#GO:0007276 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000012191.1|UniProtKB=W5N2Y2 W5N2Y2 PTHR11818:SF107 BETA/GAMMA CRYSTALLIN CRYGMX PROTEIN structural molecule activity#GO:0005198 multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877;visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011699.1|UniProtKB=W5N167 W5N167 PTHR11537:SF246 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 4-RELATED gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;metal ion transport#GO:0030001;action potential#GO:0001508;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 axon terminus#GO:0043679;voltage-gated potassium channel complex#GO:0008076;neuron projection membrane#GO:0032589;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;neuron projection terminus#GO:0044306;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;cell leading edge#GO:0031252;presynapse#GO:0098793;neuron projection#GO:0043005;cell projection membrane#GO:0031253;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;postsynapse#GO:0098794;cell body#GO:0044297 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000007985.1|UniProtKB=W5MMT5 W5MMT5 PTHR13593:SF33 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 3 phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000005046.1|UniProtKB=W5MCG4 W5MCG4 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014381.1|UniProtKB=W5NAP6 W5NAP6 PTHR11987:SF30 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8B catalytic activity#GO:0003824;transferase activity#GO:0016740;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;oligosaccharide metabolic process#GO:0009311 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006241.1|UniProtKB=W5MGM8 W5MGM8 PTHR20963:SF57 MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000016942.1|UniProtKB=W5NJY4 W5NJY4 PTHR24068:SF581 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 response to chemical#GO:0042221;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;protein modification by small protein conjugation or removal#GO:0070647;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000017226.1|UniProtKB=W5NKZ7 W5NKZ7 PTHR35663:SF1 TESTIS DEVELOPMENT-RELATED PROTEIN-RELATED TESTIS DEVELOPMENT-RELATED PROTEIN multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;developmental process#GO:0032502;spermatogenesis#GO:0007283;reproductive process#GO:0022414;male gamete generation#GO:0048232;gamete generation#GO:0007276;developmental process involved in reproduction#GO:0003006 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000018296.1|UniProtKB=W5NP38 W5NP38 PTHR22750:SF20 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 5 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015559.1|UniProtKB=W5NEU3 W5NEU3 PTHR31423:SF3 YBAK DOMAIN-CONTAINING PROTEIN PROLYL-TRNA SYNTHETASE ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED LEPOC|Ensembl=ENSLOCG00000010074.1|UniProtKB=W5MVB4 W5MVB4 PTHR45726:SF1 LEUKOTRIENE A-4 HYDROLASE AMINOPEPTIDASE B metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000010660.1|UniProtKB=W5MXE4 W5MXE4 PTHR15907:SF4 DUF614 FAMILY PROTEIN-RELATED PLACENTA ASSOCIATED 8, TANDEM DUPLICATE 2-RELATED regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 LEPOC|Ensembl=ENSLOCG00000013632.1|UniProtKB=W5N846 W5N846 PTHR23036:SF101 CYTOKINE RECEPTOR INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-2 cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 LEPOC|Ensembl=ENSLOCG00000006117.1|UniProtKB=W5MG87 W5MG87 PTHR24056:SF0 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 7 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472 biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;regulation of cell cycle#GO:0051726;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;DNA-templated transcription initiation#GO:0006352;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription factor TFIIH holo complex#GO:0005675;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transcription regulator complex#GO:0005667 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000000004.1|UniProtKB=W5LV47 W5LV47 PTHR48094:SF18 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006209.1|UniProtKB=W5MGJ1 W5MGJ1 PTHR18966:SF407 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2A monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;voltage-gated monoatomic ion channel activity#GO:0005244;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;cell surface receptor signaling pathway#GO:0007166;regulation of membrane potential#GO:0042391;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;nervous system process#GO:0050877;regulation of signaling#GO:0023051;positive regulation of synaptic transmission#GO:0050806;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of synaptic plasticity#GO:0048167;system process#GO:0003008;regulation of postsynaptic membrane potential#GO:0060078;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;chemical synaptic transmission, postsynaptic#GO:0099565;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transporter complex#GO:1990351;cell junction#GO:0030054;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NR2C#P01006;Ionotropic glutamate receptor pathway#P00037>NR2B#P01007;Ionotropic glutamate receptor pathway#P00037>NR2A#P01008;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Huntington disease#P00029>NMDA receptor#P00778;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039 LEPOC|Ensembl=ENSLOCG00000011931.1|UniProtKB=W5N212 W5N212 PTHR33861:SF3 PROTEIN CBG18333 MEIOSIS-SPECIFIC COILED-COIL DOMAIN-CONTAINING PROTEIN MEIOC negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;gamete generation#GO:0007276;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;nuclear division#GO:0000280;mRNA stabilization#GO:0048255;male meiotic nuclear division#GO:0007140;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;meiotic cell cycle#GO:0051321;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;negative regulation of catabolic process#GO:0009895;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;regulation of RNA stability#GO:0043487;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;male gamete generation#GO:0048232;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;meiotic nuclear division#GO:0140013;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013513.1|UniProtKB=W5N7Q6 W5N7Q6 PTHR12245:SF15 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013340.1|UniProtKB=W5N736 W5N736 PTHR16207:SF1 SET DOMAIN-CONTAINING PROTEIN PROTEIN TASOR chromatin binding#GO:0003682;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;localization#GO:0051179;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;macromolecule localization#GO:0033036;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;intracellular protein localization#GO:0008104;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000004461.1|UniProtKB=W5MAC0 W5MAC0 PTHR16138:SF7 MYCOPHENOLIC ACID ACYL-GLUCURONIDE ESTERASE, MITOCHONDRIAL PALMITOYL-PROTEIN THIOESTERASE ABHD10, MITOCHONDRIAL hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;palmitoyl hydrolase activity#GO:0098599;thiolester hydrolase activity#GO:0016790 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 esterase#PC00097;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015836.1|UniProtKB=W5NFT5 W5NFT5 PTHR14332:SF3 DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;cilium organization#GO:0044782;system development#GO:0048731;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell motility#GO:0048870;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neuron migration#GO:0001764;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell migration#GO:0016477;multicellular organismal process#GO:0032501;brain development#GO:0007420;cellular component assembly#GO:0022607;head development#GO:0060322;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;cell junction#GO:0030054;microtubule cytoskeleton#GO:0015630;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;intracellular membraneless organelle#GO:0043232;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000008623.1|UniProtKB=W5MQ29 W5MQ29 PTHR12011:SF348 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E5 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010143.1|UniProtKB=W5MVK4 W5MVK4 PTHR13276:SF0 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytosol#GO:0005829 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000006755.1|UniProtKB=W5MIF7 W5MIF7 PTHR11473:SF23 AROMATIC AMINO ACID HYDROXYLASE TRYPTOPHAN 5-HYDROXYLASE 1 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 serotonin metabolic process#GO:0042428;metabolic process#GO:0008152;biosynthetic process#GO:0009058;serotonin biosynthetic process#GO:0042427;phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;phenol-containing compound biosynthetic process#GO:0046189 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 5-Hydroxytryptamine biosynthesis#P04371>Tryptophan hydroxylase#P04399 LEPOC|Ensembl=ENSLOCG00000001882.1|UniProtKB=W5M1C1 W5M1C1 PTHR32008:SF2 MATURIN MATURIN regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of myeloid cell differentiation#GO:0045639;regulation of hemopoiesis#GO:1903706;regulation of signaling#GO:0023051;regulation of myeloid cell differentiation#GO:0045637;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007871.1|UniProtKB=W5MME8 W5MME8 PTHR11532:SF92 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE E metallopeptidase activity#GO:0008237;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 Vasopressin synthesis#P04395>Exopeptidase#P04592;CCKR signaling map#P06959>Carboxypeptidase E#P07026 LEPOC|Ensembl=ENSLOCG00000007260.1|UniProtKB=W5MK74 W5MK74 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED binding#GO:0005488;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002542.1|UniProtKB=W5M3R8 W5M3R8 PTHR19229:SF98 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA3 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810;localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000007134.1|UniProtKB=W5MJS9 W5MJS9 PTHR12674:SF2 PREFOLDIN SUBUNIT 5 PREFOLDIN SUBUNIT 5 cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000018112.1|UniProtKB=W5NNK4 W5NNK4 PTHR17045:SF7 MELANOCYTE SPECIFIC GENE RELATED CITED CBP_P300-INTERACTING TRANSACTIVATOR 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 response to transforming growth factor beta#GO:0071559;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;response to hormone#GO:0009725;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000010630.1|UniProtKB=W5MXB6 W5MXB6 PTHR48092:SF7 KNIRPS-RELATED PROTEIN-RELATED STEROID HORMONE RECEPTOR ERR2 sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000015535.1|UniProtKB=W5NER2 W5NER2 PTHR45636:SF8 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;nervous system development#GO:0007399;head development#GO:0060322;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000006225.1|UniProtKB=W5MGL2 W5MGL2 PTHR11963:SF4 LEUCINE AMINOPEPTIDASE-RELATED AMINOPEPTIDASE NPEPL1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007407.1|UniProtKB=W5MKT1 W5MKT1 PTHR24072:SF262 RHO FAMILY GTPASE CELL DIVISION CONTROL PROTEIN 42 HOMOLOG hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787 signaling#GO:0023052;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cell communication#GO:0007154;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;actin filament organization#GO:0007015;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208;G-protein#PC00020 Ras Pathway#P04393>Cdc42#P04569 LEPOC|Ensembl=ENSLOCG00000016356.1|UniProtKB=W5NHT7 W5NHT7 PTHR43671:SF115 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK2 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 organelle organization#GO:0006996;cell cycle G2/M phase transition#GO:0044839;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cell cycle#GO:0007049;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;mitotic cell cycle phase transition#GO:0044772;microtubule cytoskeleton organization#GO:0000226 microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013830.1|UniProtKB=W5N8U6 W5N8U6 PTHR24103:SF668 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF CONTAINING 65 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014982.1|UniProtKB=W5NCT5 W5NCT5 PTHR24243:SF227 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008539.1|UniProtKB=W5MPT1 W5MPT1 PTHR10900:SF12 PERIOSTIN-RELATED PERIOSTIN binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cell adhesion#GO:0007155;homophilic cell-cell adhesion#GO:0007156;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular process#GO:0009987 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000013464.1|UniProtKB=W5N7J7 W5N7J7 PTHR24056:SF241 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 2 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000008522.1|UniProtKB=W5MPQ7 W5MPQ7 PTHR10159:SF540 DUAL SPECIFICITY PROTEIN PHOSPHATASE RHODANESE DOMAIN-CONTAINING DUAL SPECIFICITY PROTEIN PHOSPHATASE-RELATED phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000012156.1|UniProtKB=W5N2U0 W5N2U0 PTHR24339:SF66 HOMEOBOX PROTEIN EMX-RELATED EMPTY SPIRACLES HOMEOBOX 3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;head development#GO:0060322 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009426.1|UniProtKB=W5MSZ2 W5MSZ2 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 LEPOC|Ensembl=ENSLOCG00000007714.1|UniProtKB=W5MLV8 W5MLV8 PTHR13153:SF5 CGTHBA PROTEIN -14 GENE PROTEIN GATOR1 COMPLEX PROTEIN NPRL3 regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;negative regulation of TORC1 signaling#GO:1904262;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;response to stimulus#GO:0050896 protein-containing complex#GO:0032991;Seh1-associated complex#GO:0035859 LEPOC|Ensembl=ENSLOCG00000007272.1|UniProtKB=W5MK93 W5MK93 PTHR15564:SF10 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of mitotic cell cycle#GO:0007346;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cell cycle#GO:0051726;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;generation of neurons#GO:0048699;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;nervous system development#GO:0007399;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;negative regulation of cell cycle#GO:0045786 plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425 LEPOC|Ensembl=ENSLOCG00000003773.1|UniProtKB=W5M815 W5M815 PTHR15138:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Huntington disease#P00029>TAFII130#P00806;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 LEPOC|Ensembl=ENSLOCG00000008333.1|UniProtKB=W5MP14 W5MP14 PTHR47708:SF2 FAMILY NOT NAMED SI:CH73-132F6.5 LEPOC|Ensembl=ENSLOCG00000016556.1|UniProtKB=W5NII9 W5NII9 PTHR46878:SF1 FORKHEAD BOX PROTEIN M1 FORKHEAD BOX PROTEIN M1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;regulation of DNA metabolic process#GO:0051052;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA metabolic process#GO:0051054;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of double-strand break repair#GO:2000781;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of double-strand break repair#GO:2000779;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA repair#GO:0045739;regulation of response to stress#GO:0080134;DNA damage response#GO:0006974;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016748.1|UniProtKB=W5NJ93 W5NJ93 PTHR10088:SF4 GLUCOKINASE REGULATORY PROTEIN GLUCOKINASE REGULATORY PROTEIN enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;kinase inhibitor activity#GO:0019210;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;carbohydrate derivative binding#GO:0097367;enzyme inhibitor activity#GO:0004857 homeostatic process#GO:0042592;protein localization to organelle#GO:0033365;carbohydrate homeostasis#GO:0033500;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;cellular homeostasis#GO:0019725;glucose homeostasis#GO:0042593;intracellular chemical homeostasis#GO:0055082;intracellular glucose homeostasis#GO:0001678;intracellular protein localization#GO:0008104;localization#GO:0051179;chemical homeostasis#GO:0048878 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000004237.1|UniProtKB=W5M9K8 W5M9K8 PTHR34769:SF1 RCG42593, ISOFORM CRA_A DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 LEPOC|Ensembl=ENSLOCG00000013727.1|UniProtKB=W5N8I5 W5N8I5 PTHR11972:SF208 NADPH OXIDASE NAD(P)H OXIDASE (H2O2-FORMING) oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to stress#GO:0006950;cellular process#GO:0009987;response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801;defense response#GO:0006952 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000009183.1|UniProtKB=W5MS43 W5MS43 PTHR22829:SF18 DEP DOMAIN PROTEIN DEP DOMAIN-CONTAINING MTOR-INTERACTING PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function activator activity#GO:0140677;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;enzyme activator activity#GO:0008047;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;kinase inhibitor activity#GO:0019210 response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000007277.1|UniProtKB=W5MKA0 W5MKA0 PTHR12002:SF6 CLAUDIN CLAUDIN-11 cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cell adhesion#GO:0007155;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular process#GO:0009987 plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000004161.1|UniProtKB=W5M9B4 W5M9B4 PTHR13050:SF7 USE1-LIKE PROTEIN VESICLE TRANSPORT PROTEIN USE1 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;membrane#GO:0016020;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000001785.1|UniProtKB=W5M112 W5M112 PTHR32073:SF8 GH11358P DIVERGENT PROTEIN KINASE DOMAIN 2B LEPOC|Ensembl=ENSLOCG00000014433.1|UniProtKB=W5NAV8 W5NAV8 PTHR12635:SF13 RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER RHO GTPASE-ACTIVATING PROTEIN 36 ISOFORM X1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000011371.1|UniProtKB=W5N014 W5N014 PTHR47695:SF5 PID DOMAIN-CONTAINING PROTEIN DISABLED HOMOLOG 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;negative regulation of cellular process#GO:0048523;positive regulation of developmental process#GO:0051094;transport#GO:0006810;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;positive regulation of endocytosis#GO:0045807;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;import into cell#GO:0098657;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100;positive regulation of cell differentiation#GO:0045597;vesicle-mediated transport#GO:0016192;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;endocytosis#GO:0006897;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;clathrin-coated pit#GO:0005905 LEPOC|Ensembl=ENSLOCG00000008757.1|UniProtKB=W5MQL3 W5MQL3 PTHR24293:SF0 CYTOCHROME P450 FAMILY 46 SUBFAMILY A CHOLESTEROL 24-HYDROXYLASE-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;tetrapyrrole binding#GO:0046906;binding#GO:0005488 primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid catabolic process#GO:0016042;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;steroid metabolic process#GO:0008202;secondary alcohol metabolic process#GO:1902652;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125;steroid catabolic process#GO:0006706 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000015969.1|UniProtKB=W5NGA5 W5NGA5 PTHR31503:SF10 VACUOLAR CALCIUM ION TRANSPORTER VNX1 PROTEIN metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013927.1|UniProtKB=W5N961 W5N961 PTHR17604:SF1 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011514.1|UniProtKB=W5N0I7 W5N0I7 PTHR13703:SF36 SMAD SMAD FAMILY MEMBER 5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987 cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;cellular response to growth factor stimulus#GO:0071363;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;BMP signaling pathway#GO:0030509;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;response to transforming growth factor beta#GO:0071559;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292;Wnt signaling pathway#P00057>Smad4#P01455 LEPOC|Ensembl=ENSLOCG00000016585.1|UniProtKB=W5NIM5 W5NIM5 PTHR13633:SF3 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000003014.1|UniProtKB=W5M587 W5M587 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000013503.1|UniProtKB=W5N7P9 W5N7P9 PTHR23169:SF7 ENVOPLAKIN ENVOPLAKIN cellular component organization or biogenesis#GO:0071840;wound healing#GO:0042060;intermediate filament-based process#GO:0045103;intermediate filament cytoskeleton organization#GO:0045104;response to stimulus#GO:0050896;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;response to stress#GO:0006950;cellular component organization#GO:0016043;response to wounding#GO:0009611;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000000108.1|UniProtKB=W5LVG0 W5LVG0 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001953.1|UniProtKB=W5M1J6 W5M1J6 PTHR12137:SF7 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 8 catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000002919.1|UniProtKB=W5M4X0 W5M4X0 PTHR18860:SF158 14-3-3 PROTEIN 14-3-3 PROTEIN GAMMA-1 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;Parkinson disease#P00049>14-3-3#P01238 LEPOC|Ensembl=ENSLOCG00000013439.1|UniProtKB=W5N7G8 W5N7G8 PTHR11481:SF67 IMMUNOGLOBULIN FC RECEPTOR PROTEIN IL-40 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;immune response#GO:0006955;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;immune system process#GO:0002376;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005863.1|UniProtKB=W5MFE1 W5MFE1 PTHR19367:SF18 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 18 immune response#GO:0006955;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012102.1|UniProtKB=W5N2P3 W5N2P3 PTHR10048:SF30 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT BETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 phosphatidylinositol phosphate biosynthetic process#GO:0046854;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;cell motility#GO:0048870;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;organophosphate metabolic process#GO:0019637;intracellular signaling cassette#GO:0141124;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 Angiogenesis#P00005>PI3K#P00236;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;EGF receptor signaling pathway#P00018>PI3K#P00557;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;p53 pathway feedback loops 2#P04398>PI3K#P04661;FGF signaling pathway#P00021>PI3K#P00640;Integrin signalling pathway#P00034>PI3K#P00936;VEGF signaling pathway#P00056>PI3K#P01413;Axon guidance mediated by netrin#P00009>PI3K#P00363 LEPOC|Ensembl=ENSLOCG00000000374.1|UniProtKB=W5LW98 W5LW98 PTHR46791:SF13 EXPRESSED PROTEIN INTEGRASE CORE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000476.1|UniProtKB=W5LWL5 W5LWL5 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015091.1|UniProtKB=W5ND66 W5ND66 PTHR13318:SF254 PARTNER OF PAIRED, ISOFORM B-RELATED PROTEIN AMN1 HOMOLOG catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 transferase complex#GO:1990234;catalytic complex#GO:1902494;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 LEPOC|Ensembl=ENSLOCG00000008173.1|UniProtKB=W5MNG2 W5MNG2 PTHR10411:SF4 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 p53 pathway#P00059>GADD45#G01575;p53 pathway#P00059>GADD45#P04626 LEPOC|Ensembl=ENSLOCG00000003643.1|UniProtKB=W5M7H3 W5M7H3 PTHR14949:SF59 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 7 ISOFORM X1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;blood vessel morphogenesis#GO:0048514;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;tube development#GO:0035295;vasculogenesis#GO:0001570;multicellular organismal process#GO:0032501;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007037.1|UniProtKB=W5MJG0 W5MJG0 PTHR20766:SF2 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4-LIKE ISOFORM X1 LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008103.1|UniProtKB=W5MN81 W5MN81 PTHR45939:SF5 PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED PEROXISOMAL MEMBRANE PROTEIN PMP34 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000011367.1|UniProtKB=W5N011 W5N011 PTHR22978:SF29 B-CELL TRANSLOCATION GENE PROTEIN BTG2 regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;negative regulation of cellular process#GO:0048523;negative regulation of cell population proliferation#GO:0008285;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000008314.1|UniProtKB=W5MNZ1 W5MNZ1 PTHR10006:SF20 MUCIN-1-RELATED CALCINEURIN-INTERACTING PROTEIN 2 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016869.1|UniProtKB=W5NJQ0 W5NJQ0 PTHR10983:SF73 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE EPSILON transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009362.1|UniProtKB=W5MSR1 W5MSR1 PTHR22647:SF2 SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2 regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012090.1|UniProtKB=W5N2M1 W5N2M1 PTHR23049:SF8 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN LIGHT CHAIN 5 myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003740.1|UniProtKB=W5M7V2 W5M7V2 PTHR10621:SF28 UV EXCISION REPAIR PROTEIN RAD23 UV EXCISION REPAIR PROTEIN RAD23 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;ubiquitin binding#GO:0043130 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000005251.1|UniProtKB=W5MD63 W5MD63 PTHR47620:SF1 CHROMOSOME 2 OPEN READING FRAME 66 GENE, 34066-RELATED LEPOC|Ensembl=ENSLOCG00000015515.1|UniProtKB=W5NEN7 W5NEN7 PTHR48071:SF18 SRCR DOMAIN-CONTAINING PROTEIN SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN DMBT1 ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000008313.1|UniProtKB=W5MNZ0 W5MNZ0 PTHR12370:SF3 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE AMINOPEPTIDASE PLBD2-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000012915.1|UniProtKB=W5N5K1 W5N5K1 PTHR11347:SF32 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1C phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell body#GO:0044297 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000013536.1|UniProtKB=W5N7T0 W5N7T0 PTHR11523:SF26 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-2 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671 inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;export from cell#GO:0140352;homeostatic process#GO:0042592;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000005799.1|UniProtKB=W5MF48 W5MF48 PTHR11219:SF9 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-4 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;synaptic membrane adhesion#GO:0099560;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;synapse organization#GO:0050808;anatomical structure development#GO:0048856;system development#GO:0048731;cell junction organization#GO:0034330;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000012914.1|UniProtKB=W5N5J8 W5N5J8 PTHR12858:SF2 RIBOSOME BIOGENESIS PROTEIN RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000012998.1|UniProtKB=W5N5V8 W5N5V8 PTHR43107:SF30 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN-FATTY-ACID--COA LIGASE transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;monocarboxylic acid transmembrane transporter activity#GO:0008028;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular process#GO:0009987;macromolecule localization#GO:0033036;long-chain fatty acid metabolic process#GO:0001676;lipid transport#GO:0006869;lipid metabolic process#GO:0006629;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;import into cell#GO:0098657;establishment of localization#GO:0051234;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000010449.1|UniProtKB=W5MWQ1 W5MWQ1 PTHR24418:SF227 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FER protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of immune response#GO:0050776;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;chemotaxis#GO:0006935;cell adhesion#GO:0007155;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;locomotion#GO:0040011;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;taxis#GO:0042330;response to chemical#GO:0042221;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Fer#P00469 LEPOC|Ensembl=ENSLOCG00000011688.1|UniProtKB=W5N154 W5N154 PTHR24413:SF97 SPECKLE-TYPE POZ PROTEIN SPECKLE-TYPE POZ PROTEIN protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010785.1|UniProtKB=W5MXW4 W5MXW4 PTHR43016:SF18 PRESEQUENCE PROTEASE PRESEQUENCE PROTEASE, MITOCHONDRIAL metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000003788.1|UniProtKB=W5M816 W5M816 PTHR11977:SF33 VILLIN ADVILLIN phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546 regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;actin filament-based process#GO:0030029;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000005477.1|UniProtKB=W5MDZ8 W5MDZ8 PTHR11076:SF33 DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER DNA POLYMERASE KAPPA DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097 response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000009068.1|UniProtKB=W5MRN8 W5MRN8 PTHR47140:SF1 MAP3K7 C-TERMINAL-LIKE PROTEIN MAP3K7 C-TERMINAL-LIKE PROTEIN Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TAK#P01285;Ras Pathway#P04393>TAK#P04575 LEPOC|Ensembl=ENSLOCG00000009392.1|UniProtKB=W5MSU2 W5MSU2 PTHR11829:SF310 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN I3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009094.1|UniProtKB=W5MRS8 W5MRS8 PTHR23349:SF97 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BHLH DOMAIN-CONTAINING PROTEIN DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000008979.1|UniProtKB=W5MRD4 W5MRD4 FTSJ3 PTHR10920:SF13 RIBOSOMAL RNA METHYLTRANSFERASE PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3 RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;rRNA (guanine) methyltransferase activity#GO:0016435;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;O-methyltransferase activity#GO:0008171 RNA methylation#GO:0001510;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;methylation#GO:0032259;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000002059.1|UniProtKB=W5M1Y1 W5M1Y1 PTHR24256:SF581 TRYPTASE-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000008574.1|UniProtKB=W5MPX2 W5MPX2 PTHR45615:SF8 MYOSIN HEAVY CHAIN, NON-MUSCLE UNCONVENTIONAL MYOSIN-XVIIIB macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;actin binding#GO:0003779;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000004652.1|UniProtKB=W5MB28 W5MB28 PTHR13681:SF24 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED TUDOR DOMAIN-CONTAINING PROTEIN 3 chromatin-protein adaptor activity#GO:0140463;RNA binding#GO:0003723;histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;nucleic acid binding#GO:0003676 regulatory ncRNA-mediated heterochromatin formation#GO:0031048;siRNA-mediated heterochromatin formation#GO:0141194;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000003339.1|UniProtKB=W5M6D7 W5M6D7 PTHR13572:SF2 ENDO-ALPHA-1,2-MANNOSIDASE GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE-LIKE PROTEIN catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 LEPOC|Ensembl=ENSLOCG00000008163.1|UniProtKB=W5MNE7 W5MNE7 PTHR10411:SF4 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of MAPK cascade#GO:0043410;regulation of JNK cascade#GO:0046328;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 p53 pathway#P00059>GADD45#G01575;p53 pathway#P00059>GADD45#P04626 LEPOC|Ensembl=ENSLOCG00000010001.1|UniProtKB=W5MV19 W5MV19 PTHR11960:SF66 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000002480.1|UniProtKB=W5M3F0 W5M3F0 PTHR12958:SF4 FRIEND OF GATA2-RELATED ZINC FINGER PROTEIN ZFPM1 transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;binding#GO:0005488;transcription regulator activity#GO:0140110;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;positive regulation of RNA metabolic process#GO:0051254;homeostasis of number of cells#GO:0048872;positive regulation of biosynthetic process#GO:0009891;erythrocyte differentiation#GO:0030218;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;hemopoiesis#GO:0030097;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organismal-level homeostasis#GO:0048871;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;myeloid cell differentiation#GO:0030099;negative regulation of metabolic process#GO:0009892;cell development#GO:0048468;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;heart development#GO:0007507;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;animal organ development#GO:0048513 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000001358.1|UniProtKB=W5LZI2 W5LZI2 PTHR46169:SF31 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A SIN3-HDAC COMPLEX-ASSOCIATED FACTOR,-LIKE-RELATED regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011871.1|UniProtKB=W5N1T7 W5N1T7 PTHR13820:SF4 SYNUCLEIN BETA-SYNUCLEIN transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;endocytosis#GO:0006897;signaling#GO:0023052;synaptic vesicle endocytosis#GO:0048488;chemical synaptic transmission#GO:0007268;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;localization#GO:0051179;cell communication#GO:0007154;cellular localization#GO:0051641;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808 axon#GO:0030424;intracellular anatomical structure#GO:0005622;cell body#GO:0044297;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection terminus#GO:0044306;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell junction#GO:0030054;axon terminus#GO:0043679;neuron projection#GO:0043005;presynapse#GO:0098793;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Parkinson disease#P00049>beta-Synuclein#P01217 LEPOC|Ensembl=ENSLOCG00000017173.1|UniProtKB=W5NKR7 W5NKR7 PTHR45725:SF7 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 2 regulation of nervous system development#GO:0051960;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of neurogenesis#GO:0050767;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;positive regulation of signal transduction#GO:0009967;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828 LEPOC|Ensembl=ENSLOCG00000006509.1|UniProtKB=W5MHL3 W5MHL3 PTHR24255:SF40 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED MBL ASSOCIATED SERINE PROTEASE 2 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000015076.1|UniProtKB=W5ND45 W5ND45 PTHR20875:SF2 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000000166.1|UniProtKB=W5LVM8 W5LVM8 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000000409.1|UniProtKB=W5LWD7 W5LWD7 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014446.1|UniProtKB=W5NAX1 W5NAX1 PTHR23202:SF117 WASP INTERACTING PROTEIN-RELATED ACTIN NUCLEATION-PROMOTING FACTOR WAS-RELATED small GTPase binding#GO:0031267;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012320.1|UniProtKB=W5N3H3 W5N3H3 PTHR43775:SF7 FATTY ACID SYNTHASE FATTY ACID SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000018043.1|UniProtKB=W5NND5 W5NND5 PTHR26451:SF866 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006763.1|UniProtKB=W5MII0 W5MII0 PTHR24025:SF1 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-2 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000011709.1|UniProtKB=W5N183 W5N183 PTHR31393:SF2 C5ORF31 SPERM-ASSOCIATED MICROTUBULE INNER PROTEIN 4 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000012923.1|UniProtKB=W5N5K2 W5N5K2 PTHR19282:SF261 TETRASPANIN TETRASPANIN-14 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013864.1|UniProtKB=W5N8Y8 W5N8Y8 PTHR48029:SF10 NUCLEOLAR PROTEIN 8 NUCLEOLAR PROTEIN 8 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000012364.1|UniProtKB=W5N3M8 W5N3M8 PTHR45746:SF2 LP21163P REGULATOR OF G PROTEIN SIGNALING 6 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;neuron projection#GO:0043005 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 LEPOC|Ensembl=ENSLOCG00000011959.1|UniProtKB=W5N246 W5N246 PTHR10075:SF4 BASIGIN RELATED EMBIGIN cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016823.1|UniProtKB=W5NJI7 W5NJI7 PTHR11203:SF11 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3 hydrolase activity#GO:0016787;RNA binding#GO:0003723;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;exonuclease activity#GO:0004527;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654 mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000013716.1|UniProtKB=W5N8F4 W5N8F4 PTHR23235:SF44 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 15 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000006436.1|UniProtKB=W5MHB4 W5MHB4 PTHR17601:SF3 RAFTLIN-RELATED RAFTLIN LEPOC|Ensembl=ENSLOCG00000004770.1|UniProtKB=W5MBI9 W5MBI9 PTHR32341:SF21 INTERFERON-INDUCIBLE GTPASE IRG-TYPE G DOMAIN-CONTAINING PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000017159.1|UniProtKB=W5NKP9 W5NKP9 PTHR33331:SF13 COILED-COIL DOMAIN-CONTAINING PROTEIN 162 COILED-COIL DOMAIN CONTAINING 162 LEPOC|Ensembl=ENSLOCG00000005440.1|UniProtKB=W5MDU4 W5MDU4 PTHR31833:SF2 UPF0690 PROTEIN C1ORF52 UPF0690 PROTEIN C1ORF52 LEPOC|Ensembl=ENSLOCG00000010157.1|UniProtKB=W5MVP3 W5MVP3 SUCLG2 PTHR11815:SF18 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 energy derivation by oxidation of organic compounds#GO:0015980;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000016897.1|UniProtKB=W5NJS7 W5NJS7 PTHR15141:SF49 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 TFIIS N-TERMINAL DOMAIN-CONTAINING PROTEIN nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000013255.1|UniProtKB=W5N6S0 W5N6S0 PTHR10846:SF61 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 5 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;antiporter activity#GO:0015297;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000010773.1|UniProtKB=W5MXU7 W5MXU7 PTHR10606:SF48 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;hydrolase activity, acting on ester bonds#GO:0016788;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;sugar-phosphatase activity#GO:0050308;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181;carbohydrate phosphatase#PC00066;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004651.1|UniProtKB=W5MB11 W5MB11 PTHR23048:SF3 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 1_3, SKELETAL MUSCLE ISOFORM structural molecule activity#GO:0005198;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;contractile muscle fiber#GO:0043292;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000004657.1|UniProtKB=W5MB16 W5MB16 PTHR24394:SF65 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 21 ISOFORM X1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008265.1|UniProtKB=W5MNS9 W5MNS9 PTHR45992:SF12 EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED EUKARYOTIC ELONGATION FACTOR 2 KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572 Oxidative stress response#P00046>eEF2K#P01127;p38 MAPK pathway#P05918>eEF2K#P06022 LEPOC|Ensembl=ENSLOCG00000002052.1|UniProtKB=W5M1X8 W5M1X8 PTHR12183:SF4 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 positive regulation of biological process#GO:0048518;regulation of protein stability#GO:0031647;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of developmental process#GO:0051094;protein stabilization#GO:0050821;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000016247.1|UniProtKB=W5NHC7 W5NHC7 PTHR22957:SF300 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 15 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000016315.1|UniProtKB=W5NHM8 W5NHM8 PTHR35678:SF1 PROTEIN STPG4 PROTEIN STPG4 chromatin binding#GO:0003682;binding#GO:0005488 biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000003998.1|UniProtKB=W5M8S5 W5M8S5 PTHR24349:SF114 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-INTERACTING SERINE_THREONINE-PROTEIN KINASE 1 protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Oxidative stress response#P00046>MNK1/2#P01137;Interleukin signaling pathway#P00036>MNK1/2#P00972;PDGF signaling pathway#P00047>MNK1/2#P01149;p38 MAPK pathway#P05918>MNK1#P06018 LEPOC|Ensembl=ENSLOCG00000001322.1|UniProtKB=W5LZE5 W5LZE5 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010618.1|UniProtKB=W5MX91 W5MX91 PTHR35667:SF1 LEUKEMIA NUP98 FUSION PARTNER 1 LEUKEMIA NUP98 FUSION PARTNER 1 LEPOC|Ensembl=ENSLOCG00000010942.1|UniProtKB=W5MYG2 W5MYG2 PTHR24333:SF13 HOMEO BOX HB9 LIKE A-RELATED HOMEOBOX DOMAIN-CONTAINING PROTEIN homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000013675.1|UniProtKB=W5N898 W5N898 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012909.1|UniProtKB=W5N5I9 W5N5I9 PTHR10799:SF964 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A CONTAINING DEAD_H BOX 1 catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;heterochromatin formation#GO:0031507;cellular response to stimulus#GO:0051716;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to stress#GO:0033554;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;double-strand break repair#GO:0006302;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009;DNA helicase#PC00011 LEPOC|Ensembl=ENSLOCG00000010563.1|UniProtKB=W5MX38 W5MX38 PTHR12241:SF164 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL5 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;binding#GO:0005488 developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017906.1|UniProtKB=W5NN00 W5NN00 PTHR24366:SF73 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT NEURONAL PROTEIN 3 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000003803.1|UniProtKB=W5M826 W5M826 PTHR12109:SF3 RING FINGER PROTEIN 141-RELATED RING FINGER PROTEIN 141 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 LEPOC|Ensembl=ENSLOCG00000013976.1|UniProtKB=W5N9B7 W5N9B7 PTHR12939:SF5 SARCOGLYCAN ZETA-SARCOGLYCAN multicellular organismal process#GO:0032501;tissue development#GO:0009888;blood circulation#GO:0008015;heart development#GO:0007507;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;animal organ development#GO:0048513;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;heart contraction#GO:0060047;system process#GO:0003008;heart process#GO:0003015;circulatory system development#GO:0072359;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;system development#GO:0048731 sarcolemma#GO:0042383;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000000335.1|UniProtKB=W5LWA2 W5LWA2 PTHR16675:SF191 MHC CLASS I-RELATED CLASS I HISTOCOMPATIBILITY ANTIGEN, GOGO-C*0202 ALPHA CHAIN-LIKE-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005458.1|UniProtKB=W5MDX8 W5MDX8 PTHR24044:SF411 NOTCH LIGAND FAMILY MEMBER SUSHI, NIDOGEN AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000000035.1|UniProtKB=W5LV87 W5LV87 PTHR24126:SF7 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009140.1|UniProtKB=W5MRZ5 W5MRZ5 PTHR47633:SF17 IMMUNOGLOBULIN OBSCURIN, CYTOSKELETAL CALMODULIN AND TITIN-INTERACTING RHOGEF A LEPOC|Ensembl=ENSLOCG00000000732.1|UniProtKB=W5LXF7 W5LXF7 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012602.1|UniProtKB=W5N4F9 W5N4F9 PTHR23116:SF29 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED PDZ DOMAIN-CONTAINING PROTEIN 7 system development#GO:0048731;anatomical structure development#GO:0048856;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;embryonic organ development#GO:0048568;animal organ morphogenesis#GO:0009887;system process#GO:0003008;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;sensory organ development#GO:0007423;epidermis development#GO:0008544;plasma membrane bounded cell projection organization#GO:0120036;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;inner ear development#GO:0048839;neuron development#GO:0048666;ear development#GO:0043583;generation of neurons#GO:0048699;nervous system process#GO:0050877;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;sensory perception of sound#GO:0007605;cell morphogenesis#GO:0000902;sensory organ morphogenesis#GO:0090596;anatomical structure morphogenesis#GO:0009653;inner ear receptor cell stereocilium organization#GO:0060122;cellular component organization#GO:0016043;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;embryo development#GO:0009790;cellular process#GO:0009987;inner ear morphogenesis#GO:0042472;neuron projection development#GO:0031175;hair cell differentiation#GO:0035315 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;stereocilium#GO:0032420;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000002394.1|UniProtKB=W5M350 W5M350 PTHR20959:SF1 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG export from cell#GO:0140352;macromolecule localization#GO:0033036;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;protein secretion#GO:0009306;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;transport#GO:0006810 LEPOC|Ensembl=ENSLOCG00000001817.1|UniProtKB=W5M142 W5M142 PTHR11042:SF59 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED SERINE_THREONINE-PROTEIN KINASE 35 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000006844.1|UniProtKB=W5MIR7 W5MIR7 PTHR23411:SF18 TAPASIN TAPASIN-RELATED PROTEIN binding#GO:0005488;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;antigen processing and presentation#GO:0019882;protein-containing complex organization#GO:0043933;immune system process#GO:0002376;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005587.1|UniProtKB=W5MED7 W5MED7 PTHR11510:SF5 MYO-INOSITOL-1 PHOSPHATE SYNTHASE INOSITOL-3-PHOSPHATE SYNTHASE 1 catalytic activity#GO:0003824;isomerase activity#GO:0016853 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283;alcohol biosynthetic process#GO:0046165;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 isomerase#PC00135 LEPOC|Ensembl=ENSLOCG00000006464.1|UniProtKB=W5MHF2 W5MHF2 PTHR22917:SF9 HEMOPEXIN DOMAIN-CONTAINING PROTEIN HEMOPEXIN cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000010028.1|UniProtKB=W5MV49 W5MV49 PTHR11477:SF7 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A N-TERMINAL AND CENTRAL DOMAIN-CONTAINING PROTEIN transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000008754.1|UniProtKB=W5MQJ7 W5MQJ7 PTHR14955:SF6 RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 20 RETINOIC ACID-INDUCED PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000009458.1|UniProtKB=W5MT50 W5MT50 PTHR23421:SF50 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE-1-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 galactosidase#PC00104;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011377.1|UniProtKB=W5N031 W5N031 PTHR45742:SF3 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C9 immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;humoral immune response#GO:0006959;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778;positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;immune response#GO:0006955;activation of immune response#GO:0002253;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007 extracellular region#GO:0005576;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000000063.1|UniProtKB=W5LVB6 W5LVB6 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006051.1|UniProtKB=W5MG02 W5MG02 PTHR10869:SF223 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-3 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213 endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011283.1|UniProtKB=W5MZR1 W5MZR1 PTHR28384:SF1 PROGRESSIVE ANKYLOSIS PROTEIN HOMOLOG MINERALIZATION REGULATOR ANKH transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;phosphate transmembrane transporter activity#GO:0005315;active transmembrane transporter activity#GO:0022804 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000004768.1|UniProtKB=W5MBG5 W5MBG5 PTHR46514:SF1 AMPHIPHYSIN BRIDGING INTEGRATOR 2 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 protein-containing complex organization#GO:0043933;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;membrane invagination#GO:0010324;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;phagocytosis#GO:0006909;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;localization#GO:0051179;plasma membrane organization#GO:0007009;cell projection organization#GO:0030030;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000007536.1|UniProtKB=W5ML82 W5ML82 PTHR45877:SF7 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SIAH1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Wnt signaling pathway#P00057>SIAH-1#P01433;p53 pathway#P00059>Siah#G04696;p53 pathway feedback loops 2#P04398>SIAH-1#P04660;p53 pathway feedback loops 2#P04398>SIAH-1#G04711 LEPOC|Ensembl=ENSLOCG00000001400.1|UniProtKB=W5LZN8 W5LZN8 PTHR22776:SF10 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 8 signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012079.1|UniProtKB=W5N2K0 W5N2K0 PTHR21493:SF245 CGI-141-RELATED/LIPASE CONTAINING PROTEIN VESICLE TRANSPORT PROTEIN GOT1A membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003249.1|UniProtKB=W5M627 W5M627 PTHR24260:SF149 AT07769P-RELATED AT07769P-RELATED LEPOC|Ensembl=ENSLOCG00000015094.1|UniProtKB=W5ND70 W5ND70 PTHR23509:SF7 PA-PL1 PHOSPHOLIPASE FAMILY TRIACYLGLYCEROL HYDROLASE DDHD2 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;triacylglycerol lipase activity#GO:0004806 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229 phospholipase#PC00186;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013570.1|UniProtKB=W5N7Y0 W5N7Y0 PTHR10048:SF95 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 glycerophospholipid metabolic process#GO:0006650;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;biological regulation#GO:0065007;biosynthetic process#GO:0009058;intracellular signaling cassette#GO:0141124;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;cell motility#GO:0048870;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556;phosphatidylinositol phosphate biosynthetic process#GO:0046854 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000009642.1|UniProtKB=W5MTS5 W5MTS5 PTHR13798:SF12 RNA BINDING MOTIF RBM PROTEIN -RELATED RNA BINDING MOTIF PROTEIN 11-RELATED RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012825.1|UniProtKB=W5N578 W5N578 PTHR45636:SF20 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-5 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000001224.1|UniProtKB=W5LZ31 W5LZ31 PTHR46799:SF1 HOMEOBOX PROTEIN UNC-4 HOMOLOG HOMEOBOX PROTEIN UNC-4 HOMOLOG sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000010513.1|UniProtKB=W5MWZ2 W5MWZ2 PTHR19961:SF35 FIMBRIN/PLASTIN PLASTIN-2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090 actin filament bundle assembly#GO:0051017;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000011581.1|UniProtKB=W5N0T2 W5N0T2 PTHR45673:SF7 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT BETA ISOFORM hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;binding#GO:0005488;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;calcineurin-mediated signaling#GO:0097720;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 protein phosphatase#PC00195 Wnt signaling pathway#P00057>Calcineurin#P01446;T cell activation#P00053>Calcineurin#P01315;B cell activation#P00010>Calcineurin#P00386 LEPOC|Ensembl=ENSLOCG00000012474.1|UniProtKB=W5N420 W5N420 PTHR10199:SF122 THROMBOSPONDIN THROMBOSPONDIN-1 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell population proliferation#GO:0008285;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000909.1|UniProtKB=W5LY11 W5LY11 PTHR15180:SF1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;rRNA transcription#GO:0009303;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 transcription factor TFIIIC complex#GO:0000127;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000017358.1|UniProtKB=W5NLF4 W5NLF4 PTHR33663:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 177 COILED-COIL DOMAIN-CONTAINING PROTEIN 185 LEPOC|Ensembl=ENSLOCG00000003508.1|UniProtKB=W5M6Z8 W5M6Z8 PTHR11516:SF60 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;nucleoside phosphate metabolic process#GO:0006753;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333 mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;membrane-enclosed lumen#GO:0031974;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234 dehydrogenase#PC00092;oxidoreductase#PC00176 Pyruvate metabolism#P02772>Pyruvate Dehydrogenase#P03133 LEPOC|Ensembl=ENSLOCG00000004415.1|UniProtKB=W5MA67 W5MA67 PTHR19980:SF0 RNA CLEAVAGE STIMULATION FACTOR CLEAVAGE STIMULATION FACTOR SUBUNIT 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000009926.1|UniProtKB=W5MUS6 W5MUS6 PTHR19446:SF482 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000014221.1|UniProtKB=W5NA55 W5NA55 PTHR22804:SF40 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 3 multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 extracellular region#GO:0005576;cell junction#GO:0030054;membrane#GO:0016020;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000015821.1|UniProtKB=W5NFR7 W5NFR7 PTHR10151:SF125 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 5 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009483.1|UniProtKB=W5MT72 W5MT72 PTHR23504:SF77 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 SOLUTE CARRIER FAMILY 71 MEMBER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 multicellular organismal reproductive process#GO:0048609;system process#GO:0003008;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;gamete generation#GO:0007276;male gamete generation#GO:0048232;developmental process involved in reproduction#GO:0003006 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000005770.1|UniProtKB=W5MF18 W5MF18 PTHR10337:SF5 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Shc#P00554;Angiogenesis#P00005>Sck#P00202;PDGF signaling pathway#P00047>Shc#P01175;VEGF signaling pathway#P00056>Sck#P01424 LEPOC|Ensembl=ENSLOCG00000004457.1|UniProtKB=W5MAC5 W5MAC5 PTHR48109:SF4 DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;pyrimidine nucleobase metabolic process#GO:0006206;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide metabolic process#GO:0009259;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydrooratate oxidase#P02927 LEPOC|Ensembl=ENSLOCG00000013543.1|UniProtKB=W5N7T5 W5N7T5 PTHR10219:SF19 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN DOMAIN-CONTAINING PROTEIN 2 phospholipid binding#GO:0005543;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;lipid carrier activity#GO:0005319;ion binding#GO:0043167;molecular carrier activity#GO:0140104;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 ceramide transport#GO:0035627;membrane organization#GO:0061024;lipid transport#GO:0006869;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;lipid localization#GO:0010876 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014398.1|UniProtKB=W5NAR6 W5NAR6 PTHR22734:SF2 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 binding#GO:0005488;rRNA binding#GO:0019843;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000007410.1|UniProtKB=W5MKT8 W5MKT8 PTHR23092:SF51 POLY(A) RNA POLYMERASE TERMINAL NUCLEOTIDYLTRANSFERASE 4B transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 RNA metabolic process#GO:0016070;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000017640.1|UniProtKB=W5NM86 W5NM86 PTHR22639:SF13 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3-LIKE viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000014109.1|UniProtKB=W5N9S3 W5N9S3 PTHR21771:SF0 MITOCHONDRIA-EATING PROTEIN-RELATED MITOCHONDRIA-EATING PROTEIN molecular condensate scaffold activity#GO:0140693;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 mitochondrion organization#GO:0007005;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organelle organization#GO:0006996;process utilizing autophagic mechanism#GO:0061919;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein catabolic process#GO:0030163;autophagy of mitochondrion#GO:0000422;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 organelle envelope#GO:0031967;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;outer membrane#GO:0019867;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000012494.1|UniProtKB=W5N435 W5N435 PTHR10953:SF186 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 6 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000007610.1|UniProtKB=W5MLH4 W5MLH4 PTHR19969:SF16 SH2-SH3 ADAPTOR PROTEIN-RELATED SH2_SH3 ADAPTER PROTEIN NCK1 binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971 regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;positive regulation of signal transduction#GO:0009967;regulation of intrinsic apoptotic signaling pathway#GO:2001242;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;response to endoplasmic reticulum stress#GO:0034976;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of translation#GO:0045727;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of signaling#GO:0023056;regulation of cellular response to stress#GO:0080135;negative regulation of cell communication#GO:0010648 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 T cell activation#P00053>nck#P01314;PDGF signaling pathway#P00047>Grb2#P01148;Angiogenesis#P00005>Nck#P00215;PDGF signaling pathway#P00047>Nck#P01147 LEPOC|Ensembl=ENSLOCG00000013696.1|UniProtKB=W5N8C7 W5N8C7 PTHR19871:SF43 BETA TRANSDUCIN-RELATED PROTEIN SI:CH211-212K18.6 LEPOC|Ensembl=ENSLOCG00000016347.1|UniProtKB=W5NHS7 W5NHS7 PTHR12062:SF14 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE C transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007117.1|UniProtKB=W5MJQ9 W5MJQ9 PTHR12459:SF27 TRANSMEMBRANE PROTEIN 135-RELATED TRANSMEMBRANE PROTEIN 135 LEPOC|Ensembl=ENSLOCG00000002225.1|UniProtKB=W5M2I3 W5M2I3 PTHR24115:SF889 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF27 microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000005013.1|UniProtKB=W5MCE6 W5MCE6 PTHR12845:SF3 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 16 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of actin filament-based process#GO:0032970;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin cytoskeleton organization#GO:0032956;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000015372.1|UniProtKB=W5NE57 W5NE57 PTHR31395:SF11 SHISA PROTEIN SHISA-LIKE-1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001909.1|UniProtKB=W5M1F6 W5M1F6 PTHR10758:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 COP9 SIGNALOSOME COMPLEX SUBUNIT 3 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006514.1|UniProtKB=W5MHK5 W5MHK5 PTHR36872:SF1 GENE 5901-RELATED GENE 5901-RELATED 9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014956.1|UniProtKB=W5NCQ6 W5NCQ6 PTHR23235:SF46 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 8 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000016253.1|UniProtKB=W5NHD3 W5NHD3 PTHR18842:SF2 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000005352.1|UniProtKB=W5MDJ6 W5MDJ6 PTHR11049:SF3 ACYL COENZYME A THIOESTER HYDROLASE ACETYL-COENZYME A THIOESTERASE hydrolase activity#GO:0016787;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;acetyl-CoA metabolic process#GO:0006084;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000008930.1|UniProtKB=W5MR66 W5MR66 PTHR22894:SF2 RING-TYPE DOMAIN-CONTAINING PROTEIN RING-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017266.1|UniProtKB=W5NL47 W5NL47 PTHR19307:SF8 TUMOR PROTEIN D52 TUMOR PROTEIN D53 cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;positive regulation of biological process#GO:0048518;regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408;regulation of JNK cascade#GO:0046328;positive regulation of apoptotic process#GO:0043065;regulation of programmed cell death#GO:0043067;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;mitotic cell cycle process#GO:1903047;positive regulation of signal transduction#GO:0009967;cell cycle#GO:0007049;G2/M transition of mitotic cell cycle#GO:0000086;positive regulation of cell communication#GO:0010647;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;mitotic cell cycle phase transition#GO:0044772;regulation of apoptotic signaling pathway#GO:2001233 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003923.1|UniProtKB=W5M8I1 W5M8I1 PTHR10543:SF86 BETA-CAROTENE DIOXYGENASE BETA,BETA-CAROTENE 15,15'-DIOXYGENASE dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;primary metabolic process#GO:0044238;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000005989.1|UniProtKB=W5MFS9 W5MFS9 PTHR12442:SF26 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 2 binding#GO:0005488;protein binding#GO:0005515 transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;dynein complex#GO:0030286;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000003800.1|UniProtKB=W5M825 W5M825 PTHR24078:SF288 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 4 protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 metabolic process#GO:0008152;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;protein maturation#GO:0051604;gene expression#GO:0010467;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;protein folding#GO:0006457;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000506.1|UniProtKB=W5LWP9 W5LWP9 PTHR23198:SF26 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN NUP96 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002995.1|UniProtKB=W5M570 W5M570 PTHR12155:SF29 SCHLAFEN SCHLAFEN-LIKE PROTEIN 1 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000017209.1|UniProtKB=W5NKW7 W5NKW7 PTHR12045:SF3 ALLANTOICASE INACTIVE ALLANTOICASE-RELATED Allantoin degradation#P02725>Allantoate amidohydrolase#P02821 LEPOC|Ensembl=ENSLOCG00000006912.1|UniProtKB=W5MIZ9 W5MIZ9 PTHR12300:SF39 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 3 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum tubular network organization#GO:0071786 organelle membrane#GO:0031090;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;endoplasmic reticulum tubular network#GO:0071782;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;cytoplasmic microtubule#GO:0005881 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015100.1|UniProtKB=W5ND76 W5ND76 PTHR14336:SF5 TANDEM PH DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 2 small molecule binding#GO:0036094;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488;ion binding#GO:0043167;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000010578.1|UniProtKB=W5MX51 W5MX51 PTHR11685:SF371 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF14 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007446.1|UniProtKB=W5MKY1 W5MKY1 PTHR10807:SF66 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein phosphatase binding#GO:0019903;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;phosphoric ester hydrolase activity#GO:0042578;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;protein binding#GO:0005515;hydrolase activity#GO:0016787 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;dephosphorylation#GO:0016311;lipid modification#GO:0030258 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000013598.1|UniProtKB=W5N813 W5N813 PTHR11610:SF2 LIPASE HEPATIC TRIACYLGLYCEROL LIPASE protein binding#GO:0005515;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;binding#GO:0005488;lipase activity#GO:0016298;catalytic activity#GO:0003824 catabolic process#GO:0009056;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 Triacylglycerol metabolism#P02782>Triacylglycerol lipase#P03205 LEPOC|Ensembl=ENSLOCG00000003973.1|UniProtKB=W5M8P0 W5M8P0 PTHR10285:SF222 URIDINE KINASE MIBP PROTEIN-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000008011.1|UniProtKB=W5MMX4 W5MMX4 PTHR45161:SF2 CYTOSKELETON-ASSOCIATED PROTEIN 4 RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 2 LEPOC|Ensembl=ENSLOCG00000015014.1|UniProtKB=W5NCX4 W5NCX4 PTHR23087:SF10 NONHISTONE CHROMOSOMAL PROTEIN HMG HIGH MOBILITY GROUP NUCLEOSOMAL BINDING DOMAIN 7 ISOFORM X1-RELATED chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009758.1|UniProtKB=W5MU64 W5MU64 PTHR19868:SF0 RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1 SMALL RIBOSOMAL SUBUNIT PROTEIN RACK1 protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;negative regulation of translation#GO:0017148;negative regulation of metabolic process#GO:0009892;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;regulation of biological process#GO:0050789;rescue of stalled cytosolic ribosome#GO:0072344;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;translational elongation#GO:0006414;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;regulation of protein metabolic process#GO:0051246;protein metabolic process#GO:0019538;translation#GO:0006412;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000008123.1|UniProtKB=W5MNA9 W5MNA9 PTHR43995:SF1 PRE-MRNA-PROCESSING FACTOR 19 PRE-MRNA-PROCESSING FACTOR 19 ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cytoplasm#GO:0005737;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA processing factor#PC00147 mRNA splicing#P00058>U4#P01476 LEPOC|Ensembl=ENSLOCG00000014735.1|UniProtKB=W5NBY7 W5NBY7 PTHR24346:SF28 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MAP_MICROTUBULE AFFINITY-REGULATING KINASE 4 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000008493.1|UniProtKB=W5MPM9 W5MPM9 PTHR13060:SF0 SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2 PROTEIN ECDYSONELESS HOMOLOG transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000011340.1|UniProtKB=W5MZX6 W5MZX6 PTHR22883:SF11 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC21 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008378.1|UniProtKB=W5MP71 W5MP71 PTHR21557:SF2 CORDON-BLEU CORDON-BLEU PROTEIN-LIKE 1 LEPOC|Ensembl=ENSLOCG00000003669.1|UniProtKB=W5M7Q3 W5M7Q3 PTHR12844:SF21 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;postsynapse organization#GO:0099173;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;response to stimulus#GO:0050896;synapse organization#GO:0050808;postsynaptic specialization organization#GO:0099084;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013803.1|UniProtKB=W5N8R7 W5N8R7 PTHR11035:SF20 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 3 catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000017017.1|UniProtKB=W5NK76 W5NK76 PTHR10188:SF35 L-ASPARAGINASE ISOASPARTYL PEPTIDASE_L-ASPARAGINASE cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016829.1|UniProtKB=W5NJJ1 W5NJJ1 PTHR46708:SF8 TENASCIN FIBRONECTIN signaling receptor binding#GO:0005102;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877 cell-substrate junction assembly#GO:0007044;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;circulatory system development#GO:0072359;cell junction organization#GO:0034330;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;heart development#GO:0007507;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;developmental process#GO:0032502;cell-substrate junction organization#GO:0150115;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Fibronectin#P00939 LEPOC|Ensembl=ENSLOCG00000008915.1|UniProtKB=W5MR54 W5MR54 PTHR43435:SF4 RIBULOKINASE FGGY CARBOHYDRATE KINASE DOMAIN-CONTAINING PROTEIN phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200 small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137;carbohydrate kinase#PC00065;transferase#PC00220 Ascorbate degradation#P02729>L-xylulose kinase#P02849;Pentose phosphate pathway#P02762>D-Ribulo Kinase#P03077 LEPOC|Ensembl=ENSLOCG00000016900.1|UniProtKB=W5NJT1 W5NJT1 PTHR31514:SF1 MUSCULAR LMNA-INTERACTING PROTEIN MLIP MUSCULAR LMNA-INTERACTING PROTEIN LEPOC|Ensembl=ENSLOCG00000001517.1|UniProtKB=W5M022 W5M022 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013883.1|UniProtKB=W5N909 W5N909 PTHR12484:SF4 B-LYMPHOCYTE ANTIGEN-RELATED A-KINASE ANCHOR PROTEIN 17A LEPOC|Ensembl=ENSLOCG00000001834.1|UniProtKB=W5M177 W5M177 PTHR11473:SF45 AROMATIC AMINO ACID HYDROXYLASE TYROSINE 3-MONOOXYGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;reproductive process#GO:0022414;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;phenol-containing compound metabolic process#GO:0018958;catecholamine metabolic process#GO:0006584;cell communication#GO:0007154;multicellular organismal reproductive process#GO:0048609;trans-synaptic signaling#GO:0099537;cognition#GO:0050890;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;biogenic amine metabolic process#GO:0006576;cell-cell signaling#GO:0007267;biosynthetic process#GO:0009058;phenol-containing compound biosynthetic process#GO:0046189;amine metabolic process#GO:0009308;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, dopaminergic#GO:0001963;system process#GO:0003008;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;cell body#GO:0044297;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;perikaryon#GO:0043204;axon#GO:0030424 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006474.1|UniProtKB=W5MHG6 W5MHG6 PTHR11879:SF58 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 LEPOC|Ensembl=ENSLOCG00000006454.1|UniProtKB=W5MHD6 W5MHD6 PTHR48112:SF36 HIGH MOBILITY GROUP PROTEIN DSP1 TRANSCRIPTION FACTOR A, MITOCHONDRIAL transcription regulator activity#GO:0140110 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription initiation#GO:0006352;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nucleoid#GO:0009295;organelle#GO:0043226;mitochondrial nucleoid#GO:0042645;mitochondrion#GO:0005739;organelle lumen#GO:0043233 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000015512.1|UniProtKB=W5NEN4 W5NEN4 PTHR11735:SF14 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014634.1|UniProtKB=W5NBK3 W5NBK3 PTHR24034:SF175 EGF-LIKE DOMAIN-CONTAINING PROTEIN COLLAGEN AND CALCIUM-BINDING EGF DOMAIN-CONTAINING PROTEIN 1-LIKE anatomical structure morphogenesis#GO:0009653;multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000002622.1|UniProtKB=W5M3X7 W5M3X7 PTHR14470:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III DOMAIN CONTAINING 5 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000013973.1|UniProtKB=W5N9B5 W5N9B5 PTHR28593:SF5 METEORIN-LIKE PROTEIN METEORIN-LIKE PROTEIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 multicellular organismal process#GO:0032501;multicellular organismal-level homeostasis#GO:0048871;homeostatic process#GO:0042592 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006770.1|UniProtKB=W5MIJ3 W5MIJ3 PTHR11226:SF3 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 1 glucosyltransferase activity#GO:0046527;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000011250.1|UniProtKB=W5MZL0 W5MZL0 PTHR10656:SF30 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 3 nucleotidyltransferase#PC00174;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000014105.1|UniProtKB=W5N9S1 W5N9S1 PTHR15913:SF1 ACID CLUSTER PROTEIN 33 MASPARDIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network transport vesicle#GO:0030140;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798 LEPOC|Ensembl=ENSLOCG00000017831.1|UniProtKB=W5NMS5 W5NMS5 PTHR11214:SF402 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000017382.1|UniProtKB=W5NLH8 W5NLH8 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002714.1|UniProtKB=W5M480 W5M480 PTHR10250:SF19 MICROSOMAL GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL oxidoreductase activity#GO:0016491;transferase activity#GO:0016740;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;glutathione transferase activity#GO:0004364 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000003152.1|UniProtKB=W5M5R1 W5M5R1 PTHR13610:SF5 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN ADENINE NUCLEOTIDE TRANSLOCASE LYSINE N-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;lysine N-methyltransferase activity#GO:0016278 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007476.1|UniProtKB=W5ML13 W5ML13 PTHR24243:SF7 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007386.1|UniProtKB=W5MKR0 W5MKR0 PTHR45623:SF8 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD6 catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;histone binding#GO:0042393;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;hydrolase activity#GO:0016787;DNA binding#GO:0003677;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010539.1|UniProtKB=W5MX06 W5MX06 PTHR22984:SF34 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of mitotic cell cycle#GO:0007346;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000006291.1|UniProtKB=W5MGU0 W5MGU0 PTHR15901:SF16 TESTICULAR HAPLOID EXPRESSED GENE PROTEIN SPERM MICROTUBULE ASSOCIATED PROTEIN 2 reproductive process#GO:0022414;male gamete generation#GO:0048232;gamete generation#GO:0007276;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000003531.1|UniProtKB=W5M716 W5M716 PTHR45617:SF2 LEUCINE RICH REPEAT FAMILY PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003854.1|UniProtKB=W5M892 W5M892 PTHR11003:SF18 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 15 potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;potassium ion transport#GO:0006813;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012905.1|UniProtKB=W5N5J3 W5N5J3 PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;amidase activity#GO:0004040;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 LEPOC|Ensembl=ENSLOCG00000007239.1|UniProtKB=W5MK51 W5MK51 PTHR24391:SF17 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER E-BOX-BINDING HOMEOBOX 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#G06670;Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#G06884;Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#P06783 LEPOC|Ensembl=ENSLOCG00000000024.1|UniProtKB=W5LV71 W5LV71 PTHR43544:SF12 SHORT-CHAIN DEHYDROGENASE/REDUCTASE SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017343.1|UniProtKB=W5NLD9 W5NLD9 PTHR13205:SF15 TRANSMEMBRANE PROTEIN 15-RELATED DOLICHOL KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003436.1|UniProtKB=W5M6R7 W5M6R7 PTHR10751:SF100 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 1 ISOFORM X1-RELATED hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 G-protein#PC00020;heterotrimeric G-protein#PC00117 LEPOC|Ensembl=ENSLOCG00000012677.1|UniProtKB=W5N4Q5 W5N4Q5 PTHR10350:SF6 NUCLEAR PORE COMPLEX PROTEIN NUP155 NUCLEAR PORE COMPLEX PROTEIN NUP155 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cellular localization#GO:0051641;protein import into nucleus#GO:0006606;protein transport#GO:0015031;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;nucleobase-containing compound transport#GO:0015931;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;establishment of RNA localization#GO:0051236;localization within membrane#GO:0051668;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006254.1|UniProtKB=W5MGP7 W5MGP7 PTHR12144:SF0 NEGATIVE ELONGATION FACTOR D NEGATIVE ELONGATION FACTOR C_D RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000016328.1|UniProtKB=W5NHP6 W5NHP6 PTHR14454:SF5 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000005572.1|UniProtKB=W5MEB6 W5MEB6 PTHR46760:SF1 TRANSCRIPTION TERMINATION FACTOR 1 TRANSCRIPTION TERMINATION FACTOR 1 General transcription regulation#P00023>TTF2#P00661;General transcription by RNA polymerase I#P00022>TTF-I#P00654;Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 LEPOC|Ensembl=ENSLOCG00000007509.1|UniProtKB=W5ML75 W5ML75 PTHR23120:SF0 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 1 ISOFORM X1 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009163.1|UniProtKB=W5MS10 W5MS10 PTHR24340:SF28 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000002533.1|UniProtKB=W5M3L4 W5M3L4 PTHR46756:SF2 TRANSGELIN CALPONIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;actin filament-based process#GO:0030029;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;actin filament organization#GO:0007015;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;protein localization to microtubule cytoskeleton#GO:0072698;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036 microtubule end#GO:1990752;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432;microtubule#GO:0005874;actomyosin#GO:0042641;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;stress fiber#GO:0001725;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000017615.1|UniProtKB=W5NM61 W5NM61 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183-LIKE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010493.1|UniProtKB=W5MWV2 W5MWV2 PTHR31663:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 COILED-COIL DOMAIN-CONTAINING 3B LEPOC|Ensembl=ENSLOCG00000017279.1|UniProtKB=W5NL63 W5NL63 PTHR14963:SF6 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 18 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 regulation of biological quality#GO:0065008;regulation of signaling#GO:0023051;regulation of actin filament length#GO:0030832;regulation of intracellular signal transduction#GO:1902531;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;regulation of response to stimulus#GO:0048583;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000010621.1|UniProtKB=W5MX99 W5MX99 PTHR14195:SF3 G PATCH DOMAIN CONTAINING PROTEIN 2 G PATCH DOMAIN-CONTAINING PROTEIN 2-LIKE nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004926.1|UniProtKB=W5MC13 W5MC13 PTHR10496:SF0 40S RIBOSOMAL PROTEIN S24 40S RIBOSOMAL PROTEIN S24 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000003154.1|UniProtKB=W5M5R0 W5M5R0 PTHR45625:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3 catalytic activity#GO:0003824;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096 ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007880.1|UniProtKB=W5MMG3 W5MMG3 PTHR12854:SF11 ATAXIN 2-RELATED ATAXIN-2 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694 cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008055.1|UniProtKB=W5MN23 W5MN23 PTHR23343:SF4 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 enzyme binding#GO:0019899;extracellular matrix structural constituent#GO:0005201;binding#GO:0005488;structural molecule activity#GO:0005198;protein binding#GO:0005515 sperm-egg recognition#GO:0035036;sexual reproduction#GO:0019953;cell recognition#GO:0008037;cell activation#GO:0001775;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988;negative regulation of biological process#GO:0048519;single fertilization#GO:0007338;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;fertilization#GO:0009566;reproductive process#GO:0022414 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013214.1|UniProtKB=W5N6L3 W5N6L3 PTHR21472:SF20 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000000421.1|UniProtKB=W5LWF0 W5LWF0 PTHR15907:SF107 DUF614 FAMILY PROTEIN-RELATED PLAC8 ONZIN-RELATED PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000011890.1|UniProtKB=W5N1W3 W5N1W3 PTHR16228:SF23 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000000550.1|UniProtKB=W5LWV0 W5LWV0 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED SI:DKEYP-69E1.8 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000014294.1|UniProtKB=W5NAD8 W5NAD8 PTHR18945:SF831 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-3 transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;acetylcholine receptor activity#GO:0015464;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261 trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;response to nitrogen compound#GO:1901698;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;transport#GO:0006810;establishment of localization#GO:0051234;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;neuromuscular synaptic transmission#GO:0007274;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA3#P06595;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 LEPOC|Ensembl=ENSLOCG00000004693.1|UniProtKB=W5MB65 W5MB65 PTHR10551:SF39 FASCIN FASCIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000012658.1|UniProtKB=W5N4M0 W5N4M0 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007351.1|UniProtKB=W5MKJ8 W5MKJ8 PTHR18875:SF3 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO CENTROSOMAL PROTEIN OF 63 KDA cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;developmental process#GO:0032502;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;centriole replication#GO:0007099;cell differentiation#GO:0030154;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000016593.1|UniProtKB=W5NIN4 W5NIN4 PTHR23186:SF6 RETINOIC ACID-INDUCED PROTEIN 2 SINE OCULIS-BINDING PROTEIN HOMOLOG A developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;animal organ development#GO:0048513 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000014952.1|UniProtKB=W5NCQ2 W5NCQ2 PTHR15746:SF22 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 1 secretion by cell#GO:0032940;exocytosis#GO:0006887;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;regulated exocytosis#GO:0045055;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000013494.1|UniProtKB=W5N7N3 W5N7N3 PTHR10909:SF397 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 1 organic acid binding#GO:0043177;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;fatty acid binding#GO:0005504;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008820.1|UniProtKB=W5MQS4 W5MQS4 PTHR23149:SF9 G PATCH DOMAIN CONTAINING PROTEIN G PATCH DOMAIN-CONTAINING PROTEIN 4 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013619.1|UniProtKB=W5N828 W5N828 PTHR13032:SF6 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542 organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967 LEPOC|Ensembl=ENSLOCG00000001623.1|UniProtKB=W5M0J5 W5M0J5 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001441.1|UniProtKB=W5LZV4 W5LZV4 PTHR24023:SF1112 COLLAGEN ALPHA COLLAGEN ALPHA-2(IX) CHAIN PRECURSOR-RELATED structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000003745.1|UniProtKB=W5M7X8 W5M7X8 PTHR10288:SF99 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 1 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008946.1|UniProtKB=W5MR91 W5MR91 PTHR10917:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 LEPOC|Ensembl=ENSLOCG00000006251.1|UniProtKB=W5MGP1 W5MGP1 PTHR19957:SF36 SYNTAXIN SYNTAXIN-2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 export from cell#GO:0140352;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;secretion by cell#GO:0032940;protein transport#GO:0015031;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;intracellular protein localization#GO:0008104;exocytosis#GO:0006887;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000005064.1|UniProtKB=W5MCI9 W5MCI9 PTHR11267:SF29 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX4 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;tube development#GO:0035295;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell fate specification#GO:0001708;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular process#GO:0009987;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;angiogenesis#GO:0001525;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 LEPOC|Ensembl=ENSLOCG00000008661.1|UniProtKB=W5MQ79 W5MQ79 PTHR10110:SF196 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000008765.1|UniProtKB=W5MQL1 W5MQL1 PTHR33198:SF26 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015804.1|UniProtKB=W5NFP6 W5NFP6 PTHR13480:SF0 E3 UBIQUITIN-PROTEIN LIGASE HAKAI-RELATED E3 UBIQUITIN-PROTEIN LIGASE HAKAI aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;cellular process#GO:0009987;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007443.1|UniProtKB=W5MKX0 W5MKX0 PTHR46241:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 4 ARMC4 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 2 LEPOC|Ensembl=ENSLOCG00000009056.1|UniProtKB=W5MRN2 W5MRN2 PTHR10807:SF51 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 11 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;dephosphorylation#GO:0016311;lipid modification#GO:0030258 membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000009838.1|UniProtKB=W5MUG7 W5MUG7 PTHR14995:SF2 AMNIONLESS PROTEIN AMNIONLESS intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;system process#GO:0003008;localization#GO:0051179;renal absorption#GO:0070293;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;renal system process#GO:0003014;cellular process#GO:0009987;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;apical part of cell#GO:0045177;signaling receptor complex#GO:0043235;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000001788.1|UniProtKB=W5M117 W5M117 PTHR12411:SF1048 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN K peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000018359.1|UniProtKB=W5NPA1 W5NPA1 PTHR12307:SF4 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3D protein phosphatase binding#GO:0019903;protein binding#GO:0005515;carbohydrate binding#GO:0030246;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247 biological regulation#GO:0065007;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of polysaccharide metabolic process#GO:0032881;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000016133.1|UniProtKB=W5NGW9 W5NGW9 PTHR15583:SF13 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 cell surface receptor signaling pathway#GO:0007166;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;response to cytokine#GO:0034097;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007357.1|UniProtKB=W5MKK3 W5MKK3 PTHR12271:SF133 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;mRNA processing#GO:0006397;RNA destabilization#GO:0050779;RNA processing#GO:0006396;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000013763.1|UniProtKB=W5N8L6 W5N8L6 PTHR18945:SF216 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-3 signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;synapse assembly#GO:0007416;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;cellular process#GO:0009987;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;chloride transport#GO:0006821;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502 leading edge membrane#GO:0031256;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection membrane#GO:0031253;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000014056.1|UniProtKB=W5N9L5 W5N9L5 PTHR11753:SF14 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-1A establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000010651.1|UniProtKB=W5MXE8 W5MXE8 PTHR18884:SF54 SEPTIN SEPTIN-8 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;cytokinesis#GO:0000910 cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000018298.1|UniProtKB=W5NP40 W5NP40 PTHR15284:SF6 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN NUCLEAR FACTOR, INTERLEUKIN 3 REGULATED, MEMBER 3 ISOFORM X1-RELATED regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;rhythmic process#GO:0048511;regulation of RNA metabolic process#GO:0051252;circadian rhythm#GO:0007623;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000010730.1|UniProtKB=W5MXN4 W5MXN4 PTHR47148:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013201.1|UniProtKB=W5N6J8 W5N6J8 PTHR24381:SF436 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 768 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000017031.1|UniProtKB=W5NK89 W5NK89 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 14A ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003985.1|UniProtKB=W5M8Q2 W5M8Q2 PTHR12533:SF10 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS 5 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;calcium-mediated signaling#GO:0019722;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;calcineurin-NFAT signaling cascade#GO:0033173;calcineurin-mediated signaling#GO:0097720;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;intracellular signaling cassette#GO:0141124;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851 LEPOC|Ensembl=ENSLOCG00000017647.1|UniProtKB=W5NM93 W5NM93 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018269.1|UniProtKB=W5NP11 W5NP11 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005988.1|UniProtKB=W5MFT8 W5MFT8 PTHR24180:SF11 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-2 catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 localization#GO:0051179;positive regulation of DNA metabolic process#GO:0051054;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;regulation of chromosome organization#GO:0033044;regulation of telomere maintenance#GO:0032204;intracellular protein localization#GO:0008104;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;positive regulation of signaling#GO:0023056;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular component organization#GO:0051128;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of Wnt signaling pathway#GO:0030177 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase inhibitor#PC00139;kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000006228.1|UniProtKB=W5MGL0 W5MGL0 PTHR31624:SF4 UPF0472 PROTEIN C16ORF72 HUWE1 ASSOCIATED PROTEIN MODIFYING STRESS RESPONSES LEPOC|Ensembl=ENSLOCG00000004227.1|UniProtKB=W5M9K0 W5M9K0 PTHR11822:SF44 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleotide metabolic process#GO:0006163;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;microbody#GO:0042579;cytosol#GO:0005829;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000009028.1|UniProtKB=W5MRJ3 W5MRJ3 PTHR12868:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009176.1|UniProtKB=W5MS32 W5MS32 PTHR13395:SF6 SISTER CHROMATID COHESION PROTEIN DCC1-RELATED SISTER CHROMATID COHESION PROTEIN DCC1 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276;mitotic sister chromatid cohesion#GO:0007064;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 replication origin binding protein#PC00199;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003779.1|UniProtKB=W5M800 W5M800 PTHR10177:SF187 CYCLINS CYCLIN-I kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000012633.1|UniProtKB=W5N4I9 W5N4I9 PTHR10156:SF0 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000000071.1|UniProtKB=W5LVC5 W5LVC5 PTHR11528:SF87 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-ALPHA ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367 response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;protein folding#GO:0006457;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;response to stress#GO:0006950;cellular response to heat#GO:0034605;response to heat#GO:0009408;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of protein stability#GO:0031647;gene expression#GO:0010467;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein stabilization#GO:0050821 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;cell body#GO:0044297;cytoplasm#GO:0005737;myelin sheath#GO:0043209;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;perinuclear region of cytoplasm#GO:0048471;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;nucleus#GO:0005634 chaperone#PC00072;Hsp90 family chaperone#PC00028 LEPOC|Ensembl=ENSLOCG00000014134.1|UniProtKB=W5N9V1 W5N9V1 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000003970.1|UniProtKB=W5M8N3 W5M8N3 PTHR22599:SF1 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB-LIKE PROTEIN PHOCEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000004637.1|UniProtKB=W5MB08 W5MB08 PTHR11254:SF293 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;negative regulation of BMP signaling pathway#GO:0030514;ubiquitin-dependent protein catabolic process#GO:0006511 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490;TGF-beta signaling pathway#P00052>Smurfs#P01279 LEPOC|Ensembl=ENSLOCG00000002453.1|UniProtKB=W5M3D3 W5M3D3 PTHR13025:SF7 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN FAMILY, MEMBER D2 calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000002778.1|UniProtKB=W5M4G1 W5M4G1 PTHR10760:SF4 TORSIN TORSIN-2A endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;organelle envelope#GO:0031967 chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 LEPOC|Ensembl=ENSLOCG00000002503.1|UniProtKB=W5M3I1 W5M3I1 PTHR23257:SF757 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016391.1|UniProtKB=W5NHY2 W5NHY2 PTHR45712:SF14 AGAP008170-PA DECORIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017555.1|UniProtKB=W5NM01 W5NM01 PTHR46473:SF29 GH08155P LD45603P LEPOC|Ensembl=ENSLOCG00000015481.1|UniProtKB=W5NEJ5 W5NEJ5 PTHR10126:SF42 TATA-BOX BINDING PROTEIN TATA-BOX-BINDING PROTEIN macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;Huntington disease#P00029>TBP#P00779 LEPOC|Ensembl=ENSLOCG00000010183.1|UniProtKB=W5MVR9 W5MVR9 CMPK1 PTHR23359:SF206 NUCLEOTIDE KINASE UMP-CMP KINASE catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;nucleoside diphosphate metabolic process#GO:0009132;ribonucleotide metabolic process#GO:0009259;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896;Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153;De novo pyrimidine ribonucleotides biosythesis#P02740>Uridylate kinase#P02924 LEPOC|Ensembl=ENSLOCG00000005155.1|UniProtKB=W5MCV4 W5MCV4 PTHR12308:SF13 ANOCTAMIN ANOCTAMIN-1 monoatomic anion channel activity#GO:0005253;intramembrane lipid carrier activity#GO:0140303;channel activity#GO:0015267;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;ligand-gated monoatomic ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;molecular carrier activity#GO:0140104;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509 chloride transport#GO:0006821;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;monoatomic anion transmembrane transport#GO:0098656;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;lipid localization#GO:0010876;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic anion transport#GO:0006820;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016003.1|UniProtKB=W5NGE9 W5NGE9 PTHR24241:SF146 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PROKINETICIN RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004798.1|UniProtKB=W5MBK7 W5MBK7 PTHR24161:SF16 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE ZDHHC13 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017971.1|UniProtKB=W5NN63 W5NN63 PTHR23401:SF2 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 1 cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;protein kinase activator activity#GO:0030295;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;brain development#GO:0007420;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;anatomical structure development#GO:0048856;system development#GO:0048731;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;head development#GO:0060322;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;growth cone#GO:0030426;axon#GO:0030424;cellular anatomical structure#GO:0110165;distal axon#GO:0150034;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuron projection#GO:0043005 kinase activator#PC00138;kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000016859.1|UniProtKB=W5NJN4 W5NJN4 PTHR14625:SF3 MICROCEPHALIN MICROCEPHALIN cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000006964.1|UniProtKB=W5MJ77 W5MJ77 PTHR23303:SF14 CARBOXYPEPTIDASE REGULATORY REGION-CONTAINING BOS COMPLEX SUBUNIT NOMO1-RELATED endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000002813.1|UniProtKB=W5M4K1 W5M4K1 PTHR23255:SF51 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-2 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine receptor binding#GO:0005126;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;kinase activity#GO:0016301;activin binding#GO:0048185;transforming growth factor beta receptor activity#GO:0005024;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;signaling receptor binding#GO:0005102;molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transforming growth factor beta binding#GO:0050431;cytokine binding#GO:0019955;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;activin receptor signaling pathway#GO:0032924;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165 signaling receptor complex#GO:0043235;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 serine/threonine protein kinase receptor#PC00205 LEPOC|Ensembl=ENSLOCG00000012565.1|UniProtKB=W5N4B3 W5N4B3 PTHR46792:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 80 COILED-COIL DOMAIN-CONTAINING 80-LIKE 2 extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;positive regulation of cell-substrate adhesion#GO:0010811;cellular process#GO:0009987;positive regulation of cell adhesion#GO:0045785;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular component organization#GO:0016043;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 LEPOC|Ensembl=ENSLOCG00000016993.1|UniProtKB=W5NK49 W5NK49 PTHR11570:SF0 S-ADENOSYLMETHIONINE DECARBOXYLASE S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME metabolite interconversion enzyme#PC00262;lyase#PC00144;decarboxylase#PC00089 LEPOC|Ensembl=ENSLOCG00000016688.1|UniProtKB=W5NJ10 W5NJ10 PTHR11834:SF2 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;hippo signaling#GO:0035329;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000015553.1|UniProtKB=W5NET8 W5NET8 PTHR24240:SF16 OPSIN SHORT-WAVE-SENSITIVE OPSIN 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;biological regulation#GO:0065007;detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;signaling#GO:0023052;cellular response to radiation#GO:0071478;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004666.1|UniProtKB=W5MB32 W5MB32 PTHR22770:SF47 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF216 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;regulation of vesicle-mediated transport#GO:0060627;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of receptor-mediated endocytosis#GO:0048259;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of endocytosis#GO:0030100;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of transport#GO:0051049;regulation of localization#GO:0032879;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007 postsynapse#GO:0098794;presynapse#GO:0098793;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;cell junction#GO:0030054;intracellular protein-containing complex#GO:0140535 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001756.1|UniProtKB=W5M0Z7 W5M0Z7 PTHR11134:SF9 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-2 COMPLEX SUBUNIT BETA clathrin binding#GO:0030276;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;protein binding#GO:0005515 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810 coated membrane#GO:0048475;endocytic vesicle#GO:0030139;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated endocytic vesicle#GO:0045334;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin vesicle coat#GO:0030125;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;organelle membrane#GO:0031090;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;trans-Golgi network transport vesicle membrane#GO:0012510;clathrin-coated vesicle#GO:0030136;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;plasma membrane#GO:0005886;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012270.1|UniProtKB=W5N389 W5N389 PTHR23254:SF15 EIF4G DOMAIN PROTEIN POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1 translation regulator activity#GO:0045182 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017940.1|UniProtKB=W5NN34 W5NN34 PTHR23189:SF43 RNA RECOGNITION MOTIF-CONTAINING RNA-BINDING PROTEIN 15 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006098.1|UniProtKB=W5MG54 W5MG54 PTHR14759:SF37 STOP PROTEIN MAP6 DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 establishment of localization#GO:0051234;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;cis-Golgi network#GO:0005801;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000000896.1|UniProtKB=W5LY05 W5LY05 PTHR22826:SF201 RHO GUANINE EXCHANGE FACTOR-RELATED GUANINE NUCLEOTIDE EXCHANGE FACTOR MCF2L2-RELATED guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014186.1|UniProtKB=W5NA15 W5NA15 PTHR11599:SF11 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;proteasome complex#GO:0000502 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000004704.1|UniProtKB=W5MB77 W5MB77 PTHR24247:SF31 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2B neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;synaptic signaling#GO:0099536;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;trans-synaptic signaling#GO:0099537;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268 dendrite#GO:0030425;dendritic tree#GO:0097447;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414 LEPOC|Ensembl=ENSLOCG00000012284.1|UniProtKB=W5N3B1 W5N3B1 PTHR13246:SF1 ENDO BETA N-ACETYLGLUCOSAMINIDASE CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 hydrolase#PC00121;deaminase#PC00088 LEPOC|Ensembl=ENSLOCG00000005418.1|UniProtKB=W5MDS6 W5MDS6 PTHR34920:SF1 B-CELL LYMPHOMA/LEUKEMIA 10 B-CELL LYMPHOMA_LEUKEMIA 10 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;molecular function activator activity#GO:0140677;kinase binding#GO:0019900;binding#GO:0005488;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;transcription coactivator activity#GO:0003713;kinase regulator activity#GO:0019207;enzyme activator activity#GO:0008047;kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712 positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;immune system process#GO:0002376;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000006782.1|UniProtKB=W5MII1 W5MII1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000014540.1|UniProtKB=W5NB91 W5NB91 PTHR24115:SF445 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF7 ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000012879.1|UniProtKB=W5N5E4 W5N5E4 PTHR23285:SF8 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX3C RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005233.1|UniProtKB=W5MD68 W5MD68 PTHR11361:SF158 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH3 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular response to stress#GO:0033554;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;immune system development#GO:0002520;mismatch repair#GO:0006298;production of molecular mediator of immune response#GO:0002440;response to stimulus#GO:0050896;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;multicellular organism development#GO:0007275;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;response to stress#GO:0006950;gene expression#GO:0010467;mitotic recombination#GO:0006312;system development#GO:0048731;anatomical structure development#GO:0048856;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA damage response#GO:0006974;developmental process#GO:0032502;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;somatic cell DNA recombination#GO:0016444;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;multicellular organismal process#GO:0032501 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003134.1|UniProtKB=W5M5P3 W5M5P3 PTHR46054:SF2 MATERNAL EFFECT PROTEIN STAUFEN DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;double-stranded RNA binding#GO:0003725 developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell differentiation#GO:0030154;microtubule-based movement#GO:0007018;RNA localization#GO:0006403;gamete generation#GO:0007276;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;protein localization to cell junction#GO:1902414;microtubule-based transport#GO:0099111;sexual reproduction#GO:0019953;localization#GO:0051179;anatomical structure development#GO:0048856;cellular localization#GO:0051641;multicellular organismal reproductive process#GO:0048609;macromolecule localization#GO:0033036;axo-dendritic transport#GO:0008088;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;intracellular transport#GO:0046907;developmental process#GO:0032502;transport#GO:0006810;protein localization to synapse#GO:0035418;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494 LEPOC|Ensembl=ENSLOCG00000016723.1|UniProtKB=W5NJ56 W5NJ56 PTHR24223:SF330 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 10 transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;xenobiotic transmembrane transporter activity#GO:0042910 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000003078.1|UniProtKB=W5M5G3 W5M5G3 PTHR13869:SF38 MYELIN P0 RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000009831.1|UniProtKB=W5MUH0 W5MUH0 PTHR10783:SF141 XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED SOLUTE CARRIER FAMILY 53 MEMBER 1 phosphate transmembrane transporter activity#GO:0005315;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;efflux transmembrane transporter activity#GO:0015562;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;homeostatic process#GO:0042592;export from cell#GO:0140352;phosphate ion transport#GO:0006817;transport#GO:0006810;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698;cellular homeostasis#GO:0019725 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000015602.1|UniProtKB=W5NF02 W5NF02 PTHR10615:SF26 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT6A histone acetyltransferase activity#GO:0004402;chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transcription regulator activity#GO:0140110;binding#GO:0005488;acetyltransferase activity#GO:0016407;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009751.1|UniProtKB=W5MU51 W5MU51 PTHR24248:SF199 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014173.1|UniProtKB=W5N9Z7 W5N9Z7 PTHR11346:SF86 GALECTIN GALECTIN binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000018357.1|UniProtKB=W5NP99 W5NP99 PTHR22750:SF4 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 3 molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;hormone binding#GO:0042562 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004372.1|UniProtKB=W5MA19 W5MA19 PTHR10802:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 HOMOLOG transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011403.1|UniProtKB=W5N061 W5N061 PTHR12428:SF70 OXA1 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 localization#GO:0051179;cellular localization#GO:0051641;respiratory chain complex IV assembly#GO:0008535;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016786.1|UniProtKB=W5NJE0 W5NJE0 PTHR11216:SF67 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization within membrane#GO:0051668;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;cell projection organization#GO:0030030;endocytic recycling#GO:0032456;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607 bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;recycling endosome#GO:0055037;cytoplasm#GO:0005737;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endocytic vesicle#GO:0030139;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014775.1|UniProtKB=W5NC33 W5NC33 PTHR21737:SF3 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 POLYGLUTAMINE-BINDING PROTEIN 1 protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006623.1|UniProtKB=W5MHZ3 W5MHZ3 PTHR22950:SF226 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 38 MEMBER 8 L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000008076.1|UniProtKB=W5MN49 W5MN49 PTHR26451:SF889 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005626.1|UniProtKB=W5MEI4 W5MEI4 PTHR10623:SF20 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;microtubule end#GO:1990752;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000003536.1|UniProtKB=W5M724 W5M724 PTHR13314:SF2 CALCIUM CHANNEL FLOWER HOMOLOG CALCIUM CHANNEL FLOWER HOMOLOG transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 transport#GO:0006810;synaptic vesicle cycle#GO:0099504;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;calcium ion transport#GO:0006816;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;cellular localization#GO:0051641;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;synaptic vesicle endocytosis#GO:0048488;endocytosis#GO:0006897;metal ion transport#GO:0030001 exocytic vesicle#GO:0070382;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;presynapse#GO:0098793;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008541.1|UniProtKB=W5MPU4 W5MPU4 PTHR10336:SF79 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA lipase activity#GO:0016298;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 intracellular signal transduction#GO:0035556;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of cell motility#GO:2000145;cell communication#GO:0007154;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;positive regulation of locomotion#GO:0040017;establishment of localization#GO:0051234;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;transport#GO:0006810;regulation of cell migration#GO:0030334;regulation of locomotion#GO:0040012;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;organophosphate metabolic process#GO:0019637;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;calcium ion transmembrane transport#GO:0070588;positive regulation of cell motility#GO:2000147;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;metabolic process#GO:0008152;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;ruffle#GO:0001726;cell projection membrane#GO:0031253;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 hydrolase#PC00121;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143 LEPOC|Ensembl=ENSLOCG00000005165.1|UniProtKB=W5MCW1 W5MCW1 PTHR13059:SF10 HMG-BOX TRANSCRIPTION FACTOR BBX HMG BOX TRANSCRIPTION FACTOR BBX transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000010165.1|UniProtKB=W5MVP2 W5MVP2 PTHR24115:SF191 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF9 ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016059.1|UniProtKB=W5NGN0 W5NGN0 PTHR43511:SF4 FAMILY NOT NAMED UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE LEPOC|Ensembl=ENSLOCG00000013085.1|UniProtKB=W5N657 W5N657 PTHR13502:SF10 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CDC42 SMALL EFFECTOR 2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000009419.1|UniProtKB=W5MSY4 W5MSY4 RNF11 PTHR46359:SF1 GEO07743P1 RING FINGER PROTEIN 11 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000001584.1|UniProtKB=W5M0J9 W5M0J9 PTHR45628:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT N-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1B voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245 monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;transport#GO:0006810;import across plasma membrane#GO:0098739;anterograde trans-synaptic signaling#GO:0098916;inorganic ion import across plasma membrane#GO:0099587;signaling#GO:0023052;metal ion transport#GO:0030001;chemical synaptic transmission#GO:0007268;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537 cation channel complex#GO:0034703;transporter complex#GO:1990351;membrane#GO:0016020;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;transmembrane transporter complex#GO:1902495;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;cell body#GO:0044297;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025 voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;GABA-B receptor II signaling#P05731>Ca channel#P05753;Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 LEPOC|Ensembl=ENSLOCG00000010089.1|UniProtKB=W5MVD2 W5MVD2 PTHR10901:SF5 TROPOMODULIN LEIOMODIN-1 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;multicellular organismal process#GO:0032501;actin filament organization#GO:0007015;system process#GO:0003008;cellular developmental process#GO:0048869;muscle contraction#GO:0006936;developmental process#GO:0032502 contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000007326.1|UniProtKB=W5MKG1 W5MKG1 PTHR20939:SF1 SORTING NEXIN 20, 21 SORTING NEXIN-20 lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;binding#GO:0005488 vesicle membrane#GO:0012506;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;early endosome membrane#GO:0031901;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008883.1|UniProtKB=W5MR07 W5MR07 PTHR11764:SF94 TERPENE CYCLASE/MUTASE FAMILY MEMBER LANOSTEROL SYNTHASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652 intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cyclase#PC00079;lyase#PC00144 Cholesterol biosynthesis#P00014>Anosterol synthase#P00497 LEPOC|Ensembl=ENSLOCG00000014596.1|UniProtKB=W5NBF3 W5NBF3 PTHR11409:SF42 ADENOSINE DEAMINASE N6-METHYL-AMP DEAMINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;adenosine deaminase activity#GO:0004000;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;nucleobase metabolic process#GO:0009112;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;purine nucleobase metabolic process#GO:0006144;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;nucleoside catabolic process#GO:0009164;purine nucleoside metabolic process#GO:0042278;purine-containing compound biosynthetic process#GO:0072522 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 deaminase#PC00088 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 LEPOC|Ensembl=ENSLOCG00000004393.1|UniProtKB=W5MA43 W5MA43 PTHR13598:SF4 AT07567P-RELATED NUCLEAR ENVELOPE INTEGRAL MEMBRANE PROTEIN 1 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001578.1|UniProtKB=W5M099 W5M099 PTHR15427:SF23 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMI DOMAIN-CONTAINING PROTEIN 1 positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004122.1|UniProtKB=W5M966 W5M966 PTHR43671:SF111 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK11 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;negative regulation of cell cycle#GO:0045786;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;DNA integrity checkpoint signaling#GO:0031570;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000000651.1|UniProtKB=W5LX63 W5LX63 PTHR11716:SF4 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP 10 SECRETORY PHOSPHOLIPASE A2 cation binding#GO:0043169;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;ion binding#GO:0043167;lipase activity#GO:0016298;small molecule binding#GO:0036094;hydrolase activity, acting on ester bonds#GO:0016788;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;lipid binding#GO:0008289;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;glycerolipid metabolic process#GO:0046486;phosphatidylcholine metabolic process#GO:0046470;phosphatidylglycerol metabolic process#GO:0046471;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000012996.1|UniProtKB=W5N5U6 W5N5U6 PTHR12027:SF82 WNT RELATED PROTO-ONCOGENE WNT-3 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102 multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 LEPOC|Ensembl=ENSLOCG00000007282.1|UniProtKB=W5MKA6 W5MKA6 PTHR18945:SF74 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;acetylcholine receptor activity#GO:0015464;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;modulation of chemical synaptic transmission#GO:0050804;striated muscle contraction#GO:0006941;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;neuromuscular process#GO:0050905;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;multicellular organismal process#GO:0032501;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;establishment of localization#GO:0051234;system process#GO:0003008;transport#GO:0006810;muscle contraction#GO:0006936;response to stimulus#GO:0050896;signaling#GO:0023052;skeletal muscle contraction#GO:0003009;muscle system process#GO:0003012;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cellular response to chemical stimulus#GO:0070887;nervous system process#GO:0050877;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;neuromuscular synaptic transmission#GO:0007274 transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 LEPOC|Ensembl=ENSLOCG00000013812.1|UniProtKB=W5N8S7 W5N8S7 PTHR13532:SF3 FAMILY NOT NAMED INTEGRATOR COMPLEX SUBUNIT 14 LEPOC|Ensembl=ENSLOCG00000016941.1|UniProtKB=W5NJZ4 W5NJZ4 PTHR13902:SF46 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK1 molecular function inhibitor activity#GO:0140678;protein kinase activity#GO:0004672;channel regulator activity#GO:0016247;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;protein serine/threonine kinase activity#GO:0004674;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062;chemical homeostasis#GO:0048878;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of metal ion transport#GO:0010959;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007982.1|UniProtKB=W5MMU4 W5MMU4 PTHR20765:SF1 SOLUTE CARRIER FAMILY 43 MEMBER 3-RELATED EQUILIBRATIVE NUCLEOBASE TRANSPORTER 1 secondary carrier transporter#PC00258;amino acid transporter#PC00046 LEPOC|Ensembl=ENSLOCG00000002258.1|UniProtKB=W5M2M9 W5M2M9 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002765.1|UniProtKB=W5M4E9 W5M4E9 PTHR11486:SF18 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 14 fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;ion channel regulator activity#GO:0099106;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function activator activity#GO:0140677;channel regulator activity#GO:0016247;signaling receptor binding#GO:0005102;binding#GO:0005488;transporter regulator activity#GO:0141108 regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of cell migration#GO:0030334;response to fibroblast growth factor#GO:0071774;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;nervous system development#GO:0007399;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000018241.1|UniProtKB=W5NNY3 W5NNY3 PTHR24235:SF21 NEUROPEPTIDE Y RECEPTOR PROLACTIN RELEASING HORMONE RECEPTOR neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006224.1|UniProtKB=W5MGM4 W5MGM4 PTHR13318:SF169 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 9 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000006705.1|UniProtKB=W5MI91 W5MI91 PTHR14024:SF11 PERILIPIN PERILIPIN-3 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;lipid storage#GO:0019915;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of localization#GO:0032879 cytosol#GO:0005829;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012853.1|UniProtKB=W5N5B6 W5N5B6 PTHR22619:SF1 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 8 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 LEPOC|Ensembl=ENSLOCG00000009545.1|UniProtKB=W5MTG6 W5MTG6 PTHR45620:SF12 PDF RECEPTOR-LIKE PROTEIN-RELATED PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE TYPE I RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PAC1R#G06898;Gonadotropin-releasing hormone receptor pathway#P06664>PAC1-R#P06712;Gonadotropin-releasing hormone receptor pathway#P06664>PAC1R#G06685 LEPOC|Ensembl=ENSLOCG00000016921.1|UniProtKB=W5NJV9 W5NJV9 PTHR15507:SF14 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN 292 DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013472.1|UniProtKB=W5N7K1 W5N7K1 PTHR45891:SF2 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000003496.1|UniProtKB=W5M6Y8 W5M6Y8 PTHR10706:SF161 F-BOX FAMILY PROTEIN F-BOX ONLY PROTEIN 31 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012406.1|UniProtKB=W5N3R4 W5N3R4 PTHR47977:SF58 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-15 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000001804.1|UniProtKB=W5M135 W5M135 PTHR14463:SF10 LIPASE MATURATION FACTOR LIPASE MATURATION FACTOR 1 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000001716.1|UniProtKB=W5M0X7 W5M0X7 PTHR46682:SF1 ADHESION G-PROTEIN COUPLED RECEPTOR V1 ADHESION G PROTEIN-COUPLED RECEPTOR V1 enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular transducer activity#GO:0060089;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;cyclase inhibitor activity#GO:0010852;adenylate cyclase inhibitor activity#GO:0010855;transmembrane signaling receptor activity#GO:0004888;adenylate cyclase regulator activity#GO:0010854;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;cyclase regulator activity#GO:0010851 response to calcium ion#GO:0051592;system process#GO:0003008;cellular response to chemical stimulus#GO:0070887;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;response to metal ion#GO:0010038;multicellular organismal process#GO:0032501;visual perception#GO:0007601;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of sound#GO:0007605;sensory perception of light stimulus#GO:0050953;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;stereocilium#GO:0032420;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005948.1|UniProtKB=W5MFM6 W5MFM6 PTHR46574:SF1 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, cholinergic#GO:0007271;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;positive regulation of synaptic transmission#GO:0050806;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;positive regulation of signaling#GO:0023056 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;synapse#GO:0045202;neuromuscular junction#GO:0031594;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000011556.1|UniProtKB=W5N0N8 W5N0N8 PTHR12486:SF4 APRATAXIN-RELATED APRATAXIN hydrolase activity, acting on acid anhydrides#GO:0016817;damaged DNA binding#GO:0003684;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;single-stranded DNA binding#GO:0003697;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;RNA binding#GO:0003723;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000013989.1|UniProtKB=W5N9D1 W5N9D1 PTHR12002:SF74 CLAUDIN CLAUDIN-15 transporter activity#GO:0005215;paracellular tight junction channel activity#GO:0160187 cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184 bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000013376.1|UniProtKB=W5N778 W5N778 PTHR13620:SF133 3-5 EXONUCLEASE EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2 catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;hydrolase activity#GO:0016787;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 DNA damage response#GO:0006974;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;recombinational repair#GO:0000725;RNA metabolic process#GO:0016070;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000005470.1|UniProtKB=W5MDY6 W5MDY6 PTHR46484:SF7 SI:CH211-171H4.5-RELATED MYELIN-ASSOCIATED GLYCOPROTEIN ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000012163.1|UniProtKB=W5N2W8 W5N2W8 PTHR45703:SF48 DYNEIN HEAVY CHAIN DYNEIN AXONEMAL HEAVY CHAIN 17 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000004718.1|UniProtKB=W5MB97 W5MB97 PTHR24240:SF151 OPSIN NOVOPSIN-5-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;signal transduction#GO:0007165;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;detection of stimulus#GO:0051606;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to radiation#GO:0071478;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013611.1|UniProtKB=W5N841 W5N841 PTHR11771:SF161 LIPOXYGENASE ARACHIDONATE 15-LIPOXYGENASE TYPE B oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;arachidonate metabolic process#GO:0019369;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid oxidation#GO:0034440;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003279.1|UniProtKB=W5M661 W5M661 PTHR12585:SF71 SCC1 / RAD21 FAMILY MEMBER DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21 HOMOLOG A-RELATED chromatin binding#GO:0003682;binding#GO:0005488 chromosome organization#GO:0051276;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;organelle organization#GO:0006996;response to stress#GO:0006950;sister chromatid cohesion#GO:0007062;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membraneless organelle#GO:0043232;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008008.1|UniProtKB=W5MMW9 W5MMW9 PTHR12548:SF5 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000012059.1|UniProtKB=W5N2H3 W5N2H3 PTHR10740:SF11 TRANSFORMING GROWTH FACTOR ALPHA PROEPIREGULIN molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;positive regulation of cell population proliferation#GO:0008284;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cellular component organization#GO:0051130;regulation of nuclear division#GO:0051783;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;epidermal growth factor receptor signaling pathway#GO:0007173;ERBB signaling pathway#GO:0038127;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;regulation of mitotic nuclear division#GO:0007088;cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 LEPOC|Ensembl=ENSLOCG00000014312.1|UniProtKB=W5NAG3 W5NAG3 PTHR13622:SF16 THIAMIN PYROPHOSPHOKINASE SI:DKEY-6N6.2 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787 kinase#PC00137;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000002931.1|UniProtKB=W5M4Z5 W5M4Z5 PTHR46914:SF1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 enzyme regulator activity#GO:0030234;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 response to other organism#GO:0051707;biological regulation#GO:0065007;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;detection of stimulus#GO:0051606;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of apoptotic process#GO:0042981;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;inflammatory response#GO:0006954;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;canonical inflammasome complex#GO:0061702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000013550.1|UniProtKB=W5N7U7 W5N7U7 PTHR43205:SF5 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 small molecule metabolic process#GO:0044281;icosanoid metabolic process#GO:0006690;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;prostaglandin metabolic process#GO:0006693;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629 reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000012159.1|UniProtKB=W5N2V0 W5N2V0 PTHR11129:SF1 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000012431.1|UniProtKB=W5N3U8 W5N3U8 PTHR11675:SF41 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 10 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009878.1|UniProtKB=W5MUL7 W5MUL7 PTHR10024:SF223 SYNAPTOTAGMIN SYNAPTOTAGMIN-2 phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;protein binding#GO:0005515 synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;regulation of exocytosis#GO:0017157;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of vesicle fusion#GO:0031340;exocytosis#GO:0006887;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular component organization#GO:0051128;regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;export from cell#GO:0140352 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular vesicle#GO:0097708;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;axon#GO:0030424;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000002549.1|UniProtKB=W5M3P2 W5M3P2 PTHR10332:SF8 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337 transport#GO:0006810;pyrimidine nucleobase transport#GO:0015855;nucleobase transport#GO:0015851;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001562.1|UniProtKB=W5M080 W5M080 PTHR21621:SF10 RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN BETA-CITRYLGLUTAMATE SYNTHASE B-RELATED ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006443.1|UniProtKB=W5MHE7 W5MHE7 PTHR12124:SF47 POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED EXOSOME COMPLEX COMPONENT 10 LEPOC|Ensembl=ENSLOCG00000003839.1|UniProtKB=W5M876 W5M876 PTHR35450:SF2 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN C1Q DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017464.1|UniProtKB=W5NLR0 W5NLR0 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006334.1|UniProtKB=W5MGZ1 W5MGZ1 PTHR44662:SF1 WD REPEAT-CONTAINING PROTEIN 81 WD REPEAT-CONTAINING PROTEIN 81 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 metabolic process#GO:0008152;cellular process#GO:0009987;autophagy#GO:0006914;catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;macroautophagy#GO:0016236 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005925.1|UniProtKB=W5MFK1 W5MFK1 PTHR11089:SF9 GTP-BINDING PROTEIN-RELATED NUCLEOLAR GTP-BINDING PROTEIN 2 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000007153.1|UniProtKB=W5MJU9 W5MJU9 PTHR45752:SF196 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 4 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002379.1|UniProtKB=W5M333 W5M333 PTHR22913:SF6 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 3 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;cellular component organization#GO:0016043;aminoglycan biosynthetic process#GO:0006023;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;aminoglycan metabolic process#GO:0006022;extracellular structure organization#GO:0043062;polysaccharide biosynthetic process#GO:0000271;cellular component assembly#GO:0022607;extracellular matrix assembly#GO:0085029;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016968.1|UniProtKB=W5NK16 W5NK16 PTHR15532:SF3 FAMILY NOT NAMED DERMATAN-SULFATE EPIMERASE isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 LEPOC|Ensembl=ENSLOCG00000003539.1|UniProtKB=W5M733 W5M733 PTHR11255:SF36 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE GAMMA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;biological regulation#GO:0065007;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;neutral lipid metabolic process#GO:0006638;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002446.1|UniProtKB=W5M3B5 W5M3B5 PTHR42687:SF5 L-THREONINE 3-DEHYDROGENASE L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013928.1|UniProtKB=W5N966 W5N966 PTHR12845:SF7 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 15 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of actin filament-based process#GO:0032970;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000007661.1|UniProtKB=W5MLP5 W5MLP5 PTHR45888:SF2 HL01030P-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE 2D transcription coactivator activity#GO:0003713;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;transcription regulator activity#GO:0140110;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;histone H3 methyltransferase activity#GO:0140938;histone H3K4 methyltransferase activity#GO:0042800;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000016915.1|UniProtKB=W5NJV4 W5NJV4 PTHR11848:SF139 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 5 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;cellular process#GO:0009987;signal transduction#GO:0007165;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000014412.1|UniProtKB=W5NAT2 W5NAT2 PTHR15907:SF34 DUF614 FAMILY PROTEIN-RELATED PLAC8 ONZIN-RELATED PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000001497.1|UniProtKB=W5M001 W5M001 PTHR23266:SF403 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;binding#GO:0005488 immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007587.1|UniProtKB=W5MLE8 W5MLE8 PTHR20913:SF11 TBC1 DOMAIN FAMILY MEMBER 20/GTPASE TBC1 DOMAIN FAMILY MEMBER 20 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;organelle organization#GO:0006996;cellular component organization#GO:0016043;establishment of localization in cell#GO:0051649;Golgi organization#GO:0007030;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013471.1|UniProtKB=W5N7K9 W5N7K9 PTHR13129:SF6 VPRBP PROTEIN-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transcription factor binding#GO:0008134;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;histone kinase activity#GO:0035173;nuclear receptor binding#GO:0016922;transferase activity#GO:0016740;kinase activity#GO:0016301;nuclear estrogen receptor binding#GO:0030331 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000001223.1|UniProtKB=W5LZ28 W5LZ28 PTHR13425:SF3 HEADCASE PROTEIN HEADCASE PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000009879.1|UniProtKB=W5MUL6 W5MUL6 PTHR12281:SF16 RP42 RELATED DCN1-LIKE PROTEIN 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;binding#GO:0005488;protein binding#GO:0005515 positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of protein modification process#GO:0031399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of protein modification by small protein conjugation or removal#GO:1903320;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016645.1|UniProtKB=W5NIV1 W5NIV1 PTHR28581:SF1 CONSORTIN CONSORTIN protein binding#GO:0005515;binding#GO:0005488 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;positive regulation of biological process#GO:0048518;regulation of protein localization to membrane#GO:1905475;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522 Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 LEPOC|Ensembl=ENSLOCG00000004494.1|UniProtKB=W5MAG0 W5MAG0 PTHR46942:SF1 SIALIC ACID-BINDING IG-LIKE LECTIN 15 SIALIC ACID-BINDING IG-LIKE LECTIN 15 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of actin cytoskeleton organization#GO:0032956;regulation of cell development#GO:0060284;regulation of bone remodeling#GO:0046850;regulation of cell differentiation#GO:0045595;regulation of actin filament-based process#GO:0032970;regulation of developmental process#GO:0050793;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of multicellular organismal development#GO:2000026;regulation of tissue remodeling#GO:0034103;regulation of hemopoiesis#GO:1903706;regulation of bone resorption#GO:0045124 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000006140.1|UniProtKB=W5MGA9 W5MGA9 PTHR35979:SF1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009445.1|UniProtKB=W5MT19 W5MT19 PTHR10558:SF2 SOMATOSTATIN SOMATOSTATIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010167.1|UniProtKB=W5MVN5 W5MVN5 PTHR15131:SF3 SMALL NUCLEAR RNA ACTIVATING COMPLEX, POLYPEPTIDE 1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 1 DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676 transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA transcription#GO:0009301;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;snRNA transcription by RNA polymerase III#GO:0042796;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 LEPOC|Ensembl=ENSLOCG00000003227.1|UniProtKB=W5M601 W5M601 PTHR11477:SF14 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A N-TERMINAL AND CENTRAL DOMAIN-CONTAINING PROTEIN 2 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005274.1|UniProtKB=W5MD97 W5MD97 PTHR22951:SF16 CLATHRIN ASSEMBLY PROTEIN PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN phosphatidylinositol phosphate binding#GO:1901981;SNARE binding#GO:0000149;clathrin binding#GO:0030276;phospholipid binding#GO:0005543;lipid binding#GO:0008289;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 cellular component organization#GO:0016043;organelle organization#GO:0006996;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898 plasma membrane region#GO:0098590;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734;secretory vesicle#GO:0099503;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;clathrin-coated vesicle#GO:0030136;synaptic membrane#GO:0097060;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000002485.1|UniProtKB=W5M3H1 W5M3H1 PTHR10177:SF401 CYCLINS CYCLIN-O protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772 intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000018108.1|UniProtKB=W5NNK0 W5NNK0 PTHR28613:SF9 SI:CH211-232M10.4-RELATED TRANSMEMBRANE PROTEIN 238 LEPOC|Ensembl=ENSLOCG00000007841.1|UniProtKB=W5MMC0 W5MMC0 PTHR11827:SF9 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 3 monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;potassium ion transmembrane transporter activity#GO:0015079;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;monoatomic anion transport#GO:0006820;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009395.1|UniProtKB=W5MSV1 W5MSV1 PTHR22602:SF0 IRON-SULFUR CLUSTER ASSEMBLY FACTOR CAF17/IBA57, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY FACTOR IBA57, MITOCHONDRIAL membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000012260.1|UniProtKB=W5N376 W5N376 PTHR10151:SF63 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 7 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;lipase activity#GO:0016298;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;sphingomyelin metabolic process#GO:0006684 membrane#GO:0016020;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013229.1|UniProtKB=W5N6N7 W5N6N7 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED binding#GO:0005488;signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010436.1|UniProtKB=W5MWN6 W5MWN6 PTHR31626:SF1 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171A1 stress fiber assembly#GO:0043149;supramolecular fiber organization#GO:0097435;regulation of biological quality#GO:0065008;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;regulation of developmental process#GO:0050793;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;regulation of biological process#GO:0050789;actin filament bundle organization#GO:0061572;regulation of cell shape#GO:0008360;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;actin filament organization#GO:0007015;cellular component assembly#GO:0022607;contractile actin filament bundle assembly#GO:0030038;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013540.1|UniProtKB=W5N7U2 W5N7U2 PTHR14795:SF0 HELICASE RELATED TRANSMEMBRANE PROTEIN 62 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010695.1|UniProtKB=W5MXJ5 W5MXJ5 PTHR23510:SF83 INNER MEMBRANE TRANSPORT PROTEIN YAJR MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 8 channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular component disassembly#GO:0022411;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;autophagosome maturation#GO:0097352;lytic vacuole organization#GO:0080171;macroautophagy#GO:0016236;organelle organization#GO:0006996;autophagy#GO:0006914;lysosome organization#GO:0007040;cellular process#GO:0009987 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000014781.1|UniProtKB=W5NC46 W5NC46 PTHR24300:SF437 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C44 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466 membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002455.1|UniProtKB=W5M3C7 W5M3C7 PTHR10072:SF41 IRON-SULFUR CLUSTER ASSEMBLY PROTEIN IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;iron-sulfur cluster assembly#GO:0016226;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004987.1|UniProtKB=W5MC92 W5MC92 PTHR15044:SF0 NEUROPEPTIDE FF PRO-FMRFAMIDE-RELATED NEUROPEPTIDE FF neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;immune response#GO:0006955;regulation of blood pressure#GO:0008217;defense response#GO:0006952;system process#GO:0003008;chemical synaptic transmission, postsynaptic#GO:0099565;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;regulation of postsynaptic membrane potential#GO:0060078;neuropeptide signaling pathway#GO:0007218;chemical synaptic transmission#GO:0007268;acute inflammatory response#GO:0002526;cell communication#GO:0007154;inflammatory response#GO:0006954;trans-synaptic signaling#GO:0099537;circulatory system process#GO:0003013;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;synaptic signaling#GO:0099536;regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;positive regulation of blood pressure#GO:0045777;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;nervous system process#GO:0050877;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186 cell junction#GO:0030054;axon terminus#GO:0043679;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection terminus#GO:0044306;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;presynapse#GO:0098793;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000017503.1|UniProtKB=W5NLU9 W5NLU9 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016316.1|UniProtKB=W5NHN4 W5NHN4 PTHR23083:SF475 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT PROTEIN 7A phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;protein localization to plasma membrane#GO:0072659;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;organophosphate biosynthetic process#GO:0090407;localization#GO:0051179;localization within membrane#GO:0051668;phosphatidylinositol phosphate biosynthetic process#GO:0046854;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;intracellular protein localization#GO:0008104;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;protein localization to cell periphery#GO:1990778;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000017403.1|UniProtKB=W5NLJ9 W5NLJ9 PTHR35073:SF1 OTOSPIRALIN OTOSPIRALIN system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600 LEPOC|Ensembl=ENSLOCG00000018249.1|UniProtKB=W5NNZ1 W5NNZ1 PTHR11937:SF597 ACTIN ACTIN LIKE 7A structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Cadherin signaling pathway#P00012>F-actin#P00470;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858 LEPOC|Ensembl=ENSLOCG00000002510.1|UniProtKB=W5M3I7 W5M3I7 PTHR14096:SF34 APOLIPOPROTEIN L NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical structure#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000007250.1|UniProtKB=W5MK66 W5MK66 PTHR21231:SF7 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 3 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 G-protein#PC00020;protein-binding activity modulator#PC00095;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000003713.1|UniProtKB=W5M7Q6 W5M7Q6 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877;visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;multicellular organismal process#GO:0032501;sensory system development#GO:0048880 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010665.1|UniProtKB=W5MXG4 W5MXG4 PTHR10855:SF12 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 COP9 SIGNALOSOME COMPLEX SUBUNIT 4 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COP9 signalosome#GO:0008180;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear protein-containing complex#GO:0140513;cell junction#GO:0030054;nucleus#GO:0005634;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle#GO:0030133 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008619.1|UniProtKB=W5MQ20 W5MQ20 PTHR21064:SF1 AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED HYDROXYLYSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 LEPOC|Ensembl=ENSLOCG00000016107.1|UniProtKB=W5NGT7 W5NGT7 PTHR24366:SF120 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 4-RELATED immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000017769.1|UniProtKB=W5NML4 W5NML4 PTHR12561:SF3 LIPOATE-PROTEIN LIGASE LIPOYL AMIDOTRANSFERASE LIPT1, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004228.1|UniProtKB=W5M9K3 W5M9K3 PTHR10190:SF5 EYES ABSENT PROTEIN PHOSPHATASE EYA3 hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 developmental process#GO:0032502;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of DNA repair#GO:0045739;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;positive regulation of DNA metabolic process#GO:0051054;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000013179.1|UniProtKB=W5N6H6 W5N6H6 PTHR31164:SF1 RAD52 MOTIF-CONTAINING PROTEIN 1 RAD52 MOTIF-CONTAINING PROTEIN 1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011810.1|UniProtKB=W5N1L6 W5N1L6 PTHR24230:SF60 G-PROTEIN COUPLED RECEPTOR UROTENSIN-2 RECEPTOR molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014904.1|UniProtKB=W5NCJ5 W5NCJ5 PTHR16231:SF4 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000016053.1|UniProtKB=W5NGL9 W5NGL9 PTHR12098:SF4 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015766.1|UniProtKB=W5NFK0 W5NFK0 PTHR24099:SF21 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 67 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008043.1|UniProtKB=W5MN12 W5MN12 PTHR16008:SF4 F-BOX ONLY PROTEIN 4 F-BOX ONLY PROTEIN 4 cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000001766.1|UniProtKB=W5M0Z0 W5M0Z0 PTHR24300:SF319 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 1 binding#GO:0005488;tetrapyrrole binding#GO:0046906;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000000713.1|UniProtKB=W5LXD5 W5LXD5 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 519 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010496.1|UniProtKB=W5MWW2 W5MWW2 PTHR22811:SF184 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TMED10 PROTEIN vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010626.1|UniProtKB=W5MXA2 W5MXA2 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 LEPOC|Ensembl=ENSLOCG00000008838.1|UniProtKB=W5MQW5 W5MQW5 PTHR12582:SF6 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 LEPOC|Ensembl=ENSLOCG00000005284.1|UniProtKB=W5MDA5 W5MDA5 PTHR12788:SF4 PROTEIN-TYROSINE SULFOTRANSFERASE 2 PROTEIN-TYROSINE SULFOTRANSFERASE 1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220 CCKR signaling map#P06959>Protein tyrosine sulfotransferase#P07148 LEPOC|Ensembl=ENSLOCG00000001281.1|UniProtKB=W5LZC6 W5LZC6 PTHR21224:SF1 INTEGRATOR COMPLEX SUBUNIT 1 INTEGRATOR COMPLEX SUBUNIT 1 transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;DNA-templated transcription#GO:0006351;catabolic process#GO:0009056;DNA-templated transcription initiation#GO:0006352 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;integrator complex#GO:0032039;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000002617.1|UniProtKB=W5M3X0 W5M3X0 PTHR10263:SF18 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 21 KDA PROTEOLIPID SUBUNIT C'' cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000001209.1|UniProtKB=W5LZ10 W5LZ10 PTHR23113:SF167 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS1 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000003273.1|UniProtKB=W5M667 W5M667 PTHR12786:SF2 SPLICING FACTOR SF3A-RELATED SPLICING FACTOR 3A SUBUNIT 3 binding#GO:0005488;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 nucleus#GO:0005634;spliceosomal complex#GO:0005681;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;U2 snRNP#GO:0005686;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000000689.1|UniProtKB=W5LXB0 W5LXB0 PTHR11690:SF13 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 4 sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007643.1|UniProtKB=W5MLL1 W5MLL1 PTHR21603:SF17 ANTIGEN KI-67-LIKE PROTEIN PROLIFERATION MARKER PROTEIN KI-67 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;molecular condensate scaffold activity#GO:0140693 sexual reproduction#GO:0019953;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;reproductive process#GO:0022414;cell cycle#GO:0007049;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of mitotic nuclear division#GO:0007088;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987 chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000011861.1|UniProtKB=W5N1S8 W5N1S8 PTHR12280:SF21 PANTOTHENATE KINASE PANTOTHENATE KINASE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase#PC00137;metabolite interconversion enzyme#PC00262 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 LEPOC|Ensembl=ENSLOCG00000005631.1|UniProtKB=W5MEI5 W5MEI5 PTHR45704:SF8 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE LEPOC|Ensembl=ENSLOCG00000018295.1|UniProtKB=W5NP37 W5NP37 PTHR11829:SF361 FORKHEAD BOX PROTEIN FORKHEAD BOX D2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000004474.1|UniProtKB=W5MAE7 W5MAE7 PTHR46180:SF1 VINCULIN VINCULIN protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488 cellular process#GO:0009987;cell adhesion#GO:0007155 intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;organelle#GO:0043226;cellular anatomical structure#GO:0110165;adherens junction#GO:0005912;cell-cell contact zone#GO:0044291;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 Gonadotropin-releasing hormone receptor pathway#P06664>Vinculin#P06771;Integrin signalling pathway#P00034>Vinculin#P00937 LEPOC|Ensembl=ENSLOCG00000003906.1|UniProtKB=W5M8F3 W5M8F3 PTHR45615:SF26 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-15 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000016254.1|UniProtKB=W5NHD6 W5NHD6 PTHR11267:SF20 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX18 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cell fate commitment#GO:0045165;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;morphogenesis of an epithelium#GO:0002009;anatomical structure formation involved in morphogenesis#GO:0048646;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;cell fate specification#GO:0001708;anterior/posterior pattern specification#GO:0009952;embryo development#GO:0009790;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 LEPOC|Ensembl=ENSLOCG00000007680.1|UniProtKB=W5MLR4 W5MLR4 PTHR10715:SF0 60S RIBOSOMAL PROTEIN L6 LARGE RIBOSOMAL SUBUNIT PROTEIN EL6 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000012278.1|UniProtKB=W5N3A1 W5N3A1 PTHR46628:SF1 PIRNA BIOGENESIS PROTEIN EXD1 PIRNA BIOGENESIS PROTEIN EXD1 RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;piRNA processing#GO:0034587;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000013654.1|UniProtKB=W5N876 W5N876 PTHR24231:SF52 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CYSTEINYL LEUKOTRIENE RECEPTOR 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010558.1|UniProtKB=W5MX30 W5MX30 UGT1A1 PTHR48050:SF31 STEROL 3-BETA-GLUCOSYLTRANSFERASE GLUCURONOSYLTRANSFERASE binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;catalytic activity#GO:0003824;transferase activity#GO:0016740;enzyme inhibitor activity#GO:0004857;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;molecular function regulator activity#GO:0098772 cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008;response to endogenous stimulus#GO:0009719;regulation of hormone levels#GO:0010817;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;liver development#GO:0001889;metabolic process#GO:0008152;multicellular organism development#GO:0007275;cellular response to steroid hormone stimulus#GO:0071383;animal organ development#GO:0048513;response to hormone#GO:0009725;cellular process#GO:0009987;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;steroid metabolic process#GO:0008202;response to steroid hormone#GO:0048545;anatomical structure development#GO:0048856;system development#GO:0048731;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;developmental process#GO:0032502;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125;pigment metabolic process#GO:0042440;hormone metabolic process#GO:0042445;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000002527.1|UniProtKB=W5M3L3 W5M3L3 PTHR11035:SF17 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 2 catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000007941.1|UniProtKB=W5MMP4 W5MMP4 PTHR11573:SF6 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT binding#GO:0005488;anion binding#GO:0043168;ATP binding#GO:0005524;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367 biosynthetic process#GO:0009058;cellular process#GO:0009987;metabolic process#GO:0008152 oxidoreductase complex#GO:1990204;cytosol#GO:0005829;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo purine biosynthesis#P02738>GDP reductase#P02909;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921 LEPOC|Ensembl=ENSLOCG00000012030.1|UniProtKB=W5N2D9 W5N2D9 PTHR22948:SF4 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 1 negative regulation of metabolic process#GO:0009892;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cell differentiation#GO:0030154;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;oogenesis#GO:0048477;embryo development#GO:0009790;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;embryonic pattern specification#GO:0009880;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anterior/posterior axis specification#GO:0009948;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;anterior/posterior pattern specification#GO:0009952;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;pattern specification process#GO:0007389;piRNA processing#GO:0034587;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;male gamete generation#GO:0048232;regionalization#GO:0003002;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;cell maturation#GO:0048469;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000524.1|UniProtKB=W5LWR9 W5LWR9 PTHR10339:SF32 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 5-RELATED glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007123.1|UniProtKB=W5MJR3 W5MJR3 PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN SENTAN calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000007224.1|UniProtKB=W5MK32 W5MK32 PTHR46771:SF2 DETERIN BACULOVIRAL IAP REPEAT-CONTAINING 5B cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;microtubule cytoskeleton organization#GO:0000226;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell division#GO:0051301;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;negative regulation of cellular process#GO:0048523;chromosome segregation#GO:0007059;regulation of apoptotic process#GO:0042981;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;organelle organization#GO:0006996;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;membraneless organelle#GO:0043228;spindle#GO:0005819;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779 Angiogenesis#P00005>Survivin#P00198 LEPOC|Ensembl=ENSLOCG00000010614.1|UniProtKB=W5MX94 W5MX94 PTHR24028:SF0 CADHERIN-87A PROTOCADHERIN-10 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000006643.1|UniProtKB=W5MI18 W5MI18 PTHR11811:SF25 6-PHOSPHOGLUCONATE DEHYDROGENASE 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING phosphogluconate dehydrogenase (decarboxylating) activity#GO:0004616;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;generation of precursor metabolites and energy#GO:0006091;pentose-phosphate shunt, oxidative branch#GO:0009051;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 Pentose phosphate pathway#P02762>Gluconate Dehydrogenase#P03070 LEPOC|Ensembl=ENSLOCG00000006596.1|UniProtKB=W5MHW3 W5MHW3 PTHR23344:SF13 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 6 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 membrane#GO:0016020;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000014854.1|UniProtKB=W5NCD3 W5NCD3 PTHR14166:SF16 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 4 enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;system development#GO:0048731;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;regulation of cell migration#GO:0030334;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;GTPase-activating protein#PC00257 CCKR signaling map#P06959>ARHGAP4#P07135;PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000004860.1|UniProtKB=W5MBV0 W5MBV0 PTHR10894:SF0 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 56 binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;RNA binding#GO:0003723 ribonucleoprotein complex#GO:1990904;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015303.1|UniProtKB=W5NDX2 W5NDX2 PTHR11972:SF203 NADPH OXIDASE NADPH OXIDASE 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 superoxide metabolic process#GO:0006801;response to stimulus#GO:0050896;defense response#GO:0006952;metabolic process#GO:0008152;response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000012704.1|UniProtKB=W5N4U2 W5N4U2 PTHR21704:SF19 NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED NIPPED-B-LIKE PROTEIN binding#GO:0005488;chromatin binding#GO:0003682 system development#GO:0048731;localization#GO:0051179;anatomical structure development#GO:0048856;sister chromatid cohesion#GO:0007062;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;recombinational repair#GO:0000725;mitotic cell cycle#GO:0000278;animal organ morphogenesis#GO:0009887;heart morphogenesis#GO:0003007;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;DNA damage response#GO:0006974;developmental process#GO:0032502;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;tube development#GO:0035295;mitotic sister chromatid cohesion#GO:0007064;brain development#GO:0007420;multicellular organismal process#GO:0032501;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;skeletal system morphogenesis#GO:0048705;skeletal system development#GO:0001501;cellular response to stress#GO:0033554;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;response to stimulus#GO:0050896;circulatory system development#GO:0072359;central nervous system development#GO:0007417;anatomical structure morphogenesis#GO:0009653;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;cellular component organization#GO:0016043;double-strand break repair#GO:0006302;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nervous system development#GO:0007399;embryo development#GO:0009790;head development#GO:0060322;heart development#GO:0007507;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009307.1|UniProtKB=W5MSK6 W5MSK6 PTHR14304:SF14 CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000007324.1|UniProtKB=W5MKG8 W5MKG8 PTHR22704:SF1 BMERB DOMAIN-CONTAINING PROTEIN 1-RELATED BMERB DOMAIN-CONTAINING PROTEIN 1 negative regulation of biological process#GO:0048519;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of microtubule-based process#GO:0032886;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of protein-containing complex disassembly#GO:0043244;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein depolymerization#GO:1901880;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000017884.1|UniProtKB=W5NMX8 W5NMX8 PTHR24249:SF417 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 11 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012449.1|UniProtKB=W5N3W6 W5N3W6 ACOT6 PTHR10824:SF42 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COA THIOESTERASE 20-RELATED hydrolase activity#GO:0016787;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790 nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;oxoacid metabolic process#GO:0043436;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000016929.1|UniProtKB=W5NJX0 W5NJX0 PTHR11629:SF26 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 4 protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;enzyme binding#GO:0019899;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 homeostatic process#GO:0042592;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transmembrane transport#GO:0034220;macroautophagy#GO:0016236;biological regulation#GO:0065007;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;autophagosome maturation#GO:0097352;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;proton transmembrane transport#GO:1902600;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;transmembrane transport#GO:0055085;cellular process#GO:0009987;autophagy#GO:0006914;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;brush border membrane#GO:0031526;cytoplasm#GO:0005737;vacuole#GO:0005773;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;cell projection membrane#GO:0031253;ATPase dependent transmembrane transport complex#GO:0098533;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;brush border#GO:0005903;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;apical plasma membrane#GO:0016324;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000010300.1|UniProtKB=W5MW56 W5MW56 PTHR14716:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69 regulation of microtubule-based process#GO:0032886;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of reproductive process#GO:2000241;response to stimulus#GO:0050896;regulation of microtubule-based movement#GO:0060632;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;9+2 motile cilium#GO:0097729;cilium#GO:0005929;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009496.1|UniProtKB=W5MT91 W5MT91 PTHR23048:SF44 MYOSIN LIGHT CHAIN 1, 3 ATRIAL MYOSIN LIGHT CHAIN catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;structural molecule activity#GO:0005198;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657 actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000008291.1|UniProtKB=W5MNW0 W5MNW0 PTHR22957:SF324 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN CARABIN GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000017425.1|UniProtKB=W5NLM1 W5NLM1 PTHR20994:SF0 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;macroautophagy#GO:0016236;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organelle assembly#GO:0070925;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 LEPOC|Ensembl=ENSLOCG00000011429.1|UniProtKB=W5N090 W5N090 PTHR45662:SF8 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITIDE 4-PHOSPHATASE SAC2 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;lipid modification#GO:0030258;regulation of localization#GO:0032879;regulation of transport#GO:0051049;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;phosphatidylinositol dephosphorylation#GO:0046856;dephosphorylation#GO:0016311;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle#GO:0030136;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;early endosome#GO:0005769;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004708.1|UniProtKB=W5MB93 W5MB93 PTHR12442:SF11 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cell projection assembly#GO:0030031;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium movement#GO:0003341;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003 cytoskeleton#GO:0005856;outer dynein arm#GO:0036157;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;catalytic complex#GO:1902494;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005505.1|UniProtKB=W5ME34 W5ME34 PTHR24412:SF398 KELCH PROTEIN KELCH-LIKE PROTEIN 30 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011705.1|UniProtKB=W5N182 W5N182 PTHR23423:SF28 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184B transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007644.1|UniProtKB=W5MLL8 W5MLL8 PTHR24121:SF24 NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED ION CHANNEL NOMPC LEPOC|Ensembl=ENSLOCG00000003625.1|UniProtKB=W5M7E2 W5M7E2 PTHR45944:SF5 SCHNURRI, ISOFORM F TRANSCRIPTION FACTOR HIVEP3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015012.1|UniProtKB=W5NCY3 W5NCY3 PTHR11528:SF144 HEAT SHOCK PROTEIN 90 FAMILY MEMBER ENDOPLASMIN ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein folding#GO:0006457;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Hsp90 family chaperone#PC00028;chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009958.1|UniProtKB=W5MUX1 W5MUX1 PTHR46012:SF1 IP22168P GLUCOSIDE XYLOSYLTRANSFERASE 2 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 LEPOC|Ensembl=ENSLOCG00000002584.1|UniProtKB=W5M3T0 W5M3T0 PTHR24412:SF232 KELCH PROTEIN GIGAXONIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010339.1|UniProtKB=W5MWA9 W5MWA9 PTHR47006:SF1 STAR-RELATED LIPID TRANSFER PROTEIN 4 STAR-RELATED LIPID TRANSFER PROTEIN 4 alcohol binding#GO:0043178;cholesterol transfer activity#GO:0120020;steroid binding#GO:0005496;transporter activity#GO:0005215;sterol transfer activity#GO:0120015;lipid transfer activity#GO:0120013;cholesterol binding#GO:0015485;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094;molecular carrier activity#GO:0140104;sterol binding#GO:0032934;lipid carrier activity#GO:0005319 organic hydroxy compound transport#GO:0015850;localization#GO:0051179;establishment of localization#GO:0051234;sterol transport#GO:0015918;cellular localization#GO:0051641;transport#GO:0006810;lipid localization#GO:0010876;intracellular transport#GO:0046907;intracellular sterol transport#GO:0032366;lipid transport#GO:0006869;establishment of localization in cell#GO:0051649;lipid storage#GO:0019915;cellular process#GO:0009987;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000014452.1|UniProtKB=W5NAX8 W5NAX8 PTHR46961:SF11 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN DYNEIN HEAVY CHAIN LINKER DOMAIN-CONTAINING PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016265.1|UniProtKB=W5NHF6 W5NHF6 PTHR15414:SF0 OS-9-RELATED ENDOPLASMIC RETICULUM LECTIN 1 intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;biological regulation#GO:0065007;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;localization#GO:0051179;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;cellular localization#GO:0051641;response to unfolded protein#GO:0006986;regulation of biological process#GO:0050789;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788 LEPOC|Ensembl=ENSLOCG00000012657.1|UniProtKB=W5N4M1 W5N4M1 PTHR28658:SF3 TRANSMEMBRANE PROTEIN 180 SOLUTE CARRIER FAMILY 68 MEMBER 1 LEPOC|Ensembl=ENSLOCG00000015697.1|UniProtKB=W5NFB2 W5NFB2 PTHR16095:SF9 TRANSMEMBRANE PROTEIN 143 FAMILY MEMBER PROLINE AND SERINE-RICH PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000012413.1|UniProtKB=W5N3T5 W5N3T5 PTHR24169:SF21 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P100 SUBUNIT sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;response to other organism#GO:0051707;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;canonical NF-kappaB signal transduction#GO:0007249;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;positive regulation of RNA metabolic process#GO:0051254;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;positive regulation of transcription by RNA polymerase II#GO:0045944;intracellular signaling cassette#GO:0141124;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;non-canonical NF-kappaB signal transduction#GO:0038061;signal transduction#GO:0007165;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to peptide#GO:1901652;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;B cell activation#P00010>NFkappaB#P00370;Apoptosis signaling pathway#P00006>NFkappaB#P00297;Toll receptor signaling pathway#P00054>NFkappaB#P01354;T cell activation#P00053>NFkappaB#P01298 LEPOC|Ensembl=ENSLOCG00000011849.1|UniProtKB=W5N1R0 W5N1R0 PTHR32261:SF2 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 1 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000011746.1|UniProtKB=W5N1D3 W5N1D3 PTHR24206:SF95 OS06G0237300 PROTEIN CYTOSKELETON-ASSOCIATED LIM DOMAIN PROTEIN-RELATED actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000012769.1|UniProtKB=W5N504 W5N504 PTHR12598:SF0 COPPER HOMEOSTASIS PROTEIN CUTC COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;copper ion binding#GO:0005507;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000017784.1|UniProtKB=W5NMM9 W5NMM9 PTHR24231:SF15 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 2-OXOGLUTARATE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000005.1|UniProtKB=W5LV48 W5LV48 PTHR23326:SF34 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013 intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;CCR4-NOT complex#GO:0030014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000004588.1|UniProtKB=W5MAV3 W5MAV3 PTHR21207:SF7 PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED PARKIN COREGULATED GENE PROTEIN protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cytosol#GO:0005829;neuron projection#GO:0043005;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000013685.1|UniProtKB=W5N8B2 W5N8B2 PTHR46491:SF3 CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 LEPOC|Ensembl=ENSLOCG00000012605.1|UniProtKB=W5N4F8 W5N4F8 PTHR12738:SF0 NEUROENDOCRINE PROTEIN 7B2 NEUROENDOCRINE PROTEIN 7B2 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015603.1|UniProtKB=W5NF00 W5NF00 PTHR24211:SF1 LIM DOMAIN-CONTAINING PROTEIN TESTIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013974.1|UniProtKB=W5N9C6 W5N9C6 PTHR23257:SF763 SERINE-THREONINE PROTEIN KINASE RAF PROTO-ONCOGENE SERINE_THREONINE-PROTEIN KINASE protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000014516.1|UniProtKB=W5NB58 W5NB58 PTHR22988:SF79 MYOTONIC DYSTROPHY S/T KINASE-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000004871.1|UniProtKB=W5MBV1 W5MBV1 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER PANCREATIC ELASTASE catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006845.1|UniProtKB=W5MIT2 W5MIT2 PTHR23220:SF22 INTEGRIN ALPHA INTEGRIN ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154 protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;signaling receptor complex#GO:0043235;integrin complex#GO:0008305 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941;Gonadotropin-releasing hormone receptor pathway#P06664>alpha-beta integrin dimer#P06820 LEPOC|Ensembl=ENSLOCG00000008959.1|UniProtKB=W5MRA2 W5MRA2 PTHR24409:SF298 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 142 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000004832.1|UniProtKB=W5MBP5 W5MBP5 PTHR43157:SF30 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED ZGC:64106 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009875.1|UniProtKB=W5MUL0 W5MUL0 PTHR24110:SF3 CENTROSOMAL PROTEIN OF 78 KDA CENTROSOMAL PROTEIN OF 78 KDA cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;cilium organization#GO:0044782;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000011524.1|UniProtKB=W5N0N4 W5N0N4 PTHR45703:SF41 DYNEIN HEAVY CHAIN CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000009914.1|UniProtKB=W5MUR5 W5MUR5 PTHR10037:SF301 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 membrane depolarization#GO:0051899;metal ion transport#GO:0030001;sensory perception of pain#GO:0019233;action potential#GO:0001508;sodium ion transport#GO:0006814;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;system process#GO:0003008;transport#GO:0006810 transporter complex#GO:1990351;cation channel complex#GO:0034703;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000013187.1|UniProtKB=W5N6I5 W5N6I5 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000010635.1|UniProtKB=W5MXB2 W5MXB2 PTHR11848:SF19 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 9 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000002419.1|UniProtKB=W5M386 W5M386 PTHR18853:SF7 FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000005748.1|UniProtKB=W5MEY7 W5MEY7 PTHR13140:SF381 MYOSIN UNCONVENTIONAL MYOSIN-IG isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544 endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based movement#GO:0030048;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;transport#GO:0006810;actin filament-based process#GO:0030029 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000017207.1|UniProtKB=W5NKW5 W5NKW5 PTHR23339:SF26 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000015315.1|UniProtKB=W5NDY5 W5NDY5 PTHR23349:SF57 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FACTOR IN THE GERMLINE ALPHA transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000005842.1|UniProtKB=W5MF92 W5MF92 PTHR13476:SF0 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000006482.1|UniProtKB=W5MHH0 W5MHH0 PTHR11558:SF11 SPERMIDINE/SPERMINE SYNTHASE SPERMIDINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000000138.1|UniProtKB=W5LVJ6 W5LVJ6 PTHR17901:SF14 MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1 MAGNESIUM-DEPENDENT PHOSPHATASE 1 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001783.1|UniProtKB=W5M175 W5M175 PTHR24202:SF53 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB1 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 establishment of localization#GO:0051234;Notch signaling pathway#GO:0007219;import into cell#GO:0098657;macromolecule metabolic process#GO:0043170;transport#GO:0006810;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;cellular process#GO:0009987;signal transduction#GO:0007165;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;localization#GO:0051179;cell communication#GO:0007154;protein modification by small protein conjugation or removal#GO:0070647;signaling#GO:0023052;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006993.1|UniProtKB=W5MJA4 W5MJA4 PTHR18966:SF100 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 4 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 synaptic membrane#GO:0097060;transporter complex#GO:1990351;cell junction#GO:0030054;neuron projection#GO:0043005;protein-containing complex#GO:0032991;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynapse#GO:0098794;dendritic spine#GO:0043197;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;neuron spine#GO:0044309;cell projection#GO:0042995;signaling receptor complex#GO:0043235;membrane#GO:0016020;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu4#P01015;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019 LEPOC|Ensembl=ENSLOCG00000009042.1|UniProtKB=W5MRL7 W5MRL7 PTHR11353:SF19 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT THETA ISOFORM X1 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000000008.1|UniProtKB=W5LV50 W5LV50 PTHR19282:SF40 TETRASPANIN TETRASPANIN-4 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003288.1|UniProtKB=W5M676 W5M676 PTHR11349:SF49 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE D, MITOCHONDRIAL catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776 nucleoside triphosphate metabolic process#GO:0009141;biosynthetic process#GO:0009058;cellular process#GO:0009987;nucleoside triphosphate biosynthetic process#GO:0009142;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137;transferase#PC00220 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912;De novo purine biosynthesis#P02738>GDP kinase#P02891;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 LEPOC|Ensembl=ENSLOCG00000007492.1|UniProtKB=W5ML36 W5ML36 PTHR24034:SF137 EGF-LIKE DOMAIN-CONTAINING PROTEIN SI:DKEY-163F14.6 transforming growth factor beta binding#GO:0050431;binding#GO:0005488;cytokine binding#GO:0019955;growth factor binding#GO:0019838;protein binding#GO:0005515 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000000359.1|UniProtKB=W5LW86 W5LW86 PTHR45134:SF5 OS08G0543275 PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000103.1|UniProtKB=W5LVG2 W5LVG2 PTHR23339:SF77 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14A hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;cell projection assembly#GO:0030031;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;positive regulation of cell cycle#GO:0045787;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;organelle assembly#GO:0070925;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030 microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000013180.1|UniProtKB=W5N6I0 W5N6I0 PTHR13284:SF10 GH01354P SELENOCYSTEINE INSERTION SEQUENCE-BINDING PROTEIN 2-LIKE RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;mRNA 3'-UTR binding#GO:0003730;protein-containing complex binding#GO:0044877;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000010727.1|UniProtKB=W5MXP8 W5MXP8 PTHR44663:SF2 JUNCTIONAL ADHESION MOLECULE B JUNCTIONAL ADHESION MOLECULE B cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001044.1|UniProtKB=W5LYG6 W5LYG6 PTHR11127:SF2 60S RIBOSOMAL PROTEIN L14 LARGE RIBOSOMAL SUBUNIT PROTEIN EL14 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000012401.1|UniProtKB=W5N3Q9 W5N3Q9 PTHR11592:SF36 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 2 catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000014674.1|UniProtKB=W5NBR2 W5NBR2 PTHR46513:SF44 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 4 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014020.1|UniProtKB=W5N9H7 W5N9H7 PTHR43884:SF9 ACYL-COA DEHYDROGENASE COMPLEX I ASSEMBLY FACTOR ACAD9, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000009588.1|UniProtKB=W5MTK7 W5MTK7 PTHR10253:SF12 POLYCOMB PROTEIN POLYCOMB PROTEIN EED molecular function activator activity#GO:0140677;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;chromatin binding#GO:0003682;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014751.1|UniProtKB=W5NC02 W5NC02 PTHR31800:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000004915.1|UniProtKB=W5MC03 W5MC03 PTHR19860:SF16 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 12 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 LEPOC|Ensembl=ENSLOCG00000003950.1|UniProtKB=W5M8K7 W5M8K7 PTHR10605:SF11 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000018.1|UniProtKB=W5LV62 W5LV62 PTHR11481:SF132 IMMUNOGLOBULIN FC RECEPTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune response#GO:0006955;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376;cell communication#GO:0007154 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005374.1|UniProtKB=W5MDL8 W5MDL8 PTHR45822:SF8 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 3 ISOFORM X2-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to fatty acid#GO:0070542;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to fatty acid#GO:0071398;biological regulation#GO:0065007;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015233.1|UniProtKB=W5NDN8 W5NDN8 PTHR18884:SF55 SEPTIN SEPTIN-6 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 cell cycle#GO:0007049;macromolecule localization#GO:0033036;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;intracellular protein localization#GO:0008104;cytokinesis#GO:0000910 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006562.1|UniProtKB=W5MHR8 W5MHR8 PTHR48036:SF6 SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED RNA-BINDING MOTIF PROTEIN 39A-RELATED binding#GO:0005488;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000006369.1|UniProtKB=W5MH44 W5MH44 PTHR10574:SF240 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-3 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;multicellular organismal process#GO:0032501 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000011866.1|UniProtKB=W5N1T5 W5N1T5 PTHR22981:SF85 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED 3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000012553.1|UniProtKB=W5N4A6 W5N4A6 PTHR10217:SF630 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED DELAYED RECTIFIER POTASSIUM CHANNEL KCNH4 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 cellular process#GO:0009987;potassium ion transport#GO:0006813;biological regulation#GO:0065007;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000005068.1|UniProtKB=W5MCJ9 W5MCJ9 PTHR23339:SF96 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PALADIN phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007190.1|UniProtKB=W5MK00 W5MK00 PTHR22166:SF12 ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum tubular network organization#GO:0071786;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum tubular network#GO:0071782 LEPOC|Ensembl=ENSLOCG00000008630.1|UniProtKB=W5MQ51 W5MQ51 PTHR46877:SF6 EPH RECEPTOR A5 EPHRIN TYPE-B RECEPTOR 3 transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 LEPOC|Ensembl=ENSLOCG00000008782.1|UniProtKB=W5MQN3 W5MQN3 PTHR15459:SF3 POLYAMINE-MODULATED FACTOR 1 POLYAMINE-MODULATED FACTOR 1 chromosome segregation#GO:0007059;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049 chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779 LEPOC|Ensembl=ENSLOCG00000015083.1|UniProtKB=W5ND59 W5ND59 PTHR43340:SF12 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;pentosyltransferase activity#GO:0016763;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase metabolic process#GO:0006144;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245;Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804 LEPOC|Ensembl=ENSLOCG00000002702.1|UniProtKB=W5M467 W5M467 PTHR13180:SF4 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50A vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659 LEPOC|Ensembl=ENSLOCG00000016219.1|UniProtKB=W5NH93 W5NH93 PTHR46957:SF2 CYTOKINE RECEPTOR RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE BETA binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;system development#GO:0048731;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;tube development#GO:0035295;multicellular organismal process#GO:0032501;circulatory system development#GO:0072359 protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VE-PTP#P00250 LEPOC|Ensembl=ENSLOCG00000007736.1|UniProtKB=W5MLY2 W5MLY2 PTHR38663:SF1 FAMILY NOT NAMED L-ORNITHINE N(5)-MONOOXYGENASE LEPOC|Ensembl=ENSLOCG00000009737.1|UniProtKB=W5MU43 W5MU43 PTHR10336:SF210 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-1 glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lipase#PC00143;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484 LEPOC|Ensembl=ENSLOCG00000017937.1|UniProtKB=W5NN31 W5NN31 PTHR15570:SF2 G0/G1 SWITCH PROTEIN 2 G0_G1 SWITCH PROTEIN 2 cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;regulation of response to stimulus#GO:0048583;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;apoptotic signaling pathway#GO:0097190;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016634.1|UniProtKB=W5NIT8 W5NIT8 PTHR21583:SF8 ELYS PROTEIN PROTEIN ELYS scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015087.1|UniProtKB=W5ND61 W5ND61 PTHR22884:SF473 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008802.1|UniProtKB=W5MQQ5 W5MQQ5 PTHR13924:SF11 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 2 nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;binding#GO:0005488;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297 developmental process#GO:0032502;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;spindle organization#GO:0007051;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;system development#GO:0048731;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;nuclear migration#GO:0007097;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell differentiation#GO:0030154;cytoplasmic microtubule organization#GO:0031122;establishment of organelle localization#GO:0051656 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000005701.1|UniProtKB=W5MES6 W5MES6 PTHR23068:SF9 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3B DNA binding#GO:0003677;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on DNA#GO:0140097;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA methyltransferase#PC00013 LEPOC|Ensembl=ENSLOCG00000017095.1|UniProtKB=W5NKH3 W5NKH3 AKR1B1 PTHR11732:SF294 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014077.1|UniProtKB=W5N9P1 W5N9P1 PTHR31054:SF6 ZYGOTE ARREST PROTEIN 1-LIKE ISOFORM X1 ZYGOTE ARREST PROTEIN 1 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;developmental maturation#GO:0021700;developmental process#GO:0032502;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cell maturation#GO:0048469;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;developmental process involved in reproduction#GO:0003006;negative regulation of protein metabolic process#GO:0051248;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;oogenesis#GO:0048477;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;cell differentiation#GO:0030154;negative regulation of translation#GO:0017148 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000007979.1|UniProtKB=W5MMW4 W5MMW4 PTHR46961:SF13 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN DYNEIN HEAVY CHAIN, CYTOPLASMIC-LIKE PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000018046.1|UniProtKB=W5NND8 W5NND8 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR-RELATED binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012172.1|UniProtKB=W5N2X2 W5N2X2 ALDH18A1 PTHR11063:SF28 GLUTAMATE SEMIALDEHYDE DEHYDROGENASE DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001533.1|UniProtKB=W5M045 W5M045 PTHR10343:SF96 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1 kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 LEPOC|Ensembl=ENSLOCG00000001657.1|UniProtKB=W5M0K3 W5M0K3 PTHR24160:SF1 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 53 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 53 mitotic cell cycle process#GO:1903047;regulation of microtubule polymerization or depolymerization#GO:0031110;chromosome organization#GO:0051276;positive regulation of protein polymerization#GO:0032273;biological regulation#GO:0065007;mitotic sister chromatid segregation#GO:0000070;positive regulation of cellular process#GO:0048522;regulation of mitotic cytokinesis#GO:1902412;localization#GO:0051179;organelle fission#GO:0048285;regulation of cell division#GO:0051302;organelle localization#GO:0051640;regulation of microtubule-based process#GO:0032886;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;regulation of spindle organization#GO:0090224;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;regulation of supramolecular fiber organization#GO:1902903;mitotic metaphase chromosome alignment#GO:0007080;cellular component organization or biogenesis#GO:0071840;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell cycle process#GO:0010564;chromosome localization#GO:0050000;regulation of microtubule cytoskeleton organization#GO:0070507;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of organelle organization#GO:0010638;regulation of mitotic spindle organization#GO:0060236;regulation of microtubule polymerization#GO:0031113;regulation of cytokinesis#GO:0032465;nuclear division#GO:0000280;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;sister chromatid segregation#GO:0000819;regulation of protein-containing complex assembly#GO:0043254;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015500.1|UniProtKB=W5NEL8 W5NEL8 PTHR11726:SF10 60S RIBOSOMAL PROTEIN L10 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016276.1|UniProtKB=W5NHH0 W5NHH0 PTHR15036:SF51 PIKACHURIN-LIKE PROTEIN NEUREXIN-1 signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor binding#GO:0005102 developmental process#GO:0032502;intracellular protein localization#GO:0008104;system process#GO:0003008;macromolecule localization#GO:0033036;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;protein localization to cell junction#GO:1902414;organelle assembly#GO:0070925;cognition#GO:0050890;synapse organization#GO:0050808;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;postsynaptic specialization organization#GO:0099084;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;postsynapse organization#GO:0099173;protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;postsynaptic density assembly#GO:0097107;cellular process#GO:0009987;cellular component assembly#GO:0022607;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;nervous system process#GO:0050877;postsynaptic density organization#GO:0097106;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;synapse assembly#GO:0007416;signaling#GO:0023052;excitatory synapse assembly#GO:1904861 plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;presynapse#GO:0098793;cell periphery#GO:0071944;presynaptic active zone membrane#GO:0048787;membrane#GO:0016020;cell junction#GO:0030054;presynaptic active zone#GO:0048786;synaptic membrane#GO:0097060 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015700.1|UniProtKB=W5NFC1 W5NFC1 FEZ2 PTHR12394:SF11 ZYGIN FASCICULATION AND ELONGATION PROTEIN ZETA-2 neuron projection#GO:0043005;axon#GO:0030424;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000004471.1|UniProtKB=W5MAD6 W5MAD6 PTHR14709:SF2 GLUTAMINE AND SERINE-RICH PROTEIN 1-RELATED GLUTAMINE AND SERINE-RICH PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000012616.1|UniProtKB=W5N4H4 W5N4H4 PTHR22834:SF17 NUCLEAR FUSION PROTEIN FUS2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 38 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000010485.1|UniProtKB=W5MWU2 W5MWU2 PTHR11158:SF20 MSF1/PX19 RELATED PRELI DOMAIN-CONTAINING PROTEIN 2 lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 transport#GO:0006810;lipid localization#GO:0010876;localization#GO:0051179;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000008696.1|UniProtKB=W5MQC2 W5MQC2 PTHR10264:SF87 BAND 7 PROTEIN-RELATED STOMATIN (EPB72)-LIKE 3A-RELATED molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transporter regulator activity#GO:0141108 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010179.1|UniProtKB=W5MVQ3 W5MVQ3 PTHR11860:SF87 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CD300 MOLECULE LIKE FAMILY MEMBER G-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003698.1|UniProtKB=W5M7P5 W5M7P5 PTHR24043:SF5 SCAVENGER RECEPTOR CLASS F SCAVENGER RECEPTOR CLASS F MEMBER 2 cargo receptor activity#GO:0038024 cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016979.1|UniProtKB=W5NK30 W5NK30 PTHR10574:SF450 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-4 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;tissue development#GO:0009888;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000005805.1|UniProtKB=W5MF53 W5MF53 PTHR31488:SF4 DPY-19-LIKE 1, LIKE (H. SAPIENS) PROTEIN C-MANNOSYL-TRANSFERASE DPY19L3 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000005166.1|UniProtKB=W5MCW5 W5MCW5 PTHR24072:SF99 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOF nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001 cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cell migration#GO:0016477;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154 cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017372.1|UniProtKB=W5NLG8 W5NLG8 PTHR41161:SF1 PROTEIN NCBP2AS2 PROTEIN NCBP2AS2 LEPOC|Ensembl=ENSLOCG00000005792.1|UniProtKB=W5MF58 W5MF58 PTHR22811:SF50 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;cellular component organization#GO:0016043;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179 endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005675.1|UniProtKB=W5MEP8 W5MEP8 PTHR24248:SF118 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE RECEPTOR D2 LIKE ISOFORM X1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;neurotransmitter receptor activity#GO:0030594 biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;G protein-coupled dopamine receptor signaling pathway#GO:0007212;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;negative regulation of cellular process#GO:0048523;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;adrenergic receptor signaling pathway#GO:0071875;negative regulation of cell communication#GO:0010648;response to nitrogen compound#GO:1901698;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;negative regulation of signaling#GO:0023057;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887 cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;cell junction#GO:0030054 G-protein coupled receptor#PC00021 Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965 LEPOC|Ensembl=ENSLOCG00000004924.1|UniProtKB=W5MC12 W5MC12 PTHR24027:SF450 CADHERIN-23 B-CADHERIN ISOFORM X1-RELATED binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cell motility#GO:0048870;cell migration#GO:0016477;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;intracellular anatomical structure#GO:0005622 cell adhesion molecule#PC00069;cadherin#PC00057 Alzheimer disease-presenilin pathway#P00004>E-cadherin C-terminal fragment#P00117;Cadherin signaling pathway#P00012>Cadherin#P00471;Alzheimer disease-presenilin pathway#P00004>E-cadherin N-terminal fragment#P00165;Alzheimer disease-presenilin pathway#P00004>E-cadherin transmembrane fragment#P00139;Wnt signaling pathway#P00057>Cadherin#P01440;Alzheimer disease-presenilin pathway#P00004>E-cadherin#P00118;Alzheimer disease-presenilin pathway#P00004>E-cadherin intracellular fragment#P00168 LEPOC|Ensembl=ENSLOCG00000011144.1|UniProtKB=W5MZ83 W5MZ83 PTHR23049:SF79 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN, LIGHT CHAIN 12, GENOME DUPLICATE 1-RELATED cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488;protein binding#GO:0005515 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000008705.1|UniProtKB=W5MQD6 W5MQD6 PTHR13455:SF4 TRANSCRIPTIONAL REPRESSOR P66-RELATED TRANSCRIPTIONAL REPRESSOR P66-BETA transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000017484.1|UniProtKB=W5NLT0 W5NLT0 PTHR15462:SF9 SERINE PROTEASE SERINE PROTEASE serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000011465.1|UniProtKB=W5N0D0 W5N0D0 PTHR11455:SF63 CRYPTOCHROME PHOTOLYASE_CRYPTOCHROME ALPHA_BETA DOMAIN-CONTAINING PROTEIN carbon-carbon lyase activity#GO:0016830;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;lyase activity#GO:0016829;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;deoxyribodipyrimidine photo-lyase activity#GO:0003904;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 response to radiation#GO:0009314;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;photoperiodism#GO:0009648;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to light stimulus#GO:0009416;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biological process#GO:0050789;circadian regulation of gene expression#GO:0032922;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;rhythmic process#GO:0048511;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;negative regulation of DNA-templated transcription#GO:0045892 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA photolyase#PC00014 LEPOC|Ensembl=ENSLOCG00000017434.1|UniProtKB=W5NLN0 W5NLN0 PTHR12002:SF225 CLAUDIN CLAUDIN transport#GO:0006810;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;paracellular transport#GO:0160184;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular process#GO:0009987;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000003118.1|UniProtKB=W5M5K9 W5M5K9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013767.1|UniProtKB=W5N8L8 W5N8L8 PTHR23412:SF19 STEREOCILIN RELATED STEREOCILIN cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000014179.1|UniProtKB=W5NA05 W5NA05 PTHR16655:SF2 COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT PROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000014130.1|UniProtKB=W5N9U6 W5N9U6 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;aminoglycan biosynthetic process#GO:0006023;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000008404.1|UniProtKB=W5MPA4 W5MPA4 PTHR10161:SF28 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 cation binding#GO:0043169;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;phosphoric ester hydrolase activity#GO:0042578;iron ion binding#GO:0005506;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;acid phosphatase activity#GO:0003993;ferrous iron binding#GO:0008198;catalytic activity#GO:0003824 bone remodeling#GO:0046849;homeostatic process#GO:0042592;tissue remodeling#GO:0048771;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;bone resorption#GO:0045453 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000009662.1|UniProtKB=W5MTU9 W5MTU9 PTHR24372:SF73 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE RICH REPEAT CONTAINING G PROTEIN-COUPLED RECEPTOR 6 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009150.1|UniProtKB=W5MRZ6 W5MRZ6 PTHR12233:SF4 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26A cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;cytosolic transport#GO:0016482;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;retromer complex#GO:0030904;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001525.1|UniProtKB=W5M030 W5M030 PTHR14948:SF19 NG5 TRANSMEMBRANE PROTEIN 233 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006175.1|UniProtKB=W5MGF0 W5MGF0 PTHR19879:SF7 TRANSCRIPTION INITIATION FACTOR TFIID PROTEASOMAL ATPASE-ASSOCIATED FACTOR 1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367 nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;nucleus#GO:0005634;proteasome complex#GO:0000502;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;peptidase complex#GO:1905368;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;SAGA complex#GO:0000124;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000018057.1|UniProtKB=W5NNE9 W5NNE9 PTHR15478:SF12 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 3 regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065 LEPOC|Ensembl=ENSLOCG00000016417.1|UniProtKB=W5NI21 W5NI21 PTHR13236:SF0 DYNEIN 2 LIGHT INTERMEDIATE CHAIN, ISOFORM 2 CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1 binding#GO:0005488;protein binding#GO:0005515 establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;intraciliary transport involved in cilium assembly#GO:0035735;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cilium assembly#GO:0060271;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641 microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;catalytic complex#GO:1902494;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000009263.1|UniProtKB=W5MSE4 W5MSE4 PTHR13038:SF14 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9B transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;cellular component organization#GO:0016043;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;reticulophagy#GO:0061709;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007075.1|UniProtKB=W5MJK4 W5MJK4 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER PANCREATIC ELASTASE catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005058.1|UniProtKB=W5MCI1 W5MCI1 PTHR10288:SF135 KH DOMAIN CONTAINING RNA BINDING PROTEIN K HOMOLOGY DOMAIN-CONTAINING PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003989.1|UniProtKB=W5M8R6 W5M8R6 PTHR10684:SF3 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 3 nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to hormone#GO:0009725;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 Gonadotropin-releasing hormone receptor pathway#P06664>Ncoa3#P06719 LEPOC|Ensembl=ENSLOCG00000013761.1|UniProtKB=W5N8M1 W5N8M1 PTHR11533:SF174 PROTEASE M1 ZINC METALLOPROTEASE PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824 peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;peptide catabolic process#GO:0043171;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000009209.1|UniProtKB=W5MS73 W5MS73 PTHR24388:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 367 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000013714.1|UniProtKB=W5N8F2 W5N8F2 PTHR23235:SF23 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000009188.1|UniProtKB=W5MS49 W5MS49 PTHR14580:SF0 MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 FAMILY MEMBER MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000000643.1|UniProtKB=W5LX53 W5LX53 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183-LIKE-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017509.1|UniProtKB=W5NLV5 W5NLV5 PTHR20889:SF2 PHOSPHATASE, ORPHAN 1, 2 PHOSPHOETHANOLAMINE_PHOSPHOCHOLINE PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 anatomical structure morphogenesis#GO:0009653;anatomical structure maturation#GO:0071695;ossification#GO:0001503;animal organ morphogenesis#GO:0009887;animal gross anatomical part developmental process#GO:0160108;biomineral tissue development#GO:0031214;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;system development#GO:0048731;skeletal system morphogenesis#GO:0048705;bone development#GO:0060348;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;tissue development#GO:0009888;bone mineralization#GO:0030282;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000248.1|UniProtKB=W5LVW7 W5LVW7 PTHR12411:SF1048 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN K cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016374.1|UniProtKB=W5NHV8 W5NHV8 PTHR13539:SF3 CALMODULIN-LYSINE N-METHYLTRANSFERASE CALMODULIN-LYSINE N-METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010352.1|UniProtKB=W5MWD2 W5MWD2 PTHR45760:SF5 FI19922P1-RELATED MITOCHONDRIAL GLUTATHIONE TRANSPORTER SLC25A40 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000015327.1|UniProtKB=W5NE00 W5NE00 PTHR10985:SF76 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 41 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 circadian regulation of gene expression#GO:0032922;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;rhythmic process#GO:0048511;negative regulation of DNA-templated transcription#GO:0045892;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000010882.1|UniProtKB=W5MY82 W5MY82 PTHR11384:SF59 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER LYSOSOMAL COBALAMIN TRANSPORTER ABCD4 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000010850.1|UniProtKB=W5MY41 W5MY41 PTHR11306:SF68 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 2 alcohol binding#GO:0043178;lipid binding#GO:0008289;cholesterol binding#GO:0015485;steroid binding#GO:0005496;binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934 cellular localization#GO:0051641;establishment of localization#GO:0051234;sterol transport#GO:0015918;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;intracellular transport#GO:0046907;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;intracellular sterol transport#GO:0032366;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cellular process#GO:0009987;cholesterol efflux#GO:0033344;establishment of localization in cell#GO:0051649 LEPOC|Ensembl=ENSLOCG00000006627.1|UniProtKB=W5MHZ4 W5MHZ4 PTHR23048:SF7 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 6 LIKE 2-RELATED ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;structural molecule activity#GO:0005198;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000010023.1|UniProtKB=W5MV44 W5MV44 PTHR22972:SF3 SERINE/THREONINE PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE PRAG1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012734.1|UniProtKB=W5N4Y2 W5N4Y2 PTHR45703:SF4 DYNEIN HEAVY CHAIN DYNEIN AXONEMAL HEAVY CHAIN 17 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000002293.1|UniProtKB=W5M2T5 W5M2T5 PTHR12995:SF2 FI21814P1 TRANSMEMBRANE PROTEIN 39B membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008710.1|UniProtKB=W5MQF1 W5MQF1 PTHR10943:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 cytoplasm#GO:0005737;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;endopeptidase complex#GO:1905369;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000017886.1|UniProtKB=W5NMY0 W5NMY0 PTHR24249:SF417 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 11 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016387.1|UniProtKB=W5NHX9 W5NHX9 PTHR45712:SF13 AGAP008170-PA KERATOCAN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009156.1|UniProtKB=W5MS22 W5MS22 PTHR15137:SF9 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 LEPOC|Ensembl=ENSLOCG00000014081.1|UniProtKB=W5N9R1 W5N9R1 PTHR13280:SF15 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 2 catabolic process#GO:0009056;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;localization within membrane#GO:0051668;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;protein localization to cell periphery#GO:1990778 LEPOC|Ensembl=ENSLOCG00000009119.1|UniProtKB=W5MRV9 W5MRV9 PTHR12002:SF24 CLAUDIN CLAUDIN-8 paracellular tight junction channel activity#GO:0160187;transporter activity#GO:0005215 paracellular transport#GO:0160184;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;cell-cell junction organization#GO:0045216;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043 bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000012375.1|UniProtKB=W5N3M9 W5N3M9 PTHR23170:SF3 NY-REN-58 ANTIGEN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 45 LEPOC|Ensembl=ENSLOCG00000000563.1|UniProtKB=W5LWW8 W5LWW8 PTHR46497:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008009.1|UniProtKB=W5MMX2 W5MMX2 PTHR10229:SF0 GTP-BINDING PROTEIN HFLX GTP-BINDING PROTEIN 6-RELATED binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000004250.1|UniProtKB=W5M9M5 W5M9M5 PTHR13233:SF0 MICROSPHERULE PROTEIN 1 MICROSPHERULE PROTEIN 1 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;NSL complex#GO:0044545;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017717.1|UniProtKB=W5NMG3 W5NMG3 PTHR24234:SF5 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G PROTEIN-COUPLED RECEPTOR 68 response to stimulus#GO:0050896;cellular response to abiotic stimulus#GO:0071214;cellular response to environmental stimulus#GO:0104004;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009535.1|UniProtKB=W5MTE5 W5MTE5 PTHR28604:SF2 FAMILY NOT NAMED RIKEN CDNA 2610028H24 GENE LEPOC|Ensembl=ENSLOCG00000017092.1|UniProtKB=W5NKG3 W5NKG3 PTHR24393:SF190 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 13 sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000004323.1|UniProtKB=W5M9V3 W5M9V3 PTHR43290:SF4 MEVALONATE KINASE MEVALONATE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 acyl-CoA metabolic process#GO:0006637;secondary alcohol biosynthetic process#GO:1902653;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;organophosphate metabolic process#GO:0019637;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407;acetyl-CoA metabolic process#GO:0006084;phospholipid metabolic process#GO:0006644;nucleoside phosphate metabolic process#GO:0006753;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;cholesterol biosynthetic process#GO:0006695;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;isoprenoid biosynthetic process#GO:0008299;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 carbohydrate kinase#PC00065 Cholesterol biosynthesis#P00014>Mevalonate kinase#P00492 LEPOC|Ensembl=ENSLOCG00000008729.1|UniProtKB=W5MQH0 W5MQH0 PTHR23253:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1 RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;translation factor activity#GO:0180051 metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000004740.1|UniProtKB=W5MBD5 W5MBD5 PTHR15430:SF2 GLOMULIN GLOMULIN enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;tube development#GO:0035295;vasculogenesis#GO:0001570;regulation of proteasomal protein catabolic process#GO:0061136;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;vasculature development#GO:0001944;regulation of catabolic process#GO:0009894;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;blood vessel morphogenesis#GO:0048514;system development#GO:0048731;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009839.1|UniProtKB=W5MUI3 W5MUI3 PTHR11506:SF27 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184 vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000009155.1|UniProtKB=W5MS01 W5MS01 PTHR11304:SF33 EPHRIN EPHRIN-A5 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of cytoskeleton organization#GO:0051493;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000017237.1|UniProtKB=W5NL10 W5NL10 PTHR11081:SF70 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE GEN HOMOLOG 1 DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;four-way junction DNA binding#GO:0000400;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;DNA binding#GO:0003677 replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;response to stimulus#GO:0050896;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 exodeoxyribonuclease#PC00098;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000013845.1|UniProtKB=W5N8Y9 W5N8Y9 PTHR24025:SF25 DESMOGLEIN FAMILY MEMBER CADHERIN-RELATED FAMILY MEMBER 1 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000010973.1|UniProtKB=W5MYT2 W5MYT2 PTHR45816:SF2 MIR DOMAIN-CONTAINING PROTEIN INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR Histamine H1 receptor mediated signaling pathway#P04385>IP3R#P04486;Metabotropic glutamate receptor group I pathway#P00041>IP3R#P01056;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IP3R#P00842;Endothelin signaling pathway#P00019>IP3 R#P00590;Alpha adrenergic receptor signaling pathway#P00002>IP3R#P00076;PDGF signaling pathway#P00047>IP3 receptor#P01160;Wnt signaling pathway#P00057>IP3 Gated Calcium Channel#P01426;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>IP3R#P01064 LEPOC|Ensembl=ENSLOCG00000001290.1|UniProtKB=W5LZA7 W5LZA7 A3GALT2 PTHR10462:SF33 GLYCOSYLTRANSFERASE-RELATED ALPHA 1,3-GALACTOSYLTRANSFERASE 2 glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000002912.1|UniProtKB=W5M4Z2 W5M4Z2 PTHR12185:SF15 SID1 TRANSMEMBRANE FAMILY MEMEBER SID1 TRANSMEMBRANE FAMILY MEMBER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nucleobase-containing compound transmembrane transporter activity#GO:0015932 macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;transport#GO:0006810;localization#GO:0051179;nucleic acid transport#GO:0050657;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;lysosome#GO:0005764;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000011366.1|UniProtKB=W5N028 W5N028 PTHR22775:SF51 SORTING NEXIN SORTING NEXIN-13 anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS-PX1#P00706 LEPOC|Ensembl=ENSLOCG00000001306.1|UniProtKB=W5LZC8 W5LZC8 PTHR11846:SF11 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;IMP metabolic process#GO:0046040;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 LEPOC|Ensembl=ENSLOCG00000007901.1|UniProtKB=W5MMI6 W5MMI6 PTHR46343:SF1 HYR DOMAIN-CONTAINING PROTEIN SUSHI REPEAT-CONTAINING PROTEIN SRPX organelle assembly#GO:0070925;localization#GO:0051179;vacuole organization#GO:0007033;cellular component organization#GO:0016043;endocytosis#GO:0006897;phagocytosis#GO:0006909;phagolysosome assembly#GO:0001845;lytic vacuole organization#GO:0080171;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;lysosome organization#GO:0007040;cellular component assembly#GO:0022607 LEPOC|Ensembl=ENSLOCG00000013317.1|UniProtKB=W5N702 W5N702 PTHR46966:SF1 HOMEOBOX EXPRESSED IN ES CELLS 1 HOMEOBOX EXPRESSED IN ES CELLS 1 sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;head development#GO:0060322;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;forebrain development#GO:0030900;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002631.1|UniProtKB=W5M408 W5M408 PTHR43213:SF5 BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462 LEPOC|Ensembl=ENSLOCG00000009974.1|UniProtKB=W5MUY4 W5MUY4 PTHR24390:SF205 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 49 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000005067.1|UniProtKB=W5MCJ2 W5MCJ2 PTHR10177:SF67 CYCLINS G1_S-SPECIFIC CYCLIN-D1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell cycle G1/S phase transition#GO:0044843;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;regulation of mitotic cell cycle phase transition#GO:1901990 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 CCKR signaling map#P06959>CCND1#G07280;CCKR signaling map#P06959>CCND1#G06986;Cell cycle#P00013>Cyclin D#P00484;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;PI3 kinase pathway#P00048>Cyclin d#G01546 LEPOC|Ensembl=ENSLOCG00000002281.1|UniProtKB=W5M2R5 W5M2R5 PTHR32379:SF2 GUANIDINOACETATE N-METHYLTRANSFERASE GUANIDINOACETATE N-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 monocarboxylic acid metabolic process#GO:0032787;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 methyltransferase#PC00155;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004902.1|UniProtKB=W5MBZ3 W5MBZ3 PTHR24027:SF450 CADHERIN-23 B-CADHERIN ISOFORM X1-RELATED binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;cell migration#GO:0016477;cell motility#GO:0048870 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;intracellular anatomical structure#GO:0005622 cell adhesion molecule#PC00069;cadherin#PC00057 Alzheimer disease-presenilin pathway#P00004>E-cadherin C-terminal fragment#P00117;Cadherin signaling pathway#P00012>Cadherin#P00471;Alzheimer disease-presenilin pathway#P00004>E-cadherin N-terminal fragment#P00165;Alzheimer disease-presenilin pathway#P00004>E-cadherin transmembrane fragment#P00139;Wnt signaling pathway#P00057>Cadherin#P01440;Alzheimer disease-presenilin pathway#P00004>E-cadherin#P00118;Alzheimer disease-presenilin pathway#P00004>E-cadherin intracellular fragment#P00168 LEPOC|Ensembl=ENSLOCG00000013097.1|UniProtKB=W5N675 W5N675 PTHR10632:SF2 SULFIDE:QUINONE OXIDOREDUCTASE SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002298.1|UniProtKB=W5M2S8 W5M2S8 PTHR17598:SF13 DNA POLYMERASE DELTA SUBUNIT 3 DNA POLYMERASE DELTA SUBUNIT 3 catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;DNA-directed DNA polymerase activity#GO:0003887 cellular response to abiotic stimulus#GO:0071214;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;response to UV#GO:0009411;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;DNA-templated DNA replication#GO:0006261;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA strand elongation involved in DNA replication#GO:0006271;cellular response to radiation#GO:0071478;cellular response to environmental stimulus#GO:0104004;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to abiotic stimulus#GO:0009628 protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;replisome#GO:0030894;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000009143.1|UniProtKB=W5MRY7 W5MRY7 PTHR45961:SF7 IP21249P DUAL SPECIFICITY PHOSPHATASE 28 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000002005.1|UniProtKB=W5M1R6 W5M1R6 PTHR23024:SF684 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE ISOFORM X1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 deacetylase#PC00087 LEPOC|Ensembl=ENSLOCG00000017727.1|UniProtKB=W5NMH2 W5NMH2 PTHR17503:SF0 SYNCOLLIN SYNCOLLIN LEPOC|Ensembl=ENSLOCG00000016930.1|UniProtKB=W5NJX2 W5NJX2 PTHR12748:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA replication origin binding#GO:0003688;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690 DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;pre-replicative complex#GO:0036387;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;DNA replication preinitiation complex#GO:0031261;chromosome#GO:0005694;organelle lumen#GO:0043233;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nuclear origin of replication recognition complex#GO:0005664;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear pre-replicative complex#GO:0005656 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000016032.1|UniProtKB=W5NGJ0 W5NGJ0 PTHR11937:SF37 ACTIN ACTIN-RELATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;structural molecule activity#GO:0005198;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036 Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Huntington disease#P00029>Actin#P00807 LEPOC|Ensembl=ENSLOCG00000003066.1|UniProtKB=W5M5H1 W5M5H1 PTHR43157:SF64 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED SI:DKEY-174N20.1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000002053.1|UniProtKB=W5M1Y7 W5M1Y7 PTHR12675:SF7 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000012902.1|UniProtKB=W5N5H6 W5N5H6 PTHR15021:SF1 DISCONNECTED-RELATED ZINC FINGER PROTEIN BASONUCLIN-1 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of transcription by RNA polymerase I#GO:0006356 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000002108.1|UniProtKB=W5M259 W5M259 PTHR11640:SF157 NEPHRIN V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008679.1|UniProtKB=W5MQA8 W5MQA8 PTHR45993:SF4 B-CELL LYMPHOMA/LEUKEMIA 11 B-CELL LYMPHOMA_LEUKEMIA 11B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002760.1|UniProtKB=W5M4E5 W5M4E5 PTHR13459:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1-RELATED catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 LEPOC|Ensembl=ENSLOCG00000006002.1|UniProtKB=W5MFU3 W5MFU3 PTHR18841:SF0 VITELLINE MEMBRANE OUTER LAYER PROTEIN I-RELATED VITELLINE MEMBRANE OUTER LAYER 1 HOMOLOG A-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013902.1|UniProtKB=W5N934 W5N934 PTHR45928:SF2 RE38146P SOLUTE CARRIER FAMILY 25 MEMBER 35 LEPOC|Ensembl=ENSLOCG00000011816.1|UniProtKB=W5N1M2 W5N1M2 PTHR23314:SF3 SPERM-ASSOCIATED ANTIGEN 6 ARMADILLO REPEAT-CONTAINING SPERM-ASSOCIATED ANTIGEN 6 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cilium movement#GO:0003341;cellular process#GO:0009987 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ciliary plasm#GO:0097014;sperm flagellum#GO:0036126;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;sperm principal piece#GO:0097228;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000006089.1|UniProtKB=W5MG75 W5MG75 PTHR46513:SF37 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LDL RECEPTOR RELATED PROTEIN 1-RELATED transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012321.1|UniProtKB=W5N3F4 W5N3F4 PTHR10829:SF1 CORTACTIN AND DREBRIN DREBRIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015 developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;cellular developmental process#GO:0048869;regulation of actin filament organization#GO:0110053;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament polymerization#GO:0030833;regulation of dendritic spine morphogenesis#GO:0061001;system development#GO:0048731;regulation of nervous system development#GO:0051960;regulation of supramolecular fiber organization#GO:1902903;positive regulation of neurogenesis#GO:0050769;postsynapse organization#GO:0099173;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;regulation of dendrite development#GO:0050773;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;regulation of actin cytoskeleton organization#GO:0032956;regulation of multicellular organismal process#GO:0051239;cytoskeleton organization#GO:0007010;regulation of synapse organization#GO:0050807;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;positive regulation of neuron projection development#GO:0010976;regulation of multicellular organismal development#GO:2000026;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;cell projection organization#GO:0030030;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of cell projection organization#GO:0031344;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;actin filament-based process#GO:0030029;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;regulation of dendrite morphogenesis#GO:0048814;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;positive regulation of cell differentiation#GO:0045597;neuron differentiation#GO:0030182;regulation of anatomical structure size#GO:0090066;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;organelle organization#GO:0006996;neuron projection development#GO:0031175;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;regulation of actin filament length#GO:0030832;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of biological quality#GO:0065008;regulation of postsynapse organization#GO:0099175;positive regulation of multicellular organismal process#GO:0051240;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;neuron projection#GO:0043005;cell junction#GO:0030054;synaptic membrane#GO:0097060;actin filament#GO:0005884;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000004349.1|UniProtKB=W5M9Y9 W5M9Y9 PTHR45810:SF17 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000018229.1|UniProtKB=W5NNX1 W5NNX1 PTHR23506:SF13 GH10249P VESICULAR ACETYLCHOLINE TRANSPORTER active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;regulation of biological process#GO:0050789;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;cell projection#GO:0042995;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;endocytic vesicle#GO:0030139;coated vesicle#GO:0030135;coated membrane#GO:0048475;presynapse#GO:0098793;neuron projection#GO:0043005;vesicle coat#GO:0030120;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;clathrin vesicle coat#GO:0030125;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated endocytic vesicle#GO:0045334;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;neuron projection terminus#GO:0044306;distal axon#GO:0150034;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;axon terminus#GO:0043679 secondary carrier transporter#PC00258;transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>VAChT#P01065;Nicotinic acetylcholine receptor signaling pathway#P00044>VAChT#P01089;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>VAChT#P01078 LEPOC|Ensembl=ENSLOCG00000011712.1|UniProtKB=W5N186 W5N186 PTHR46105:SF7 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7C RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000016427.1|UniProtKB=W5NI30 W5NI30 PTHR15881:SF2 MARGINAL ZONE B- AND B1-CELL-SPECIFIC PROTEIN MARGINAL ZONE B- AND B1-CELL-SPECIFIC PROTEIN regulation of immune effector process#GO:0002697;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000003966.1|UniProtKB=W5M8M8 W5M8M8 PTHR46051:SF11 SH2 DOMAIN-CONTAINING PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 1B regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000002998.1|UniProtKB=W5M582 W5M582 PTHR46730:SF3 POLYCYSTIN-1 POLYCYSTIN-1 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000015341.1|UniProtKB=W5NE17 W5NE17 PTHR15351:SF4 ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG ERLIN-2 protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;signaling#GO:0023052;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;SREBP signaling pathway#GO:0032933;response to chemical#GO:0042221 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000005912.1|UniProtKB=W5MFI2 W5MFI2 PTHR15263:SF1 I-KAPPA-B-LIKE PROTEIN IKBL NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000004073.1|UniProtKB=W5M906 W5M906 PTHR10927:SF1 RIBOSOME MATURATION PROTEIN SBDS RIBOSOME MATURATION PROTEIN SBDS RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015815.1|UniProtKB=W5NFR1 W5NFR1 PTHR11082:SF31 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(20A_20B) SYNTHASE [NAD(P)+]-LIKE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000001612.1|UniProtKB=W5M0F0 W5M0F0 PTHR14453:SF101 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14 ISOFORM X1 NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;transcription regulator activity#GO:0140110;glycosyltransferase activity#GO:0016757;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;transferase activity#GO:0016740;transcription corepressor activity#GO:0003714 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biological process#GO:0050789;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biological process#GO:0048519;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of gene expression#GO:0010629;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000003974.1|UniProtKB=W5M8N5 W5M8N5 PTHR45925:SF3 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 516 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000016684.1|UniProtKB=W5NJ03 W5NJ03 PTHR11416:SF7 PRO-OPIOMELANOCORTIN PRO-OPIOMELANOCORTIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell communication#GO:0007154;pigmentation#GO:0043473;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;cellular pigmentation#GO:0033059;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Cortocotropin releasing factor receptor signaling pathway#P04380>ACTH#P04453;Opioid proopiomelanocortin pathway#P05917>ACTH#P06008;Cortocotropin releasing factor receptor signaling pathway#P04380>proopiomelanocortin#G04671;Cortocotropin releasing factor receptor signaling pathway#P04380>beta-endorphin#P04455;Opioid proopiomelanocortin pathway#P05917>alpha-MSH#P06007;Opioid proopiomelanocortin pathway#P05917>beta-Endorphin#P06006;Opioid proopiomelanocortin pathway#P05917>proopiomelanocortin#P06010;Cortocotropin releasing factor receptor signaling pathway#P04380>proopiomelanocortin#P04452 LEPOC|Ensembl=ENSLOCG00000008132.1|UniProtKB=W5MNC7 W5MNC7 PTHR11730:SF42 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE B passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;homeostatic process#GO:0042592 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014653.1|UniProtKB=W5NBM4 W5NBM4 PTHR11132:SF255 SOLUTE CARRIER FAMILY 35 GDP-FUCOSE TRANSPORTER 1 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleotide-sugar transmembrane transport#GO:0015780;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004889.1|UniProtKB=W5MBW8 W5MBW8 PTHR15069:SF1 PROTEASOME ASSEMBLY CHAPERONE 1 PROTEASOME ASSEMBLY CHAPERONE 1 protein-containing complex binding#GO:0044877;binding#GO:0005488 chaperone-mediated protein complex assembly#GO:0051131;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;protein folding chaperone complex#GO:0101031;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012249.1|UniProtKB=W5N363 W5N363 PTHR10910:SF17 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN INACTIVE DOUBLE-STRANDED RNA-SPECIFIC EDITASE B2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;RNA binding#GO:0003723;adenosine deaminase activity#GO:0004000;catalytic activity, acting on a tRNA#GO:0140101;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;tRNA-specific adenosine deaminase activity#GO:0008251 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;base conversion or substitution editing#GO:0016553;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;adenosine to inosine editing#GO:0006382;RNA biosynthetic process#GO:0032774 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009485.1|UniProtKB=W5MT81 W5MT81 PTHR13038:SF13 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9A intramembrane lipid carrier activity#GO:0140303;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128 organelle assembly#GO:0070925;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization#GO:0016043;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;reticulophagy#GO:0061709;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component assembly#GO:0022607;macroautophagy#GO:0016236 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008725.1|UniProtKB=W5MQG2 W5MQG2 PTHR10217:SF506 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED INWARDLY RECTIFYING POTASSIUM CHANNEL KCNH2 ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843 potassium ion transport#GO:0006813;biological regulation#GO:0065007;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000015988.1|UniProtKB=W5NGC5 W5NGC5 PTHR15712:SF23 ARMADILLO REPEAT CONTAINING PROTEIN ARMADILLO REPEAT CONTAINING 10 establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;axonal transport#GO:0098930;organelle localization#GO:0051640;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;axo-dendritic transport#GO:0008088;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;intracellular transport#GO:0046907 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004411.1|UniProtKB=W5MA60 W5MA60 PTHR11969:SF99 MAX DIMERIZATION, MAD MAX-BINDING PROTEIN MNT DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000009911.1|UniProtKB=W5MUQ7 W5MUQ7 PTHR11523:SF11 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 metal ion transport#GO:0030001;homeostatic process#GO:0042592;export from cell#GO:0140352;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;potassium ion homeostasis#GO:0055075;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 cation-transporting ATPase complex#GO:0090533;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009972.1|UniProtKB=W5MUZ9 W5MUZ9 PTHR24040:SF0 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN VITAMIN K-DEPENDENT PROTEIN S regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;negative regulation of coagulation#GO:0050819;regulation of coagulation#GO:0050818 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Blood coagulation#P00011>PS#P00412 LEPOC|Ensembl=ENSLOCG00000002732.1|UniProtKB=W5M4A8 W5M4A8 PTHR24037:SF13 HEART DEVELOPMENT PROTEIN WITH EGF-LIKE DOMAINS 1 PROTEIN HEG LEPOC|Ensembl=ENSLOCG00000006489.1|UniProtKB=W5MHI0 W5MHI0 PTHR15494:SF0 CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000007028.1|UniProtKB=W5MJF0 W5MJF0 PTHR45664:SF7 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008122.1|UniProtKB=W5MNA6 W5MNA6 PTHR45991:SF1 PACHYTENE CHECKPOINT PROTEIN 2 PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;regulation of reproductive process#GO:2000241;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of organelle organization#GO:0010639;primary metabolic process#GO:0044238;negative regulation of cellular component organization#GO:0051129;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;homologous recombination#GO:0035825 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008873.1|UniProtKB=W5MQZ5 W5MQZ5 PTHR11471:SF34 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003257.1|UniProtKB=W5M641 W5M641 PTHR15726:SF6 RAB11-FAMILY INTERACTING PROTEIN RAB11 FAMILY-INTERACTING PROTEIN 3 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;endocytic recycling#GO:0032456;regulation of cell cycle#GO:0051726;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179 cytoplasm#GO:0005737;plasma membrane#GO:0005886;cell division site#GO:0032153;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;cleavage furrow#GO:0032154;recycling endosome#GO:0055037;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;midbody#GO:0030496;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000002531.1|UniProtKB=W5M3M0 W5M3M0 PTHR46698:SF4 CROSSVEINLESS 2 VWFD DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001554.1|UniProtKB=W5M084 W5M084 PTHR14131:SF7 ANOSMIN ANOSMIN-1B ISOFORM X1 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;cellular process#GO:0009987;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000008609.1|UniProtKB=W5MQ11 W5MQ11 PTHR15128:SF0 TAL1 SCL INTERRUPTING LOCUS SCL-INTERRUPTING LOCUS PROTEIN cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cytoskeleton organization#GO:0007010;protein localization to microtubule organizing center#GO:1905508;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;mitotic spindle organization#GO:0007052;response to stimulus#GO:0050896;signaling#GO:0023052;spindle organization#GO:0007051;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;macromolecule localization#GO:0033036;protein localization to microtubule cytoskeleton#GO:0072698;biological regulation#GO:0065007;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;protein localization to centrosome#GO:0071539;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;mitotic cell cycle#GO:0000278 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003781.1|UniProtKB=W5M810 W5M810 PTHR24089:SF671 SOLUTE CARRIER FAMILY 25 DKFZP586G0123-LIKE transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;localization#GO:0051179;organophosphate ester transport#GO:0015748 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 LEPOC|Ensembl=ENSLOCG00000014974.1|UniProtKB=W5NCT1 W5NCT1 PTHR16059:SF11 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000003952.1|UniProtKB=W5M8L0 W5M8L0 ELOVL1 PTHR11157:SF19 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000014846.1|UniProtKB=W5NCC2 W5NCC2 PTHR21347:SF14 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1-RELATED cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010090.1|UniProtKB=W5MVD5 W5MVD5 PTHR31247:SF7 TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER TRANSMEMBRANE PROTEIN 198 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000001574.1|UniProtKB=W5M0B6 W5M0B6 PTHR42861:SF2 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 1 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000012438.1|UniProtKB=W5N3V1 W5N3V1 PTHR23147:SF237 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 5 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016975.1|UniProtKB=W5NK28 W5NK28 PTHR14166:SF15 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;regulation of locomotion#GO:0040012;nervous system development#GO:0007399;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of cell migration#GO:0030334;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of biological quality#GO:0065008;regulation of cell motility#GO:2000145;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174;Axon guidance mediated by Slit/Robo#P00008>SrGAP#P00350 LEPOC|Ensembl=ENSLOCG00000005391.1|UniProtKB=W5MDN7 W5MDN7 PTHR46484:SF1 SI:CH211-171H4.5-RELATED B-CELL RECEPTOR CD22-RELATED LEPOC|Ensembl=ENSLOCG00000011686.1|UniProtKB=W5N165 W5N165 PTHR11590:SF42 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE COAGULATION FACTOR XIII A CHAIN catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 gene expression#GO:0010467;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to stress#GO:0006950;response to wounding#GO:0009611;coagulation#GO:0050817;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;blood coagulation#GO:0007596;metabolic process#GO:0008152;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;primary metabolic process#GO:0044238;hemostasis#GO:0007599;protein activation cascade#GO:0072376;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;wound healing#GO:0042060;blood coagulation, fibrin clot formation#GO:0072378 transferase#PC00220 Blood coagulation#P00011>FXIIIa#P00419;Blood coagulation#P00011>FXIII#P00453 LEPOC|Ensembl=ENSLOCG00000014961.1|UniProtKB=W5NCR0 W5NCR0 PTHR24248:SF3 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-3 ADRENERGIC RECEPTOR G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;hormone binding#GO:0042562;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;vasodilation#GO:0042311;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;biological regulation#GO:0065007;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of anatomical structure size#GO:0090066;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Beta3 adrenergic receptor signaling pathway#P04379>Beta3#P04449 LEPOC|Ensembl=ENSLOCG00000009239.1|UniProtKB=W5MSB6 W5MSB6 PTHR11453:SF15 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN 3 chloride transmembrane transporter activity#GO:0015108;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804 regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000017719.1|UniProtKB=W5NMG5 W5NMG5 PTHR23268:SF28 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 27 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013759.1|UniProtKB=W5N8L3 W5N8L3 PTHR18945:SF477 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT BETA ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023 metal ion transport#GO:0030001;membrane depolarization#GO:0051899;striated muscle contraction#GO:0006941;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;response to nitrogen compound#GO:1901698;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;neuromuscular process#GO:0050905;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;multicellular organismal process#GO:0032501;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;system process#GO:0003008;establishment of localization#GO:0051234;muscle contraction#GO:0006936;transport#GO:0006810;signaling#GO:0023052;skeletal muscle contraction#GO:0003009;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;muscle system process#GO:0003012;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;nervous system process#GO:0050877;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391 postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cell junction#GO:0030054;transporter complex#GO:1990351;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095 LEPOC|Ensembl=ENSLOCG00000014101.1|UniProtKB=W5N9R5 W5N9R5 PTHR15871:SF2 PH DOMAIN-CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY O MEMBER 2 cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;programmed cell death#GO:0012501 LEPOC|Ensembl=ENSLOCG00000017373.1|UniProtKB=W5NLG9 W5NLG9 PTHR24233:SF11 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 34-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001556.1|UniProtKB=W5M073 W5M073 PTHR44991:SF2 IMMUNOGLOBULIN SUPERFAMILY MEMBER 5 IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000011305.1|UniProtKB=W5MZT0 W5MZT0 PTHR23055:SF11 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 2 calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;molecular function activator activity#GO:0140677;cation binding#GO:0043169;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;cyclase regulator activity#GO:0010851;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772 visual perception#GO:0007601;multicellular organismal process#GO:0032501;system process#GO:0003008;sensory perception of light stimulus#GO:0050953;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929;photoreceptor inner segment#GO:0001917;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000009439.1|UniProtKB=W5MT11 W5MT11 PTHR10558:SF2 SOMATOSTATIN SOMATOSTATIN hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000011587.1|UniProtKB=W5N0S8 W5N0S8 PTHR15592:SF41 MATRIN 3/NUCLEAR PROTEIN 220-RELATED MATRIN-3-LIKE binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000003216.1|UniProtKB=W5M6J0 W5M6J0 PTHR23317:SF77 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 9 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of small GTPase mediated signal transduction#GO:0051056 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000002650.1|UniProtKB=W5M406 W5M406 PTHR46252:SF1 BRORIN FAMILY MEMBER ZGC:113531 negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of response to stimulus#GO:0048585;regulation of BMP signaling pathway#GO:0030510;negative regulation of BMP signaling pathway#GO:0030514;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 LEPOC|Ensembl=ENSLOCG00000005406.1|UniProtKB=W5MDR1 W5MDR1 PTHR12315:SF1 BICOID-INTERACTING PROTEIN RELATED RNA 5'-MONOPHOSPHATE METHYLTRANSFERASE RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168 positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000002389.1|UniProtKB=W5M347 W5M347 PTHR11046:SF0 OLIGORIBONUCLEASE, MITOCHONDRIAL OLIGORIBONUCLEASE, MITOCHONDRIAL exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006021.1|UniProtKB=W5MFW2 W5MFW2 PTHR32422:SF0 ADHERENS JUNCTION-ASSOCIATED PROTEIN 1 ADHERENS JUNCTION-ASSOCIATED PROTEIN 1 beta-catenin binding#GO:0008013;protein binding#GO:0005515;binding#GO:0005488 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;cell-cell contact zone#GO:0044291;anchoring junction#GO:0070161;adherens junction#GO:0005912;side of membrane#GO:0098552;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000007248.1|UniProtKB=W5MK61 W5MK61 PTHR15431:SF19 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 20 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centrosome#GO:0005813;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002330.1|UniProtKB=W5M2Y7 W5M2Y7 PTHR47765:SF2 3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN EXONUCLEASE MUT-7 HOMOLOG LEPOC|Ensembl=ENSLOCG00000006846.1|UniProtKB=W5MIT5 W5MIT5 PTHR24082:SF210 NUCLEAR HORMONE RECEPTOR THYROID HORMONE RECEPTOR BETA molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to chemical stimulus#GO:0070887;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000011425.1|UniProtKB=W5N097 W5N097 PTHR22692:SF16 MYOSIN VII, XV UNCONVENTIONAL MYOSIN-XVB actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000011100.1|UniProtKB=W5MZ25 W5MZ25 PTHR46139:SF1 ALKALINE CERAMIDASE ALKALINE CERAMIDASE 2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;alcohol biosynthetic process#GO:0046165;lipid catabolic process#GO:0016042;cellular process#GO:0009987;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 LEPOC|Ensembl=ENSLOCG00000016901.1|UniProtKB=W5NJT2 W5NJT2 PTHR10926:SF17 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;biological regulation#GO:0065007;phospholipid transport#GO:0015914;membrane organization#GO:0061024;phospholipid translocation#GO:0045332 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000001682.1|UniProtKB=W5M0P3 W5M0P3 PTHR15600:SF44 SACSIN SACSIN binding#GO:0005488;protein-folding chaperone binding#GO:0051087;heat shock protein binding#GO:0031072;protein binding#GO:0005515;Hsp70 protein binding#GO:0030544 LEPOC|Ensembl=ENSLOCG00000016334.1|UniProtKB=W5NHQ9 W5NHQ9 PTHR11616:SF101 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT2 secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370 sodium ion transport#GO:0006814;L-leucine transport#GO:0015820;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;amino acid transport#GO:0006865;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;branched-chain amino acid transport#GO:0015803;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 LEPOC|Ensembl=ENSLOCG00000003632.1|UniProtKB=W5M7E9 W5M7E9 PTHR12460:SF2 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 1A protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899 metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000004885.1|UniProtKB=W5MBX1 W5MBX1 PTHR23252:SF29 INTIMAL THICKNESS RECEPTOR-RELATED INTEGRAL MEMBRANE PROTEIN GPR180 LEPOC|Ensembl=ENSLOCG00000008022.1|UniProtKB=W5MMY7 W5MMY7 PTHR28494:SF1 UPF0600 PROTEIN C5ORF51 RAB7A-INTERACTING MON1-CCZ1 COMPLEX SUBUNIT 1 LEPOC|Ensembl=ENSLOCG00000002791.1|UniProtKB=W5M4H4 W5M4H4 PTHR19282:SF504 TETRASPANIN TETRASPANIN-18B-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010461.1|UniProtKB=W5MWR0 W5MWR0 PTHR15907:SF122 DUF614 FAMILY PROTEIN-RELATED PLAC8-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000016014.1|UniProtKB=W5NGG5 W5NGG5 PTHR31952:SF1 CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1 CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000005181.1|UniProtKB=W5MCX7 W5MCX7 PTHR11615:SF322 NITRATE, FORMATE, IRON DEHYDROGENASE CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 3 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000003026.1|UniProtKB=W5M5A8 W5M5A8 PTHR10704:SF74 CARBOHYDRATE SULFOTRANSFERASE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;amino sugar metabolic process#GO:0006040 trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000000262.1|UniProtKB=W5LVZ7 W5LVZ7 PTHR33769:SF1 TESTIS-EXPRESSED PROTEIN 26 ISOFORM X3 TESTIS-EXPRESSED PROTEIN 26 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012347.1|UniProtKB=W5N3J1 W5N3J1 PTHR10218:SF68 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-2 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception of taste#GO:0050912;nervous system process#GO:0050877;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;detection of chemical stimulus#GO:0009593;sensory perception of bitter taste#GO:0050913;detection of chemical stimulus involved in sensory perception of bitter taste#GO:0001580;system process#GO:0003008;sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;signal transduction#GO:0007165;cellular process#GO:0009987 side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;photoreceptor inner segment#GO:0001917;catalytic complex#GO:1902494;cilium#GO:0005929;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733 heterotrimeric G-protein#PC00117;G-protein#PC00020 Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;PI3 kinase pathway#P00048>Galpha#P01199 LEPOC|Ensembl=ENSLOCG00000017893.1|UniProtKB=W5NMY7 W5NMY7 PTHR11849:SF276 ETS TRANSCRIPTION FACTOR SPI-C DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011676.1|UniProtKB=W5N145 W5N145 PTHR24092:SF84 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VD intramembrane lipid carrier activity#GO:0140303;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;macromolecule localization#GO:0033036;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003265.1|UniProtKB=W5M645 W5M645 PTHR32289:SF2 PROTEIN FAM167A ALANINE- AND ARGININE-RICH DOMAIN-CONTAINING PROTEIN response to oxygen-containing compound#GO:1901700;response to lipid#GO:0033993;response to chemical#GO:0042221;response to stimulus#GO:0050896 LEPOC|Ensembl=ENSLOCG00000007208.1|UniProtKB=W5MK13 W5MK13 PTHR11486:SF23 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 5 protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;fibroblast growth factor receptor binding#GO:0005104;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851 nervous system development#GO:0007399;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000007707.1|UniProtKB=W5MLU4 W5MLU4 PTHR15487:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000003311.1|UniProtKB=W5M6B8 W5M6B8 PTHR11049:SF1 ACYL COENZYME A THIOESTER HYDROLASE ACYL-COENZYME A THIOESTERASE 11 hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617;deacylase activity#GO:0160215;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000002659.1|UniProtKB=W5M432 W5M432 PTHR24031:SF706 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX27-RELATED RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005075.1|UniProtKB=W5MCK2 W5MCK2 PTHR22776:SF29 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4 immune system process#GO:0002376;immune response#GO:0006955;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000719.1|UniProtKB=W5LXH3 W5LXH3 PTHR23403:SF1 TREHALASE TREHALASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056 LEPOC|Ensembl=ENSLOCG00000008012.1|UniProtKB=W5MMX1 W5MMX1 PTHR12892:SF11 FGF RECEPTOR ACTIVATING PROTEIN 1 ACYLTRANSFERASE PGAP2 lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003645.1|UniProtKB=W5M7J2 W5M7J2 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010907.1|UniProtKB=W5MYC3 W5MYC3 PTHR11274:SF0 RAD25/XP-B DNA REPAIR HELICASE GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE_TRANSLOCASE SUBUNIT XPB ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097 transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 transferase complex#GO:1990234;nucleotide-excision repair complex#GO:0000109;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transcription factor TFIIH holo complex#GO:0005675;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000013939.1|UniProtKB=W5N975 W5N975 PTHR44305:SF2 SI:DKEY-192D15.2-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000005987.1|UniProtKB=W5MFT4 W5MFT4 PTHR24099:SF7 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED CARDIOMYOPATHY-ASSOCIATED PROTEIN 5 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004481.1|UniProtKB=W5MAE4 W5MAE4 PTHR10985:SF27 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HES FAMILY BHLH TRANSCRIPTION FACTOR 6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;pattern specification process#GO:0007389;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000016537.1|UniProtKB=W5NIH0 W5NIH0 PTHR24416:SF257 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE MER transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 cell motility#GO:0048870;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell migration#GO:0016477;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;establishment of localization#GO:0051234;import into cell#GO:0098657;multicellular organism development#GO:0007275;phagocytosis#GO:0006909;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;developmental process#GO:0032502 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009382.1|UniProtKB=W5MST8 W5MST8 PTHR11829:SF195 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000004772.1|UniProtKB=W5MBG6 W5MBG6 PTHR43053:SF8 GLYCOSIDASE FAMILY 31 ALPHA-GALACTOSIDASE MYORG striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;cellular developmental process#GO:0048869;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;tissue development#GO:0009888;cellular process#GO:0009987;skeletal muscle tissue development#GO:0007519;muscle tissue development#GO:0060537;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;glucosidase#PC00108 LEPOC|Ensembl=ENSLOCG00000013043.1|UniProtKB=W5N611 W5N611 PTHR24064:SF192 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 23 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014929.1|UniProtKB=W5NCM4 W5NCM4 PTHR10264:SF130 BAND 7 PROTEIN-RELATED STOMATIN-LIKE PROTEIN 1 transporter regulator activity#GO:0141108;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000002371.1|UniProtKB=W5M319 W5M319 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN LOW QUALITY PROTEIN: ODORANT RECEPTOR 125-6-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007682.1|UniProtKB=W5MLR9 W5MLR9 PTHR24070:SF428 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RHEB kinase activator activity#GO:0019209;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;hydrolase activity, acting on acid anhydrides#GO:0016817;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of TORC1 signaling#GO:1903432;positive regulation of TORC1 signaling#GO:1904263;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of response to stimulus#GO:0048584;intracellular signaling cassette#GO:0141124;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of TOR signaling#GO:0032008;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000010025.1|UniProtKB=W5MV64 W5MV64 PTHR11808:SF15 TRANS-SULFURATION ENZYME FAMILY MEMBER CYSTATHIONINE GAMMA-LYASE catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 lyase#PC00144;metabolite interconversion enzyme#PC00262 Methionine biosynthesis#P02753>O-Succinyl homoserine lyase#P03026 LEPOC|Ensembl=ENSLOCG00000007051.1|UniProtKB=W5MJH4 W5MJH4 PTHR24324:SF5 HOMEOBOX PROTEIN HHEX HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000009938.1|UniProtKB=W5MUU8 W5MUU8 PTHR10137:SF5 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C 1 monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000011980.1|UniProtKB=W5N271 W5N271 PTHR41693:SF1 HEME-BINDING PROTEIN 1 SI:CH211-243A20.3 LEPOC|Ensembl=ENSLOCG00000015808.1|UniProtKB=W5NFQ5 W5NFQ5 PTHR11814:SF33 SULFATE TRANSPORTER PENDRIN carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;chloride transport#GO:0006821 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009673.1|UniProtKB=W5MTV9 W5MTV9 PTHR46791:SF13 EXPRESSED PROTEIN INTEGRASE CORE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000001802.1|UniProtKB=W5M1F1 W5M1F1 PTHR14017:SF9 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 6A catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;chromatin DNA binding#GO:0031490;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;sequence-specific double-stranded DNA binding#GO:1990837;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;histone demethylase activity#GO:0032452;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;histone modifying activity#GO:0140993 developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;heart development#GO:0007507;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009092.1|UniProtKB=W5MRS7 W5MRS7 PTHR35450:SF2 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN C1Q DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012165.1|UniProtKB=W5N2V1 W5N2V1 PTHR22811:SF37 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 9 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization#GO:0016043;Golgi organization#GO:0007030 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783 membrane traffic protein#PC00150;vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000012182.1|UniProtKB=W5N2X0 W5N2X0 PTHR11814:SF16 SULFATE TRANSPORTER SULFATE TRANSPORTER monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;carboxylic acid transmembrane transporter activity#GO:0046943 localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013013.1|UniProtKB=W5N5X3 W5N5X3 PTHR10353:SF68 GLYCOSYL HYDROLASE BETA-KLOTHO catalytic activity#GO:0003824;beta-glucosidase activity#GO:0008422;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosidase#PC00110;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012703.1|UniProtKB=W5N4R8 W5N4R8 PTHR16520:SF3 KINETOCHORE SCAFFOLD 1 OUTER KINETOCHORE KNL1 COMPLEX SUBUNIT KNL1 localization#GO:0051179;intracellular protein localization#GO:0008104;metaphase chromosome alignment#GO:0051310;organelle localization#GO:0051640;chromosome segregation#GO:0007059;protein localization to organelle#GO:0033365;chromosome localization#GO:0050000;macromolecule localization#GO:0033036;cell cycle#GO:0007049;attachment of spindle microtubules to kinetochore#GO:0008608;protein localization to kinetochore#GO:0034501;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013312.1|UniProtKB=W5N6Z5 W5N6Z5 PTHR24327:SF28 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development ending in birth or egg hatching#GO:0009792;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000005321.1|UniProtKB=W5MDF6 W5MDF6 PTHR46117:SF2 FI24210P1 UPSTREAM STIMULATORY FACTOR 2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 PDGF signaling pathway#P00047>c-fos#P01145 LEPOC|Ensembl=ENSLOCG00000003081.1|UniProtKB=W5M5G9 W5M5G9 PTHR46061:SF2 THYROTROPIN-RELEASING HORMONE RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH Receptor#P04580 LEPOC|Ensembl=ENSLOCG00000004149.1|UniProtKB=W5M9A3 W5M9A3 PTHR24406:SF42 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED FI01110P-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014467.1|UniProtKB=W5NB02 W5NB02 PTHR22748:SF4 AP ENDONUCLEASE DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 2 hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;exonuclease activity#GO:0004527;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;DNA exonuclease activity#GO:0004529;3'-5' exonuclease activity#GO:0008408;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081 response to stress#GO:0006950;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018067.1|UniProtKB=W5NNF9 W5NNF9 PTHR11537:SF44 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 10 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;action potential#GO:0001508;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000003843.1|UniProtKB=W5M877 W5M877 PTHR13282:SF6 PROTEIN FAM32A PROTEIN FAM32A nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000003889.1|UniProtKB=W5M8D2 W5M8D2 PTHR46271:SF2 HOMEOBOX PROTEIN, PUTATIVE-RELATED RETINA AND ANTERIOR NEURAL FOLD HOMEOBOX PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013034.1|UniProtKB=W5N5Z7 W5N5Z7 PTHR11588:SF514 TUBULIN TUBULIN BETA CHAIN ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874 tubulin#PC00228;cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 LEPOC|Ensembl=ENSLOCG00000007896.1|UniProtKB=W5MMI2 W5MMI2 PTHR23189:SF48 RNA RECOGNITION MOTIF-CONTAINING MSX2-INTERACTING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of DNA-templated transcription#GO:0006355;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA splicing#GO:0043484;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018160.1|UniProtKB=W5NNQ2 W5NNQ2 PTHR23212:SF0 BRAIN ACID SOLUBLE PROTEIN 1 BRAIN ACID SOLUBLE PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000013153.1|UniProtKB=W5N6E8 W5N6E8 PTHR13493:SF3 ZINC FINGER CCHC DOMAIN-CONTAINING RRNA N(6)-ADENOSINE-METHYLTRANSFERASE ZCCHC4 transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;methylation#GO:0032259;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000007629.1|UniProtKB=W5MLJ5 W5MLJ5 PTHR46032:SF4 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 2 glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015958.1|UniProtKB=W5NG98 W5NG98 PTHR24044:SF448 NOTCH LIGAND FAMILY MEMBER PROTEIN JAGGED-1 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Serrate#P01104;Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Next#P01103 LEPOC|Ensembl=ENSLOCG00000011140.1|UniProtKB=W5MZ80 W5MZ80 PTHR18966:SF361 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2C dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;synaptic signaling#GO:0099536;regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;nervous system process#GO:0050877;positive regulation of synaptic transmission#GO:0050806;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;system process#GO:0003008;regulation of synaptic plasticity#GO:0048167;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;chemical synaptic transmission, postsynaptic#GO:0099565;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of postsynaptic membrane potential#GO:0060078;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;transporter complex#GO:1990351;cell junction#GO:0030054;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NR2C#P01006;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039 LEPOC|Ensembl=ENSLOCG00000017913.1|UniProtKB=W5NN07 W5NN07 PTHR16083:SF8 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 10 protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular process#GO:0009987;heart development#GO:0007507;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cardiac muscle cell differentiation#GO:0055007;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;animal organ development#GO:0048513;striated muscle cell differentiation#GO:0051146;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;cell differentiation#GO:0030154;circulatory system development#GO:0072359;muscle structure development#GO:0061061;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;system development#GO:0048731 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016842.1|UniProtKB=W5NJK7 W5NJK7 PTHR22883:SF28 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC14 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010596.1|UniProtKB=W5MX68 W5MX68 PTHR31457:SF2 METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE C PROTEIN CYANOCOBALAMIN REDUCTASE _ ALKYLCOBALAMIN DEALKYLASE flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on metal ions#GO:0016722;nucleotide binding#GO:0000166;catalytic activity#GO:0003824 metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000003731.1|UniProtKB=W5M7S7 W5M7S7 PTHR15319:SF1 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT C TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT C sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription by RNA polymerase I#P00022>TAF-IC#P00649;General transcription regulation#P00023>TBP-associated factors#P00658 LEPOC|Ensembl=ENSLOCG00000001642.1|UniProtKB=W5M0I3 W5M0I3 PTHR12644:SF1 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytoskeleton organization#GO:0007010;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;actin nucleation#GO:0045010;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 cell periphery#GO:0071944;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 LEPOC|Ensembl=ENSLOCG00000015652.1|UniProtKB=W5NF57 W5NF57 PTHR10159:SF109 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;formation of primary germ layer#GO:0001704;response to stimulus#GO:0050896;signaling#GO:0023052;gastrulation#GO:0007369;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;endoderm development#GO:0007492;regulation of MAPK cascade#GO:0043408;embryo development#GO:0009790;negative regulation of signal transduction#GO:0009968;endoderm formation#GO:0001706;cellular process#GO:0009987;signal transduction#GO:0007165 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000017696.1|UniProtKB=W5NME2 W5NME2 PTHR24228:SF77 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR B2 BRADYKININ RECEPTOR G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017861.1|UniProtKB=W5NMV5 W5NMV5 PTHR23430:SF410 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;heterochromatin organization#GO:0070828;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016461.1|UniProtKB=W5NI76 W5NI76 PTHR11537:SF91 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNG3 transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;action potential#GO:0001508;metal ion transport#GO:0030001 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000002715.1|UniProtKB=W5M4B2 W5M4B2 PTHR45807:SF3 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK3 non-membrane spanning protein tyrosine kinase activity#GO:0004715;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;hormone receptor binding#GO:0051427;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;response to stress#GO:0006950;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;response to type II interferon#GO:0034341;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;interleukin-15-mediated signaling pathway#GO:0035723;interleukin-9-mediated signaling pathway#GO:0038113;cell surface receptor signaling pathway via STAT#GO:0097696;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;interleukin-7-mediated signaling pathway#GO:0038111;interleukin-2-mediated signaling pathway#GO:0038110;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to peptide hormone stimulus#GO:0071375;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;immune response#GO:0006955;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to other organism#GO:0051707;developmental process#GO:0032502;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;innate immune response#GO:0045087;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;defense response#GO:0006952 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor tyrosine protein kinase#PC00168 Interleukin signaling pathway#P00036>Jak#P00978;JAK/STAT signaling pathway#P00038>Jak#P01034;PDGF signaling pathway#P00047>Jak#P01155 LEPOC|Ensembl=ENSLOCG00000000609.1|UniProtKB=W5LX24 W5LX24 PTHR14928:SF13 MICRO-RNA BINDING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7A binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012501.1|UniProtKB=W5N431 W5N431 PTHR10513:SF48 DEOXYNUCLEOSIDE KINASE DEOXYCYTIDINE KINASE 2 transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;deoxynucleoside kinase activity#GO:0019136 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007819.1|UniProtKB=W5MM82 W5MM82 PTHR24183:SF1 FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1 FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012878.1|UniProtKB=W5N5H5 W5N5H5 PTHR19229:SF280 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP BINDING CASSETTE SUBFAMILY A MEMBER 8-RELATED molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810;establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000016431.1|UniProtKB=W5NI36 W5NI36 PTHR24331:SF4 DBX HOMEOBOX PROTEIN DBX2 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 LEPOC|Ensembl=ENSLOCG00000008508.1|UniProtKB=W5MPP4 W5MPP4 PTHR11132:SF515 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER D3 active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006708.1|UniProtKB=W5MI89 W5MI89 PTHR11537:SF87 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL KCNC1 transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;action potential#GO:0001508;metal ion transport#GO:0030001 plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;membrane#GO:0016020;cell periphery#GO:0071944;axon terminus#GO:0043679;neuron projection membrane#GO:0032589;voltage-gated potassium channel complex#GO:0008076;neuron projection terminus#GO:0044306;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;protein-containing complex#GO:0032991;cell leading edge#GO:0031252;presynapse#GO:0098793;neuron projection#GO:0043005;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;synaptic membrane#GO:0097060;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;postsynapse#GO:0098794;cell body#GO:0044297;cell projection membrane#GO:0031253;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000005138.1|UniProtKB=W5MCT0 W5MCT0 PTHR48092:SF18 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 6 GROUP A MEMBER 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000015020.1|UniProtKB=W5NCY0 W5NCY0 PTHR14889:SF2 RCG36411 GENE 6377-RELATED LEPOC|Ensembl=ENSLOCG00000017116.1|UniProtKB=W5NKJ4 W5NKJ4 PTHR14015:SF0 OPIOID GROWTH FACTOR RECEPTOR OGFR ZETA-TYPE OPIOID RECEPTOR OPIOID GROWTH FACTOR RECEPTOR-LIKE PROTEIN 1 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006611.1|UniProtKB=W5MHY8 W5MHY8 PTHR11817:SF31 PYRUVATE KINASE PYRUVATE KINASE PKLR transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;pyruvate kinase activity#GO:0004743;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular response to chemical stimulus#GO:0070887;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;monocarboxylic acid metabolic process#GO:0032787;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;pyruvate metabolic process#GO:0006090;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;cellular response to oxygen-containing compound#GO:1901701;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;primary metabolic process#GO:0044238;response to insulin#GO:0032868;purine nucleoside triphosphate metabolic process#GO:0009144;cellular response to stimulus#GO:0051716;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;cellular response to insulin stimulus#GO:0032869;ADP metabolic process#GO:0046031;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;response to peptide hormone#GO:0043434;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;pyridine nucleotide catabolic process#GO:0019364;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;response to hormone#GO:0009725;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;response to chemical#GO:0042221;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;response to nitrogen compound#GO:1901698;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;cellular response to peptide hormone stimulus#GO:0071375;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;cellular response to nitrogen compound#GO:1901699;nucleobase-containing compound metabolic process#GO:0006139 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132;Glycolysis#P00024>Pyruvate kinase#P00675 LEPOC|Ensembl=ENSLOCG00000002494.1|UniProtKB=W5M3H4 W5M3H4 PTHR46258:SF3 LONGIN DOMAIN-CONTAINING PROTEIN VESICLE-TRAFFICKING PROTEIN SEC22A cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 LEPOC|Ensembl=ENSLOCG00000018152.1|UniProtKB=W5NNP4 W5NNP4 PTHR46048:SF13 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014815.1|UniProtKB=W5NC84 W5NC84 PTHR11594:SF1 40S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN ES27 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;translation#GO:0006412;nucleic acid biosynthetic process#GO:0141187 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016532.1|UniProtKB=W5NIF9 W5NIF9 PTHR42881:SF3 PROLYL ENDOPEPTIDASE PROLYL ENDOPEPTIDASE catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004605.1|UniProtKB=W5MAX6 W5MAX6 PTHR18945:SF52 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857 trans-synaptic signaling#GO:0099537;transmembrane transport#GO:0055085;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;signaling receptor complex#GO:0043235;cation channel complex#GO:0034703;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 ligand-gated ion channel#PC00141 Gonadotropin-releasing hormone receptor pathway#P06664>5-HT3AR#P06833;5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422 LEPOC|Ensembl=ENSLOCG00000017876.1|UniProtKB=W5NMX0 W5NMX0 PTHR24072:SF0 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOB hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Integrin signalling pathway#P00034>Rho#P00948;Ras Pathway#P04393>Rho#P04578;PDGF signaling pathway#P00047>Ras#P01154;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507;Angiogenesis#P00005>GTPase#P00254 LEPOC|Ensembl=ENSLOCG00000003733.1|UniProtKB=W5M7X7 W5M7X7 PTHR45761:SF3 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-1 phosphatidylcholine binding#GO:0031210;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;metal ion binding#GO:0046872;cation binding#GO:0043169;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008116.1|UniProtKB=W5MN99 W5MN99 PTHR22804:SF8 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 2 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;system development#GO:0048731;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 extracellular region#GO:0005576;cell junction#GO:0030054;cell periphery#GO:0071944;external encapsulating structure#GO:0030312;membrane#GO:0016020;extracellular matrix#GO:0031012;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000007743.1|UniProtKB=W5MLZ1 W5MLZ1 PTHR12538:SF10 40S RIBOSOMAL PROTEIN S26 40S RIBOSOMAL PROTEIN S26 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000002918.1|UniProtKB=W5M4X7 W5M4X7 PTHR22829:SF7 DEP DOMAIN PROTEIN DEP DOMAIN-CONTAINING MTOR-INTERACTING PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860 regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of TORC1 signaling#GO:1904262;regulation of TORC1 signaling#GO:1903432;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;signal transduction#GO:0007165;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000002251.1|UniProtKB=W5M2L6 W5M2L6 PTHR24100:SF145 BUTYROPHILIN CD276 ANTIGEN ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001514.1|UniProtKB=W5M040 W5M040 PTHR11229:SF8 50S RIBOSOMAL PROTEIN L3 LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000017398.1|UniProtKB=W5NLJ4 W5NLJ4 PTHR46880:SF9 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN ZINC FINGER MYM-TYPE PROTEIN 1-LIKE LEPOC|Ensembl=ENSLOCG00000000381.1|UniProtKB=W5LWB0 W5LWB0 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 structural molecule activity#GO:0005198;protein binding#GO:0005515;enzyme binding#GO:0019899;extracellular matrix structural constituent#GO:0005201;binding#GO:0005488 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;single fertilization#GO:0007338;biological regulation#GO:0065007;oogenesis#GO:0048477;regulation of reproductive process#GO:2000241;developmental process#GO:0032502;sperm-egg recognition#GO:0035036;cell-cell recognition#GO:0009988;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;fertilization#GO:0009566;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276;sexual reproduction#GO:0019953;cell recognition#GO:0008037;multicellular organismal reproductive process#GO:0048609;binding of sperm to zona pellucida#GO:0007339;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000016769.1|UniProtKB=W5NJC7 W5NJC7 PTHR11468:SF29 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, BRAIN FORM glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycogen catabolic process#GO:0005980;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;generation of precursor metabolites and energy#GO:0006091;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;glycogen metabolic process#GO:0005977;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;polysaccharide catabolic process#GO:0000272;carbohydrate catabolic process#GO:0016052;energy reserve metabolic process#GO:0006112 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718 LEPOC|Ensembl=ENSLOCG00000003864.1|UniProtKB=W5M8G9 W5M8G9 PTHR45636:SF26 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-7 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010016.1|UniProtKB=W5MV47 W5MV47 PTHR28441:SF7 PROTEIN FAM91A1 PROTEIN FAM91A1 macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000016174.1|UniProtKB=W5NH21 W5NH21 PTHR24058:SF51 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 2 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003247.1|UniProtKB=W5M635 W5M635 PTHR11616:SF306 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;sodium ion transport#GO:0006814;monoatomic cation transport#GO:0006812;localization#GO:0051179;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000004761.1|UniProtKB=W5MBF3 W5MBF3 PTHR24124:SF4 ANKYRIN REPEAT FAMILY A DNA-BINDING PROTEIN RFXANK regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017316.1|UniProtKB=W5NLB2 W5NLB2 PTHR24369:SF8 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of axonogenesis#GO:0050770;regulation of cell projection organization#GO:0031344;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of developmental process#GO:0050793;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;synaptic membrane adhesion#GO:0099560;cell adhesion#GO:0007155;synapse organization#GO:0050808;regulation of signaling#GO:0023051 postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000502.1|UniProtKB=W5LWP5 W5LWP5 PTHR11984:SF3 CONNEXIN GAP JUNCTION DELTA-4 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cell communication#GO:0007154;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular process#GO:0009987 anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000017874.1|UniProtKB=W5NMW8 W5NMW8 PTHR15462:SF17 SERINE PROTEASE INACTIVE SERINE PROTEASE 35 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000003615.1|UniProtKB=W5M7C9 W5M7C9 PTHR24070:SF221 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2A ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of locomotion#GO:0040013;small GTPase-mediated signal transduction#GO:0007264;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;regulation of locomotion#GO:0040012;regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 LEPOC|Ensembl=ENSLOCG00000005057.1|UniProtKB=W5MCI0 W5MCI0 PTHR11618:SF77 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION INITIATION FACTOR IIB sequence-specific double-stranded DNA binding#GO:1990837;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transcription factor binding#GO:0008134;catalytic activity#GO:0003824;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;acyltransferase activity#GO:0016746;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;transferase activity#GO:0016740;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;acetyltransferase activity#GO:0016407 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;gene expression#GO:0010467;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 General transcription regulation#P00023>TFIIB#P00668;Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397 LEPOC|Ensembl=ENSLOCG00000001244.1|UniProtKB=W5LZ52 W5LZ52 PTHR34488:SF1 SI:CH211-245H14.1-RELATED SI:CH211-245H14.1-RELATED LEPOC|Ensembl=ENSLOCG00000008691.1|UniProtKB=W5MQB4 W5MQB4 PTHR15813:SF10 SORTING NEXIN-22 AND 24 SORTING NEXIN-24 phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015404.1|UniProtKB=W5NE92 W5NE92 PTHR45644:SF8 AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED OUTER MITOCHONDRIAL TRANSMEMBRANE HELIX TRANSLOCASE cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;localization within membrane#GO:0051668;establishment of protein localization#GO:0045184 LEPOC|Ensembl=ENSLOCG00000012776.1|UniProtKB=W5N510 W5N510 PTHR46771:SF3 DETERIN BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5 mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;negative regulation of apoptotic process#GO:0043066;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton-dependent cytokinesis#GO:0061640;microtubule cytoskeleton organization#GO:0000226;cytokinesis#GO:0000910;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;mitotic cytokinesis#GO:0000281;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell division#GO:0051301;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850 chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630 Angiogenesis#P00005>Survivin#P00198 LEPOC|Ensembl=ENSLOCG00000006563.1|UniProtKB=W5MHS0 W5MHS0 PTHR15904:SF19 FAM13 PROTEIN FAM13C LEPOC|Ensembl=ENSLOCG00000008746.1|UniProtKB=W5MQI9 W5MQI9 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007504.1|UniProtKB=W5ML49 W5ML49 PTHR18860:SF28 14-3-3 PROTEIN 14-3-3 PROTEIN BETA_ALPHA scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;Parkinson disease#P00049>14-3-3#P01238;CCKR signaling map#P06959>14-3-3 beta/alpha#P07038 LEPOC|Ensembl=ENSLOCG00000013447.1|UniProtKB=W5N7H7 W5N7H7 PTHR10877:SF114 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2 potassium channel activity#GO:0005267;ion binding#GO:0043167;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;cation binding#GO:0043169;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated calcium channel activity#GO:0005245;sodium channel activity#GO:0005272;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;calcium ion binding#GO:0005509;gated channel activity#GO:0022836;binding#GO:0005488;voltage-gated monoatomic ion channel activity#GO:0005244;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;metal ion binding#GO:0046872;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 response to abiotic stimulus#GO:0009628;calcium ion transmembrane transport#GO:0070588;response to stimulus#GO:0050896;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;detection of stimulus#GO:0051606;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;response to mechanical stimulus#GO:0009612;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;detection of mechanical stimulus#GO:0050982;transport#GO:0006810;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000011751.1|UniProtKB=W5N1D9 W5N1D9 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 protease#PC00190;aspartic protease#PC00053 LEPOC|Ensembl=ENSLOCG00000003524.1|UniProtKB=W5M769 W5M769 PTHR19134:SF207 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE U phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 anatomical structure development#GO:0048856;cell communication#GO:0007154;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001057.1|UniProtKB=W5LYI3 W5LYI3 PTHR46985:SF2 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD pattern recognition receptor activity#GO:0038187;enzyme regulator activity#GO:0030234;molecular transducer activity#GO:0060089;molecular function activator activity#GO:0140677;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;signaling receptor activity#GO:0038023;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;peptidase activator activity#GO:0016504 positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;regulation of innate immune response#GO:0045088;apoptotic signaling pathway#GO:0097190;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;inflammatory response#GO:0006954;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;intrinsic apoptotic signaling pathway#GO:0097193 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;canonical inflammasome complex#GO:0061702;intracellular organelle#GO:0043229 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001777.1|UniProtKB=W5M103 W5M103 PTHR45674:SF15 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 1 catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;cell cycle process#GO:0022402;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;DNA strand elongation involved in DNA replication#GO:0006271;mitotic cell cycle#GO:0000278;DNA-templated DNA replication#GO:0006261 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009;DNA ligase#PC00012 LEPOC|Ensembl=ENSLOCG00000008121.1|UniProtKB=W5MNB2 W5MNB2 PTHR10194:SF21 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 2 GTPase-activating protein#PC00257 FGF signaling pathway#P00021>RasGAP#P00646;PDGF signaling pathway#P00047>RasGAP#P01152;EGF receptor signaling pathway#P00018>GAP#P00546 LEPOC|Ensembl=ENSLOCG00000005815.1|UniProtKB=W5MF65 W5MF65 PTHR11620:SF2 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001892.1|UniProtKB=W5M1D7 W5M1D7 PTHR23352:SF2 NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN-1 NPDC-1 PROTEIN NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000012384.1|UniProtKB=W5N3N9 W5N3N9 PTHR18945:SF218 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-2 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;neurotransmitter receptor activity#GO:0030594;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;synapse assembly#GO:0007416;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;chloride transport#GO:0006821;nervous system development#GO:0007399;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;cellular process#GO:0009987;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;cell junction#GO:0030054;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000018338.1|UniProtKB=W5NP80 W5NP80 PTHR10270:SF27 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-4 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;camera-type eye morphogenesis#GO:0048593;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;sensory organ development#GO:0007423;negative regulation of cellular process#GO:0048523;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;camera-type eye development#GO:0043010;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;sensory system development#GO:0048880;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;sensory organ morphogenesis#GO:0090596;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;eye development#GO:0001654;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000000793.1|UniProtKB=W5LXM2 W5LXM2 PTHR31193:SF1 TRANSMEMBRANE PROTEIN C9ORF91 TRANSMEMBRANE PROTEIN 268 LEPOC|Ensembl=ENSLOCG00000006139.1|UniProtKB=W5MGB0 W5MGB0 PTHR46222:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP14 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008628.1|UniProtKB=W5MQ46 W5MQ46 PTHR13743:SF64 BEIGE/BEACH-RELATED LIPOPOLYSACCHARIDE-RESPONSIVE AND BEIGE-LIKE ANCHOR PROTEIN protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cell junction organization#GO:0034330;catabolic process#GO:0009056;cellular component organization#GO:0016043;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;synapse organization#GO:0050808;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013058.1|UniProtKB=W5N622 W5N622 PTHR12842:SF4 FI01459P PROTEIN NOXP20 LEPOC|Ensembl=ENSLOCG00000008554.1|UniProtKB=W5MPV0 W5MPV0 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to other organism#GO:0051707;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005638.1|UniProtKB=W5MEJ8 W5MEJ8 PTHR31169:SF24 OS05G0300700 PROTEIN CELL DIVISION CYCLE-ASSOCIATED PROTEIN 7 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000006003.1|UniProtKB=W5MFU5 W5MFU5 PTHR31848:SF0 REFILIN-A-RELATED REFILIN-A anatomical structure development#GO:0048856;skeletal system development#GO:0001501;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of bone mineralization#GO:0030500;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;skeletal system morphogenesis#GO:0048705;regulation of cell development#GO:0060284 LEPOC|Ensembl=ENSLOCG00000015354.1|UniProtKB=W5NE36 W5NE36 PTHR44414:SF1 PROTEIN NEDD1 PROTEIN NEDD1 protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;mitotic cell cycle#GO:0000278;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;spindle pole#GO:0000922;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000001693.1|UniProtKB=W5M0Q6 W5M0Q6 PTHR10747:SF36 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;P53-like transcription factor#PC00253 LEPOC|Ensembl=ENSLOCG00000005625.1|UniProtKB=W5MEJ3 W5MEJ3 PTHR24412:SF174 KELCH PROTEIN KELCH-LIKE ECH-ASSOCIATED PROTEIN 1A ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016759.1|UniProtKB=W5NJA2 W5NJA2 PTHR28457:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 SIMILAR TO HUMAN CHROMOSOME 8 OPEN READING FRAME 74 LEPOC|Ensembl=ENSLOCG00000009286.1|UniProtKB=W5MSH8 W5MSH8 PTHR47633:SF21 IMMUNOGLOBULIN STRIATED MUSCLE PREFERENTIALLY EXPRESSED PROTEIN KINASE-RELATED LEPOC|Ensembl=ENSLOCG00000014219.1|UniProtKB=W5NA52 W5NA52 PTHR10589:SF28 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE BAP1 cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000011820.1|UniProtKB=W5N1M8 W5N1M8 PTHR43880:SF3 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE 6-RELATED transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022 aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;aldehyde catabolic process#GO:0046185;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;metabolic process#GO:0008152;cellular detoxification of aldehyde#GO:0110095;cellular response to stimulus#GO:0051716;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000017250.1|UniProtKB=W5NL27 W5NL27 PTHR45716:SF3 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 1 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;exocytosis#GO:0006887;secretion by cell#GO:0032940 plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000010968.1|UniProtKB=W5MYJ4 W5MYJ4 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H6 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018117.1|UniProtKB=W5NNK9 W5NNK9 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000012792.1|UniProtKB=W5N536 W5N536 PTHR24409:SF331 ZINC FINGER PROTEIN 142 C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008921.1|UniProtKB=W5MR59 W5MR59 PTHR16026:SF5 CARTILAGE ACIDIC PROTEIN 1 CARTILAGE ACIDIC PROTEIN 1 neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;cell recognition#GO:0008037;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;axon development#GO:0061564;neuron projection development#GO:0031175 LEPOC|Ensembl=ENSLOCG00000010100.1|UniProtKB=W5MVF2 W5MVF2 PTHR45629:SF16 SNF2/RAD54 FAMILY MEMBER DNA REPAIR AND RECOMBINATION PROTEIN RAD54B catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;DNA translocase activity#GO:0015616;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;DNA recombination#GO:0006310;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;homologous recombination#GO:0035825;reproductive process#GO:0022414;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000008697.1|UniProtKB=W5MQB9 W5MQB9 PTHR34914:SF1 LYMPHOCYTE EXPANSION MOLECULE CILIARY MICROTUBULE-ASSOCIATED PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000000281.1|UniProtKB=W5LW07 W5LW07 PTHR43775:SF56 FATTY ACID SYNTHASE FATTY ACID SYNTHASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000016772.1|UniProtKB=W5NJC2 W5NJC2 PTHR10515:SF0 THYMIDINE PHOSPHORYLASE THYMIDINE PHOSPHORYLASE pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 glycosyltransferase#PC00111 Salvage pyrimidine deoxyribonucleotides#P02774>Uracil phosphorylase#P03145;Pyrimidine Metabolism#P02771>Nucleoside Phosphorylase#P03126;Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine phosphorylase#P03148 LEPOC|Ensembl=ENSLOCG00000006947.1|UniProtKB=W5MJ46 W5MJ46 PTHR24064:SF460 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000002632.1|UniProtKB=W5M3Z2 W5M3Z2 PTHR11232:SF35 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER LOW DENSITY LIPOPROTEIN RECEPTOR ADAPTER PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 regulation of biological process#GO:0050789;cellular process#GO:0009987;receptor internalization#GO:0031623;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;endocytosis#GO:0006897;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;plasma lipoprotein particle clearance#GO:0034381;establishment of localization#GO:0051234;import into cell#GO:0098657 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002150.1|UniProtKB=W5M2B5 W5M2B5 PTHR11590:SF70 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 4 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000002517.1|UniProtKB=W5M3K3 W5M3K3 PTHR45904:SF2 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000013545.1|UniProtKB=W5N7T9 W5N7T9 PTHR31882:SF6 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 2 response to bacterium#GO:0009617;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207;positive regulation of cell communication#GO:0010647;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stress#GO:0080134;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;positive regulation of innate immune response#GO:0045089;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;cell surface receptor signaling pathway#GO:0007166;positive regulation of response to external stimulus#GO:0032103;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;response to chemical#GO:0042221;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;positive regulation of signal transduction#GO:0009967;innate immune response-activating signaling pathway#GO:0002758;regulation of cell communication#GO:0010646;intracellular receptor signaling pathway#GO:0030522;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;response to lipopolysaccharide#GO:0032496;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;regulation of response to external stimulus#GO:0032101;cellular response to lipid#GO:0071396 LEPOC|Ensembl=ENSLOCG00000006842.1|UniProtKB=W5MIS3 W5MIS3 PTHR11827:SF54 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 5 symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;chloride transport#GO:0006821;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 neuron projection#GO:0043005;cell body#GO:0044297;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000015215.1|UniProtKB=W5NDL5 W5NDL5 PTHR21646:SF16 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 39 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;regulation of protein stability#GO:0031647;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000016661.1|UniProtKB=W5NIX2 W5NIX2 PTHR24058:SF136 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013112.1|UniProtKB=W5N693 W5N693 PTHR24161:SF110 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PRE-MRNA SPLICING REGULATOR USH1G protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001661.1|UniProtKB=W5M0L3 W5M0L3 PTHR24347:SF371 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012601.1|UniProtKB=W5N4G3 W5N4G3 PTHR11616:SF277 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814 plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000011770.1|UniProtKB=W5N1H0 W5N1H0 PTHR12103:SF17 5'-NUCLEOTIDASE DOMAIN-CONTAINING CYTOSOLIC PURINE 5'-NUCLEOTIDASE phosphoric ester hydrolase activity#GO:0042578;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;kinase activity#GO:0016301;phosphatase activity#GO:0016791;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;nucleobase-containing compound kinase activity#GO:0019205;5'-nucleotidase activity#GO:0008253 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;IMP metabolic process#GO:0046040;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000002411.1|UniProtKB=W5M369 W5M369 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010400.1|UniProtKB=W5MWJ7 W5MWJ7 PTHR10201:SF26 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-16 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 developmental process#GO:0032502;metabolic process#GO:0008152;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;system development#GO:0048731;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000017575.1|UniProtKB=W5NM21 W5NM21 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002478.1|UniProtKB=W5M3F8 W5M3F8 PTHR21242:SF0 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;peptidase complex#GO:1905368;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transcription factor TFIID complex#GO:0005669;SAGA complex#GO:0000124;chromatin#GO:0000785;acetyltransferase complex#GO:1902493;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016820.1|UniProtKB=W5NJI0 W5NJI0 PTHR12588:SF0 MYOINOSITOL OXYGENASE INOSITOL OXYGENASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000006857.1|UniProtKB=W5MIT3 W5MIT3 PTHR22750:SF38 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002716.1|UniProtKB=W5M4A2 W5M4A2 PTHR10125:SF9 P2X PURINOCEPTOR P2X PURINOCEPTOR 1 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000016727.1|UniProtKB=W5NJ60 W5NJ60 PTHR16768:SF1 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A PROTEIN FAM107B LEPOC|Ensembl=ENSLOCG00000018325.1|UniProtKB=W5NP67 W5NP67 PTHR48051:SF36 FAMILY NOT NAMED LEUCINE-RICH REPEAT PROTEIN SOC-2 HOMOLOG intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001741.1|UniProtKB=W5M0V8 W5M0V8 PTHR10417:SF2 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000012291.1|UniProtKB=W5N3C0 W5N3C0 PTHR11243:SF25 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;negative regulation of cellular process#GO:0048523;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Grb7#P00228 LEPOC|Ensembl=ENSLOCG00000008037.1|UniProtKB=W5MN14 W5MN14 PTHR31859:SF7 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39A LEPOC|Ensembl=ENSLOCG00000014045.1|UniProtKB=W5N9K0 W5N9K0 PTHR24237:SF44 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 6 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001801.1|UniProtKB=W5M158 W5M158 PTHR24346:SF119 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE SIK3 HOMOLOG-RELATED protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012710.1|UniProtKB=W5N4T3 W5N4T3 PTHR24006:SF653 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of protein stability#GO:0031647;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007567.1|UniProtKB=W5MLC2 W5MLC2 PTHR10619:SF0 F-ACTIN-CAPPING PROTEIN SUBUNIT BETA F-ACTIN-CAPPING PROTEIN SUBUNIT BETA ISOFORMS 1 AND 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament depolymerization#GO:0030834;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;regulation of protein depolymerization#GO:1901879;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970 cell periphery#GO:0071944;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000005828.1|UniProtKB=W5MF80 W5MF80 PTHR24031:SF2 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX55 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007207.1|UniProtKB=W5MK14 W5MK14 PTHR20275:SF29 NAD KINASE NAD(+) KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000014060.1|UniProtKB=W5N9L6 W5N9L6 PTHR15159:SF2 NEUROSECRETORY PROTEIN VGF NEUROSECRETORY PROTEIN VGF neuropeptide hormone activity#GO:0005184;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of neuronal synaptic plasticity#GO:0048168;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000006856.1|UniProtKB=W5MIS6 W5MIS6 PTHR14487:SF3 ADRENOCORTICAL DYSPLASIA PROTEIN ACD ADRENOCORTICAL DYSPLASIA PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000014991.1|UniProtKB=W5NCU7 W5NCU7 PTHR11267:SF116 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX22 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;cell fate specification#GO:0001708;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 LEPOC|Ensembl=ENSLOCG00000017691.1|UniProtKB=W5NMD7 W5NMD7 PTHR40472:SF9 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 4 LEPOC|Ensembl=ENSLOCG00000009720.1|UniProtKB=W5MU13 W5MU13 PTHR46636:SF1 CDK2-ASSOCIATED AND CULLIN DOMAIN-CONTAINING PROTEIN 1 CDK2-ASSOCIATED AND CULLIN DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488 cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047 LEPOC|Ensembl=ENSLOCG00000000924.1|UniProtKB=W5LY23 W5LY23 PTHR11216:SF127 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection organization#GO:0120036;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;organelle assembly#GO:0070925;endocytosis#GO:0006897;cell projection organization#GO:0030030;endocytic recycling#GO:0032456;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;recycling endosome#GO:0055037;organelle membrane#GO:0031090;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002938.1|UniProtKB=W5M526 W5M526 PTHR22619:SF2 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 5 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000001857.1|UniProtKB=W5M1B3 W5M1B3 PTHR22750:SF49 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008655.1|UniProtKB=W5MQ70 W5MQ70 PTHR23510:SF16 INNER MEMBRANE TRANSPORT PROTEIN YAJR MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003522.1|UniProtKB=W5M755 W5M755 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012435.1|UniProtKB=W5N3W5 W5N3W5 PTHR24092:SF221 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IA intramembrane lipid carrier activity#GO:0140303;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000014049.1|UniProtKB=W5N9K7 W5N9K7 PTHR11878:SF7 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER 3 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;export from cell#GO:0140352;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;sodium ion transport#GO:0006814;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 axon#GO:0030424;sarcolemma#GO:0042383;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009161.1|UniProtKB=W5MS14 W5MS14 PTHR15904:SF18 FAM13 PROTEIN FAM13A LEPOC|Ensembl=ENSLOCG00000006118.1|UniProtKB=W5MG85 W5MG85 PTHR11232:SF70 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PTB DOMAIN-CONTAINING ENGULFMENT ADAPTER PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 phagocytosis#GO:0006909;transport#GO:0006810;membrane invagination#GO:0010324;import into cell#GO:0098657;establishment of localization#GO:0051234;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular component organization#GO:0016043;cellular process#GO:0009987;endocytosis#GO:0006897;membrane organization#GO:0061024 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005538.1|UniProtKB=W5ME76 W5ME76 PTHR48092:SF6 KNIRPS-RELATED PROTEIN-RELATED PROGESTERONE RECEPTOR sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular response to steroid hormone stimulus#GO:0071383;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;intracellular receptor signaling pathway#GO:0030522;response to steroid hormone#GO:0048545;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>PR#P06708 LEPOC|Ensembl=ENSLOCG00000008606.1|UniProtKB=W5MQ02 W5MQ02 PTHR11653:SF12 PARVALBUMIN ALPHA PARVALBUMIN metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000008939.1|UniProtKB=W5MR93 W5MR93 PTHR10336:SF31 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-4 hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143 Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 LEPOC|Ensembl=ENSLOCG00000007572.1|UniProtKB=W5MLD0 W5MLD0 PTHR14942:SF21 U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 LEPOC|Ensembl=ENSLOCG00000000107.1|UniProtKB=W5LVF7 W5LVF7 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009573.1|UniProtKB=W5MTJ4 W5MTJ4 PTHR11271:SF6 GUANINE DEAMINASE GUANINE DEAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 purine-containing compound catabolic process#GO:0072523;purine nucleobase catabolic process#GO:0006145;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 deaminase#PC00088 Purine metabolism#P02769>Guanine Deaminase#P03118;Xanthine and guanine salvage pathway#P02788>Guanine deaminase#P03249 LEPOC|Ensembl=ENSLOCG00000000932.1|UniProtKB=W5LY33 W5LY33 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000445.1|UniProtKB=W5LWI2 W5LWI2 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014196.1|UniProtKB=W5NA28 W5NA28 PTHR18806:SF4 RBM25 PROTEIN RNA-BINDING PROTEIN 25 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468 LEPOC|Ensembl=ENSLOCG00000015123.1|UniProtKB=W5NDA3 W5NDA3 PTHR12241:SF161 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL6 binding#GO:0005488;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 microtubule bundle formation#GO:0001578;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005641.1|UniProtKB=W5MEJ9 W5MEJ9 PTHR24240:SF90 OPSIN RPE-RETINAL G PROTEIN-COUPLED RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to radiation#GO:0071478;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;signal transduction#GO:0007165;detection of stimulus#GO:0051606;biological regulation#GO:0065007;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006017.1|UniProtKB=W5MFW5 W5MFW5 PTHR10742:SF342 FLAVIN MONOAMINE OXIDASE L-AMINO-ACID OXIDASE ISOFORM X1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056 oxidase#PC00175 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 LEPOC|Ensembl=ENSLOCG00000003299.1|UniProtKB=W5M683 W5M683 PTHR24346:SF44 MAP/MICROTUBULE AFFINITY-REGULATING KINASE N-LYSINE METHYLTRANSFERASE SETD6 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002623.1|UniProtKB=W5M3Y0 W5M3Y0 PTHR12349:SF4 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899 mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;membrane assembly#GO:0071709;organelle fission#GO:0048285;nuclear division#GO:0000280;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;nuclear envelope organization#GO:0006998;mitotic cell cycle process#GO:1903047 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000017730.1|UniProtKB=W5NMH5 W5NMH5 PTHR13627:SF31 FUKUTIN RELATED PROTEIN RIBITOL 5-PHOSPHATE TRANSFERASE FKRP phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006126.1|UniProtKB=W5MG93 W5MG93 PTHR10489:SF936 CELL ADHESION MOLECULE G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017678.1|UniProtKB=W5NMC4 W5NMC4 PTHR46314:SF2 SOLUTE CARRIER FAMILY 25 MEMBER 44 SOLUTE CARRIER FAMILY 25 MEMBER 44 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;branched-chain amino acid transmembrane transporter activity#GO:0015658 branched-chain amino acid transport#GO:0015803;localization#GO:0051179;establishment of localization#GO:0051234;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;nitrogen compound transport#GO:0071705 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000000060.1|UniProtKB=W5LVB3 W5LVB3 PTHR33775:SF4 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED SIMILAR TO HUMAN CHROMOSOME 4 OPEN READING FRAME 54 LEPOC|Ensembl=ENSLOCG00000012603.1|UniProtKB=W5N4G0 W5N4G0 PTHR46467:SF1 TETHER CONTAINING UBX DOMAIN FOR GLUT4 TETHER CONTAINING UBX DOMAIN FOR GLUT4 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;glucose homeostasis#GO:0042593;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular protein transport#GO:0006886;homeostatic process#GO:0042592;carbohydrate homeostasis#GO:0033500;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000004864.1|UniProtKB=W5MBT6 W5MBT6 PTHR24300:SF319 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;tetrapyrrole binding#GO:0046906;binding#GO:0005488 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000002635.1|UniProtKB=W5M3Y7 W5M3Y7 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016430.1|UniProtKB=W5NI51 W5NI51 PTHR14387:SF7 THADA/DEATH RECEPTOR INTERACTING PROTEIN TRNA (32-2'-O)-METHYLTRANSFERASE REGULATOR THADA molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;tRNA methylation#GO:0030488;monoatomic ion homeostasis#GO:0050801;intracellular calcium ion homeostasis#GO:0006874;tRNA processing#GO:0008033;chemical homeostasis#GO:0048878;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA modification#GO:0006400;intracellular monoatomic ion homeostasis#GO:0006873;RNA metabolic process#GO:0016070;methylation#GO:0032259;inorganic ion homeostasis#GO:0098771;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;calcium ion homeostasis#GO:0055074;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;macromolecule metabolic process#GO:0043170;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;homeostatic process#GO:0042592;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;RNA methylation#GO:0001510 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004690.1|UniProtKB=W5MB61 W5MB61 PTHR10093:SF8 IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG IRON-SULFUR CLUSTER ASSEMBLY ENZYME ISCU iron ion binding#GO:0005506;ferrous iron binding#GO:0008198;metal ion binding#GO:0046872;iron-sulfur cluster binding#GO:0051536;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011385.1|UniProtKB=W5N036 W5N036 PTHR12010:SF2 40S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN US14 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;zinc ion binding#GO:0008270;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001414.1|UniProtKB=W5LZQ7 W5LZQ7 PTHR12247:SF69 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 1 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014546.1|UniProtKB=W5NBA9 W5NBA9 PTHR21597:SF0 THO2 PROTEIN THO COMPLEX SUBUNIT 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular organelle#GO:0043229;transcription export complex#GO:0000346;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000015149.1|UniProtKB=W5NDD3 W5NDD3 LSM1 PTHR15588:SF8 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000002007.1|UniProtKB=W5M1R9 W5M1R9 PTHR45729:SF9 RABPHILIN, ISOFORM A DOUBLE C2-LIKE DOMAIN-CONTAINING PROTEIN BETA regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of exocytosis#GO:0017157;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;positive regulation of cellular process#GO:0048522;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;positive regulation of secretion#GO:0051047;positive regulation of cellular component organization#GO:0051130;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;synaptic signaling#GO:0099536;regulation of transport#GO:0051049;exocytosis#GO:0006887;regulation of localization#GO:0032879;positive regulation of vesicle fusion#GO:0031340;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000013807.1|UniProtKB=W5N8R8 W5N8R8 PTHR15726:SF5 RAB11-FAMILY INTERACTING PROTEIN RAB11 FAMILY-INTERACTING PROTEIN 4 regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;endocytic recycling#GO:0032456;regulation of biological process#GO:0050789;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302 endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;midbody#GO:0030496;vesicle#GO:0031982;cleavage furrow#GO:0032154;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;recycling endosome#GO:0055037;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cell division site#GO:0032153;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000013968.1|UniProtKB=W5N9A7 W5N9A7 PTHR33963:SF2 MKRN2 OPPOSITE STRAND PROTEIN MKRN2 OPPOSITE STRAND PROTEIN LEPOC|Ensembl=ENSLOCG00000006905.1|UniProtKB=W5MIZ3 W5MIZ3 PTHR12932:SF24 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;protein polymerization#GO:0051258;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;microtubule bundle formation#GO:0001578;positive regulation of cellular component organization#GO:0051130;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of protein polymerization#GO:0032273;cellular component assembly#GO:0022607;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000004037.1|UniProtKB=W5M8X6 W5M8X6 PTHR46108:SF3 BLUE CHEESE WD REPEAT- AND FYVE DOMAIN-CONTAINING PROTEIN 4 immune system process#GO:0002376;antigen processing and presentation#GO:0019882 LEPOC|Ensembl=ENSLOCG00000015249.1|UniProtKB=W5NDR2 W5NDR2 PTHR20856:SF8 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;snRNA transcription#GO:0009301;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;snRNA transcription by RNA polymerase III#GO:0042796;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000004598.1|UniProtKB=W5MAV2 W5MAV2 PTHR13372:SF4 GEMININ GEMININ transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated DNA replication initiation#GO:0030174;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;negative regulation of cell cycle#GO:0045786;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of cell cycle#GO:0051726;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA replication#GO:0006275;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000000640.1|UniProtKB=W5LX50 W5LX50 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013042.1|UniProtKB=W5N625 W5N625 PTHR13800:SF8 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 7 channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;kinase activity#GO:0016301;transporter activity#GO:0005215;transferase activity#GO:0016740 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015316.1|UniProtKB=W5NDY9 W5NDY9 PTHR10672:SF6 ADDUCIN BETA-ADDUCIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of protein depolymerization#GO:1901879;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903 synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000018105.1|UniProtKB=W5NNJ7 W5NNJ7 PTHR10155:SF4 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 1 signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;protein binding#GO:0005515 signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;response to peptide#GO:1901652;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;response to cytokine#GO:0034097;response to chemical#GO:0042221;negative regulation of response to stimulus#GO:0048585;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 kinase modulator#PC00140 JAK/STAT signaling pathway#P00038>SOCS#P01030 LEPOC|Ensembl=ENSLOCG00000017797.1|UniProtKB=W5NMP2 W5NMP2 PTHR12277:SF207 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD13 catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000001239.1|UniProtKB=W5LZ44 W5LZ44 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000011165.1|UniProtKB=W5MZA8 W5MZA8 PTHR23037:SF63 CYTOKINE RECEPTOR INTERLEUKIN 2 RECEPTOR, GAMMA B ISOFORM X1-RELATED immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;immune system process#GO:0002376;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;cell communication#GO:0007154;response to peptide#GO:1901652;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;response to cytokine#GO:0034097;response to chemical#GO:0042221;adaptive immune response#GO:0002250;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;immune effector process#GO:0002252 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006960.1|UniProtKB=W5MJ55 W5MJ55 PTHR11712:SF362 POLYKETIDE SYNTHASE-RELATED 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330 LEPOC|Ensembl=ENSLOCG00000016596.1|UniProtKB=W5NIP1 W5NIP1 PTHR24075:SF0 SEC63 DOMAIN-CONTAINING TRANSLOCATION PROTEIN SEC63 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;rough endoplasmic reticulum#GO:0005791;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003237.1|UniProtKB=W5M612 W5M612 PTHR46600:SF14 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004177.1|UniProtKB=W5M9D3 W5M9D3 PTHR20859:SF46 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON GAMMA RECEPTOR 2 cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Interferon-gamma signaling pathway#P00035>IFNGR1#P00959;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866;Interferon-gamma signaling pathway#P00035>IFNGR2#P00957 LEPOC|Ensembl=ENSLOCG00000000507.1|UniProtKB=W5LWQ0 W5LWQ0 PTHR14819:SF5 GTP-BINDING INTERFERON-INDUCED VERY LARGE GTPASE 1 LEPOC|Ensembl=ENSLOCG00000006039.1|UniProtKB=W5MFY9 W5MFY9 PTHR11328:SF31 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN SODIUM-DEPENDENT LYSOPHOSPHATIDYLCHOLINE SYMPORTER 1 lipid transport#GO:0006869;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;lipid localization#GO:0010876;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000017293.1|UniProtKB=W5NL89 W5NL89 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000009924.1|UniProtKB=W5MUT9 W5MUT9 PTHR10814:SF29 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 1 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 LEPOC|Ensembl=ENSLOCG00000002785.1|UniProtKB=W5M4G5 W5M4G5 PTHR23148:SF0 SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000008021.1|UniProtKB=W5MMY9 W5MMY9 PTHR12917:SF13 ASPARTYL PROTEASE DDI-RELATED PROTEIN DDI1 HOMOLOG 2 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 regulation of protein stability#GO:0031647;cellular process#GO:0009987;primary metabolic process#GO:0044238;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule catabolic process#GO:0009057;regulation of biological quality#GO:0065008;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010812.1|UniProtKB=W5MXZ9 W5MXZ9 PTHR24161:SF131 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED M-PHASE PHOSPHOPROTEIN 8 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009330.1|UniProtKB=W5MSM5 W5MSM5 PTHR11153:SF17 SIDEROFLEXIN SIDEROFLEXIN-5 citrate transmembrane transporter activity#GO:0015137;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial transport#GO:0006839;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810;tricarboxylic acid transport#GO:0006842;intracellular transport#GO:0046907;citrate transport#GO:0015746;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000003881.1|UniProtKB=W5M8C9 W5M8C9 PTHR46376:SF1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Ras protein signal transduction#GO:0046578;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 transferase complex#GO:1990234;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;recycling endosome membrane#GO:0055038;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Cul3-RING ubiquitin ligase complex#GO:0031463;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000000767.1|UniProtKB=W5LXJ2 W5LXJ2 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011585.1|UniProtKB=W5N0S6 W5N0S6 PTHR28664:SF2 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 BRAIN-ENRICHED GUANYLATE KINASE-ASSOCIATED PROTEIN nervous system process#GO:0050877;trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of postsynaptic membrane potential#GO:0060078;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;chemical synaptic transmission, postsynaptic#GO:0099565;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;system process#GO:0003008;regulation of membrane potential#GO:0042391;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000004957.1|UniProtKB=W5MC55 W5MC55 PTHR11977:SF142 VILLIN PROTEIN FLIGHTLESS-1 HOMOLOG cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;actin filament binding#GO:0051015;actin binding#GO:0003779;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936 negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular component organization#GO:0051128;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;striated muscle cell development#GO:0055002;regulation of biological quality#GO:0065008;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular anatomical entity morphogenesis#GO:0032989;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;negative regulation of organelle organization#GO:0010639;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of actin filament depolymerization#GO:0030834;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;anatomical structure development#GO:0048856;negative regulation of protein-containing complex assembly#GO:0031333;actin polymerization or depolymerization#GO:0008154;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;negative regulation of actin filament depolymerization#GO:0030835;regulation of protein-containing complex disassembly#GO:0043244;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;myofibril assembly#GO:0030239;actin cytoskeleton organization#GO:0030036;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;organelle assembly#GO:0070925;actin filament capping#GO:0051693;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;supramolecular fiber organization#GO:0097435;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;cellular developmental process#GO:0048869 nucleus#GO:0005634;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000001127.1|UniProtKB=W5LYR0 W5LYR0 PTHR46440:SF1 HOMEOBOX PROTEIN HOX-D12-RELATED HOMEOBOX PROTEIN HOX-D12 double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006966.1|UniProtKB=W5MJ71 W5MJ71 PTHR24286:SF101 CYTOCHROME P450 26 CYTOCHROME P450 26A1 monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;monocarboxylic acid catabolic process#GO:0072329;hormone metabolic process#GO:0042445;lipid metabolic process#GO:0006629;developmental process#GO:0032502;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;multicellular organism development#GO:0007275;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;central nervous system development#GO:0007417;small molecule metabolic process#GO:0044281;terpenoid metabolic process#GO:0006721;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856;isoprenoid metabolic process#GO:0006720 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000006321.1|UniProtKB=W5MGZ0 W5MGZ0 PTHR24353:SF68 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Endothelin signaling pathway#P00019>PKG#P00567;CCKR signaling map#P06959>cGK 1#P07149 LEPOC|Ensembl=ENSLOCG00000004020.1|UniProtKB=W5M8U2 W5M8U2 PTHR46639:SF2 DIENCEPHALON/MESENCEPHALON HOMEOBOX PROTEIN 1 DIENCEPHALON_MESENCEPHALON HOMEOBOX PROTEIN 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013243.1|UniProtKB=W5N6Q7 W5N6Q7 PTHR43802:SF1 ENOYL-COA HYDRATASE IP11341P-RELATED hydratase#PC00120;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004898.1|UniProtKB=W5MBX3 W5MBX3 PTHR46985:SF8 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD-RELATED molecular function activator activity#GO:0140677;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;signaling receptor activity#GO:0038023;peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047 apoptotic process#GO:0006915;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;regulation of defense response#GO:0031347;inflammatory response#GO:0006954;regulation of immune response#GO:0050776;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;apoptotic signaling pathway#GO:0097190;regulation of innate immune response#GO:0045088;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;canonical inflammasome complex#GO:0061702;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008675.1|UniProtKB=W5MQ88 W5MQ88 PTHR28626:SF3 SRR1-LIKE PROTEIN SRR1-LIKE PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000005077.1|UniProtKB=W5MCL1 W5MCL1 PTHR24356:SF322 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;PDGF signaling pathway#P00047>PKC#P01150;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 LEPOC|Ensembl=ENSLOCG00000013965.1|UniProtKB=W5N9B6 W5N9B6 PTHR45623:SF9 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD3 ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;histone binding#GO:0042393;DNA binding#GO:0003677;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001850.1|UniProtKB=W5M187 W5M187 PTHR15605:SF2 KINESIN-ASSOCIATED PROTEINS KINESIN-ASSOCIATED PROTEIN 3 microtubule-based process#GO:0007017;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000009024.1|UniProtKB=W5MRI5 W5MRI5 PTHR45758:SF20 MITOFERRIN-1-RELATED MITOFERRIN-2 metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;iron ion transmembrane transporter activity#GO:0005381;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915 iron ion transmembrane transport#GO:0034755;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967 LEPOC|Ensembl=ENSLOCG00000018120.1|UniProtKB=W5NNL2 W5NNL2 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005430.1|UniProtKB=W5MDT8 W5MDT8 PTHR31816:SF3 MICOS COMPLEX SUBUNIT MIC13 MICOS COMPLEX SUBUNIT MIC13 mitochondrion organization#GO:0007005;membrane organization#GO:0061024;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane contact site#GO:0044232;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001941.1|UniProtKB=W5M1I8 W5M1I8 PTHR11266:SF8 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN 2 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014997.1|UniProtKB=W5NCV9 W5NCV9 PTHR11909:SF156 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 LEPOC|Ensembl=ENSLOCG00000016629.1|UniProtKB=W5NIT2 W5NIT2 PTHR16290:SF5 TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 MRNA-DECAPPING ENZYME 1B nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;RNA decapping#GO:0110154;RNA catabolic process#GO:0006401;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188 cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;mRNA capping factor#PC00145 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000001586.1|UniProtKB=W5M0B5 W5M0B5 PTHR13814:SF15 FETUIN SI:CH211-262H13.5 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000009048.1|UniProtKB=W5MRL5 W5MRL5 PTHR48030:SF7 SPLICING FACTOR 3B SUBUNIT 4 SPLICING FACTOR 3B SUBUNIT 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000003918.1|UniProtKB=W5M8N0 W5M8N0 PTHR11347:SF196 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 9A ISOFORM X1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 ribonucleotide metabolic process#GO:0009259;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;nucleotide metabolic process#GO:0009117;negative regulation of cell communication#GO:0010648;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;negative regulation of signal transduction#GO:0009968;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;regulation of cellular process#GO:0050794;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;nucleotide catabolic process#GO:0009166;regulation of response to stimulus#GO:0048583;cyclic nucleotide metabolic process#GO:0009187;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;cGMP metabolic process#GO:0046068;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of signal transduction#GO:0009966 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011666.1|UniProtKB=W5N131 W5N131 PTHR13866:SF26 SPARC OSTEONECTIN SPARC cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 regulation of cellular component organization#GO:0051128;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;tube morphogenesis#GO:0035239;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;ear development#GO:0043583;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;regulation of synapse organization#GO:0050807;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;embryo development#GO:0009790;tube development#GO:0035295;inner ear morphogenesis#GO:0042472;inner ear development#GO:0048839;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;sensory organ development#GO:0007423;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000015930.1|UniProtKB=W5NG56 W5NG56 PTHR12354:SF6 INTERFERON-RELATED DEVELOPMENTAL REGULATOR INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000016705.1|UniProtKB=W5NJ28 W5NJ28 PTHR45706:SF10 TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000011230.1|UniProtKB=W5MZK1 W5MZK1 PTHR11361:SF21 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER MUTS PROTEIN HOMOLOG 4 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;meiosis I#GO:0007127;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle#GO:0007049;homologous recombination#GO:0035825;reproductive process#GO:0022414 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010178.1|UniProtKB=W5MVQ1 W5MVQ1 PTHR10361:SF19 SODIUM-BILE ACID COTRANSPORTER ILEAL SODIUM_BILE ACID COTRANSPORTER bile acid transmembrane transporter activity#GO:0015125;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;lipid transport#GO:0006869 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000016501.1|UniProtKB=W5NIC7 W5NIC7 PTHR14167:SF23 SH3 DOMAIN-CONTAINING CD2-ASSOCIATED PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007141.1|UniProtKB=W5MJT4 W5MJT4 PTHR11639:SF162 S100 CALCIUM-BINDING PROTEIN PROTEIN S100 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000004821.1|UniProtKB=W5MBN5 W5MBN5 PTHR46485:SF1 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016147.1|UniProtKB=W5NGY8 W5NGY8 PTHR10889:SF3 DEOXYRIBOSE-PHOSPHATE ALDOLASE DEOXYRIBOSE-PHOSPHATE ALDOLASE lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing small molecule catabolic process#GO:0034656;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside catabolic process#GO:0009164;metabolic process#GO:0008152 aldolase#PC00044;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000002844.1|UniProtKB=W5M4N5 W5M4N5 PTHR45787:SF3 LD11652P RHOMBOTIN-2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;embryonic organ development#GO:0048568;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000002776.1|UniProtKB=W5M4F4 W5M4F4 PTHR10423:SF3 INSULIN-LIKE 3 INSULIN-LIKE 3 molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of developmental process#GO:0050793;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of reproductive process#GO:2000241;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000007406.1|UniProtKB=W5MKT2 W5MKT2 MED17 PTHR13114:SF7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000017723.1|UniProtKB=W5NMG8 W5NMG8 PTHR24234:SF10 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006468.1|UniProtKB=W5MHF4 W5MHF4 PTHR23235:SF111 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 14 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000016405.1|UniProtKB=W5NI08 W5NI08 PTHR48041:SF71 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sterol transfer activity#GO:0120015;cholesterol transfer activity#GO:0120020;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 localization#GO:0051179;transmembrane transport#GO:0055085;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;sterol transport#GO:0015918;transport#GO:0006810;chemical homeostasis#GO:0048878;lipid transport#GO:0006869;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;cellular process#GO:0009987;cholesterol efflux#GO:0033344 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000014740.1|UniProtKB=W5NC10 W5NC10 PTHR19981:SF34 TALIN TALIN-2 integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161 LEPOC|Ensembl=ENSLOCG00000013514.1|UniProtKB=W5N7R6 W5N7R6 PTHR12860:SF0 SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68 binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization within membrane#GO:0051668;protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184 signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015791.1|UniProtKB=W5NFN0 W5NFN0 PTHR19282:SF462 TETRASPANIN TETRASPANIN-12 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017494.1|UniProtKB=W5NLU0 W5NLU0 PTHR24231:SF21 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008394.1|UniProtKB=W5MP90 W5MP90 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007712.1|UniProtKB=W5MLV5 W5MLV5 PTHR12184:SF1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000018232.1|UniProtKB=W5NNX4 W5NNX4 PTHR11863:SF213 STEROL DESATURASE CHOLESTEROL 25-HYDROXYLASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000003466.1|UniProtKB=W5M6V4 W5M6V4 PTHR31501:SF6 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 PROTEIN ORAI-3 metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000014721.1|UniProtKB=W5NBW6 W5NBW6 PTHR24240:SF19 OPSIN BLUE SENSITIVE CONE OPSIN-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;signal transduction#GO:0007165;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011348.1|UniProtKB=W5MZY4 W5MZY4 PTHR33906:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG cellular process#GO:0009987;signal transduction#GO:0007165;male gamete generation#GO:0048232;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;spermatogenesis#GO:0007283;developmental process#GO:0032502;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;gamete generation#GO:0007276;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;reproductive process#GO:0022414;signaling#GO:0023052;sexual reproduction#GO:0019953;cell communication#GO:0007154;multicellular organismal reproductive process#GO:0048609;smoothened signaling pathway#GO:0007224 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815 LEPOC|Ensembl=ENSLOCG00000002780.1|UniProtKB=W5M4H0 W5M4H0 PTHR11947:SF20 PYRUVATE DEHYDROGENASE KINASE BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010521.1|UniProtKB=W5MWY4 W5MWY4 PTHR46735:SF7 CALPAIN, SMALL SUBUNIT 1 A-RELATED SORCIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000017890.1|UniProtKB=W5NMY4 W5NMY4 PTHR24229:SF6 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2 peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;binding#GO:0005488;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide binding#GO:0042923;peptide binding#GO:0042277 cellular response to steroid hormone stimulus#GO:0071383;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;biological regulation#GO:0065007;response to estradiol#GO:0032355;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to steroid hormone#GO:0048545;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000010006.1|UniProtKB=W5MV34 W5MV34 PTHR24050:SF24 PA14 DOMAIN-CONTAINING PROTEIN EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000016697.1|UniProtKB=W5NJ23 W5NJ23 PTHR11675:SF50 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 8-RELATED polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000015664.1|UniProtKB=W5NF72 W5NF72 PTHR21096:SF0 PROTEIN FAM136A TIM DOUBLE TWIN CX3C MOTIF PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001826.1|UniProtKB=W5M179 W5M179 PTHR15075:SF5 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015558.1|UniProtKB=W5NEU2 W5NEU2 PTHR24103:SF667 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM69 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014958.1|UniProtKB=W5NCQ8 W5NCQ8 PTHR16105:SF2 RNA-BINDING REGION-CONTAINING PROTEIN 3 RNA-BINDING PROTEIN 41 LEPOC|Ensembl=ENSLOCG00000012762.1|UniProtKB=W5N501 W5N501 PTHR24351:SF200 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 response to hormone#GO:0009725;response to endogenous stimulus#GO:0009719;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to peptide hormone#GO:0043434;response to nitrogen compound#GO:1901698 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>Akt#P00589;Angiogenesis#P00005>Akt#P00223;FGF signaling pathway#P00021>Akt#P00632;Huntington disease#P00029>Akt#P00805;VEGF signaling pathway#P00056>Akt/PKB#P01408;Hypoxia response via HIF activation#P00030>AKT#P00819;EGF receptor signaling pathway#P00018>Akt#P00551;PI3 kinase pathway#P00048>PKB#P01179;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AKT#P00827;p53 pathway#P00059>Akt#P01486;FAS signaling pathway#P00020>ASK1#P00614;p53 pathway by glucose deprivation#P04397>Akt#P04641;T cell activation#P00053>Akt#P01332;p53 pathway feedback loops 2#P04398>AKT#P04665;Interleukin signaling pathway#P00036>PKB#P00973;Ras Pathway#P04393>AKT#P04570;Apoptosis signaling pathway#P00006>AKT#P00260 LEPOC|Ensembl=ENSLOCG00000001297.1|UniProtKB=W5LZB3 W5LZB3 PTHR35543:SF1 PROTEIN C11ORF74 INTRAFLAGELLAR TRANSPORT-ASSOCIATED PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 fertilization#GO:0009566;reproductive process#GO:0022414;gamete generation#GO:0007276;male gamete generation#GO:0048232;acrosome reaction#GO:0007340;single fertilization#GO:0007338;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;developmental process#GO:0032502;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283 cilium#GO:0005929;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;9+0 non-motile cilium#GO:0097731;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000014697.1|UniProtKB=W5NBT6 W5NBT6 PTHR31434:SF2 S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM LEPOC|Ensembl=ENSLOCG00000009531.1|UniProtKB=W5MTD8 W5MTD8 PTHR47333:SF6 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN-LIKE ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000005739.1|UniProtKB=W5MEX5 W5MEX5 PTHR19282:SF216 TETRASPANIN TETRASPANIN-1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008241.1|UniProtKB=W5MNP4 W5MNP4 PTHR13308:SF5 NEDD4-BINDING PROTEIN 2-LIKE 1 NEDD4-BINDING PROTEIN 2-LIKE 1 LEPOC|Ensembl=ENSLOCG00000000416.1|UniProtKB=W5LWF3 W5LWF3 PTHR16675:SF191 MHC CLASS I-RELATED CLASS I HISTOCOMPATIBILITY ANTIGEN, GOGO-C*0202 ALPHA CHAIN-LIKE-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000012581.1|UniProtKB=W5N4C8 W5N4C8 PTHR23356:SF16 DPY30-RELATED DPY30 DOMAIN-CONTAINING PROTEIN 1 plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000007698.1|UniProtKB=W5MLT8 W5MLT8 PTHR23426:SF78 FERREDOXIN/ADRENODOXIN FERREDOXIN-2, MITOCHONDRIAL metabolic process#GO:0008152;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FDX#P04607 LEPOC|Ensembl=ENSLOCG00000002666.1|UniProtKB=W5M424 W5M424 PTHR12485:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 7 mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017104.1|UniProtKB=W5NKH6 W5NKH6 PTHR46690:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005297.1|UniProtKB=W5MDC5 W5MDC5 PTHR42757:SF12 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED IGLON FAMILY MEMBER 5 cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;cell adhesion#GO:0007155;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000947.1|UniProtKB=W5LY53 W5LY53 PTHR24388:SF28 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 341 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000020993.1|UniProtKB=Q8HQM4 Q8HQM4 PTHR43507:SF20 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular respiration#GO:0045333;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007893.1|UniProtKB=W5MMH7 W5MMH7 PTHR46717:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF180 E3 UBIQUITIN-PROTEIN LIGASE RNF180 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;biological regulation#GO:0065007;biogenic amine metabolic process#GO:0006576;regulation of metabolic process#GO:0019222;amine metabolic process#GO:0009308;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;catecholamine metabolic process#GO:0006584;regulation of protein catabolic process#GO:0042176;serotonin metabolic process#GO:0042428;positive regulation of protein catabolic process#GO:0045732;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of proteasomal protein catabolic process#GO:1901800;indole-containing compound metabolic process#GO:0042430;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;phenol-containing compound metabolic process#GO:0018958;regulation of biological process#GO:0050789 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010985.1|UniProtKB=W5MYL6 W5MYL6 PTHR10970:SF2 CLUSTERIN CLUSTERIN-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005272.1|UniProtKB=W5MD96 W5MD96 PTHR13723:SF167 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 18 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000001988.1|UniProtKB=W5M1Q8 W5M1Q8 PTHR46071:SF3 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010928.1|UniProtKB=W5MYE2 W5MYE2 PTHR31489:SF2 LIN52 FAMILY MEMBER PROTEIN LIN-52 HOMOLOG LEPOC|Ensembl=ENSLOCG00000016932.1|UniProtKB=W5NJX4 W5NJX4 PTHR24064:SF457 SOLUTE CARRIER FAMILY 22 MEMBER TRANSPORTER SVOPL-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009904.1|UniProtKB=W5MUP9 W5MUP9 PTHR12011:SF469 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E1 ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003202.1|UniProtKB=W5M5X8 W5M5X8 PTHR31548:SF5 CLARIN CLARIN-2 LEPOC|Ensembl=ENSLOCG00000012622.1|UniProtKB=W5N4H8 W5N4H8 PTHR13415:SF2 NUCLEAR FACTOR-RELATED INTEGRATOR COMPLEX SUBUNIT 12 snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;integrator complex#GO:0032039;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012201.1|UniProtKB=W5N303 W5N303 PTHR45881:SF3 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED FORKHEAD BOX PROTEIN K2 LEPOC|Ensembl=ENSLOCG00000012215.1|UniProtKB=W5N317 W5N317 PTHR47980:SF16 LD44762P RAS-RELATED PROTEIN RAB-40B enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;export from cell#GO:0140352;catabolic process#GO:0009056;transport#GO:0006810;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;exocytosis#GO:0006887;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;vesicle-mediated transport#GO:0016192 plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 LEPOC|Ensembl=ENSLOCG00000005616.1|UniProtKB=W5MEG7 W5MEG7 PTHR24366:SF37 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT, IMMUNOGLOBULIN-LIKE AND TRANSMEMBRANE DOMAINS 1A immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005676.1|UniProtKB=W5MEP5 W5MEP5 PTHR31807:SF37 AUGMIN FAMILY MEMBER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 8 LEPOC|Ensembl=ENSLOCG00000010844.1|UniProtKB=W5MY35 W5MY35 PTHR10663:SF337 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 3 cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;cell projection membrane#GO:0031253;ruffle#GO:0001726 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000014724.1|UniProtKB=W5NBX1 W5NBX1 PTHR12027:SF34 WNT RELATED PROTEIN WNT signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677 regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;system development#GO:0048731;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 LEPOC|Ensembl=ENSLOCG00000008361.1|UniProtKB=W5MP44 W5MP44 PTHR31635:SF196 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000002589.1|UniProtKB=W5M3T3 W5M3T3 PTHR46902:SF1 DOMON DOMAIN-CONTAINING PROTEIN FRRS1L DOMON DOMAIN-CONTAINING PROTEIN FRRS1L regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072 LEPOC|Ensembl=ENSLOCG00000017472.1|UniProtKB=W5NLR8 W5NLR8 PTHR22750:SF25 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 12-LIKE G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009636.1|UniProtKB=W5MTR8 W5MTR8 PTHR11207:SF5 RIBONUCLEASE III LARGE RIBOSOMAL SUBUNIT PROTEIN ML44 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;translation#GO:0006412;RNA biosynthetic process#GO:0032774;mitochondrial translation#GO:0032543;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;negative regulation of metabolic process#GO:0009892;protein biosynthetic process#GO:0160307;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;primary miRNA processing#GO:0031053;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;translational elongation#GO:0006414;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 RNA metabolism protein#PC00031;endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000017770.1|UniProtKB=W5NML5 W5NML5 PTHR24233:SF1 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 34-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002131.1|UniProtKB=W5M270 W5M270 PTHR24103:SF700 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM7 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012033.1|UniProtKB=W5N2E2 W5N2E2 PTHR24133:SF51 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT AND SOCS BOX CONTAINING 4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004953.1|UniProtKB=W5MC46 W5MC46 PTHR24058:SF121 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transcription coactivator activity#GO:0003713;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;transcription regulator activity#GO:0140110;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004054.1|UniProtKB=W5M8Y8 W5M8Y8 PTHR11834:SF4 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;hippo signaling#GO:0035329;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000002098.1|UniProtKB=W5M221 W5M221 PTHR16719:SF0 CYTOCHROME C OXIDASE COPPER CHAPERONE CYTOCHROME C OXIDASE COPPER CHAPERONE molecular carrier activity#GO:0140104 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003428.1|UniProtKB=W5M6Q1 W5M6Q1 PTHR48620:SF1 TAX1-BINDING PROTEIN 3 TAX1-BINDING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000014984.1|UniProtKB=W5NCT9 W5NCT9 PTHR13817:SF186 TITIN FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010969.1|UniProtKB=W5MYM4 W5MYM4 PTHR19981:SF7 TALIN TALIN-1 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 organelle organization#GO:0006996;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cell adhesion#GO:0007155;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 Integrin signalling pathway#P00034>Talin#P00943 LEPOC|Ensembl=ENSLOCG00000016484.1|UniProtKB=W5NIA4 W5NIA4 PTHR35083:SF3 RGD1565685 PROTEIN SI:CH211-91P5.3 LEPOC|Ensembl=ENSLOCG00000010769.1|UniProtKB=W5MXU9 W5MXU9 PTHR13697:SF5 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, PLATELET TYPE phosphotransferase activity, alcohol group as acceptor#GO:0016773;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;carbohydrate derivative binding#GO:0097367;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;ADP catabolic process#GO:0046032 membrane#GO:0016020;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622 transferase#PC00220;carbohydrate kinase#PC00065;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000012529.1|UniProtKB=W5N481 W5N481 PTHR13389:SF0 PUMILIO HOMOLOG 3 PUMILIO HOMOLOG 3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000002724.1|UniProtKB=W5M491 W5M491 PTHR16684:SF11 CENTROMERE PROTEIN C CENTROMERE PROTEIN C binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565 cellular component assembly#GO:0022607;chromosome localization#GO:0050000;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;attachment of spindle microtubules to kinetochore#GO:0008608;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;localization#GO:0051179;kinetochore organization#GO:0051383;organelle fission#GO:0048285;organelle assembly#GO:0070925;organelle localization#GO:0051640;nuclear division#GO:0000280;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;kinetochore assembly#GO:0051382 kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228 centromere DNA-binding protein#PC00071 LEPOC|Ensembl=ENSLOCG00000006305.1|UniProtKB=W5MGV5 W5MGV5 PTHR13271:SF34 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE N-LYSINE METHYLTRANSFERASE SETD6 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 transferase#PC00220;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000003151.1|UniProtKB=W5M5R4 W5M5R4 PTHR11347:SF29 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010159.1|UniProtKB=W5MVN7 W5MVN7 DHX29 PTHR18934:SF264 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX29 catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013680.1|UniProtKB=W5N8B1 W5N8B1 PTHR46102:SF1 AXIN AXIN-2 ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389;beta-catenin binding#GO:0008013;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488 negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;positive regulation of catabolic process#GO:0009896;cellular developmental process#GO:0048869;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;anatomical structure development#GO:0048856;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cell cycle process#GO:0010564;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;positive regulation of proteasomal protein catabolic process#GO:1901800;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;regulation of Wnt signaling pathway#GO:0030111;cell development#GO:0048468 intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Axin#P01429 LEPOC|Ensembl=ENSLOCG00000015730.1|UniProtKB=W5NFF4 W5NFF4 PTHR11849:SF172 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 Interleukin signaling pathway#P00036>ELK#P00962 LEPOC|Ensembl=ENSLOCG00000015116.1|UniProtKB=W5ND93 W5ND93 PTHR10984:SF30 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 2 cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013292.1|UniProtKB=W5N6W2 W5N6W2 PTHR10558:SF2 SOMATOSTATIN SOMATOSTATIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000014595.1|UniProtKB=W5NBF1 W5NBF1 PTHR12817:SF7 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;Golgi apparatus#GO:0005794;cis-Golgi network#GO:0005801;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000013635.1|UniProtKB=W5N854 W5N854 PTHR12107:SF4 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-5 SUBUNIT calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;cell communication#GO:0007154;localization#GO:0051179;regulation of synaptic transmission, glutamatergic#GO:0051966;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;localization within membrane#GO:0051668;regulation of signaling#GO:0023051;nervous system process#GO:0050877;positive regulation of synaptic transmission#GO:0050806;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;transmission of nerve impulse#GO:0019226;system process#GO:0003008;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cell junction#GO:0030054;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241;ion channel#PC00133;transporter#PC00227 Ionotropic glutamate receptor pathway#P00037>stargazin#P00998 LEPOC|Ensembl=ENSLOCG00000001577.1|UniProtKB=W5M0A1 W5M0A1 PTHR46198:SF1 PROTEIN-TYROSINE-PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 5 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;phosphoprotein phosphatase activity#GO:0004721;protein binding#GO:0005515;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001736.1|UniProtKB=W5M0U8 W5M0U8 PTHR11984:SF39 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000005749.1|UniProtKB=W5MF02 W5MF02 PTHR12207:SF22 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 8 membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000016755.1|UniProtKB=W5NJ98 W5NJ98 PTHR24418:SF181 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BLK catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;B cell activation#P00010>Blk#P00390 LEPOC|Ensembl=ENSLOCG00000011517.1|UniProtKB=W5N0J0 W5N0J0 PTHR12599:SF13 PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytosol#GO:0005829;nucleus#GO:0005634 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000013605.1|UniProtKB=W5N814 W5N814 PTHR10985:SF165 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED DNA-BINDING PROTEIN DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of neurogenesis#GO:0050767;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;anterior/posterior pattern specification#GO:0009952;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000003481.1|UniProtKB=W5M6W8 W5M6W8 PTHR28620:SF1 CENTROMERE PROTEIN V CENTROMERE PROTEIN V LEPOC|Ensembl=ENSLOCG00000011846.1|UniProtKB=W5N1R4 W5N1R4 PTHR46618:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 3 ARMADILLO REPEAT-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000015965.1|UniProtKB=W5NGA1 W5NGA1 PTHR46428:SF1 KELCH DOMAIN-CONTAINING PROTEIN 10 KELCH DOMAIN-CONTAINING PROTEIN 10 positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of cellular response to stress#GO:0080135;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;positive regulation of MAPK cascade#GO:0043410 LEPOC|Ensembl=ENSLOCG00000018271.1|UniProtKB=W5NP13 W5NP13 PTHR11984:SF118 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of biological process#GO:0050789;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;anchoring junction#GO:0070161 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000013566.1|UniProtKB=W5N7W3 W5N7W3 PTHR24215:SF31 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE-RICH PROTEIN 1 cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000010030.1|UniProtKB=W5MV54 W5MV54 PTHR24023:SF1144 COLLAGEN ALPHA COLLAGEN TYPE XXV ALPHA 1 CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000016655.1|UniProtKB=W5NIW6 W5NIW6 PTHR21208:SF1 ADP-DEPENDENT GLUCOKINASE ADP-DEPENDENT GLUCOKINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;glucose metabolic process#GO:0006006;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000001291.1|UniProtKB=W5LZA8 W5LZA8 PTHR24393:SF151 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 956 transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008878.1|UniProtKB=W5MR00 W5MR00 PTHR11953:SF0 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP41 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA catabolic process#GO:0006401;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000007311.1|UniProtKB=W5MKF0 W5MKF0 PTHR13121:SF0 GPI TRANSAMIDASE COMPONENT PIG-U GPI-ANCHOR TRANSAMIDASE COMPONENT PIGU metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;GPI anchored protein biosynthesis#GO:0180046;biosynthetic process#GO:0009058 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;peptidase complex#GO:1905368;caspase complex#GO:0008303;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 LEPOC|Ensembl=ENSLOCG00000000709.1|UniProtKB=W5LXD0 W5LXD0 PTHR46664:SF1 ATM INTERACTOR ATM INTERACTOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000017337.1|UniProtKB=W5NLD3 W5NLD3 PTHR15895:SF14 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 5-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000016969.1|UniProtKB=W5NK17 W5NK17 PTHR12103:SF38 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181;hydrolase#PC00121;nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000007338.1|UniProtKB=W5MKJ0 W5MKJ0 PTHR18945:SF929 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT PI monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;trans-synaptic signaling#GO:0099537 signaling receptor complex#GO:0043235;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synapse#GO:0045202 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000010951.1|UniProtKB=W5MYH8 W5MYH8 PTHR46127:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65 cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317 cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;motile cilium#GO:0031514;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013581.1|UniProtKB=W5N7Z0 W5N7Z0 PTHR23349:SF41 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HEART- AND NEURAL CREST DERIVATIVES-EXPRESSED PROTEIN 2 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;heart development#GO:0007507;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000007753.1|UniProtKB=W5MM08 W5MM08 PTHR46202:SF1 DNA EXCISION REPAIR PROTEIN ERCC-8 DNA EXCISION REPAIR PROTEIN ERCC-8 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;nucleotide-excision repair complex#GO:0000109;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002200.1|UniProtKB=W5M2F1 W5M2F1 PTHR47147:SF2 SYNCOILIN SYNCOILIN, INTERMEDIATE FILAMENT PROTEIN LEPOC|Ensembl=ENSLOCG00000018227.1|UniProtKB=W5NNW9 W5NNW9 PTHR19944:SF62 MHC CLASS II-RELATED BETA-2-MICROGLOBULIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823;protein-containing complex binding#GO:0044877 cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of leukocyte activation#GO:0002696;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;immune system process#GO:0002376;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of cellular process#GO:0048522;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;vesicle#GO:0031982;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome membrane#GO:0031902;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;membrane#GO:0016020;vesicle membrane#GO:0012506;lysosomal membrane#GO:0005765;cell periphery#GO:0071944 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000005191.1|UniProtKB=W5MCZ0 W5MCZ0 PTHR24418:SF265 TYROSINE-PROTEIN KINASE PROTEIN-TYROSINE KINASE 6 catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715 enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000003634.1|UniProtKB=W5M7F4 W5M7F4 PTHR12675:SF4 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000006308.1|UniProtKB=W5MGV4 W5MGV4 PTHR12448:SF0 ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT EPSILON, MITOCHONDRIAL monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252 oxidative phosphorylation#GO:0006119;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000006237.1|UniProtKB=W5MGM0 W5MGM0 PTHR31844:SF1 MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR-RELATED PROTEIN FAM168A positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;positive regulation of DNA metabolic process#GO:0051054;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893 structural protein#PC00211;myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000006187.1|UniProtKB=W5MGI5 W5MGI5 PTHR11206:SF515 MULTIDRUG RESISTANCE PROTEIN MULTIDRUG AND TOXIN EXTRUSION PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002789.1|UniProtKB=W5M4H2 W5M4H2 PTHR12952:SF0 SYS1 PROTEIN SYS1 HOMOLOG vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;protein localization to cell periphery#GO:1990778;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;protein localization to organelle#GO:0033365;Golgi to endosome transport#GO:0006895;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002663.1|UniProtKB=W5M422 W5M422 PTHR31396:SF2 PROTEIN FAM163B MEMBER PROTEIN FAM163B LEPOC|Ensembl=ENSLOCG00000005286.1|UniProtKB=W5MDB1 W5MDB1 PTHR24028:SF46 CADHERIN-87A PROTOCADHERIN-8 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000007416.1|UniProtKB=W5MKU1 W5MKU1 PTHR23105:SF31 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008822.1|UniProtKB=W5MQU2 W5MQU2 PTHR45742:SF5 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C8 BETA CHAIN humoral immune response#GO:0006959;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778;positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;immune response#GO:0006955;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896 extracellular region#GO:0005576;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000001786.1|UniProtKB=W5M116 W5M116 PTHR43053:SF6 GLYCOSIDASE FAMILY 31 GLYCOSYL HYDROLASE FAMILY 31 C-TERMINAL DOMAIN-CONTAINING PROTEIN hydrolase#PC00121;glucosidase#PC00108;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017902.1|UniProtKB=W5NMZ6 W5NMZ6 PTHR17575:SF1 UROCORTIN-2 AND 3 UROCORTIN-3 G protein-coupled receptor binding#GO:0001664;neuropeptide receptor binding#GO:0071855;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;response to nutrient levels#GO:0031667;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to nutrient levels#GO:0031669;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008505.1|UniProtKB=W5MPP2 W5MPP2 PTHR14453:SF94 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP10 transcription coregulator activity#GO:0003712;transferase activity#GO:0016740;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;negative regulation of biosynthetic process#GO:0009890;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004947.1|UniProtKB=W5MC39 W5MC39 PTHR17206:SF1 PROLACTIN-RELEASING PEPTIDE PROLACTIN-RELEASING PEPTIDE neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;neuropeptide hormone activity#GO:0005184;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;feeding behavior#GO:0007631 LEPOC|Ensembl=ENSLOCG00000003404.1|UniProtKB=W5M6M9 W5M6M9 PTHR22935:SF95 PENICILLIN-BINDING PROTEIN BETA-LACTAMASE-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000000951.1|UniProtKB=W5LY50 W5LY50 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006496.1|UniProtKB=W5MHJ4 W5MHJ4 PTHR42985:SF48 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 2 monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 sodium ion transport#GO:0006814;transport#GO:0006810;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015837.1|UniProtKB=W5NFU8 W5NFU8 PTHR15711:SF70 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE 2-RELATED enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000015556.1|UniProtKB=W5NEU5 W5NEU5 PTHR12363:SF42 TRANSPORTIN 3 AND IMPORTIN 13 TRANSPORTIN-3 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003529.1|UniProtKB=W5M712 W5M712 PTHR46349:SF8 CINGULIN-LIKE PROTEIN 1-RELATED MYOSIN TAIL DOMAIN-CONTAINING PROTEIN protein localization to cell junction#GO:1902414;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179 anchoring junction#GO:0070161;bicellular tight junction#GO:0005923;cell junction#GO:0030054;tight junction#GO:0070160;cellular anatomical structure#GO:0110165;apical junction complex#GO:0043296;cell-cell junction#GO:0005911 LEPOC|Ensembl=ENSLOCG00000004586.1|UniProtKB=W5MAT6 W5MAT6 PTHR24391:SF15 HISTONE H4 TRANSCRIPTION FACTOR-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000004106.1|UniProtKB=W5M975 W5M975 PTHR43807:SF14 FI04487P KYNURENINE--OXOGLUTARATE TRANSAMINASE 1 transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000008428.1|UniProtKB=W5MPE0 W5MPE0 PTHR45713:SF11 FTP DOMAIN-CONTAINING PROTEIN FUCOLECTIN LEPOC|Ensembl=ENSLOCG00000017973.1|UniProtKB=W5NN65 W5NN65 PTHR10489:SF635 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 7 cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515 response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;cell communication#GO:0007154;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;locomotion#GO:0040011 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000006087.1|UniProtKB=W5MG77 W5MG77 PTHR10480:SF1 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG A syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;calmodulin binding#GO:0005516;SNARE binding#GO:0000149 cellular localization#GO:0051641;secretion by cell#GO:0032940;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;signaling#GO:0023052;export from cell#GO:0140352;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;synaptic transmission, glutamatergic#GO:0035249;neurotransmitter transport#GO:0006836;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;calcium-ion regulated exocytosis#GO:0017156;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;vesicle localization#GO:0051648;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269 vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;neuron projection terminus#GO:0044306;intracellular membrane-bounded organelle#GO:0043231;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;axon#GO:0030424;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;axon terminus#GO:0043679;organelle membrane#GO:0031090;neuromuscular junction#GO:0031594;intracellular vesicle#GO:0097708;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;synaptic membrane#GO:0097060;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000007752.1|UniProtKB=W5MM03 W5MM03 PTHR16983:SF10 UPAR/LY6 DOMAIN-CONTAINING PROTEIN PROTEIN QUIVER protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017352.1|UniProtKB=W5NLE8 W5NLE8 PTHR20978:SF0 SPLICING FACTOR 3B SUBUNIT 5 SPLICING FACTOR 3B SUBUNIT 5 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010156.1|UniProtKB=W5MVM7 W5MVM7 PTHR12406:SF48 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 4 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;triacylglycerol lipase activity#GO:0004806;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycerolipid catabolic process#GO:0046503;triglyceride catabolic process#GO:0019433;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;homeostatic process#GO:0042592;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;neutral lipid metabolic process#GO:0006638;acylglycerol catabolic process#GO:0046464;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;triglyceride metabolic process#GO:0006641;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;cellular process#GO:0009987;lipid catabolic process#GO:0016042 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000011527.1|UniProtKB=W5N0K5 W5N0K5 PTHR19308:SF2 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN START DOMAIN-CONTAINING PROTEIN 10 LEPOC|Ensembl=ENSLOCG00000017067.1|UniProtKB=W5NKD1 W5NKD1 PTHR11589:SF4 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIN-3 growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;regulation of trans-synaptic signaling#GO:0099177;nervous system development#GO:0007399;negative regulation of neuron apoptotic process#GO:0043524;neuron projection development#GO:0031175;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;cellular response to nerve growth factor stimulus#GO:1990090;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182 exocytic vesicle#GO:0070382;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell junction#GO:0030054;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle#GO:0030133 neurotrophic factor#PC00163;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000011589.1|UniProtKB=W5N0T4 W5N0T4 PTHR13976:SF42 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED G-RICH SEQUENCE FACTOR 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000017086.1|UniProtKB=W5NKF6 W5NKF6 PTHR10026:SF7 CYCLIN CYCLIN-C cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000002675.1|UniProtKB=W5M430 W5M430 PTHR22750:SF22 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 1 bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental process#GO:0032502;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003340.1|UniProtKB=W5M6D9 W5M6D9 PTHR45915:SF7 TRANSCRIPTION INTERMEDIARY FACTOR TRIPARTITE MOTIF-CONTAINING PROTEIN 66 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;transcription regulator activity#GO:0140110;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;transferase activity#GO:0016740 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006296.1|UniProtKB=W5MGW6 W5MGW6 PTHR24202:SF4 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB2-RELATED acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003584.1|UniProtKB=W5M795 W5M795 PTHR21740:SF3 NCK-ASSOCIATED PROTEIN 5 NCK-ASSOCIATED PROTEIN 5-LIKE microtubule depolymerization#GO:0007019;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule bundle formation#GO:0001578 microtubule plus-end#GO:0035371;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752 LEPOC|Ensembl=ENSLOCG00000014830.1|UniProtKB=W5NCA3 W5NCA3 PTHR45589:SF2 WD REPEAT DOMAIN 62, ISOFORM G WD REPEAT-CONTAINING PROTEIN 62 ISOFORM X1 regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000014064.1|UniProtKB=W5N9N5 W5N9N5 PTHR15976:SF14 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PPAR-GAMMA-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000018319.1|UniProtKB=W5NP61 W5NP61 PTHR11984:SF12 CONNEXIN GAP JUNCTION ALPHA-3 PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cell communication#GO:0007154 anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000010550.1|UniProtKB=W5MX17 W5MX17 PTHR15337:SF1 ANTERIOR GRADIENT PROTEIN-RELATED ANTERIOR GRADIENT PROTEIN 2 HOMOLOG response to stress#GO:0006950;inflammatory response#GO:0006954;response to stimulus#GO:0050896;defense response#GO:0006952 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000012586.1|UniProtKB=W5N4D6 W5N4D6 PTHR28630:SF35 FAMILY NOT NAMED PEROXIREDOXIN-LIKE 2A intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015651.1|UniProtKB=W5NF56 W5NF56 PTHR11787:SF1 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR BETA enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013282.1|UniProtKB=W5N6V4 W5N6V4 PTHR12735:SF27 BOLA-LIKE PROTEIN-RELATED BOLA-LIKE PROTEIN 2 iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094 intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000007769.1|UniProtKB=W5MM26 W5MM26 PTHR32470:SF2 ADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2 mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000006264.1|UniProtKB=W5MGR1 W5MGR1 PTHR14234:SF18 RIM BINDING PROTEIN-RELATED RIMS-BINDING PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049 synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;cytoplasm#GO:0005737;cell cortex#GO:0005938;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017223.1|UniProtKB=W5NKZ1 W5NKZ1 PTHR13439:SF7 CT120 PROTEIN PROTEIN CLN8 lipid binding#GO:0008289;binding#GO:0005488 system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;phospholipid metabolic process#GO:0006644;homeostatic process#GO:0042592;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;phosphorus metabolic process#GO:0006793;multicellular organism development#GO:0007275;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;developmental process#GO:0032502;metabolic process#GO:0008152;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003959.1|UniProtKB=W5M8M1 W5M8M1 PTHR19282:SF3 TETRASPANIN TETRASPANIN-31 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009276.1|UniProtKB=W5MSF5 W5MSF5 PTHR11848:SF117 TGF-BETA FAMILY INHIBIN ALPHA CHAIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inha#P06855 LEPOC|Ensembl=ENSLOCG00000016464.1|UniProtKB=W5NI79 W5NI79 PTHR24070:SF373 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 PDGF signaling pathway#P00047>Ras#P01154 LEPOC|Ensembl=ENSLOCG00000001564.1|UniProtKB=W5M0C9 W5M0C9 PTHR22988:SF71 MYOTONIC DYSTROPHY S/T KINASE-RELATED CITRON RHO-INTERACTING KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 actomyosin structure organization#GO:0031032;regulation of cellular component organization#GO:0051128;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;cell cycle#GO:0007049;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;actin filament-based process#GO:0030029;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000004239.1|UniProtKB=W5M9K9 W5M9K9 PTHR45829:SF2 MITOCHONDRIAL CARRIER PROTEIN RIM2 SOLUTE CARRIER FAMILY 25 MEMBER 36 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000006759.1|UniProtKB=W5MIF8 W5MIF8 PTHR13318:SF193 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 16 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000006442.1|UniProtKB=W5MHC0 W5MHC0 PTHR18952:SF84 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 14 catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000009858.1|UniProtKB=W5MUJ4 W5MUJ4 PTHR22957:SF686 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN GROWTH HORMONE-REGULATED TBC PROTEIN 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000001628.1|UniProtKB=W5M0H8 W5M0H8 PTHR28633:SF2 HERMANSKY-PUDLAK SYNDROME 3 PROTEIN HPS3 BIOGENESIS OF LYSOSOMAL ORGANELLES COMPLEX 2 SUBUNIT 1 LEPOC|Ensembl=ENSLOCG00000009622.1|UniProtKB=W5MTQ5 W5MTQ5 PTHR16501:SF17 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 11 MITOCHONDRIAL FISSION FACTOR regulation of anatomical structure morphogenesis#GO:0022603;intracellular protein localization#GO:0008104;positive regulation of developmental process#GO:0051094;biological regulation#GO:0065007;macromolecule localization#GO:0033036;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of organelle organization#GO:0010638;localization#GO:0051179;positive regulation of cellular component organization#GO:0051130;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;positive regulation of mitochondrial fission#GO:0090141;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;protein localization to mitochondrion#GO:0070585;regulation of organelle organization#GO:0033043;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789 mitochondrial envelope#GO:0005740;microbody#GO:0042579;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;organelle envelope#GO:0031967;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000016782.1|UniProtKB=W5NJD6 W5NJD6 PTHR12400:SF26 INOSITOL POLYPHOSPHATE KINASE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000003619.1|UniProtKB=W5M7G0 W5M7G0 PTHR24390:SF272 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 76 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000005135.1|UniProtKB=W5MCS3 W5MCS3 PTHR12129:SF17 HEPARAN SULFATE 2-O-SULFOTRANSFERASE HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000585.1|UniProtKB=W5LWZ0 W5LWZ0 PTHR11846:SF13 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ligase#PC00142;metabolite interconversion enzyme#PC00262 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 LEPOC|Ensembl=ENSLOCG00000009071.1|UniProtKB=W5MRP2 W5MRP2 PTHR22948:SF29 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 5 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008135.1|UniProtKB=W5MNB5 W5MNB5 PTHR16119:SF17 TRANSMEMBRANE PROTEIN 144 TRANSMEMBRANE PROTEIN 144 LEPOC|Ensembl=ENSLOCG00000017583.1|UniProtKB=W5NM29 W5NM29 PTHR12307:SF55 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT ATM INTERACTOR phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247;binding#GO:0005488;enzyme binding#GO:0019899;carbohydrate binding#GO:0030246;protein binding#GO:0005515;protein phosphatase binding#GO:0019903 regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;biological regulation#GO:0065007;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of polysaccharide metabolic process#GO:0032881;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000013290.1|UniProtKB=W5N6W5 W5N6W5 PTHR13720:SF14 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 52 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005705.1|UniProtKB=W5MEV2 W5MEV2 PTHR11347:SF98 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8B hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of response to stimulus#GO:0048585;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000014549.1|UniProtKB=W5NB99 W5NB99 PTHR13604:SF1 DC12-RELATED ABASIC SITE PROCESSING PROTEIN HMCES lyase activity#GO:0016829;DNA binding#GO:0003677;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824 response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;multicellular organismal process#GO:0032501;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;interstrand cross-link repair#GO:0036297;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;developmental process#GO:0032502;double-strand break repair via nonhomologous end joining#GO:0006303;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;production of molecular mediator of immune response#GO:0002440;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;cellular response to stress#GO:0033554;anatomical structure development#GO:0048856;immune system development#GO:0002520;system development#GO:0048731 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002429.1|UniProtKB=W5M3A7 W5M3A7 PTHR10372:SF5 PLAKOPHILLIN-RELATED SPLICING REGULATOR ARVCF cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;nucleus#GO:0005634;cell-cell junction#GO:0005911;membrane#GO:0016020 intermediate filament binding protein#PC00130;intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010458.1|UniProtKB=W5MWT5 W5MWT5 PTHR11920:SF509 GUANYLYL CYCLASE ATRIAL NATRIURETIC PEPTIDE RECEPTOR 2 molecular transducer activity#GO:0060089;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653 cell communication#GO:0007154;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cyclic nucleotide biosynthetic process#GO:0009190;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 lyase#PC00144;guanylate cyclase#PC00114 Gonadotropin-releasing hormone receptor pathway#P06664>Npr2#P06796 LEPOC|Ensembl=ENSLOCG00000011244.1|UniProtKB=W5MZL9 W5MZL9 PTHR10766:SF41 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3 intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;localization within membrane#GO:0051668;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000715.1|UniProtKB=W5LXE4 W5LXE4 PTHR15092:SF44 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 POLY(A)-SPECIFIC RIBONUCLEASE PARN RNA binding#GO:0003723;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;RNA 3'-end processing#GO:0031123;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA processing#GO:0006396;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000004233.1|UniProtKB=W5M9K4 W5M9K4 PTHR15623:SF11 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2-RELATED SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007257.1|UniProtKB=W5MK72 W5MK72 PTHR45781:SF3 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 3 DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000011044.1|UniProtKB=W5MYU7 W5MYU7 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to other organism#GO:0051707 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011773.1|UniProtKB=W5N1G9 W5N1G9 PTHR12504:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;protein transport#GO:0015031;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000016256.1|UniProtKB=W5NHD7 W5NHD7 PTHR34524:SF3 CALCYPHOSIN CALCYPHOSIN-2 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000005499.1|UniProtKB=W5ME33 W5ME33 PTHR11567:SF215 ACID PHOSPHATASE-RELATED LYSOSOMAL ACID PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;acid phosphatase activity#GO:0003993;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;lysosome#GO:0005764;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000016750.1|UniProtKB=W5NJ99 W5NJ99 PTHR18905:SF12 NINEIN NINEIN-LIKE PROTEIN microtubule-based process#GO:0007017;microtubule anchoring#GO:0034453;microtubule cytoskeleton organization#GO:0000226;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 PDGF signaling pathway#P00047>GSK3#P01153 LEPOC|Ensembl=ENSLOCG00000000142.1|UniProtKB=W5LVJ9 W5LVJ9 PTHR45786:SF74 DNA BINDING PROTEIN-LIKE ATP-DEPENDENT DNA HELICASE LEPOC|Ensembl=ENSLOCG00000017995.1|UniProtKB=W5NN87 W5NN87 PTHR19957:SF30 SYNTAXIN SYNTAXIN-11 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;exocytosis#GO:0006887;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;export from cell#GO:0140352;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;secretion by cell#GO:0032940 intracellular anatomical structure#GO:0005622;SNARE complex#GO:0031201;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000009412.1|UniProtKB=W5MSX9 W5MSX9 PTHR23086:SF34 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 BETA catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 kinase#PC00137;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000014184.1|UniProtKB=W5NA13 W5NA13 PTHR43157:SF32 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 12 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000008113.1|UniProtKB=W5MNC0 W5MNC0 PTHR24270:SF66 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transfer/carrier protein#PC00219;apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000003532.1|UniProtKB=W5M722 W5M722 PTHR11949:SF24 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 9 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000016640.1|UniProtKB=W5NIU9 W5NIU9 PTHR21236:SF7 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF4 Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043;vesicle fusion#GO:0006906 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus subcompartment#GO:0098791 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014657.1|UniProtKB=W5NBN5 W5NBN5 PTHR47091:SF1 ALPHA-PROTEIN KINASE 2-RELATED ALPHA-PROTEIN KINASE 3 muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;cell development#GO:0048468;muscle structure development#GO:0061061;circulatory system development#GO:0072359;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;cellular process#GO:0009987;cardiac muscle cell differentiation#GO:0055007;tissue development#GO:0009888;multicellular organismal process#GO:0032501;heart development#GO:0007507;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;striated muscle cell differentiation#GO:0051146;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005564.1|UniProtKB=W5MEB2 W5MEB2 PTHR46160:SF9 ALPHA-TECTORIN-RELATED DENDRITE EXTENSION DEFECTIVE PROTEIN 1-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000006828.1|UniProtKB=W5MIP8 W5MIP8 PTHR16461:SF5 TOLL-INTERACTING PROTEIN TOLL-INTERACTING PROTEIN binding#GO:0005488;enzyme binding#GO:0019899;ubiquitin binding#GO:0043130;protein binding#GO:0005515 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Toll receptor signaling pathway#P00054>Tollip#P01379 LEPOC|Ensembl=ENSLOCG00000015740.1|UniProtKB=W5NFH2 W5NFH2 PTHR11878:SF6 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER 1 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;regulation of system process#GO:0044057;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of heart contraction#GO:0008016;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;chemical homeostasis#GO:0048878;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;export from cell#GO:0140352;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789 postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;axon#GO:0030424;cell junction#GO:0030054;sarcolemma#GO:0042383 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000000106.1|UniProtKB=W5LVF8 W5LVF8 PTHR48034:SF5 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED COLD-INDUCIBLE RNA-BINDING PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009475.1|UniProtKB=W5MT55 W5MT55 PTHR46608:SF3 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 ion binding#GO:0043167;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;binding#GO:0005488;anion binding#GO:0043168;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 phagocytosis#GO:0006909;transport#GO:0006810;apoptotic cell clearance#GO:0043277;localization#GO:0051179;endocytosis#GO:0006897;establishment of localization#GO:0051234;import into cell#GO:0098657 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002857.1|UniProtKB=W5M4R9 W5M4R9 PTHR21389:SF0 P53 INDUCED PROTEIN ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG catabolic process#GO:0009056;macroautophagy#GO:0016236;process utilizing autophagic mechanism#GO:0061919;metabolic process#GO:0008152;autophagy#GO:0006914;cellular process#GO:0009987 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000007778.1|UniProtKB=W5MM35 W5MM35 PTHR22526:SF2 ANAPHASE PROMOTING COMPLEX C SUBUNIT 15, PSEUDOGENE-RELATED ANAPHASE PROMOTING COMPLEX C SUBUNIT 15, PSEUDOGENE-RELATED regulation of response to stimulus#GO:0048583;regulation of chromosome segregation#GO:0051983;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic cell cycle#GO:0007346;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of cell communication#GO:0010646;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular component organization#GO:0051128 nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013215.1|UniProtKB=W5N6L9 W5N6L9 PTHR21472:SF19 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ZGC:172339 LEPOC|Ensembl=ENSLOCG00000006895.1|UniProtKB=W5MIX9 W5MIX9 PTHR24409:SF441 ZINC FINGER PROTEIN 142 TRANSCRIPTIONAL REPRESSOR CTCF transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000010004.1|UniProtKB=W5MV23 W5MV23 PTHR24070:SF264 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RHEB kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;protein kinase activator activity#GO:0030295;hydrolase activity#GO:0016787;kinase activator activity#GO:0019209;GTPase activity#GO:0003924 positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of TOR signaling#GO:0032008;positive regulation of TORC1 signaling#GO:1904263;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of response to stimulus#GO:0048584;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of TORC1 signaling#GO:1903432 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 CCKR signaling map#P06959>RHEB-GTP#P07224;CCKR signaling map#P06959>RHEB-GDP#P07175;p53 pathway by glucose deprivation#P04397>Rheb#P04642 LEPOC|Ensembl=ENSLOCG00000006269.1|UniProtKB=W5MGR4 W5MGR4 PTHR31037:SF2 RELT-LIKE PROTEIN 1-RELATED RELT TNF RECEPTOR positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015285.1|UniProtKB=W5NDU6 W5NDU6 PTHR24068:SF141 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 N catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein K63-linked ubiquitination#GO:0070534;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Toll receptor signaling pathway#P00054>Ubc13#P01381 LEPOC|Ensembl=ENSLOCG00000011652.1|UniProtKB=W5N125 W5N125 PTHR14604:SF5 WD40 REPEAT PF20 F-BOX_WD REPEAT-CONTAINING PROTEIN 1A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 transferase complex#GO:1990234;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 microtubule or microtubule-binding cytoskeletal protein#PC00157 Wnt signaling pathway#P00057>betaTrCP#P01454;Hedgehog signaling pathway#P00025>Slimb#P00683 LEPOC|Ensembl=ENSLOCG00000012960.1|UniProtKB=W5N5Q6 W5N5Q6 PTHR11461:SF399 SERINE PROTEASE INHIBITOR, SERPIN LEUKOCYTE ELASTASE INHIBITOR-RELATED endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000014649.1|UniProtKB=W5NBM3 W5NBM3 PTHR23179:SF36 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED RHO-GAP DOMAIN-CONTAINING PROTEIN enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000002237.1|UniProtKB=W5M2J4 W5M2J4 PTHR13738:SF15 TROPONIN I TROPONIN I, FAST SKELETAL MUSCLE protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 neuromuscular process#GO:0050905;cardiac muscle contraction#GO:0060048;muscle contraction#GO:0006936;nervous system process#GO:0050877;circulatory system process#GO:0003013;heart contraction#GO:0060047;system process#GO:0003008;muscle system process#GO:0003012;heart process#GO:0003015;striated muscle contraction#GO:0006941;skeletal muscle contraction#GO:0003009;blood circulation#GO:0008015;multicellular organismal process#GO:0032501 supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000008840.1|UniProtKB=W5MQV1 W5MQV1 PTHR15706:SF10 SH3 MULTIPLE DOMAIN NADPH OXIDASE ORGANIZER 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;superoxide metabolic process#GO:0006801 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008972.1|UniProtKB=W5MRB9 W5MRB9 PTHR20923:SF1 BAT4 PROTEIN-RELATED G PATCH DOMAIN AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000014715.1|UniProtKB=W5NBV4 W5NBV4 PTHR15151:SF26 PROTEIN EIGER ECTODYSPLASIN-A molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016052.1|UniProtKB=W5NGL6 W5NGL6 PTHR12358:SF25 SPHINGOSINE KINASE CERAMIDE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid kinase activity#GO:0001727 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987;ceramide metabolic process#GO:0006672 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016279.1|UniProtKB=W5NHH3 W5NHH3 PTHR12081:SF25 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F7 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000015634.1|UniProtKB=W5NF38 W5NF38 PTHR21588:SF18 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6 MICOS COMPLEX SUBUNIT MIC19 membrane organization#GO:0061024;mitochondrion organization#GO:0007005;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000015309.1|UniProtKB=W5NDX7 W5NDX7 PTHR13163:SF0 SPINAL CORD EXPRESSION PROTEIN 4 NOVEL ACETYLCHOLINE RECEPTOR CHAPERONE signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548;neurotransmitter receptor regulator activity#GO:0099602;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;positive regulation of biological process#GO:0048518;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;biological regulation#GO:0065007;cellular component assembly#GO:0022607;chaperone-mediated protein complex assembly#GO:0051131;protein-containing complex organization#GO:0043933;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000000435.1|UniProtKB=W5LWH0 W5LWH0 PTHR12213:SF0 CORRINOID ADENOSYLTRANSFERASE CORRINOID ADENOSYLTRANSFERASE MMAB transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000009624.1|UniProtKB=W5MTQ6 W5MTQ6 PTHR11699:SF140 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE 1A1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 regulation of hormone levels#GO:0010817;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;isoprenoid biosynthetic process#GO:0008299;terpenoid metabolic process#GO:0006721;oxoacid metabolic process#GO:0043436;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;aldehyde catabolic process#GO:0046185;biosynthetic process#GO:0009058;biological regulation#GO:0065007;terpenoid biosynthetic process#GO:0016114;lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;diterpenoid biosynthetic process#GO:0016102;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;monocarboxylic acid biosynthetic process#GO:0072330;retinoid metabolic process#GO:0001523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000005951.1|UniProtKB=W5MFM9 W5MFM9 PTHR31516:SF18 STABILIZER OF AXONEMAL MICROTUBULES 2 TRANSLATION INITIATION FACTOR IF-2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000001022.1|UniProtKB=W5LYD9 W5LYD9 PTHR10404:SF32 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE INACTIVE N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE-LIKE PROTEIN 2 peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000002796.1|UniProtKB=W5M4I2 W5M4I2 PTHR24414:SF27 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 10 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;DNA binding#GO:0003677 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000008066.1|UniProtKB=W5MN51 W5MN51 PTHR24020:SF49 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXVIII) CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000009900.1|UniProtKB=W5MUP0 W5MUP0 PTHR12893:SF2 GOLGI REASSEMBLY STACKING PROTEIN GRASP GOLGI REASSEMBLY-STACKING PROTEIN 1 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000009212.1|UniProtKB=W5MS76 W5MS76 PTHR11871:SF1 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B BETA ISOFORM enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cytosol#GO:0005829 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629 LEPOC|Ensembl=ENSLOCG00000009564.1|UniProtKB=W5MTI5 W5MTI5 PTHR10288:SF93 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of catabolic process#GO:0009895;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;mRNA stabilization#GO:0048255;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005446.1|UniProtKB=W5MDW6 W5MDW6 PTHR45616:SF59 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 8 structural molecule activity#GO:0005198 cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;skin development#GO:0043588;epithelium development#GO:0060429;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular developmental process#GO:0048869;developmental process#GO:0032502;epidermis development#GO:0008544 organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016988.1|UniProtKB=W5NK39 W5NK39 PTHR34257:SF4 ADAPTER PROTEIN CIKS E3 UBIQUITIN LIGASE TRAF3IP2 regulation of signaling#GO:0023051;immune system process#GO:0002376;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;humoral immune response#GO:0006959;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006409.1|UniProtKB=W5MH88 W5MH88 PTHR10131:SF96 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 1 signaling adaptor activity#GO:0035591;protein binding#GO:0005515;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;tumor necrosis factor receptor superfamily binding#GO:0032813;molecular adaptor activity#GO:0060090 regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;response to tumor necrosis factor#GO:0034612;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;cytokine-mediated signaling pathway#GO:0019221;regulation of signaling#GO:0023051;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;response to peptide#GO:1901652;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000413.1|UniProtKB=W5LWE7 W5LWE7 PTHR23235:SF50 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000005776.1|UniProtKB=W5MF12 W5MF12 PTHR11732:SF294 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000001116.1|UniProtKB=W5LYQ2 W5LYQ2 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003591.1|UniProtKB=W5M797 W5M797 PTHR15268:SF17 THRAP3/BCLAF1 BCLAF1 AND THRAP3 FAMILY MEMBER 3 transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA binding#GO:0003677 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008097.1|UniProtKB=W5MN78 W5MN78 PTHR45936:SF1 TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010902.1|UniProtKB=W5MYB6 W5MYB6 PTHR23036:SF96 CYTOKINE RECEPTOR INTERLEUKIN-31 RECEPTOR SUBUNIT ALPHA molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 cytokine-mediated signaling pathway#GO:0019221;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002204.1|UniProtKB=W5M2F6 W5M2F6 PTHR35451:SF2 NEUROPEPTIDE-LIKE PROTEIN C4ORF48 NELL2-INTERACTING CELL ONTOGENY REGULATOR 1 LEPOC|Ensembl=ENSLOCG00000006824.1|UniProtKB=W5MIN5 W5MIN5 PTHR32001:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 2 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT KCP2 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 LEPOC|Ensembl=ENSLOCG00000005103.1|UniProtKB=W5MCN7 W5MCN7 PTHR22776:SF107 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CHEMOKINE-LIKE FACTOR signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response#GO:0006955;immune system process#GO:0002376 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016218.1|UniProtKB=W5NH90 W5NH90 PTHR45614:SF5 MYB PROTEIN-RELATED TRANSCRIPTIONAL ACTIVATOR MYB sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;cell cycle#GO:0007049;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006292.1|UniProtKB=W5MGU1 W5MGU1 PTHR11588:SF112 TUBULIN TUBULIN BETA-1 CHAIN heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl nucleotide binding#GO:0019001;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 LEPOC|Ensembl=ENSLOCG00000012569.1|UniProtKB=W5N4B5 W5N4B5 PTHR34339:SF1 STIMULATOR OF INTERFERON GENES PROTEIN STIMULATOR OF INTERFERON GENES PROTEIN guanyl ribonucleotide binding#GO:0032561;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553 positive regulation of metabolic process#GO:0009893;biological process involved in interspecies interaction between organisms#GO:0044419;positive regulation of macroautophagy#GO:0016239;defense response to virus#GO:0051607;cellular component organization#GO:0016043;positive regulation of response to external stimulus#GO:0032103;regulation of macroautophagy#GO:0016241;metabolic process#GO:0008152;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;autophagy#GO:0006914;positive regulation of biosynthetic process#GO:0009891;vacuole organization#GO:0007033;organelle assembly#GO:0070925;catabolic process#GO:0009056;positive regulation of cytokine production#GO:0001819;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;positive regulation of gene expression#GO:0010628;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;macroautophagy#GO:0016236;response to other organism#GO:0051707;activation of innate immune response#GO:0002218;regulation of macromolecule biosynthetic process#GO:0010556;reticulophagy#GO:0061709;positive regulation of innate immune response#GO:0045089;positive regulation of macromolecule biosynthetic process#GO:0010557;process utilizing autophagic mechanism#GO:0061919;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;cellular component biogenesis#GO:0044085;response to biotic stimulus#GO:0009607;organelle organization#GO:0006996;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;autophagosome organization#GO:1905037;cellular process#GO:0009987;response to virus#GO:0009615;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of type I interferon production#GO:0032481;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;regulation of catabolic process#GO:0009894;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;immune response#GO:0006955 vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;autophagosome#GO:0005776 LEPOC|Ensembl=ENSLOCG00000018194.1|UniProtKB=W5NNT6 W5NNT6 PTHR28649:SF5 PROTEIN REPRIMO-RELATED REPRIMO, TP53-DEPENDENT G2 ARREST MEDIATOR HOMOLOG 3 LEPOC|Ensembl=ENSLOCG00000010332.1|UniProtKB=W5MW99 W5MW99 PTHR43503:SF4 MCG48959-RELATED PEROXIREDOXIN-6 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015090.1|UniProtKB=W5ND62 W5ND62 PTHR22227:SF6 FAMILY WITH SEQUENCE SIMILARITY 122B ISOFORM X1 PROTEIN FAM122B ISOFORM X1 enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;protein serine/threonine phosphatase inhibitor activity#GO:0004865;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of protein metabolic process#GO:0051247;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of ubiquitin-dependent protein catabolic process#GO:2000058 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013384.1|UniProtKB=W5N789 W5N789 PTHR15343:SF0 CD7 T-CELL ANTIGEN CD7 LEPOC|Ensembl=ENSLOCG00000002518.1|UniProtKB=W5M3K6 W5M3K6 PTHR24418:SF39 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE LCK non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;lymphocyte activation#GO:0046649;T cell differentiation#GO:0030217;positive regulation of immune system process#GO:0002684;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;immune system process#GO:0002376;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;mononuclear cell differentiation#GO:1903131;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of immune response#GO:0050778;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;hemopoiesis#GO:0030097;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 T cell activation#P00053>Lck#P01310;Parkinson disease#P00049>Src kinase#P01230 LEPOC|Ensembl=ENSLOCG00000003409.1|UniProtKB=W5M6Q5 W5M6Q5 PTHR23220:SF79 INTEGRIN ALPHA INTEGRIN ALPHA-E signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell surface receptor signaling pathway#GO:0007166 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000007359.1|UniProtKB=W5MKL7 W5MKL7 PTHR15977:SF15 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 46 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 46 LEPOC|Ensembl=ENSLOCG00000007931.1|UniProtKB=W5MMM6 W5MMM6 PTHR11699:SF308 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE (NAD(+)) oxidoreductase activity#GO:0016491;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 aldehyde catabolic process#GO:0046185;catabolic process#GO:0009056;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000015359.1|UniProtKB=W5NE42 W5NE42 PTHR15710:SF243 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF181 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014261.1|UniProtKB=W5NA97 W5NA97 PTHR48012:SF7 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 26 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell communication#GO:0007154;regulation of cell motility#GO:2000145;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013221.1|UniProtKB=W5N6M8 W5N6M8 PTHR21472:SF16 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 SI:DKEY-85K7.11 LEPOC|Ensembl=ENSLOCG00000005640.1|UniProtKB=W5MEK3 W5MEK3 PTHR45639:SF37 HSC70CB, ISOFORM G-RELATED HYPOXIA UP-REGULATED PROTEIN 1 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 negative regulation of programmed cell death#GO:0043069;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of biological process#GO:0050789;regulation of intrinsic apoptotic signaling pathway#GO:2001242;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cellular response to stress#GO:0080135;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534 Hsp70 family chaperone#PC00027;chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000094.1|UniProtKB=W5LVE7 W5LVE7 PTHR47230:SF1 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 positive regulation of response to external stimulus#GO:0032103;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;toll-like receptor signaling pathway#GO:0002224;positive regulation of multicellular organismal process#GO:0051240;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of gene expression#GO:0010468;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of gene expression#GO:0010628;positive regulation of response to biotic stimulus#GO:0002833;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;positive regulation of type I interferon production#GO:0032481;positive regulation of signal transduction#GO:0009967;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;positive regulation of cytokine production#GO:0001819;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TRIF#P01344 LEPOC|Ensembl=ENSLOCG00000013095.1|UniProtKB=W5N673 W5N673 PTHR14217:SF1 INOSITOL-TETRAKISPHOSPHATE 1-KINASE INOSITOL-TETRAKISPHOSPHATE 1-KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002230.1|UniProtKB=W5M2I5 W5M2I5 PTHR11880:SF2 RIBOSOMAL PROTEIN S19P FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US19 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000003305.1|UniProtKB=W5M696 W5M696 PTHR11848:SF241 TGF-BETA FAMILY ANTI-DORSALIZING MORPHOTIC PROTEIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000001073.1|UniProtKB=W5LYK5 W5LYK5 PTHR24072:SF404 RHO FAMILY GTPASE CELL DIVISION CYCLE 42 LIKE 2 ISOFORM X1 protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;actin filament organization#GO:0007015;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;localization#GO:0051179;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;Huntington disease#P00029>Rac#P00775;Integrin signalling pathway#P00034>Cdc42#P00938;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Cdc42#P04569;Axon guidance mediated by Slit/Robo#P00008>Cdc42#P00349;Axon guidance mediated by netrin#P00009>cdc42#P00364 LEPOC|Ensembl=ENSLOCG00000000851.1|UniProtKB=W5LXT6 W5LXT6 PTHR13557:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 86 COILED-COIL DOMAIN-CONTAINING PROTEIN 86 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000005472.1|UniProtKB=W5MDZ0 W5MDZ0 PTHR24347:SF394 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE 3 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;system development#GO:0048731;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;multicellular organismal process#GO:0032501;tissue development#GO:0009888;biological regulation#GO:0065007;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;developmental process#GO:0032502;cell differentiation#GO:0030154;response to stimulus#GO:0050896;circulatory system development#GO:0072359;actomyosin structure organization#GO:0031032;signaling#GO:0023052;cell development#GO:0048468;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cellular component assembly#GO:0022607;heart development#GO:0007507;cytoskeleton organization#GO:0007010;cardiac muscle cell differentiation#GO:0055007;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;striated muscle tissue development#GO:0014706 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877 LEPOC|Ensembl=ENSLOCG00000008872.1|UniProtKB=W5MQZ7 W5MQZ7 PTHR11036:SF12 SEMAPHORIN SEMAPHORIN-6A binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;regulation of neuron migration#GO:2001222;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000005343.1|UniProtKB=W5MDH9 W5MDH9 PTHR34348:SF1 SURFEIT LOCUS PROTEIN 2 SURFEIT LOCUS PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000015413.1|UniProtKB=W5NEB0 W5NEB0 PTHR31586:SF1 CYTOCHROME C OXIDASE PROTEIN 20 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000010431.1|UniProtKB=W5MWM7 W5MWM7 PTHR11639:SF141 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-B protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;signaling receptor binding#GO:0005102;binding#GO:0005488;calcium ion binding#GO:0005509 positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000009032.1|UniProtKB=W5MRJ9 W5MRJ9 PTHR46803:SF5 E3 UBIQUITIN-PROTEIN LIGASE CHIP E3 UBIQUITIN-PROTEIN LIGASE CHIP ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;protein-folding chaperone binding#GO:0051087;catalytic activity#GO:0003824;transferase activity#GO:0016740 positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;response to misfolded protein#GO:0051788;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular response to misfolded protein#GO:0071218;regulation of cellular process#GO:0050794;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to topologically incorrect protein#GO:0035967 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016;I band#GO:0031674;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>CHIP#P01214 LEPOC|Ensembl=ENSLOCG00000007744.1|UniProtKB=W5MM02 W5MM02 PTHR46051:SF2 SH2 DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 5-PHOSPHATASE 2 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of immune system process#GO:0002682;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 PI3 kinase pathway#P00048>SHIP#P01200;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SHIP#P00839;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>SHIP2#P00897 LEPOC|Ensembl=ENSLOCG00000005443.1|UniProtKB=W5MDV9 W5MDV9 PTHR24356:SF158 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C BETA TYPE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Metabotropic glutamate receptor group I pathway#P00041>PKC#P01055;Apoptosis signaling pathway#P00006>PKCs#P00318;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;B cell activation#P00010>PKC#P00373;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Endothelin signaling pathway#P00019>PKC#P00568;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;CCKR signaling map#P06959>PKCbeta#P07177;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861 LEPOC|Ensembl=ENSLOCG00000003699.1|UniProtKB=W5M7Q7 W5M7Q7 PTHR24054:SF34 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA' protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular response to stress#GO:0033554;regulation of chromosome segregation#GO:0051983;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stress#GO:0006950;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of chromosome separation#GO:1905818 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459 LEPOC|Ensembl=ENSLOCG00000017794.1|UniProtKB=W5NMN9 W5NMN9 PTHR14315:SF19 SPOT14 FAMILY MEMBER MID1-INTERACTING PROTEIN 1-B-RELATED regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of lipid biosynthetic process#GO:0046890;regulation of cellular process#GO:0050794;regulation of lipid metabolic process#GO:0019216;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000016365.1|UniProtKB=W5NHU8 W5NHU8 PTHR24240:SF148 OPSIN OPSIN-5 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;biological regulation#GO:0065007;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cellular response to radiation#GO:0071478;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008211.1|UniProtKB=W5MNL8 W5MNL8 PTHR43884:SF1 ACYL-COA DEHYDROGENASE SHORT_BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006692.1|UniProtKB=W5MI70 W5MI70 PTHR13215:SF0 RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000000710.1|UniProtKB=W5LXD4 W5LXD4 PTHR23306:SF17 TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED TUMOR SUSCEPTIBILITY GENE 101 PROTEIN binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004765.1|UniProtKB=W5MBG1 W5MBG1 PTHR12027:SF7 WNT RELATED PROTEIN WNT-11 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 LEPOC|Ensembl=ENSLOCG00000004934.1|UniProtKB=W5MC24 W5MC24 PTHR16201:SF53 SEVEN TRANSMEMBRANE PROTEIN 1-RELATED TRANSMEMBRANE PROTEIN 44 amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179 transport#GO:0006810;amino acid transport#GO:0006865;chemical homeostasis#GO:0048878;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;vacuolar transmembrane transport#GO:0034486;establishment of localization#GO:0051234;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;L-alpha-amino acid transmembrane transport#GO:1902475;homeostatic process#GO:0042592;carboxylic acid transmembrane transport#GO:1905039 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013954.1|UniProtKB=W5N992 W5N992 PPARG PTHR24082:SF488 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of lipid metabolic process#GO:0019216;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;cellular response to chemical stimulus#GO:0070887;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 CCKR signaling map#P06959>PPARgamma#P07060;Gonadotropin-releasing hormone receptor pathway#P06664>PPARalpha/gamma#P06744;Gonadotropin-releasing hormone receptor pathway#P06664>PPARgamma#P06721 LEPOC|Ensembl=ENSLOCG00000002548.1|UniProtKB=W5M3N9 W5M3N9 PTHR12345:SF9 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 3 peptide binding#GO:0042277;binding#GO:0005488 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;anterograde trans-synaptic signaling#GO:0098916;cellular process#GO:0009987;regulation of biological process#GO:0050789;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268 cell junction#GO:0030054;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cytoplasm#GO:0005737;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;dendritic spine#GO:0043197;postsynapse#GO:0098794 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093;Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084 LEPOC|Ensembl=ENSLOCG00000008957.1|UniProtKB=W5MRD0 W5MRD0 PTHR24023:SF845 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000018270.1|UniProtKB=W5NP12 W5NP12 PTHR10489:SF627 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 8 protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896 response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;chemotaxis#GO:0006935;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000003548.1|UniProtKB=W5M743 W5M743 PTHR48021:SF59 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 6 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017534.1|UniProtKB=W5NLY0 W5NLY0 PTHR24247:SF20 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1A molecular transducer activity#GO:0060089;serotonin binding#GO:0051378;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;heterocyclic compound binding#GO:1901363;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000008422.1|UniProtKB=W5MPD2 W5MPD2 PTHR22461:SF2 SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2-RELATED SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;microtubule bundle formation#GO:0001578;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000009064.1|UniProtKB=W5MRN3 W5MRN3 PTHR15337:SF1 ANTERIOR GRADIENT PROTEIN-RELATED ANTERIOR GRADIENT PROTEIN 2 HOMOLOG response to stress#GO:0006950;inflammatory response#GO:0006954;response to stimulus#GO:0050896;defense response#GO:0006952 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008386.1|UniProtKB=W5MP85 W5MP85 PTHR10878:SF6 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Angiogenesis#P00005>Dsh#P00200;Wnt signaling pathway#P00057>Dishevelled#P01447 LEPOC|Ensembl=ENSLOCG00000010061.1|UniProtKB=W5MVA4 W5MVA4 PTHR16171:SF11 DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED DNA EXCISION REPAIR PROTEIN ERCC-5 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleotide-excision repair complex#GO:0000109;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005810.1|UniProtKB=W5MF56 W5MF56 PTHR24205:SF5 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 3 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000013039.1|UniProtKB=W5N602 W5N602 PTHR33559:SF1 PROTEASOME ASSEMBLY CHAPERONE 4 PROTEASOME ASSEMBLY CHAPERONE 4 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000010925.1|UniProtKB=W5MYE4 W5MYE4 PTHR23036:SF83 CYTOKINE RECEPTOR INTERLEUKIN-6 RECEPTOR SUBUNIT BETA binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Signaling subunit#P00969 LEPOC|Ensembl=ENSLOCG00000006816.1|UniProtKB=W5MIQ0 W5MIQ0 PTHR24204:SF4 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron development#GO:0048666;axonogenesis#GO:0007409;cell fate commitment#GO:0045165;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;positive regulation of transcription by RNA polymerase II#GO:0045944;cell fate specification#GO:0001708;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;neuron fate commitment#GO:0048663;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#G06682;Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#P06791;Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#G06896 LEPOC|Ensembl=ENSLOCG00000016795.1|UniProtKB=W5NJE9 W5NJE9 PTHR45820:SF3 FI23527P1 CALCIUM_MANGANESE ANTIPORTER SLC30A10 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;zinc ion transmembrane transport#GO:0071577;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;response to metal ion#GO:0010038;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;response to chemical#GO:0042221;monoatomic cation transmembrane transport#GO:0098655;detoxification#GO:0098754;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;response to stress#GO:0006950;detoxification of inorganic compound#GO:0061687;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015407.1|UniProtKB=W5NEA8 W5NEA8 PTHR22891:SF188 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 2 binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;RNA binding#GO:0003723;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;male gamete generation#GO:0048232;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000011180.1|UniProtKB=W5MZD4 W5MZD4 PTHR13510:SF44 FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED RABENOSYN-5 LEPOC|Ensembl=ENSLOCG00000013855.1|UniProtKB=W5N8Y1 W5N8Y1 PTHR22957:SF547 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 16 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000012744.1|UniProtKB=W5N4W9 W5N4W9 PTHR15240:SF4 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 4 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane#GO:0016020;membrane raft#GO:0045121;caveola#GO:0005901;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane microdomain#GO:0098857;plasma membrane raft#GO:0044853;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003695.1|UniProtKB=W5M7Q2 W5M7Q2 PTHR13265:SF1 THO COMPLEX SUBUNIT 1 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 8 mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;transcription export complex#GO:0000346;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018226.1|UniProtKB=W5NNW8 W5NNW8 PTHR24409:SF451 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 431-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000005581.1|UniProtKB=W5MED1 W5MED1 PTHR23257:SF707 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 12 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000015782.1|UniProtKB=W5NFM1 W5NFM1 PTHR10091:SF0 ALDOSE-1-EPIMERASE GALACTOSE MUTAROTASE racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;isomerase activity#GO:0016853 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glucose metabolic process#GO:0006006;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 epimerase/racemase#PC00096 LEPOC|Ensembl=ENSLOCG00000004851.1|UniProtKB=W5MBU0 W5MBU0 PTHR10073:SF57 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL DNA MISMATCH REPAIR PROTEIN MLH1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;DNA endonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;nuclease activity#GO:0004518 multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;developmental process#GO:0032502;multicellular organismal process#GO:0032501;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;anatomical structure development#GO:0048856;immune system development#GO:0002520;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;cellular response to stress#GO:0033554;production of molecular mediator of immune response#GO:0002440;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mismatch repair#GO:0006298;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016809.1|UniProtKB=W5NJH4 W5NJH4 PTHR10807:SF43 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 5 guanyl-nucleotide exchange factor activity#GO:0005085;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;phosphoric ester hydrolase activity#GO:0042578;molecular function regulator activity#GO:0098772 phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;dephosphorylation#GO:0016311;lipid modification#GO:0030258;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650 membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004408.1|UniProtKB=W5MA57 W5MA57 PTHR31259:SF3 ENDOSOME-ASSOCIATED TRAFFICKING REGULATOR 1 ENDOSOME-ASSOCIATED-TRAFFICKING REGULATOR 1 regulation of biological process#GO:0050789;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;recycling endosome#GO:0055037;centrosome#GO:0005813;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;midbody#GO:0030496;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001917.1|UniProtKB=W5M1G7 W5M1G7 PTHR13388:SF28 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132C ISOFORM X1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000008430.1|UniProtKB=W5MPF0 W5MPF0 PTHR45762:SF4 ZINC FINGER RNA-BINDING PROTEIN INTERLEUKIN ENHANCER-BINDING FACTOR 3 RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008833.1|UniProtKB=W5MQU4 W5MQU4 PTHR43176:SF38 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity#GO:0003824;deacylase activity#GO:0160215;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003007.1|UniProtKB=W5M598 W5M598 PTHR46769:SF2 POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1 PKHD1 LIKE 1, TANDEM DUPLICATE 1 PRECURSOR-RELATED LEPOC|Ensembl=ENSLOCG00000015416.1|UniProtKB=W5NEB4 W5NEB4 PTHR12191:SF5 SOLUTE CARRIER FAMILY 39 METAL CATION SYMPORTER ZIP14 transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;intracellular monoatomic ion homeostasis#GO:0006873;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000725.1|UniProtKB=W5LXF0 W5LXF0 PTHR10812:SF13 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-EPSILON sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010555.1|UniProtKB=W5MX26 W5MX26 PTHR23119:SF46 DISCS LARGE ERBIN protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cell-cell adhesion#GO:0098609;intracellular protein localization#GO:0008104;localization#GO:0051179;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cellular localization#GO:0051641;cell adhesion#GO:0007155;receptor clustering#GO:0043113;localization within membrane#GO:0051668;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088 anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006188.1|UniProtKB=W5MGG7 W5MGG7 PTHR23267:SF486 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14_DELTA VARIABLE 4 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006398.1|UniProtKB=W5MH68 W5MH68 PTHR46607:SF1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 phospholipid binding#GO:0005543;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 LEPOC|Ensembl=ENSLOCG00000008919.1|UniProtKB=W5MR51 W5MR51 PTHR23004:SF5 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2 regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cilium organization#GO:0044782;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of cilium assembly#GO:1902017;regulation of cellular process#GO:0050794;cell motility#GO:0048870;anatomical structure development#GO:0048856;regulation of cell projection assembly#GO:0060491;system development#GO:0048731;organelle assembly#GO:0070925;cell migration#GO:0016477;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;cellular developmental process#GO:0048869;neuron migration#GO:0001764;regulation of plasma membrane bounded cell projection organization#GO:0120035;neurogenesis#GO:0022008;plasma membrane bounded cell projection assembly#GO:0120031;regulation of cell projection organization#GO:0031344;developmental process#GO:0032502 cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;cluster of actin-based cell projections#GO:0098862;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014 LEPOC|Ensembl=ENSLOCG00000011279.1|UniProtKB=W5MZQ3 W5MZQ3 TRAF3IP3 PTHR15715:SF21 CENTROSOMAL PROTEIN OF 170 KDA TRAF3-INTERACTING JNK-ACTIVATING MODULATOR molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;intracellular receptor signaling pathway#GO:0030522;response to external biotic stimulus#GO:0043207;innate immune response-activating signaling pathway#GO:0002758;antiviral innate immune response#GO:0140374;cellular response to stimulus#GO:0051716;response to virus#GO:0009615;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;negative regulation of signal transduction#GO:0009968;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;response to stimulus#GO:0050896;regulation of hippo signaling#GO:0035330;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;negative regulation of biological process#GO:0048519;defense response to virus#GO:0051607;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008067.1|UniProtKB=W5MN50 W5MN50 PTHR19288:SF44 4-NITROPHENYLPHOSPHATASE-RELATED PHOSPHOLYSINE PHOSPHOHISTIDINE INORGANIC PYROPHOSPHATE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity, acting on acid anhydrides#GO:0016817;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005534.1|UniProtKB=W5ME78 W5ME78 PTHR11601:SF62 CYSTEINE DESULFURYLASE FAMILY MEMBER SELENOCYSTEINE LYASE metabolite interconversion enzyme#PC00262;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000000682.1|UniProtKB=W5LX95 W5LX95 PTHR45598:SF5 PROTEIN CBG11839-RELATED 4FE-4S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010551.1|UniProtKB=W5MX23 W5MX23 PTHR13396:SF3 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY-INTERACTING PROTEIN 1 regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of protein ubiquitination#GO:0031396;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of protein modification process#GO:0031399;regulation of protein modification by small protein conjugation or removal#GO:1903320;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;perinuclear region of cytoplasm#GO:0048471;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000005174.1|UniProtKB=W5MCX6 W5MCX6 PTHR45620:SF4 PDF RECEPTOR-LIKE PROTEIN-RELATED CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tube development#GO:0035295;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;cell communication#GO:0007154;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;blood vessel morphogenesis#GO:0048514;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010690.1|UniProtKB=W5MXI8 W5MXI8 PTHR18945:SF498 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2 ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;chloride transport#GO:0006821;cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cellular process#GO:0009987;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;animal gross anatomical part developmental process#GO:0160108;synapse assembly#GO:0007416;signaling#GO:0023052;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 leading edge membrane#GO:0031256;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection membrane#GO:0031253;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000006331.1|UniProtKB=W5MH34 W5MH34 PTHR14340:SF13 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 TITIN developmental process#GO:0032502;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;multicellular organismal process#GO:0032501;tissue development#GO:0009888;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;system development#GO:0048731;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;heart development#GO:0007507;cellular component assembly#GO:0022607;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;circulatory system development#GO:0072359;cell differentiation#GO:0030154 M band#GO:0031430;intracellular organelle#GO:0043229;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;A band#GO:0031672;contractile muscle fiber#GO:0043292;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000000268.1|UniProtKB=W5LVY9 W5LVY9 PTHR19282:SF576 TETRASPANIN TETRASPANIN cell motility#GO:0048870;cell migration#GO:0016477;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014208.1|UniProtKB=W5NA43 W5NA43 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007405.1|UniProtKB=W5MKS6 W5MKS6 PTHR23049:SF9 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2, VENTRICULAR_CARDIAC MUSCLE ISOFORM calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022 heart development#GO:0007507;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular developmental process#GO:0048869;heart contraction#GO:0060047;system process#GO:0003008;developmental process#GO:0032502;muscle contraction#GO:0006936;cell fate specification#GO:0001708;cell differentiation#GO:0030154;circulatory system development#GO:0072359;muscle structure development#GO:0061061;striated muscle contraction#GO:0006941;muscle cell differentiation#GO:0042692;muscle system process#GO:0003012;heart process#GO:0003015;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;circulatory system process#GO:0003013;cardiac muscle contraction#GO:0060048 myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;myosin complex#GO:0016459;contractile muscle fiber#GO:0043292 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006394.1|UniProtKB=W5MH65 W5MH65 PTHR19143:SF45 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008240.1|UniProtKB=W5MNP9 W5MNP9 PTHR14167:SF31 SH3 DOMAIN-CONTAINING NOSTRIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017211.1|UniProtKB=W5NKX0 W5NKX0 PTHR11278:SF0 40S RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN ES7 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;small-subunit processome#GO:0032040;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000013516.1|UniProtKB=W5N7S0 W5N7S0 PTHR28678:SF1 CODANIN-1 CODANIN-1 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000005539.1|UniProtKB=W5ME92 W5ME92 PTHR14695:SF8 SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED SHC SH2 DOMAIN-BINDING PROTEIN 1 regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;cell division#GO:0051301;organelle fission#GO:0048285;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;fibroblast growth factor receptor signaling pathway#GO:0008543;male gamete generation#GO:0048232;biological regulation#GO:0065007;meiotic nuclear division#GO:0140013;response to fibroblast growth factor#GO:0071774;spermatogenesis#GO:0007283;developmental process#GO:0032502;gamete generation#GO:0007276;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;response to endogenous stimulus#GO:0009719;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cytoskeleton-dependent cytokinesis#GO:0061640;cellular response to growth factor stimulus#GO:0071363;cytokinesis#GO:0000910;nuclear division#GO:0000280;male meiotic nuclear division#GO:0007140;organelle organization#GO:0006996;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;meiotic cell cycle#GO:0051321;cell surface receptor signaling pathway#GO:0007166 LEPOC|Ensembl=ENSLOCG00000005128.1|UniProtKB=W5MCR5 W5MCR5 PTHR24020:SF16 COLLAGEN ALPHA MATRILIN-1 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000001203.1|UniProtKB=W5LZ14 W5LZ14 PTHR12801:SF62 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 1 HOMOLOG catalytic activity#GO:0003824;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000009965.1|UniProtKB=W5MV00 W5MV00 PTHR11801:SF18 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA_BETA transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cytokine-mediated signaling pathway#GO:0019221;response to bacterium#GO:0009617;lipopolysaccharide-mediated signaling pathway#GO:0031663;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;regulation of gene expression#GO:0010468;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;cellular response to molecule of bacterial origin#GO:0071219;immune response#GO:0006955;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;response to peptide hormone#GO:0043434;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to oxygen-containing compound#GO:1901700;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;interleukin-7-mediated signaling pathway#GO:0038111;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607;cell surface receptor signaling pathway via STAT#GO:0097696;interleukin-9-mediated signaling pathway#GO:0038113;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832;JAK/STAT signaling pathway#P00038>STAT#P01027;Oxidative stress response#P00046>Stat1#P01125;Oxidative stress response#P00046>Myc#P01124;EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173;Interferon-gamma signaling pathway#P00035>STAT1#P00961;Angiogenesis#P00005>STAT1#P00218;Ras Pathway#P04393>Stat 1/3#P04566;p53 pathway feedback loops 2#P04398>Myc#P04649;Interleukin signaling pathway#P00036>STAT#P00996 LEPOC|Ensembl=ENSLOCG00000007276.1|UniProtKB=W5MK95 W5MK95 PTHR24327:SF29 HOMEOBOX PROTEIN HOMEOBOX PROTEIN VENTX sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010719.1|UniProtKB=W5MXM4 W5MXM4 PTHR48014:SF13 SERINE/THREONINE-PROTEIN KINASE FRAY2 STE20-RELATED KINASE ADAPTER PROTEIN BETA enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;protein transport#GO:0015031;nuclear transport#GO:0051169 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;protein-containing complex#GO:0032991 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000003131.1|UniProtKB=W5M5M8 W5M5M8 PTHR46987:SF4 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-2 signaling receptor binding#GO:0005102;receptor serine/threonine kinase binding#GO:0033612;binding#GO:0005488;protein binding#GO:0005515 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001014.1|UniProtKB=W5LYG0 W5LYG0 PTHR44360:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular organelle lumen#GO:0070013 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008869.1|UniProtKB=W5MQY4 W5MQY4 PTHR46909:SF1 39S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL36M mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000013670.1|UniProtKB=W5N8A2 W5N8A2 PTHR18871:SF2 CENTROSOMAL PROTEIN OF 112 KDA CENTROSOMAL PROTEIN OF 112 KDA LEPOC|Ensembl=ENSLOCG00000002821.1|UniProtKB=W5M4L1 W5M4L1 PTHR44699:SF2 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11 ZGC:165604 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003690.1|UniProtKB=W5M7M1 W5M7M1 PTHR24229:SF2 NEUROPEPTIDES RECEPTOR DELTA-TYPE OPIOID RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;binding#GO:0005488 neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Opioid proopiomelanocortin pathway#P05917>Mu or Delta receptor#P06004;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Enkephalin release#P05913>GPCR (i)#P05973;Opioid proenkephalin pathway#P05915>Mu or Delta receptor#P05985;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000014510.1|UniProtKB=W5NB61 W5NB61 PTHR18978:SF1 GRIP-1 ASSOCIATED PROTEIN 1 GRIP1-ASSOCIATED PROTEIN 1 regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of establishment of protein localization#GO:0070201;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;regulation of vesicle-mediated transport#GO:0060627;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;vesicle#GO:0031982;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;early endosome membrane#GO:0031901;synaptic membrane#GO:0097060;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;glutamatergic synapse#GO:0098978;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000005367.1|UniProtKB=W5MDL2 W5MDL2 PTHR24251:SF26 OVOCHYMASE-RELATED NEUROPILIN AND TOLLOID-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;protein localization to cell junction#GO:1902414;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;macromolecule localization#GO:0033036;cellular process#GO:0009987;regulation of protein localization to membrane#GO:1905475;biological regulation#GO:0065007;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;protein localization to cell periphery#GO:1990778;protein localization to synapse#GO:0035418;regulation of localization#GO:0032879;intracellular protein localization#GO:0008104 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005282.1|UniProtKB=W5MDA4 W5MDA4 PTHR31564:SF0 ANAPHASE-PROMOTING COMPLEX SUBUNIT 16 ANAPHASE-PROMOTING COMPLEX SUBUNIT 16 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;kinetochore#GO:0000776;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;transferase complex#GO:1990234;supramolecular complex#GO:0099080;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000016602.1|UniProtKB=W5NIP6 W5NIP6 PTHR24083:SF98 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP E MEMBER 1 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000007820.1|UniProtKB=W5MM96 W5MM96 PTHR10799:SF76 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 4 catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;heterochromatin organization#GO:0070828;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009;DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000001432.1|UniProtKB=W5LZT0 W5LZT0 PTHR23288:SF8 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;regulation of DNA-templated transcription elongation#GO:0032784;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;snRNA transcription#GO:0009301;regulation of biological process#GO:0050789;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000009422.1|UniProtKB=W5MSY9 W5MSY9 PTHR16821:SF2 FRATAXIN FRATAXIN, MITOCHONDRIAL cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000006880.1|UniProtKB=W5MIW0 W5MIW0 PTHR23411:SF41 TAPASIN IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012019.1|UniProtKB=W5N2C3 W5N2C3 PTHR46925:SF1 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED NEUROMEDIN-K RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 regulation of microtubule-based process#GO:0032886;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;positive regulation of cell motility#GO:2000147;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of microtubule-based movement#GO:0060632;regulation of reproductive process#GO:2000241;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012 membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001996.1|UniProtKB=W5M1P7 W5M1P7 PTHR24366:SF54 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IMMUNOGLOBULIN SUPERFAMILY MEMBER 10 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000012380.1|UniProtKB=W5N3N1 W5N3N1 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010065.1|UniProtKB=W5MVB3 W5MVB3 PTHR46079:SF1 FERM DOMAIN-CONTAINING PROTEIN 4 FERM DOMAIN-CONTAINING PROTEIN 4B cell-cell junction#GO:0005911;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;anchoring junction#GO:0070161;adherens junction#GO:0005912;tight junction#GO:0070160;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000006415.1|UniProtKB=W5MH90 W5MH90 PTHR13193:SF0 CGI-140 PAT COMPLEX SUBUNIT ASTERIX localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of protein localization#GO:0045184;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000016720.1|UniProtKB=W5NJ54 W5NJ54 PTHR19375:SF438 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 14 heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515 protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027;chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001087.1|UniProtKB=W5LYL8 W5LYL8 PTHR14949:SF52 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 VON WILLEBRAND FACTOR D AND EGF DOMAIN-CONTAINING PROTEIN signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007548.1|UniProtKB=W5MLB1 W5MLB1 PTHR14826:SF12 ANGIOMOTIN ANGIOMOTIN-LIKE PROTEIN 1 establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;angiogenesis#GO:0001525;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;signaling#GO:0023052;circulatory system development#GO:0072359;response to stimulus#GO:0050896;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;hippo signaling#GO:0035329;actin filament-based process#GO:0030029;system development#GO:0048731;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;establishment of cell polarity#GO:0030010;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;regulation of cell migration#GO:0030334;developmental process#GO:0032502;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;cell migration#GO:0016477 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cytoplasm#GO:0005737;bicellular tight junction#GO:0005923 LEPOC|Ensembl=ENSLOCG00000007069.1|UniProtKB=W5MJJ8 W5MJJ8 PTHR23036:SF16 CYTOKINE RECEPTOR CYTOKINE RECEPTOR-LIKE FACTOR 1 protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;negative regulation of neuron apoptotic process#GO:0043524;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;negative regulation of apoptotic process#GO:0043066;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;negative regulation of cellular process#GO:0048523 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular protein-containing complex#GO:0140392;signaling receptor complex#GO:0043235;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007733.1|UniProtKB=W5MLY0 W5MLY0 PTHR13495:SF0 NEFA-INTERACTING NUCLEAR PROTEIN NIP30 PSME3-INTERACTING PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000003655.1|UniProtKB=W5M7J5 W5M7J5 PTHR24115:SF1046 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF17 ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;axo-dendritic transport#GO:0008088;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000014420.1|UniProtKB=W5NAU2 W5NAU2 PTHR46223:SF4 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE-RELATED protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000007096.1|UniProtKB=W5MJN3 W5MJN3 PTHR43391:SF1 RETINOL DEHYDROGENASE-RELATED RETINOL DEHYDROGENASE 8 ISOFORM X1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000006272.1|UniProtKB=W5MGR3 W5MGR3 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002879.1|UniProtKB=W5M4T3 W5M4T3 PTHR34755:SF2 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED SERINE_ARGININE REPETITIVE MATRIX PROTEIN 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 LEPOC|Ensembl=ENSLOCG00000001949.1|UniProtKB=W5M1L2 W5M1L2 PTHR12086:SF11 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2 biological regulation#GO:0065007;nervous system development#GO:0007399;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;neuromuscular junction development#GO:0007528;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;developmental growth#GO:0048589;developmental process#GO:0032502;growth#GO:0040007;regulation of cell projection organization#GO:0031344;regulation of developmental process#GO:0050793;regulation of cellular component organization#GO:0051128;regulation of dendrite development#GO:0050773;synapse assembly#GO:0007416;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of dendrite morphogenesis#GO:0048814;system development#GO:0048731;anatomical structure development#GO:0048856;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;cytoplasmic microtubule#GO:0005881;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000016499.1|UniProtKB=W5NIC3 W5NIC3 PTHR10582:SF33 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN ION TRANSPORT DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;import into cell#GO:0098657;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009500.1|UniProtKB=W5MT95 W5MT95 PTHR12907:SF28 EGL NINE HOMOLOG-RELATED PROLYL HYDROXYLASE EGLN3 catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;ferrous iron binding#GO:0008198;catalytic activity#GO:0003824;cation binding#GO:0043169;dioxygenase activity#GO:0051213;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;regulation of programmed cell death#GO:0043067;cellular response to hypoxia#GO:0071456;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to hypoxia#GO:0001666;regulation of apoptotic process#GO:0042981;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 LEPOC|Ensembl=ENSLOCG00000010841.1|UniProtKB=W5MY34 W5MY34 PTHR46569:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRAIP E3 UBIQUITIN-PROTEIN LIGASE TRAIP ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 replication fork processing#GO:0031297;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication#GO:0006260;protein modification by small protein conjugation#GO:0032446;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;DNA-templated DNA replication#GO:0006261;protein modification by small protein conjugation or removal#GO:0070647 site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009255.1|UniProtKB=W5MSC9 W5MSC9 PTHR12729:SF6 TRNA(HIS) GUANYLYLTRANSFERASE-RELATED TRNA(HIS) GUANYLYLTRANSFERASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 LEPOC|Ensembl=ENSLOCG00000018158.1|UniProtKB=W5NNQ0 W5NNQ0 PTHR24228:SF67 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR APELIN RECEPTOR 2 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;heart development#GO:0007507;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;vasculature development#GO:0001944;multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental process#GO:0032502;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017327.1|UniProtKB=W5NLC3 W5NLC3 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009343.1|UniProtKB=W5MSN9 W5MSN9 PTHR24020:SF29 COLLAGEN ALPHA COLLAGEN ALPHA-2(VI) CHAIN extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000011171.1|UniProtKB=W5MZB8 W5MZB8 PTHR45752:SF4 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 59 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006145.1|UniProtKB=W5MGD9 W5MGD9 PTHR12305:SF102 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;vasculature development#GO:0001944;multicellular organism development#GO:0007275;blood vessel development#GO:0001568;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;system development#GO:0048731;anatomical structure development#GO:0048856 nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;protein phosphatase#PC00195 PI3 kinase pathway#P00048>PTEN#P01189;p53 pathway#P00059>PTEN#P01480;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway feedback loops 2#P04398>PTEN#P04658;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;p53 pathway feedback loops 2#P04398>PTEN#G04714;CCKR signaling map#P06959>PTEN#P07071;Hypoxia response via HIF activation#P00030>PTEN#P00824;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PTEN#P00849;p53 pathway#P00059>PTEN#G01579 LEPOC|Ensembl=ENSLOCG00000004116.1|UniProtKB=W5M962 W5M962 LRRC41 PTHR15354:SF1 MUF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 41 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;Cul5-RING ubiquitin ligase complex#GO:0031466;ubiquitin ligase complex#GO:0000151 LEPOC|Ensembl=ENSLOCG00000017596.1|UniProtKB=W5NM42 W5NM42 PTHR22794:SF2 THAP DOMAIN PROTEIN 11 THAP DOMAIN-CONTAINING PROTEIN 11 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000001219.1|UniProtKB=W5LZ64 W5LZ64 PTHR13102:SF0 NUCLEOLAR PROTEIN 9 NUCLEOLAR PROTEIN 9 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;establishment of organelle localization#GO:0051656;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;intracellular transport#GO:0046907;rRNA metabolic process#GO:0016072;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organelle localization#GO:0051640;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;localization#GO:0051179;nuclear transport#GO:0051169;nuclear export#GO:0051168;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;90S preribosome#GO:0030686;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015325.1|UniProtKB=W5NDZ9 W5NDZ9 PTHR15260:SF1 SARCOSPAN SARCOSPAN membrane#GO:0016020;cell periphery#GO:0071944;sarcolemma#GO:0042383;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015600.1|UniProtKB=W5NEZ7 W5NEZ7 PTHR10844:SF3 CAVEOLIN CAVEOLIN-2 kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;intracellular monoatomic ion homeostasis#GO:0006873;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;membrane assembly#GO:0071709;cellular response to hormone stimulus#GO:0032870;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;calcium ion homeostasis#GO:0055074;cellular response to chemical stimulus#GO:0070887;inorganic ion homeostasis#GO:0098771;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;plasma membrane organization#GO:0007009;response to hormone#GO:0009725;monoatomic ion homeostasis#GO:0050801;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;chemical homeostasis#GO:0048878;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;intracellular calcium ion homeostasis#GO:0006874;response to insulin#GO:0032868;regulation of cytosolic calcium ion concentration#GO:0051480;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;homeostatic process#GO:0042592;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to nitrogen compound#GO:1901698;negative regulation of cell population proliferation#GO:0008285;cellular response to nitrogen compound#GO:1901699;response to peptide hormone#GO:0043434;membrane organization#GO:0061024;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;monoatomic cation homeostasis#GO:0055080;cellular response to insulin stimulus#GO:0032869;intracellular monoatomic cation homeostasis#GO:0030003;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 Golgi apparatus#GO:0005794;membrane microdomain#GO:0098857;cell junction#GO:0030054;sarcolemma#GO:0042383;caveola#GO:0005901;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;plasma membrane raft#GO:0044853;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;anchoring junction#GO:0070161;intracellular vesicle#GO:0097708;membrane raft#GO:0045121;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013542.1|UniProtKB=W5N7U3 W5N7U3 PTHR22545:SF0 CENTROSOMAL PROTEIN OF 95 KDA CENTROSOMAL PROTEIN OF 95 KDA membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000008546.1|UniProtKB=W5MPU3 W5MPU3 PTHR10869:SF101 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018110.1|UniProtKB=W5NNK2 W5NNK2 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013802.1|UniProtKB=W5N8R4 W5N8R4 PTHR20948:SF5 TRANSMEMBRANE PROTEIN 164 TRANSMEMBRANE PROTEIN 164 positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 LEPOC|Ensembl=ENSLOCG00000016165.1|UniProtKB=W5NH11 W5NH11 PTHR43788:SF19 DNA2/NAM7 HELICASE FAMILY MEMBER DNA HELICASE B catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 response to stress#GO:0006950;cellular process#GO:0009987;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of double-strand break repair via homologous recombination#GO:2000042;regulation of double-strand break repair via homologous recombination#GO:0010569;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;DNA-templated DNA replication#GO:0006261;regulation of cellular response to stress#GO:0080135;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of DNA metabolic process#GO:0051053;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of DNA recombination#GO:0045910;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;regulation of double-strand break repair#GO:2000779 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008399.1|UniProtKB=W5MP97 W5MP97 PTHR45726:SF2 LEUKOTRIENE A-4 HYDROLASE AMINOPEPTIDASE RNPEPL1 exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 LEPOC|Ensembl=ENSLOCG00000003963.1|UniProtKB=W5M8M2 W5M8M2 PTHR11932:SF180 CULLIN CULLIN-3 enzyme binding#GO:0019899;protein complex scaffold activity#GO:0140378;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625;structural molecule activity#GO:0005198;protein binding#GO:0005515 protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009116.1|UniProtKB=W5MRV8 W5MRV8 PTHR14189:SF0 PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED PROTEIN PHOSPHATASE METHYLESTERASE 1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004095.1|UniProtKB=W5M941 W5M941 PTHR12174:SF23 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cytoplasmic side of membrane#GO:0098562;endomembrane system#GO:0012505;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;cytoplasm#GO:0005737;membrane#GO:0016020 protein modifying enzyme#PC00260;aspartic protease#PC00053 LEPOC|Ensembl=ENSLOCG00000015403.1|UniProtKB=W5NE93 W5NE93 PTHR10528:SF18 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 system process#GO:0003008;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;nervous system process#GO:0050877;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear speck#GO:0016607;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000003501.1|UniProtKB=W5M6Y5 W5M6Y5 PTHR21521:SF0 AMUN, ISOFORM A AMUN, ISOFORM A LEPOC|Ensembl=ENSLOCG00000016015.1|UniProtKB=W5NGG7 W5NGG7 PTHR45942:SF1 Calcineurin subunit B PROTEIN PHOSPHATASE 3 REGULATORY SUBUNIT B, ALPHA molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;calcineurin-mediated signaling#GO:0097720;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 Wnt signaling pathway#P00057>Calcineurin#P01446 LEPOC|Ensembl=ENSLOCG00000018051.1|UniProtKB=W5NNE3 W5NNE3 PTHR12002:SF24 CLAUDIN CLAUDIN-8 transporter activity#GO:0005215;paracellular tight junction channel activity#GO:0160187 cell-cell junction assembly#GO:0007043;transport#GO:0006810;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;paracellular transport#GO:0160184;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000004846.1|UniProtKB=W5MBR2 W5MBR2 PTHR13318:SF273 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 14 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000010014.1|UniProtKB=W5MV60 W5MV60 PTHR43806:SF14 PEPTIDASE S8 TRIPEPTIDYL-PEPTIDASE 2 serine-type peptidase activity#GO:0008236;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000009463.1|UniProtKB=W5MT45 W5MT45 PTHR11913:SF53 COFILIN-RELATED COFILIN 2 (MUSCLE)-RELATED protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;protein depolymerization#GO:0051261;actin cytoskeleton organization#GO:0030036;actin filament depolymerization#GO:0030042;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000016183.1|UniProtKB=W5NH36 W5NH36 PTHR12546:SF32 FER-1-LIKE OTOFERLIN small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;protein-containing complex binding#GO:0044877;cation binding#GO:0043169 sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;system process#GO:0003008;response to external stimulus#GO:0009605;establishment of localization#GO:0051234;response to mechanical stimulus#GO:0009612;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465;nervous system process#GO:0050877;secretion by cell#GO:0032940;plasma membrane organization#GO:0007009;cellular localization#GO:0051641;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;cellular component organization#GO:0016043;export from cell#GO:0140352;signaling#GO:0023052;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192 intracellular vesicle#GO:0097708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;secretory vesicle#GO:0099503;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;synaptic membrane#GO:0097060;cell junction#GO:0030054;presynaptic active zone#GO:0048786;bounding membrane of organelle#GO:0098588;presynaptic active zone membrane#GO:0048787;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;organelle membrane#GO:0031090 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000012629.1|UniProtKB=W5N4I8 W5N4I8 PTHR21396:SF2 39S RIBOSOMAL PROTEIN L43 LARGE RIBOSOMAL SUBUNIT PROTEIN ML43 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000013067.1|UniProtKB=W5N635 W5N635 PTHR24230:SF13 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 2 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011042.1|UniProtKB=W5MYU8 W5MYU8 PTHR14058:SF10 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 3 binding#GO:0005488;peptide binding#GO:0042277 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126 LEPOC|Ensembl=ENSLOCG00000010255.1|UniProtKB=W5MVZ4 W5MVZ4 PTHR11134:SF4 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-4 COMPLEX SUBUNIT BETA-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;AP-type membrane coat adaptor complex#GO:0030119;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012295.1|UniProtKB=W5N3B7 W5N3B7 PTHR22923:SF125 CEREBELLIN-RELATED C1Q AND TNF RELATED 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003124.1|UniProtKB=W5M5M3 W5M5M3 PTHR21600:SF81 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD4, MITOCHONDRIAL isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000006854.1|UniProtKB=W5MIS7 W5MIS7 PTHR14614:SF172 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;lysine N-methyltransferase activity#GO:0016278;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005115.1|UniProtKB=W5MCR3 W5MCR3 PTHR24023:SF58 COLLAGEN ALPHA COLLAGEN ALPHA-1(II) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 multicellular organismal process#GO:0032501;skeletal system morphogenesis#GO:0048705;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;system development#GO:0048731;external encapsulating structure organization#GO:0045229;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062 interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000015995.1|UniProtKB=W5NGD9 W5NGD9 PTHR47146:SF1 OTORAPLIN OTORAPLIN animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;cartilage development#GO:0051216;connective tissue development#GO:0061448;system development#GO:0048731;skeletal system morphogenesis#GO:0048705;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;multicellular organismal process#GO:0032501;tissue development#GO:0009888;animal organ morphogenesis#GO:0009887 LEPOC|Ensembl=ENSLOCG00000011563.1|UniProtKB=W5N0P9 W5N0P9 PTHR13154:SF2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 translation regulator activity#GO:0045182 negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of translation#GO:0017148 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009776.1|UniProtKB=W5MUA1 W5MUA1 PTHR13697:SF14 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, LIVER TYPE carbohydrate kinase activity#GO:0019200;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031 intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 transferase#PC00220;carbohydrate kinase#PC00065;kinase#PC00137 Glycolysis#P00024>Phosphofructokinase-1#P00672 LEPOC|Ensembl=ENSLOCG00000005129.1|UniProtKB=W5MCS2 W5MCS2 PTHR14049:SF1 LEPRECAN 1 PROLYL 3-HYDROXYLASE 2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular process#GO:0009987;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000016051.1|UniProtKB=W5NGL5 W5NGL5 PTHR43038:SF3 ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1 ABC TRANSPORTER G FAMILY MEMBER 23 ISOFORM X1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000017742.1|UniProtKB=W5NMI7 W5NMI7 PTHR11214:SF19 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 2 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000005098.1|UniProtKB=W5MCN3 W5MCN3 PTHR13268:SF0 BREAST CARCINOMA AMPLIFIED SEQUENCE 3 BCAS3 MICROTUBULE ASSOCIATED CELL MIGRATION FACTOR enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;metabolic process#GO:0008152;catabolic process#GO:0009056;response to stimulus#GO:0050896;macroautophagy#GO:0016236;response to nutrient levels#GO:0031667;response to starvation#GO:0042594;organelle organization#GO:0006996;response to stress#GO:0006950;cellular component organization#GO:0016043;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000015174.1|UniProtKB=W5NDG2 W5NDG2 PTHR23049:SF39 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2, ATRIAL ISOFORM metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092 circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;muscle tissue development#GO:0060537;system development#GO:0048731;anatomical structure development#GO:0048856;heart process#GO:0003015;circulatory system development#GO:0072359;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;system process#GO:0003008;heart contraction#GO:0060047;cardiac muscle tissue development#GO:0048738;animal organ development#GO:0048513;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;tissue development#GO:0009888;heart development#GO:0007507;blood circulation#GO:0008015 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;contractile muscle fiber#GO:0043292;myosin complex#GO:0016459;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000011785.1|UniProtKB=W5N1K5 W5N1K5 PTHR12930:SF0 ZINC FINGER PROTEIN 183 RING FINGER PROTEIN 113A1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000016286.1|UniProtKB=W5NHJ1 W5NHJ1 PTHR21448:SF0 SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000009814.1|UniProtKB=W5MUF3 W5MUF3 PTHR11932:SF68 CULLIN CULLIN-4A enzyme binding#GO:0019899;protein complex scaffold activity#GO:0140378;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;structural molecule activity#GO:0005198;protein binding#GO:0005515 protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;ribonucleoprotein complex biogenesis#GO:0022613;protein modification by small protein conjugation or removal#GO:0070647;ribosome biogenesis#GO:0042254;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013211.1|UniProtKB=W5N6L8 W5N6L8 PTHR45620:SF16 PDF RECEPTOR-LIKE PROTEIN-RELATED GROWTH HORMONE-RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000611.1|UniProtKB=W5LX14 W5LX14 PTHR45786:SF74 DNA BINDING PROTEIN-LIKE ATP-DEPENDENT DNA HELICASE LEPOC|Ensembl=ENSLOCG00000008072.1|UniProtKB=W5MN44 W5MN44 PTHR22883:SF22 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC11-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 localization#GO:0051179;cellular localization#GO:0051641;response to virus#GO:0009615;immune system process#GO:0002376;localization within membrane#GO:0051668;response to stimulus#GO:0050896;protein targeting#GO:0006605;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to virus#GO:0051607;antiviral innate immune response#GO:0140374;innate immune response#GO:0045087;establishment of localization#GO:0051234;response to external stimulus#GO:0009605;defense response#GO:0006952;protein targeting to membrane#GO:0006612;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;establishment of protein localization to membrane#GO:0090150;response to stress#GO:0006950;defense response to symbiont#GO:0140546;establishment of protein localization#GO:0045184;immune response#GO:0006955;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011268.1|UniProtKB=W5MZN7 W5MZN7 PTHR12480:SF32 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6 transport#GO:0006810;phagocytosis#GO:0006909;import into cell#GO:0098657;endocytosis#GO:0006897;establishment of localization#GO:0051234;localization#GO:0051179 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002579.1|UniProtKB=W5M3S7 W5M3S7 SUCLG1 PTHR11117:SF2 SUCCINYL-COA LIGASE SUBUNIT ALPHA SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;cellular process#GO:0009987;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;ligase#PC00142 TCA cycle#P00051>Succinyl CoA Synthetase#P01274 LEPOC|Ensembl=ENSLOCG00000012522.1|UniProtKB=W5N470 W5N470 PTHR13803:SF6 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24D zinc ion binding#GO:0008270;SNARE binding#GO:0000149;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle membrane#GO:0030658;vesicle coat#GO:0030120;cytoplasm#GO:0005737;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;coated membrane#GO:0048475;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000016591.1|UniProtKB=W5NIN8 W5NIN8 PTHR11042:SF75 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of organelle organization#GO:0033043;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of reproductive process#GO:2000241;regulation of nuclear division#GO:0051783;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013596.1|UniProtKB=W5N815 W5N815 PTHR23140:SF5 RNA PROCESSING PROTEIN LD23810P ZGC:163098 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000003076.1|UniProtKB=W5M5G5 W5M5G5 PTHR48043:SF140 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2A1 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;glucuronosyltransferase activity#GO:0015020;catalytic activity#GO:0003824;transferase activity#GO:0016740 LEPOC|Ensembl=ENSLOCG00000016983.1|UniProtKB=W5NK36 W5NK36 PTHR13832:SF287 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1H hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000004040.1|UniProtKB=W5M8W5 W5M8W5 PTHR13437:SF2 NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1 NUCLEOPORIN P58_P45 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 nuclear transport#GO:0051169;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000130.1|UniProtKB=W5LVI7 W5LVI7 PTHR46013:SF1 VASCULAR CELL ADHESION MOLECULE 1 VASCULAR CELL ADHESION MOLECULE 1 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002290.1|UniProtKB=W5M2R6 W5M2R6 PTHR11158:SF24 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING 1B phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215 transport#GO:0006810;lipid localization#GO:0010876;localization#GO:0051179;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000001938.1|UniProtKB=W5M1J4 W5M1J4 PTHR42921:SF5 ACETOACETYL-COA SYNTHETASE ACETOACETYL-COA SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;regulation of protein secretion#GO:0050708;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;positive regulation of cell communication#GO:0010647;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;regulation of signaling#GO:0023051;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532;regulation of insulin secretion#GO:0050796;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of protein secretion#GO:0050714 metabolite interconversion enzyme#PC00262;ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000004789.1|UniProtKB=W5MBJ6 W5MBJ6 PTHR11596:SF37 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000010641.1|UniProtKB=W5MXD9 W5MXD9 PTHR42985:SF25 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075 establishment of localization#GO:0051234;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;monoatomic ion transport#GO:0006811;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;lipid localization#GO:0010876;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;sodium ion transport#GO:0006814 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011419.1|UniProtKB=W5N077 W5N077 PTHR21324:SF3 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED MODULATOR OF MACROAUTOPHAGY TMEM150B cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000699.1|UniProtKB=W5LXC0 W5LXC0 PTHR11481:SF64 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;immune response#GO:0006955;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013908.1|UniProtKB=W5N936 W5N936 PTHR24028:SF254 CADHERIN-87A PROTOCADHERIN-11 X-LINKED-RELATED cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000017478.1|UniProtKB=W5NLS4 W5NLS4 PTHR33064:SF47 POL PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000109.1|UniProtKB=W5LVG1 W5LVG1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011582.1|UniProtKB=W5N0R9 W5N0R9 PTHR24113:SF12 RAN GTPASE-ACTIVATING PROTEIN 1 RAN GTPASE-ACTIVATING PROTEIN 1 binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;nucleocytoplasmic transport#GO:0006913;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000012931.1|UniProtKB=W5N5L5 W5N5L5 PTHR21583:SF8 ELYS PROTEIN PROTEIN ELYS scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015826.1|UniProtKB=W5NFS4 W5NFS4 PTHR21642:SF4 CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;circulatory system development#GO:0072359;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;vasculature development#GO:0001944;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;multicellular organismal process#GO:0032501;heart development#GO:0007507;vasculogenesis#GO:0001570;cellular process#GO:0009987 EGF receptor signaling pathway#P00018>MEKK1-5#P00553 LEPOC|Ensembl=ENSLOCG00000003072.1|UniProtKB=W5M5F1 W5M5F1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000002186.1|UniProtKB=W5M2D5 W5M2D5 PTHR15193:SF1 CD83 ANTIGEN CD83 ANTIGEN LEPOC|Ensembl=ENSLOCG00000000032.1|UniProtKB=W5LV79 W5LV79 PTHR24243:SF7 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015623.1|UniProtKB=W5NF23 W5NF23 PTHR12113:SF10 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 4 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005883.1|UniProtKB=W5MFE7 W5MFE7 PTHR10454:SF13 CASPASE CASPASE-4 cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;inflammatory response#GO:0006954;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;positive regulation of defense response#GO:0031349;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of neuron apoptotic process#GO:0043525;regulation of response to stress#GO:0080134;positive regulation of inflammatory response#GO:0050729;defense response#GO:0006952;positive regulation of apoptotic process#GO:0043065;positive regulation of response to external stimulus#GO:0032103 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;canonical inflammasome complex#GO:0061702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016632.1|UniProtKB=W5NIT6 W5NIT6 PTHR10746:SF18 50S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;post-transcriptional regulation of gene expression#GO:0010608;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of macromolecule metabolic process#GO:0060255;positive regulation of Notch signaling pathway#GO:0045747;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000014242.1|UniProtKB=W5NA80 W5NA80 PTHR18929:SF257 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A3 catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853 cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;biosynthetic process#GO:0009058;protein folding#GO:0006457;response to stimulus#GO:0050896;gene expression#GO:0010467;protein maturation#GO:0051604;cellular response to stress#GO:0033554;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell surface#GO:0009986;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000006936.1|UniProtKB=W5MJ33 W5MJ33 PTHR10125:SF18 P2X PURINOCEPTOR P2X PURINOCEPTOR 4 excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000018157.1|UniProtKB=W5NNP9 W5NNP9 PTHR22902:SF53 SESQUIPEDALIAN SESQUIPEDALIAN transport#GO:0006810;intracellular transport#GO:0046907;metabolic process#GO:0008152;endosome organization#GO:0007032;vesicle organization#GO:0016050;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;retrograde transport, endosome to Golgi#GO:0042147;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;cytosolic transport#GO:0016482 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003840.1|UniProtKB=W5M878 W5M878 PTHR46255:SF1 SHORT STATURE HOMEOBOX SHORT STATURE HOMEOBOX PROTEIN 2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003846.1|UniProtKB=W5M895 W5M895 PTHR21576:SF2 UNCHARACTERIZED NODULIN-LIKE PROTEIN RRP12-LIKE PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016520.1|UniProtKB=W5NIF0 W5NIF0 PTHR11347:SF111 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP AND CAMP-INHIBITED CGMP 3',5'-CYCLIC PHOSPHODIESTERASE 10A phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004903.1|UniProtKB=W5MBY5 W5MBY5 PTHR11849:SF188 ETS PROTEIN C-ETS-2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000001162.1|UniProtKB=W5LYU9 W5LYU9 PTHR34488:SF1 SI:CH211-245H14.1-RELATED SI:CH211-245H14.1-RELATED LEPOC|Ensembl=ENSLOCG00000004519.1|UniProtKB=W5MAJ5 W5MAJ5 PTHR21462:SF2 CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR CD200 RECEPTOR 1A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;signaling receptor complex#GO:0043235;external side of plasma membrane#GO:0009897 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001664.1|UniProtKB=W5M0L0 W5M0L0 PTHR24103:SF686 E3 UBIQUITIN-PROTEIN LIGASE TRIM B30.2_SPRY DOMAIN-CONTAINING PROTEIN ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000000683.1|UniProtKB=W5LXA2 W5LXA2 PTHR24034:SF96 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 2 extracellular structure organization#GO:0043062;supramolecular fiber organization#GO:0097435;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;extracellular matrix assembly#GO:0085029 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000011057.1|UniProtKB=W5MYX1 W5MYX1 PTHR22957:SF462 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 22B enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001026.1|UniProtKB=W5LYE5 W5LYE5 PTHR46139:SF2 ALKALINE CERAMIDASE ALKALINE CERAMIDASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;alcohol biosynthetic process#GO:0046165;lipid catabolic process#GO:0016042;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;ceramide metabolic process#GO:0006672;sphingoid biosynthetic process#GO:0046520 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000004491.1|UniProtKB=W5MAJ4 W5MAJ4 PTHR13402:SF11 RGPR-RELATED PROTEIN TRANSPORT PROTEIN SEC16B vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134 LEPOC|Ensembl=ENSLOCG00000015378.1|UniProtKB=W5NE63 W5NE63 PTHR23318:SF18 ATP SYNTHASE GAMMA-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3B phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of response to stress#GO:0080134;DNA damage response#GO:0006974;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of DNA metabolic process#GO:0051052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000003755.1|UniProtKB=W5M7Z5 W5M7Z5 PTHR11216:SF69 EH DOMAIN EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15-LIKE 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 plasma membrane#GO:0005886;cytoplasm#GO:0005737;clathrin coat#GO:0030118;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007145.1|UniProtKB=W5MJV8 W5MJV8 PTHR24353:SF24 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKG#P00567 LEPOC|Ensembl=ENSLOCG00000006057.1|UniProtKB=W5MG06 W5MG06 PTHR11937:SF445 ACTIN ACTIN, AORTIC SMOOTH MUSCLE structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944 LEPOC|Ensembl=ENSLOCG00000011694.1|UniProtKB=W5N170 W5N170 PTHR24025:SF16 DESMOGLEIN FAMILY MEMBER FAT ATYPICAL CADHERIN 2 calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000006485.1|UniProtKB=W5MHI3 W5MHI3 PTHR45854:SF5 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1-LIKE enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000004790.1|UniProtKB=W5MBK5 W5MBK5 PTHR12280:SF42 PANTOTHENATE KINASE 4'-PHOSPHOPANTETHEINE PHOSPHATASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 LEPOC|Ensembl=ENSLOCG00000006469.1|UniProtKB=W5MHF7 W5MHF7 MED15 PTHR31804:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015906.1|UniProtKB=W5NG26 W5NG26 PTHR10816:SF18 MYELIN TRANSCRIPTION FACTOR 1-RELATED INTERFERON REGULATORY FACTOR 2-BINDING PROTEIN 2 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003390.1|UniProtKB=W5M6K4 W5M6K4 PTHR14330:SF2 A-KINASE-INTERACTING PROTEIN 1 A-KINASE-INTERACTING PROTEIN 1 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015809.1|UniProtKB=W5NFQ1 W5NFQ1 PTHR24240:SF167 OPSIN NOVOPSIN-7 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular response to radiation#GO:0071478;signaling#GO:0023052;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signal transduction#GO:0007165;response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000536.1|UniProtKB=W5LWX7 W5LWX7 PTHR15286:SF11 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006298.1|UniProtKB=W5MGW9 W5MGW9 PTHR47385:SF18 CALPONIN TRANSGELIN actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000018185.1|UniProtKB=W5NNS7 W5NNS7 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002234.1|UniProtKB=W5M2I9 W5M2I9 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011725.1|UniProtKB=W5N1A5 W5N1A5 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 protease#PC00190;aspartic protease#PC00053 LEPOC|Ensembl=ENSLOCG00000008287.1|UniProtKB=W5MNV3 W5MNV3 PTHR19331:SF477 SCAVENGER RECEPTOR DOMAIN-CONTAINING T-CELL DIFFERENTIATION ANTIGEN CD6 cargo receptor activity#GO:0038024 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015346.1|UniProtKB=W5NE26 W5NE26 PTHR24028:SF40 CADHERIN-87A PROTOCADHERIN-19 cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000008683.1|UniProtKB=W5MQB8 W5MQB8 PTHR12203:SF21 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009916.1|UniProtKB=W5MUR1 W5MUR1 PTHR24403:SF100 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 518B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017576.1|UniProtKB=W5NM22 W5NM22 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006136.1|UniProtKB=W5MGA5 W5MGA5 PTHR23267:SF486 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14_DELTA VARIABLE 4 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000116.1|UniProtKB=W5LVH3 W5LVH3 GPR88 PTHR24246:SF48 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR G PROTEIN-COUPLED RECEPTOR 88 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012129.1|UniProtKB=W5N2R0 W5N2R0 PTHR24328:SF8 HOMEOBOX PROTEIN MOX HOMEOBOX PROTEIN MOX-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013054.1|UniProtKB=W5N616 W5N616 PTHR15074:SF7 METHYL-CPG-BINDING PROTEIN METHYL-CPG-BINDING DOMAIN PROTEIN 4 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005334.1|UniProtKB=W5MDG9 W5MDG9 PTHR12369:SF22 CHONDROITIN SYNTHASE CHONDROITIN POLYMERIZING FACTOR, NON-CATALYTIC SUBUNIT protein complex scaffold activity#GO:0140378;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;structural molecule activity#GO:0005198;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194 primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000001633.1|UniProtKB=W5M0H9 W5M0H9 PTHR11804:SF79 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED MITOCHONDRIAL INTERMEDIATE PEPTIDASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000008855.1|UniProtKB=W5MQW4 W5MQW4 PTHR12234:SF0 FORMIMINOTRANSFERASE-CYCLODEAMINASE FORMIMIDOYLTRANSFERASE-CYCLODEAMINASE lyase activity#GO:0016829;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010623.1|UniProtKB=W5MXA1 W5MXA1 PTHR12137:SF2 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 10 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000017495.1|UniProtKB=W5NLU1 W5NLU1 PTHR14491:SF8 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHD LEPOC|Ensembl=ENSLOCG00000013733.1|UniProtKB=W5N8H8 W5N8H8 PTHR14416:SF2 PROTEIN NJMU-R1 PROTEIN NJMU-R1 Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004717.1|UniProtKB=W5MB90 W5MB90 ASTN2 PTHR16592:SF10 ASTROTACTIN-1-LIKE ASTROTACTIN-2 cellular process#GO:0009987;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell migration#GO:0016477;developmental process#GO:0032502;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;neuron migration#GO:0001764;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cell motility#GO:0048870;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 LEPOC|Ensembl=ENSLOCG00000008877.1|UniProtKB=W5MQZ9 W5MQZ9 PTHR13703:SF23 SMAD SMAD FAMILY MEMBER 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;cellular response to growth factor stimulus#GO:0071363;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to transforming growth factor beta#GO:0071559;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292;Wnt signaling pathway#P00057>Smad4#P01455 LEPOC|Ensembl=ENSLOCG00000005217.1|UniProtKB=W5MD25 W5MD25 PTHR48069:SF6 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265 tetrahydrofolate metabolic process#GO:0046653;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948 LEPOC|Ensembl=ENSLOCG00000010155.1|UniProtKB=W5MVM6 W5MVM6 PTHR14399:SF3 P53-INDUCED PROTEIN RELATED TRANSMEMBRANE PROTEIN 47 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 LEPOC|Ensembl=ENSLOCG00000012962.1|UniProtKB=W5N5Q5 W5N5Q5 PTHR24099:SF6 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 2 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010395.1|UniProtKB=W5MWI2 W5MWI2 PTHR21252:SF2 TB1 PROTEIN-RELATED MITOCHONDRIAL OUTER MEMBRANE PROTEIN SLC25A46 anatomical structure development#GO:0048856;organelle fission#GO:0048285;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;mitochondrial fission#GO:0000266;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;mitochondrion organization#GO:0007005;axon development#GO:0061564;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987 organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000000320.1|UniProtKB=W5LW39 W5LW39 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009431.1|UniProtKB=W5MT12 W5MT12 PTHR13865:SF26 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 intracellular protein localization#GO:0008104;system process#GO:0003008;multicellular organismal-level homeostasis#GO:0048871;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell-cell junction organization#GO:0045216;endothelial cell differentiation#GO:0045446;developmental process#GO:0032502;biological regulation#GO:0065007;blood circulation#GO:0008015;epithelium development#GO:0060429;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;tissue development#GO:0009888;cellular process#GO:0009987;macromolecule localization#GO:0033036;cell-cell adhesion#GO:0098609;tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;localization#GO:0051179;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;protein localization to cell junction#GO:1902414;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;homeostatic process#GO:0042592;cell development#GO:0048468;cell differentiation#GO:0030154;cell junction organization#GO:0034330;cellular component organization#GO:0016043 tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000018096.1|UniProtKB=W5NNI8 W5NNI8 PTHR21255:SF55 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 4 protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001500.1|UniProtKB=W5M015 W5M015 PTHR23159:SF14 CENTROSOMAL PROTEIN 2 TESTIS-SPECIFIC GENE 10 PROTEIN centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;centriole replication#GO:0007099;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000007175.1|UniProtKB=W5MJY1 W5MJY1 PTHR23420:SF0 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;purine-containing compound metabolic process#GO:0072521;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017175.1|UniProtKB=W5NKR8 W5NKR8 PTHR24115:SF194 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF6 hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000012425.1|UniProtKB=W5N3T6 W5N3T6 PTHR14340:SF4 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 LEPOC|Ensembl=ENSLOCG00000001249.1|UniProtKB=W5LZ61 W5LZ61 PTHR24286:SF177 CYTOCHROME P450 26 CYTOCHROME P450 26B1 catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;central nervous system development#GO:0007417;regulation of hormone levels#GO:0010817;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;regulation of biological quality#GO:0065008;system development#GO:0048731;isoprenoid metabolic process#GO:0006720;anatomical structure development#GO:0048856;terpenoid metabolic process#GO:0006721;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;monocarboxylic acid catabolic process#GO:0072329;hormone metabolic process#GO:0042445;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;diterpenoid metabolic process#GO:0016101;multicellular organism development#GO:0007275;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;developmental process#GO:0032502;metabolic process#GO:0008152 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000010305.1|UniProtKB=W5MW85 W5MW85 PTHR23113:SF199 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 1 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 Ras Pathway#P04393>RalGDS#P04551 LEPOC|Ensembl=ENSLOCG00000009225.1|UniProtKB=W5MSB4 W5MSB4 PTHR45622:SF11 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC6-RELATED catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007818.1|UniProtKB=W5MM81 W5MM81 PTHR10628:SF25 SIALIDASE SIALIDASE-1 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 oligosaccharide metabolic process#GO:0009311;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;ceramide metabolic process#GO:0006672;carbohydrate catabolic process#GO:0016052;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;membrane#GO:0016020;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010781.1|UniProtKB=W5MXV8 W5MXV8 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 isomerase#PC00135 LEPOC|Ensembl=ENSLOCG00000013567.1|UniProtKB=W5N7W7 W5N7W7 PTHR11551:SF7 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 4 protein binding#GO:0005515;growth factor binding#GO:0019838;binding#GO:0005488 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012726.1|UniProtKB=W5N4V1 W5N4V1 PTHR16011:SF0 IFT57/HIPPI INTRAFLAGELLAR TRANSPORT PROTEIN 57 HOMOLOG cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;cilium assembly#GO:0060271;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111 intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;microtubule organizing center#GO:0005815 structural protein#PC00211 Huntington disease#P00029>Hip-12#P00763;Huntington disease#P00029>Hippi#P00794 LEPOC|Ensembl=ENSLOCG00000012669.1|UniProtKB=W5N4N0 W5N4N0 PTHR24103:SF611 E3 UBIQUITIN-PROTEIN LIGASE TRIM BBOX AND DUF4200 DOMAIN-CONTAINING PROTEIN-RELATED acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003523.1|UniProtKB=W5M718 W5M718 PTHR19269:SF40 TROPOMYOSIN TROPOMYOSIN 4 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;system process#GO:0003008;cellular component organization or biogenesis#GO:0071840;muscle contraction#GO:0006936;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000000178.1|UniProtKB=W5LVP1 W5LVP1 PTHR11866:SF5 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER THROMBOXANE A2 RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;positive regulation of blood pressure#GO:0045777;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of biological quality#GO:0065008;cell communication#GO:0007154;inflammatory response#GO:0006954;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of blood pressure#GO:0008217;response to stress#GO:0006950;system process#GO:0003008;defense response#GO:0006952;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of system process#GO:0044057;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of anatomical structure size#GO:0090066 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002605.1|UniProtKB=W5M3X6 W5M3X6 PTHR46902:SF1 DOMON DOMAIN-CONTAINING PROTEIN FRRS1L DOMON DOMAIN-CONTAINING PROTEIN FRRS1L regulation of biological quality#GO:0065008;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000003588.1|UniProtKB=W5M7A2 W5M7A2 PTHR11783:SF371 SULFOTRANSFERASE SULT SULFOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015970.1|UniProtKB=W5NGA4 W5NGA4 PTHR24348:SF73 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;neuron development#GO:0048666;neuron projection extension#GO:1990138;axonogenesis#GO:0007409;developmental growth involved in morphogenesis#GO:0060560;process utilizing autophagic mechanism#GO:0061919;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axon extension#GO:0048675;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular component assembly#GO:0022607;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;neuron projection development#GO:0031175;response to stress#GO:0006950;cell projection morphogenesis#GO:0048858;autophagosome assembly#GO:0000045;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell growth#GO:0016049;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;metabolic process#GO:0008152;developmental cell growth#GO:0048588;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;system development#GO:0048731;vacuole organization#GO:0007033;anatomical structure development#GO:0048856;organelle assembly#GO:0070925;biological regulation#GO:0065007;macroautophagy#GO:0016236;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;response to nutrient levels#GO:0031667;reticulophagy#GO:0061709;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of catabolic process#GO:0009894;neurogenesis#GO:0022008;mitophagy#GO:0000423;cellular developmental process#GO:0048869;developmental growth#GO:0048589;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;autophagy of mitochondrion#GO:0000422 intracellular organelle#GO:0043229;phagophore assembly site#GO:0000407;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002501.1|UniProtKB=W5M3I0 W5M3I0 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000668.1|UniProtKB=W5LX81 W5LX81 PTHR14972:SF7 AGAP011572-PA PROTEIN FAM117A LEPOC|Ensembl=ENSLOCG00000005100.1|UniProtKB=W5MCN1 W5MCN1 PTHR11486:SF74 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 19 protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;fibroblast growth factor receptor binding#GO:0005104;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545 positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;response to fibroblast growth factor#GO:0071774;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;nervous system development#GO:0007399;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363 extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003073.1|UniProtKB=W5M5F9 W5M5F9 PTHR10544:SF0 60S RIBOSOMAL PROTEIN L28 LARGE RIBOSOMAL SUBUNIT PROTEIN EL28 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000007998.1|UniProtKB=W5MMV3 W5MMV3 PTHR10913:SF44 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 5 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000013971.1|UniProtKB=W5N9B1 W5N9B1 PTHR12692:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT TUSC3 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;protein metabolic process#GO:0019538;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;establishment of localization#GO:0051234;magnesium ion transport#GO:0015693;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;transport#GO:0006810;biosynthetic process#GO:0009058;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000003128.1|UniProtKB=W5M5Q9 W5M5Q9 PTHR10766:SF55 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2 cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;cellular process#GO:0009987;localization within membrane#GO:0051668 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008899.1|UniProtKB=W5MR40 W5MR40 PTHR11616:SF38 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT DOPAMINE TRANSPORTER metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;amino acid transport#GO:0006865 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>DAT#P00065;Parkinson disease#P00049>DAT#P01228;Dopamine receptor mediated signaling pathway#P05912>DAT#P05962;Parkinson disease#P00049>DAT#G01547 LEPOC|Ensembl=ENSLOCG00000011246.1|UniProtKB=W5MZM3 W5MZM3 PTHR11255:SF32 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE BETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;neutral lipid metabolic process#GO:0006638;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003405.1|UniProtKB=W5M6N4 W5M6N4 PTHR14453:SF70 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP9 transcription corepressor activity#GO:0003714;transferase activity#GO:0016740;ubiquitin-like protein ligase binding#GO:0044389;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;glycosyltransferase activity#GO:0016757;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;pentosyltransferase activity#GO:0016763;binding#GO:0005488;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;protein binding#GO:0005515 positive regulation of signaling#GO:0023056;positive regulation of cytokine-mediated signaling pathway#GO:0001961;regulation of signaling#GO:0023051;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of response to external stimulus#GO:0032103;regulation of cytokine-mediated signaling pathway#GO:0001959;regulation of response to external stimulus#GO:0032101;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of response to cytokine stimulus#GO:0060759;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;positive regulation of signal transduction#GO:0009967;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of response to biotic stimulus#GO:0002833;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of innate immune response#GO:0045089 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012073.1|UniProtKB=W5N2J4 W5N2J4 PTHR11860:SF111 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010959.1|UniProtKB=W5MYI5 W5MYI5 PTHR24182:SF13 ANKYRIN REPEAT AND SOCS BOX CONTAINING 4 LD18443P LEPOC|Ensembl=ENSLOCG00000015250.1|UniProtKB=W5NDQ7 W5NDQ7 PTHR12064:SF26 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM4 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;magnesium ion transmembrane transporter activity#GO:0015095;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 inorganic ion homeostasis#GO:0098771;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;magnesium ion transport#GO:0015693;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion homeostasis#GO:0050801;metal ion transport#GO:0030001;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009478.1|UniProtKB=W5MT59 W5MT59 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000018092.1|UniProtKB=W5NNI4 W5NNI4 PTHR16100:SF5 PHOSPHOINOSITIDE-INTERACTING PROTEIN FAMILY MEMBER TRANSMEMBRANE PROTEIN 100 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of system process#GO:0044057;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000009937.1|UniProtKB=W5MUU7 W5MUU7 PTHR45783:SF7 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 1 cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 LEPOC|Ensembl=ENSLOCG00000006826.1|UniProtKB=W5MIP5 W5MIP5 PTHR45879:SF2 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;p38 MAPK pathway#P05918>ATF1#P06019 LEPOC|Ensembl=ENSLOCG00000004292.1|UniProtKB=W5M9R7 W5M9R7 PTHR10218:SF130 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-12 hydrolase activity#GO:0016787;protein binding#GO:0005515;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;G protein-coupled receptor binding#GO:0001664 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 apical part of cell#GO:0045177;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;brush border#GO:0005903;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;brush border membrane#GO:0031526;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;cell projection membrane#GO:0031253;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;apical plasma membrane#GO:0016324;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000005045.1|UniProtKB=W5MCG1 W5MCG1 PTHR36876:SF2 UROTENSIN-2B UROTENSIN 2 DOMAIN CONTAINING PRECURSOR LEPOC|Ensembl=ENSLOCG00000003051.1|UniProtKB=W5M5D2 W5M5D2 ENY2 PTHR12514:SF1 ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR TRANSCRIPTION AND MRNA EXPORT FACTOR ENY2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nitrogen compound transport#GO:0071705;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;regulation of cellular process#GO:0050794;RNA transport#GO:0050658;RNA localization#GO:0006403;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound transport#GO:0015931;nuclear export#GO:0051168;regulation of RNA metabolic process#GO:0051252;nuclear transport#GO:0051169;regulation of DNA-templated transcription#GO:0006355;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;gene expression#GO:0010467;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;metabolic process#GO:0008152;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406 transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;SAGA complex#GO:0000124;DUBm complex#GO:0071819;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013781.1|UniProtKB=W5N8N8 W5N8N8 PTHR10410:SF51 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED BRCA1_BRCA2-CONTAINING COMPLEX SUBUNIT 3 catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000011453.1|UniProtKB=W5N0B0 W5N0B0 PTHR16131:SF2 LIGAND-DEPENDENT NUCLEAR RECEPTOR-INTERACTING FACTOR 1 LIGAND-DEPENDENT NUCLEAR RECEPTOR-INTERACTING FACTOR 1 LEPOC|Ensembl=ENSLOCG00000010370.1|UniProtKB=W5MWF1 W5MWF1 PTHR11494:SF10 CYTOTOXIC T-LYMPHOCYTE PROTEIN CYTOTOXIC T-LYMPHOCYTE PROTEIN 4 response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;immune system process#GO:0002376;regulation of immune response#GO:0050776;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014373.1|UniProtKB=W5NAP0 W5NAP0 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001149.1|UniProtKB=W5LYV1 W5LYV1 PTHR10527:SF6 IMPORTIN BETA IMPORTIN-4 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002206.1|UniProtKB=W5M2G6 W5M2G6 PTHR13691:SF16 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000017897.1|UniProtKB=W5NMZ1 W5NMZ1 PTHR15437:SF1 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR 2, MITOCHONDRIAL binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mitochondrial transcription#GO:0006390;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 General transcription regulation#P00023>TTF2#P00661;Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 LEPOC|Ensembl=ENSLOCG00000010469.1|UniProtKB=W5MWS1 W5MWS1 PTHR12458:SF7 ORF PROTEIN PROTEIN CFAP20DC LEPOC|Ensembl=ENSLOCG00000008059.1|UniProtKB=W5MN40 W5MN40 PTHR13593:SF131 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 LEPOC|Ensembl=ENSLOCG00000016122.1|UniProtKB=W5NGV5 W5NGV5 PTHR19332:SF1 PEROXISOMAL MEMBRANE PROTEIN PEX13 PEROXISOMAL MEMBRANE PROTEIN PEX13 cellular component organization#GO:0016043;protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031;peroxisomal transport#GO:0043574;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;organelle organization#GO:0006996;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;protein-containing complex#GO:0032991;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;transporter complex#GO:1990351;intracellular organelle#GO:0043229 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005632.1|UniProtKB=W5MEI7 W5MEI7 PTHR46126:SF1 DYNACTIN SUBUNIT 5 DYNACTIN SUBUNIT 5 actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000012106.1|UniProtKB=W5N2P7 W5N2P7 PTHR12515:SF8 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED PROTEIN SMAUG HOMOLOG 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000016956.1|UniProtKB=W5NK05 W5NK05 PTHR46877:SF9 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 7 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773 neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005159.1|UniProtKB=W5MCV2 W5MCV2 PTHR15710:SF21 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF126 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to topologically incorrect protein#GO:0035966;primary metabolic process#GO:0044238;response to misfolded protein#GO:0051788;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;cellular response to topologically incorrect protein#GO:0035967;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;cellular response to misfolded protein#GO:0071218 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014732.1|UniProtKB=W5NBX8 W5NBX8 PTHR46520:SF1 SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;regulation of lipid metabolic process#GO:0019216;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000008937.1|UniProtKB=W5MR76 W5MR76 PTHR11829:SF340 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN H1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000004544.1|UniProtKB=W5MAP3 W5MAP3 PTHR15606:SF4 DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 8 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016245.1|UniProtKB=W5NHC2 W5NHC2 PTHR13353:SF5 TRANSMEMBRANE PROTEIN 19 TRANSMEMBRANE PROTEIN 19 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003581.1|UniProtKB=W5M788 W5M788 PTHR46115:SF1 THIOREDOXIN-LIKE PROTEIN 1 THIOREDOXIN-LIKE PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122 LEPOC|Ensembl=ENSLOCG00000009293.1|UniProtKB=W5MSH9 W5MSH9 PTHR22763:SF167 RING ZINC FINGER PROTEIN RING FINGER PROTEIN 145 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013690.1|UniProtKB=W5N8B7 W5N8B7 PTHR43048:SF3 METHYLMALONYL-COA EPIMERASE METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;isomerase activity#GO:0016853 purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086 isomerase#PC00135;epimerase/racemase#PC00096 Methylmalonyl pathway#P02755>Methylmalonyl-CoA epimerase#P03032 LEPOC|Ensembl=ENSLOCG00000017526.1|UniProtKB=W5NLX2 W5NLX2 PTHR24232:SF20 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 1 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of coagulation#GO:0050818;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of hemostasis#GO:1900046;regulation of response to wounding#GO:1903034;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;signaling#GO:0023052;regulation of wound healing#GO:0061041;response to stimulus#GO:0050896;regulation of blood coagulation#GO:0030193;regulation of body fluid levels#GO:0050878;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological quality#GO:0065008;cell communication#GO:0007154;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of coagulation#GO:0050820;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Angiogenesis#P00005>PAR#P00192;Blood coagulation#P00011>PAR-1#P00404 LEPOC|Ensembl=ENSLOCG00000002260.1|UniProtKB=W5M2U2 W5M2U2 PTHR13167:SF24 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 2 gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 detection of mechanical stimulus#GO:0050982;cellular response to abiotic stimulus#GO:0071214;regulation of membrane potential#GO:0042391;regulation of biological quality#GO:0065008;response to external stimulus#GO:0009605;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to mechanical stimulus#GO:0009612;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000002949.1|UniProtKB=W5M517 W5M517 PTHR16208:SF4 MICROTUBULE-ASSOCIATED PROTEIN/SYNTAPHILIN SYNTABULIN cell junction organization#GO:0034330;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;localization#GO:0051179;anatomical structure development#GO:0048856;cellular localization#GO:0051641;system development#GO:0048731;axonal transport#GO:0098930;organelle localization#GO:0051640;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;synapse organization#GO:0050808;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;nervous system development#GO:0007399;axo-dendritic transport#GO:0008088;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;developmental process#GO:0032502;transport#GO:0006810 cytoplasmic microtubule#GO:0005881;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000007816.1|UniProtKB=W5MM84 W5MM84 PTHR11679:SF33 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 3 binding#GO:0005488;SNARE binding#GO:0000149;syntaxin binding#GO:0019905;protein binding#GO:0005515 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;vesicle localization#GO:0051648;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;calcium-ion regulated exocytosis#GO:0017156;intracellular transport#GO:0046907;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;vesicle-mediated transport#GO:0016192;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;synaptic signaling#GO:0099536;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;intracellular protein transport#GO:0006886;regulated exocytosis#GO:0045055;signaling#GO:0023052;export from cell#GO:0140352;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;secretion by cell#GO:0032940;protein transport#GO:0015031;cellular localization#GO:0051641 endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000009941.1|UniProtKB=W5MUV2 W5MUV2 PTHR46221:SF13 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000011234.1|UniProtKB=W5MZJ7 W5MZJ7 PTHR46766:SF1 GLUTAMINE-RICH PROTEIN 2 GLUTAMINE RICH 2 LEPOC|Ensembl=ENSLOCG00000001431.1|UniProtKB=W5LZS2 W5LZS2 PTHR10920:SF18 RIBOSOMAL RNA METHYLTRANSFERASE RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 rRNA methylation#GO:0031167;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;methylation#GO:0032259;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;rRNA modification#GO:0000154;protein-containing complex assembly#GO:0065003;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein-RNA complex assembly#GO:0022618;RNA methylation#GO:0001510;rRNA processing#GO:0006364;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000001538.1|UniProtKB=W5M060 W5M060 PTHR46533:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12 LEPOC|Ensembl=ENSLOCG00000013132.1|UniProtKB=W5N6D1 W5N6D1 PTHR11792:SF20 ARRESTIN BETA-ARRESTIN-2 signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 negative regulation of cell communication#GO:0010648;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;nervous system process#GO:0050877;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;endocytosis#GO:0006897;regulation of biological process#GO:0050789;sensory perception of pain#GO:0019233;negative regulation of biological process#GO:0048519;import into cell#GO:0098657;regulation of MAPK cascade#GO:0043408;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;receptor internalization#GO:0031623;localization#GO:0051179;sensory perception#GO:0007600;modulation of chemical synaptic transmission#GO:0050804;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of signal transduction#GO:0009967;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;system process#GO:0003008;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;transport#GO:0006810;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>beta-ARR2#P05923;CCKR signaling map#P06959>Beta-arrestin-1/2#P07187;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723;Wnt signaling pathway#P00057>beta-arrestin#P01456;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880 LEPOC|Ensembl=ENSLOCG00000009012.1|UniProtKB=W5MRI0 W5MRI0 PTHR10060:SF15 TATD FAMILY DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE TATDN1 exonuclease activity#GO:0004527;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000000173.1|UniProtKB=W5LVN7 W5LVN7 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006045.1|UniProtKB=W5MFZ7 W5MFZ7 PTHR11699:SF228 ALDEHYDE DEHYDROGENASE-RELATED 4-TRIMETHYLAMINOBUTYRALDEHYDE DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000013539.1|UniProtKB=W5N7T8 W5N7T8 PTHR11793:SF11 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR 12 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000016281.1|UniProtKB=W5NHH7 W5NHH7 PTHR12784:SF18 STEERIN NEURON NAVIGATOR 3 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;microtubule end#GO:1990752;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080 LEPOC|Ensembl=ENSLOCG00000004603.1|UniProtKB=W5MAW0 W5MAW0 PTHR11977:SF27 VILLIN MACROPHAGE-CAPPING PROTEIN lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;actin filament binding#GO:0051015;actin binding#GO:0003779;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543 cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;nervous system development#GO:0007399;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;regulation of anatomical structure size#GO:0090066;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;central nervous system development#GO:0007417;regulation of actin filament length#GO:0030832;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;negative regulation of protein depolymerization#GO:1901880;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;multicellular organismal process#GO:0032501;regulation of actin filament polymerization#GO:0030833;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;negative regulation of protein-containing complex assembly#GO:0031333;system development#GO:0048731;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 FAS signaling pathway#P00020>Gelsolin#P00611 LEPOC|Ensembl=ENSLOCG00000009594.1|UniProtKB=W5MTL4 W5MTL4 PTHR10269:SF15 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;nervous system development#GO:0007399;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018273.1|UniProtKB=W5NP15 W5NP15 GJB4 PTHR11984:SF29 CONNEXIN GAP JUNCTION BETA-5 PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000014082.1|UniProtKB=W5N9P3 W5N9P3 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007609.1|UniProtKB=W5MLI1 W5MLI1 PTHR24255:SF18 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1S SUBCOMPONENT serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000010356.1|UniProtKB=W5MWF2 W5MWF2 PTHR10857:SF22 COPINE COPINE-3 protein binding#GO:0005515;lipid binding#GO:0008289;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;phospholipid binding#GO:0005543;receptor tyrosine kinase binding#GO:0030971 cell surface receptor signaling pathway#GO:0007166;response to metal ion#GO:0010038;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to calcium ion#GO:0051592;cellular response to chemical stimulus#GO:0070887;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000005088.1|UniProtKB=W5MCL7 W5MCL7 PTHR22776:SF105 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING 3 immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response#GO:0006955;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017894.1|UniProtKB=W5NMY8 W5NMY8 PTHR36682:SF2 RAB15 EFFECTOR PROTEIN RAB15 EFFECTOR PROTEIN LEPOC|Ensembl=ENSLOCG00000009323.1|UniProtKB=W5MSL9 W5MSL9 PTHR14690:SF10 IQ MOTIF CONTAINING WITH AAA DOMAIN 1 IQ MOTIF CONTAINING WITH AAA DOMAIN 1 LEPOC|Ensembl=ENSLOCG00000008389.1|UniProtKB=W5MP87 W5MP87 PTHR11538:SF40 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000013752.1|UniProtKB=W5N8J9 W5N8J9 PTHR15896:SF7 GOLGI PHOSPHOPROTEIN 2/GP73-RELATED PROTEIN GOLM2 LEPOC|Ensembl=ENSLOCG00000009471.1|UniProtKB=W5MT71 W5MT71 PTHR12157:SF15 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2 structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of synaptic vesicle exocytosis#GO:2000300;export from cell#GO:0140352;signaling#GO:0023052;regulation of neurotransmitter secretion#GO:0046928;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;cellular localization#GO:0051641;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;cellular component assembly#GO:0022607;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of exocytosis#GO:0017157;secretion#GO:0046903;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234 presynapse#GO:0098793;cell cortex#GO:0005938;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic membrane#GO:0097060;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;presynaptic active zone#GO:0048786 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>RIM1alpha/2alpha#P05776 LEPOC|Ensembl=ENSLOCG00000010970.1|UniProtKB=W5MYJ8 W5MYJ8 PTHR46029:SF2 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN 1 transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 LEPOC|Ensembl=ENSLOCG00000002953.1|UniProtKB=W5M538 W5M538 PTHR10837:SF23 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014054.1|UniProtKB=W5N9L4 W5N9L4 PTHR12377:SF2 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2A protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007606.1|UniProtKB=W5MLH1 W5MLH1 PTHR10460:SF2 ABL INTERACTOR FAMILY MEMBER ABL INTERACTOR 1 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neuron migration#GO:0001764;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502 organelle#GO:0043226;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;cell leading edge#GO:0031252;actin-based cell projection#GO:0098858;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004241.1|UniProtKB=W5M9N9 W5M9N9 PTHR13723:SF39 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 15 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000015984.1|UniProtKB=W5NGC2 W5NGC2 PTHR11851:SF103 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT BETA catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;endopeptidase complex#GO:1905369;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016652.1|UniProtKB=W5NIW2 W5NIW2 PTHR12381:SF11 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;positive regulation of RNA biosynthetic process#GO:1902680;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;mRNA processing#GO:0006397;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;RNA splicing#GO:0008380;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000012251.1|UniProtKB=W5N367 W5N367 PTHR12015:SF202 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 14 immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune system process#GO:0002376;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to external stimulus#GO:0009605;defense response#GO:0006952;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000006812.1|UniProtKB=W5MIP4 W5MIP4 PTHR47968:SF83 CENTROMERE PROTEIN E CENTROMERE-ASSOCIATED PROTEIN E tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 microtubule-based movement#GO:0007018;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;cell cycle#GO:0007049;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000013527.1|UniProtKB=W5N7T3 W5N7T3 PTHR13145:SF0 SSM4 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MARCHF6 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014706.1|UniProtKB=W5NBV1 W5NBV1 PTHR21483:SF18 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011048.1|UniProtKB=W5MYV3 W5MYV3 PTHR11250:SF4 TACHYKININ TACHYKININ 1 LEPOC|Ensembl=ENSLOCG00000017666.1|UniProtKB=W5NMB2 W5NMB2 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014375.1|UniProtKB=W5NAP2 W5NAP2 PTHR10953:SF162 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 1 sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein sumoylation#GO:0016925;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000013100.1|UniProtKB=W5N678 W5N678 PTHR21522:SF36 PROTON CHANNEL OTOP PROTON CHANNEL OTOP3 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;identical protein binding#GO:0042802;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;binding#GO:0005488 transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004611.1|UniProtKB=W5MAW3 W5MAW3 PTHR23349:SF48 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 24 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000017069.1|UniProtKB=W5NKD6 W5NKD6 PTHR31531:SF2 E3 UBIQUITIN-PROTEIN LIGASE E3D FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE E3D ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;cyclin binding#GO:0030332;transferase activity#GO:0016740;catalytic activity#GO:0003824 proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015348.1|UniProtKB=W5NE27 W5NE27 PTHR14064:SF3 CHONDROMODULIN-RELATED TENOMODULIN regulation of vasculature development#GO:1901342;negative regulation of cellular process#GO:0048523;regulation of angiogenesis#GO:0045765;negative regulation of angiogenesis#GO:0016525;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cell population proliferation#GO:0042127;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of cell population proliferation#GO:0008285;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000007502.1|UniProtKB=W5ML47 W5ML47 PTHR24241:SF181 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 83 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008761.1|UniProtKB=W5MQK4 W5MQK4 PTHR19143:SF272 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN-LIKE PROTEIN 1 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000009292.1|UniProtKB=W5MSH3 W5MSH3 PTHR24056:SF594 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 5 protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 neurogenesis#GO:0022008;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;vesicle localization#GO:0051648;axon development#GO:0061564;system development#GO:0048731;anatomical structure development#GO:0048856;localization#GO:0051179;organelle localization#GO:0051640;cell death#GO:0008219;programmed cell death#GO:0012501;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle transport#GO:0048489;neuron projection development#GO:0031175;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular localization#GO:0051641;neuron apoptotic process#GO:0051402;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;establishment of organelle localization#GO:0051656;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;apoptotic process#GO:0006915;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Axon guidance mediated by semaphorins#P00007>Cdk5#P00336;Dopamine receptor mediated signaling pathway#P05912>CDK5#P05951;Nicotine pharmacodynamics pathway#P06587>CDK5#P06597;PDGF signaling pathway#P00047>GSK3#P01153;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902 LEPOC|Ensembl=ENSLOCG00000013267.1|UniProtKB=W5N6U4 W5N6U4 PTHR15874:SF1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell division#GO:0051301;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070;establishment of spindle localization#GO:0051293;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;establishment of organelle localization#GO:0051656;nuclear division#GO:0000280;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;cellular localization#GO:0051641;spindle localization#GO:0051653;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000005952.1|UniProtKB=W5MFP3 W5MFP3 PTHR10037:SF192 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1H metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated sodium channel activity#GO:0005248;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;sodium channel activity#GO:0005272;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245 calcium ion transport#GO:0006816;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046;localization#GO:0051179;monoatomic cation transport#GO:0006812;positive regulation of secretion#GO:0051047;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;calcium ion import#GO:0070509;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;action potential#GO:0001508 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;neuron projection#GO:0043005 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000004072.1|UniProtKB=W5M901 W5M901 PTHR14369:SF0 SURFEIT LOCUS PROTEIN 6 SURFEIT LOCUS PROTEIN 6 binding#GO:0005488;nucleic acid binding#GO:0003676;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;molecular condensate scaffold activity#GO:0140693;RNA binding#GO:0003723 cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015587.1|UniProtKB=W5NEY2 W5NEY2 PTHR24157:SF3 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;spermatogenesis#GO:0007283;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;male gamete generation#GO:0048232;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;negative regulation of metabolic process#GO:0009892;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;gamete generation#GO:0007276;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;developmental process involved in reproduction#GO:0003006 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;P granule#GO:0043186;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004583.1|UniProtKB=W5MAT1 W5MAT1 PTHR43391:SF9 RETINOL DEHYDROGENASE-RELATED RETINOL DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000007915.1|UniProtKB=W5MMK7 W5MMK7 PTHR14057:SF44 TRANSCRIPTION FACTOR ONECUT ONE CUT DOMAIN FAMILY MEMBER cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000005862.1|UniProtKB=W5MFC0 W5MFC0 PTHR23255:SF69 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein binding#GO:0005515;kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;dorsal/ventral pattern formation#GO:0009953;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;pattern specification process#GO:0007389;response to transforming growth factor beta#GO:0071559;regionalization#GO:0003002;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular developmental process#GO:0048869;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;response to BMP#GO:0071772;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;transforming growth factor beta receptor signaling pathway#GO:0007179;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283 LEPOC|Ensembl=ENSLOCG00000003136.1|UniProtKB=W5M5R7 W5M5R7 PTHR11781:SF22 IODOTHYRONINE DEIODINASE TYPE I IODOTHYRONINE DEIODINASE metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010253.1|UniProtKB=W5MVZ2 W5MVZ2 PTHR24320:SF264 RETINOL DEHYDROGENASE POLYPRENOL DEHYDROGENASE alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000013718.1|UniProtKB=W5N8F5 W5N8F5 PTHR35345:SF1 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 2 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 2 chromosome localization#GO:0050000;homologous chromosome pairing at meiosis#GO:0007129;cellular process#GO:0009987;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;reproductive process#GO:0022414;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;telomere localization#GO:0034397;cell cycle#GO:0007049;organelle fission#GO:0048285;localization#GO:0051179;sexual reproduction#GO:0019953;nuclear division#GO:0000280;organelle localization#GO:0051640;telomere tethering at nuclear periphery#GO:0034398;meiosis I cell cycle process#GO:0061982 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;membrane#GO:0016020;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 LEPOC|Ensembl=ENSLOCG00000003342.1|UniProtKB=W5M6E9 W5M6E9 PTHR21595:SF3 PATRONIN CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 negative regulation of cytoskeleton organization#GO:0051494;microtubule cytoskeleton organization#GO:0000226;negative regulation of protein-containing complex disassembly#GO:0043242;supramolecular fiber organization#GO:0097435;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;cytoplasmic microtubule organization#GO:0031122;negative regulation of biological process#GO:0048519;negative regulation of organelle organization#GO:0010639;cellular component organization#GO:0016043;negative regulation of cellular component organization#GO:0051129;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;negative regulation of cellular process#GO:0048523;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein depolymerization#GO:1901880;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 LEPOC|Ensembl=ENSLOCG00000016589.1|UniProtKB=W5NIN2 W5NIN2 PTHR45746:SF7 LP21163P REGULATOR OF G PROTEIN SIGNALING 7 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 LEPOC|Ensembl=ENSLOCG00000008224.1|UniProtKB=W5MNN4 W5MNN4 PTHR15592:SF16 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000015252.1|UniProtKB=W5NDQ9 W5NDQ9 PTHR12223:SF20 VESICULAR MANNOSE-BINDING LECTIN VIP36-LIKE PROTEIN binding#GO:0005488;small molecule binding#GO:0036094;carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005752.1|UniProtKB=W5MF05 W5MF05 PTHR24377:SF964 IP01015P-RELATED ZINC FINGER PROTEIN 408 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011067.1|UniProtKB=W5MYY1 W5MYY1 PTHR45850:SF2 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-5 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009709.1|UniProtKB=W5MTZ6 W5MTZ6 PTHR15746:SF20 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 2 secretion by cell#GO:0032940;exocytosis#GO:0006887;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;regulated exocytosis#GO:0045055;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000009133.1|UniProtKB=W5MRX4 W5MRX4 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740 proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;aminoglycan biosynthetic process#GO:0006023;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015329.1|UniProtKB=W5NE03 W5NE03 PTHR15286:SF9 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 8 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015549.1|UniProtKB=W5NET4 W5NET4 PTHR10827:SF76 RETICULOCALBIN CALUMENIN binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000008901.1|UniProtKB=W5MR27 W5MR27 PTHR45997:SF4 DNA LIGASE 4 DNA LIGASE 4 heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ligase activity#GO:0016874;ribonucleotide binding#GO:0032553;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;nucleotide binding#GO:0000166;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA binding#GO:0003677;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleic acid binding#GO:0003676 DNA repair#GO:0006281;DNA damage response#GO:0006974;developmental process#GO:0032502;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;multicellular organismal process#GO:0032501;somatic cell DNA recombination#GO:0016444;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;anatomical structure development#GO:0048856;system development#GO:0048731;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;multicellular organism development#GO:0007275;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;somatic recombination of immunoglobulin gene segments#GO:0016447;gene expression#GO:0010467;nucleotide-excision repair#GO:0006289;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;cellular response to stress#GO:0033554;immune system development#GO:0002520;V(D)J recombination#GO:0033151;production of molecular mediator of immune response#GO:0002440;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;DNA repair complex#GO:1990391;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006612.1|UniProtKB=W5MI04 W5MI04 PTHR46377:SF1 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of JNK cascade#GO:0046328;regulation of intracellular signal transduction#GO:1902531;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000016033.1|UniProtKB=W5NGI9 W5NGI9 PTHR31258:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 3 KERATINOCYTE-ASSOCIATED PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000017283.1|UniProtKB=W5NL70 W5NL70 PTHR19134:SF209 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE KAPPA catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000012846.1|UniProtKB=W5N5A0 W5N5A0 PTHR28573:SF1 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 SKA COMPLEX SUBUNIT 1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;regulation of microtubule polymerization or depolymerization#GO:0031110;chromosome segregation#GO:0007059;regulation of microtubule-based process#GO:0032886 spindle microtubule#GO:0005876;microtubule#GO:0005874;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitotic spindle#GO:0072686;chromosome#GO:0005694;kinetochore#GO:0000776;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;outer kinetochore#GO:0000940;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;spindle#GO:0005819;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000012708.1|UniProtKB=W5N4S3 W5N4S3 PTHR11958:SF109 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 3 neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;sodium:dicarboxylate symporter activity#GO:0017153 localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;L-glutamate import#GO:0051938;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;establishment of localization#GO:0051234;transport#GO:0006810;carboxylic acid transport#GO:0046942;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;amino acid transport#GO:0006865;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 LEPOC|Ensembl=ENSLOCG00000014566.1|UniProtKB=W5NBC0 W5NBC0 PTHR21818:SF0 BC025462 PROTEIN FANCONI ANEMIA GROUP I PROTEIN regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;biological regulation#GO:0065007;DNA damage response#GO:0006974;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;DNA repair complex#GO:1990391;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000014383.1|UniProtKB=W5NAQ1 W5NAQ1 PTHR11472:SF1 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;damaged DNA binding#GO:0003684;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011758.1|UniProtKB=W5N1E8 W5N1E8 PTHR11860:SF111 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001596.1|UniProtKB=W5M0C6 W5M0C6 PTHR10201:SF298 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-28 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000011555.1|UniProtKB=W5N0U1 W5N0U1 PTHR45628:SF9 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1S channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 transport#GO:0006810;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;import into cell#GO:0098657;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;calcium channel complex#GO:0034704;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241 5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812 LEPOC|Ensembl=ENSLOCG00000002472.1|UniProtKB=W5M3E3 W5M3E3 PTHR12271:SF34 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE 7 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000000576.1|UniProtKB=W5LWY0 W5LWY0 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004381.1|UniProtKB=W5MA22 W5MA22 PTHR15381:SF1 CHONDROITIN SULFATE PROTEOGLYCAN 5 -RELATED CHONDROITIN SULFATE PROTEOGLYCAN 5 neuron development#GO:0048666;generation of neurons#GO:0048699;cellular response to stress#GO:0033554;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;gliogenesis#GO:0042063;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;regeneration#GO:0031099;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;response to stress#GO:0006950;system development#GO:0048731;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;response to wounding#GO:0009611;axon development#GO:0061564 postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000005342.1|UniProtKB=W5MDI1 W5MDI1 PTHR11819:SF171 SOLUTE CARRIER FAMILY 5 SODIUM_MYO-INOSITOL COTRANSPORTER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000007886.1|UniProtKB=W5MMG7 W5MMG7 PTHR12390:SF0 UROPORPHYRINOGEN III SYNTHASE UROPORPHYRINOGEN-III SYNTHASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 porphyrin-containing compound metabolic process#GO:0006778;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 Heme biosynthesis#P02746>Uroporphyrinogen-III synthase#P02974 LEPOC|Ensembl=ENSLOCG00000017164.1|UniProtKB=W5NKQ7 W5NKQ7 PTHR19282:SF377 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004844.1|UniProtKB=W5MBT4 W5MBT4 PTHR23220:SF3 INTEGRIN ALPHA INTEGRIN ALPHA-5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000006079.1|UniProtKB=W5MG36 W5MG36 PTHR18945:SF34 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT DELTA ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;chloride channel activity#GO:0005254;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230 trans-synaptic signaling#GO:0099537;transmembrane transport#GO:0055085;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000006250.1|UniProtKB=W5MGN5 W5MGN5 PTHR46096:SF5 PERFORIN-1 PERFORIN 1.7-RELATED channel activity#GO:0015267;wide pore channel activity#GO:0022829;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;leukocyte mediated cytotoxicity#GO:0001909;defense response to virus#GO:0051607;leukocyte activation#GO:0045321;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;response to virus#GO:0009615;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;cell recognition#GO:0008037;cell activation#GO:0001775;T cell mediated immunity#GO:0002456;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;response to other organism#GO:0051707;adaptive immune response#GO:0002250;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;immune response#GO:0006955;defense response#GO:0006952;cell-cell recognition#GO:0009988;response to external stimulus#GO:0009605;cell killing#GO:0001906;immune effector process#GO:0002252 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010754.1|UniProtKB=W5MXR9 W5MXR9 PTHR11849:SF195 ETS GA-BINDING PROTEIN ALPHA CHAIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000012127.1|UniProtKB=W5N2R1 W5N2R1 PTHR48013:SF15 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 Huntington disease#P00029>SEK-1#P00792;Integrin signalling pathway#P00034>MEK#P00925;Apoptosis signaling pathway#P00006>SEK1#P00266;Angiogenesis#P00005>JNKK1#P00199;EGF receptor signaling pathway#P00018>MKK4,7#P00555;FGF signaling pathway#P00021>MKK4,7#P00637;Integrin signalling pathway#P00034>Jnk#P00951;Gonadotropin-releasing hormone receptor pathway#P06664>MKK4/7#P06760;FAS signaling pathway#P00020>MKK4#P00610;Ras Pathway#P04393>MKK4/7#P04565;p38 MAPK pathway#P05918>MKK4#P06034;Toll receptor signaling pathway#P00054>MKK4#P01366;Huntington disease#P00029>MAPKK4#P00787;Oxidative stress response#P00046>MKK4#P01138;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 LEPOC|Ensembl=ENSLOCG00000009574.1|UniProtKB=W5MTJ1 W5MTJ1 PTHR11610:SF199 LIPASE PANCREATIC TRIACYLGLYCEROL LIPASE-LIKE ISOFORM X2 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000018290.1|UniProtKB=W5NP32 W5NP32 PTHR22750:SF10 G-PROTEIN COUPLED RECEPTOR CANNABINOID RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003631.1|UniProtKB=W5M7E4 W5M7E4 PTHR24006:SF899 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12A-LIKE hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013625.1|UniProtKB=W5N838 W5N838 PTHR12509:SF8 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 4 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000014848.1|UniProtKB=W5NCC5 W5NCC5 PTHR24347:SF372 SERINE/THREONINE-PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002872.1|UniProtKB=W5M4R5 W5M4R5 PTHR22426:SF1 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 LYSINE-RICH NUCLEOLAR PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000007110.1|UniProtKB=W5MJQ0 W5MJQ0 PTHR10201:SF224 MATRIX METALLOPROTEINASE MATRIX METALLOPEPTIDASE 17B peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000006935.1|UniProtKB=W5MJ28 W5MJ28 PTHR11829:SF411 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009169.1|UniProtKB=W5MS24 W5MS24 PTHR12058:SF0 ARP2/3 COMPLEX 34 KDA SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cortical actin cytoskeleton organization#GO:0030866;supramolecular fiber organization#GO:0097435;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314 actin cytoskeleton#GO:0015629;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 LEPOC|Ensembl=ENSLOCG00000016258.1|UniProtKB=W5NHE3 W5NHE3 PTHR21255:SF19 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 1 protein binding#GO:0005515;binding#GO:0005488 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000014080.1|UniProtKB=W5N9P4 W5N9P4 PTHR21397:SF2 CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED BPTF-ASSOCIATED CHROMATIN COMPLEX COMPONENT 1 SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ISWI-type complex#GO:0031010;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012333.1|UniProtKB=W5N3H0 W5N3H0 PTHR15231:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;phospholipid metabolic process#GO:0006644;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011662.1|UniProtKB=W5N127 W5N127 PTHR46605:SF3 TUMOR NECROSIS FACTOR RECEPTOR TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16 growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;death receptor activity#GO:0005035;signaling receptor activity#GO:0038023;coreceptor activity#GO:0015026 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007043.1|UniProtKB=W5MJI5 W5MJI5 PTHR45664:SF5 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-D3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anterior/posterior pattern specification#GO:0009952;embryo development#GO:0009790;skeletal system development#GO:0001501;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;skeletal system morphogenesis#GO:0048705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006343.1|UniProtKB=W5MH00 W5MH00 PTHR10356:SF5 ALLOGRAFT INFLAMMATORY FACTOR-1 ALLOGRAFT INFLAMMATORY FACTOR 1-LIKE protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;protein-containing complex binding#GO:0044877;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036 cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;supramolecular polymer#GO:0099081;plasma membrane region#GO:0098590;supramolecular complex#GO:0099080;actin filament#GO:0005884;ruffle membrane#GO:0032587;cytoskeleton#GO:0005856;ruffle#GO:0001726;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;leading edge membrane#GO:0031256;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cell projection membrane#GO:0031253 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000011045.1|UniProtKB=W5MYW3 W5MYW3 PTHR23150:SF37 SULFATASE MODIFYING FACTOR 1, 2 FORMYLGLYCINE-GENERATING ENZYME oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000007466.1|UniProtKB=W5ML01 W5ML01 PTHR24409:SF306 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 423 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000015422.1|UniProtKB=W5NEC0 W5NEC0 PTHR12752:SF3 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 5 lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000009014.1|UniProtKB=W5MRH6 W5MRH6 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 binding#GO:0005488;tetrapyrrole binding#GO:0046906;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006217.1|UniProtKB=W5MGJ7 W5MGJ7 PTHR31395:SF3 SHISA PROTEIN SHISA-LIKE-2A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007057.1|UniProtKB=W5MJI0 W5MJI0 PTHR14819:SF5 GTP-BINDING INTERFERON-INDUCED VERY LARGE GTPASE 1 LEPOC|Ensembl=ENSLOCG00000009740.1|UniProtKB=W5MU40 W5MU40 PTHR11485:SF34 TRANSFERRIN SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT BETA establishment of protein localization#GO:0045184;protein targeting to ER#GO:0045047;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;rough endoplasmic reticulum#GO:0005791;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000016127.1|UniProtKB=W5NGW5 W5NGW5 PTHR24169:SF4 NUCLEAR FACTOR NF-KAPPA-B PROTEIN PROTO-ONCOGENE C-REL transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of transcription by RNA polymerase II#GO:0045944;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;non-canonical NF-kappaB signal transduction#GO:0038061;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;intracellular signaling cassette#GO:0141124;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;defense response to other organism#GO:0098542;immune system process#GO:0002376;response to peptide#GO:1901652;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;canonical NF-kappaB signal transduction#GO:0007249;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;response to external biotic stimulus#GO:0043207;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252 Toll receptor signaling pathway#P00054>NFkappaB#P01354;Apoptosis signaling pathway#P00006>NFkappaB#P00297;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859 LEPOC|Ensembl=ENSLOCG00000007652.1|UniProtKB=W5MLM1 W5MLM1 PTHR13780:SF38 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1 cation binding#GO:0043169;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular response to glucose starvation#GO:0042149;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to nutrient levels#GO:0031667;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;regulation of carbohydrate metabolic process#GO:0006109;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of carbohydrate biosynthetic process#GO:0043255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891 intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 LEPOC|Ensembl=ENSLOCG00000002252.1|UniProtKB=W5M2M6 W5M2M6 PTHR13872:SF49 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687 membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000017143.1|UniProtKB=W5NKM7 W5NKM7 PTHR46806:SF1 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010978.1|UniProtKB=W5MYK6 W5MYK6 PTHR17537:SF6 TRANSDUCER OF ERBB2 TOB PROTEIN TOB1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006675.1|UniProtKB=W5MI56 W5MI56 PTHR15597:SF45 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;multicellular organism development#GO:0007275;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000007484.1|UniProtKB=W5ML39 W5ML39 PTHR11801:SF41 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to endogenous stimulus#GO:0009719;response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;cell surface receptor signaling pathway via STAT#GO:0097696;response to chemical#GO:0042221;response to cytokine#GO:0034097;defense response to other organism#GO:0098542;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;response to stress#GO:0006950;cell surface receptor signaling pathway#GO:0007166;response to external biotic stimulus#GO:0043207;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;response to peptide hormone#GO:0043434;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;immune response#GO:0006955;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of gene expression#GO:0010468;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway via JAK-STAT#GO:0007259 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 JAK/STAT signaling pathway#P00038>STAT#P01027;EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173;Interleukin signaling pathway#P00036>STAT#P00996 LEPOC|Ensembl=ENSLOCG00000006074.1|UniProtKB=W5MG27 W5MG27 PTHR14189:SF0 PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED PROTEIN PHOSPHATASE METHYLESTERASE 1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012071.1|UniProtKB=W5N2J3 W5N2J3 PTHR23239:SF32 INTERMEDIATE FILAMENT PHAKININ cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000002835.1|UniProtKB=W5M4N6 W5M4N6 PTHR19300:SF42 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001194.1|UniProtKB=W5LYY9 W5LYY9 PTHR14677:SF46 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED ZINC FINGER AN1-TYPE CONTAINING 2A-RELATED modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein targeting#GO:0006605;catabolic process#GO:0009056;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein targeting to ER#GO:0045047;cellular process#GO:0009987;establishment of protein localization#GO:0045184;proteasomal protein catabolic process#GO:0010498;establishment of protein localization to endoplasmic reticulum#GO:0072599 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014767.1|UniProtKB=W5NC24 W5NC24 PTHR10306:SF35 SYNAPTOPHYSIN SYNAPTOPHYSIN exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;presynaptic active zone#GO:0048786;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007041.1|UniProtKB=W5MJG3 W5MJG3 PTHR48081:SF36 AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C KYNURENINE FORMAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015047.1|UniProtKB=W5ND09 W5ND09 PTHR44090:SF1 WD REPEAT-CONTAINING PROTEIN 61 SUPERKILLER COMPLEX PROTEIN 8 intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000011111.1|UniProtKB=W5MZ44 W5MZ44 PTHR15160:SF10 VON HIPPEL-LINDAU PROTEIN VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR ubiquitin-like ligase-substrate adaptor activity#GO:1990756;transcription regulator activity#GO:0140110;enzyme-substrate adaptor activity#GO:0140767;transcription corepressor activity#GO:0003714;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674 regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012887.1|UniProtKB=W5N5F5 W5N5F5 PTHR38654:SF1 BUCKY BALL-RELATED BUCKY BALL LEPOC|Ensembl=ENSLOCG00000005811.1|UniProtKB=W5MF60 W5MF60 PTHR11873:SF2 RETINOL-BINDING PROTEIN 4 RETINOL-BINDING PROTEIN 4 binding#GO:0005488;small molecule binding#GO:0036094;alcohol binding#GO:0043178;lipid binding#GO:0008289 macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014890.1|UniProtKB=W5NCI4 W5NCI4 PTHR46017:SF1 ALPHA-MANNOSIDASE 2C1 ALPHA-MANNOSIDASE 2C1 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 primary metabolic process#GO:0044238;cellular process#GO:0009987;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311 LEPOC|Ensembl=ENSLOCG00000008564.1|UniProtKB=W5MPW0 W5MPW0 GATB PTHR11659:SF5 GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translation#GO:0006412;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007984.1|UniProtKB=W5MMU9 W5MMU9 PTHR13906:SF16 PORCUPINE MEMBRANE-BOUND ACYLGLYCEROPHOSPHATIDYLINOSITOL O-ACYLTRANSFERASE MBOAT7 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;lipid modification#GO:0030258 membrane#GO:0016020;organelle membrane contact site#GO:0044232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000007989.1|UniProtKB=W5MMU0 W5MMU0 PTHR31633:SF1 H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;ribonucleoprotein complex biogenesis#GO:0022613;cellular component assembly#GO:0022607;ribosome biogenesis#GO:0042254;protein-containing complex organization#GO:0043933;protein-RNA complex assembly#GO:0022618;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;ribonucleoprotein complex#GO:1990904 LEPOC|Ensembl=ENSLOCG00000015255.1|UniProtKB=W5NDR3 W5NDR3 PTHR22798:SF0 MCT-1 PROTEIN MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1 translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000007252.1|UniProtKB=W5MK67 W5MK67 PTHR24412:SF475 KELCH PROTEIN KELCH-LIKE PROTEIN 17 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015235.1|UniProtKB=W5NDN9 W5NDN9 PTHR10024:SF46 SYNAPTOTAGMIN SYNAPTOTAGMIN-10 SNARE binding#GO:0000149;phospholipid binding#GO:0005543;binding#GO:0005488;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;molecular sensor activity#GO:0140299;protein binding#GO:0005515 synaptic signaling#GO:0099536;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;regulation of localization#GO:0032879;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;localization#GO:0051179;regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016734.1|UniProtKB=W5NJ70 W5NJ70 PTHR10257:SF89 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT DELTA ISOFORM enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;enzyme activator activity#GO:0008047 cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000016415.1|UniProtKB=W5NI15 W5NI15 PTHR22950:SF207 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID SYMPORTER 2 neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;localization#GO:0051179;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 LEPOC|Ensembl=ENSLOCG00000014531.1|UniProtKB=W5NB76 W5NB76 PTHR11759:SF76 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005724.1|UniProtKB=W5MEU8 W5MEU8 PTHR24006:SF660 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 35 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006067.1|UniProtKB=W5MG16 W5MG16 PTHR12645:SF0 ALR/ERV SULFHYDRYL OXIDASE oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;heterocyclic compound binding#GO:1901363;disulfide oxidoreductase activity#GO:0015036;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;protein-disulfide reductase activity#GO:0015035;anion binding#GO:0043168;binding#GO:0005488;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001096.1|UniProtKB=W5LYQ6 W5LYQ6 PTHR24255:SF28 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED ST14 TRANSMEMBRANE SERINE PROTEASE MATRIPTASE B serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000001332.1|UniProtKB=W5LZK6 W5LZK6 PTHR11139:SF130 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE-PROTEIN KINASE ATM catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;DNA metabolic process#GO:0006259;cellular response to abiotic stimulus#GO:0071214;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;apoptotic process#GO:0006915;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;positive regulation of DNA metabolic process#GO:0051054;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of telomere maintenance via telomere lengthening#GO:1904356;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;regulation of TOR signaling#GO:0032006;metabolic process#GO:0008152;negative regulation of TORC1 signaling#GO:1904262;double-strand break repair#GO:0006302;regulation of DNA metabolic process#GO:0051052;response to ionizing radiation#GO:0010212;signaling#GO:0023052;cellular response to radiation#GO:0071478;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component organization#GO:0051130;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;positive regulation of organelle organization#GO:0010638;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;response to radiation#GO:0009314;regulation of signal transduction#GO:0009966;nucleobase-containing compound metabolic process#GO:0006139;regulation of chromosome organization#GO:0033044;DNA repair#GO:0006281;apoptotic signaling pathway#GO:0097190;regulation of telomere maintenance#GO:0032204;regulation of TORC1 signaling#GO:1903432;nucleic acid metabolic process#GO:0090304;cell death#GO:0008219;cellular response to environmental stimulus#GO:0104004;negative regulation of TOR signaling#GO:0032007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>ATM#P04669;p53 pathway#P00059>ATM/ATR#P01481 LEPOC|Ensembl=ENSLOCG00000004305.1|UniProtKB=W5M9T7 W5M9T7 PTHR23354:SF120 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED OXIDATION RESISTANCE PROTEIN 1 ISOFORM X1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;response to oxidative stress#GO:0006979;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000014873.1|UniProtKB=W5NCF9 W5NCF9 PTHR11866:SF7 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTACYCLIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;negative regulation of cellular process#GO:0048523;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;negative regulation of cell population proliferation#GO:0008285;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 LEPOC|Ensembl=ENSLOCG00000011043.1|UniProtKB=W5MYV2 W5MYV2 PTHR45632:SF15 LD33804P BTB DOMAIN-CONTAINING PROTEIN ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012324.1|UniProtKB=W5N3F5 W5N3F5 PTHR24367:SF21 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 2 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;system development#GO:0048731;anatomical structure development#GO:0048856;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cellular component organization#GO:0016043;cell junction assembly#GO:0034329 LEPOC|Ensembl=ENSLOCG00000012082.1|UniProtKB=W5N2K7 W5N2K7 PTHR19359:SF14 CYTOCHROME B5 CYTOCHROME B5 binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 intracellular organelle#GO:0043229;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015167.1|UniProtKB=W5NDF8 W5NDF8 PTHR11532:SF48 PROTEASE M14 CARBOXYPEPTIDASE ADIPOCYTE ENHANCER-BINDING PROTEIN 1 transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription repressor activity#GO:0001217;exopeptidase activity#GO:0008238;transcription regulatory region nucleic acid binding#GO:0001067;metalloexopeptidase activity#GO:0008235;peptidase activity#GO:0008233;sequence-specific DNA binding#GO:0043565;metallopeptidase activity#GO:0008237;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;carboxypeptidase activity#GO:0004180;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;sequence-specific double-stranded DNA binding#GO:1990837 metabolic process#GO:0008152;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;peptide metabolic process#GO:0006518;regulation of RNA metabolic process#GO:0051252;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015006.1|UniProtKB=W5NCW9 W5NCW9 PTHR12103:SF11 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 3 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000006163.1|UniProtKB=W5MGG0 W5MGG0 PTHR21502:SF8 ZINC FINGER PROTEIN DZIP1 CILIUM ASSEMBLY PROTEIN DZIP1L cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000009051.1|UniProtKB=W5MRM4 W5MRM4 PTHR10910:SF58 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN DOUBLE-STRANDED RNA-SPECIFIC EDITASE 1 hydrolase activity#GO:0016787;RNA binding#GO:0003723;adenosine deaminase activity#GO:0004000;catalytic activity, acting on a tRNA#GO:0140101;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;tRNA-specific adenosine deaminase activity#GO:0008251;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;adenosine to inosine editing#GO:0006382;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;base conversion or substitution editing#GO:0016553 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017572.1|UniProtKB=W5NM18 W5NM18 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009921.1|UniProtKB=W5MUS3 W5MUS3 PTHR19856:SF8 WD-REPEATCONTAINING PROTEIN WDR1 WD REPEAT-CONTAINING PROTEIN 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 actin filament depolymerization#GO:0030042;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;protein-containing complex organization#GO:0043933;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular component disassembly#GO:0022411;actin polymerization or depolymerization#GO:0008154;protein depolymerization#GO:0051261;developmental process#GO:0032502;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;protein-containing complex disassembly#GO:0032984;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006000.1|UniProtKB=W5MFU0 W5MFU0 PTHR24409:SF451 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 431-LIKE DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002940.1|UniProtKB=W5M503 W5M503 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000003907.1|UniProtKB=W5M8F2 W5M8F2 PTHR16705:SF12 COMPLEXIN COMPLEXIN-3 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;export from cell#GO:0140352;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of signaling#GO:0023051;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulated exocytosis#GO:0045055 membrane#GO:0016020;presynapse#GO:0098793;neuron projection#GO:0043005;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cell junction#GO:0030054;axon terminus#GO:0043679;membrane protein complex#GO:0098796;SNARE complex#GO:0031201;synapse#GO:0045202;cellular anatomical structure#GO:0110165;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuron projection terminus#GO:0044306;axon#GO:0030424;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007469.1|UniProtKB=W5ML07 W5ML07 PTHR31214:SF3 PROTEIN FAM221A-RELATED PROTEIN FAM221B LEPOC|Ensembl=ENSLOCG00000005665.1|UniProtKB=W5MEM8 W5MEM8 PTHR28640:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 6 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000016503.1|UniProtKB=W5NIC9 W5NIC9 PTHR11685:SF448 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE PARKIN protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;cellular process#GO:0009987;autophagy#GO:0006914;regulation of trans-synaptic signaling#GO:0099177;macroautophagy#GO:0016236;biological regulation#GO:0065007;macromolecule catabolic process#GO:0009057;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mitophagy#GO:0000423;ubiquitin-dependent protein catabolic process#GO:0006511 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Parkin#P01216 LEPOC|Ensembl=ENSLOCG00000010368.1|UniProtKB=W5MWE7 W5MWE7 PTHR24214:SF6 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 4 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;organelle organization#GO:0006996;cellular process#GO:0009987;heart development#GO:0007507;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component organization#GO:0016043;circulatory system development#GO:0072359;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin filament bundle#GO:0032432;myofibril#GO:0030016;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;actomyosin#GO:0042641;cell-cell junction#GO:0005911;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;I band#GO:0031674;actin filament#GO:0005884;cytoskeleton#GO:0005856;stress fiber#GO:0001725;adherens junction#GO:0005912;cell junction#GO:0030054;sarcomere#GO:0030017;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000014157.1|UniProtKB=W5N9Y1 W5N9Y1 PTHR15583:SF11 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR B molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;positive regulation of metabolic process#GO:0009893;cell communication#GO:0007154;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;response to peptide#GO:1901652;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008662.1|UniProtKB=W5MQ81 W5MQ81 PTHR46035:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 4 HSP70_HSP90 CO-CHAPERONE CNS1 HOMOLOG Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000012360.1|UniProtKB=W5N3K7 W5N3K7 PTHR10353:SF291 GLYCOSYL HYDROLASE CYTOSOLIC BETA-GLUCOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 ceramide metabolic process#GO:0006672;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 glycosidase#PC00110;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004538.1|UniProtKB=W5MAL9 W5MAL9 PTHR19957:SF38 SYNTAXIN T-SNARE DOMAIN-CONTAINING PROTEIN 1 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284 intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;endomembrane system#GO:0012505;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 SNARE protein#PC00034 Parkinson disease#P00049>Syntaxin#P01215;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772 LEPOC|Ensembl=ENSLOCG00000000698.1|UniProtKB=W5LXB5 W5LXB5 PTHR23266:SF420 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006501.1|UniProtKB=W5MHJ5 W5MHJ5 PTHR22957:SF337 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 5 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 intracellular transport#GO:0046907;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;retromer complex#GO:0030904;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000013079.1|UniProtKB=W5N650 W5N650 PTHR13542:SF0 LSM12 HOMOLOG PROTEIN LSM12 LEPOC|Ensembl=ENSLOCG00000004365.1|UniProtKB=W5MA04 W5MA04 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005843.1|UniProtKB=W5MF97 W5MF97 PTHR24412:SF35 KELCH PROTEIN ACTIN-BINDING PROTEIN IPP ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008410.1|UniProtKB=W5MPD4 W5MPD4 PTHR10663:SF320 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-3 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000000330.1|UniProtKB=W5LW50 W5LW50 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006273.1|UniProtKB=W5MGS5 W5MGS5 PTHR12670:SF21 CERAMIDASE NEUTRAL CERAMIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 ceramide metabolic process#GO:0006672;sphingoid biosynthetic process#GO:0046520;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid catabolic process#GO:0016042;alcohol biosynthetic process#GO:0046165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000007621.1|UniProtKB=W5MLI7 W5MLI7 PTHR43330:SF28 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1D, MITOCHONDRIAL exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000003968.1|UniProtKB=W5M8N6 W5M8N6 PTHR24055:SF609 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 8-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>JNK1-3#P00628;TGF-beta signaling pathway#P00052>JNK#P01284;Ras Pathway#P04393>JNK#P04572;FAS signaling pathway#P00020>JNK#P00615;Integrin signalling pathway#P00034>Jnk#P00951;Apoptosis signaling pathway#P00006>JNK#P00274;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Parkinson disease#P00049>SAPK#P01219;Toll receptor signaling pathway#P00054>JNK#P01375;Angiogenesis#P00005>JNK1#P00221;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Oxidative stress response#P00046>JNK1/2#P01129 LEPOC|Ensembl=ENSLOCG00000014257.1|UniProtKB=W5NA94 W5NA94 PTHR22972:SF9 SERINE/THREONINE PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE PEAK1 protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001231.1|UniProtKB=W5LZ36 W5LZ36 PTHR24394:SF22 ZINC FINGER PROTEIN HYPERMETHYLATED IN CANCER 2 PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008549.1|UniProtKB=W5MPV9 W5MPV9 PTHR11453:SF32 ANION EXCHANGE PROTEIN SODIUM-DRIVEN CHLORIDE BICARBONATE EXCHANGER solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of biological quality#GO:0065008 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000005365.1|UniProtKB=W5MDL6 W5MDL6 PTHR14130:SF3 3BP-1 RELATED RHOGAP RHO GTPASE-ACTIVATING PROTEIN 17 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of signal transduction#GO:0009968;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of response to stimulus#GO:0048583;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009277.1|UniProtKB=W5MSF6 W5MSF6 PTHR14499:SF5 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING POTASSIUM CHANNEL REGULATORY PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010710.1|UniProtKB=W5MXL6 W5MXL6 PTHR13413:SF0 YLP MOTIF CONTAINING PROTEIN NUCLEAR PROTEIN ZAP YLP MOTIF-CONTAINING PROTEIN 1 regulation of chromosome organization#GO:0033044;regulation of telomere maintenance#GO:0032204;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of DNA metabolic process#GO:0051052;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003415.1|UniProtKB=W5M6Q0 W5M6Q0 PTHR11550:SF47 CTP SYNTHASE CTP SYNTHASE 1-RELATED identical protein binding#GO:0042802;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;ligase activity#GO:0016874;catalytic activity#GO:0003824;binding#GO:0005488 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;ribonucleoside triphosphate biosynthetic process#GO:0009201;pyrimidine nucleobase metabolic process#GO:0006206;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;ribose phosphate biosynthetic process#GO:0046390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;supramolecular fiber#GO:0099512 metabolite interconversion enzyme#PC00262;ligase#PC00142 De novo pyrimidine ribonucleotides biosythesis#P02740>CTP synthase#P02931 LEPOC|Ensembl=ENSLOCG00000016651.1|UniProtKB=W5NIV9 W5NIV9 PTHR46763:SF2 DYNEIN REGULATORY COMPLEX PROTEIN 8 DYNEIN REGULATORY COMPLEX PROTEIN 8 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000005439.1|UniProtKB=W5MDV3 W5MDV3 PTHR16056:SF39 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN TESTIS-EXPRESSED PROTEIN 10 protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000005109.1|UniProtKB=W5MCP1 W5MCP1 PTHR23192:SF29 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 2A regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001235.1|UniProtKB=W5LZ41 W5LZ41 PTHR10201:SF115 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-27 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000011454.1|UniProtKB=W5N0E0 W5N0E0 PTHR15239:SF6 NUCLEAR EXPORT MEDIATOR FACTOR NEMF RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF ribosomal large subunit binding#GO:0043023;nucleic acid binding#GO:0003676;binding#GO:0005488;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;tRNA binding#GO:0000049;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723 protein catabolic process#GO:0030163;translation#GO:0006412;modification-dependent macromolecule catabolic process#GO:0043632;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;rescue of stalled cytosolic ribosome#GO:0072344;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cytoplasmic translation#GO:0002181;catabolic process#GO:0009056;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;translational elongation#GO:0006414;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;gene expression#GO:0010467 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000015566.1|UniProtKB=W5NEV6 W5NEV6 PTHR46698:SF2 CROSSVEINLESS 2 KIELIN_CHORDIN-LIKE PROTEIN regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of BMP signaling pathway#GO:0030510;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of response to stimulus#GO:0048583;positive regulation of BMP signaling pathway#GO:0030513 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000013600.1|UniProtKB=W5N810 W5N810 PTHR10985:SF135 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY AND ENHANCER OF SPLIT RELATED-7 ISOFORM X1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of neurogenesis#GO:0050767;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000016970.1|UniProtKB=W5NK19 W5NK19 PTHR24023:SF880 COLLAGEN ALPHA COLLAGEN ALPHA-1(X) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000010220.1|UniProtKB=W5MVV3 W5MVV3 PTHR47510:SF11 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013325.1|UniProtKB=W5N722 W5N722 PTHR12894:SF49 CNH DOMAIN CONTAINING VAM6_VPS39-LIKE PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515;small GTPase binding#GO:0031267 cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;macroautophagy#GO:0016236;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;transport#GO:0006810;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;vacuole fusion#GO:0097576;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;localization#GO:0051179 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle tethering complex#GO:0099023;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000016549.1|UniProtKB=W5NII0 W5NII0 PTHR13850:SF6 PLEIOTROPHIN FAMILY MEMBER PLEIOTROPHIN signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000002733.1|UniProtKB=W5M4B6 W5M4B6 PTHR43134:SF1 SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 protein targeting to ER#GO:0045047;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of protein localization#GO:0045184 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 protein-binding activity modulator#PC00095;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000010511.1|UniProtKB=W5MWY2 W5MWY2 PTHR24058:SF43 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713 apoptotic signaling pathway#GO:0097190;cell surface receptor signaling pathway#GO:0007166;DNA damage response#GO:0006974;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;intracellular signal transduction#GO:0035556;smoothened signaling pathway#GO:0007224;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000887.1|UniProtKB=W5LXY9 W5LXY9 PTHR23065:SF6 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 F-BAR DOMAIN ONLY PROTEIN 1 transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607 clathrin-coated vesicle#GO:0030136;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000005034.1|UniProtKB=W5MCF3 W5MCF3 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000017036.1|UniProtKB=W5NK97 W5NK97 PTHR12472:SF1 RAB3-GAP REGULATORY DOMAIN RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 signaling#GO:0023052;catabolic process#GO:0009056;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;localization#GO:0051179;cell communication#GO:0007154;localization within membrane#GO:0051668;macroautophagy#GO:0016236;establishment of protein localization to endoplasmic reticulum#GO:0072599;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular process#GO:0009987;establishment of protein localization#GO:0045184;autophagy#GO:0006914;synaptic signaling#GO:0099536;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;metabolic process#GO:0008152 synaptic membrane#GO:0097060;cell junction#GO:0030054;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;vacuole#GO:0005773;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;intracellular organelle#GO:0043229;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000001275.1|UniProtKB=W5LZA1 W5LZA1 PTHR10977:SF3 DIPHOSPHOMEVALONATE DECARBOXYLASE DIPHOSPHOMEVALONATE DECARBOXYLASE lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;phospholipid biosynthetic process#GO:0008654;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phospholipid metabolic process#GO:0006644;acetyl-CoA metabolic process#GO:0006084;isoprenoid biosynthetic process#GO:0008299;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lyase#PC00144;decarboxylase#PC00089 Cholesterol biosynthesis#P00014>Diphosphomevalonate decarboxylase#P00496 LEPOC|Ensembl=ENSLOCG00000013288.1|UniProtKB=W5N6W1 W5N6W1 PTHR24390:SF261 ZINC FINGER PROTEIN SI:CH211-284E13.5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000009793.1|UniProtKB=W5MUB3 W5MUB3 PTHR23257:SF945 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 13 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004216.1|UniProtKB=W5M9L8 W5M9L8 PTHR11034:SF20 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG3 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000014560.1|UniProtKB=W5NBB5 W5NBB5 PTHR11851:SF116 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585 endopeptidase complex#GO:1905369;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;peptidase complex#GO:1905368;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010772.1|UniProtKB=W5MXT6 W5MXT6 PTHR10454:SF234 CASPASE CASPASE 10, APOPTOSIS-RELATED CYSTEINE PEPTIDASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;programmed cell death#GO:0012501;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004178.1|UniProtKB=W5M9G4 W5M9G4 PTHR43108:SF1 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan metabolic process#GO:0006029;negative regulation of biological process#GO:0048519;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;carbohydrate derivative metabolic process#GO:1901135;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of cytokine production#GO:0001819;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;carbohydrate derivative catabolic process#GO:1901136;regulation of cell communication#GO:0010646;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009118.1|UniProtKB=W5MRW4 W5MRW4 PTHR12750:SF10 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 2 phosphotransferase activity, phosphate group as acceptor#GO:0016776;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137;nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000002697.1|UniProtKB=W5M476 W5M476 PTHR13847:SF200 SARCOSINE DEHYDROGENASE-RELATED SARCOSINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000004883.1|UniProtKB=W5MBX0 W5MBX0 PTHR19212:SF6 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 2 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007795.1|UniProtKB=W5MM69 W5MM69 PTHR24270:SF21 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR cargo receptor activity#GO:0038024;low-density lipoprotein particle receptor activity#GO:0005041 lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;cholesterol homeostasis#GO:0042632;sterol transport#GO:0015918;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular transport#GO:0046907;homeostatic process#GO:0042592;intracellular sterol transport#GO:0032366;endocytosis#GO:0006897;lipid homeostasis#GO:0055088;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;cellular localization#GO:0051641;lipid localization#GO:0010876 plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 transfer/carrier protein#PC00219;apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000014790.1|UniProtKB=W5NC53 W5NC53 PTHR11890:SF10 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER X-LINKED INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN-LIKE 2 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015216.1|UniProtKB=W5NDL7 W5NDL7 PTHR13381:SF0 RNA POLYMERASE II HOLOENZYME COMPONENT SRB7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000014474.1|UniProtKB=W5NB08 W5NB08 PTHR11753:SF10 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-3 COMPLEX SUBUNIT SIGMA-2 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013186.1|UniProtKB=W5N6I4 W5N6I4 PTHR14499:SF10 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING POTASSIUM CHANNEL TETRAMERIZATION DOMAIN CONTAINING 6 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009587.1|UniProtKB=W5MTK2 W5MTK2 PTHR23309:SF9 3-HYDROXYACYL-COA DEHYROGENASE PEROXISOMAL BIFUNCTIONAL ENZYME oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000008826.1|UniProtKB=W5MQS7 W5MQS7 PTHR11848:SF150 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 8 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 striated muscle tissue development#GO:0014706;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;muscle organ development#GO:0007517;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;animal organ development#GO:0048513;signal transduction#GO:0007165;cellular process#GO:0009987;skeletal muscle tissue development#GO:0007519;transforming growth factor beta receptor signaling pathway#GO:0007179;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;tissue development#GO:0009888;response to transforming growth factor beta#GO:0071559;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;muscle tissue development#GO:0060537;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000002458.1|UniProtKB=W5M3C9 W5M3C9 PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 CILIARY MICROTUBULE INNER PROTEIN 2B LEPOC|Ensembl=ENSLOCG00000011989.1|UniProtKB=W5N289 W5N289 PTHR43272:SF80 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000004368.1|UniProtKB=W5MA13 W5MA13 PTHR19876:SF2 COATOMER COATOMER SUBUNIT BETA' cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;COPI-coated vesicle#GO:0030137;cytoplasm#GO:0005737;vesicle coat#GO:0030120 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000008886.1|UniProtKB=W5MR03 W5MR03 PTHR15819:SF9 TRANSMEMBRANE PROTEIN FAM155 NALCN CHANNEL AUXILIARY FACTOR 1 transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000001627.1|UniProtKB=W5M0I8 W5M0I8 PTHR10972:SF213 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 5 small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934;alcohol binding#GO:0043178;steroid binding#GO:0005496;lipid binding#GO:0008289;cholesterol binding#GO:0015485 phospholipid transport#GO:0015914;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;macromolecule localization#GO:0033036;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014605.1|UniProtKB=W5NBG4 W5NBG4 PTHR45960:SF3 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 3 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Gab#P00563 LEPOC|Ensembl=ENSLOCG00000000788.1|UniProtKB=W5LXL8 W5LXL8 PTHR15505:SF3 RIIA DOMAIN-CONTAINING PROTEIN 1 CILIOGENESIS-ASSOCIATED TTC17-INTERACTING PROTEIN actin filament-based process#GO:0030029;cilium organization#GO:0044782;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010 LEPOC|Ensembl=ENSLOCG00000001047.1|UniProtKB=W5LYH2 W5LYH2 PTHR10655:SF13 LYSOPHOSPHOLIPASE-RELATED ACYL-PROTEIN THIOESTERASE 2 phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;catalytic activity, acting on a protein#GO:0140096;carboxylic ester hydrolase activity#GO:0052689;thiolester hydrolase activity#GO:0016790;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787 negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of protein localization to membrane#GO:1905475;lipid catabolic process#GO:0016042;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;catabolic process#GO:0009056;negative regulation of transport#GO:0051051;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lipase#PC00143;phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000002110.1|UniProtKB=W5M269 W5M269 PTHR11339:SF228 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED OTOGELIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000004396.1|UniProtKB=W5MA49 W5MA49 PTHR10404:SF50 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE AMINOPEPTIDASE NAALADL1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;peptidase activity#GO:0008233 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000005691.1|UniProtKB=W5MER2 W5MER2 PTHR10219:SF20 GLYCOLIPID TRANSFER PROTEIN-RELATED CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN transporter activity#GO:0005215;phospholipid binding#GO:0005543;ion binding#GO:0043167;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014 nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;ceramide transport#GO:0035627;membrane organization#GO:0061024;lipid localization#GO:0010876;transport#GO:0006810;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000005471.1|UniProtKB=W5ME15 W5ME15 PTHR12442:SF5 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 3 protein binding#GO:0005515;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;inner dynein arm assembly#GO:0036159;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;inner dynein arm#GO:0036156 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001636.1|UniProtKB=W5M0H5 W5M0H5 PTHR13048:SF0 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;cis-Golgi network#GO:0005801;vesicle tethering complex#GO:0099023;membrane#GO:0016020;cytosol#GO:0005829;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000006896.1|UniProtKB=W5MIX8 W5MIX8 PTHR11589:SF8 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIN-4 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;neuron development#GO:0048666;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;regulation of trans-synaptic signaling#GO:0099177;nervous system development#GO:0007399;negative regulation of neuron apoptotic process#GO:0043524;neuron projection development#GO:0031175;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular response to nerve growth factor stimulus#GO:1990090;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182 cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle#GO:0030133;presynapse#GO:0098793;secretory vesicle#GO:0099503;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 growth factor#PC00112;neurotrophic factor#PC00163 LEPOC|Ensembl=ENSLOCG00000006290.1|UniProtKB=W5MGU2 W5MGU2 PTHR18929:SF262 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 protein maturation#GO:0051604;gene expression#GO:0010467;response to stimulus#GO:0050896;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011476.1|UniProtKB=W5N0F2 W5N0F2 PTHR15288:SF2 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2D guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000015460.1|UniProtKB=W5NEG9 W5NEG9 PTHR46330:SF6 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B HEMATOPOIETIC DEATH RECEPTOR ISOFORM X1-RELATED extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;apoptotic signaling pathway#GO:0097190;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013712.1|UniProtKB=W5N8F9 W5N8F9 PTHR23335:SF9 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 2 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000015599.1|UniProtKB=W5NEZ6 W5NEZ6 PTHR21603:SF16 ANTIGEN KI-67-LIKE PROTEIN CELL DIVISION CYCLE-ASSOCIATED PROTEIN 2 molecular condensate scaffold activity#GO:0140693;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 sexual reproduction#GO:0019953;regulation of cell cycle#GO:0051726;reproductive process#GO:0022414;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of mitotic nuclear division#GO:0007088;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of nuclear division#GO:0051783;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000005856.1|UniProtKB=W5MFB5 W5MFB5 PTHR15708:SF8 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED PROTEIN MTSS 2 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000013284.1|UniProtKB=W5N6V6 W5N6V6 PTHR11652:SF14 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000003589.1|UniProtKB=W5M7C3 W5M7C3 PTHR31350:SF21 SI:DKEY-261L7.2 F-BOX ONLY PROTEIN 21 LEPOC|Ensembl=ENSLOCG00000007570.1|UniProtKB=W5MLC8 W5MLC8 PTHR12718:SF2 CELL CYCLE CONTROL PROTEIN CWF15 SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009351.1|UniProtKB=W5MSQ5 W5MSQ5 PTHR11632:SF51 SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;anaerobic respiration#GO:0009061 membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cell periphery#GO:0071944;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;respiratory chain complex II (succinate dehydrogenase)#GO:0045273 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000004194.1|UniProtKB=W5M9F1 W5M9F1 PTHR20859:SF55 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON LAMBDA RECEPTOR 1 immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017249.1|UniProtKB=W5NL26 W5NL26 PTHR23227:SF87 BUCENTAUR RELATED PROTEIN CFDP2 LEPOC|Ensembl=ENSLOCG00000004319.1|UniProtKB=W5M9U8 W5M9U8 PTHR28546:SF1 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURON-SPECIFIC VESICULAR PROTEIN CALCYON regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;macromolecule metabolic process#GO:0043170;regulation of biological quality#GO:0065008;protein transport#GO:0015031;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;biological regulation#GO:0065007 cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000011761.1|UniProtKB=W5N1F3 W5N1F3 PTHR10903:SF170 GTPASE, IMAP FAMILY MEMBER-RELATED AIG1-TYPE G DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000003746.1|UniProtKB=W5M7X3 W5M7X3 PTHR13586:SF1 SCD6 PROTEIN-RELATED PROTEIN LSM14 HOMOLOG B binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607;P-body assembly#GO:0033962;cellular process#GO:0009987;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001324.1|UniProtKB=W5LZE9 W5LZE9 PTHR36465:SF2 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 3 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 3 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016530.1|UniProtKB=W5NIG3 W5NIG3 LHCGR PTHR24372:SF1 GLYCOPROTEIN HORMONE RECEPTOR LUTROPIN-CHORIOGONADOTROPIC HORMONE RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;female gonad development#GO:0008585;system development#GO:0048731;reproductive system development#GO:0061458;multicellular organismal reproductive process#GO:0048609;cell communication#GO:0007154;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;developmental process#GO:0032502;male sex differentiation#GO:0046661;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;development of primary male sexual characteristics#GO:0046546;biological regulation#GO:0065007;gonad development#GO:0008406;multicellular organismal process#GO:0032501;rhythmic process#GO:0048511;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;reproductive structure development#GO:0048608;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;development of primary sexual characteristics#GO:0045137;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;multicellular organism development#GO:0007275;animal organ development#GO:0048513;signal transduction#GO:0007165;male gonad development#GO:0008584;cellular process#GO:0009987;sex differentiation#GO:0007548;response to hormone#GO:0009725;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010739.1|UniProtKB=W5MXR5 W5MXR5 PTHR21646:SF45 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;regulation of protein stability#GO:0031647;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000009109.1|UniProtKB=W5MRY2 W5MRY2 PTHR24092:SF33 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IH ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 lipid transport#GO:0006869;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;recycling endosome#GO:0055037;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001844.1|UniProtKB=W5M171 W5M171 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune system process#GO:0002376;cell communication#GO:0007154;signal transduction#GO:0007165;immune response#GO:0006955;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004769.1|UniProtKB=W5MBG9 W5MBG9 PTHR11596:SF92 ALKALINE PHOSPHATASE INTESTINAL-TYPE ALKALINE PHOSPHATASE ISOFORM X1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000005003.1|UniProtKB=W5MCD6 W5MCD6 PTHR45728:SF5 ACETYL-COA CARBOXYLASE, ISOFORM A ACETYL-COA CARBOXYLASE 1 catalytic activity#GO:0003824;ligase activity#GO:0016874 biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006513.1|UniProtKB=W5MHL4 W5MHL4 PTHR12308:SF16 ANOCTAMIN ANOCTAMIN-3 intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000006019.1|UniProtKB=W5MFV8 W5MFV8 PTHR10516:SF452 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYLPROLYL ISOMERASE cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of monoatomic ion transport#GO:0043269;regulation of calcium ion transport#GO:0051924;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;calcium-mediated signaling#GO:0019722;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of system process#GO:0044057;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;regulation of heart contraction#GO:0008016;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;protein metabolic process#GO:0019538;intracellular signal transduction#GO:0035556;protein maturation#GO:0051604;gene expression#GO:0010467;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of release of sequestered calcium ion into cytosol#GO:0051279;metabolic process#GO:0008152;response to stimulus#GO:0050896;signaling#GO:0023052;protein folding#GO:0006457;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;regulation of muscle contraction#GO:0006937 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 LEPOC|Ensembl=ENSLOCG00000002302.1|UniProtKB=W5M2T0 W5M2T0 PTHR11995:SF14 NADH DEHYDROGENASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;NADH dehydrogenase activity#GO:0003954;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;electron transfer activity#GO:0009055 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic ion transport#GO:0006811;aerobic respiration#GO:0009060;metabolic process#GO:0008152;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000005661.1|UniProtKB=W5MEM3 W5MEM3 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED LEPOC|Ensembl=ENSLOCG00000007584.1|UniProtKB=W5MLE2 W5MLE2 PTHR11239:SF12 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on RNA#GO:0140098 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription termination#GO:0006353 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000015437.1|UniProtKB=W5NEE3 W5NEE3 PTHR11309:SF87 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 1 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;non-canonical Wnt signaling pathway#GO:0035567;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434;Angiogenesis#P00005>FRP#P00237 LEPOC|Ensembl=ENSLOCG00000013175.1|UniProtKB=W5N6H4 W5N6H4 PTHR37457:SF6 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED TRNA SELENOCYSTEINE-ASSOCIATED PROTEIN 1 tRNA binding#GO:0000049;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;translational elongation#GO:0006414;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;translation#GO:0006412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein biosynthetic process#GO:0160307 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000014255.1|UniProtKB=W5NA91 W5NA91 PTHR46040:SF1 HIGH MOBILITY GROUP PROTEIN 2 HIGH MOBILITY GROUP PROTEIN 20A regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000005814.1|UniProtKB=W5MF68 W5MF68 PTHR46522:SF1 CYTIDINE MONOPHOSPHATE-N-ACETYLNEURAMINIC ACID HYDROXYLASE INACTIVE CYTIDINE MONOPHOSPHATE-N-ACETYLNEURAMINIC ACID HYDROXYLASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;nucleotide-sugar metabolic process#GO:0009225;small molecule metabolic process#GO:0044281;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydroxylase#PC00122;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016490.1|UniProtKB=W5NIB0 W5NIB0 PTHR21051:SF4 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000007592.1|UniProtKB=W5MLG5 W5MLG5 PTHR16308:SF18 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER UBIQUITIN-ASSOCIATED PROTEIN 2-LIKE organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular process#GO:0009987;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;cytoplasmic stress granule assembly#GO:0034063;homeostatic process#GO:0042592;organelle assembly#GO:0070925;homeostasis of number of cells#GO:0048872;cellular component organization or biogenesis#GO:0071840;multicellular organismal-level homeostasis#GO:0048871 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;PcG protein complex#GO:0031519 LEPOC|Ensembl=ENSLOCG00000010988.1|UniProtKB=W5MYL3 W5MYL3 PTHR45476:SF1 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6 chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 transport#GO:0006810;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ion channel#PC00133 Nicotine pharmacodynamics pathway#P06587>CLIC6#P06611;Dopamine receptor mediated signaling pathway#P05912>CLIC6#P05968 LEPOC|Ensembl=ENSLOCG00000016422.1|UniProtKB=W5NI31 W5NI31 PTHR22903:SF3 PLEKHH PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 2 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of protein depolymerization#GO:1901880;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;cellular component organization or biogenesis#GO:0071840;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of organelle organization#GO:0010639;cellular component organization#GO:0016043;negative regulation of cellular component organization#GO:0051129;regulation of actin filament depolymerization#GO:0030834;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009016.1|UniProtKB=W5MRI3 W5MRI3 PTHR24006:SF710 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 38 cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000016833.1|UniProtKB=W5NJJ5 W5NJJ5 PTHR18860:SF3 14-3-3 PROTEIN 14-3-3 PROTEIN THETA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 LEPOC|Ensembl=ENSLOCG00000013701.1|UniProtKB=W5N8E0 W5N8E0 PTHR24115:SF322 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1C cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544 organelle localization#GO:0051640;axonal transport#GO:0098930;retrograde axonal transport#GO:0008090;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;axo-dendritic transport#GO:0008088;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle-mediated transport#GO:0016192;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650 microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004278.1|UniProtKB=W5M9Q3 W5M9Q3 PTHR24332:SF16 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;anterior/posterior axis specification#GO:0009948;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;embryonic pattern specification#GO:0009880;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;tube development#GO:0035295;animal gross anatomical part developmental process#GO:0160108;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007182.1|UniProtKB=W5MJY4 W5MJY4 PTHR10082:SF36 INTEGRIN BETA SUBUNIT INTEGRIN BETA-7 signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178 cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627;leukocyte migration#GO:0050900;biological regulation#GO:0065007;cell migration#GO:0016477;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;immune system process#GO:0002376;signaling#GO:0023052;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229 cell junction#GO:0030054;integrin complex#GO:0008305;anchoring junction#GO:0070161;signaling receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 LEPOC|Ensembl=ENSLOCG00000008771.1|UniProtKB=W5MQM5 W5MQM5 PTHR21367:SF1 ARGININE-TRNA-PROTEIN TRANSFERASE 1 ARGINYL-TRNA--PROTEIN TRANSFERASE 1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a tRNA#GO:0140101;acyltransferase activity#GO:0016746 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000001546.1|UniProtKB=W5M061 W5M061 PTHR31171:SF0 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 6 LY6_PLAUR DOMAIN-CONTAINING PROTEIN 6 acetylcholine receptor regulator activity#GO:0030548;signaling receptor regulator activity#GO:0030545;neurotransmitter receptor regulator activity#GO:0099602;molecular function regulator activity#GO:0098772 LEPOC|Ensembl=ENSLOCG00000006955.1|UniProtKB=W5MJ56 W5MJ56 PTHR23065:SF65 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 SH3-CONTAINING GRB2-LIKE PROTEIN 3-INTERACTING PROTEIN 1 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;protein-containing complex organization#GO:0043933;transport#GO:0006810;cellular component assembly#GO:0022607;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;clathrin-coated vesicle#GO:0030136 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006805.1|UniProtKB=W5MIN2 W5MIN2 PTHR23220:SF4 INTEGRIN ALPHA INTEGRIN ALPHA-V signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;integrin-mediated signaling pathway#GO:0007229;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;integrin complex#GO:0008305 cell adhesion molecule#PC00069;integrin#PC00126 CCKR signaling map#P06959>ITGAV#G07293;CCKR signaling map#P06959>ITGAV#G06999;CCKR signaling map#P06959>ITGAV#P07133;Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000017732.1|UniProtKB=W5NMH7 W5NMH7 PTHR24365:SF17 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 2 signaling receptor activity#GO:0038023;lipid binding#GO:0008289;molecular transducer activity#GO:0060089;binding#GO:0005488 cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell communication#GO:0007154;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR1,2,6#P01380;Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000006758.1|UniProtKB=W5MIG2 W5MIG2 PTHR23503:SF54 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carbohydrate transport#GO:0008643;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014741.1|UniProtKB=W5NBZ4 W5NBZ4 PTHR43884:SF47 ACYL-COA DEHYDROGENASE ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000007340.1|UniProtKB=W5MKJ9 W5MKJ9 PTHR22967:SF10 SERINE/THREONINE PROTEIN KINASE BMP-2-INDUCIBLE PROTEIN KINASE protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;enzyme regulator activity#GO:0030234;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of response to stimulus#GO:0048583;regulation of endocytosis#GO:0030100;positive regulation of response to stimulus#GO:0048584;regulation of bone mineralization#GO:0030500;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of Notch signaling pathway#GO:0045747;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;positive regulation of signal transduction#GO:0009967;regulation of multicellular organismal development#GO:2000026;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011872.1|UniProtKB=W5N1U0 W5N1U0 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA glutathione transferase activity#GO:0004364;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014785.1|UniProtKB=W5NC49 W5NC49 PTHR13902:SF47 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;protein serine/threonine kinase activity#GO:0004674;molecular function inhibitor activity#GO:0140678;protein kinase activity#GO:0004672;channel regulator activity#GO:0016247;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;chemical homeostasis#GO:0048878;regulation of metal ion transport#GO:0010959;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;homeostatic process#GO:0042592;negative regulation of biological process#GO:0048519;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014046.1|UniProtKB=W5N9K4 W5N9K4 PTHR12027:SF78 WNT RELATED PROTEIN WNT-7A receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;Wnt signaling pathway#GO:0016055;regulation of cell communication#GO:0010646;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;system development#GO:0048731;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;regulation of JNK cascade#GO:0046328;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;positive regulation of signaling#GO:0023056;cell fate commitment#GO:0045165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 LEPOC|Ensembl=ENSLOCG00000016141.1|UniProtKB=W5NGY1 W5NGY1 PTHR45787:SF7 LD11652P LIM DOMAIN ONLY PROTEIN 3 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000017419.1|UniProtKB=W5NLL5 W5NLL5 PTHR23428:SF77 HISTONE H2B HISTONE H2B TYPE 1-A chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000002933.1|UniProtKB=W5M4Z1 W5M4Z1 PTHR19331:SF439 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING GROUP B PROTEIN cargo receptor activity#GO:0038024 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003822.1|UniProtKB=W5M857 W5M857 PTHR21231:SF3 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 2 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;protein-binding activity modulator#PC00095;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000015192.1|UniProtKB=W5NDI9 W5NDI9 PTHR19308:SF33 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN START DOMAIN-CONTAINING PROTEIN 10 LEPOC|Ensembl=ENSLOCG00000000830.1|UniProtKB=W5LXR7 W5LXR7 PTHR11422:SF16 T-CELL SURFACE GLYCOPROTEIN CD4 DIVERSE IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 3.3 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007271.1|UniProtKB=W5MKA5 W5MKA5 PTHR19944:SF99 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ BETA 1 CHAIN antigen binding#GO:0003823;peptide binding#GO:0042277;binding#GO:0005488;protein-containing complex binding#GO:0044877 protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;positive regulation of leukocyte activation#GO:0002696;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of cell adhesion#GO:0045785;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;positive regulation of cellular process#GO:0048522;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773 major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000018210.1|UniProtKB=W5NNV2 W5NNV2 PTHR19290:SF86 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;eye development#GO:0001654;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;sensory system development#GO:0048880;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;camera-type eye development#GO:0043010;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000005495.1|UniProtKB=W5ME27 W5ME27 PTHR12844:SF10 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>CNKSR1#P07029 LEPOC|Ensembl=ENSLOCG00000017905.1|UniProtKB=W5NMZ9 W5NMZ9 PTHR31746:SF2 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229A LEPOC|Ensembl=ENSLOCG00000006445.1|UniProtKB=W5MHC5 W5MHC5 PTHR13235:SF2 SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000016292.1|UniProtKB=W5NHJ7 W5NHJ7 PTHR13962:SF19 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000000236.1|UniProtKB=W5LVV6 W5LVV6 PTHR13962:SF17 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000001012.1|UniProtKB=W5LYD1 W5LYD1 PTHR24413:SF91 SPECKLE-TYPE POZ PROTEIN SPECKLE-TYPE POZ PROTEIN-LIKE ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000006158.1|UniProtKB=W5MGC8 W5MGC8 PTHR15039:SF11 DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;mannosyltransferase complex#GO:0031501;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000800.1|UniProtKB=W5LXM9 W5LXM9 PTHR16222:SF24 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLHYDROLASE ARH3 catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 response to stress#GO:0006950;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;metabolic process#GO:0008152;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;macromolecule metabolic process#GO:0043170;response to reactive oxygen species#GO:0000302;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;nucleus#GO:0005634 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004229.1|UniProtKB=W5M9J9 W5M9J9 PTHR10201:SF166 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-19 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000013708.1|UniProtKB=W5N8E1 W5N8E1 PTHR48068:SF4 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;SAGA complex#GO:0000124;chromatin#GO:0000785;acetyltransferase complex#GO:1902493;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transferase complex#GO:1990234;peptidase complex#GO:1905368;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 LEPOC|Ensembl=ENSLOCG00000002966.1|UniProtKB=W5M546 W5M546 PTHR44227:SF3 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC4 glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;biosynthetic process#GO:0009058;biological regulation#GO:0065007;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;protein O-linked glycosylation via mannose#GO:0035269;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to unfolded protein#GO:0006986;protein metabolic process#GO:0019538 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000010468.1|UniProtKB=W5MWR9 W5MWR9 PTHR10819:SF3 PHOSPHOTRIESTERASE-RELATED N-ACETYLTAURINE HYDROLASE metabolite interconversion enzyme#PC00262;esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000009258.1|UniProtKB=W5MSD2 W5MSD2 PTHR20951:SF2 C13ORF1 PROTEIN-RELATED SPRY DOMAIN-CONTAINING PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000011327.1|UniProtKB=W5MZV5 W5MZV5 PTHR19282:SF203 TETRASPANIN TETRASPANIN-13 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002669.1|UniProtKB=W5M429 W5M429 PTHR22662:SF0 TIRAP TOLL_INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN Toll receptor signaling pathway#P00054>TIRAP#P01350 LEPOC|Ensembl=ENSLOCG00000006179.1|UniProtKB=W5MGH3 W5MGH3 PTHR16943:SF11 2-METHYLCITRATE DEHYDRATASE-RELATED CIS-ACONITATE DECARBOXYLASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;lyase activity#GO:0016829 regulation of response to external stimulus#GO:0032101;negative regulation of innate immune response#GO:0045824;negative regulation of response to external stimulus#GO:0032102;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of response to external stimulus#GO:0032103;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;oxoacid metabolic process#GO:0043436;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of innate immune response#GO:0045088;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;fatty acid metabolic process#GO:0006631;regulation of response to stress#GO:0080134;lipid metabolic process#GO:0006629;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;regulation of response to biotic stimulus#GO:0002831;primary metabolic process#GO:0044238;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;negative regulation of immune response#GO:0050777;regulation of immune response#GO:0050776 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 lyase#PC00144;dehydratase#PC00091;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015891.1|UniProtKB=W5NG11 W5NG11 PTHR10684:SF1 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 1 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712 positive regulation of transcription by RNA polymerase II#GO:0045944;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to chemical stimulus#GO:0070887;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000007191.1|UniProtKB=W5MJZ3 W5MJZ3 PTHR24230:SF59 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 84 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004304.1|UniProtKB=W5M9T6 W5M9T6 PTHR47220:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 25 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 25 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006573.1|UniProtKB=W5MHS7 W5MHS7 PTHR17469:SF11 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN ITPRID2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000016500.1|UniProtKB=W5NIC2 W5NIC2 PTHR16021:SF25 MANSC DOMAIN CONTAINING PROTEIN 1 MANSC DOMAIN CONTAINING 4 LEPOC|Ensembl=ENSLOCG00000006686.1|UniProtKB=W5MI63 W5MI63 PTHR19139:SF177 AQUAPORIN TRANSPORTER AQUAPORIN 14 channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;passive transmembrane transporter activity#GO:0022803 transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;water transport#GO:0006833;fluid transport#GO:0042044 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010591.1|UniProtKB=W5MX62 W5MX62 PTHR11711:SF163 ADP RIBOSYLATION FACTOR-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM23 carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 membrane#GO:0016020;lysosomal membrane#GO:0005765;cytoplasm#GO:0005737;vacuole#GO:0005773;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000004230.1|UniProtKB=W5M9J6 W5M9J6 PTHR23136:SF13 TAX1-BINDING PROTEIN 3-RELATED ST6 N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 3 LEPOC|Ensembl=ENSLOCG00000017383.1|UniProtKB=W5NLH9 W5NLH9 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007899.1|UniProtKB=W5MMI4 W5MMI4 PTHR10201:SF340 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-21 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000013789.1|UniProtKB=W5N8P6 W5N8P6 PTHR46599:SF9 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED 4-RELATED viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000008268.1|UniProtKB=W5MNT5 W5MNT5 PTHR23123:SF3 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 2A catalytic activity#GO:0003824;histone demethylase activity#GO:0032452;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457;histone modifying activity#GO:0140993 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000013651.1|UniProtKB=W5N875 W5N875 PTHR10177:SF184 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234 cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000002736.1|UniProtKB=W5M4B0 W5M4B0 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787 metabolic process#GO:0008152;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 LEPOC|Ensembl=ENSLOCG00000015299.1|UniProtKB=W5NDW9 W5NDW9 PTHR24347:SF403 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT BETA binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;regulation of neuronal synaptic plasticity#GO:0048168;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008;regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051 cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;neuron projection#GO:0043005;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;postsynaptic density#GO:0014069;axon#GO:0030424 non-receptor serine/threonine protein kinase#PC00167 Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Gonadotropin-releasing hormone receptor pathway#P06664>Ca/CaMK II#P06735 LEPOC|Ensembl=ENSLOCG00000008989.1|UniProtKB=W5MRE5 W5MRE5 PTHR10153:SF46 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL POTASSIUM CALCIUM-ACTIVATED CHANNEL SUBFAMILY N MEMBER 2 transporter activity#GO:0005215;calmodulin binding#GO:0005516;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;calcium-activated potassium channel activity#GO:0015269;monoatomic ion-gated channel activity#GO:0022839;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805 plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;cell body#GO:0044297;membrane#GO:0016020 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000006451.1|UniProtKB=W5MHE0 W5MHE0 PTHR22781:SF14 DELTA ADAPTIN-RELATED AP-3 COMPLEX SUBUNIT DELTA-1 membrane organization#GO:0061024;cytoskeleton-dependent intracellular transport#GO:0030705;synaptic vesicle recycling#GO:0036465;vesicle localization#GO:0051648;macromolecule localization#GO:0033036;synaptic vesicle membrane organization#GO:0048499;axo-dendritic transport#GO:0008088;vesicle cytoskeletal trafficking#GO:0099518;anterograde synaptic vesicle transport#GO:0048490;intracellular protein localization#GO:0008104;vesicle budding from membrane#GO:0006900;establishment of protein localization to organelle#GO:0072594;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;microtubule-based movement#GO:0007018;protein localization to organelle#GO:0033365;anterograde axonal transport#GO:0008089;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;protein localization to vacuole#GO:0072665;axonal transport#GO:0098930;endosome to lysosome transport#GO:0008333;organelle localization#GO:0051640;endomembrane system organization#GO:0010256;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;synaptic vesicle transport#GO:0048489;protein targeting to vacuole#GO:0006623;endosomal transport#GO:0016197;microtubule-based process#GO:0007017;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;establishment of protein localization to vacuole#GO:0072666;establishment of organelle localization#GO:0051656;protein targeting#GO:0006605;protein localization to lysosome#GO:0061462;cellular component organization#GO:0016043;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;lysosomal transport#GO:0007041 axon terminus#GO:0043679;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;endomembrane system#GO:0012505;axon#GO:0030424;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;vesicle#GO:0031982;neuron projection terminus#GO:0044306;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;neuron projection#GO:0043005;presynapse#GO:0098793;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;coated membrane#GO:0048475;intracellular vesicle#GO:0097708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009159.1|UniProtKB=W5MS15 W5MS15 PTHR12131:SF31 ATP-DEPENDENT RNA AND DNA HELICASE ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001058.1|UniProtKB=W5LYI5 W5LYI5 PTHR23349:SF40 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BHLH DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000009296.1|UniProtKB=W5MSI5 W5MSI5 PTHR13383:SF11 RIBONUCLEASE H2 SUBUNIT B RIBONUCLEASE H2 SUBUNIT B RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000003757.1|UniProtKB=W5M7X1 W5M7X1 PTHR12482:SF3 LIPASE ROG1-RELATED-RELATED PROTEIN FAM135B hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000014745.1|UniProtKB=W5NBZ3 W5NBZ3 PTHR24228:SF56 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN-RELATED RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000016167.1|UniProtKB=W5NH15 W5NH15 PTHR46227:SF3 GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;endosome to plasma membrane protein transport#GO:0099638;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;protein localization to synapse#GO:0035418;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;endocytic recycling#GO:0032456;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;regulation of biological quality#GO:0065008;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;protein localization to cell junction#GO:1902414 LEPOC|Ensembl=ENSLOCG00000011330.1|UniProtKB=W5MZW6 W5MZW6 PTHR11385:SF14 SERUM ALBUMIN-RELATED ALBUMIN-RELATED binding#GO:0005488;small molecule binding#GO:0036094 response to nutrient levels#GO:0031667;response to stimulus#GO:0050896 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000005024.1|UniProtKB=W5MCD7 W5MCD7 PTHR12002:SF177 CLAUDIN CLAUDIN-10 transporter activity#GO:0005215;paracellular tight junction channel activity#GO:0160187 cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;transport#GO:0006810;paracellular transport#GO:0160184;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell junction organization#GO:0034330 apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000003187.1|UniProtKB=W5M5V9 W5M5V9 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011359.1|UniProtKB=W5N001 W5N001 PTHR47992:SF274 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE MN(2+)-DEPENDENT 1K hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000003334.1|UniProtKB=W5M6D2 W5M6D2 PTHR46661:SF2 E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZNRF1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000017764.1|UniProtKB=W5NMK9 W5NMK9 PTHR16155:SF3 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007806.1|UniProtKB=W5MM70 W5MM70 PTHR13531:SF14 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 17 cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000005176.1|UniProtKB=W5MCX4 W5MCX4 PTHR10915:SF7 SYNDECAN SYNDECAN-3 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007591.1|UniProtKB=W5MLF2 W5MLF2 PTHR24327:SF23 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development ending in birth or egg hatching#GO:0009792;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000005140.1|UniProtKB=W5MCS8 W5MCS8 PTHR15326:SF9 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC SPERMATOGENESIS-ASSOCIATED PROTEIN 2 PUB-LIKE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000007467.1|UniProtKB=W5ML08 W5ML08 PTHR47194:SF3 SORTING NEXIN-29-RELATED SORTING NEXIN-29 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000298.1|UniProtKB=W5LW21 W5LW21 PTHR10337:SF6 SHC TRANSFORMING PROTEIN CENTROSOMAL PROTEIN OF 152 KDA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle assembly#GO:0070925;centriole replication#GO:0007099;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015288.1|UniProtKB=W5NDV6 W5NDV6 PTHR23164:SF30 EARLY ENDOSOME ANTIGEN 1 EARLY ENDOSOME ANTIGEN 1 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 endocytosis#GO:0006897;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004206.1|UniProtKB=W5M9H1 W5M9H1 PTHR45891:SF4 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 3 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013442.1|UniProtKB=W5N7I0 W5N7I0 PTHR12250:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS N GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000014135.1|UniProtKB=W5N9V2 W5N9V2 PTHR47266:SF33 ENDONUCLEASE-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000000938.1|UniProtKB=W5LY41 W5LY41 EIF3F PTHR10540:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F hydrolase activity#GO:0016787;protein binding#GO:0005515;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005;binding#GO:0005488;peptidase activity#GO:0008233;translation initiation factor activity#GO:0003743;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;translation initiation factor binding#GO:0031369;translation factor activity#GO:0180051;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000014654.1|UniProtKB=W5NBM9 W5NBM9 PTHR10015:SF274 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000003343.1|UniProtKB=W5M6I7 W5M6I7 PTHR23007:SF5 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;protein kinase binding#GO:0019901;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;transferase activity#GO:0016740 signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane microdomain#GO:0098857;membrane raft#GO:0045121;membrane#GO:0016020 ligase#PC00142 EGF receptor signaling pathway#P00018>c-Cbl#P00544 LEPOC|Ensembl=ENSLOCG00000006389.1|UniProtKB=W5MHA2 W5MHA2 PTHR11566:SF225 DYNAMIN INTERFERON-INDUCED GTP-BINDING PROTEIN MX-RELATED catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;microtubule binding#GO:0008017;GTPase activity#GO:0003924;protein binding#GO:0005515;hydrolase activity#GO:0016787 cellular localization#GO:0051641;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;endocytosis#GO:0006897;establishment of organelle localization#GO:0051656;defense response to virus#GO:0051607;cellular component organization#GO:0016043;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of vesicle localization#GO:0051650;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;synaptic vesicle transport#GO:0048489;localization#GO:0051179;response to virus#GO:0009615;organelle localization#GO:0051640;response to external biotic stimulus#GO:0043207;synaptic vesicle endocytosis#GO:0048488;response to external stimulus#GO:0009605;vesicle budding from membrane#GO:0006900;defense response#GO:0006952;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;response to other organism#GO:0051707;synaptic vesicle recycling#GO:0036465;vesicle localization#GO:0051648 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;nucleus#GO:0005634;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001051.1|UniProtKB=W5LYH5 W5LYH5 PTHR24103:SF700 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM7 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016707.1|UniProtKB=W5NJ30 W5NJ30 PTHR18874:SF10 CMF/LEK/CENP CELL DIVISION-RELATED CENTROMERE PROTEIN F LEPOC|Ensembl=ENSLOCG00000015907.1|UniProtKB=W5NG28 W5NG28 PTHR10969:SF50 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 GAMMA phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289;ubiquitin protein ligase binding#GO:0031625 cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular response to nutrient levels#GO:0031669;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane#GO:0016020;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000013728.1|UniProtKB=W5N8H0 W5N8H0 PTHR13498:SF3 SPERM ASSOCIATED ANTIGEN 7 SPERM-ASSOCIATED ANTIGEN 7 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002224.1|UniProtKB=W5M2I0 W5M2I0 PTHR31056:SF1 TRANSMEMBRANE PROTEIN 179B TRANSMEMBRANE PROTEIN 179B LEPOC|Ensembl=ENSLOCG00000014164.1|UniProtKB=W5N9Z0 W5N9Z0 PTHR16875:SF0 SELENOPROTEIN K SELENOPROTEIN K regulation of signaling#GO:0023051;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000010866.1|UniProtKB=W5MY54 W5MY54 PTHR26451:SF470 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016274.1|UniProtKB=W5NHG3 W5NHG3 PTHR14667:SF2 BARDET-BIEDL SYNDROME 10 PROTEIN BBSOME COMPLEX ASSEMBLY PROTEIN BBS10 chaperone-mediated protein complex assembly#GO:0051131;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607 LEPOC|Ensembl=ENSLOCG00000006435.1|UniProtKB=W5MHB7 W5MHB7 PTHR24103:SF654 E3 UBIQUITIN-PROTEIN LIGASE TRIM SI:DKEY-29P10.4 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012250.1|UniProtKB=W5N366 W5N366 PTHR11202:SF18 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 negative regulation of response to stimulus#GO:0048585;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005453.1|UniProtKB=W5MDX1 W5MDX1 PTHR23065:SF18 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 3 phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 regulation of endocytosis#GO:0030100;cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;regulation of transport#GO:0051049;regulation of localization#GO:0032879;organelle organization#GO:0006996;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;cytoskeleton organization#GO:0007010;membrane organization#GO:0061024 plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000013116.1|UniProtKB=W5N6A3 W5N6A3 PTHR12751:SF6 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 1 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;stress fiber assembly#GO:0043149;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;contractile actin filament bundle assembly#GO:0030038 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000008488.1|UniProtKB=W5MPM2 W5MPM2 PTHR10859:SF91 GLYCOSYL TRANSFERASE DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000013898.1|UniProtKB=W5N927 W5N927 PTHR15837:SF6 RAN GUANINE NUCLEOTIDE RELEASE FACTOR RAN GUANINE NUCLEOTIDE RELEASE FACTOR molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;transporter regulator activity#GO:0141108;enzyme binding#GO:0019899;transmembrane transporter binding#GO:0044325;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488 circulatory system process#GO:0003013;regulation of membrane potential#GO:0042391;regulation of biological quality#GO:0065008;heart contraction#GO:0060047;system process#GO:0003008;heart process#GO:0003015;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000000223.1|UniProtKB=W5LVU1 W5LVU1 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016203.1|UniProtKB=W5NH63 W5NH63 PTHR16188:SF6 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14C enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;protein serine/threonine phosphatase inhibitor activity#GO:0004865;phosphatase regulator activity#GO:0019208;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000009633.1|UniProtKB=W5MTR6 W5MTR6 PTHR12995:SF3 FI21814P1 TRANSMEMBRANE PROTEIN 39A negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of catabolic process#GO:0009895;regulation of autophagosome assembly#GO:2000785;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;regulation of macroautophagy#GO:0016241;negative regulation of cellular process#GO:0048523;regulation of autophagosome maturation#GO:1901096;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein-containing complex disassembly#GO:0043244;negative regulation of macroautophagy#GO:0016242;regulation of organelle assembly#GO:1902115 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 LEPOC|Ensembl=ENSLOCG00000009735.1|UniProtKB=W5MU29 W5MU29 PTHR13343:SF21 CREG1 PROTEIN PROTEIN CREG1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003338.1|UniProtKB=W5M6D4 W5M6D4 PTHR16070:SF1 PROTEIN FAM222A-RELATED PROTEIN FAM222B LEPOC|Ensembl=ENSLOCG00000018211.1|UniProtKB=W5NNV3 W5NNV3 PTHR26451:SF886 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004774.1|UniProtKB=W5MBH5 W5MBH5 PTHR45716:SF10 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 transport#GO:0006810;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000012573.1|UniProtKB=W5N4B8 W5N4B8 PTHR14485:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 23 TETRATRICOPEPTIDE REPEAT PROTEIN 23-LIKE LEPOC|Ensembl=ENSLOCG00000003554.1|UniProtKB=W5M748 W5M748 PTHR47011:SF1 CD226 ANTIGEN CD226 ANTIGEN cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;positive regulation of signaling#GO:0023056;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;positive regulation of adaptive immune response#GO:0002821;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 LEPOC|Ensembl=ENSLOCG00000002824.1|UniProtKB=W5M4M5 W5M4M5 PTHR15741:SF41 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR CARBOHYDRATE-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009743.1|UniProtKB=W5MU47 W5MU47 PTHR46583:SF1 REGULATOR OF G-PROTEIN SIGNALING 22 REGULATOR OF G PROTEIN SIGNALING 22 protein binding#GO:0005515;binding#GO:0005488 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000008209.1|UniProtKB=W5MNK8 W5MNK8 PTHR48071:SF37 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009438.1|UniProtKB=W5MT17 W5MT17 PTHR46806:SF3 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;wound healing#GO:0042060;response to stress#GO:0006950;response to wounding#GO:0009611 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000005678.1|UniProtKB=W5MES0 W5MES0 PTHR11675:SF47 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 13 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000003578.1|UniProtKB=W5M785 W5M785 PTHR46823:SF2 CALCINEURIN B HOMOLOGOUS PROTEIN 3 CALCINEURIN B HOMOLOGOUS PROTEIN 3 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cation binding#GO:0043169;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;regulation of developmental process#GO:0050793;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;localization within membrane#GO:0051668;regulation of myeloid cell differentiation#GO:0045637;regulation of hemopoiesis#GO:1903706;localization#GO:0051179;cellular localization#GO:0051641;positive regulation of biological process#GO:0048518;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of cell development#GO:0060284;macromolecule localization#GO:0033036;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;regulation of cell adhesion#GO:0030155;positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015729.1|UniProtKB=W5NFF5 W5NFF5 PTHR24064:SF461 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000016828.1|UniProtKB=W5NJJ4 W5NJJ4 PTHR45702:SF6 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 17 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;biological regulation#GO:0065007;proteolysis#GO:0006508;cell communication#GO:0007154;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>TACE#P00147;Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-amyloid secretase pathway#P00003>TACE#P00092 LEPOC|Ensembl=ENSLOCG00000000517.1|UniProtKB=W5LWR2 W5LWR2 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000012542.1|UniProtKB=W5N488 W5N488 PTHR28553:SF1 NEUROPEPTIDE B NEUROPEPTIDE B protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;feeding behavior#GO:0007631;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000012699.1|UniProtKB=W5N4S4 W5N4S4 PTHR46392:SF1 DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE DUAL SERINE_THREONINE AND TYROSINE PROTEIN KINASE positive regulation of signal transduction#GO:0009967;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;negative regulation of cellular process#GO:0048523;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;cellular response to fibroblast growth factor stimulus#GO:0044344;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of ERK1 and ERK2 cascade#GO:0070372 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002265.1|UniProtKB=W5M2Q9 W5M2Q9 PTHR46303:SF3 VWFC DOMAIN-CONTAINING PROTEIN CHORDIN-LIKE PROTEIN 2 binding#GO:0005488;cytokine binding#GO:0019955;protein binding#GO:0005515 negative regulation of response to stimulus#GO:0048585;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987;cellular developmental process#GO:0048869;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013351.1|UniProtKB=W5N745 W5N745 PTHR24055:SF171 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 6 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>MEK#P01402;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interleukin signaling pathway#P00036>ERK#P00965;Integrin signalling pathway#P00034>ERK#P00907 LEPOC|Ensembl=ENSLOCG00000011006.1|UniProtKB=W5MYQ2 W5MYQ2 PTHR21501:SF4 PROTEIN FAM-161 PROTEIN FAM161B cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840 LEPOC|Ensembl=ENSLOCG00000010860.1|UniProtKB=W5MY50 W5MY50 PTHR43011:SF1 IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL metal ion binding#GO:0046872;cation binding#GO:0043169;iron-sulfur cluster binding#GO:0051536;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;iron ion binding#GO:0005506 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;iron-sulfur cluster assembly#GO:0016226;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004820.1|UniProtKB=W5MBM8 W5MBM8 PTHR31854:SF2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004444.1|UniProtKB=W5MAA3 W5MAA3 PTHR16206:SF9 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004324.1|UniProtKB=W5M9W0 W5M9W0 PTHR16213:SF78 SELENOPROTEIN N SELENOPROTEIN N anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;regulation of transmembrane transport#GO:0034762;muscle cell differentiation#GO:0042692;regulation of metal ion transport#GO:0010959;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;regulation of monoatomic cation transmembrane transport#GO:1904062;developmental process#GO:0032502;monoatomic cation homeostasis#GO:0055080;cellular developmental process#GO:0048869;skeletal muscle tissue development#GO:0007519;regulation of monoatomic ion transport#GO:0043269;tissue development#GO:0009888;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;calcium ion homeostasis#GO:0055074;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;inorganic ion homeostasis#GO:0098771;striated muscle cell development#GO:0055002;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cell development#GO:0048468;muscle organ development#GO:0007517;striated muscle tissue development#GO:0014706;chemical homeostasis#GO:0048878;animal organ development#GO:0048513;regulation of transport#GO:0051049;regulation of localization#GO:0032879;striated muscle cell differentiation#GO:0051146;regulation of release of sequestered calcium ion into cytosol#GO:0051279;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000000513.1|UniProtKB=W5LWQ8 W5LWQ8 PTHR14186:SF20 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED IGFBP DOMAIN-CONTAINING PROTEIN ISOFORM X1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000003789.1|UniProtKB=W5M817 W5M817 PTHR12246:SF28 PALMITOYLTRANSFERASE ZDHHC16 PALMITOYLTRANSFERASE ZDHHC16 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;multicellular organismal process#GO:0032501;heart development#GO:0007507;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cellular response to stress#GO:0033554;developmental process#GO:0032502;DNA damage response#GO:0006974;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002001.1|UniProtKB=W5M1U2 W5M1U2 PTHR18966:SF171 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 4 gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic cation transmembrane transporter activity#GO:0008324;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;signaling receptor activity#GO:0038023;carboxylic acid transmembrane transporter activity#GO:0046943;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium ion transmembrane transporter activity#GO:0015079;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081 cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495 transmembrane signal receptor#PC00197 Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>KA4#P01001;Ionotropic glutamate receptor pathway#P00037>KA#P01026 LEPOC|Ensembl=ENSLOCG00000017795.1|UniProtKB=W5NMP0 W5NMP0 PTHR10704:SF5 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 7 catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 amino sugar metabolic process#GO:0006040;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;sulfur compound metabolic process#GO:0006790;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013889.1|UniProtKB=W5N919 W5N919 PTHR24412:SF74 KELCH PROTEIN KELCH-LIKE PROTEIN 4 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007633.1|UniProtKB=W5MLK3 W5MLK3 PTHR46349:SF4 CINGULIN-LIKE PROTEIN 1-RELATED CINGULIN protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 cell-cell junction#GO:0005911;apical junction complex#GO:0043296;tight junction#GO:0070160;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell junction#GO:0030054;anchoring junction#GO:0070161 LEPOC|Ensembl=ENSLOCG00000002854.1|UniProtKB=W5M522 W5M522 PTHR10574:SF409 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;circulatory system development#GO:0072359;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;eye development#GO:0001654;axonogenesis#GO:0007409;neuron development#GO:0048666;sensory system development#GO:0048880;neuron projection development#GO:0031175;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;vasculature development#GO:0001944;cell projection morphogenesis#GO:0048858;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;visual system development#GO:0150063;camera-type eye development#GO:0043010;anatomical structure development#GO:0048856;system development#GO:0048731;axon development#GO:0061564;axon guidance#GO:0007411;tissue development#GO:0009888;multicellular organismal process#GO:0032501;tube development#GO:0035295;plasma membrane bounded cell projection organization#GO:0120036;sensory organ development#GO:0007423;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000016784.1|UniProtKB=W5NJE2 W5NJE2 PTHR11782:SF99 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 6 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleoside diphosphate metabolic process#GO:0009132 membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000005008.1|UniProtKB=W5MCB9 W5MCB9 PTHR12002:SF177 CLAUDIN CLAUDIN-10 paracellular tight junction channel activity#GO:0160187;transporter activity#GO:0005215 paracellular transport#GO:0160184;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;cell-cell junction organization#GO:0045216;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000007954.1|UniProtKB=W5MMQ2 W5MMQ2 PTHR10574:SF28 NETRIN/LAMININ-RELATED NETRIN-G1 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;axon development#GO:0061564;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;tissue development#GO:0009888;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 LEPOC|Ensembl=ENSLOCG00000001748.1|UniProtKB=W5M0X2 W5M0X2 PTHR45679:SF1 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ALPHA-1,2-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;protein catabolic process#GO:0030163;response to unfolded protein#GO:0006986;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;macromolecule metabolic process#GO:0043170;endoplasmic reticulum unfolded protein response#GO:0030968;carbohydrate derivative metabolic process#GO:1901135;biological regulation#GO:0065007;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;protein metabolic process#GO:0019538;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000009752.1|UniProtKB=W5MU57 W5MU57 PTHR28544:SF1 PROTEIN FAM45A-RELATED DENN DOMAIN-CONTAINING PROTEIN 10-RELATED binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 macromolecule localization#GO:0033036;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;establishment of protein localization#GO:0045184;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;regulation of localization#GO:0032879;regulation of transport#GO:0051049;intracellular protein localization#GO:0008104 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 LEPOC|Ensembl=ENSLOCG00000015074.1|UniProtKB=W5ND40 W5ND40 PTHR23211:SF0 TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN TGN38 TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN 2 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000137.1|UniProtKB=W5LVJ2 W5LVJ2 PTHR34072:SF66 ENZYMATIC POLYPROTEIN-RELATED REVERSE TRANSCRIPTASE LEPOC|Ensembl=ENSLOCG00000003222.1|UniProtKB=W5M5Z8 W5M5Z8 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 519 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015520.1|UniProtKB=W5NEP5 W5NEP5 PTHR46531:SF1 ZINC TRANSPORTER 6 ZINC TRANSPORTER 6 transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;metal ion transport#GO:0030001;zinc ion transport#GO:0006829 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002519.1|UniProtKB=W5M3J9 W5M3J9 PTHR11559:SF416 CARBOXYLESTERASE CARBOXYLESTERASE 3 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000005362.1|UniProtKB=W5MDK4 W5MDK4 PTHR12357:SF8 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 2 protein-RNA adaptor activity#GO:0140517;nucleic acid binding#GO:0003676;binding#GO:0005488;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;RNA binding#GO:0003723 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002049.1|UniProtKB=W5M211 W5M211 PTHR43982:SF1 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 protein-containing complex binding#GO:0044877;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;binding#GO:0005488;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843 negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of catabolic process#GO:0009894;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to stimulus#GO:0048585;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007;regulation of protein catabolic process#GO:0042176;regulation of cellular response to stress#GO:0080135;negative regulation of catabolic process#GO:0009895;negative regulation of biological process#GO:0048519;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of ERAD pathway#GO:1904292 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000012858.1|UniProtKB=W5N5B8 W5N5B8 PTHR23285:SF5 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3B RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002334.1|UniProtKB=W5M2Y9 W5M2Y9 PTHR24300:SF319 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 1 binding#GO:0005488;tetrapyrrole binding#GO:0046906;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017257.1|UniProtKB=W5NL36 W5NL36 PTHR11955:SF57 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, BRAIN fatty acid binding#GO:0005504;lipid binding#GO:0008289;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;organic acid binding#GO:0043177 establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid transport#GO:0006869;macromolecule localization#GO:0033036 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000009669.1|UniProtKB=W5MTV2 W5MTV2 PTHR35450:SF2 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN C1Q DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008213.1|UniProtKB=W5MNL2 W5MNL2 PTHR15628:SF1 RWD DOMAIN-CONTAINING PROTEIN 3 RWD DOMAIN-CONTAINING PROTEIN 3 positive regulation of response to stimulus#GO:0048584;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;positive regulation of intracellular signal transduction#GO:1902533;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 LEPOC|Ensembl=ENSLOCG00000011135.1|UniProtKB=W5MZ65 W5MZ65 PTHR10164:SF3 ISLET CELL AUTOANTIGEN 1 ISLET CELL AUTOANTIGEN 1 molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 cellular component organization or biogenesis#GO:0071840;regulation of secretion#GO:0051046;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;biological regulation#GO:0065007;membrane organization#GO:0061024 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000002987.1|UniProtKB=W5M558 W5M558 PTHR11818:SF13 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B3 structural molecule activity#GO:0005198 visual system development#GO:0150063;visual perception#GO:0007601;sensory perception of light stimulus#GO:0050953;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013390.1|UniProtKB=W5N795 W5N795 PTHR23268:SF28 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 27 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011179.1|UniProtKB=W5MZD1 W5MZD1 PTHR18945:SF786 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A ISOFORM X1-RELATED neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000005387.1|UniProtKB=W5MDN4 W5MDN4 PTHR42757:SF47 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED OPIOID-BINDING PROTEIN_CELL ADHESION MOLECULE PRECURSOR biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;cell adhesion#GO:0007155;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006018.1|UniProtKB=W5MFV9 W5MFV9 PTHR11675:SF36 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 15 catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000018118.1|UniProtKB=W5NNL0 W5NNL0 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000016236.1|UniProtKB=W5NHB0 W5NHB0 PTHR11843:SF0 40S RIBOSOMAL PROTEIN S12 SMALL RIBOSOMAL SUBUNIT PROTEIN ES12 cellular component biogenesis#GO:0044085;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;translation#GO:0006412;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000007285.1|UniProtKB=W5MKA9 W5MKA9 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002700.1|UniProtKB=W5M492 W5M492 PTHR12771:SF8 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 2 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;response to external stimulus#GO:0009605;organelle organization#GO:0006996;cellular process#GO:0009987;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;cytoskeleton organization#GO:0007010;cellular response to chemical stimulus#GO:0070887;actin filament-based process#GO:0030029;chemotaxis#GO:0006935;supramolecular fiber organization#GO:0097435;cell chemotaxis#GO:0060326;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>ELMO#P00917 LEPOC|Ensembl=ENSLOCG00000000863.1|UniProtKB=W5LXV2 W5LXV2 PTHR46317:SF7 HYDROLASE OF PHP SUPERFAMILY-RELATED PROTEIN DEOXYRIBONUCLEASE TATDN3 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010376.1|UniProtKB=W5MWF6 W5MWF6 PTHR21636:SF2 PROTEIN DOK-7 PROTEIN DOK-7 protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;neuromuscular junction development#GO:0007528;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 LEPOC|Ensembl=ENSLOCG00000000492.1|UniProtKB=W5LWX6 W5LWX6 PTHR48071:SF18 SRCR DOMAIN-CONTAINING PROTEIN SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN DMBT1 ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000007516.1|UniProtKB=W5ML66 W5ML66 PTHR10139:SF9 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520 response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;DNA recombination#GO:0006310;metabolic process#GO:0008152;double-strand break repair#GO:0006302;negative regulation of cell cycle#GO:0045786;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;signaling#GO:0023052;cellular response to stress#GO:0033554;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;telomere maintenance#GO:0000723;double-strand break repair via nonhomologous end joining#GO:0006303;mitotic DNA damage checkpoint signaling#GO:0044773;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;meiotic DNA double-strand break formation#GO:0042138;organelle organization#GO:0006996;negative regulation of mitotic cell cycle phase transition#GO:1901991;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;negative regulation of cell cycle G2/M phase transition#GO:1902750;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;biological regulation#GO:0065007;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;telomere organization#GO:0032200;regulation of G2/M transition of mitotic cell cycle#GO:0010389 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000018223.1|UniProtKB=W5NNW5 W5NNW5 PTHR24393:SF151 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 956 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017075.1|UniProtKB=W5NKE3 W5NKE3 PTHR10426:SF20 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN LIKE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 LEPOC|Ensembl=ENSLOCG00000015168.1|UniProtKB=W5NDF7 W5NDF7 PTHR12984:SF6 SCY1-RELATED S/T PROTEIN KINASE-LIKE SCY1-LIKE PROTEIN 2 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000015308.1|UniProtKB=W5NDX8 W5NDX8 PTHR13803:SF29 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24C ISOFORM X1 zinc ion binding#GO:0008270;SNARE binding#GO:0000149;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000015300.1|UniProtKB=W5NDW7 W5NDW7 PTHR45735:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010170.1|UniProtKB=W5MVN8 W5MVN8 PTHR45752:SF1 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 69 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010611.1|UniProtKB=W5MX96 W5MX96 PTHR13723:SF27 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 6 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000007569.1|UniProtKB=W5MLC4 W5MLC4 PTHR48015:SF32 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE 4 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408;positive regulation of apoptotic process#GO:0043065;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;hippo signaling#GO:0035329;negative regulation of signal transduction#GO:0009968;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001698.1|UniProtKB=W5M0Q5 W5M0Q5 PTHR11188:SF183 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000017213.1|UniProtKB=W5NKX3 W5NKX3 ADI1 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009005.1|UniProtKB=W5MRG6 W5MRG6 PTHR23347:SF7 COLORECTAL MUTANT CANCER PROTEIN MCC PROTEIN -RELATED COLORECTAL MUTANT CANCER PROTEIN ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000013905.1|UniProtKB=W5N933 W5N933 PTHR19446:SF487 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000016818.1|UniProtKB=W5NJI2 W5NJI2 PTHR45854:SF4 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000012312.1|UniProtKB=W5N3D8 W5N3D8 PTHR12626:SF3 PROGRAMMED CELL DEATH 4 PROGRAMMED CELL DEATH PROTEIN 4 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000011192.1|UniProtKB=W5MZD8 W5MZD8 PTHR22923:SF111 CEREBELLIN-RELATED C1Q AND TNF RELATED 6 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017528.1|UniProtKB=W5NLX4 W5NLX4 PTHR24232:SF20 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 1 peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of coagulation#GO:0050820;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of blood coagulation#GO:0030193;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of body fluid levels#GO:0050878;signaling#GO:0023052;regulation of wound healing#GO:0061041;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of response to wounding#GO:1903034;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of hemostasis#GO:1900046;positive regulation of response to stimulus#GO:0048584;regulation of coagulation#GO:0050818;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Angiogenesis#P00005>PAR#P00192;Blood coagulation#P00011>PAR-1#P00404 LEPOC|Ensembl=ENSLOCG00000002132.1|UniProtKB=W5M284 W5M284 PTHR23280:SF8 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN 3 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000018141.1|UniProtKB=W5NNN3 W5NNN3 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000009345.1|UniProtKB=W5MSP1 W5MSP1 PTHR13172:SF5 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial intermembrane space#GO:0005758;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial envelope#GO:0005740;membrane-enclosed lumen#GO:0031974 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012582.1|UniProtKB=W5N4D3 W5N4D3 PTHR14074:SF7 HELICASE WITH DEATH DOMAIN-RELATED ATP-DEPENDENT RNA HELICASE DHX58 metal ion binding#GO:0046872;RNA binding#GO:0003723;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;nucleic acid binding#GO:0003676;ion binding#GO:0043167;transition metal ion binding#GO:0046914;double-stranded RNA binding#GO:0003725;single-stranded RNA binding#GO:0003727;zinc ion binding#GO:0008270 innate immune response-activating signaling pathway#GO:0002758;antiviral innate immune response#GO:0140374;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;intracellular receptor signaling pathway#GO:0030522;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;response to virus#GO:0009615;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;defense response to virus#GO:0051607;negative regulation of biological process#GO:0048519;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;negative regulation of signal transduction#GO:0009968;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005348.1|UniProtKB=W5MDI3 W5MDI3 PTHR15950:SF22 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 2B regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000006833.1|UniProtKB=W5MIQ7 W5MIQ7 PTHR13069:SF21 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 TRNA (CARBOXYMETHYLURIDINE(34)-5-O)-METHYLTRANSFERASE ALKBH8 binding#GO:0005488;nucleic acid binding#GO:0003676;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175 cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;macromolecule modification#GO:0043412 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003065.1|UniProtKB=W5M5G6 W5M5G6 PTHR45789:SF1 FI18025P1 TRANSCRIPTION FACTOR SOX-6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000010762.1|UniProtKB=W5MXS6 W5MXS6 PTHR11592:SF41 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 modified amino acid metabolic process#GO:0006575;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;hydrogen peroxide metabolic process#GO:0042743;cellular response to chemical stimulus#GO:0070887;glutathione metabolic process#GO:0006749;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;response to stress#GO:0006950;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000004345.1|UniProtKB=W5M9Y6 W5M9Y6 PTHR43489:SF6 ISOMERASE HYDROXYPYRUVATE ISOMERASE-RELATED intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;glyoxylate metabolic process#GO:0046487;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;isomerase#PC00135 LEPOC|Ensembl=ENSLOCG00000014611.1|UniProtKB=W5NBH2 W5NBH2 PTHR10155:SF18 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 9 ISOFORM X1 cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789 kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000007266.1|UniProtKB=W5MK77 W5MK77 PTHR16476:SF4 FAMILY WITH SEQUENCE SIMILARITY 216 MEMBER A PROTEIN FAM216A ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000002430.1|UniProtKB=W5M392 W5M392 PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;amidase activity#GO:0004040;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000006634.1|UniProtKB=W5MI05 W5MI05 PTHR42908:SF28 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR 2 ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;hydrolase activity#GO:0016787;ribonucleoprotein complex binding#GO:0043021;GTPase activity#GO:0003924;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000004432.1|UniProtKB=W5MA95 W5MA95 PTHR22969:SF13 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT ALPHA kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cytokine-mediated signaling pathway#GO:0019221;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;response to tumor necrosis factor#GO:0034612;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;response to cytokine#GO:0034097 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 B cell activation#P00010>IKK#P00397;T cell activation#P00053>IKK#P01330;PDGF signaling pathway#P00047>Ikk#P01146;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871;Toll receptor signaling pathway#P00054>IKKalpha#P01345;Apoptosis signaling pathway#P00006>IKK#P00313;Interleukin signaling pathway#P00036>Ikk#P00968 LEPOC|Ensembl=ENSLOCG00000013649.1|UniProtKB=W5N892 W5N892 PTHR11219:SF65 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-3 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;synapse organization#GO:0050808;system development#GO:0048731;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;synaptic membrane adhesion#GO:0099560;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154 cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978 LEPOC|Ensembl=ENSLOCG00000005206.1|UniProtKB=W5MD09 W5MD09 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000014397.1|UniProtKB=W5NAR7 W5NAR7 PTHR11188:SF16 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 4 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003613.1|UniProtKB=W5M7E5 W5M7E5 PTHR15683:SF6 SCAFFOLD ATTACHMENT FACTOR B-RELATED SCAFFOLD ATTACHMENT FACTOR B-RELATED intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008975.1|UniProtKB=W5MRC8 W5MRC8 PTHR24291:SF6 CYTOCHROME P450 FAMILY 4 STEROL 26-HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;vitamin D metabolic process#GO:0042359;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>1alpha-Hydroxylase#P04603 LEPOC|Ensembl=ENSLOCG00000007738.1|UniProtKB=W5MLZ7 W5MLZ7 PTHR10130:SF2 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR signal sequence receptor activity#GO:0005048;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 peroxisome organization#GO:0007031;protein transport#GO:0015031;peroxisomal transport#GO:0043574;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;cellular component organization#GO:0016043;protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036 organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006248.1|UniProtKB=W5MGP3 W5MGP3 PTHR12271:SF49 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE 4 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;regulation of mRNA metabolic process#GO:1903311;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000014152.1|UniProtKB=W5N9Y7 W5N9Y7 PTHR24416:SF52 TYROSINE-PROTEIN KINASE RECEPTOR PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein kinase activity#GO:0004672;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199 animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cell surface receptor signaling pathway#GO:0007166;embryo development#GO:0009790;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;skeletal system development#GO:0001501;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;developmental process#GO:0032502;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell migration#GO:0016477;positive regulation of cellular process#GO:0048522;skeletal system morphogenesis#GO:0048705;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell motility#GO:0048870;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 Angiogenesis#P00005>PDGFR#P00230;PDGF signaling pathway#P00047>PDGF receptor A#P01158 LEPOC|Ensembl=ENSLOCG00000001426.1|UniProtKB=W5LZR9 W5LZR9 PTHR24254:SF9 PROTHROMBIN INACTIVE SERINE PROTEASE PAMR1 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016521.1|UniProtKB=W5NIE7 W5NIE7 PTHR22739:SF22 STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED ACTIN-BINDING RHO-ACTIVATING PROTEIN positive regulation of signal transduction#GO:0009967;positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of Rho protein signal transduction#GO:0035023;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of small GTPase mediated signal transduction#GO:0051056 contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017 LEPOC|Ensembl=ENSLOCG00000005370.1|UniProtKB=W5MDL0 W5MDL0 PTHR22791:SF31 RING-TYPE DOMAIN-CONTAINING PROTEIN IM:7152348 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000006723.1|UniProtKB=W5MIB8 W5MIB8 PTHR18884:SF66 SEPTIN SEPTIN-12 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640 cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000000141.1|UniProtKB=W5LVJ8 W5LVJ8 PTHR11977:SF27 VILLIN MACROPHAGE-CAPPING PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;actin filament binding#GO:0051015;actin binding#GO:0003779;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092 cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399;cellular component assembly#GO:0022607;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;central nervous system development#GO:0007417;regulation of actin filament length#GO:0030832;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;multicellular organismal process#GO:0032501;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of actin filament depolymerization#GO:0030834;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;system development#GO:0048731;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;anatomical structure development#GO:0048856 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 FAS signaling pathway#P00020>Gelsolin#P00611 LEPOC|Ensembl=ENSLOCG00000016990.1|UniProtKB=W5NK48 W5NK48 PTHR21646:SF28 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;DNA-templated transcription elongation#GO:0006354;regulation of protein stability#GO:0031647;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000003710.1|UniProtKB=W5M7Q4 W5M7Q4 PTHR11702:SF31 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2 ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000003259.1|UniProtKB=W5M642 W5M642 PTHR12850:SF5 40S RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN ES25 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000003489.1|UniProtKB=W5M6Y0 W5M6Y0 PTHR13866:SF21 SPARC OSTEONECTIN TESTICAN-3 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;calcium ion binding#GO:0005509;peptidase inhibitor activity#GO:0030414;binding#GO:0005488;small molecule binding#GO:0036094;endopeptidase regulator activity#GO:0061135;ion binding#GO:0043167;molecular function inhibitor activity#GO:0140678;cation binding#GO:0043169;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000008866.1|UniProtKB=W5MQY5 W5MQY5 PTHR23408:SF3 METHYLMALONYL-COA MUTASE METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000012953.1|UniProtKB=W5N5P2 W5N5P2 PTHR23330:SF6 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED WASP HOMOLOG-ASSOCIATED PROTEIN WITH ACTIN, MEMBRANES AND MICROTUBULES binding#GO:0005488;protein-containing complex binding#GO:0044877 establishment of localization in cell#GO:0051649;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component organization#GO:0016043;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 LEPOC|Ensembl=ENSLOCG00000012419.1|UniProtKB=W5N3T4 W5N3T4 PTHR46106:SF5 IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE N2 cellular localization#GO:0051641;protein secretion#GO:0009306;regulation of biological quality#GO:0065008;protein transport#GO:0015031;hormone secretion#GO:0046879;response to carbohydrate#GO:0009743;secretion by cell#GO:0032940;intracellular glucose homeostasis#GO:0001678;cellular response to chemical stimulus#GO:0070887;response to monosaccharide#GO:0034284;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;export from cell#GO:0140352;signaling#GO:0023052;response to hexose#GO:0009746;carbohydrate homeostasis#GO:0033500;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of localization#GO:0032879;glucose homeostasis#GO:0042593;cellular response to glucose stimulus#GO:0071333;hormone transport#GO:0009914;chemical homeostasis#GO:0048878;response to chemical#GO:0042221;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular response to oxygen-containing compound#GO:1901701;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;regulation of secretion#GO:0051046;peptide hormone secretion#GO:0030072;signal release#GO:0023061;peptide secretion#GO:0002790;homeostatic process#GO:0042592;cellular response to stimulus#GO:0051716;protein localization to extracellular region#GO:0071692;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;response to glucose#GO:0009749;insulin secretion#GO:0030073;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;peptide transport#GO:0015833 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cell junction#GO:0030054;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;synapse#GO:0045202;organelle#GO:0043226 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000000604.1|UniProtKB=W5LX06 W5LX06 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007158.1|UniProtKB=W5MJV2 W5MJV2 PTHR11639:SF147 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-P calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 endothelial cell migration#GO:0043542;cell migration#GO:0016477;cell motility#GO:0048870;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000004173.1|UniProtKB=W5M9C5 W5M9C5 PTHR11576:SF13 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZP DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011164.1|UniProtKB=W5MZB1 W5MZB1 PTHR13793:SF150 PHD FINGER PROTEINS PHD FINGER PROTEIN 14 chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000008238.1|UniProtKB=W5MNQ4 W5MNQ4 PTHR11905:SF262 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 9 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017822.1|UniProtKB=W5NMR6 W5NMR6 PTHR24247:SF131 5-HYDROXYTRYPTAMINE RECEPTOR ODORANT RECEPTOR-RELATED ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;cation binding#GO:0043169;serotonin binding#GO:0051378;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;heterocyclic compound binding#GO:1901363;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010639.1|UniProtKB=W5MXB8 W5MXB8 PTHR15012:SF37 APICAL PROTEIN/SHROOM-RELATED SHROOM FAMILY MEMBER 1 actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 membraneless organelle#GO:0043228;cell junction#GO:0030054;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical junction complex#GO:0043296;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;cell cortex#GO:0005938 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000014897.1|UniProtKB=W5NCI7 W5NCI7 PTHR12867:SF6 GLYCOSYL TRANSFERASE-RELATED UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG13 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004859.1|UniProtKB=W5MBS9 W5MBS9 PTHR14215:SF1 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 1 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;organelle fission#GO:0048285;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000011332.1|UniProtKB=W5MZW4 W5MZW4 PTHR19143:SF444 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-3 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000011608.1|UniProtKB=W5N0V9 W5N0V9 PTHR22792:SF159 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 7 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015720.1|UniProtKB=W5NFE3 W5NFE3 PTHR43721:SF3 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 2 translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000001183.1|UniProtKB=W5LYY6 W5LYY6 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;regulation of biological process#GO:0050789;cell communication#GO:0007154;immune system process#GO:0002376 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006616.1|UniProtKB=W5MHZ7 W5MHZ7 PTHR12308:SF23 ANOCTAMIN ANOCTAMIN-5 phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000002929.1|UniProtKB=W5M4Z0 W5M4Z0 PTHR15073:SF2 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 1 organelle organization#GO:0006996;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule-based process#GO:0032886;microtubule bundle formation#GO:0001578;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000009053.1|UniProtKB=W5MRS1 W5MRS1 MYH11 PTHR45615:SF23 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-11 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 LEPOC|Ensembl=ENSLOCG00000010150.1|UniProtKB=W5MVL6 W5MVL6 PTHR24412:SF494 KELCH PROTEIN KELCH-LIKE PROTEIN 12 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;protein metabolic process#GO:0019538;COPII-coated vesicle budding#GO:0090114;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;vesicle budding from membrane#GO:0006900;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;membrane organization#GO:0061024;cellular localization#GO:0051641;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;COPII-coated ER to Golgi transport vesicle#GO:0030134;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003060.1|UniProtKB=W5M5D5 W5M5D5 PTHR14519:SF5 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1-LIKE PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;vitamin K metabolic process#GO:0042373;ketone metabolic process#GO:0042180;cellular process#GO:0009987 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013646.1|UniProtKB=W5N866 W5N866 PTHR13093:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1 ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877 ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Swr1 complex#GO:0000812;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014005.1|UniProtKB=W5N9F8 W5N9F8 PTHR11907:SF0 AMIDOPHOSPHORIBOSYLTRANSFERASE AMIDOPHOSPHORIBOSYLTRANSFERASE pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 metabolite interconversion enzyme#PC00262;transferase#PC00220 De novo purine biosynthesis#P02738>Amidophosphoribosyl transferase#P02905 LEPOC|Ensembl=ENSLOCG00000010098.1|UniProtKB=W5MVF0 W5MVF0 PTHR24291:SF119 CYTOCHROME P450 FAMILY 4 SI:CH211-113J14.1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;vitamin D metabolic process#GO:0042359;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000002456.1|UniProtKB=W5M3D1 W5M3D1 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008816.1|UniProtKB=W5MQS2 W5MQS2 PTHR43078:SF54 UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED UDP-GLUCURONIC ACID DECARBOXYLASE 1 catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 decarboxylase#PC00089;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000005005.1|UniProtKB=W5MCC1 W5MCC1 PTHR11686:SF56 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 1 PROENZYME-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;sulfur compound catabolic process#GO:0044273;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;glutathione metabolic process#GO:0006749;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;peptide metabolic process#GO:0006518;modified amino acid metabolic process#GO:0006575;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009267.1|UniProtKB=W5MSE2 W5MSE2 PTHR12740:SF4 JNK1/MAPK8-ASSOCIATED MEMBRANE PROTEIN JNK1_MAPK8-ASSOCIATED MEMBRANE PROTEIN protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002754.1|UniProtKB=W5M4D0 W5M4D0 PTHR33768:SF7 MIP11318P CFAP97 DOMAIN CONTAINING 2 LEPOC|Ensembl=ENSLOCG00000017801.1|UniProtKB=W5NMP6 W5NMP6 PTHR14889:SF3 RCG36411 TLR ADAPTER INTERACTING WITH SLC15A4 ON THE LYSOSOME LEPOC|Ensembl=ENSLOCG00000014300.1|UniProtKB=W5NAE6 W5NAE6 PTHR23101:SF72 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR-LIKE PROTEIN GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;cytosol#GO:0005829;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000015059.1|UniProtKB=W5ND25 W5ND25 PTHR10015:SF274 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 1 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000007435.1|UniProtKB=W5MKW4 W5MKW4 PTHR13266:SF1 PROTEASOME INHIBITOR PROTEASOME INHIBITOR PI31 SUBUNIT regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008108.1|UniProtKB=W5MN88 W5MN88 PTHR26451:SF854 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005063.1|UniProtKB=W5MCI5 W5MCI5 PTHR12644:SF2 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 5-LIKE PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;cell migration#GO:0016477;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Huntington disease#P00029>Arp2/3 complex#P00811 LEPOC|Ensembl=ENSLOCG00000005736.1|UniProtKB=W5MEX2 W5MEX2 PTHR45840:SF6 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 2 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 LEPOC|Ensembl=ENSLOCG00000010782.1|UniProtKB=W5MXV6 W5MXV6 PTHR13723:SF40 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000012483.1|UniProtKB=W5N406 W5N406 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;response to stimulus#GO:0050896 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001113.1|UniProtKB=W5LYP4 W5LYP4 PTHR46440:SF1 HOMEOBOX PROTEIN HOX-D12-RELATED HOMEOBOX PROTEIN HOX-D12 double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002300.1|UniProtKB=W5M2T9 W5M2T9 PTHR12984:SF3 SCY1-RELATED S/T PROTEIN KINASE-LIKE N-TERMINAL KINASE-LIKE PROTEIN non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016885.1|UniProtKB=W5NJR4 W5NJR4 ELOVL5 PTHR11157:SF18 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015366.1|UniProtKB=W5NE66 W5NE66 PTHR24223:SF355 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 5 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000007177.1|UniProtKB=W5MJX6 W5MJX6 PTHR12247:SF89 POLYCOMB GROUP PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 7 histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;protein binding#GO:0005515 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000013310.1|UniProtKB=W5N6Z2 W5N6Z2 PTHR19969:SF15 SH2-SH3 ADAPTOR PROTEIN-RELATED SRC-LIKE-ADAPTER 2 ISOFORM X1 molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971;protein-macromolecule adaptor activity#GO:0030674;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;signaling adaptor activity#GO:0035591 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005961.1|UniProtKB=W5MFN8 W5MFN8 PTHR46987:SF5 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000955.1|UniProtKB=W5LY61 W5LY61 PTHR46674:SF1 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 protein binding#GO:0005515;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;binding#GO:0005488 regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;spermatogenesis#GO:0007283;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;male gamete generation#GO:0048232;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;piRNA processing#GO:0034587;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016337.1|UniProtKB=W5NHS9 W5NHS9 PTHR23043:SF8 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;chemical homeostasis#GO:0048878;animal organ development#GO:0048513;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;blood vessel morphogenesis#GO:0048514;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;myeloid cell differentiation#GO:0030099;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;tissue remodeling#GO:0048771;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;angiogenesis#GO:0001525;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;tube development#GO:0035295;regulation of RNA biosynthetic process#GO:2001141;hemopoiesis#GO:0030097;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;multicellular organismal-level homeostasis#GO:0048871;cellular homeostasis#GO:0019725;response to hypoxia#GO:0001666;intracellular chemical homeostasis#GO:0055082;cellular response to hypoxia#GO:0071456;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;homeostatic process#GO:0042592;homeostasis of number of cells#GO:0048872;erythrocyte differentiation#GO:0030218;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013531.1|UniProtKB=W5N7S8 W5N7S8 PTHR24388:SF34 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 280D DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000005071.1|UniProtKB=W5MCJ8 W5MCJ8 PTHR21166:SF2 CELL DIVISION CONTROL PROTEIN 24 OB DOMAIN-CONTAINING PROTEIN-RELATED MEIOSIS-SPECIFIC WITH OB DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;exonuclease activity#GO:0004527;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788 organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;homologous recombination#GO:0035825;reproductive process#GO:0022414;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA damage response#GO:0006974;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;resolution of meiotic recombination intermediates#GO:0000712;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;response to stimulus#GO:0050896;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001303.1|UniProtKB=W5LZC1 W5LZC1 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002677.1|UniProtKB=W5M446 W5M446 PTHR10157:SF29 DOPAMINE BETA HYDROXYLASE RELATED DOPAMINE BETA-HYDROXYLASE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 amine metabolic process#GO:0009308;phenol-containing compound biosynthetic process#GO:0046189;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to alcohol#GO:0097305;response to chemical#GO:0042221;catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;metabolic process#GO:0008152;response to oxygen-containing compound#GO:1901700;amine catabolic process#GO:0009310;catecholamine metabolic process#GO:0006584 secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141 hydroxylase#PC00122 Dopamine receptor mediated signaling pathway#P05912>DBH#P05955;Adrenaline and noradrenaline biosynthesis#P00001>DBH#P00063 LEPOC|Ensembl=ENSLOCG00000016624.1|UniProtKB=W5NIS8 W5NIS8 PTHR10516:SF455 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYLPROLYL ISOMERASE isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;regulation of heart contraction#GO:0008016;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cell communication#GO:0007154;macromolecule biosynthetic process#GO:0009059;regulation of calcium ion transport#GO:0051924;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269;regulation of system process#GO:0044057;regulation of monoatomic cation transmembrane transport#GO:1904062;calcium-mediated signaling#GO:0019722;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;regulation of muscle system process#GO:0090257;protein folding#GO:0006457;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of muscle contraction#GO:0006937;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of localization#GO:0032879;regulation of transport#GO:0051049 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;sarcoplasmic reticulum#GO:0016529;membrane#GO:0016020;cytoplasm#GO:0005737;sarcoplasmic reticulum membrane#GO:0033017;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 LEPOC|Ensembl=ENSLOCG00000014928.1|UniProtKB=W5NCM6 W5NCM6 PTHR18934:SF278 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX34-RELATED macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011304.1|UniProtKB=W5MZT7 W5MZT7 PTHR18829:SF0 PROTEIN YAE1 HOMOLOG PROTEIN YAE1 HOMOLOG LEPOC|Ensembl=ENSLOCG00000000652.1|UniProtKB=W5LX61 W5LX61 PTHR46708:SF7 TENASCIN FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102;carbohydrate derivative binding#GO:0097367 heart development#GO:0007507;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell-substrate junction organization#GO:0150115;developmental process#GO:0032502;circulatory system development#GO:0072359;cell junction organization#GO:0034330;cell-substrate junction assembly#GO:0007044;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000007937.1|UniProtKB=W5MMN6 W5MMN6 PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A LEPOC|Ensembl=ENSLOCG00000010148.1|UniProtKB=W5MVL7 W5MVL7 PTHR11096:SF1 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN nuclease activity#GO:0004518;ligase activity#GO:0016874;cyclase activity#GO:0009975;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466 small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000629.1|UniProtKB=W5LX39 W5LX39 PTHR11481:SF64 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017504.1|UniProtKB=W5NLV0 W5NLV0 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017139.1|UniProtKB=W5NKM1 W5NKM1 PTHR21472:SF26 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN CONTAINING 1 LEPOC|Ensembl=ENSLOCG00000017270.1|UniProtKB=W5NL53 W5NL53 PEX7 PTHR46027:SF1 PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR signal sequence receptor activity#GO:0005048 peroxisome organization#GO:0007031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;peroxisomal transport#GO:0043574;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000015365.1|UniProtKB=W5NE51 W5NE51 PTHR12114:SF7 PARVIN BETA-PARVIN binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 actin filament-based process#GO:0030029;cell adhesion#GO:0007155;establishment or maintenance of cell polarity#GO:0007163;regulation of biological quality#GO:0065008;cell-substrate adhesion#GO:0031589;regulation of cell shape#GO:0008360;lamellipodium assembly#GO:0030032;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;cell projection organization#GO:0030030;substrate adhesion-dependent cell spreading#GO:0034446;plasma membrane bounded cell projection assembly#GO:0120031;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;cell-substrate junction#GO:0030055;cell projection#GO:0042995;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;lamellipodium#GO:0030027;cell leading edge#GO:0031252 actin or actin-binding cytoskeletal protein#PC00041;actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Parvin#P00945 LEPOC|Ensembl=ENSLOCG00000004685.1|UniProtKB=W5MB55 W5MB55 PTHR46016:SF3 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF114 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 LEPOC|Ensembl=ENSLOCG00000007844.1|UniProtKB=W5MMB9 W5MMB9 PTHR47135:SF3 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7-LIKE LEPOC|Ensembl=ENSLOCG00000010351.1|UniProtKB=W5MWC7 W5MWC7 PTHR11839:SF15 UDP/ADP-SUGAR PYROPHOSPHATASE URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT14 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 pyrophosphatase#PC00196;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015702.1|UniProtKB=W5NFC5 W5NFC5 PTHR23152:SF38 2-OXOGLUTARATE DEHYDROGENASE 2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1 catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987 oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012126.1|UniProtKB=W5N2R8 W5N2R8 PTHR42737:SF2 GLUTATHIONE REDUCTASE GLUTATHIONE REDUCTASE, MITOCHONDRIAL antioxidant activity#GO:0016209;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;disulfide oxidoreductase activity#GO:0015036;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660 cellular response to stimulus#GO:0051716;modified amino acid metabolic process#GO:0006575;homeostatic process#GO:0042592;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;glutathione metabolic process#GO:0006749;cellular process#GO:0009987;response to stress#GO:0006950;sulfur compound metabolic process#GO:0006790;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;metabolic process#GO:0008152;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000006855.1|UniProtKB=W5MIT4 W5MIT4 PTHR12072:SF5 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 2 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000007713.1|UniProtKB=W5MLV6 W5MLV6 PTHR16206:SF11 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 1B positive regulation of signaling#GO:0023056;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of signal transduction#GO:0009967;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012116.1|UniProtKB=W5N2P9 W5N2P9 PTHR12306:SF8 CELL DEATH ACTIVATOR CIDE LIPID TRANSFERASE CIDEA lipid transfer activity#GO:0120013;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 lipid storage#GO:0019915;cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915;organelle organization#GO:0006996;cellular component organization#GO:0016043;programmed cell death#GO:0012501;organelle fusion#GO:0048284;lipid droplet organization#GO:0034389;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006552.1|UniProtKB=W5MHQ8 W5MHQ8 PTHR45638:SF2 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ALPHA-4 gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;monoatomic cation transmembrane transporter activity#GO:0008324;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;monoatomic ion channel activity#GO:0005216;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;channel activity#GO:0015267;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261 sensory perception of chemical stimulus#GO:0007606;transport#GO:0006810;nervous system process#GO:0050877;sensory perception#GO:0007600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;system process#GO:0003008;cellular process#GO:0009987;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 ion channel#PC00133;ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000002881.1|UniProtKB=W5M4T5 W5M4T5 PTHR11955:SF90 FATTY ACID BINDING PROTEIN FATTY ACID BINDING PROTEIN 11A fatty acid binding#GO:0005504;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;organic acid binding#GO:0043177 organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;fatty acid transport#GO:0015908;localization#GO:0051179;macromolecule localization#GO:0033036;lipid transport#GO:0006869 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000005385.1|UniProtKB=W5MDN2 W5MDN2 PTHR19957:SF139 SYNTAXIN SYNTAXIN-17 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;macromolecule localization#GO:0033036 vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;autophagosome#GO:0005776;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;membrane protein complex#GO:0098796;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000017883.1|UniProtKB=W5NMX7 W5NMX7 PTHR31815:SF0 AGAP005329-PA TRANSMEMBRANE PROTEIN 200A LEPOC|Ensembl=ENSLOCG00000011138.1|UniProtKB=W5MZ71 W5MZ71 PTHR11364:SF27 THIOSULFATE SULFERTANSFERASE SULFURTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble position uridine thiolation#GO:0002143;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA thio-modification#GO:0034227;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000017674.1|UniProtKB=W5NMC0 W5NMC0 PTHR45822:SF8 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 3 ISOFORM X2-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;biological regulation#GO:0065007;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to fatty acid#GO:0071398;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to fatty acid#GO:0070542;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000012842.1|UniProtKB=W5N595 W5N595 PTHR10965:SF0 60S RIBOSOMAL PROTEIN L38 LARGE RIBOSOMAL SUBUNIT PROTEIN EL38 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000001932.1|UniProtKB=W5M1H7 W5M1H7 PTHR45476:SF7 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL 3 monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509 transport#GO:0006810;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000005412.1|UniProtKB=W5MDR8 W5MDR8 PTHR10405:SF29 SPINDLIN SPINDLIN-W histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone H3 reader activity#GO:0140006;chromatin-protein adaptor activity#GO:0140463 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014481.1|UniProtKB=W5NB14 W5NB14 PTHR14571:SF8 HISTONE-LYSINE N-METHYLTRANSFERASE SET-26-RELATED PHD FINGER PROTEIN 23 regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of protein ubiquitination#GO:0031396;regulation of autophagosome maturation#GO:1901096;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of protein modification process#GO:0031399;negative regulation of autophagy#GO:0010507;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of catabolic process#GO:0009895;negative regulation of protein-containing complex disassembly#GO:0043242;positive regulation of biological process#GO:0048518;negative regulation of macroautophagy#GO:0016242;regulation of protein metabolic process#GO:0051246;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macroautophagy#GO:0016241;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;positive regulation of protein metabolic process#GO:0051247;regulation of autophagosome assembly#GO:2000785;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013371.1|UniProtKB=W5N774 W5N774 PTHR18884:SF47 SEPTIN SEPTIN-9 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402 cell periphery#GO:0071944;cell cortex#GO:0005938;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000014272.1|UniProtKB=W5NAB7 W5NAB7 PTHR10677:SF25 UBIQUILIN UBIQUITIN-LIKE PROTEIN 7 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007473.1|UniProtKB=W5ML26 W5ML26 PTHR13771:SF9 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 1 ISOFORM X1-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016636.1|UniProtKB=W5NIU2 W5NIU2 PTHR28469:SF1 ECTODYSPLASIN-A RECEPTOR-ASSOCIATED ADAPTER PROTEIN ECTODYSPLASIN-A RECEPTOR-ASSOCIATED ADAPTER PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001288.1|UniProtKB=W5LZB8 W5LZB8 PTHR24346:SF38 MAP/MICROTUBULE AFFINITY-REGULATING KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016294.1|UniProtKB=W5NHK2 W5NHK2 FBXO11 PTHR22990:SF20 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 11 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010282.1|UniProtKB=W5MW28 W5MW28 PTHR16502:SF0 KERATINOCYTE-ASSOCIATED TRANSMEMBRANE PROTEIN 2 KERATINOCYTE-ASSOCIATED TRANSMEMBRANE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000006836.1|UniProtKB=W5MIR2 W5MIR2 PTHR13036:SF0 BETA1,4 MANNOSYLTRANSFERASE CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000003688.1|UniProtKB=W5M7M5 W5M7M5 PTHR15654:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 263 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043 cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000012357.1|UniProtKB=W5N3L1 W5N3L1 PTHR14791:SF22 BOMB/KIRA PROTEINS PROTEIN KIBRA protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899 regulation of growth#GO:0040008;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of macromolecule metabolic process#GO:0060255;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of multicellular organismal process#GO:0051239;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cell migration#GO:0016477;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of response to stimulus#GO:0048583;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004899.1|UniProtKB=W5MBX4 W5MBX4 PTHR24300:SF319 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;binding#GO:0005488;tetrapyrrole binding#GO:0046906 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002718.1|UniProtKB=W5M496 W5M496 PTHR11037:SF13 TRANSCRIPTION FACTOR CP2 UPSTREAM-BINDING PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010610.1|UniProtKB=W5MX90 W5MX90 PTHR10528:SF15 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER 4 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;system process#GO:0003008;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;DNA-templated transcription elongation#GO:0006354;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;gene expression#GO:0010467;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;nervous system process#GO:0050877;regulation of DNA-templated transcription#GO:0006355;RNA metabolic process#GO:0016070;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011650.1|UniProtKB=W5N107 W5N107 PTHR15396:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P40 RIBONUCLEASE P PROTEIN SUBUNIT P40 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;ribonuclease P activity#GO:0004526;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;nuclease activity#GO:0004518 cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;tRNA processing#GO:0008033;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 catalytic complex#GO:1902494;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;ribonucleoprotein complex#GO:1990904;intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;protein-containing complex#GO:0032991;multimeric ribonuclease P complex#GO:0030681;ribonuclease MRP complex#GO:0000172 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011642.1|UniProtKB=W5N0Z3 W5N0Z3 PTHR45921:SF2 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000003156.1|UniProtKB=W5M5R8 W5M5R8 PTHR46542:SF1 X-BOX BINDING PROTEIN 1 X-BOX-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000017624.1|UniProtKB=W5NM70 W5NM70 PTHR24173:SF12 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941 intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012925.1|UniProtKB=W5N5K3 W5N5K3 PTHR31872:SF5 TRANSMEMBRANE PROTEIN 179 TRANSMEMBRANE PROTEIN 179 LEPOC|Ensembl=ENSLOCG00000003284.1|UniProtKB=W5M694 W5M694 PTHR48015:SF14 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE TAO3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005962.1|UniProtKB=W5MFP2 W5MFP2 PTHR10782:SF9 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS4 catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678;acyltransferase activity#GO:0016746;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787 negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;protein sumoylation#GO:0016925;metabolic process#GO:0008152;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;negative regulation of cell communication#GO:0010648;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958;JAK/STAT signaling pathway#P00038>PIAS#P01031 LEPOC|Ensembl=ENSLOCG00000012351.1|UniProtKB=W5N3J3 W5N3J3 PTHR13628:SF1 TRANSMEMBRANE PROTEIN 267 TRANSMEMBRANE PROTEIN 267 LEPOC|Ensembl=ENSLOCG00000001238.1|UniProtKB=W5LZ50 W5LZ50 PTHR12353:SF19 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 4 modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051 postsynapse#GO:0098794;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic specialization#GO:0099572;cell junction#GO:0030054;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011139.1|UniProtKB=W5MZ73 W5MZ73 PTHR45896:SF1 N-ALPHA-ACETYLTRANSFERASE 30 N-ALPHA-ACETYLTRANSFERASE 30 protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;acetyltransferase complex#GO:1902493 metabolite interconversion enzyme#PC00262;transferase#PC00220;acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000017827.1|UniProtKB=W5NMS1 W5NMS1 PTHR23401:SF3 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 2 kinase activator activity#GO:0019209;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;nervous system development#GO:0007399;head development#GO:0060322;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;brain development#GO:0007420;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;anatomical structure development#GO:0048856;system development#GO:0048731 neuron projection#GO:0043005;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cellular anatomical structure#GO:0110165;axon#GO:0030424;growth cone#GO:0030426;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000014747.1|UniProtKB=W5NBZ8 W5NBZ8 PTHR31792:SF3 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000005910.1|UniProtKB=W5MFH6 W5MFH6 PTHR10071:SF289 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 heart development#GO:0007507;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;striated muscle tissue development#GO:0014706;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell fate commitment#GO:0045165;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;tissue development#GO:0009888;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000018354.1|UniProtKB=W5NP96 W5NP96 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008650.1|UniProtKB=W5MQ58 W5MQ58 PTHR45691:SF18 PROTEIN DIAPHANOUS FH2 DOMAIN-CONTAINING PROTEIN 1 actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012916.1|UniProtKB=W5N5J5 W5N5J5 PTHR11571:SF224 GLUTATHIONE S-TRANSFERASE HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000006787.1|UniProtKB=W5MIJ2 W5MIJ2 PTHR46152:SF1 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000008787.1|UniProtKB=W5MQN7 W5MQN7 PTHR45624:SF22 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL ORNITHINE TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215 carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865;intracellular transport#GO:0046907;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;amino acid transmembrane transport#GO:0003333;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013801.1|UniProtKB=W5N8R1 W5N8R1 PTHR44019:SF2 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG A organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000015171.1|UniProtKB=W5NDG1 W5NDG1 PTHR10416:SF0 DNA POLYMERASE DELTA SUBUNIT 2 DNA POLYMERASE DELTA SUBUNIT 2 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;DNA synthesis involved in DNA replication#GO:0090592;DNA-templated DNA replication#GO:0006261;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-DNA complex#GO:0032993;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;replisome#GO:0030894;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 DNA replication#P00017>Pol delta#P00533 LEPOC|Ensembl=ENSLOCG00000013866.1|UniProtKB=W5N8Z9 W5N8Z9 PTHR22762:SF92 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;alpha-glucosidase activity#GO:0090599 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;generation of precursor metabolites and energy#GO:0006091;lytic vacuole organization#GO:0080171;organelle organization#GO:0006996;glycogen catabolic process#GO:0005980;cellular process#GO:0009987;lysosome organization#GO:0007040;carbohydrate catabolic process#GO:0016052;vacuole organization#GO:0007033;energy reserve metabolic process#GO:0006112;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;glycogen metabolic process#GO:0005977;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;polysaccharide catabolic process#GO:0000272 glucosidase#PC00108 LEPOC|Ensembl=ENSLOCG00000001795.1|UniProtKB=W5M124 W5M124 PTHR15367:SF6 DNA-DIRECTED RNA POLYMERASE III RNA POLYMERASE III SUBUNIT G nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227 DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000011136.1|UniProtKB=W5MZ62 W5MZ62 PTHR31454:SF2 ACTIVE REGULATOR OF SIRT1 ACTIVE REGULATOR OF SIRT1 protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000003561.1|UniProtKB=W5M763 W5M763 PTHR12746:SF2 NONSENSE-MEDIATED MRNA DECAY PROTEIN 3 60S RIBOSOMAL EXPORT PROTEIN NMD3 binding#GO:0005488;ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022 intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle localization#GO:0051640;ribosome biogenesis#GO:0042254;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;ribosomal large subunit export from nucleus#GO:0000055;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000006830.1|UniProtKB=W5MIT0 W5MIT0 PTHR24025:SF0 DESMOGLEIN FAMILY MEMBER DESMOCOLLIN-2 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000016498.1|UniProtKB=W5NIC1 W5NIC1 PTHR46921:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 regulation of developmental process#GO:0050793;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of T cell proliferation#GO:0042129;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cell death#GO:0008219;negative regulation of multicellular organismal process#GO:0051241;programmed cell death#GO:0012501;regulation of cell population proliferation#GO:0042127;regulation of nervous system development#GO:0051960;negative regulation of T cell activation#GO:0050868;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;adaptive immune response#GO:0002250;negative regulation of cell adhesion#GO:0007162;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;immune response#GO:0006955;negative regulation of cell population proliferation#GO:0008285;negative regulation of cell activation#GO:0050866;regulation of system process#GO:0044057;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;regulation of cell activation#GO:0050865;regulation of multicellular organismal development#GO:2000026;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;neuron apoptotic process#GO:0051402;immune system process#GO:0002376;negative regulation of leukocyte activation#GO:0002695;regulation of multicellular organismal process#GO:0051239;negative regulation of lymphocyte activation#GO:0051250;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;cellular process#GO:0009987;regulation of mononuclear cell proliferation#GO:0032944;regulation of B cell activation#GO:0050864;negative regulation of T cell proliferation#GO:0042130;regulation of leukocyte proliferation#GO:0070663;regulation of B cell proliferation#GO:0030888;humoral immune response#GO:0006959 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008562.1|UniProtKB=W5MPV3 W5MPV3 PTHR13077:SF7 SELENOPROTEIN F SELENOPROTEIN M oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000000382.1|UniProtKB=W5LWA9 W5LWA9 PTHR11440:SF18 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED PHOSPHATIDYLCHOLINE-STEROL ACYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000011593.1|UniProtKB=W5N0T7 W5N0T7 PTHR44566:SF1 TRANSDUCIN/WD40 REPEAT-LIKE SUPERFAMILY PROTEIN WD REPEAT-CONTAINING PROTEIN 25 LEPOC|Ensembl=ENSLOCG00000017953.1|UniProtKB=W5NN47 W5NN47 PTHR16840:SF8 GROWTH ARREST-SPECIFIC PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 1 regulation of cellular process#GO:0050794;regulation of transport#GO:0051049;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000015744.1|UniProtKB=W5NFH0 W5NFH0 PTHR11021:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F SMALL NUCLEAR RIBONUCLEOPROTEIN F RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000009836.1|UniProtKB=W5MUG1 W5MUG1 PTHR11449:SF1 RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN EL30 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012771.1|UniProtKB=W5N506 W5N506 PTHR20516:SF1 TRANSMEMBRANE PROTEIN 114/235 FAMILY MEMBER TRANSMEMBRANE PROTEIN 235 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000011577.1|UniProtKB=W5N0R7 W5N0R7 PTHR22848:SF0 WD40 REPEAT PROTEIN WD40 REPEAT-CONTAINING PROTEIN SMU1 RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000002016.1|UniProtKB=W5M1T0 W5M1T0 PTHR11767:SF44 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 11 potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843 inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000011559.1|UniProtKB=W5N0P6 W5N0P6 PTHR11977:SF87 VILLIN SUPERVILLIN ISOFORM X1 phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092 regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000018190.1|UniProtKB=W5NNT2 W5NNT2 PTHR19372:SF7 SULFITE REDUCTASE SULFITE OXIDASE, MITOCHONDRIAL mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 reductase#PC00198;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015491.1|UniProtKB=W5NEK9 W5NEK9 PTHR13520:SF0 RAD50-INTERACTING PROTEIN 1 RINT-1 RAD50-INTERACTING PROTEIN 1 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004850.1|UniProtKB=W5MBS4 W5MBS4 PTHR16521:SF3 TYPE-1 ANGIOTENSIN II RECEPTOR-ASSOCIATED PROTEIN TYPE-1 ANGIOTENSIN II RECEPTOR-ASSOCIATED PROTEIN regulation of biological quality#GO:0065008;system process#GO:0003008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;circulatory system process#GO:0003013;regulation of blood pressure#GO:0008217 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006064.1|UniProtKB=W5MG10 W5MG10 PTHR22168:SF7 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000000889.1|UniProtKB=W5LXY2 W5LXY2 PTHR10265:SF44 CYCLIN-DEPENDENT KINASE INHIBITOR 1 CYCLIN-DEPENDENT KINASE INHIBITOR 1C kinase inhibitor activity#GO:0019210;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell cycle#GO:0045786;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase inhibitor#PC00139;kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000007817.1|UniProtKB=W5MM77 W5MM77 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000479.1|UniProtKB=W5LWL8 W5LWL8 PTHR45134:SF5 OS08G0543275 PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002426.1|UniProtKB=W5M391 W5M391 PTHR11085:SF5 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL transferase activity#GO:0016740;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;acyltransferase activity#GO:0016746;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001462.1|UniProtKB=W5LZX8 W5LZX8 PTHR24270:SF24 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transfer/carrier protein#PC00219;apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000004645.1|UniProtKB=W5MB06 W5MB06 PTHR45887:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON TRANSLATION INITIATION FACTOR EIF2B SUBUNIT EPSILON enzyme regulator activity#GO:0030234;protein binding#GO:0005515;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;molecular function regulator activity#GO:0098772;translation initiation factor activity#GO:0003743;translation initiation factor binding#GO:0031369;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;translation factor activity#GO:0180051 guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000016474.1|UniProtKB=W5NI99 W5NI99 PTHR12287:SF21 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 regulation of cell projection organization#GO:0031344;regulation of response to stimulus#GO:0048583;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;regulation of signaling#GO:0023051;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;regulation of cell projection assembly#GO:0060491;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;response to stimulus#GO:0050896;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of cellular component biogenesis#GO:0044087 cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;cell projection membrane#GO:0031253;ruffle#GO:0001726 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016962.1|UniProtKB=W5NK11 W5NK11 PTHR24205:SF7 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 5 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000008242.1|UniProtKB=W5MNR0 W5MNR0 PTHR16265:SF1 PTB-CONTAINING, CUBILIN AND LRP1-INTERACTING PROTEIN PTB-CONTAINING, CUBILIN AND LRP1-INTERACTING PROTEIN biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of reactive oxygen species metabolic process#GO:2000377;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000015304.1|UniProtKB=W5NDX1 W5NDX1 PTHR12356:SF19 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 3 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006418.1|UniProtKB=W5MH94 W5MH94 PTHR13680:SF41 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON SULFUR DOMAIN 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;binding#GO:0005488;small molecule binding#GO:0036094;transaminase activity#GO:0008483;iron-sulfur cluster binding#GO:0051536 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011783.1|UniProtKB=W5N1I5 W5N1I5 PTHR21040:SF6 BCDNA.GH04120 HEXOSAMINIDASE D hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 LEPOC|Ensembl=ENSLOCG00000011749.1|UniProtKB=W5N1D5 W5N1D5 PTHR10903:SF170 GTPASE, IMAP FAMILY MEMBER-RELATED AIG1-TYPE G DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000004725.1|UniProtKB=W5MBC5 W5MBC5 PTHR16134:SF19 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 18 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014213.1|UniProtKB=W5NA46 W5NA46 PTHR12352:SF13 SECRETED MODULAR CALCIUM-BINDING PROTEIN SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 1 carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;heparin binding#GO:0008201;extracellular matrix binding#GO:0050840 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000016181.1|UniProtKB=W5NH40 W5NH40 PTHR12157:SF18 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 1 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;export from cell#GO:0140352;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;cellular localization#GO:0051641;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;neurotransmitter transport#GO:0006836;cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;regulation of transport#GO:0051049;regulation of localization#GO:0032879;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytic process#GO:0140029;regulated exocytosis#GO:0045055 presynapse#GO:0098793;cell cortex#GO:0005938;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic membrane#GO:0097060;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;presynaptic active zone#GO:0048786 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>RIM1alpha/2alpha#P05776 LEPOC|Ensembl=ENSLOCG00000003378.1|UniProtKB=W5M6J2 W5M6J2 PTHR12053:SF4 PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED CARBOXYPEPTIDASE Q metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;primary metabolic process#GO:0044238;peptide catabolic process#GO:0043171;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001879.1|UniProtKB=W5M1B9 W5M1B9 PTHR13359:SF2 39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML40 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000018362.1|UniProtKB=W5NPA4 W5NPA4 PTHR19290:SF53 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 23 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000009283.1|UniProtKB=W5MSI4 W5MSI4 PTHR19878:SF6 AUTOPHAGY PROTEIN 16-LIKE AUTOPHAGY-RELATED PROTEIN 16-1 protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle assembly#GO:0070925;metabolic process#GO:0008152;vacuole organization#GO:0007033;autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;phagophore assembly site#GO:0000407;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000008536.1|UniProtKB=W5MPS9 W5MPS9 PTHR13056:SF0 VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;guanyl-nucleotide exchange factor complex#GO:0032045;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000008318.1|UniProtKB=W5MNZ7 W5MNZ7 LRAT PTHR46678:SF2 LECITHIN RETINOL ACYLTRANSFERASE LECITHIN RETINOL ACYLTRANSFERASE B, TANDEM DUPLICATE 2 PRECURSOR-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;cellular process#GO:0009987;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;rough endoplasmic reticulum#GO:0005791;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000001376.1|UniProtKB=W5LZL1 W5LZL1 PTHR10252:SF156 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 LEPOC|Ensembl=ENSLOCG00000002320.1|UniProtKB=W5M314 W5M314 PTHR11654:SF603 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 2 oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;dipeptide transport#GO:0042938;oligopeptide transport#GO:0006857;transport#GO:0006810;import across plasma membrane#GO:0098739;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002468.1|UniProtKB=W5M3F6 W5M3F6 PTHR11093:SF2 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 2 nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 protein-containing complex organization#GO:0043933;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular component assembly#GO:0022607;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component biogenesis#GO:0044085;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;protein-RNA complex assembly#GO:0022618;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;Ino80 complex#GO:0031011;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118 LEPOC|Ensembl=ENSLOCG00000003365.1|UniProtKB=W5M6H5 W5M6H5 PTHR48071:SF5 SRCR DOMAIN-CONTAINING PROTEIN NEUROTRYPSIN catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;zymogen activation#GO:0031638;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 axon terminus#GO:0043679;cell junction#GO:0030054;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;neuron projection#GO:0043005;presynapse#GO:0098793;membrane#GO:0016020;extracellular region#GO:0005576;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;neuron projection terminus#GO:0044306;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202 LEPOC|Ensembl=ENSLOCG00000001563.1|UniProtKB=W5M0D3 W5M0D3 PTHR12011:SF41 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR B2 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;developmental process#GO:0032502;multicellular organism development#GO:0007275;peripheral nervous system development#GO:0007422;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 p53 pathway#P00059>BAI-1#G04699 LEPOC|Ensembl=ENSLOCG00000003196.1|UniProtKB=W5M5W8 W5M5W8 PTHR45640:SF7 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-1 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to heat#GO:0009408;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;protein folding#GO:0006457 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 p38 MAPK pathway#P05918>HSP27#P06016;VEGF signaling pathway#P00056>HSP27#P01412;CCKR signaling map#P06959>HSP27#P07154;Angiogenesis#P00005>HSP27#P00231 LEPOC|Ensembl=ENSLOCG00000000998.1|UniProtKB=W5LYC2 W5LYC2 PTHR11999:SF167 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE AROMATIC-L-AMINO-ACID DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 metabolic process#GO:0008152;serotonin metabolic process#GO:0042428;catecholamine metabolic process#GO:0006584;phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;phenol-containing compound biosynthetic process#GO:0046189;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;serotonin biosynthetic process#GO:0042427 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lyase#PC00144;decarboxylase#PC00089 Nicotine pharmacodynamics pathway#P06587>DDC#P06608;Dopamine receptor mediated signaling pathway#P05912>DOPA decarb.#P05961;Adrenaline and noradrenaline biosynthesis#P00001>DOPA decarb.#P00066;5-Hydroxytryptamine biosynthesis#P04371>Aromatic L-amino acid decarboxylase#P04400 LEPOC|Ensembl=ENSLOCG00000017783.1|UniProtKB=W5NMM8 W5NMM8 PTHR10270:SF313 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-21 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000005300.1|UniProtKB=W5MDC7 W5MDC7 PTHR12461:SF104 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 5 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;RNA binding#GO:0003723;tRNA binding#GO:0000049;catalytic activity, acting on a tRNA#GO:0140101;nucleic acid binding#GO:0003676;binding#GO:0005488 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003445.1|UniProtKB=W5M6S6 W5M6S6 PTHR15427:SF27 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 5 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;protein secretion#GO:0009306;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;transport#GO:0006810;export from cell#GO:0140352;establishment of protein localization#GO:0045184;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;macromolecule localization#GO:0033036 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016121.1|UniProtKB=W5NGW2 W5NGW2 PTHR12301:SF13 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM AND SH3 DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1-RELATED positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 LEPOC|Ensembl=ENSLOCG00000005486.1|UniProtKB=W5ME11 W5ME11 PTHR15169:SF0 DAMAGE-SPECIFIC DNA BINDING PROTEIN 2 DNA DAMAGE-BINDING PROTEIN 2 DNA binding#GO:0003677;damaged DNA binding#GO:0003684;binding#GO:0005488;nucleic acid binding#GO:0003676 response to stress#GO:0006950;response to radiation#GO:0009314;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;response to UV#GO:0009411;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 damaged DNA-binding protein#PC00086 p53 pathway#P00059>p48#G04705 LEPOC|Ensembl=ENSLOCG00000002004.1|UniProtKB=W5M1Q9 W5M1Q9 PTHR45652:SF4 GLIAL FIBRILLARY ACIDIC PROTEIN SI:DKEY-33C12.3 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918;structural constituent of cytoskeleton#GO:0005200 intermediate filament organization#GO:0045109;intermediate filament bundle assembly#GO:0045110;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;intermediate filament cytoskeleton organization#GO:0045104 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;axon#GO:0030424;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;intermediate filament#GO:0005882;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;neuron projection#GO:0043005 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000014327.1|UniProtKB=W5NAI7 W5NAI7 PTHR11822:SF46 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;NADP+ metabolic process#GO:0006739;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nicotinamide nucleotide metabolic process#GO:0046496;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013706.1|UniProtKB=W5N8E7 W5N8E7 PTHR13865:SF25 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN 1 protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 localization#GO:0051179;anatomical structure development#GO:0048856;tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;protein localization to cell junction#GO:1902414;animal gross anatomical part developmental process#GO:0160108;circulatory system process#GO:0003013;cell adhesion#GO:0007155;cell differentiation#GO:0030154;cell junction organization#GO:0034330;homeostatic process#GO:0042592;cell development#GO:0048468;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;intracellular protein localization#GO:0008104;system process#GO:0003008;multicellular organismal-level homeostasis#GO:0048871;developmental process#GO:0032502;endothelial cell differentiation#GO:0045446;cell-cell junction organization#GO:0045216;epithelium development#GO:0060429;blood circulation#GO:0008015;tissue development#GO:0009888;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;epithelial cell differentiation#GO:0030855;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cell-cell adhesion#GO:0098609;cellular process#GO:0009987 apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000011096.1|UniProtKB=W5MZ19 W5MZ19 PTHR24241:SF133 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OXYTOCIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 response to hormone#GO:0009725;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of system process#GO:0044057;regulation of anatomical structure size#GO:0090066;system process#GO:0003008;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;cell communication#GO:0007154;regulation of biological quality#GO:0065008 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005419.1|UniProtKB=W5MDS8 W5MDS8 PTHR11818:SF7 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A2 structural molecule activity#GO:0005198 sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013212.1|UniProtKB=W5N6L4 W5N6L4 PTHR43798:SF5 MONOACYLGLYCEROL LIPASE MONOACYLGLYCEROL LIPASE ABHD6 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016284.1|UniProtKB=W5NHI3 W5NHI3 PTHR12694:SF9 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TFIIA-ALPHA AND BETA-LIKE FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription coregulator activity#GO:0003712;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390;General transcription regulation#P00023>TFIIA complex#P00662 LEPOC|Ensembl=ENSLOCG00000017724.1|UniProtKB=W5NMG9 W5NMG9 PTHR46617:SF5 FORKHEAD BOX PROTEIN G1 FORKHEAD BOX PROTEIN G1 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000016190.1|UniProtKB=W5NH47 W5NH47 PTHR23204:SF10 CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000002138.1|UniProtKB=W5M276 W5M276 PTHR22750:SF59 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;bioactive lipid receptor activity#GO:0045125;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017428.1|UniProtKB=W5NLM4 W5NLM4 PTHR12002:SF203 CLAUDIN CLAUDIN-RELATED cellular process#GO:0009987;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;transport#GO:0006810;cell-cell junction assembly#GO:0007043;paracellular transport#GO:0160184;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;apical junction complex#GO:0043296 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000008817.1|UniProtKB=W5MQT6 W5MQT6 PTHR23192:SF71 OLFACTOMEDIN-RELATED ADHESION G PROTEIN-COUPLED RECEPTOR L1 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006696.1|UniProtKB=W5MI80 W5MI80 PTHR19300:SF64 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011838.1|UniProtKB=W5N1Q9 W5N1Q9 PTHR24056:SF52 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 18 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009171.1|UniProtKB=W5MS26 W5MS26 PTHR43677:SF4 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROTEIN CRYZL2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 LEPOC|Ensembl=ENSLOCG00000016311.1|UniProtKB=W5NHM4 W5NHM4 PTHR13802:SF69 MUCIN 4-RELATED DENDRITE EXTENSION DEFECTIVE PROTEIN 1-LIKE-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000017137.1|UniProtKB=W5NKM0 W5NKM0 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010080.1|UniProtKB=W5MVB7 W5MVB7 PTHR10390:SF12 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX6 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;visual system development#GO:0150063;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;sensory system development#GO:0048880;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006047.1|UniProtKB=W5MG04 W5MG04 PTHR24356:SF230 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000010718.1|UniProtKB=W5MXM5 W5MXM5 PTHR18945:SF916 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-2 monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;chloride channel activity#GO:0005254;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089 trans-synaptic signaling#GO:0099537;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synapse#GO:0045202;plasma membrane#GO:0005886;GABA-ergic synapse#GO:0098982;signaling receptor complex#GO:0043235;cell junction#GO:0030054 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000004118.1|UniProtKB=W5M965 W5M965 PTHR24088:SF0 28S RIBOSOMAL PROTEIN S17, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US17M mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000002676.1|UniProtKB=W5M431 W5M431 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009799.1|UniProtKB=W5MUC0 W5MUC0 PTHR23322:SF6 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 7 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016668.1|UniProtKB=W5NIY3 W5NIY3 PTHR19432:SF35 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000005809.1|UniProtKB=W5MF61 W5MF61 PTHR21451:SF0 HISTONE H3 METHYLTRANSFERASE HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;negative regulation of macromolecule metabolic process#GO:0010605;DNA integrity checkpoint signaling#GO:0031570;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of cell cycle phase transition#GO:1901988;cellular response to stress#GO:0033554;regulation of cell cycle process#GO:0010564;heterochromatin organization#GO:0070828;cell cycle checkpoint signaling#GO:0000075;cellular component assembly#GO:0022607;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;constitutive heterochromatin formation#GO:0140719;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008722.1|UniProtKB=W5MQG1 W5MQG1 PTHR21569:SF47 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9M binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000000944.1|UniProtKB=W5LY46 W5LY46 PTHR47008:SF1 PROTEIN CORDON-BLEU PROTEIN CORDON-BLEU protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin monomer binding#GO:0003785;binding#GO:0005488 protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;cell body#GO:0044297;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;axonal growth cone#GO:0044295;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;cell leading edge#GO:0031252;neuron projection#GO:0043005;actin filament#GO:0005884;neuronal cell body#GO:0043025;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;growth cone#GO:0030426;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;ruffle#GO:0001726;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000011506.1|UniProtKB=W5N0H8 W5N0H8 PTHR24028:SF247 CADHERIN-87A PROTOCADHERIN-1 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000009595.1|UniProtKB=W5MTL9 W5MTL9 PTHR11024:SF3 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER NUCLEOPORIN SEH1 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to amino acid starvation#GO:0034198;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to nutrient levels#GO:0031667;response to stress#GO:0006950;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;Seh1-associated complex#GO:0035859;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nuclear pore outer ring#GO:0031080;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006908.1|UniProtKB=W5MIZ6 W5MIZ6 PTHR11394:SF178 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005405.1|UniProtKB=W5MDQ9 W5MDQ9 PTHR11849:SF307 ETS FEV TRANSCRIPTION FACTOR, ETS FAMILY MEMBER DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000003463.1|UniProtKB=W5M6V2 W5M6V2 PTHR14453:SF89 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14 glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transcription regulator activity#GO:0140110;pentosyltransferase activity#GO:0016763 regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;negative regulation of response to cytokine stimulus#GO:0060761;regulation of immune system process#GO:0002682;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of defense response#GO:0031347;negative regulation of immune response#GO:0050777;regulation of immune response#GO:0050776;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of response to cytokine stimulus#GO:0060759;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968;negative regulation of innate immune response#GO:0045824;negative regulation of response to external stimulus#GO:0032102;regulation of response to external stimulus#GO:0032101;negative regulation of cytokine-mediated signaling pathway#GO:0001960;regulation of cytokine-mediated signaling pathway#GO:0001959 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000008611.1|UniProtKB=W5MQ21 W5MQ21 PTHR23359:SF105 NUCLEOTIDE KINASE ADENYLATE KINASE 7 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000008058.1|UniProtKB=W5MN26 W5MN26 PTHR12903:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN UL24M macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000000681.1|UniProtKB=W5LX96 W5LX96 PTHR46790:SF1 CENTROMERE PROTEIN N CENTROMERE PROTEIN N intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000006713.1|UniProtKB=W5MI99 W5MI99 PTHR23019:SF1 NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210-LIKE nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000082.1|UniProtKB=W5LVD6 W5LVD6 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000003479.1|UniProtKB=W5M719 W5M719 PTHR11733:SF130 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED ENDOTHELIN-CONVERTING ENZYME 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;gene expression#GO:0010467;protein maturation#GO:0051604;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;proteolysis#GO:0006508;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 LEPOC|Ensembl=ENSLOCG00000005890.1|UniProtKB=W5MFF5 W5MFF5 PTHR15107:SF5 RETINOBLASTOMA BINDING PROTEIN 8 RBBP8 N-TERMINAL-LIKE PROTEIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;damaged DNA binding#GO:0003684 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via single-strand annealing#GO:0045002;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;double-strand break repair#GO:0006302 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000010637.1|UniProtKB=W5MXD0 W5MXD0 PTHR46106:SF1 IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE-LIKE N response to monosaccharide#GO:0034284;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;protein secretion#GO:0009306;cellular localization#GO:0051641;secretion by cell#GO:0032940;response to carbohydrate#GO:0009743;intracellular glucose homeostasis#GO:0001678;protein transport#GO:0015031;regulation of biological quality#GO:0065008;hormone secretion#GO:0046879;response to hexose#GO:0009746;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;carbohydrate homeostasis#GO:0033500;response to stimulus#GO:0050896;signaling#GO:0023052;export from cell#GO:0140352;cellular response to glucose stimulus#GO:0071333;chemical homeostasis#GO:0048878;hormone transport#GO:0009914;regulation of localization#GO:0032879;regulation of transport#GO:0051049;glucose homeostasis#GO:0042593;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;signal release#GO:0023061;peptide secretion#GO:0002790;localization#GO:0051179;regulation of secretion#GO:0051046;cell communication#GO:0007154;secretion#GO:0046903;peptide hormone secretion#GO:0030072;cellular response to stimulus#GO:0051716;protein localization to extracellular region#GO:0071692;homeostatic process#GO:0042592;transport#GO:0006810;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular protein localization#GO:0008104;cellular homeostasis#GO:0019725;establishment of protein localization to extracellular region#GO:0035592;macromolecule localization#GO:0033036;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;insulin secretion#GO:0030073;response to glucose#GO:0009749;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000008791.1|UniProtKB=W5MQP4 W5MQP4 PTHR24291:SF212 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 FAMILY 4 SUBFAMILY F MEMBER 11 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000000934.1|UniProtKB=W5LY73 W5LY73 PTHR24343:SF540 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE CHK1 catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000006427.1|UniProtKB=W5MHA6 W5MHA6 PTHR19143:SF40 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 7 animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;visual system development#GO:0150063;regulation of vasculature development#GO:1901342;sensory organ development#GO:0007423;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010423.1|UniProtKB=W5MWM4 W5MWM4 PTHR11377:SF14 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;localization within membrane#GO:0051668;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009352.1|UniProtKB=W5MSP8 W5MSP8 PTHR24248:SF21 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-2 ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;cation binding#GO:0043169;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 regulation of biological quality#GO:0065008;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;signaling#GO:0023052;vasodilation#GO:0042311;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system process#GO:0003008;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of anatomical structure size#GO:0090066;biological regulation#GO:0065007;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Beta2 adrenergic receptor signaling pathway#P04378>Beta2#P04440 LEPOC|Ensembl=ENSLOCG00000003442.1|UniProtKB=W5M6R9 W5M6R9 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000004982.1|UniProtKB=W5MC85 W5MC85 PTHR24330:SF4 HOMEOBOX PROTEIN BARH-LIKE BARH-LIKE 2 HOMEOBOX PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000010977.1|UniProtKB=W5MYL2 W5MYL2 PTHR12546:SF37 FER-1-LIKE FER-1-LIKE PROTEIN 6 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;membrane organization#GO:0061024;endomembrane system organization#GO:0010256 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000011423.1|UniProtKB=W5N080 W5N080 PTHR24347:SF442 SERINE/THREONINE-PROTEIN KINASE DEATH-ASSOCIATED PROTEIN KINASE 1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011615.1|UniProtKB=W5N0W8 W5N0W8 PTHR48034:SF14 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG ALPHA RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007974.1|UniProtKB=W5MMR9 W5MMR9 PTHR34753:SF1 TELOMERASE RNA COMPONENT INTERACTING RNASE TELOMERASE RNA COMPONENT-INTERACTING RNASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008795.1|UniProtKB=W5MQQ1 W5MQQ1 PTHR13856:SF31 VHS DOMAIN CONTAINING PROTEIN FAMILY TOM1-LIKE PROTEIN 2 clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular vesicle#GO:0097708;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000007771.1|UniProtKB=W5MM43 W5MM43 PTHR32073:SF6 GH11358P DIVERGENT PROTEIN KINASE DOMAIN 2A negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;regulation of apoptotic process#GO:0042981;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896 cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;COPI-coated vesicle#GO:0030137;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000008246.1|UniProtKB=W5MNQ3 W5MNQ3 PTHR13693:SF2 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 1 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;ceramide metabolic process#GO:0006672;sphingoid biosynthetic process#GO:0046520;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000000540.1|UniProtKB=W5LWT7 W5LWT7 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cell communication#GO:0007154;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015714.1|UniProtKB=W5NFD5 W5NFD5 PTHR15323:SF6 D123 PROTEIN TRANSLATION INITIATION FACTOR EIF2 ASSEMBLY PROTEIN cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005570.1|UniProtKB=W5MED5 W5MED5 PTHR11255:SF43 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ZETA transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;biosynthetic process#GO:0009058;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;neutral lipid metabolic process#GO:0006638;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 kinase#PC00137;metabolite interconversion enzyme#PC00262 Gonadotropin-releasing hormone receptor pathway#P06664>DGK-zeta#P06790 LEPOC|Ensembl=ENSLOCG00000011017.1|UniProtKB=W5MYQ8 W5MYQ8 PTHR21436:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 142 COILED-COIL DOMAIN-CONTAINING PROTEIN 142 LEPOC|Ensembl=ENSLOCG00000004617.1|UniProtKB=W5MAX5 W5MAX5 PTHR12896:SF1 PAX6 NEIGHBOR PROTEIN PAXNEB ELONGATOR COMPLEX PROTEIN 4 RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 elongator holoenzyme complex#GO:0033588;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000017064.1|UniProtKB=W5NKD0 W5NKD0 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED reverse transcriptase#PC00200;viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000009299.1|UniProtKB=W5MSI6 W5MSI6 PTHR24339:SF67 HOMEOBOX PROTEIN EMX-RELATED GNOT2 HOMEODOMAIN PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015103.1|UniProtKB=W5ND77 W5ND77 PTHR21016:SF4 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 2 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of Notch signaling pathway#GO:0045747;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056 LEPOC|Ensembl=ENSLOCG00000006903.1|UniProtKB=W5MIY9 W5MIY9 PTHR23036:SF109 CYTOKINE RECEPTOR LEPTIN RECEPTOR cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012213.1|UniProtKB=W5N313 W5N313 PTHR31586:SF1 CYTOCHROME C OXIDASE PROTEIN 20 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015277.1|UniProtKB=W5NDT8 W5NDT8 PTHR15953:SF1 APELIN APELIN LEPOC|Ensembl=ENSLOCG00000002399.1|UniProtKB=W5M348 W5M348 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005541.1|UniProtKB=W5MEA2 W5MEA2 PTHR10264:SF115 BAND 7 PROTEIN-RELATED STOMATIN transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000018320.1|UniProtKB=W5NP62 W5NP62 PTHR18884:SF128 SEPTIN SI:CH211-282J17.13-RELATED hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301;macromolecule localization#GO:0033036;cell cycle#GO:0007049;intracellular protein localization#GO:0008104;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cell cortex#GO:0005938;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000001972.1|UniProtKB=W5M1P0 W5M1P0 PTHR11347:SF135 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4C cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000016394.1|UniProtKB=W5NHY7 W5NHY7 PTHR10159:SF299 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 10 hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of JNK cascade#GO:0046328;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein phosphatase#PC00195 p38 MAPK pathway#P05918>MKP5#P05921;Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000016095.1|UniProtKB=W5NGS6 W5NGS6 PTHR11223:SF2 EXPORTIN 1/5 EXPORTIN-1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;transport#GO:0006810;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit export from nucleus#GO:0000055 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004043.1|UniProtKB=W5M8W8 W5M8W8 PTHR13486:SF2 TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER SPLICING FACTOR C9ORF78 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000008908.1|UniProtKB=W5MR41 W5MR41 PTHR15151:SF2 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 immune system process#GO:0002376;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;regulation of lymphocyte activation#GO:0051249;response to stimulus#GO:0050896;positive regulation of leukocyte activation#GO:0002696;regulation of B cell proliferation#GO:0030888;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of leukocyte proliferation#GO:0070663;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;lymphocyte homeostasis#GO:0002260;regulation of B cell activation#GO:0050864;regulation of mononuclear cell proliferation#GO:0032944;regulation of multicellular organismal process#GO:0051239;positive regulation of lymphocyte proliferation#GO:0050671;homeostasis of number of cells#GO:0048872;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;homeostatic process#GO:0042592;positive regulation of B cell proliferation#GO:0030890;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of leukocyte proliferation#GO:0070665;multicellular organismal-level homeostasis#GO:0048871;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of lymphocyte proliferation#GO:0050670 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000005766.1|UniProtKB=W5MF06 W5MF06 PTHR24229:SF1 NEUROPEPTIDES RECEPTOR KAPPA-TYPE OPIOID RECEPTOR molecular transducer activity#GO:0060089;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;binding#GO:0005488;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;system process#GO:0003008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;sensory perception of pain#GO:0019233;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 Opioid prodynorphin pathway#P05916>Kappa Receptor#P05998;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000009308.1|UniProtKB=W5MSJ3 W5MSJ3 PTHR24243:SF3 G-PROTEIN COUPLED RECEPTOR MOTILIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013977.1|UniProtKB=W5N9B8 W5N9B8 PTHR22916:SF73 GLYCOSYLTRANSFERASE QUEUOSINE-TRNA GALACTOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;galactosyltransferase activity#GO:0008378;catalytic activity, acting on a tRNA#GO:0140101 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000014170.1|UniProtKB=W5NA03 W5NA03 PTHR14149:SF15 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP1 actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;cytoskeletal protein binding#GO:0008092;calmodulin binding#GO:0005516;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actomyosin contractile ring assembly#GO:0000915;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;response to stimulus#GO:0050896;signaling#GO:0023052;actomyosin structure organization#GO:0031032;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;cytoskeleton-dependent cytokinesis#GO:0061640;ERBB signaling pathway#GO:0038127;cell migration#GO:0016477;epidermal growth factor receptor signaling pathway#GO:0007173;biological regulation#GO:0065007;mitotic cell cycle process#GO:1903047;actin filament organization#GO:0007015;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;cell division#GO:0051301;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;cortical cytoskeleton organization#GO:0030865;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;actin filament-based process#GO:0030029;cell communication#GO:0007154;cortical actin cytoskeleton organization#GO:0030866;enzyme-linked receptor protein signaling pathway#GO:0007167;mitotic cytokinetic process#GO:1902410;supramolecular fiber organization#GO:0097435 cell cortex#GO:0005938;nucleus#GO:0005634;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000001325.1|UniProtKB=W5LZH7 W5LZH7 PTHR24083:SF100 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-GAMMA sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;intracellular receptor signaling pathway#GO:0030522;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000016725.1|UniProtKB=W5NJ55 W5NJ55 PTHR13943:SF79 HRAS-LIKE SUPPRESSOR - RELATED HYPOTHETICAL LOC794087 hydrolase activity#GO:0016787;acyltransferase activity#GO:0016746;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;A2-type glycerophospholipase activity#GO:0004623;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008233.1|UniProtKB=W5MNN8 W5MNN8 PTHR24416:SF132 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR2 transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;Wnt-protein binding#GO:0017147;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 signaling receptor complex#GO:0043235;axon#GO:0030424;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005375.1|UniProtKB=W5MDP2 W5MDP2 PTHR10465:SF1 TRANSMEMBRANE GTPASE FZO1 MITOFUSIN-2 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 organelle localization#GO:0051640;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;mitochondrion localization#GO:0051646;cellular component organization#GO:0016043;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005 organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000009251.1|UniProtKB=W5MSC8 W5MSC8 PTHR22897:SF6 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE 1 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;protein-disulfide reductase activity#GO:0015035;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;intramolecular oxidoreductase activity#GO:0016860;disulfide oxidoreductase activity#GO:0015036;isomerase activity#GO:0016853 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;extracellular matrix assembly#GO:0085029;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;protein folding#GO:0006457;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006772.1|UniProtKB=W5MIG8 W5MIG8 PTHR10706:SF160 F-BOX FAMILY PROTEIN F-BOX ONLY PROTEIN 39 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004961.1|UniProtKB=W5MC56 W5MC56 PTHR24073:SF912 DRAB5-RELATED RAS-RELATED PROTEIN RAB-17 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;localization#GO:0051179;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;endocytosis#GO:0006897 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000006448.1|UniProtKB=W5MHE2 W5MHE2 PTHR15696:SF0 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 TELOMERASE-BINDING PROTEIN EST1A DNA binding#GO:0003677;RNA binding#GO:0003723;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000433.1|UniProtKB=W5LWG8 W5LWG8 PTHR19944:SF99 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ BETA 1 CHAIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823;protein-containing complex binding#GO:0044877 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of cellular process#GO:0048522;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;positive regulation of cell adhesion#GO:0045785;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;positive regulation of leukocyte activation#GO:0002696;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;regulation of multicellular organismal process#GO:0051239;regulation of T cell activation#GO:0050863;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;immune system process#GO:0002376;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249 lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vesicle#GO:0031982;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000001379.1|UniProtKB=W5LZK7 W5LZK7 PTHR23415:SF4 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 HOMOLOG cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009481.1|UniProtKB=W5MT80 W5MT80 PTHR45620:SF27 PDF RECEPTOR-LIKE PROTEIN-RELATED PARATHYROID HORMONE_PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;identical protein binding#GO:0042802;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;renal absorption#GO:0070293;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;system process#GO:0003008;cellular homeostasis#GO:0019725;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;chemical homeostasis#GO:0048878;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;signal transduction#GO:0007165;renal system process#GO:0003014;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001968.1|UniProtKB=W5M1L9 W5M1L9 PTHR45921:SF3 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 2 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000010196.1|UniProtKB=W5MVS6 W5MVS6 PTHR10165:SF26 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 1 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;signal transduction#GO:0007165;lipid modification#GO:0030258;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004456.1|UniProtKB=W5MAC1 W5MAC1 PTHR23003:SF6 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN M RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;nuclear mRNA surveillance#GO:0071028;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000015401.1|UniProtKB=W5NE99 W5NE99 PTHR11388:SF89 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B1 active transmembrane transporter activity#GO:0022804;bile acid transmembrane transporter activity#GO:0015125;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;secondary active transmembrane transporter activity#GO:0015291 lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;bile acid and bile salt transport#GO:0015721;lipid localization#GO:0010876 membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013324.1|UniProtKB=W5N726 W5N726 PTHR23346:SF19 TRANSLATIONAL ACTIVATOR GCN1-RELATED PROTEASOME ADAPTER AND SCAFFOLD PROTEIN ECM29 catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016155.1|UniProtKB=W5NH05 W5NH05 PTHR10846:SF78 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 3 passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000006783.1|UniProtKB=W5MII9 W5MII9 PTHR21328:SF3 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP8 catalytic activity#GO:0003824;protein kinase activator activity#GO:0030295;glycosyltransferase activity#GO:0016757;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209;pentosyltransferase activity#GO:0016763;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;transferase activity#GO:0016740;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 signal transduction#GO:0007165;cellular process#GO:0009987;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;biological regulation#GO:0065007;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum tubular network#GO:0071782;nucleus#GO:0005634;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000002991.1|UniProtKB=W5M571 W5M571 PTHR24056:SF508 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 10 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 mitotic cell cycle process#GO:1903047;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;mitotic cell cycle phase transition#GO:0044772;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016013.1|UniProtKB=W5NGG6 W5NGG6 PTHR10316:SF27 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor complex adaptor activity#GO:0030159;signaling adaptor activity#GO:0035591 signal transduction#GO:0007165;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;regulation of localization#GO:0032879;intracellular protein localization#GO:0008104;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;protein localization to membrane#GO:0072657;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;receptor clustering#GO:0043113;localization within membrane#GO:0051668;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641 dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054;adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000007045.1|UniProtKB=W5MJH6 W5MJH6 PTHR10648:SF7 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1 LIKE (PSEUDO structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000015129.1|UniProtKB=W5NDB1 W5NDB1 PTHR12241:SF31 TUBULIN POLYGLUTAMYLASE POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;binding#GO:0005488 male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000015932.1|UniProtKB=W5NG61 W5NG61 PTHR24020:SF91 COLLAGEN ALPHA VITRIN ISOFORM X1 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;cellular component organization#GO:0016043;positive regulation of cell-substrate adhesion#GO:0010811;cellular process#GO:0009987;positive regulation of cell adhesion#GO:0045785;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000010543.1|UniProtKB=W5MX08 W5MX08 PTHR11486:SF86 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 1 molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;response to fibroblast growth factor#GO:0071774;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 Angiogenesis#P00005>FGF#P00213;FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000015601.1|UniProtKB=W5NEZ9 W5NEZ9 PTHR11909:SF297 CASEIN KINASE-RELATED TAU-TUBULIN KINASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000018228.1|UniProtKB=W5NNX0 W5NNX0 PTHR14614:SF177 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009791.1|UniProtKB=W5MUB0 W5MUB0 PTHR15827:SF2 CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 Cell cycle#P00013>Cdk2#P00485 LEPOC|Ensembl=ENSLOCG00000017605.1|UniProtKB=W5NM51 W5NM51 PTHR13546:SF12 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85B regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000005818.1|UniProtKB=W5MF73 W5MF73 PTHR22957:SF27 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 13 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000008110.1|UniProtKB=W5MN92 W5MN92 PTHR23037:SF57 CYTOKINE RECEPTOR ERYTHROPOIETIN RECEPTOR molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010075.1|UniProtKB=W5MVC0 W5MVC0 PTHR13066:SF2 BASIC LEUCINE ZIPPER NUCLEAR FACTOR 1 BLZF1 PROTEIN GOLGIN-45 localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;Golgi vesicle transport#GO:0048193;transport#GO:0006810;protein localization to cell periphery#GO:1990778;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004730.1|UniProtKB=W5MBC1 W5MBC1 PTHR46130:SF2 LAMGL DOMAIN-CONTAINING PROTEIN PAPPALYSIN-1 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012587.1|UniProtKB=W5N4E0 W5N4E0 PTHR13037:SF11 FORMIN FORMIN-1 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;nucleus#GO:0005634;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000002890.1|UniProtKB=W5M4T9 W5M4T9 PTHR12951:SF3 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG B binding#GO:0005488;lipid binding#GO:0008289 organelle assembly#GO:0070925;localization#GO:0051179;protein transport#GO:0015031;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 cilium#GO:0005929;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017570.1|UniProtKB=W5NM16 W5NM16 PTHR31974:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 3 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 3 cell differentiation#GO:0030154;response to stimulus#GO:0050896;establishment of organelle localization#GO:0051656;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;cellular pigmentation#GO:0033059;synaptic vesicle localization#GO:0097479;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;developmental pigmentation#GO:0048066;synaptic vesicle transport#GO:0048489;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular response to stimulus#GO:0051716;anterograde axonal transport#GO:0008089;localization#GO:0051179;pigmentation#GO:0043473;axonal transport#GO:0098930;organelle localization#GO:0051640;developmental maturation#GO:0021700;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle localization#GO:0051648;axo-dendritic transport#GO:0008088;vesicle cytoskeletal trafficking#GO:0099518;response to external stimulus#GO:0009605;anterograde synaptic vesicle transport#GO:0048490;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;developmental process#GO:0032502;transport#GO:0006810;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;BLOC-1 complex#GO:0031083 LEPOC|Ensembl=ENSLOCG00000003148.1|UniProtKB=W5M5S6 W5M5S6 PTHR15504:SF1 NASOPHARYNGEAL EPITHELIUM SPECIFIC PROTEIN 1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 45 regulation of microtubule-based process#GO:0032886;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;regulation of cell motility#GO:2000145;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;sperm motility#GO:0097722;regulation of microtubule-based movement#GO:0060632;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;cell motility#GO:0048870;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of locomotion#GO:0040012 intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;cytoplasmic microtubule#GO:0005881;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;sperm flagellum#GO:0036126;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 LEPOC|Ensembl=ENSLOCG00000004196.1|UniProtKB=W5M9F2 W5M9F2 PTHR48071:SF18 SRCR DOMAIN-CONTAINING PROTEIN SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN DMBT1 ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000016267.1|UniProtKB=W5NHF3 W5NHF3 PTHR28580:SF1 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5 gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;response to stimulus#GO:0050896;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIIH holo complex#GO:0005675;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000008087.1|UniProtKB=W5MN63 W5MN63 PTHR12533:SF6 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;calcineurin-NFAT signaling cascade#GO:0033173;calcineurin-mediated signaling#GO:0097720;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;calcium-mediated signaling#GO:0019722;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;intracellular signaling cassette#GO:0141124;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;B cell activation#P00010>NFAT#P00367;T cell activation#P00053>NFAT#P01294;Axon guidance mediated by netrin#P00009>NFAT#P00359;Wnt signaling pathway#P00057>NFAT#P01452 LEPOC|Ensembl=ENSLOCG00000010076.1|UniProtKB=W5MVB8 W5MVB8 PTHR23185:SF0 PROTEIN VIRILIZER HOMOLOG PROTEIN VIRILIZER HOMOLOG catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;methyltransferase complex#GO:0034708;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009528.1|UniProtKB=W5MTE3 W5MTE3 PTHR22633:SF1 NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2-RELATED NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2 signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system development#GO:0048731;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003887.1|UniProtKB=W5M8C8 W5M8C8 PTHR24178:SF21 MOLTING PROTEIN MLT-4 ANKYRIN REPEAT AND SOCS BOX PROTEIN 3 macromolecule localization#GO:0033036;localization#GO:0051179;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104 plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000010787.1|UniProtKB=W5MXV9 W5MXV9 PTHR45620:SF8 PDF RECEPTOR-LIKE PROTEIN-RELATED CALCITONIN RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 regulation of biological quality#GO:0065008;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;axon#GO:0030424 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001092.1|UniProtKB=W5LYM9 W5LYM9 PTHR14586:SF1 THIAMINE-TRIPHOSPHATASE THIAMINE-TRIPHOSPHATASE hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ion binding#GO:0043167;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;magnesium ion binding#GO:0000287;hydrolase activity#GO:0016787;metal ion binding#GO:0046872 pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 Thiamin metabolism#P02780>Thiamine triphosphatase#P03184 LEPOC|Ensembl=ENSLOCG00000007010.1|UniProtKB=W5MJC9 W5MJC9 PTHR45704:SF7 RAS-LIKE FAMILY MEMBER 11 RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR-LIKE PROTEIN ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000016927.1|UniProtKB=W5NJW5 W5NJW5 PTHR10231:SF66 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER CMP-SIALIC ACID TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleotide-sugar transmembrane transport#GO:0015780;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003583.1|UniProtKB=W5M791 W5M791 PTHR13602:SF2 UPF0488 PROTEIN C8ORF33 UPF0488 PROTEIN C8ORF33 LEPOC|Ensembl=ENSLOCG00000013210.1|UniProtKB=W5N6L6 W5N6L6 PTHR10778:SF8 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000004942.1|UniProtKB=W5MC50 W5MC50 PTHR19376:SF72 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014951.1|UniProtKB=W5NCP8 W5NCP8 PTHR23235:SF156 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUPPEL-LIKE FACTOR 18 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000004566.1|UniProtKB=W5MAQ6 W5MAQ6 PTHR46138:SF1 PROTEIN DR1 PROTEIN DR1 binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351 transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000006565.1|UniProtKB=W5MHS2 W5MHS2 PTHR10466:SF2 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE 2 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;protein metabolic process#GO:0019538 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;isomerase#PC00135;mutase#PC00160 Mannose metabolism#P02752>P-Mannose mutase#P03019 LEPOC|Ensembl=ENSLOCG00000014733.1|UniProtKB=W5NBZ7 W5NBZ7 PTHR46003:SF3 HOST CELL FACTOR HOST CELL FACTOR 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097 LEPOC|Ensembl=ENSLOCG00000007440.1|UniProtKB=W5MKW8 W5MKW8 PTHR12418:SF19 ACYL-COENZYME A THIOESTERASE THEM4 ACYL-COENZYME A THIOESTERASE THEM4 fatty acyl-CoA hydrolase activity#GO:0047617;catalytic activity#GO:0003824;acyl-CoA hydrolase activity#GO:0016289;deacylase activity#GO:0160215;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular component organization#GO:0016043;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological quality#GO:0065008;oxoacid metabolic process#GO:0043436;regulation of membrane permeability#GO:0090559;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;apoptotic mitochondrial changes#GO:0008637;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 esterase#PC00097;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018176.1|UniProtKB=W5NNR8 W5NNR8 PTHR24366:SF120 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 4-RELATED immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000007903.1|UniProtKB=W5MMJ2 W5MMJ2 PTHR10117:SF6 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 2 anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;sexual reproduction#GO:0019953;fertilization#GO:0009566;reproductive process#GO:0022414;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;single fertilization#GO:0007338;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000007992.1|UniProtKB=W5MMU8 W5MMU8 PTHR24365:SF26 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 18 ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of response to external stimulus#GO:0032101 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017749.1|UniProtKB=W5NMJ4 W5NMJ4 PTHR24230:SF53 G-PROTEIN COUPLED RECEPTOR UROTENSIN-2 RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006777.1|UniProtKB=W5MIH7 W5MIH7 PTHR10671:SF115 EPITHELIAL MEMBRANE PROTEIN-RELATED GERM CELL-SPECIFIC GENE 1-LIKE PROTEIN regulation of synaptic plasticity#GO:0048167;regulation of endocytosis#GO:0030100;regulation of neuronal synaptic plasticity#GO:0048168;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010051.1|UniProtKB=W5MV89 W5MV89 PTHR14140:SF3 E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED E3 UBIQUITIN-PROTEIN LIGASE UHRF2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-translational protein modification#GO:0043687;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;protein modification process#GO:0036211;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;protein modification by small protein conjugation or removal#GO:0070647;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010549.1|UniProtKB=W5MX20 W5MX20 PTHR22767:SF6 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 15, NATA AUXILIARY SUBUNIT enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000012750.1|UniProtKB=W5N4Y3 W5N4Y3 PTHR16134:SF32 F-BOX/TPR REPEAT PROTEIN POF3 S-PHASE KINASE-ASSOCIATED PROTEIN 2 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of DNA recombination#GO:0000018;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of double-strand break repair via homologous recombination#GO:0010569;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein metabolic process#GO:0019538;regulation of double-strand break repair#GO:2000779;primary metabolic process#GO:0044238;positive regulation of DNA metabolic process#GO:0051054;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of double-strand break repair#GO:2000781;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stress#GO:0080134;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014303.1|UniProtKB=W5NAF3 W5NAF3 PTHR14327:SF2 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT GAMMA CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT GAMMA-LIKE ISOFORM X1 motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000012299.1|UniProtKB=W5N3C6 W5N3C6 PTHR11909:SF519 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM DELTA protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein metabolic process#GO:0051246;spindle assembly#GO:0051225;positive regulation of biological process#GO:0048518;cell projection assembly#GO:0030031;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;cellular component assembly#GO:0022607;positive regulation of Wnt signaling pathway#GO:0030177;cytoskeleton organization#GO:0007010;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;positive regulation of proteasomal protein catabolic process#GO:1901800;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;response to stimulus#GO:0050896;cell projection organization#GO:0030030;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;cilium organization#GO:0044782;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of circadian rhythm#GO:0042752;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;regulation of response to stimulus#GO:0048583;spindle organization#GO:0007051;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;organelle assembly#GO:0070925;non-motile cilium assembly#GO:1905515;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;spindle#GO:0005819;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167 Parkinson disease#P00049>Casein kinase I#P01242;Circadian clock system#P00015>Casein kinase I#P00502;Wnt signaling pathway#P00057>Casein Kinase 1#P01460;CCKR signaling map#P06959>CK1delta/epsilon#P07089 LEPOC|Ensembl=ENSLOCG00000009511.1|UniProtKB=W5MTB7 W5MTB7 PTHR28629:SF4 TRIOKINASE/FMN CYCLASE TRIOKINASE_FMN CYCLASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cyclase#PC00079 LEPOC|Ensembl=ENSLOCG00000016810.1|UniProtKB=W5NJG8 W5NJG8 PTHR21339:SF0 RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 2 S-ADENOSYLMETHIONINE-DEPENDENT NUCLEOTIDE DEHYDRATASE RSAD2 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 response to virus#GO:0009615;regulation of immune response#GO:0050776;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to virus#GO:0051607;regulation of biological process#GO:0050789;response to external stimulus#GO:0009605;defense response#GO:0006952;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000006666.1|UniProtKB=W5MI43 W5MI43 PTHR23153:SF38 UBX-RELATED UBX DOMAIN-CONTAINING PROTEIN 6 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011937.1|UniProtKB=W5N225 W5N225 PTHR11177:SF406 CHITINASE ACIDIC MAMMALIAN CHITINASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000013832.1|UniProtKB=W5N8V4 W5N8V4 PTHR11447:SF6 CELLULAR TUMOR ANTIGEN P53 CELLULAR TUMOR ANTIGEN P53 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;cell death#GO:0008219;cellular response to stimulus#GO:0051716;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;intrinsic apoptotic signaling pathway#GO:0097193;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;regulation of apoptotic process#GO:0042981;positive regulation of transcription by RNA polymerase II#GO:0045944;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;positive regulation of macromolecule metabolic process#GO:0010604 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;P53-like transcription factor#PC00253 p53 pathway feedback loops 2#P04398>p53#P04668;Wnt signaling pathway#P00057>p53#P01430;Huntington disease#P00029>p53#P00797;p53 pathway#P00059>p53#P01485;p53 pathway by glucose deprivation#P04397>p53#P04640;P53 pathway feedback loops 1#P04392>p53#P04539;Apoptosis signaling pathway#P00006>p53#P00273;p53 pathway#P00059>p53#G04702 LEPOC|Ensembl=ENSLOCG00000012598.1|UniProtKB=W5N4F3 W5N4F3 PTHR23358:SF3 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET2 dioxygenase activity#GO:0051213;catalytic activity, acting on DNA#GO:0140097;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;myeloid cell differentiation#GO:0030099;cell development#GO:0048468;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;hemopoiesis#GO:0030097;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012950.1|UniProtKB=W5N5N8 W5N5N8 PTHR22419:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 172 COILED-COIL DOMAIN-CONTAINING PROTEIN 172 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013481.1|UniProtKB=W5N7M0 W5N7M0 PTHR11036:SF69 SEMAPHORIN SEMA DOMAIN-CONTAINING PROTEIN binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;taxis#GO:0042330;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000009833.1|UniProtKB=W5MUF9 W5MUF9 PTHR24418:SF61 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ITK_TSK phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 immune system process#GO:0002376;lymphocyte differentiation#GO:0030098;cell activation#GO:0001775;anatomical structure development#GO:0048856;leukocyte activation#GO:0045321;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;mononuclear cell differentiation#GO:1903131;cell differentiation#GO:0030154;cell development#GO:0048468;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular process#GO:0009987;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;T cell differentiation#GO:0030217;hemopoiesis#GO:0030097 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000014987.1|UniProtKB=W5NCU3 W5NCU3 PTHR24232:SF6 G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 10-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003129.1|UniProtKB=W5M5M6 W5M5M6 PTHR24247:SF108 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 5A molecular transducer activity#GO:0060089;serotonin binding#GO:0051378;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;heterocyclic compound binding#GO:1901363;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000015306.1|UniProtKB=W5NDX4 W5NDX4 PTHR14297:SF4 MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER XK-RELATED PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000006103.1|UniProtKB=W5MG62 W5MG62 PTHR23267:SF189 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR DELTA VARIABLE 3 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003621.1|UniProtKB=W5M7E1 W5M7E1 PTHR46551:SF1 SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;localization#GO:0051179;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001900.1|UniProtKB=W5M1E2 W5M1E2 PTHR11636:SF128 POU DOMAIN POU DOMAIN, CLASS 5, TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009798.1|UniProtKB=W5MUD3 W5MUD3 PTHR42884:SF7 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 5 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;peptide hormone processing#GO:0016486;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 LEPOC|Ensembl=ENSLOCG00000004288.1|UniProtKB=W5M9R4 W5M9R4 PTHR23288:SF4 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;cell-cell junction organization#GO:0045216;transcription by RNA polymerase II#GO:0006366;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;snRNA metabolic process#GO:0016073;regulation of DNA-templated transcription#GO:0006355;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;snRNA transcription#GO:0009301;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043 cell-cell junction#GO:0005911;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;cytoplasm#GO:0005737;plasma membrane#GO:0005886;apical junction complex#GO:0043296;apical part of cell#GO:0045177;tight junction#GO:0070160;cell junction#GO:0030054;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000001926.1|UniProtKB=W5M1H2 W5M1H2 PTHR20859:SF93 INTERFERON/INTERLEUKIN RECEPTOR CYTOKINE RECEPTOR FAMILY MEMBER B12-RELATED transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002596.1|UniProtKB=W5M3U2 W5M3U2 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013778.1|UniProtKB=W5N8N2 W5N8N2 PTHR21328:SF2 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP16 kinase activator activity#GO:0019209;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;nucleus#GO:0005634;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000002346.1|UniProtKB=W5M2Z7 W5M2Z7 PTHR12210:SF112 DULLARD PROTEIN PHOSPHATASE CTD SMALL PHOSPHATASE-LIKE PROTEIN 3 ISOFORM X1 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000011640.1|UniProtKB=W5N0Z4 W5N0Z4 PTHR16151:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;spindle#GO:0005819 LEPOC|Ensembl=ENSLOCG00000005918.1|UniProtKB=W5MFK6 W5MFK6 PTHR10336:SF6 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE EPSILON-1 phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;lipase activity#GO:0016298 organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;monoatomic ion transmembrane transport#GO:0034220;lipid metabolic process#GO:0006629;transport#GO:0006810;phosphatidylinositol metabolic process#GO:0046488;establishment of localization#GO:0051234;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;Ras protein signal transduction#GO:0007265;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;monoatomic cation transmembrane transport#GO:0098655;intracellular signaling cassette#GO:0141124;metabolic process#GO:0008152;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186;hydrolase#PC00121 Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 LEPOC|Ensembl=ENSLOCG00000015264.1|UniProtKB=W5NDS5 W5NDS5 PTHR10663:SF338 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 4 cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;cell projection membrane#GO:0031253;ruffle#GO:0001726 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000006266.1|UniProtKB=W5MGR7 W5MGR7 PTHR13167:SF39 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 2 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836 response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to mechanical stimulus#GO:0009612;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;biological regulation#GO:0065007;detection of mechanical stimulus#GO:0050982;regulation of membrane potential#GO:0042391;cellular response to abiotic stimulus#GO:0071214;regulation of biological quality#GO:0065008;response to external stimulus#GO:0009605 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000002816.1|UniProtKB=W5M4K4 W5M4K4 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016332.1|UniProtKB=W5NHQ2 W5NHQ2 PTHR44216:SF3 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012955.1|UniProtKB=W5N5R0 W5N5R0 PTHR31540:SF1 CENTROSOMAL PROTEIN OF 131 KDA CENTROSOMAL PROTEIN OF 131 KDA sperm motility#GO:0097722;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;microtubule-based transport#GO:0099111;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;intraciliary transport involved in cilium assembly#GO:0035735;cilium movement involved in cell motility#GO:0060294;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;intraciliary transport#GO:0042073;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;male gamete generation#GO:0048232;developmental process#GO:0032502;spermatogenesis#GO:0007283;transport#GO:0006810;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;sperm axoneme assembly#GO:0007288;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;establishment of localization#GO:0051234 LEPOC|Ensembl=ENSLOCG00000013114.1|UniProtKB=W5N694 W5N694 PTHR36960:SF1 SI:DKEY-32E6.3 HMG BOX DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012391.1|UniProtKB=W5N3P9 W5N3P9 PTHR10334:SF613 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 16 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000009378.1|UniProtKB=W5MSU1 W5MSU1 PTHR11890:SF47 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN ISOFORM X1 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007898.1|UniProtKB=W5MMI0 W5MMI0 PTHR36877:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 13 SMALL INTEGRAL MEMBRANE PROTEIN 13 LEPOC|Ensembl=ENSLOCG00000007723.1|UniProtKB=W5MLW4 W5MLW4 PTHR44733:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000546.1|UniProtKB=W5LWU5 W5LWU5 PTHR28579:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT CDC26 ANAPHASE-PROMOTING COMPLEX SUBUNIT CDC26 regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein K11-linked ubiquitination#GO:0070979;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000000921.1|UniProtKB=W5LY52 W5LY52 PTHR12619:SF17 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 cilium organization#GO:0044782;spermatid differentiation#GO:0048515;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;spermatid development#GO:0007286;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;male gamete generation#GO:0048232;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;plasma membrane bounded cell projection organization#GO:0120036;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000004815.1|UniProtKB=W5MBP0 W5MBP0 PTHR11347:SF96 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 7A cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005454.1|UniProtKB=W5MDX4 W5MDX4 PTHR45618:SF11 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED KIDNEY MITOCHONDRIAL CARRIER PROTEIN 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007952.1|UniProtKB=W5MMQ4 W5MMQ4 PTHR12992:SF11 NUDIX HYDROLASE MITOCHONDRIAL COENZYME A DIPHOSPHATASE NUDT8 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound catabolic process#GO:0044273;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004827.1|UniProtKB=W5MBP9 W5MBP9 PTHR11246:SF1 PRE-MRNA SPLICING FACTOR PRE-MRNA-PROCESSING FACTOR 6 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000012140.1|UniProtKB=W5N2S3 W5N2S3 PTHR22618:SF2 PROTEIN O-MANNOSE KINASE PROTEIN O-MANNOSE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000018081.1|UniProtKB=W5NNH3 W5NNH3 PTHR24237:SF37 G-PROTEIN COUPLED RECEPTOR COAGULATION FACTOR II (THROMBIN) RECEPTOR-LIKE 2-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015760.1|UniProtKB=W5NFJ4 W5NFJ4 PTHR43157:SF59 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 13 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 visual system development#GO:0150063;animal organ morphogenesis#GO:0009887;primary metabolic process#GO:0044238;system development#GO:0048731;isoprenoid metabolic process#GO:0006720;anatomical structure development#GO:0048856;terpenoid metabolic process#GO:0006721;camera-type eye development#GO:0043010;multicellular organismal process#GO:0032501;camera-type eye morphogenesis#GO:0048593;diterpenoid metabolic process#GO:0016101;neurogenesis#GO:0022008;retinoid metabolic process#GO:0001523;cellular developmental process#GO:0048869;developmental process#GO:0032502;lipid metabolic process#GO:0006629;sensory organ development#GO:0007423;cell development#GO:0048468;cell differentiation#GO:0030154;sensory organ morphogenesis#GO:0090596;anatomical structure morphogenesis#GO:0009653;eye development#GO:0001654;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;olefinic compound metabolic process#GO:0120254;nervous system development#GO:0007399;retina development in camera-type eye#GO:0060041;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;sensory system development#GO:0048880;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;metabolic process#GO:0008152 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000012467.1|UniProtKB=W5N3Z1 W5N3Z1 PTHR45732:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8A intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;endosomal transport#GO:0016197;axo-dendritic transport#GO:0008088;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle-mediated transport#GO:0016192;lysosomal transport#GO:0007041;axonal transport#GO:0098930;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;anterograde axonal transport#GO:0008089;microtubule-based movement#GO:0007018 lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774 LEPOC|Ensembl=ENSLOCG00000007301.1|UniProtKB=W5MKD2 W5MKD2 PTHR34072:SF66 ENZYMATIC POLYPROTEIN-RELATED REVERSE TRANSCRIPTASE LEPOC|Ensembl=ENSLOCG00000015124.1|UniProtKB=W5NDA5 W5NDA5 PTHR11471:SF57 TUMOR NECROSIS FACTOR FAMILY MEMBER CD40 LIGAND ISOFORM X1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016991.1|UniProtKB=W5NK44 W5NK44 PTHR11360:SF119 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 10 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 transport#GO:0006810;hormone transport#GO:0009914;regulation of hormone levels#GO:0010817;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008914.1|UniProtKB=W5MR47 W5MR47 PTHR19248:SF32 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY E MEMBER 1 transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;cation binding#GO:0043169;ribonucleoprotein complex binding#GO:0043021;nucleotide binding#GO:0000166;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;metal ion binding#GO:0046872;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;iron ion binding#GO:0005506;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 translation#GO:0006412;translational initiation#GO:0006413;translational termination#GO:0006415;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000005107.1|UniProtKB=W5MCP3 W5MCP3 PTHR45046:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000511.1|UniProtKB=W5LWQ6 W5LWQ6 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED SI:DKEYP-69E1.8 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000003931.1|UniProtKB=W5M8I6 W5M8I6 PTHR11848:SF145 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 10 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000008824.1|UniProtKB=W5MQT3 W5MQT3 PTHR21506:SF0 COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6 cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;organelle organization#GO:0006996;retrograde transport, vesicle recycling within Golgi#GO:0000301;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;COG complex#GO:0017119;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000003957.1|UniProtKB=W5M8L9 W5M8L9 PTHR13000:SF0 NUCLEOPORIN P54 NUCLEOPORIN P54 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 macromolecule localization#GO:0033036;import into nucleus#GO:0051170;organelle organization#GO:0006996;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;nucleus organization#GO:0006997;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;nucleocytoplasmic transport#GO:0006913;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear pore organization#GO:0006999;protein import into nucleus#GO:0006606;protein transport#GO:0015031 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009717.1|UniProtKB=W5MU08 W5MU08 PTHR24246:SF52 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A1-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015270.1|UniProtKB=W5NDT1 W5NDT1 PTHR48069:SF5 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;tetrahydrofolate biosynthetic process#GO:0046654;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000011357.1|UniProtKB=W5MZZ8 W5MZZ8 PTHR16181:SF14 PROTEIN FAM83A-RELATED FAM83FA protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 LEPOC|Ensembl=ENSLOCG00000010414.1|UniProtKB=W5MWL0 W5MWL0 PTHR11487:SF0 THIOESTERASE S-ACYL FATTY ACID SYNTHASE THIOESTERASE, MEDIUM CHAIN biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 esterase#PC00097;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010492.1|UniProtKB=W5MWV5 W5MWV5 PTHR21277:SF5 TRANSCRIPTIONAL ADAPTER 1 TRANSCRIPTIONAL ADAPTER 1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;SAGA complex#GO:0000124;chromatin#GO:0000785 LEPOC|Ensembl=ENSLOCG00000010533.1|UniProtKB=W5MWZ5 W5MWZ5 PTHR23351:SF14 FOS TRANSCRIPTION FACTOR-RELATED BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000002488.1|UniProtKB=W5M3H3 W5M3H3 PTHR11920:SF464 GUANYLYL CYCLASE ATRIAL NATRIURETIC PEPTIDE RECEPTOR 1 ISOFORM X1 molecular transducer activity#GO:0060089;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653 organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 lyase#PC00144;guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000000764.1|UniProtKB=W5LXJ9 W5LXJ9 PTHR21274:SF1 MECKELIN MECKELIN organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 cilium#GO:0005929;ciliary transition zone#GO:0035869;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000018050.1|UniProtKB=W5NNE2 W5NNE2 PTHR11937:SF606 ACTIN ACTIN-3-LIKE structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 LEPOC|Ensembl=ENSLOCG00000005339.1|UniProtKB=W5MDH4 W5MDH4 PTHR18952:SF95 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 4 hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 cell periphery#GO:0071944;membrane#GO:0016020;apical plasma membrane#GO:0016324;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;apical part of cell#GO:0045177;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008114.1|UniProtKB=W5MNA3 W5MNA3 PTHR24372:SF68 GLYCOPROTEIN HORMONE RECEPTOR RELAXIN RECEPTOR 1 molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014529.1|UniProtKB=W5NB73 W5NB73 PTHR22629:SF0 ARP2/3 COMPLEX 20 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 LEPOC|Ensembl=ENSLOCG00000011297.1|UniProtKB=W5MZS6 W5MZS6 PTHR11949:SF9 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000003055.1|UniProtKB=W5M5D9 W5M5D9 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011892.1|UniProtKB=W5N1W7 W5N1W7 PTHR14677:SF37 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 1 cellular component organization or biogenesis#GO:0071840;organelle disassembly#GO:1903008;protein-RNA complex organization#GO:0071826;cellular component disassembly#GO:0022411;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex disassembly#GO:0032984 cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005993.1|UniProtKB=W5MFT2 W5MFT2 PTHR46105:SF6 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7A RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008139.1|UniProtKB=W5MNC3 W5MNC3 PTHR11532:SF45 PROTEASE M14 CARBOXYPEPTIDASE INACTIVE CARBOXYPEPTIDASE-LIKE PROTEIN X2 metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017682.1|UniProtKB=W5NMC8 W5NMC8 PTHR24228:SF52 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR RELAXIN FAMILY PEPTIDE_INSL5 RECEPTOR 4 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;animal organ development#GO:0048513;multicellular organism development#GO:0007275;response to chemical#GO:0042221;response to hormone#GO:0009725;response to stress#GO:0006950;renal system development#GO:0072001;kidney development#GO:0001822;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;response to nitrogen compound#GO:1901698;circulatory system process#GO:0003013;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;cellular response to stimulus#GO:0051716;defense response#GO:0006952;system process#GO:0003008;developmental process#GO:0032502;cellular response to nitrogen compound#GO:1901699;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of blood pressure#GO:0008217 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009130.1|UniProtKB=W5MRX3 W5MRX3 PTHR19857:SF27 MITOCHONDRIAL DIVISION PROTEIN 1-RELATED ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cell migration#GO:0016477;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 LEPOC|Ensembl=ENSLOCG00000012255.1|UniProtKB=W5N379 W5N379 PTHR11920:SF500 GUANYLYL CYCLASE GUANYLATE CYCLASE 2G lyase activity#GO:0016829;molecular transducer activity#GO:0060089;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 lyase#PC00144;guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000017061.1|UniProtKB=W5NKC6 W5NKC6 PTHR22974:SF21 MIXED LINEAGE PROTEIN KINASE DUAL SPECIFICITY PROTEIN KINASE TTK protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;sexual reproduction#GO:0019953;negative regulation of chromosome organization#GO:2001251;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of reproductive process#GO:2000241;regulation of mitotic cell cycle#GO:0007346;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;meiotic cell cycle process#GO:1903046;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of cell cycle#GO:0045786;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;meiotic cell cycle#GO:0051321;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of sister chromatid segregation#GO:0033046 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005488.1|UniProtKB=W5ME16 W5ME16 PTHR11991:SF23 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 regulation of programmed cell death#GO:0043067;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of metabolic process#GO:0009892;negative regulation of signaling#GO:0023057;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of cell communication#GO:0010648;negative regulation of catabolic process#GO:0009895;regulation of metabolic process#GO:0019222;negative regulation of programmed cell death#GO:0043069;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010931.1|UniProtKB=W5MYE8 W5MYE8 PTHR13082:SF0 SAP18 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 Hedgehog signaling pathway#P00025>Sap18#P00697 LEPOC|Ensembl=ENSLOCG00000013206.1|UniProtKB=W5N6K5 W5N6K5 PTHR13072:SF0 DYNACTIN 6 DYNACTIN SUBUNIT 6 binding#GO:0005488;protein-containing complex binding#GO:0044877 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle process#GO:0022402 cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000013730.1|UniProtKB=W5N8H7 W5N8H7 PTHR10151:SF66 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE CHOLINEPHOSPHODIESTERASE ENPP6 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008926.1|UniProtKB=W5MR58 W5MR58 PTHR12936:SF0 ANAPHASE-PROMOTING COMPLEX 10 ANAPHASE-PROMOTING COMPLEX SUBUNIT 10 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;cell cycle#GO:0007049;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 Cell cycle#P00013>APC#P00481 LEPOC|Ensembl=ENSLOCG00000000875.1|UniProtKB=W5LXX0 W5LXX0 PTHR23236:SF120 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4H RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000009207.1|UniProtKB=W5MS79 W5MS79 PTHR23158:SF38 MELANOMA INHIBITORY ACTIVITY-RELATED MELANOMA INHIBITORY ACTIVITY PROTEIN 2 protein secretion#GO:0009306;localization#GO:0051179;cellular localization#GO:0051641;secretion#GO:0046903;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;secretion by cell#GO:0032940;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003027.1|UniProtKB=W5M5F5 W5M5F5 PTHR12877:SF16 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 10-LIKE PROTEIN enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of actin filament-based process#GO:0032970;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;SREBP signaling pathway#GO:0032933;biological regulation#GO:0065007;actin filament-based process#GO:0030029;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular response to stress#GO:0033554;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000003331.1|UniProtKB=W5M6K9 W5M6K9 PTHR46877:SF11 EPH RECEPTOR A5 EPHRIN TYPE-B RECEPTOR 2 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 PDGF signaling pathway#P00047>PDGF receptor B#P01156;Angiogenesis#P00005>EphR#P00212 LEPOC|Ensembl=ENSLOCG00000015576.1|UniProtKB=W5NEW8 W5NEW8 PTHR47981:SF3 RAB FAMILY RAB7B, MEMBER RAS ONCOGENE FAMILY-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular component organization#GO:0016043;endocytosis#GO:0006897;vesicle fusion#GO:0006906;organelle assembly#GO:0070925;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membrane fusion#GO:0061025;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome organization#GO:0007040;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;phagolysosome assembly#GO:0001845;phagocytosis#GO:0006909;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;lytic vacuole organization#GO:0080171;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle organization#GO:0016050 lytic vacuole#GO:0000323;late endosome#GO:0005770;phagocytic vesicle#GO:0045335;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000000987.1|UniProtKB=W5LYA5 W5LYA5 PTHR11461:SF27 SERINE PROTEASE INHIBITOR, SERPIN SERPIN H1 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000006053.1|UniProtKB=W5MG48 W5MG48 PTHR45943:SF1 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;axon guidance#GO:0007411;axon development#GO:0061564;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;regulation of synapse organization#GO:0050807;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004503.1|UniProtKB=W5MAQ8 W5MAQ8 PTHR24006:SF678 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 28 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 negative regulation of cell cycle#GO:0045786;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;cell cycle checkpoint signaling#GO:0000075;regulation of protein stability#GO:0031647;signal transduction#GO:0007165;cellular process#GO:0009987;DNA integrity checkpoint signaling#GO:0031570;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell communication#GO:0007154;cellular response to stress#GO:0033554;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000005719.1|UniProtKB=W5MEU2 W5MEU2 PTHR45925:SF2 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 536 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000000950.1|UniProtKB=W5LY54 W5LY54 PTHR19375:SF169 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 13 ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072;Hsp70 family chaperone#PC00027 LEPOC|Ensembl=ENSLOCG00000000755.1|UniProtKB=W5LXH9 W5LXH9 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012831.1|UniProtKB=W5N584 W5N584 PTHR46218:SF2 LASP LIM AND SH3 DOMAIN PROTEIN 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 LEPOC|Ensembl=ENSLOCG00000018155.1|UniProtKB=W5NNP7 W5NNP7 PTHR11309:SF86 FRIZZLED FRIZZLED-10 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;non-canonical Wnt signaling pathway#GO:0035567;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 LEPOC|Ensembl=ENSLOCG00000011543.1|UniProtKB=W5N0M2 W5N0M2 PTHR13291:SF1 JOSEPHIN 1, 2 JOSEPHIN-1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824 protein modifying enzyme#PC00260;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000012307.1|UniProtKB=W5N3D1 W5N3D1 PTHR11360:SF27 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 4 proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;monocarboxylic acid transmembrane transporter activity#GO:0008028;active transmembrane transporter activity#GO:0022804;solute:proton symporter activity#GO:0015295;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017934.1|UniProtKB=W5NN28 W5NN28 PTHR13639:SF2 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016395.1|UniProtKB=W5NHY8 W5NHY8 PTHR11036:SF22 SEMAPHORIN SEMAPHORIN-3E signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;taxis#GO:0042330;response to chemical#GO:0042221;chemotaxis#GO:0006935;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000016075.1|UniProtKB=W5NGQ0 W5NGQ0 PTHR23167:SF43 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED EH DOMAIN-BINDING PROTEIN 1 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008124.1|UniProtKB=W5MNB1 W5MNB1 PTHR10161:SF29 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5-RELATED transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;acid phosphatase activity#GO:0003993;catalytic activity#GO:0003824;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506;phosphoric ester hydrolase activity#GO:0042578 tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;bone resorption#GO:0045453;bone remodeling#GO:0046849;homeostatic process#GO:0042592;tissue remodeling#GO:0048771;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000018034.1|UniProtKB=W5NNC6 W5NNC6 PTHR24248:SF136 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(1B) DOPAMINE RECEPTOR postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;response to nitrogen compound#GO:1901698;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948 LEPOC|Ensembl=ENSLOCG00000000864.1|UniProtKB=W5LXV6 W5LXV6 COQ4 PTHR12922:SF10 UBIQUINONE BIOSYNTHESIS PROTEIN UBIQUINONE BIOSYNTHESIS PROTEIN COQ4 HOMOLOG, MITOCHONDRIAL catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000002415.1|UniProtKB=W5M375 W5M375 PTHR28668:SF1 TRANSMEMBRANE PROTEIN 234 TRANSMEMBRANE PROTEIN 234 LEPOC|Ensembl=ENSLOCG00000015521.1|UniProtKB=W5NEQ3 W5NEQ3 PTHR10166:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-1 metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245 voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;sarcolemma#GO:0042383 transporter#PC00227;voltage-gated ion channel#PC00241 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>Ca2+ channel#P01081 LEPOC|Ensembl=ENSLOCG00000015548.1|UniProtKB=W5NET2 W5NET2 PTHR21860:SF2 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 6-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 6 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 protein-containing complex#GO:0032991;transcription factor TFIIIC complex#GO:0000127;transcription regulator complex#GO:0005667 LEPOC|Ensembl=ENSLOCG00000011774.1|UniProtKB=W5N1H5 W5N1H5 PTHR13634:SF0 RIBOSOME BIOGENESIS PROTEIN BRIX RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;cellular process#GO:0009987;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;organelle assembly#GO:0070925;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;protein-RNA complex assembly#GO:0022618 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012583.1|UniProtKB=W5N4D5 W5N4D5 PTHR11645:SF0 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 reductase#PC00198;metabolite interconversion enzyme#PC00262 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 LEPOC|Ensembl=ENSLOCG00000002393.1|UniProtKB=W5M3B8 W5M3B8 PTHR11199:SF2 STROMAL ANTIGEN COHESIN SUBUNIT SA binding#GO:0005488;chromatin binding#GO:0003682 sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001349.1|UniProtKB=W5LZI4 W5LZI4 PTHR47735:SF7 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016757.1|UniProtKB=W5NJA9 W5NJA9 PTHR12914:SF2 PARTNER OF SLD5 DNA REPLICATION COMPLEX GINS PROTEIN PSF1 cell cycle process#GO:0022402;DNA replication#GO:0006260;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA strand elongation involved in DNA replication#GO:0006271;mitotic cell cycle#GO:0000278;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170 organelle lumen#GO:0043233;chromosome#GO:0005694;DNA replication preinitiation complex#GO:0031261;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;organelle#GO:0043226;GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;CMG complex#GO:0071162;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000016358.1|UniProtKB=W5NHT9 W5NHT9 PTHR13322:SF2 C1ORF73 PROTEIN INTEGRATOR COMPLEX SUBUNIT 7 nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;DNA-templated transcription#GO:0006351;catabolic process#GO:0009056;DNA-templated transcription initiation#GO:0006352;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073 integrator complex#GO:0032039;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000016164.1|UniProtKB=W5NH08 W5NH08 PTHR24419:SF7 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 3 protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to molecule of bacterial origin#GO:0002237;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;positive regulation of signal transduction#GO:0009967;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cytokine-mediated signaling pathway#GO:0019221;lipopolysaccharide-mediated signaling pathway#GO:0031663;response to bacterium#GO:0009617 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>IRAKM#P01378 LEPOC|Ensembl=ENSLOCG00000012160.1|UniProtKB=W5N2U6 W5N2U6 PTHR19300:SF30 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 7 galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Wnt signaling pathway#P00057>Calcineurin#P01446 LEPOC|Ensembl=ENSLOCG00000004720.1|UniProtKB=W5MB99 W5MB99 PTHR46199:SF5 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell division#GO:0051301;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;intracellular signal transduction#GO:0035556;organelle assembly#GO:0070925;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052;signaling#GO:0023052;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;regulation of biological process#GO:0050789;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cytoskeleton-dependent cytokinesis#GO:0061640;Rho protein signal transduction#GO:0007266;cytokinesis#GO:0000910;nuclear division#GO:0000280;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;intracellular signaling cassette#GO:0141124;spindle elongation#GO:0051231;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;chromosome segregation#GO:0007059 spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular protein-containing complex#GO:0140535;cleavage furrow#GO:0032154;membraneless organelle#GO:0043228;nucleus#GO:0005634;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;cell division site#GO:0032153;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;midbody#GO:0030496;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000014145.1|UniProtKB=W5N9W7 W5N9W7 PTHR47421:SF1 GS HOMEOBOX 2 GS HOMEOBOX 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014138.1|UniProtKB=W5N9W3 W5N9W3 PTHR11679:SF92 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33B localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 lytic vacuole#GO:0000323;vesicle tethering complex#GO:0099023;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000013192.1|UniProtKB=W5N6I8 W5N6I8 PTHR14334:SF2 B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN BETA CHAIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;anatomical structure development#GO:0048856;lymphocyte differentiation#GO:0030098;regulation of immune response#GO:0050776;cell activation#GO:0001775;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;developmental process#GO:0032502;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;hemopoiesis#GO:0030097;immune response-regulating cell surface receptor signaling pathway#GO:0002768;immune system process#GO:0002376;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;cell development#GO:0048468;leukocyte differentiation#GO:0002521;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;mononuclear cell differentiation#GO:1903131;immune response-activating signaling pathway#GO:0002757;B cell activation#GO:0042113;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;lymphocyte activation#GO:0046649;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 B cell activation#P00010>Ig-beta#P00377 LEPOC|Ensembl=ENSLOCG00000009516.1|UniProtKB=W5MTC1 W5MTC1 PTHR23235:SF206 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 C2H2 zinc finger transcription factor#PC00248 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>EGR#P05931 LEPOC|Ensembl=ENSLOCG00000010085.1|UniProtKB=W5MVD1 W5MVD1 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001298.1|UniProtKB=W5LZB4 W5LZB4 PTHR12080:SF59 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE HEPATIC AND GLIAL CELL ADHESION MOLECULE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 localization#GO:0051179;cell communication#GO:0007154;intracellular protein localization#GO:0008104;immune system process#GO:0002376;protein localization to cell junction#GO:1902414;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;macromolecule localization#GO:0033036;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;regulation of biological process#GO:0050789 anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007221.1|UniProtKB=W5MK33 W5MK33 PTHR10005:SF3 SKI ONCOGENE-RELATED SKI-LIKE PROTEIN DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of DNA-templated transcription#GO:0045892;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of BMP signaling pathway#GO:0030510;negative regulation of macromolecule metabolic process#GO:0010605 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Gonadotropin-releasing hormone receptor pathway#P06664>SKIL#P06858 LEPOC|Ensembl=ENSLOCG00000016390.1|UniProtKB=W5NHZ7 W5NHZ7 PTHR46669:SF1 LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000000770.1|UniProtKB=W5LXK5 W5LXK5 PTHR47960:SF8 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 RNA HELICASE mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;P-body assembly#GO:0033962;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cytoplasmic stress granule assembly#GO:0034063;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organelle assembly#GO:0070925;negative regulation of translation#GO:0017148;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000015699.1|UniProtKB=W5NFB6 W5NFB6 PTHR16058:SF4 DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;neurogenesis#GO:0022008;sensory organ development#GO:0007423;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;sensory system development#GO:0048880;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;visual system development#GO:0150063;cell development#GO:0048468;anatomical structure morphogenesis#GO:0009653 LEPOC|Ensembl=ENSLOCG00000003314.1|UniProtKB=W5M6B5 W5M6B5 PTHR10026:SF64 CYCLIN CYCLIN-L1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000006837.1|UniProtKB=W5MIQ9 W5MIQ9 PTHR23359:SF58 NUCLEOTIDE KINASE ADENYLATE KINASE 4, MITOCHONDRIAL nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 LEPOC|Ensembl=ENSLOCG00000017206.1|UniProtKB=W5NKW3 W5NKW3 PTHR22948:SF7 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 15 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;cell maturation#GO:0048469;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulatory ncRNA-mediated gene silencing#GO:0031047;multicellular organismal process#GO:0032501;regionalization#GO:0003002;male gamete generation#GO:0048232;developmental maturation#GO:0021700;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;anterior/posterior axis specification#GO:0009948;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;cellular component assembly#GO:0022607;oogenesis#GO:0048477;embryo development#GO:0009790;RNA processing#GO:0006396;embryonic pattern specification#GO:0009880;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;P granule#GO:0043186;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017087.1|UniProtKB=W5NKF7 W5NKF7 PTHR44086:SF15 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000017420.1|UniProtKB=W5NLL6 W5NLL6 PTHR39158:SF1 OS08G0560600 PROTEIN DNAJ HEAT SHOCK PROTEIN FAMILY (HSP40) MEMBER C28 LEPOC|Ensembl=ENSLOCG00000002537.1|UniProtKB=W5M3M3 W5M3M3 PTHR11668:SF472 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE PP1-BETA CATALYTIC SUBUNIT hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of circadian rhythm#GO:0042752;circadian regulation of gene expression#GO:0032922;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;circadian rhythm#GO:0007623;regulation of biosynthetic process#GO:0009889;rhythmic process#GO:0048511 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969;Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602 LEPOC|Ensembl=ENSLOCG00000005294.1|UniProtKB=W5MDC2 W5MDC2 PTHR18887:SF4 GOLGI-ASSOCIATED PROTEIN GCP360-RELATED GOLGIN SUBFAMILY B MEMBER 1-LIKE LEPOC|Ensembl=ENSLOCG00000002833.1|UniProtKB=W5M4P4 W5M4P4 PTHR19957:SF97 SYNTAXIN SYNTAXIN-4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;membrane fusion#GO:0061025;exocytosis#GO:0006887;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle fusion#GO:0006906;export from cell#GO:0140352;cellular component organization#GO:0016043;secretion by cell#GO:0032940;protein transport#GO:0015031;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641 protein-containing complex#GO:0032991;SNARE complex#GO:0031201;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000014652.1|UniProtKB=W5NBM6 W5NBM6 PTHR24044:SF513 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004535.1|UniProtKB=W5MAL7 W5MAL7 PTHR10615:SF73 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT6B catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212;binding#GO:0005488;acetyltransferase activity#GO:0016407;transcription regulator activity#GO:0140110;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway#P00059>CBP#P04623 LEPOC|Ensembl=ENSLOCG00000012684.1|UniProtKB=W5N4Q3 W5N4Q3 PTHR13986:SF4 PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT ENDOPLASMIC RETICULUM PROTEIN SC65 protein-containing complex binding#GO:0044877;binding#GO:0005488;collagen binding#GO:0005518 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010820.1|UniProtKB=W5MY08 W5MY08 PTHR13190:SF20 AUTOPHAGY-RELATED 2, ISOFORM A AUTOPHAGY-RELATED PROTEIN 2 HOMOLOG B molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;protein-membrane adaptor activity#GO:0043495;lipid binding#GO:0008289 cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;carbohydrate metabolic process#GO:0005975;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;vacuole organization#GO:0007033;reticulophagy#GO:0061709;glycogen catabolic process#GO:0005980;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407 LEPOC|Ensembl=ENSLOCG00000015748.1|UniProtKB=W5NFH5 W5NFH5 PTHR24006:SF895 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001648.1|UniProtKB=W5M0L7 W5M0L7 PTHR11709:SF226 MULTI-COPPER OXIDASE CERULOPLASMIN oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000006258.1|UniProtKB=W5MGQ2 W5MGQ2 PTHR31915:SF5 SKICH DOMAIN-CONTAINING PROTEIN CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 LEPOC|Ensembl=ENSLOCG00000002832.1|UniProtKB=W5M4P2 W5M4P2 PTHR11037:SF6 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 3 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004981.1|UniProtKB=W5MC83 W5MC83 PTHR33772:SF1 THYMUS, BRAIN AND TESTES-ASSOCIATED PROTEIN TBATA LEPOC|Ensembl=ENSLOCG00000003402.1|UniProtKB=W5M6N3 W5M6N3 PTHR13131:SF14 CYSTINOSIN CYSTINOSIN L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;vacuolar transmembrane transport#GO:0034486;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 LEPOC|Ensembl=ENSLOCG00000005838.1|UniProtKB=W5MF88 W5MF88 PTHR21041:SF21 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DC-STAMP DOMAIN-CONTAINING PROTEIN 2 single fertilization#GO:0007338;sexual reproduction#GO:0019953;fertilization#GO:0009566;reproductive process#GO:0022414 LEPOC|Ensembl=ENSLOCG00000017097.1|UniProtKB=W5NKG9 W5NKG9 PTHR12289:SF76 METAXIN RELATED FAILED AXON CONNECTIONS HOMOLOG transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014133.1|UniProtKB=W5N9V0 W5N9V0 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 LEPOC|Ensembl=ENSLOCG00000009922.1|UniProtKB=W5MUS1 W5MUS1 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE LEPOC|Ensembl=ENSLOCG00000017875.1|UniProtKB=W5NMW9 W5NMW9 PTHR11636:SF115 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004407.1|UniProtKB=W5MA62 W5MA62 PTHR24253:SF191 TRANSMEMBRANE PROTEASE SERINE MATRIPTASE serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017417.1|UniProtKB=W5NLL3 W5NLL3 PTHR19957:SF29 SYNTAXIN SYNTAXIN-19 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization#GO:0016043;vesicle fusion#GO:0006906;export from cell#GO:0140352;localization#GO:0051179;cellular localization#GO:0051641;secretion#GO:0046903;secretion by cell#GO:0032940;protein transport#GO:0015031;membrane fusion#GO:0061025;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;exocytosis#GO:0006887;vesicle organization#GO:0016050 endomembrane system#GO:0012505;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000003892.1|UniProtKB=W5M8E9 W5M8E9 PTHR10292:SF7 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN 1 protein binding#GO:0005515;binding#GO:0005488;clathrin binding#GO:0030276 cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;receptor-mediated endocytosis#GO:0006898;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;mitotic cell cycle#GO:0000278;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;cell cycle#GO:0007049;cellular component organization#GO:0016043;localization#GO:0051179 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;clathrin-coated vesicle#GO:0030136;spindle#GO:0005819;clathrin-coated endocytic vesicle#GO:0045334;membraneless organelle#GO:0043228 vesicle coat protein#PC00235;membrane traffic protein#PC00150 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738 LEPOC|Ensembl=ENSLOCG00000013137.1|UniProtKB=W5N6C6 W5N6C6 PTHR15607:SF14 SYNAPTONEMAL COMPLEX PROTEIN-RELATED SYNAPTONEMAL COMPLEX PROTEIN 2-LIKE synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;synaptonemal structure#GO:0099086;membrane-enclosed lumen#GO:0031974;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000013564.1|UniProtKB=W5N7W5 W5N7W5 PTHR11315:SF10 PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE FOLATE GAMMA-GLUTAMYL HYDROLASE peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010427.1|UniProtKB=W5MWM9 W5MWM9 PTHR44177:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 8 TETRATRICOPEPTIDE REPEAT PROTEIN 8 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;BBSome#GO:0034464;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;cilium#GO:0005929;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000004895.1|UniProtKB=W5MC04 W5MC04 PTHR24304:SF0 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 7B1 steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;homeostatic process#GO:0042592;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cholesterol homeostasis#GO:0042632 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005244.1|UniProtKB=W5MD58 W5MD58 PTHR18875:SF3 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO CENTROSOMAL PROTEIN OF 63 KDA microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;cytoskeleton organization#GO:0007010;epithelium development#GO:0060429;cellular component assembly#GO:0022607;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003022.1|UniProtKB=W5M599 W5M599 PTHR11818:SF11 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B2 structural molecule activity#GO:0005198 sensory system development#GO:0048880;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004484.1|UniProtKB=W5MAF3 W5MAF3 UNG PTHR11264:SF0 URACIL-DNA GLYCOSYLASE URACIL-DNA GLYCOSYLASE hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;hydrolase activity#GO:0016787;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000004839.1|UniProtKB=W5MBQ5 W5MBQ5 PTHR43329:SF141 EPOXIDE HYDROLASE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED ether hydrolase activity#GO:0016803;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013311.1|UniProtKB=W5N707 W5N707 PTHR21229:SF19 LUNG SEVEN TRANSMEMBRANE RECEPTOR GOLGI-PH REGULATING CATION CHANNEL vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011410.1|UniProtKB=W5N071 W5N071 PTHR44054:SF1 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE NADPH-DEPENDENT QUINONE OXIDOREDUCTASE VAT1 negative regulation of cellular process#GO:0048523;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;biological regulation#GO:0065007 cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867 Huntington disease#P00029>PIG3#G01535 LEPOC|Ensembl=ENSLOCG00000017068.1|UniProtKB=W5NKD4 W5NKD4 PTHR22957:SF601 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 30 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005203.1|UniProtKB=W5MD32 W5MD32 PTHR11640:SF148 NEPHRIN ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE B cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001652.1|UniProtKB=W5M0N7 W5M0N7 PTHR45723:SF1 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE_THREONINE-PROTEIN KINASE RIO3 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467 cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005489.1|UniProtKB=W5ME12 W5ME12 PTHR13394:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;origin recognition complex#GO:0000808;membraneless organelle#GO:0043228;nuclear origin of replication recognition complex#GO:0005664;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000002386.1|UniProtKB=W5M342 W5M342 PTHR31179:SF8 RAB GTPASE-BINDING EFFECTOR PROTEIN RAB GTPASE-BINDING EFFECTOR PROTEIN 1 ISOFORM 1 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000006497.1|UniProtKB=W5MHI8 W5MHI8 PTHR13771:SF9 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 1 ISOFORM X1-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000003946.1|UniProtKB=W5M8K1 W5M8K1 PTHR33505:SF4 ZGC:162634 PROTEIN PREY, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000018180.1|UniProtKB=W5NNS2 W5NNS2 PTHR15258:SF2 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 1 binding#GO:0005488;growth factor binding#GO:0019838;protein binding#GO:0005515 cell communication#GO:0007154;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000006606.1|UniProtKB=W5MHX0 W5MHX0 PTHR13832:SF837 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1 protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000012335.1|UniProtKB=W5N3H2 W5N3H2 PTHR32178:SF7 FAM187 IG-LIKE V-TYPE DOMAIN-CONTAINING PROTEIN FAM187A immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000008236.1|UniProtKB=W5MNP1 W5MNP1 PTHR14499:SF10 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING POTASSIUM CHANNEL TETRAMERIZATION DOMAIN CONTAINING 6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011467.1|UniProtKB=W5N0E9 W5N0E9 PTHR23113:SF172 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1A enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000001043.1|UniProtKB=W5LYG3 W5LYG3 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013266.1|UniProtKB=W5N6T5 W5N6T5 PTHR23320:SF143 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED SUBFAMILY NOT NAMED transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013749.1|UniProtKB=W5N8K0 W5N8K0 PTHR31399:SF0 DNA-DIRECTED PRIMASE / POLYMERASE PROTEIN DNA-DIRECTED PRIMASE_POLYMERASE PROTEIN DNA-directed DNA polymerase activity#GO:0003887;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;macromolecule biosynthetic process#GO:0009059;response to radiation#GO:0009314;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;translesion synthesis#GO:0019985;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;response to UV#GO:0009411;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;mitochondrial DNA metabolic process#GO:0032042;DNA-templated DNA replication#GO:0006261;DNA synthesis involved in DNA replication#GO:0090592 mitochondrion#GO:0005739;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005798.1|UniProtKB=W5MF44 W5MF44 PTHR11960:SF17 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2 RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000011127.1|UniProtKB=W5MZ58 W5MZ58 PTHR10188:SF42 L-ASPARAGINASE ISOASPARTYL PEPTIDASE_L-ASPARAGINASE metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004831.1|UniProtKB=W5MBP2 W5MBP2 PTHR12081:SF40 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F8 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000012889.1|UniProtKB=W5N5F7 W5N5F7 PTHR36687:SF1 GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2-RELATED GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 LEPOC|Ensembl=ENSLOCG00000010658.1|UniProtKB=W5MXI5 W5MXI5 PTHR48015:SF2 SERINE/THREONINE-PROTEIN KINASE TAO MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 4 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCKR#P00311 LEPOC|Ensembl=ENSLOCG00000011466.1|UniProtKB=W5N0C5 W5N0C5 PTHR19300:SF5 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000005449.1|UniProtKB=W5MDW1 W5MDW1 PTHR11592:SF81 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000016857.1|UniProtKB=W5NJN1 W5NJN1 PTHR12844:SF17 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004134.1|UniProtKB=W5M983 W5M983 PTHR21017:SF14 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 process utilizing autophagic mechanism#GO:0061919;mitophagy#GO:0000423;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000004367.1|UniProtKB=W5MA21 W5MA21 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016213.1|UniProtKB=W5NH80 W5NH80 PTHR11347:SF72 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 7B hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000006491.1|UniProtKB=W5MHI7 W5MHI7 PTHR12858:SF1 RIBOSOME BIOGENESIS PROTEIN PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007243.1|UniProtKB=W5MK73 W5MK73 PTHR16059:SF13 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009066.1|UniProtKB=W5MRN7 W5MRN7 PTHR28607:SF1 EXPRESSED PROTEIN MEMBRANE PROTEIN FAM174A LEPOC|Ensembl=ENSLOCG00000010403.1|UniProtKB=W5MWL9 W5MWL9 PTHR13720:SF16 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 5 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008383.1|UniProtKB=W5MPB2 W5MPB2 PTHR24040:SF7 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN FIBRILLIN 2B cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000011689.1|UniProtKB=W5N159 W5N159 PTHR11267:SF211 T-BOX PROTEIN-RELATED MAX DIMERIZATION PROTEIN MGA A RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 LEPOC|Ensembl=ENSLOCG00000005954.1|UniProtKB=W5MFN1 W5MFN1 PTHR12271:SF140 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE GLD2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA destabilization#GO:0061157;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311;mRNA processing#GO:0006397;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000000187.1|UniProtKB=W5LVQ1 W5LVQ1 PTHR48112:SF12 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP BOX 1, PSEUDOGENE 34 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 p53 pathway#P00059>HMG1#P04619 LEPOC|Ensembl=ENSLOCG00000017386.1|UniProtKB=W5NLI2 W5NLI2 PTHR38505:SF1 HYPOTHETICAL PROTEIN LOC100362176 SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 80 LEPOC|Ensembl=ENSLOCG00000005991.1|UniProtKB=W5MFT5 W5MFT5 PTHR12183:SF6 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 RING-TYPE E3 UBIQUITIN TRANSFERASE positive regulation of developmental process#GO:0051094;protein stabilization#GO:0050821;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein stability#GO:0031647;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of mitochondrial fission#GO:0090140;regulation of developmental process#GO:0050793;positive regulation of mitochondrial fission#GO:0090141;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010082.1|UniProtKB=W5MVC1 W5MVC1 PTHR10485:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-A transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006725.1|UniProtKB=W5MIB1 W5MIB1 PTHR23167:SF37 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED SMOOTHELIN-LIKE PROTEIN 2 actin filament-based process#GO:0030029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017904.1|UniProtKB=W5NMZ8 W5NMZ8 PTHR24241:SF1 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 22 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017179.1|UniProtKB=W5NKS3 W5NKS3 PTHR16458:SF2 GLYCINE N-METHYLTRANSFERASE GLYCINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;carbohydrate derivative metabolic process#GO:1901135;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 methyltransferase#PC00155;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000002901.1|UniProtKB=W5M4W0 W5M4W0 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009925.1|UniProtKB=W5MUT0 W5MUT0 PTHR12259:SF4 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009694.1|UniProtKB=W5MTY0 W5MTY0 PTHR24246:SF52 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002197.1|UniProtKB=W5M2E9 W5M2E9 PTHR12198:SF9 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 PROSPERO HOMEOBOX PROTEIN 2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001257.1|UniProtKB=W5LZ71 W5LZ71 PTHR45640:SF14 HEAT SHOCK PROTEIN HSP-12.2-RELATED ALPHA-CRYSTALLIN A CHAIN negative regulation of cellular process#GO:0048523;sensory organ development#GO:0007423;developmental process#GO:0032502;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;biosynthetic process#GO:0009058;camera-type eye development#GO:0043010;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;system development#GO:0048731;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;visual system development#GO:0150063;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;lens development in camera-type eye#GO:0002088;animal organ development#GO:0048513;multicellular organism development#GO:0007275;response to stress#GO:0006950;sensory system development#GO:0048880;response to heat#GO:0009408;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;animal gross anatomical part developmental process#GO:0160108;eye development#GO:0001654;protein refolding#GO:0042026;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;protein folding#GO:0006457 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 LEPOC|Ensembl=ENSLOCG00000016201.1|UniProtKB=W5NH62 W5NH62 PTHR10736:SF2 BESTROPHIN BESTROPHIN-3 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011796.1|UniProtKB=W5N1L2 W5N1L2 PTHR45688:SF3 FAMILY NOT NAMED ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000004435.1|UniProtKB=W5MA92 W5MA92 PTHR14413:SF24 RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412 membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000015754.1|UniProtKB=W5NFI6 W5NFI6 PTHR28630:SF32 FAMILY NOT NAMED SELENOPROTEIN L oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;unsaturated fatty acid biosynthetic process#GO:0006636;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;prostaglandin metabolic process#GO:0006693;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009649.1|UniProtKB=W5MTT3 W5MTT3 PTHR24068:SF159 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 T acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;response to stimulus#GO:0050896;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000017148.1|UniProtKB=W5NKN3 W5NKN3 PTHR21528:SF0 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000002937.1|UniProtKB=W5M500 W5M500 PTHR46752:SF1 G-PROTEIN COUPLED RECEPTOR 39 G PROTEIN-COUPLED RECEPTOR 39 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of pH#GO:0006885;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;regulation of intracellular pH#GO:0051453;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008640.1|UniProtKB=W5MQ45 W5MQ45 PTHR24104:SF21 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 3 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>HAC1#P00131 LEPOC|Ensembl=ENSLOCG00000015648.1|UniProtKB=W5NF52 W5NF52 PTHR23282:SF153 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009509.1|UniProtKB=W5MTA7 W5MTA7 PTHR46608:SF2 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 T CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING 4 phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 apoptotic cell clearance#GO:0043277;localization#GO:0051179;endocytosis#GO:0006897;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;phagocytosis#GO:0006909 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014315.1|UniProtKB=W5NAH0 W5NAH0 PTHR11878:SF8 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER 2 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;export from cell#GO:0140352;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 postsynaptic membrane#GO:0045211;axon#GO:0030424;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;membrane#GO:0016020;presynapse#GO:0098793;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014430.1|UniProtKB=W5NAU9 W5NAU9 PTHR47410:SF3 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 9 signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;positive regulation of multicellular organismal process#GO:0051240;defense response to virus#GO:0051607;toll-like receptor signaling pathway#GO:0002224;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;immune system process#GO:0002376;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;response to other organism#GO:0051707;canonical NF-kappaB signal transduction#GO:0007249;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of gene expression#GO:0010628;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;intracellular signal transduction#GO:0035556;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;response to virus#GO:0009615 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000007020.1|UniProtKB=W5MJD9 W5MJD9 PTHR10519:SF80 GABA-B RECEPTOR G PROTEIN-COUPLED RECEPTOR 156-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052 signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005163.1|UniProtKB=W5MCV8 W5MCV8 PTHR15362:SF13 PHOSPHATIDYLINOSITOL SYNTHASE SI:CH1073-145M9.1 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016976.1|UniProtKB=W5NK24 W5NK24 PTHR10605:SF46 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 5 catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014298.1|UniProtKB=W5NAE4 W5NAE4 PTHR13327:SF0 NADH-UBIQUINONE OXIDOREDUCTASE ESSS SUBUNIT, MITOCHONDRIAL PRECURSOR NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 11, MITOCHONDRIAL membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014940.1|UniProtKB=W5NCP1 W5NCP1 PTHR14167:SF128 SH3 DOMAIN-CONTAINING SORBIN AND SH3 DOMAIN CONTAINING 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015947.1|UniProtKB=W5NG76 W5NG76 PTHR15427:SF61 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-1-A-RELATED cellular process#GO:0009987;cell adhesion mediated by integrin#GO:0033627;cell adhesion#GO:0007155 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016207.1|UniProtKB=W5NH68 W5NH68 PTHR15919:SF13 DAPPER-RELATED DAPPER HOMOLOG 2 negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000009411.1|UniProtKB=W5MSX6 W5MSX6 PTHR10926:SF68 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007824.1|UniProtKB=W5MM92 W5MM92 PTHR13401:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR1 RAGULATOR COMPLEX PROTEIN LAMTOR1 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to acid chemical#GO:0001101;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cellular response to amino acid stimulus#GO:0071230;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;positive regulation of signaling#GO:0023056 lysosome#GO:0005764;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323 LEPOC|Ensembl=ENSLOCG00000000606.1|UniProtKB=W5LX09 W5LX09 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002768.1|UniProtKB=W5M4E8 W5M4E8 URM1 PTHR14986:SF4 RURM1 PROTEIN UBIQUITIN-RELATED MODIFIER 1 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015571.1|UniProtKB=W5NEW3 W5NEW3 PTHR11227:SF29 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 4 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;vacuole organization#GO:0007033;localization#GO:0051179;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;phagophore assembly site#GO:0000407 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010455.1|UniProtKB=W5MWS9 W5MWS9 PTHR11908:SF86 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006515.1|UniProtKB=W5MHP3 W5MHP3 PTHR46393:SF8 SUSHI DOMAIN-CONTAINING PROTEIN COMPLEMENT C2 ISOFORM X1 response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to biotic stimulus#GO:0009607;immune response#GO:0006955;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;immune system process#GO:0002376 LEPOC|Ensembl=ENSLOCG00000010162.1|UniProtKB=W5MVN2 W5MVN2 PTHR22957:SF367 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 14 GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of autophagosome assembly#GO:2000785;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;recycling endosome#GO:0055037;autophagosome#GO:0005776;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000002163.1|UniProtKB=W5M2A8 W5M2A8 PTHR10219:SF20 GLYCOLIPID TRANSFER PROTEIN-RELATED CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN transporter activity#GO:0005215;phospholipid binding#GO:0005543;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;phospholipid transfer activity#GO:0120014;ion binding#GO:0043167;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;ceramide transport#GO:0035627;membrane organization#GO:0061024;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000000973.1|UniProtKB=W5LY85 W5LY85 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003455.1|UniProtKB=W5M6U4 W5M6U4 PTHR16320:SF26 SPHINGOMYELINASE FAMILY MEMBER SPHINGOMYELIN PHOSPHODIESTERASE 3 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;sphingomyelin metabolic process#GO:0006684;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004282.1|UniProtKB=W5M9Q7 W5M9Q7 PTHR31690:SF4 FUCOSE MUTAROTASE FUCOSE MUTAROTASE catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853;monosaccharide binding#GO:0048029;carbohydrate binding#GO:0030246;binding#GO:0005488;small molecule binding#GO:0036094 metabolic process#GO:0008152;hexose metabolic process#GO:0019318;monosaccharide metabolic process#GO:0005996;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975 LEPOC|Ensembl=ENSLOCG00000006341.1|UniProtKB=W5MGZ9 W5MGZ9 PTHR40446:SF2 N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE establishment of localization#GO:0051234;secretion#GO:0046903;protein secretion#GO:0009306;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;transport#GO:0006810;export from cell#GO:0140352;macromolecule localization#GO:0033036;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;establishment of protein localization#GO:0045184 LEPOC|Ensembl=ENSLOCG00000012952.1|UniProtKB=W5N5N9 W5N5N9 PTHR23064:SF29 TROPONIN PARVALBUMIN-LIKE EF-HAND-CONTAINING PROTEIN nervous system process#GO:0050877;neuromuscular process#GO:0050905;muscle contraction#GO:0006936;system process#GO:0003008;muscle system process#GO:0003012;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;multicellular organismal process#GO:0032501 intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sarcomere#GO:0030017;contractile muscle fiber#GO:0043292;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000010763.1|UniProtKB=W5MXT8 W5MXT8 PTHR10050:SF46 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 2 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011060.1|UniProtKB=W5MYX2 W5MYX2 PTHR17609:SF2 HMG DOMAIN-CONTAINING PROTEIN 3 HMG DOMAIN-CONTAINING PROTEIN 3 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000005136.1|UniProtKB=W5MCS7 W5MCS7 PTHR28556:SF5 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106C LEPOC|Ensembl=ENSLOCG00000007683.1|UniProtKB=W5MLR7 W5MLR7 PTHR46884:SF1 COLLECTRIN COLLECTRIN EGF receptor signaling pathway#P00018>Ras#P00552 LEPOC|Ensembl=ENSLOCG00000016005.1|UniProtKB=W5NGF6 W5NGF6 PTHR12025:SF5 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR A, LONG FORM molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 positive regulation of chemotaxis#GO:0050921;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of leukocyte migration#GO:0002685;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;positive regulation of locomotion#GO:0040017;response to hypoxia#GO:0001666;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;tube development#GO:0035295;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;angiogenesis#GO:0001525;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;blood vessel morphogenesis#GO:0048514;positive regulation of cell motility#GO:2000147;response to endogenous stimulus#GO:0009719;vascular endothelial growth factor receptor signaling pathway#GO:0048010;regulation of chemotaxis#GO:0050920;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of response to external stimulus#GO:0032103;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cell surface receptor signaling pathway#GO:0007166;regulation of response to external stimulus#GO:0032101;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 VEGF signaling pathway#P00056>VEGF#P01406;Angiogenesis#P00005>VEGF#P00241 LEPOC|Ensembl=ENSLOCG00000006092.1|UniProtKB=W5MG80 W5MG80 PTHR46459:SF1 E1A-BINDING PROTEIN P400-RELATED E1A-BINDING PROTEIN P400 binding#GO:0005488;chromatin binding#GO:0003682 nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nuclear chromosome#GO:0000228;H4 histone acetyltransferase complex#GO:1902562;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;acetyltransferase complex#GO:1902493 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000013239.1|UniProtKB=W5N6P5 W5N6P5 PTHR22704:SF2 BMERB DOMAIN-CONTAINING PROTEIN 1-RELATED BMERB DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000003920.1|UniProtKB=W5M8H3 W5M8H3 DIDO1 PTHR11477:SF13 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN DEATH-INDUCER OBLITERATOR 1 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000014102.1|UniProtKB=W5N9R8 W5N9R8 PTHR45922:SF2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000016301.1|UniProtKB=W5NHL4 W5NHL4 PTHR11361:SF156 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH2 nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;double-stranded DNA binding#GO:0003690;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;adaptive immune response#GO:0002250;somatic cell DNA recombination#GO:0016444;immune response#GO:0006955;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;DNA damage response#GO:0006974;developmental process#GO:0032502;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;system development#GO:0048731;mitotic recombination#GO:0006312;gene expression#GO:0010467;response to stress#GO:0006950;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;multicellular organism development#GO:0007275;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;immune effector process#GO:0002252;response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;mismatch repair#GO:0006298;leukocyte mediated immunity#GO:0002443;immune system development#GO:0002520;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;cellular response to stress#GO:0033554 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003094.1|UniProtKB=W5M5I6 W5M5I6 PTHR12760:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN ER MEMBRANE PROTEIN COMPLEX SUBUNIT 2 molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;protein localization to organelle#GO:0033365 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009785.1|UniProtKB=W5MU88 W5MU88 PTHR10628:SF22 SIALIDASE SIALIDASE-4 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;glycolipid metabolic process#GO:0006664 membrane#GO:0016020;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012478.1|UniProtKB=W5N401 W5N401 PTHR10491:SF6 DTDP-4-DEHYDRORHAMNOSE REDUCTASE METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 reductase#PC00198 O-antigen biosynthesis#P02757>dTDP-4-dehydrorhamnose reductase#P03050 LEPOC|Ensembl=ENSLOCG00000010479.1|UniProtKB=W5MWU4 W5MWU4 PTHR45915:SF3 TRANSCRIPTION INTERMEDIARY FACTOR E3 UBIQUITIN-PROTEIN LIGASE TRIM33 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;transcription regulator activity#GO:0140110;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001916.1|UniProtKB=W5M1G3 W5M1G3 PTHR14618:SF5 HOMEODOX-CONTAINING PROTEIN 1 HMBOX1 HOMEOBOX-CONTAINING PROTEIN 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015244.1|UniProtKB=W5NDP8 W5NDP8 PTHR33721:SF1 TRANSMEMBRANE PROTEIN 255B-LIKE TRANSMEMBRANE PROTEIN 255A LEPOC|Ensembl=ENSLOCG00000018175.1|UniProtKB=W5NNR7 W5NNR7 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002903.1|UniProtKB=W5M4V2 W5M4V2 PTHR13460:SF0 FAMILY NOT NAMED MALECTIN binding#GO:0005488;carbohydrate binding#GO:0030246 cellular process#GO:0009987;primary metabolic process#GO:0044238;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008407.1|UniProtKB=W5MPD0 W5MPD0 PTHR24212:SF1 ZYXIN/TRIP6 ZYXIN response to transforming growth factor beta#GO:0071559;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091 actin cytoskeleton#GO:0015629;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin filament bundle#GO:0032432;actomyosin#GO:0042641;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000011173.1|UniProtKB=W5MZB9 W5MZB9 PTHR42966:SF1 N-ACETYLNEURAMINATE SYNTHASE N-ACETYLNEURAMINATE-9-PHOSPHATE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008336.1|UniProtKB=W5MP15 W5MP15 PTHR46843:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 16 BTB_POZ DOMAIN-CONTAINING PROTEIN 16 LEPOC|Ensembl=ENSLOCG00000004753.1|UniProtKB=W5MBE1 W5MBE1 PTHR12398:SF20 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2 enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 phosphatase inhibitor#PC00183 LEPOC|Ensembl=ENSLOCG00000018363.1|UniProtKB=W5NPA5 W5NPA5 PTHR13976:SF87 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RNA BINDING MOTIF PROTEIN 12 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000008033.1|UniProtKB=W5MMZ4 W5MMZ4 PTHR36128:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 117 COILED-COIL DOMAIN-CONTAINING PROTEIN 117 LEPOC|Ensembl=ENSLOCG00000010732.1|UniProtKB=W5MXP0 W5MXP0 PTHR24056:SF130 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 6 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000783.1|UniProtKB=W5LXL1 W5LXL1 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 antigen binding#GO:0003823;binding#GO:0005488 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017737.1|UniProtKB=W5NMI2 W5NMI2 PTHR24070:SF269 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS3 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000018348.1|UniProtKB=W5NP90 W5NP90 PTHR15437:SF2 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR 1, MITOCHONDRIAL binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389;General transcription regulation#P00023>TTF2#P00661 LEPOC|Ensembl=ENSLOCG00000005035.1|UniProtKB=W5MCF6 W5MCF6 PTHR10044:SF163 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 7 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;enzyme regulator activity#GO:0030234;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755 regulation of protein modification process#GO:0031399;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of protein ubiquitination#GO:0031396;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012277.1|UniProtKB=W5N397 W5N397 PTHR12027:SF84 WNT RELATED PROTEIN WNT-9B molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125 signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell fate commitment#GO:0045165;system development#GO:0048731;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 LEPOC|Ensembl=ENSLOCG00000011247.1|UniProtKB=W5MZL1 W5MZL1 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016444.1|UniProtKB=W5NI57 W5NI57 PTHR11849:SF19 ETS TRANSCRIPTION FACTOR ETV6 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000008799.1|UniProtKB=W5MQQ0 W5MQQ0 PTHR24343:SF303 SERINE/THREONINE KINASE 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;response to stimulus#GO:0050896;negative regulation of TORC1 signaling#GO:1904262;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;negative regulation of signal transduction#GO:0009968;localization#GO:0051179;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;negative regulation of TOR signaling#GO:0032007;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;intracellular protein localization#GO:0008104;regulation of TORC1 signaling#GO:1903432;positive regulation of catabolic process#GO:0009896;cellular response to glucose starvation#GO:0042149;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;macromolecule localization#GO:0033036;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway by glucose deprivation#P04397>AMPK#P04639 LEPOC|Ensembl=ENSLOCG00000017182.1|UniProtKB=W5NKS8 W5NKS8 PTHR12933:SF0 ORF PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;binding#GO:0005488 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008146.1|UniProtKB=W5MND1 W5MND1 PTHR15905:SF1 GOLGI-ASSOCIATED KINASE 1B-RELATED GOLGI-ASSOCIATED KINASE 1B LEPOC|Ensembl=ENSLOCG00000012462.1|UniProtKB=W5N3Y3 W5N3Y3 PTHR46216:SF4 PROSAPOSIN RECEPTOR GPR37 FAMILY MEMBER G PROTEIN-COUPLED RECEPTOR 37-LIKE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;positive regulation of MAPK cascade#GO:0043410;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 G-protein coupled receptor#PC00021 Parkinson disease#P00049>Pael-R#P01229 LEPOC|Ensembl=ENSLOCG00000000251.1|UniProtKB=W5LVW8 W5LVW8 PTHR11071:SF596 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004465.1|UniProtKB=W5MAC7 W5MAC7 PTHR20922:SF13 DNL-TYPE ZINC FINGER PROTEIN DNL-TYPE ZINC FINGER PROTEIN protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;localization#GO:0051179;chaperone-mediated protein complex assembly#GO:0051131;protein import into mitochondrial matrix#GO:0030150;biosynthetic process#GO:0009058;mitochondrial protein import pathway#GO:7770058;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein folding#GO:0006457;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;mitochondrial transmembrane transport#GO:1990542;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;intracellular protein transmembrane transport#GO:0065002;cellular component organization or biogenesis#GO:0071840;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015573.1|UniProtKB=W5NEW2 W5NEW2 PTHR35826:SF1 PROTEIN ATP6V1FNB-LIKE PROTEIN SPMIP1 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000001469.1|UniProtKB=W5LZX6 W5LZX6 PTHR23257:SF873 SERINE-THREONINE PROTEIN KINASE MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003759.1|UniProtKB=W5M7X0 W5M7X0 PTHR14021:SF20 IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017800.1|UniProtKB=W5NMP5 W5NMP5 PTHR11711:SF172 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 11 guanyl nucleotide binding#GO:0019001;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000013360.1|UniProtKB=W5N758 W5N758 PTHR12400:SF73 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 1 phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;alcohol biosynthetic process#GO:0046165;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000007319.1|UniProtKB=W5MKF7 W5MKF7 PTHR46037:SF5 PROTEIN ENHANCER OF SEVENLESS 2B SRC-LIKE-ADAPTER protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;growth factor receptor binding#GO:0070851 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;cell communication#GO:0007154 nuclear protein-containing complex#GO:0140513;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cell periphery#GO:0071944;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000001213.1|UniProtKB=W5LZ13 W5LZ13 PTHR24103:SF700 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM7 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005816.1|UniProtKB=W5MF66 W5MF66 PTHR23248:SF40 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007375.1|UniProtKB=W5MKP8 W5MKP8 PTHR21694:SF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 LEPOC|Ensembl=ENSLOCG00000004841.1|UniProtKB=W5MBQ9 W5MBQ9 PTHR24261:SF16 PLASMINOGEN-RELATED PHOSPHOINOSITIDE-3-KINASE-INTERACTING PROTEIN 1 protein binding#GO:0005515;hydrolase activity#GO:0016787;signaling receptor binding#GO:0005102;binding#GO:0005488;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000008733.1|UniProtKB=W5MQG8 W5MQG8 PTHR22882:SF3 SYNPHILIN-1 SYNPHILIN-1 ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488 Parkinson disease#P00049>Synphilin#P01225 LEPOC|Ensembl=ENSLOCG00000002699.1|UniProtKB=W5M465 W5M465 PTHR16079:SF4 UBIQUITIN LIGASE PROTEIN CHFR E3 UBIQUITIN-PROTEIN LIGASE CHFR ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;biological regulation#GO:0065007;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;protein metabolic process#GO:0019538;intracellular signal transduction#GO:0035556 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016004.1|UniProtKB=W5NGF0 W5NGF0 PTHR13354:SF9 ROUND SPERMATID BASIC PROTEIN 1 LYSINE-SPECIFIC DEMETHYLASE RSBN1L histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000004869.1|UniProtKB=W5MBV5 W5MBV5 PTHR28592:SF3 ARMADILLO REPEAT-CONTAINING PROTEIN 1 ARMADILLO REPEAT-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000016148.1|UniProtKB=W5NGY7 W5NGY7 PTHR24073:SF1221 DRAB5-RELATED RAS-RELATED PROTEIN RAB hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;mitochondrion#GO:0005739;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000011905.1|UniProtKB=W5N1Y5 W5N1Y5 PTHR19304:SF8 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 5 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 LEPOC|Ensembl=ENSLOCG00000008676.1|UniProtKB=W5MQ91 W5MQ91 PTHR23504:SF14 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 SOLUTE CARRIER FAMILY 67 MEMBER A2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003503.1|UniProtKB=W5M6Y9 W5M6Y9 PTHR42748:SF7 NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER NMRA-LIKE FAMILY DOMAIN-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000013508.1|UniProtKB=W5N7P7 W5N7P7 PTHR23313:SF0 TSEC1-RELATED TESTIS-EXPRESSED PROTEIN 9 actin binding motor protein#PC00040;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000005401.1|UniProtKB=W5MDQ1 W5MDQ1 PTHR10270:SF204 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-18 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;vasculogenesis#GO:0001570;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;angiogenesis#GO:0001525;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;tube development#GO:0035295;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000016278.1|UniProtKB=W5NHH1 W5NHH1 PTHR24215:SF3 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 2 structural molecule activity#GO:0005198;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;tissue development#GO:0009888;developmental process#GO:0032502;cellular developmental process#GO:0048869 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;I band#GO:0031674;sarcomere#GO:0030017;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000009223.1|UniProtKB=W5MS96 W5MS96 PTHR10554:SF11 SYNTROPHIN BETA-1-SYNTROPHIN cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006510.1|UniProtKB=W5MHK4 W5MHK4 PTHR14540:SF2 INTEGRATOR COMPLEX SUBUNIT 15 INTEGRATOR COMPLEX SUBUNIT 15 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;integrator complex#GO:0032039;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000015853.1|UniProtKB=W5NFW0 W5NFW0 PTHR14513:SF0 PROTECTION OF TELOMERES 1 PROTECTION OF TELOMERES PROTEIN 1 molecular function regulator activity#GO:0098772;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;DNA binding#GO:0003677;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697 telomere organization#GO:0032200;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;regulation of telomere maintenance#GO:0032204;organelle organization#GO:0006996;telomere capping#GO:0016233;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of telomere maintenance via telomere lengthening#GO:1904356;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007 chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;nuclear telomere cap complex#GO:0000783;nucleus#GO:0005634;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000015902.1|UniProtKB=W5NG23 W5NG23 PTHR23236:SF25 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H RNA-BINDING PROTEIN 34 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000003069.1|UniProtKB=W5M5F2 W5M5F2 PTHR15215:SF2 CABIT DOMAIN-CONTAINING PROTEIN PROTEIN THEMIS2 immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of immune response#GO:0050776;immune system process#GO:0002376;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;immune response-activating signaling pathway#GO:0002757 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015685.1|UniProtKB=W5NFA5 W5NFA5 PTHR45850:SF5 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-5 cytoskeletal protein binding#GO:0008092;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;protein binding#GO:0005515 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012920.1|UniProtKB=W5N5K0 W5N5K0 PTHR24410:SF18 HL07962P-RELATED BTB DOMAIN CONTAINING 1 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004092.1|UniProtKB=W5M925 W5M925 PTHR10075:SF143 BASIGIN RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017614.1|UniProtKB=W5NM60 W5NM60 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183-LIKE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009427.1|UniProtKB=W5MSZ4 W5MSZ4 PTHR31935:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cilium organization#GO:0044782;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;non-motile cilium assembly#GO:1905515;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cytoplasmic microtubule organization#GO:0031122;cell projection organization#GO:0030030 LEPOC|Ensembl=ENSLOCG00000017221.1|UniProtKB=W5NKY7 W5NKY7 PTHR45972:SF3 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 11 LEPOC|Ensembl=ENSLOCG00000013445.1|UniProtKB=W5N7G9 W5N7G9 PTHR10792:SF8 60S RIBOSOMAL PROTEIN L24 RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000001094.1|UniProtKB=W5LYS5 W5LYS5 PTHR10201:SF336 MATRIX METALLOPROTEINASE COLLAGENASE 3 metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000016838.1|UniProtKB=W5NJK1 W5NJK1 PTHR23409:SF20 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 biosynthetic process#GO:0009058;cellular process#GO:0009987;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;reductase#PC00198 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909;p53 pathway#P00059>R2#G04692;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915 LEPOC|Ensembl=ENSLOCG00000005280.1|UniProtKB=W5MDA2 W5MDA2 PTHR15838:SF1 NUCLEOLAR PROTEIN OF 40 KDA ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 17 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;RNA stabilization#GO:0043489;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 LEPOC|Ensembl=ENSLOCG00000012268.1|UniProtKB=W5N387 W5N387 PTHR48482:SF3 INTERLEUKIN-19-RELATED INTERLEUKIN-19 receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016553.1|UniProtKB=W5NII3 W5NII3 TULP3 PTHR16517:SF20 TUBBY-RELATED TUBBY PROTEIN HOMOLOG protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036 cilium#GO:0005929;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004682.1|UniProtKB=W5MB58 W5MB58 PTHR10943:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;proteasome complex#GO:0000502;cytoplasm#GO:0005737;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000005860.1|UniProtKB=W5MFC1 W5MFC1 PTHR18945:SF61 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT DELTA channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594 response to nitrogen compound#GO:1901698;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;neuromuscular process#GO:0050905;trans-synaptic signaling#GO:0099537;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;system process#GO:0003008;establishment of localization#GO:0051234;muscle contraction#GO:0006936;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;multicellular organismal process#GO:0032501;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;nervous system process#GO:0050877;cellular response to chemical stimulus#GO:0070887;skeletal muscle contraction#GO:0003009;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;muscle system process#GO:0003012;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536 postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>delta#P01092;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000003661.1|UniProtKB=W5M7I6 W5M7I6 PTHR46311:SF1 CALCIUM-BINDING PROTEIN 8-RELATED CALCIUM-BINDING PROTEIN 7 Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 LEPOC|Ensembl=ENSLOCG00000004080.1|UniProtKB=W5M952 W5M952 PTHR24092:SF98 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IB ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303 cellular component organization#GO:0016043;cell differentiation#GO:0030154;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cell development#GO:0048468;lipid localization#GO:0010876;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological quality#GO:0065008;neuron development#GO:0048666;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;nervous system development#GO:0007399;developmental process#GO:0032502;neuron differentiation#GO:0030182;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;regulation of membrane lipid distribution#GO:0097035;neurogenesis#GO:0022008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018355.1|UniProtKB=W5NP97 W5NP97 PTHR22639:SF13 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3-LIKE viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000003682.1|UniProtKB=W5M7L5 W5M7L5 PTHR12247:SF86 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004291.1|UniProtKB=W5M9R6 W5M9R6 PTHR16070:SF2 PROTEIN FAM222A-RELATED PROTEIN FAM222A LEPOC|Ensembl=ENSLOCG00000014752.1|UniProtKB=W5NC09 W5NC09 PTHR24056:SF171 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 20 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009341.1|UniProtKB=W5MSN6 W5MSN6 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011358.1|UniProtKB=W5N009 W5N009 PTHR10901:SF8 TROPOMODULIN TROPOMODULIN-1 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 actin filament organization#GO:0007015;system process#GO:0003008;cellular developmental process#GO:0048869;muscle contraction#GO:0006936;developmental process#GO:0032502;multicellular organismal process#GO:0032501;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 actin cytoskeleton#GO:0015629;contractile muscle fiber#GO:0043292;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000011867.1|UniProtKB=W5N1T9 W5N1T9 PTHR48012:SF19 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 5 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCK#P00268;Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861 LEPOC|Ensembl=ENSLOCG00000006765.1|UniProtKB=W5MII5 W5MII5 WIZ PTHR24396:SF22 ZINC FINGER PROTEIN PROTEIN WIZ DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002198.1|UniProtKB=W5M2F4 W5M2F4 PTHR24054:SF16 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA-RELATED catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to stress#GO:0033554;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974 intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459 LEPOC|Ensembl=ENSLOCG00000016798.1|UniProtKB=W5NJF4 W5NJF4 PTHR10426:SF130 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 LEPOC|Ensembl=ENSLOCG00000011804.1|UniProtKB=W5N1K7 W5N1K7 PTHR11592:SF143 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to oxidative stress#GO:0034599;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000003994.1|UniProtKB=W5M8Q8 W5M8Q8 PTHR45817:SF10 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE-LIKE 5B ISOFORM X1 oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;extracellular structure organization#GO:0043062;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;collagen fibril organization#GO:0030199;enzyme-linked receptor protein signaling pathway#GO:0007167;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016736.1|UniProtKB=W5NJ73 W5NJ73 PTHR13007:SF19 PRE-MRNA SPLICING FACTOR-RELATED PRE-MRNA-SPLICING FACTOR 18 ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000015637.1|UniProtKB=W5NF49 W5NF49 PTHR10183:SF322 CALPAIN CALPAIN-11 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000003438.1|UniProtKB=W5M6R4 W5M6R4 PTHR11318:SF4 GUANYLIN FAMILY MEMBER GUANYLATE CYCLASE ACTIVATOR 2B molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;cyclase regulator activity#GO:0010851;enzyme activator activity#GO:0008047 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003603.1|UniProtKB=W5M7B2 W5M7B2 PTHR45702:SF1 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER ADAM10 ENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;membrane protein ectodomain proteolysis#GO:0006509;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;protein metabolic process#GO:0019538;cell communication#GO:0007154;proteolysis#GO:0006508;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006044.1|UniProtKB=W5MFZ0 W5MFZ0 PTHR21435:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 cellular localization#GO:0051641;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization#GO:0016043;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;mitochondrion organization#GO:0007005;protein insertion into mitochondrial inner membrane#GO:0045039;membrane organization#GO:0061024;mitochondrial protein import pathway#GO:7770058;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996 TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743 LEPOC|Ensembl=ENSLOCG00000008457.1|UniProtKB=W5MPI5 W5MPI5 PTHR23081:SF36 RNA POLYMERASE II CTD PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Transcription regulation by bZIP transcription factor#P00055>TFIIF#P01394;General transcription regulation#P00023>TFIIF#P00665 LEPOC|Ensembl=ENSLOCG00000015536.1|UniProtKB=W5NER4 W5NER4 PTHR10026:SF70 CYCLIN CYCLIN-Q cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000007170.1|UniProtKB=W5MJW7 W5MJW7 PTHR11952:SF4 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLHEXOSAMINE PYROPHOSPHORYLASE transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;UDP-N-acetylglucosamine biosynthetic process#GO:0006048 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000005117.1|UniProtKB=W5MCQ0 W5MCQ0 PTHR15240:SF1 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 2 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;caveola#GO:0005901;membrane raft#GO:0045121;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007018.1|UniProtKB=W5MJD4 W5MJD4 PTHR11633:SF4 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR D protein binding#GO:0005515;growth factor receptor binding#GO:0070851;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;positive regulation of MAPK cascade#GO:0043410;positive regulation of locomotion#GO:0040017;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224 LEPOC|Ensembl=ENSLOCG00000018252.1|UniProtKB=W5NNZ4 W5NNZ4 PTHR47266:SF40 ENDONUCLEASE-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012325.1|UniProtKB=W5N3F6 W5N3F6 PTHR23323:SF29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;cellular component organization#GO:0016043;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;lytic vacuole organization#GO:0080171;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;endosome organization#GO:0007032;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome organization#GO:0007040;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle tethering complex#GO:0099023 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014637.1|UniProtKB=W5NBK7 W5NBK7 PTHR10024:SF351 SYNAPTOTAGMIN C2 DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;molecular sensor activity#GO:0140299;protein binding#GO:0005515;SNARE binding#GO:0000149;phospholipid binding#GO:0005543;binding#GO:0005488 transport#GO:0006810;establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;synaptic signaling#GO:0099536;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000006218.1|UniProtKB=W5MGJ8 W5MGJ8 PTHR45889:SF2 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 1 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;detection of stimulus#GO:0051606;homophilic cell-cell adhesion#GO:0007156;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of natural killer cell mediated immunity#GO:0002715;regulation of leukocyte mediated immunity#GO:0002703;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910;cell recognition#GO:0008037;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of response to external stimulus#GO:0032101;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of response to external stimulus#GO:0032103;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of lymphocyte mediated immunity#GO:0002706;regulation of cell killing#GO:0031341;cell adhesion#GO:0007155 cell junction#GO:0030054;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000002190.1|UniProtKB=W5M2E1 W5M2E1 PTHR13328:SF7 NEGATIVE ELONGATION FACTOR A NELF-A NEGATIVE ELONGATION FACTOR A regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000007622.1|UniProtKB=W5MLI8 W5MLI8 PTHR24020:SF77 COLLAGEN ALPHA VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 1 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000001430.1|UniProtKB=W5LZS7 W5LZS7 PTHR46170:SF1 GATOR COMPLEX PROTEIN WDR59 GATOR2 COMPLEX PROTEIN WDR59 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;regulation of TORC1 signaling#GO:1903432;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular response to amino acid starvation#GO:0034198;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to nutrient levels#GO:0031667;positive regulation of TORC1 signaling#GO:1904263;response to stress#GO:0006950 membrane#GO:0016020;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;Seh1-associated complex#GO:0035859;vacuolar membrane#GO:0005774 LEPOC|Ensembl=ENSLOCG00000003721.1|UniProtKB=W5M7R3 W5M7R3 IL12A PTHR48485:SF1 INTERLEUKIN-12 SUBUNIT BETA-RELATED INTERLEUKIN-12 SUBUNIT ALPHA signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 LEPOC|Ensembl=ENSLOCG00000012174.1|UniProtKB=W5N2W1 W5N2W1 PTHR11984:SF32 CONNEXIN GAP JUNCTION DELTA-2 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 cell communication#GO:0007154;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;regulation of biological process#GO:0050789 cell junction#GO:0030054;anchoring junction#GO:0070161;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000016034.1|UniProtKB=W5NGJ7 W5NGJ7 PTHR10824:SF36 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COA THIOESTERASE 14 PRECURSOR-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;fatty acyl-CoA hydrolase activity#GO:0047617;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824 purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000000564.1|UniProtKB=W5LWW4 W5LWW4 PTHR23266:SF420 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;binding#GO:0005488 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007828.1|UniProtKB=W5MMC5 W5MMC5 PTHR23140:SF10 RNA PROCESSING PROTEIN LD23810P U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000012043.1|UniProtKB=W5N2G0 W5N2G0 PTHR13680:SF33 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 2 transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transaminase activity#GO:0008483;iron-sulfur cluster binding#GO:0051536 autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;autophagy#GO:0006914;inorganic ion homeostasis#GO:0098771;process utilizing autophagic mechanism#GO:0061919;intracellular monoatomic ion homeostasis#GO:0006873;intracellular iron ion homeostasis#GO:0006879;catabolic process#GO:0009056;homeostatic process#GO:0042592 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000015747.1|UniProtKB=W5NFH6 W5NFH6 PTHR14911:SF1 THUMP DOMAIN-CONTAINING U6 SNRNA (GUANINE-N(2))-METHYLTRANSFERASE THUMPD2 catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016955.1|UniProtKB=W5NK01 W5NK01 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000046.1|UniProtKB=W5LV97 W5LV97 PTHR24055:SF561 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 7 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Parkinson disease#P00049>ERK#P01211;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;CCKR signaling map#P06959>MAPK7#P07021;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Interleukin signaling pathway#P00036>ERK#P00965;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Endothelin signaling pathway#P00019>ERK#P00566;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Apoptosis signaling pathway#P00006>MAPK#P00269;FGF signaling pathway#P00021>ERK1-2#P00627;PDGF signaling pathway#P00047>ERK#P01143 LEPOC|Ensembl=ENSLOCG00000016371.1|UniProtKB=W5NHV4 W5NHV4 PTHR10390:SF61 HOMEOBOX PROTEIN SIX HOMEOBOX DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008529.1|UniProtKB=W5MPR6 W5MPR6 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004317.1|UniProtKB=W5M9U5 W5M9U5 PTHR21737:SF21 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 MARVEL DOMAIN CONTAINING 3 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003215.1|UniProtKB=W5M5Z7 W5M5Z7 PTHR11800:SF2 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098 gene expression#GO:0010467;DNA-templated transcription#GO:0006351;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;transcription by RNA polymerase II#GO:0006366 intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 LEPOC|Ensembl=ENSLOCG00000015067.1|UniProtKB=W5ND38 W5ND38 PTHR10373:SF25 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;Wnt signaling pathway#GO:0016055;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;chromosome#GO:0005694 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>TCF#P01437;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Gonadotropin-releasing hormone receptor pathway#P06664>TCF#P06701;Cadherin signaling pathway#P00012>TCF/LEF#P00465 LEPOC|Ensembl=ENSLOCG00000015432.1|UniProtKB=W5NED1 W5NED1 PTHR34253:SF1 PROTEIN LLP HOMOLOG PROTEIN LLP HOMOLOG generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;neuron projection extension#GO:1990138;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;developmental cell growth#GO:0048588;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;developmental growth#GO:0048589;cellular developmental process#GO:0048869;cell growth#GO:0016049;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010093.1|UniProtKB=W5MVE0 W5MVE0 SIX4 PTHR10390:SF64 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX4A-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000007646.1|UniProtKB=W5MLN1 W5MLN1 PTHR11347:SF102 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC PHOSPHODIESTERASE PDE-2-RELATED hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;identical protein binding#GO:0042802;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515 negative regulation of response to stimulus#GO:0048585;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;nucleotide catabolic process#GO:0009166;cyclic nucleotide metabolic process#GO:0009187;regulation of response to stimulus#GO:0048583;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nucleoside phosphate catabolic process#GO:1901292;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;regulation of mitochondrion organization#GO:0010821;purine ribonucleotide catabolic process#GO:0009154;organophosphate catabolic process#GO:0046434;positive regulation of biosynthetic process#GO:0009891;purine nucleotide catabolic process#GO:0006195;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;small molecule metabolic process#GO:0044281;regulation of cellular component organization#GO:0051128;negative regulation of biological process#GO:0048519;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;regulation of organelle organization#GO:0033043;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;ribonucleotide metabolic process#GO:0009259;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;cell periphery#GO:0071944;mitochondrial inner membrane#GO:0005743;cytosol#GO:0005829;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;organelle outer membrane#GO:0031968;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;outer membrane#GO:0019867;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;organelle inner membrane#GO:0019866;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;synaptic membrane#GO:0097060;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000013956.1|UniProtKB=W5N993 W5N993 PTHR12276:SF16 EPSIN/ENT-RELATED EPSIN-3 lipid binding#GO:0008289;protein binding#GO:0005515;phospholipid binding#GO:0005543;binding#GO:0005488;clathrin binding#GO:0030276 receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008512.1|UniProtKB=W5MPQ0 W5MPQ0 PTHR11103:SF10 SLR1189 PROTEIN HOMOCYSTEINE S-METHYLTRANSFERASE 1-RELATED Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024;Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953 LEPOC|Ensembl=ENSLOCG00000012981.1|UniProtKB=W5N5T2 W5N5T2 PTHR12663:SF2 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED SISTER CHROMATID COHESION PROTEIN PDS5 HOMOLOG A chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016369.1|UniProtKB=W5NHW0 W5NHW0 PTHR11119:SF86 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 1 ISOFORM X1 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016675.1|UniProtKB=W5NIZ2 W5NIZ2 PTHR23123:SF15 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 7A catalytic activity#GO:0003824;histone demethylase activity#GO:0032452;protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;histone modifying activity#GO:0140993 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000005033.1|UniProtKB=W5MCF2 W5MCF2 PTHR20914:SF24 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 LYMPHOCYTE ANTIGEN 6 FAMILY MEMBER M2-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003681.1|UniProtKB=W5M7K9 W5M7K9 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 sensory system development#GO:0048880;multicellular organismal process#GO:0032501;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004969.1|UniProtKB=W5MC69 W5MC69 PTHR15031:SF7 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 2 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017259.1|UniProtKB=W5NL38 W5NL38 PTHR10174:SF73 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CLAVESIN-2 binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 lysosome organization#GO:0007040;lytic vacuole organization#GO:0080171;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840 Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000013612.1|UniProtKB=W5N822 W5N822 PTHR11371:SF26 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE nuclease activity#GO:0004518;DNA binding#GO:0003677;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676;binding#GO:0005488;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640 nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000009202.1|UniProtKB=W5MS68 W5MS68 PTHR10182:SF9 CALCIUM-BINDING PROTEIN 39-RELATED CALCIUM-BINDING PROTEIN 39-LIKE protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 LEPOC|Ensembl=ENSLOCG00000000816.1|UniProtKB=W5LXS9 W5LXS9 PTHR10379:SF13 MTG8 ETO EIGHT TWENTY ONE PROTEIN PROTEIN CBFA2T2 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000008089.1|UniProtKB=W5MN62 W5MN62 PTHR24340:SF37 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN SLOU sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000012753.1|UniProtKB=W5N4Y8 W5N4Y8 PTHR23055:SF65 CALCIUM BINDING PROTEINS A-TYPE POTASSIUM CHANNEL MODULATORY PROTEIN KCNIP2 channel regulator activity#GO:0016247;cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000003705.1|UniProtKB=W5M7P9 W5M7P9 PTHR12534:SF0 30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR SMALL RIBOSOMAL SUBUNIT PROTEIN US2M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000005929.1|UniProtKB=W5MFP4 W5MFP4 PTHR11915:SF422 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1 actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;membrane#GO:0016020;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000010173.1|UniProtKB=W5MVP5 W5MVP5 PTHR18901:SF48 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE-5'-PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004811.1|UniProtKB=W5MBL7 W5MBL7 PTHR11945:SF145 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2A enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;histone deacetylase binding#GO:0042826;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;heart development#GO:0007507;animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;Oxidative stress response#P00046>MEF-2#P01128 LEPOC|Ensembl=ENSLOCG00000005747.1|UniProtKB=W5MEY0 W5MEY0 PTHR12487:SF5 TEASHIRT-RELATED TEASHIRT HOMOLOG 3 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nervous system process#GO:0050877;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of system process#GO:0044057;regulation of biosynthetic process#GO:0009889;system process#GO:0003008;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000004948.1|UniProtKB=W5MC43 W5MC43 PTHR10174:SF225 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN heterocyclic compound binding#GO:1901363;transporter activity#GO:0005215;lipid transfer activity#GO:0120013;phosphatidylinositol bisphosphate binding#GO:1902936;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 localization#GO:0051179;establishment of localization#GO:0051234;vitamin transport#GO:0051180;vitamin E metabolic process#GO:0042360;metabolic process#GO:0008152;transport#GO:0006810;cellular process#GO:0009987 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;late endosome#GO:0005770;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000012642.1|UniProtKB=W5N4K8 W5N4K8 PTHR15036:SF88 PIKACHURIN-LIKE PROTEIN PIKACHURIN cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731 cell periphery#GO:0071944;basement membrane#GO:0005604;extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell junction#GO:0030054 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015243.1|UniProtKB=W5NDP7 W5NDP7 PTHR24394:SF58 ZINC FINGER PROTEIN TRANSCRIPTIONAL REGULATOR KAISO DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003521.1|UniProtKB=W5M711 W5M711 PTHR12869:SF0 SMALL SEVEN TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN BOS COMPLEX SUBUNIT TMEM147 LEPOC|Ensembl=ENSLOCG00000015694.1|UniProtKB=W5NFB4 W5NFB4 PTHR13096:SF8 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 1 histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;protein demethylase activity#GO:0140457 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004203.1|UniProtKB=W5M9G7 W5M9G7 PTHR24115:SF549 KINESIN-RELATED KINESIN-LIKE PROTEIN ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000011782.1|UniProtKB=W5N1I0 W5N1I0 PTHR45652:SF18 GLIAL FIBRILLARY ACIDIC PROTEIN ALPHA-INTERNEXIN structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;postsynapse#GO:0098794;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010535.1|UniProtKB=W5MWZ7 W5MWZ7 PTHR47978:SF26 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33B catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 macroautophagy#GO:0016236;biological regulation#GO:0065007;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular component organization#GO:0016043;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;regulation of secretion#GO:0051046;organelle assembly#GO:0070925 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endosome#GO:0005768 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000001769.1|UniProtKB=W5M0Z6 W5M0Z6 PTHR46792:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 80 COILED-COIL DOMAIN-CONTAINING PROTEIN 80 positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;cellular process#GO:0009987;cellular component organization#GO:0016043;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007489.1|UniProtKB=W5ML34 W5ML34 PTHR22765:SF345 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING FINGER PROTEIN 215 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009232.1|UniProtKB=W5MS99 W5MS99 PTHR11551:SF5 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 2 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014768.1|UniProtKB=W5NC25 W5NC25 PTHR21640:SF1 FAMILY NOT NAMED NESPRIN-4 LEPOC|Ensembl=ENSLOCG00000003825.1|UniProtKB=W5M856 W5M856 PTHR23037:SF7 CYTOKINE RECEPTOR INTERLEUKIN-21 RECEPTOR immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016770.1|UniProtKB=W5NJB9 W5NJB9 PTHR21580:SF65 SHIPPO-1-RELATED BOREALIN N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285;cellular process#GO:0009987;sperm motility#GO:0097722;cilium movement involved in cell motility#GO:0060294;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016434.1|UniProtKB=W5NI39 W5NI39 PTHR24166:SF30 ROLLING PEBBLES, ISOFORM B ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 63 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016130.1|UniProtKB=W5NGX0 W5NGX0 PTHR10682:SF6 POLY A POLYMERASE POLY(A) POLYMERASE GAMMA transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000761.1|UniProtKB=W5LXI6 W5LXI6 PTHR25466:SF11 T-LYMPHOCYTE ACTIVATION ANTIGEN GALECTIN 17-RELATED signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011715.1|UniProtKB=W5N190 W5N190 PTHR10903:SF180 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7-LIKE ISOFORM X1 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017634.1|UniProtKB=W5NM80 W5NM80 PTHR24156:SF7 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 34B LEPOC|Ensembl=ENSLOCG00000011393.1|UniProtKB=W5N046 W5N046 PTHR45752:SF153 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017917.1|UniProtKB=W5NN11 W5NN11 PTHR11537:SF281 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 6 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;action potential#GO:0001508;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016240.1|UniProtKB=W5NHB4 W5NHB4 PTHR12232:SF4 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004154.1|UniProtKB=W5M9B0 W5M9B0 PTHR12247:SF130 POLYCOMB GROUP PROTEIN L3MBTL HISTONE METHYL-LYSINE BINDING PROTEIN 4 protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010262.1|UniProtKB=W5MW00 W5MW00 PTHR46253:SF3 TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 3 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 LEPOC|Ensembl=ENSLOCG00000003723.1|UniProtKB=W5M7R6 W5M7R6 PTHR23107:SF21 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN CALCIUM-RESPONSIVE TRANSACTIVATOR transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;positive regulation of cell projection organization#GO:0031346;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;regulation of dendrite morphogenesis#GO:0048814;regulation of neurogenesis#GO:0050767;regulation of gene expression#GO:0010468;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biosynthetic process#GO:0009889;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of cell differentiation#GO:0045597;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000002125.1|UniProtKB=W5M293 W5M293 PTHR18934:SF274 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT DNA_RNA HELICASE DHX36 binding#GO:0005488;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;DNA helicase activity#GO:0003678;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;RNA binding#GO:0003723;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000002036.1|UniProtKB=W5M1V7 W5M1V7 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017347.1|UniProtKB=W5NLE3 W5NLE3 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010609.1|UniProtKB=W5MX92 W5MX92 PTHR15454:SF35 NISCHARIN RELATED NISCHARIN cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;Rac protein signal transduction#GO:0016601;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015001.1|UniProtKB=W5NCW1 W5NCW1 PTHR15813:SF8 SORTING NEXIN-22 AND 24 SORTING NEXIN-22 phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013853.1|UniProtKB=W5N8X7 W5N8X7 PTHR24103:SF706 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM39 ISOFORM X1-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005074.1|UniProtKB=W5MCK5 W5MCK5 PTHR11267:SF82 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000015929.1|UniProtKB=W5NG53 W5NG53 PTHR47972:SF65 KINESIN-LIKE PROTEIN KLP-3 KINESIN-LIKE PROTEIN KIFC3 ISOFORM X1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 microtubule-based process#GO:0007017;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000017963.1|UniProtKB=W5NN57 W5NN57 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000012924.1|UniProtKB=W5N5K8 W5N5K8 PTHR14206:SF3 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BAR_IMD DOMAIN-CONTAINING ADAPTER PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;actin filament bundle assembly#GO:0051017;regulation of supramolecular fiber organization#GO:1902903;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;actin filament bundle organization#GO:0061572;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006561.1|UniProtKB=W5MHV0 W5MHV0 PTHR23317:SF78 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 7 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;regulation of Rho protein signal transduction#GO:0035023;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of response to stimulus#GO:0048583;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;system development#GO:0048731;anatomical structure development#GO:0048856 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000013244.1|UniProtKB=W5N6Q5 W5N6Q5 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000017681.1|UniProtKB=W5NMC7 W5NMC7 PTHR24156:SF4 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 34A LEPOC|Ensembl=ENSLOCG00000004541.1|UniProtKB=W5MAM1 W5MAM1 PTHR22880:SF246 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 3 histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012885.1|UniProtKB=W5N5G1 W5N5G1 PTHR45721:SF16 LAMIN DM0-RELATED LAMIN-L(III) structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;establishment of organelle localization#GO:0051656;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular localization#GO:0051641;membrane organization#GO:0061024;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;protein localization to nucleus#GO:0034504;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;establishment of localization#GO:0051234;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;transport#GO:0006810;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;nuclear migration#GO:0007097;heterochromatin formation#GO:0031507;localization#GO:0051179;organelle localization#GO:0051640;localization within membrane#GO:0051668 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 FAS signaling pathway#P00020>Nuclear Lamin#P00616 LEPOC|Ensembl=ENSLOCG00000012328.1|UniProtKB=W5N3G7 W5N3G7 PTHR21682:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 LEPOC|Ensembl=ENSLOCG00000006767.1|UniProtKB=W5MIH2 W5MIH2 PTHR12431:SF19 SORTING NEXIN 17 AND 27 SORTING NEXIN-27 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;macromolecule metabolic process#GO:0043170;transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907;metabolic process#GO:0008152 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012628.1|UniProtKB=W5N4J2 W5N4J2 PTHR13369:SF0 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017740.1|UniProtKB=W5NMI5 W5NMI5 PTHR11829:SF405 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D3 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000007593.1|UniProtKB=W5MLF3 W5MLF3 PTHR17920:SF3 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000002590.1|UniProtKB=W5M3U4 W5M3U4 PTHR24300:SF319 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 1 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010547.1|UniProtKB=W5MX15 W5MX15 PTHR32343:SF71 SERINE/ARGININE-RICH SPLICING FACTOR SPLICING REGULATORY GLUTAMINE_LYSINE-RICH PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000004958.1|UniProtKB=W5MC72 W5MC72 PTHR18952:SF134 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 15 catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003623.1|UniProtKB=W5M7D8 W5M7D8 PTHR35268:SF1 PROTEIN CCSMST1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 4 cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex III assembly#GO:0034551;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000007757.1|UniProtKB=W5MM17 W5MM17 PTHR13903:SF33 PIRIN-RELATED PIRIN transcription regulator activity#GO:0140110;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 mononuclear cell differentiation#GO:1903131;cellular process#GO:0009987;leukocyte differentiation#GO:0002521;hemopoiesis#GO:0030097;cell development#GO:0048468;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000010836.1|UniProtKB=W5MY23 W5MY23 PTHR11929:SF194 ALPHA- 1,3 -FUCOSYLTRANSFERASE GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 3 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000016992.1|UniProtKB=W5NK46 W5NK46 PTHR12728:SF0 BRIX DOMAIN CONTAINING PROTEIN RIBOSOME PRODUCTION FACTOR 2 HOMOLOG rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000013798.1|UniProtKB=W5N8Q2 W5N8Q2 PTHR12884:SF0 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000007811.1|UniProtKB=W5MM87 W5MM87 PTHR10901:SF9 TROPOMODULIN TROPOMODULIN-4 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;developmental process#GO:0032502;muscle contraction#GO:0006936;actin filament organization#GO:0007015;system process#GO:0003008;cellular developmental process#GO:0048869 contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000014787.1|UniProtKB=W5NC51 W5NC51 PTHR10502:SF245 ANNEXIN ANNEXIN phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;nucleus#GO:0005634 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000017602.1|UniProtKB=W5NM48 W5NM48 PTHR24230:SF128 G-PROTEIN COUPLED RECEPTOR BLT1-LIKE1 PROTEIN-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;neuropeptide signaling pathway#GO:0007218 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012550.1|UniProtKB=W5N497 W5N497 PTHR10218:SF231 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE BINDING PROTEIN (G PROTEIN) ALPHA V1 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020;heterotrimeric G-protein#PC00117 LEPOC|Ensembl=ENSLOCG00000003406.1|UniProtKB=W5M6M7 W5M6M7 PTHR24377:SF1040 IP01015P-RELATED ZINC FINGER PROTEIN 467 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000000528.1|UniProtKB=W5LWS5 W5LWS5 PTHR16675:SF191 MHC CLASS I-RELATED CLASS I HISTOCOMPATIBILITY ANTIGEN, GOGO-C*0202 ALPHA CHAIN-LIKE-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000000575.1|UniProtKB=W5LWX9 W5LWX9 PTHR31046:SF4 TRANSMEMBRANE PROTEIN 121 TRANSMEMBRANE PROTEIN 121 ISOFORM X2 LEPOC|Ensembl=ENSLOCG00000012640.1|UniProtKB=W5N4J9 W5N4J9 PTHR13182:SF8 ZINC FINGER PROTEIN 622 CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622 binding#GO:0005488;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006376.1|UniProtKB=W5MH38 W5MH38 PTHR19871:SF29 BETA TRANSDUCIN-RELATED PROTEIN NACHT AND WD REPEAT DOMAIN-CONTAINING PROTEIN 2-LIKE LEPOC|Ensembl=ENSLOCG00000013584.1|UniProtKB=W5N801 W5N801 PTHR23239:SF180 INTERMEDIATE FILAMENT KERATIN 96-RELATED structural molecule activity#GO:0005198 anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;epithelium development#GO:0060429;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009 intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000009754.1|UniProtKB=W5MU58 W5MU58 PTHR16222:SF34 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLGLYCOHYDROLASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003904.1|UniProtKB=W5M8F7 W5M8F7 PTHR13076:SF5 COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1B DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005686.1|UniProtKB=W5MEQ7 W5MEQ7 PTHR10655:SF22 LYSOPHOSPHOLIPASE-RELATED ACYL-PROTEIN THIOESTERASE 1 catalytic activity, acting on a protein#GO:0140096;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;thiolester hydrolase activity#GO:0016790;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;regulation of vesicle-mediated transport#GO:0060627;negative regulation of transport#GO:0051051;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of establishment of protein localization#GO:0070201;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of transport#GO:0051049 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lipase#PC00143;phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000014085.1|UniProtKB=W5N9P8 W5N9P8 PTHR31733:SF1 RIBONUCLEASE KAPPA RIBONUCLEASE KAPPA transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;ATPase complex#GO:1904949 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000009715.1|UniProtKB=W5MU11 W5MU11 PTHR10113:SF10 PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051;RNA binding#GO:0003723 translational termination#GO:0006415;translation#GO:0006412;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein-containing complex disassembly#GO:0032984;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation factor#PC00223;translation release factor#PC00225 LEPOC|Ensembl=ENSLOCG00000001502.1|UniProtKB=W5M012 W5M012 PTHR22917:SF1 HEMOPEXIN DOMAIN-CONTAINING PROTEIN PROTEOGLYCAN 4 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000007839.1|UniProtKB=W5MMB6 W5MMB6 PTHR11905:SF130 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 15 protein binding#GO:0005515;hydrolase activity#GO:0016787;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;binding#GO:0005488;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;integrin binding#GO:0005178;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;cell adhesion molecule binding#GO:0050839 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;primary metabolic process#GO:0044238;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;proteolysis#GO:0006508;immune system process#GO:0002376;protein metabolic process#GO:0019538;cell communication#GO:0007154;cellular process#GO:0009987;immune response#GO:0006955;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000000042.1|UniProtKB=W5LV93 W5LV93 PTHR24253:SF144 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005702.1|UniProtKB=W5MES2 W5MES2 PTHR46203:SF1 PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65 MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 translation release factor#PC00225 LEPOC|Ensembl=ENSLOCG00000015719.1|UniProtKB=W5NFE0 W5NFE0 PTHR31553:SF2 NF-KAPPA-B ESSENTIAL MODULATOR OPTINEURIN protein binding#GO:0005515;modification-dependent protein binding#GO:0140030;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;localization#GO:0051179;cellular component organization#GO:0016043;Golgi organization#GO:0007030;regulation of biological process#GO:0050789;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;protein localization to Golgi apparatus#GO:0034067;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;endomembrane system organization#GO:0010256;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 Huntington disease#P00029>FIP-2#P00772 LEPOC|Ensembl=ENSLOCG00000017564.1|UniProtKB=W5NM10 W5NM10 PTHR15344:SF2 CDC42 EFFECTOR PROTEIN BORG ZGC:154093 binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;protein binding#GO:0005515 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cell projection assembly#GO:0060491;positive regulation of cell projection organization#GO:0031346;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of supramolecular fiber organization#GO:1902903;cellular response to stimulus#GO:0051716;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;small GTPase-mediated signal transduction#GO:0007264;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;positive regulation of organelle organization#GO:0010638;Rho protein signal transduction#GO:0007266;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;regulation of anatomical structure size#GO:0090066;positive regulation of cellular component biogenesis#GO:0044089;intracellular signaling cassette#GO:0141124;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011311.1|UniProtKB=W5MZU4 W5MZU4 PTHR19143:SF444 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-3 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012958.1|UniProtKB=W5N5Q1 W5N5Q1 PTHR10269:SF3 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;nervous system development#GO:0007399;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013468.1|UniProtKB=W5N7K4 W5N7K4 PTHR46116:SF51 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009707.1|UniProtKB=W5MU02 W5MU02 PTHR12245:SF7 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN F-BOX_SPRY DOMAIN-CONTAINING PROTEIN 1 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;synapse assembly#GO:0007416;catabolic process#GO:0009056;developmental process#GO:0032502;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;proteasomal protein catabolic process#GO:0010498;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607 synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;cell junction#GO:0030054;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013879.1|UniProtKB=W5N908 W5N908 PTHR19965:SF35 RNA AND EXPORT FACTOR BINDING PROTEIN THO COMPLEX SUBUNIT 4 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;gene expression#GO:0010467 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007318.1|UniProtKB=W5MKF6 W5MKF6 PTHR11673:SF13 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-2 translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000009794.1|UniProtKB=W5MUB2 W5MUB2 PTHR24278:SF35 COAGULATION FACTOR PROTEIN Z, VITAMIN K-DEPENDENT PLASMA GLYCOPROTEIN B hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000009423.1|UniProtKB=W5MSZ1 W5MSZ1 PTHR15427:SF28 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010277.1|UniProtKB=W5MW24 W5MW24 PTHR13143:SF6 TETRATRICOPEPTIDE REPEAT PROTEIN 19 TETRATRICOPEPTIDE REPEAT PROTEIN 19, MITOCHONDRIAL cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001840.1|UniProtKB=W5M182 W5M182 PEMT PTHR15458:SF5 PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-methyltransferase activity#GO:0008170 glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;phosphatidylcholine biosynthetic process#GO:0006656;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000003717.1|UniProtKB=W5M7R9 W5M7R9 PTHR46054:SF1 MATERNAL EFFECT PROTEIN STAUFEN DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 2 double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;gamete generation#GO:0007276;RNA localization#GO:0006403;microtubule-based movement#GO:0007018;cell differentiation#GO:0030154;cell development#GO:0048468;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;protein localization to cell junction#GO:1902414;sexual reproduction#GO:0019953;microtubule-based transport#GO:0099111;anatomical structure development#GO:0048856;cellular localization#GO:0051641;localization#GO:0051179;multicellular organismal reproductive process#GO:0048609;axo-dendritic transport#GO:0008088;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;intracellular transport#GO:0046907;transport#GO:0006810;developmental process#GO:0032502;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;protein localization to synapse#GO:0035418;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104 cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell body#GO:0044297;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016507.1|UniProtKB=W5NID1 W5NID1 PTHR12756:SF23 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 3 binding#GO:0005488;metallopeptidase activity#GO:0008237;protein binding#GO:0005515;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000012180.1|UniProtKB=W5N2Z9 W5N2Z9 PTHR14166:SF6 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 2-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of cell migration#GO:0030334;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;multicellular organism development#GO:0007275;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;regulation of cell motility#GO:2000145;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128 dendritic spine#GO:0043197;neuron projection#GO:0043005;postsynapse#GO:0098794;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;dendritic tree#GO:0097447;dendrite#GO:0030425;cell junction#GO:0030054 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000015275.1|UniProtKB=W5NDU0 W5NDU0 PTHR46071:SF1 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT- AND BTB_POZ DOMAIN-CONTAINING PROTEIN 3 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004945.1|UniProtKB=W5MC38 W5MC38 PTHR46103:SF3 RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;rRNA (guanine) methyltransferase activity#GO:0016435;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a rRNA#GO:0140102;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000005235.1|UniProtKB=W5MD46 W5MD46 PTHR43289:SF13 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED SERINE_THREONINE-PROTEIN KINASE NEK6 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of chromosome organization#GO:0033044;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic cell cycle phase transition#GO:1901990;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012004.1|UniProtKB=W5N2B2 W5N2B2 PTHR13844:SF2 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ATPase complex#GO:1904949;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000010545.1|UniProtKB=W5MX22 W5MX22 PTHR11849:SF77 ETS TRANSCRIPTION FACTOR ETV7 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000018106.1|UniProtKB=W5NNJ8 W5NNJ8 PTHR17070:SF0 DEXAMETHASONE-INDUCED PROTEIN DEXAMETHASONE-INDUCED PROTEIN LEPOC|Ensembl=ENSLOCG00000018328.1|UniProtKB=W5NP70 W5NP70 PTHR23074:SF75 AAA DOMAIN-CONTAINING FIDGETIN-LIKE PROTEIN 1 ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004221.1|UniProtKB=W5M9J4 W5M9J4 PTHR31183:SF2 TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987;programmed cell death#GO:0012501 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000000078.1|UniProtKB=W5LVD2 W5LVD2 B4GALT1 PTHR19300:SF5 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000008961.1|UniProtKB=W5MRB8 W5MRB8 PTHR10027:SF35 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY T MEMBER 2 ISOFORM X1 monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836 transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000007100.1|UniProtKB=W5MJN8 W5MJN8 PTHR10024:SF348 SYNAPTOTAGMIN SYNAPTOTAGMIN-17 SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;molecular sensor activity#GO:0140299 regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;localization#GO:0051179;transport#GO:0006810;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008479.1|UniProtKB=W5MPL7 W5MPL7 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016665.1|UniProtKB=W5NIX6 W5NIX6 PTHR31909:SF2 CHROMOSOME 20 ORF85 FAMILY MEMBER CILIARY MICROTUBULE INNER PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000017704.1|UniProtKB=W5NMF0 W5NMF0 PTHR16081:SF0 VERTNIN VERTNIN regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000011422.1|UniProtKB=W5N078 W5N078 PTHR15603:SF1 SH3 DOMAIN-CONTAINING PROTEIN METASTASIS-ASSOCIATED IN COLON CANCER PROTEIN 1 DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015154.1|UniProtKB=W5NDE2 W5NDE2 PTHR11036:SF80 SEMAPHORIN SEMAPHORIN-7A cell adhesion molecule binding#GO:0050839;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;integrin binding#GO:0005178;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;integrin-mediated signaling pathway#GO:0007229;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of response to external stimulus#GO:0032101;taxis#GO:0042330;response to chemical#GO:0042221;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;chemotaxis#GO:0006935;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;locomotion#GO:0040011;regulation of response to stress#GO:0080134;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000008804.1|UniProtKB=W5MQQ7 W5MQQ7 PTHR46150:SF2 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN SYDE1 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of Ras protein signal transduction#GO:0046578;regulation of small GTPase mediated signal transduction#GO:0051056;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cell migration#GO:0016477;cell motility#GO:0048870 cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009905.1|UniProtKB=W5MUQ4 W5MUQ4 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003841.1|UniProtKB=W5M881 W5M881 PTHR15352:SF2 LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1 INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007694.1|UniProtKB=W5MLV3 W5MLV3 PTHR10514:SF24 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME 2 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;proteolysis#GO:0006508;circulatory system process#GO:0003013;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;system process#GO:0003008;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biological regulation#GO:0065007;biosynthetic process#GO:0009058;blood circulation#GO:0008015;hormone metabolic process#GO:0042445;protein maturation#GO:0051604;gene expression#GO:0010467;multicellular organismal process#GO:0032501;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000036.1|UniProtKB=W5LV83 W5LV83 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011235.1|UniProtKB=W5MZJ1 W5MZJ1 PTHR46595:SF2 60S RIBOSOMAL PROTEIN L34 LARGE RIBOSOMAL SUBUNIT PROTEIN EL34 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010869.1|UniProtKB=W5MY62 W5MY62 PTHR11889:SF39 HEDGEHOG INDIAN HEDGEHOG PROTEIN protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;signaling receptor binding#GO:0005102;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell fate specification#GO:0001708;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;smoothened signaling pathway#GO:0007224;cell fate commitment#GO:0045165;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007238.1|UniProtKB=W5MK52 W5MK52 PTHR16675:SF237 MHC CLASS I-RELATED MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000003074.1|UniProtKB=W5M5F3 W5M5F3 PTHR21687:SF5 PLASMALEMMA VESICLE-ASSOCIATED PROTEIN PLASMALEMMA VESICLE-ASSOCIATED PROTEIN regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of leukocyte migration#GO:0002685;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;regulation of cell motility#GO:2000145;positive regulation of cell migration#GO:0030335;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of immune system process#GO:0002684;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;regulation of cell migration#GO:0030334;system process#GO:0003008;positive regulation of locomotion#GO:0040017 LEPOC|Ensembl=ENSLOCG00000009043.1|UniProtKB=W5MRL2 W5MRL2 PTHR12480:SF35 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN 8 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005689.1|UniProtKB=W5MEQ9 W5MEQ9 PTHR33767:SF2 LEUCINE RICH ADAPTOR PROTEIN 1-LIKE LEUCINE RICH ADAPTOR PROTEIN 1 positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of biosynthetic process#GO:0009889 LEPOC|Ensembl=ENSLOCG00000014979.1|UniProtKB=W5NCT3 W5NCT3 PTHR11259:SF1 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 negative regulation of catabolic process#GO:0009895;positive regulation of TOR signaling#GO:0032008;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to stress#GO:0006950 lysosome#GO:0005764;nucleus#GO:0005634;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000003996.1|UniProtKB=W5M8S0 W5M8S0 PTHR23086:SF35 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 GAMMA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 kinase#PC00137;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000005861.1|UniProtKB=W5MFB7 W5MFB7 PTHR13219:SF6 TRANSMEMBRANE PROTEIN 94 TRANSMEMBRANE PROTEIN 94 monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;magnesium ion transmembrane transporter activity#GO:0015095;primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;magnesium ion transport#GO:0015693;intracellular transport#GO:0046907 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001695.1|UniProtKB=W5M0P8 W5M0P8 PTHR10127:SF899 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING ASTACIN-LIKE METALLOENDOPEPTIDASE-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000011431.1|UniProtKB=W5N095 W5N095 PTHR10082:SF9 INTEGRIN BETA SUBUNIT INTEGRIN BETA-8 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell adhesion mediated by integrin#GO:0033627;cell surface receptor signaling pathway#GO:0007166;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;cell migration#GO:0016477;biological regulation#GO:0065007;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;integrin complex#GO:0008305;cell junction#GO:0030054;anchoring junction#GO:0070161 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 LEPOC|Ensembl=ENSLOCG00000007308.1|UniProtKB=W5MKE4 W5MKE4 PTHR14388:SF9 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 2A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell activation#GO:0001775;cellular process#GO:0009987;T cell activation#GO:0042110;immune system process#GO:0002376;leukocyte activation#GO:0045321;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 VEGF signaling pathway#P00056>VRAP#P01405;Angiogenesis#P00005>VRAP#P00196 LEPOC|Ensembl=ENSLOCG00000018090.1|UniProtKB=W5NNI2 W5NNI2 PTHR11767:SF14 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 12-RELATED passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000009030.1|UniProtKB=W5MRJ6 W5MRJ6 PTHR24103:SF667 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM69 ISOFORM X1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013435.1|UniProtKB=W5N7F6 W5N7F6 PTHR47992:SF274 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE MN(2+)-DEPENDENT 1K hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000000194.1|UniProtKB=W5LVR1 W5LVR1 PTHR12951:SF6 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG B-B ISOFORM X8 lipid binding#GO:0008289;binding#GO:0005488 organelle assembly#GO:0070925;localization#GO:0051179;cell cycle#GO:0007049;negative regulation of cellular component organization#GO:0051129;cell division#GO:0051301;mitotic cell cycle#GO:0000278;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;macromolecule localization#GO:0033036;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;cilium organization#GO:0044782;protein transport#GO:0015031;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cell cycle process#GO:0022402;regulation of receptor-mediated endocytosis#GO:0048259;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of endocytosis#GO:0030100;cellular component organization or biogenesis#GO:0071840;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spindle pole#GO:0000922 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009686.1|UniProtKB=W5MTX1 W5MTX1 PTHR23037:SF52 CYTOKINE RECEPTOR GROWTH HORMONE RECEPTOR ISOFORM X1 immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013375.1|UniProtKB=W5N7C9 W5N7C9 PTHR10676:SF183 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 2 catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777 cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;dynein complex#GO:0030286;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001625.1|UniProtKB=W5M0H6 W5M0H6 PTHR12911:SF23 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000004692.1|UniProtKB=W5MB60 W5MB60 PTHR10985:SF161 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;pattern specification process#GO:0007389;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;circulatory system development#GO:0072359;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;anterior/posterior pattern specification#GO:0009952;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000011870.1|UniProtKB=W5N1T4 W5N1T4 PTHR47091:SF2 ALPHA-PROTEIN KINASE 2-RELATED ALPHA-PROTEIN KINASE 2 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006542.1|UniProtKB=W5MHQ1 W5MHQ1 PTHR23053:SF0 DLEC1 DELETED IN LUNG AND ESOPHAGEAL CANCER 1 AXONEMAL CENTRAL PAIR APPARATUS PROTEIN HYDIN organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;cilium movement#GO:0003341;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;axoneme assembly#GO:0035082;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010 organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000009198.1|UniProtKB=W5MS62 W5MS62 PTHR20933:SF3 F-BOX ONLY PROTEIN 33 F-BOX ONLY PROTEIN 33 regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399 LEPOC|Ensembl=ENSLOCG00000002091.1|UniProtKB=W5M265 W5M265 PTHR10574:SF270 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-1 cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000016012.1|UniProtKB=W5NGG9 W5NGG9 PTHR13018:SF24 PROBABLE MEMBRANE PROTEIN DUF221-RELATED MECHANOSENSITIVE CATION CHANNEL TMEM63A passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;calcium-activated cation channel activity#GO:0005227;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015946.1|UniProtKB=W5NG77 W5NG77 PTHR21780:SF0 TRANSMEMBRANE PROTEIN 209 TRANSMEMBRANE PROTEIN 209 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000017053.1|UniProtKB=W5NKC5 W5NKC5 PTHR12308:SF20 ANOCTAMIN ANOCTAMIN-2 gated channel activity#GO:0022836;molecular carrier activity#GO:0140104;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;ligand-gated monoatomic ion channel activity#GO:0015276;lipid carrier activity#GO:0005319;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;chloride transport#GO:0006821;transport#GO:0006810;lipid transport#GO:0006869;monoatomic anion transmembrane transport#GO:0098656;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;monoatomic ion transmembrane transport#GO:0034220;macromolecule localization#GO:0033036;cellular process#GO:0009987;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;monoatomic anion transport#GO:0006820;cellular component organization#GO:0016043 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012686.1|UniProtKB=W5N4P7 W5N4P7 PTHR32014:SF2 BCL-2-MODIFYING FACTOR BCL-2-MODIFYING FACTOR regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;positive regulation of apoptotic process#GO:0043065;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of catabolic process#GO:0009895;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007671.1|UniProtKB=W5MLQ8 W5MLQ8 PTHR10915:SF3 SYNDECAN SYNDECAN-4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115 anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell surface#GO:0009986 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015982.1|UniProtKB=W5NGC0 W5NGC0 PTHR11102:SF147 SEL-1-LIKE PROTEIN PROTEIN SEL-1 HOMOLOG 1 protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000006011.1|UniProtKB=W5MFW0 W5MFW0 PTHR22938:SF0 ZINC FINGER PROTEIN 598 E3 UBIQUITIN-PROTEIN LIGASE ZNF598 ubiquitin-like protein ligase activity#GO:0061659;protein-containing complex binding#GO:0044877;ubiquitin-protein transferase activity#GO:0004842;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule modification#GO:0043412;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;protein modification by small protein conjugation or removal#GO:0070647;translation#GO:0006412;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein modification process#GO:0036211;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;rescue of stalled cytosolic ribosome#GO:0072344;protein modification by small protein conjugation#GO:0032446;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;translational elongation#GO:0006414;metabolic process#GO:0008152;gene expression#GO:0010467;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001954.1|UniProtKB=W5M1L7 W5M1L7 PTHR11576:SF16 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 enzyme binding#GO:0019899;extracellular matrix structural constituent#GO:0005201;binding#GO:0005488;structural molecule activity#GO:0005198;protein binding#GO:0005515 cellular developmental process#GO:0048869;cell-cell recognition#GO:0009988;sperm-egg recognition#GO:0035036;developmental process#GO:0032502;regulation of reproductive process#GO:2000241;biological regulation#GO:0065007;oogenesis#GO:0048477;single fertilization#GO:0007338;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;anatomical structure development#GO:0048856;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;cell recognition#GO:0008037;cell differentiation#GO:0030154;gamete generation#GO:0007276;reproductive process#GO:0022414;fertilization#GO:0009566;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;germ cell development#GO:0007281 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001855.1|UniProtKB=W5M1B0 W5M1B0 PTHR45620:SF7 PDF RECEPTOR-LIKE PROTEIN-RELATED PARATHYROID HORMONE 2 RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011848.1|UniProtKB=W5N1R3 W5N1R3 PTHR19919:SF0 WD REPEAT CONTAINING PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 7 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000013777.1|UniProtKB=W5N8N0 W5N8N0 PTHR23035:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97 LEPOC|Ensembl=ENSLOCG00000004034.1|UniProtKB=W5M8W2 W5M8W2 PTHR43215:SF18 RADIAL SPOKE HEAD 1 HOMOLOG RADIAL SPOKE HEAD 1 HOMOLOG spermatid differentiation#GO:0048515;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;reproductive process#GO:0022414;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036 organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000006866.1|UniProtKB=W5MIU5 W5MIU5 PTHR11339:SF384 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-2 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000003961.1|UniProtKB=W5M8M6 W5M8M6 PTHR10125:SF4 P2X PURINOCEPTOR P2X PURINOCEPTOR 2 monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000012387.1|UniProtKB=W5N3P5 W5N3P5 PTHR44324:SF3 WD40 REPEAT DOMAIN 95 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 337 LEPOC|Ensembl=ENSLOCG00000004085.1|UniProtKB=W5M919 W5M919 PTHR24250:SF66 CHYMOTRYPSIN-RELATED CHYMOTRYPSIN-LIKE PROTEASE CTRL-1 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protein modifying enzyme#PC00260;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000015106.1|UniProtKB=W5ND85 W5ND85 PTHR44809:SF1 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE TMTC1 glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000015163.1|UniProtKB=W5NDF3 W5NDF3 PTHR11937:SF47 ACTIN ACTIN-RELATED PROTEIN 6 protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;nucleolus organization#GO:0007000;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840 ATPase complex#GO:1904949;Swr1 complex#GO:0000812;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 actin and actin related protein#PC00039 LEPOC|Ensembl=ENSLOCG00000003252.1|UniProtKB=W5M633 W5M633 PTHR31817:SF1 FAMILY NOT NAMED MICROTUBULE-ASSOCIATED TYROSINE CARBOXYPEPTIDASE 1 LEPOC|Ensembl=ENSLOCG00000015209.1|UniProtKB=W5NDK9 W5NDK9 PTHR12639:SF6 VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;lyase activity#GO:0016829 cellular process#GO:0009987;metabolic process#GO:0008152;vitamin K metabolic process#GO:0042373;ketone metabolic process#GO:0042180 LEPOC|Ensembl=ENSLOCG00000009379.1|UniProtKB=W5MST1 W5MST1 PTHR12322:SF76 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 sex differentiation#GO:0007548;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009603.1|UniProtKB=W5MTM7 W5MTM7 PTHR23302:SF17 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 2 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267 system process#GO:0003008;response to external stimulus#GO:0009605;detection of mechanical stimulus#GO:0050982;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to mechanical stimulus#GO:0009612 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000005118.1|UniProtKB=W5MCS9 W5MCS9 PTHR44140:SF3 LD25575P DNAJ HOMOLOG SUBFAMILY C MEMBER 3 protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000009301.1|UniProtKB=W5MSI9 W5MSI9 PTHR11003:SF330 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM TWO PORE DOMAIN CHANNEL SUBFAMILY K MEMBER 4 transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000007422.1|UniProtKB=W5MKV0 W5MKV0 PTHR12027:SF104 WNT RELATED PROTEIN WNT G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515 signaling#GO:0023052;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell fate commitment#GO:0045165;system development#GO:0048731;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007500.1|UniProtKB=W5ML45 W5ML45 PTHR23189:SF46 RNA RECOGNITION MOTIF-CONTAINING RIBONUCLEOPROTEIN PTB-BINDING 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017154.1|UniProtKB=W5NKQ3 W5NKQ3 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009027.1|UniProtKB=W5MRJ2 W5MRJ2 PTHR14168:SF6 TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER EPITHELIAL CELL ADHESION MOLECULE cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000001435.1|UniProtKB=W5LZS8 W5LZS8 PTHR34524:SF1 CALCYPHOSIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 68 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000015516.1|UniProtKB=W5NEN5 W5NEN5 PTHR22748:SF6 AP ENDONUCLEASE DNA REPAIR NUCLEASE_REDOX REGULATOR APEX1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;DNA exonuclease activity#GO:0004529;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;DNA endonuclease activity#GO:0004520;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;base-excision repair#GO:0006284;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 LEPOC|Ensembl=ENSLOCG00000004569.1|UniProtKB=W5MAT3 W5MAT3 PTHR10336:SF173 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-1 phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;lipase activity#GO:0016298 phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell motility#GO:2000145;localization#GO:0051179;monoatomic cation transport#GO:0006812;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;monoatomic ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;organophosphate metabolic process#GO:0019637;positive regulation of locomotion#GO:0040017;establishment of localization#GO:0051234;regulation of cell migration#GO:0030334;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;transport#GO:0006810;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transmembrane transport#GO:0098655;regulation of multicellular organismal process#GO:0051239;glycerophospholipid metabolic process#GO:0006650;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;metabolic process#GO:0008152 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection membrane#GO:0031253;ruffle#GO:0001726;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587 lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186;hydrolase#PC00121 5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;PDGF signaling pathway#P00047>PLCgamma#P01171;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;EGF receptor signaling pathway#P00018>PLCgamma#P00556;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;FGF signaling pathway#P00021>PLCgamma#P00638;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Angiogenesis#P00005>PLC-gamma#P00256;CCKR signaling map#P06959>PLCgamma1#P07037;T cell activation#P00053>PLC-gamma#P01320;VEGF signaling pathway#P00056>PLC-gamma#P01414 LEPOC|Ensembl=ENSLOCG00000004050.1|UniProtKB=W5M8Z7 W5M8Z7 PTHR12371:SF3 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 1 localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein insertion into membrane#GO:0051205 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000014074.1|UniProtKB=W5N9N6 W5N9N6 PTHR10361:SF41 SODIUM-BILE ACID COTRANSPORTER SODIUM_BILE ACID COTRANSPORTER 4-RELATED carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;bile acid transmembrane transporter activity#GO:0015125;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 lipid transport#GO:0006869;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;localization#GO:0051179;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;bile acid and bile salt transport#GO:0015721;lipid localization#GO:0010876 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000001445.1|UniProtKB=W5LZU7 W5LZU7 PTHR10185:SF26 PHOSPHOLIPASE D - RELATED 5'-3' EXONUCLEASE PLD3 ISOFORM X1 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000008587.1|UniProtKB=W5MPY2 W5MPY2 PTHR14154:SF154 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 2 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 intracellular transport#GO:0046907;mitochondrial transmembrane transport#GO:1990542;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 LEPOC|Ensembl=ENSLOCG00000001283.1|UniProtKB=W5LZ93 W5LZ93 PTHR11539:SF0 VDJ RECOMBINATION ACTIVATING PROTEIN 1 RAG1 V(D)J RECOMBINATION-ACTIVATING PROTEIN 1 endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016113.1|UniProtKB=W5NGU6 W5NGU6 PTHR12270:SF48 GLYCOSYLTRANSFERASE-RELATED XYLOSYL- AND GLUCURONYLTRANSFERASE LARGE1 pentosyltransferase activity#GO:0016763;glucuronosyltransferase activity#GO:0015020;xylosyltransferase activity#GO:0042285;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008843.1|UniProtKB=W5MQV4 W5MQV4 PTHR24104:SF31 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED NHL REPEAT-CONTAINING PROTEIN 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 LEPOC|Ensembl=ENSLOCG00000009981.1|UniProtKB=W5MV21 W5MV21 PTHR14102:SF12 PAR-6-RELATED CDNA SEQUENCE BC034090 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell cycle process#GO:0022402;cellular process#GO:0009987;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;establishment or maintenance of cell polarity#GO:0007163;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cell-cell junction maintenance#GO:0045217;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;apical part of cell#GO:0045177;transferase complex#GO:1990234;protein kinase complex#GO:1902911;apical plasma membrane#GO:0016324;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000005723.1|UniProtKB=W5MEV9 W5MEV9 PTHR46877:SF17 EPH RECEPTOR A5 EPHRIN TYPE-B RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 LEPOC|Ensembl=ENSLOCG00000012567.1|UniProtKB=W5N4B2 W5N4B2 PTHR12322:SF71 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;sex differentiation#GO:0007548;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015617.1|UniProtKB=W5NF20 W5NF20 PTHR24023:SF918 COLLAGEN ALPHA COLLAGEN ALPHA-1(IX) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000002862.1|UniProtKB=W5M4Q9 W5M4Q9 PTHR19300:SF9 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 4 glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000015688.1|UniProtKB=W5NFA4 W5NFA4 PTHR10920:SF12 RIBOSOMAL RNA METHYLTRANSFERASE TRNA (CYTIDINE(32)_GUANOSINE(34)-2'-O)-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000001289.1|UniProtKB=W5LZA3 W5LZA3 PTHR21183:SF18 RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000011954.1|UniProtKB=W5N241 W5N241 PTHR24056:SF459 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 13 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000015150.1|UniProtKB=W5NDD4 W5NDD4 PTHR31281:SF2 PROTEIN FAM219A PROTEIN FAM219B LEPOC|Ensembl=ENSLOCG00000016425.1|UniProtKB=W5NI28 W5NI28 PTHR10554:SF3 SYNTROPHIN GAMMA-2-SYNTROPHIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016098.1|UniProtKB=W5NGS7 W5NGS7 PTHR48020:SF55 PROTON MYO-INOSITOL COTRANSPORTER PROTON MYO-INOSITOL COTRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078 cellular process#GO:0009987;transport#GO:0006810;organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005756.1|UniProtKB=W5MEZ5 W5MEZ5 PTHR11732:SF294 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014916.1|UniProtKB=W5NCL0 W5NCL0 PTHR22968:SF12 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE D2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;EGF receptor signaling pathway#P00018>PKC#P00565;CCKR signaling map#P06959>PRKD2#P07216 LEPOC|Ensembl=ENSLOCG00000016620.1|UniProtKB=W5NIS1 W5NIS1 PTHR11328:SF30 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN SPHINGOSINE-1-PHOSPHATE TRANSPORTER MFSD2B lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000015859.1|UniProtKB=W5NFW7 W5NFW7 PTHR11769:SF7 HYALURONIDASE HYALURONIDASE-4 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;glycosaminoglycan catabolic process#GO:0006027;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000004602.1|UniProtKB=W5MAV6 W5MAV6 PTHR11743:SF12 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL NON-SELECTIVE VOLTAGE-GATED ION CHANNEL VDAC2 channel activity#GO:0015267;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 mitochondrial transport#GO:0006839;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542;intracellular transport#GO:0046907 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000015505.1|UniProtKB=W5NEM6 W5NEM6 PTHR38537:SF5 JITTERBUG, ISOFORM N FILAMIN-A Integrin signalling pathway#P00034>Filamin#P00914;Nicotine pharmacodynamics pathway#P06587>FLNA#P06601;Dopamine receptor mediated signaling pathway#P05912>FLNA#P05959 LEPOC|Ensembl=ENSLOCG00000008490.1|UniProtKB=W5MPM1 W5MPM1 PTHR21038:SF2 40-2-3 PROTEIN-RELATED UAP56-INTERACTING FACTOR protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nucleocytoplasmic transport#GO:0006913;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membraneless organelle#GO:0043228;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000012648.1|UniProtKB=W5N4K9 W5N4K9 PTHR24006:SF672 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005069.1|UniProtKB=W5MCJ3 W5MCJ3 PTHR11818:SF38 BETA/GAMMA CRYSTALLIN VERY LARGE A-KINASE ANCHOR PROTEIN structural molecule activity#GO:0005198 visual system development#GO:0150063;visual perception#GO:0007601;sensory perception of light stimulus#GO:0050953;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011641.1|UniProtKB=W5N104 W5N104 PTHR23167:SF98 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL1 oxidoreductase activity#GO:0016491;cytoskeletal protein binding#GO:0008092;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament depolymerization#GO:0030042;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;protein depolymerization#GO:0051261;actin cytoskeleton organization#GO:0030036 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014106.1|UniProtKB=W5N9S0 W5N9S0 PTHR21142:SF2 SARCOGLYCANS BETA-SARCOGLYCAN sarcolemma#GO:0042383;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000009275.1|UniProtKB=W5MSG2 W5MSG2 PTHR24221:SF662 ATP-BINDING CASSETTE SUB-FAMILY B MITOCHONDRIAL POTASSIUM CHANNEL ATP-BINDING SUBUNIT primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000005628.1|UniProtKB=W5MEI8 W5MEI8 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000008484.1|UniProtKB=W5MPM7 W5MPM7 PTHR10644:SF26 DNA REPAIR/RNA PROCESSING CPSF FAMILY CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008658.1|UniProtKB=W5MQ72 W5MQ72 CREB3L4 PTHR45996:SF2 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 LEPOC|Ensembl=ENSLOCG00000000842.1|UniProtKB=W5LXT2 W5LXT2 PTHR13140:SF781 MYOSIN MYOSIN-11 polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;actin cytoskeleton#GO:0015629 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000016583.1|UniProtKB=W5NIM3 W5NIM3 PTHR45678:SF11 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED MITOCHONDRIAL GLUTAMATE CARRIER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000012939.1|UniProtKB=W5N5M5 W5N5M5 PTHR19282:SF184 TETRASPANIN PERIPHERIN 2 LIKE-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005586.1|UniProtKB=W5MED8 W5MED8 PTHR11920:SF506 GUANYLYL CYCLASE GUANYLATE CYCLASE lyase activity#GO:0016829;molecular transducer activity#GO:0060089;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;peptide receptor activity#GO:0001653;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023 phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 lyase#PC00144;guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000003534.1|UniProtKB=W5M725 W5M725 PTHR15860:SF2 UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNFT2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 LEPOC|Ensembl=ENSLOCG00000016143.1|UniProtKB=W5NGY2 W5NGY2 PTHR46186:SF12 CYSTATIN CYSTATIN C (AMYLOID ANGIOPATHY AND CEREBRAL HEMORRHAGE)-RELATED endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000014692.1|UniProtKB=W5NBS5 W5NBS5 PTHR24073:SF963 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1A ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;autophagy#GO:0006914;cellular localization#GO:0051641;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;vacuole organization#GO:0007033;organelle assembly#GO:0070925;catabolic process#GO:0009056;cellular component organization#GO:0016043 cell body#GO:0044297;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000011968.1|UniProtKB=W5N275 W5N275 PTHR10082:SF25 INTEGRIN BETA SUBUNIT INTEGRIN BETA-3 protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;integrin-mediated signaling pathway#GO:0007229;hemostasis#GO:0007599;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of body fluid levels#GO:0050878;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell activation#GO:0001775;regulation of biological quality#GO:0065008;wound healing#GO:0042060;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;coagulation#GO:0050817;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;cell-cell adhesion#GO:0098609;response to wounding#GO:0009611;biological regulation#GO:0065007;homotypic cell-cell adhesion#GO:0034109;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cell adhesion mediated by integrin#GO:0033627;platelet aggregation#GO:0070527;cell surface receptor signaling pathway#GO:0007166;blood coagulation#GO:0007596;platelet activation#GO:0030168 cell junction#GO:0030054;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;integrin complex#GO:0008305;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;synapse#GO:0045202;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;membrane protein complex#GO:0098796;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931;Blood coagulation#P00011>GP IIIa#P00458 LEPOC|Ensembl=ENSLOCG00000008913.1|UniProtKB=W5MR42 W5MR42 PTHR11471:SF34 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of signal transduction#GO:0009967;cell communication#GO:0007154;regulation of apoptotic signaling pathway#GO:2001233;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001214.1|UniProtKB=W5LZ12 W5LZ12 PTHR18843:SF7 TORSIN-1A-INTERACTING PROTEIN SI:DKEYP-82A1.6 membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002451.1|UniProtKB=W5M3C1 W5M3C1 PTHR12487:SF3 TEASHIRT-RELATED TEASHIRT HOMOLOG 2 transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007299.1|UniProtKB=W5MKE7 W5MKE7 PTHR22932:SF3 TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE PROSTAGLANDIN E SYNTHASE 3 protein-folding chaperone binding#GO:0051087;catalytic activity#GO:0003824;heat shock protein binding#GO:0031072;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;binding#GO:0005488;Hsp90 protein binding#GO:0051879;protein binding#GO:0005515 cellular component organization#GO:0016043;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;protein-containing complex assembly#GO:0065003;small molecule metabolic process#GO:0044281;ribonucleoprotein complex biogenesis#GO:0022613;protein folding#GO:0006457;oxoacid metabolic process#GO:0043436;nucleic acid biosynthetic process#GO:0141187;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;telomere maintenance via telomere lengthening#GO:0010833;icosanoid metabolic process#GO:0006690;telomere maintenance via telomerase#GO:0007004;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;icosanoid biosynthetic process#GO:0046456;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;unsaturated fatty acid metabolic process#GO:0033559;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;carboxylic acid biosynthetic process#GO:0046394;chaperone-mediated protein complex assembly#GO:0051131;prostaglandin metabolic process#GO:0006693;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;telomere organization#GO:0032200;macromolecule biosynthetic process#GO:0009059;lipid biosynthetic process#GO:0008610;unsaturated fatty acid biosynthetic process#GO:0006636;fatty acid biosynthetic process#GO:0006633;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;RNA-templated DNA biosynthetic process#GO:0006278;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016285.1|UniProtKB=W5NHJ0 W5NHJ0 PTHR48092:SF16 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN RECEPTOR sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;intracellular receptor signaling pathway#GO:0030522;response to steroid hormone#GO:0048545;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular response to steroid hormone stimulus#GO:0071383;estrogen receptor signaling pathway#GO:0030520;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012961.1|UniProtKB=W5N5Q2 W5N5Q2 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;enzyme binding#GO:0019899;extracellular matrix structural constituent#GO:0005201 sexual reproduction#GO:0019953;cell recognition#GO:0008037;multicellular organismal reproductive process#GO:0048609;binding of sperm to zona pellucida#GO:0007339;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;cellular process involved in reproduction in multicellular organism#GO:0022412;fertilization#GO:0009566;reproductive process#GO:0022414;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276;developmental process#GO:0032502;sperm-egg recognition#GO:0035036;cell-cell recognition#GO:0009988;cellular developmental process#GO:0048869;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;single fertilization#GO:0007338;biological regulation#GO:0065007;oogenesis#GO:0048477;regulation of reproductive process#GO:2000241 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000015473.1|UniProtKB=W5NEI6 W5NEI6 PTHR10338:SF155 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H6 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000012208.1|UniProtKB=W5N310 W5N310 PTHR11227:SF18 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 3 phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;vacuole organization#GO:0007033;localization#GO:0051179;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;energy derivation by oxidation of organic compounds#GO:0015980;polysaccharide catabolic process#GO:0000272;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015409.1|UniProtKB=W5NEA7 W5NEA7 PTHR14221:SF72 WD REPEAT DOMAIN 44 WD REPEAT-CONTAINING PROTEIN 44 cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;regulation of localization#GO:0032879 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000014075.1|UniProtKB=W5N9N9 W5N9N9 PTHR23003:SF63 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE_ARGININE-RICH SPLICING FACTOR 5 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000005298.1|UniProtKB=W5MDC6 W5MDC6 PTHR24049:SF19 CRUMBS FAMILY MEMBER PROTEIN CRUMBS HOMOLOG 2 establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;establishment or maintenance of bipolar cell polarity#GO:0061245;cell adhesion#GO:0007155;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of cell polarity#GO:0007163;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012729.1|UniProtKB=W5N4V5 W5N4V5 PTHR46345:SF8 INVERTED FORMIN-2 INVERTED FORMIN-2 LEPOC|Ensembl=ENSLOCG00000001621.1|UniProtKB=W5M0G3 W5M0G3 PTHR43389:SF1 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B, KIDNEY ISOFORM regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting two-sector ATPase complex#GO:0016469;apical part of cell#GO:0045177;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494 primary active transporter#PC00068;ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000005721.1|UniProtKB=W5MEU7 W5MEU7 PTHR21228:SF59 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 4 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 mitochondrial RNA metabolic process#GO:0000959;regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;nucleic acid biosynthetic process#GO:0141187;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000013983.1|UniProtKB=W5N9C7 W5N9C7 PTHR13174:SF3 D-GLUCURONYL C5-EPIMERASE D-GLUCURONYL C5-EPIMERASE catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 isomerase#PC00135 LEPOC|Ensembl=ENSLOCG00000014535.1|UniProtKB=W5NB82 W5NB82 PTHR43721:SF11 ELONGATION FACTOR TU-RELATED SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 protein biosynthetic process#GO:0160307;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;translation#GO:0006412;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;translational elongation#GO:0006414;metabolic process#GO:0008152 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000017932.1|UniProtKB=W5NN26 W5NN26 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014421.1|UniProtKB=W5NAU6 W5NAU6 PTHR11769:SF36 HYALURONIDASE HYALURONIDASE carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosaminoglycan metabolic process#GO:0030203;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;glycosaminoglycan catabolic process#GO:0006027;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000017815.1|UniProtKB=W5NMR0 W5NMR0 PTHR23257:SF706 SERINE-THREONINE PROTEIN KINASE PROTO-ONCOGENE SERINE_THREONINE-PROTEIN KINASE MOS transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 cell communication#GO:0007154;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell cycle phase transition#GO:1901987;negative regulation of chromosome separation#GO:1905819;positive regulation of MAPK cascade#GO:0043410;negative regulation of cell cycle process#GO:0010948;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of cell cycle#GO:0045786;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of MAPK cascade#GO:0043408;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012394.1|UniProtKB=W5N3R1 W5N3R1 PTHR12450:SF27 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 FAM20A GOLGI ASSOCIATED SECRETORY PATHWAY PSEUDOKINASE enzyme regulator activity#GO:0030234;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein kinase activator activity#GO:0030295 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003935.1|UniProtKB=W5M8K5 W5M8K5 PES1 PTHR12221:SF6 PESCADILLO - RELATED PESCADILLO HOMOLOG RNA binding#GO:0003723;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;90S preribosome#GO:0030686;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005131.1|UniProtKB=W5MCT8 W5MCT8 PTHR11935:SF77 BETA LACTAMASE DOMAIN HYDROXYACYLGLUTATHIONE HYDROLASE-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000003807.1|UniProtKB=W5M865 W5M865 PTHR24023:SF845 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXII) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000013756.1|UniProtKB=W5N8K2 W5N8K2 PTHR32222:SF1 CENTROMERE PROTEIN U CENTROMERE PROTEIN U membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000004662.1|UniProtKB=W5MB21 W5MB21 PTHR21093:SF4 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1A LEPOC|Ensembl=ENSLOCG00000013457.1|UniProtKB=W5N7I1 W5N7I1 PTHR45804:SF6 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-B13 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013020.1|UniProtKB=W5N5Y9 W5N5Y9 PTHR16154:SF24 NEURABIN NEURABIN-2 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;actin filament organization#GO:0007015;calcium-mediated signaling#GO:0019722;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cellular response to stimulus#GO:0051716;system development#GO:0048731;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029 asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;postsynapse#GO:0098794;cell cortex#GO:0005938;actin-based cell projection#GO:0098858;intracellular anatomical structure#GO:0005622;filopodium#GO:0030175;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000007355.1|UniProtKB=W5MKK7 W5MKK7 PTHR22881:SF12 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN-CONTAINING PROTEIN 7 histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008419.1|UniProtKB=W5MPC6 W5MPC6 PTHR12052:SF5 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4A gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016398.1|UniProtKB=W5NHZ1 W5NHZ1 PTHR10778:SF13 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000004579.1|UniProtKB=W5MAT0 W5MAT0 PTHR24083:SF184 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-ALPHA signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 cellular response to hormone stimulus#GO:0032870;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;nervous system development#GO:0007399;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;intracellular receptor signaling pathway#GO:0030522;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;system development#GO:0048731;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000003098.1|UniProtKB=W5M5K5 W5M5K5 PTHR18952:SF95 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 4 catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 cell periphery#GO:0071944;membrane#GO:0016020;apical plasma membrane#GO:0016324;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;apical part of cell#GO:0045177;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000006066.1|UniProtKB=W5MG15 W5MG15 PTHR10127:SF899 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING ASTACIN-LIKE METALLOENDOPEPTIDASE-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011201.1|UniProtKB=W5MZF8 W5MZF8 PTHR48066:SF2 CARNOSINE SYNTHASE 1 CARNOSINE SYNTHASE-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000005222.1|UniProtKB=W5MD34 W5MD34 PTHR10102:SF28 DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on RNA#GO:0140098;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;mitochondrial transcription#GO:0006390;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;RNA polymerase complex#GO:0030880;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000006038.1|UniProtKB=W5MFY2 W5MFY2 PTHR10838:SF8 SYNAPTOGYRIN SYNAPTOGYRIN-3 transport#GO:0006810;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;secretion by cell#GO:0032940;secretion#GO:0046903;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular process#GO:0009987;cellular component organization#GO:0016043;synaptic vesicle membrane organization#GO:0048499;membrane organization#GO:0061024;export from cell#GO:0140352;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;neuromuscular junction#GO:0031594;cell junction#GO:0030054;cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle#GO:0030133;presynapse#GO:0098793;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008491.1|UniProtKB=W5MPM5 W5MPM5 PTHR24234:SF15 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G PROTEIN-COUPLED RECEPTOR 65 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002272.1|UniProtKB=W5M2P7 W5M2P7 PTHR46104:SF1 GENE 9195-RELATED-RELATED GENE 9195-RELATED LEPOC|Ensembl=ENSLOCG00000005384.1|UniProtKB=W5MDN1 W5MDN1 PTHR43888:SF31 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 2 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;ATPase activator activity#GO:0001671;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;cellular response to heat#GO:0034605;response to heat#GO:0009408;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;protein maturation#GO:0051604;gene expression#GO:0010467;cellular response to stress#GO:0033554;protein refolding#GO:0042026;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;protein folding#GO:0006457;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008160.1|UniProtKB=W5MNG9 W5MNG9 PTHR18966:SF99 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 2 extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943 synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154 signaling receptor complex#GO:0043235;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;neuron spine#GO:0044309;cell projection#GO:0042995;postsynapse#GO:0098794;dendritic spine#GO:0043197 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu2#P01017;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 LEPOC|Ensembl=ENSLOCG00000001205.1|UniProtKB=W5LZ39 W5LZ39 PTHR10314:SF194 CYSTATHIONINE BETA-SYNTHASE CYSTATHIONINE BETA-SYNTHASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;lyase#PC00144 Cysteine biosynthesis#P02737>O-Acetylserine-lyase#P02887 LEPOC|Ensembl=ENSLOCG00000005972.1|UniProtKB=W5MFS3 W5MFS3 PTHR24028:SF335 CADHERIN-87A SI:DKEY-22O22.2 cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000015302.1|UniProtKB=W5NDZ4 W5NDZ4 PTHR45816:SF3 MIR DOMAIN-CONTAINING PROTEIN INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR LEPOC|Ensembl=ENSLOCG00000008283.1|UniProtKB=W5MNV9 W5MNV9 PTHR23337:SF3 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1 ATPASE MORC2 LEPOC|Ensembl=ENSLOCG00000010991.1|UniProtKB=W5MYM5 W5MYM5 PTHR28670:SF1 UV-STIMULATED SCAFFOLD PROTEIN A UV-STIMULATED SCAFFOLD PROTEIN A binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;response to UV#GO:0009411;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to radiation#GO:0009314;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289 cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006172.1|UniProtKB=W5MGE5 W5MGE5 PTHR23267:SF486 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14_DELTA VARIABLE 4 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003988.1|UniProtKB=W5M8Q4 W5M8Q4 PTHR17601:SF1 RAFTLIN-RELATED RAFTLIN-2 LEPOC|Ensembl=ENSLOCG00000002820.1|UniProtKB=W5M4N7 W5M4N7 PTHR13217:SF11 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 5 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;endothelial cell migration#GO:0043542;cell migration#GO:0016477;cell motility#GO:0048870 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008666.1|UniProtKB=W5MQ86 W5MQ86 PTHR16675:SF237 MHC CLASS I-RELATED MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 extracellular region#GO:0005576;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 defense/immunity protein#PC00090;major histocompatibility complex protein#PC00149 LEPOC|Ensembl=ENSLOCG00000005504.1|UniProtKB=W5ME32 W5ME32 PTHR11099:SF0 VACUOLAR SORTING PROTEIN 35 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;endocytic recycling#GO:0032456;cytosolic transport#GO:0016482;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;retrograde transport, endosome to Golgi#GO:0042147;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;endosome to plasma membrane protein transport#GO:0099638;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;retromer complex#GO:0030904;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016029.1|UniProtKB=W5NGI7 W5NGI7 PTHR46857:SF2 EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE F-BOX ONLY PROTEIN 16 LEPOC|Ensembl=ENSLOCG00000001330.1|UniProtKB=W5LZF6 W5LZF6 PTHR10671:SF8 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 3 plasma membrane bounded cell projection assembly#GO:0120031;bleb assembly#GO:0032060;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000015173.1|UniProtKB=W5NDG3 W5NDG3 PTHR13015:SF0 PROTEIN AD-016-RELATED WASH COMPLEX SUBUNIT 3 actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;export from cell#GO:0140352;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;localization#GO:0051179;secretion#GO:0046903;secretion by cell#GO:0032940;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;exocytosis#GO:0006887;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;transport#GO:0006810 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002792.1|UniProtKB=W5M4H5 W5M4H5 PTHR46320:SF1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;amine metabolic process#GO:0009308;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002574.1|UniProtKB=W5M3R5 W5M3R5 PTHR23037:SF63 CYTOKINE RECEPTOR INTERLEUKIN 2 RECEPTOR, GAMMA B ISOFORM X1-RELATED molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;cell communication#GO:0007154;response to peptide#GO:1901652;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;cytokine-mediated signaling pathway#GO:0019221;immune system process#GO:0002376;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;response to chemical#GO:0042221;adaptive immune response#GO:0002250;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009820.1|UniProtKB=W5MUE1 W5MUE1 PTHR48012:SF1 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE OSR1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to chemical stress#GO:0062197;positive regulation of response to external stimulus#GO:0032103;cellular response to abiotic stimulus#GO:0071214;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;regulation of lymphocyte migration#GO:2000401;cellular response to osmotic stress#GO:0071470;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of chemotaxis#GO:0050921;cellular response to stimulus#GO:0051716;hyperosmotic response#GO:0006972;regulation of leukocyte migration#GO:0002685;cellular response to environmental stimulus#GO:0104004;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to osmotic stress#GO:0006970;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017187.1|UniProtKB=W5NKT3 W5NKT3 PTHR31367:SF0 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1B catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine nucleoside metabolic process#GO:0042278;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000012199.1|UniProtKB=W5N2Z4 W5N2Z4 PTHR10159:SF111 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 4 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 anatomical structure development#GO:0048856;cell communication#GO:0007154;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tissue development#GO:0009888;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;formation of primary germ layer#GO:0001704;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;gastrulation#GO:0007369;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of MAPK cascade#GO:0043408;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;endoderm development#GO:0007492;cellular process#GO:0009987;signal transduction#GO:0007165;embryo development#GO:0009790;endoderm formation#GO:0001706;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000000364.1|UniProtKB=W5LWA6 W5LWA6 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001645.1|UniProtKB=W5M0J1 W5M0J1 PTHR10840:SF0 PROGRAMMED CELL DEATH PROTEIN 5 PROGRAMMED CELL DEATH PROTEIN 5 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013011.1|UniProtKB=W5N5W8 W5N5W8 PTHR12931:SF15 UBIQUITIN THIOLESTERASE PROTEIN OTUB UBIQUITIN THIOESTERASE OTUBAIN-LIKE deubiquitinase activity#GO:0101005;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515;ubiquitin binding#GO:0043130;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000005984.1|UniProtKB=W5MFS5 W5MFS5 PTHR47236:SF4 GENE, 32742-RELATED-RELATED GENE, 32742-RELATED LEPOC|Ensembl=ENSLOCG00000003143.1|UniProtKB=W5M5P6 W5M5P6 PTHR16200:SF3 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE ZNRF3 protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;binding#GO:0005488;signaling receptor binding#GO:0005102;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664 regulation of response to stimulus#GO:0048583;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;catabolic process#GO:0009056 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005435.1|UniProtKB=W5MDV5 W5MDV5 PTHR45854:SF1 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of actin filament-based process#GO:0032970;cell migration#GO:0016477;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789 cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;plasma membrane bounded cell projection#GO:0120025;cell junction#GO:0030054;ruffle#GO:0001726;anchoring junction#GO:0070161 LEPOC|Ensembl=ENSLOCG00000015096.1|UniProtKB=W5ND71 W5ND71 PTHR46070:SF3 PINSTRIPE, ISOFORM A DENN DOMAIN-CONTAINING PROTEIN 5B binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 LEPOC|Ensembl=ENSLOCG00000015852.1|UniProtKB=W5NFV8 W5NFV8 PTHR11915:SF449 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN PH DOMAIN-CONTAINING PROTEIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cell development#GO:0048468;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;muscle cell differentiation#GO:0042692;cellular component organization#GO:0016043;muscle cell development#GO:0055001;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular organelle#GO:0043229;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;sarcomere#GO:0030017;cell junction#GO:0030054;membraneless organelle#GO:0043228;I band#GO:0031674;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;cell periphery#GO:0071944;membrane#GO:0016020 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000008078.1|UniProtKB=W5MN52 W5MN52 PTHR24409:SF334 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 653 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000017475.1|UniProtKB=W5NLS1 W5NLS1 PTHR45629:SF16 SNF2/RAD54 FAMILY MEMBER DNA REPAIR AND RECOMBINATION PROTEIN RAD54B catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;homologous recombination#GO:0035825;reproductive process#GO:0022414;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA damage response#GO:0006974;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000003819.1|UniProtKB=W5M852 W5M852 PTHR12259:SF3 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000781.1|UniProtKB=W5LXK8 W5LXK8 PTHR11599:SF53 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-8 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017745.1|UniProtKB=W5NMJ0 W5NMJ0 PTHR11462:SF8 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JUN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;response to steroid hormone#GO:0048545;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;response to lipid#GO:0033993;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of transcription by RNA polymerase II#GO:0045944 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838;T cell activation#P00053>jun#P01335;Angiogenesis#P00005>c-Jun#P00220;CCKR signaling map#P06959>JUN#G07276;Ras Pathway#P04393>AP1#P04560;Gonadotropin-releasing hormone receptor pathway#P06664>JUN#P06757;B cell activation#P00010>jun#P00401;FAS signaling pathway#P00020>c-Jun#P00601;Gonadotropin-releasing hormone receptor pathway#P06664>Junc#P06710;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;PDGF signaling pathway#P00047>c-Jun#P01163;Huntington disease#P00029>c-Jun#P00776;CCKR signaling map#P06959>JUN#G06983;Gonadotropin-releasing hormone receptor pathway#P06664>Junc#G06677;Toll receptor signaling pathway#P00054>AP1#P01355;CCKR signaling map#P06959>JUN#P07114;Apoptosis signaling pathway#P00006>c-Jun#P00303;Oxidative stress response#P00046>c-jun#P01132;Gonadotropin-releasing hormone receptor pathway#P06664>Junc#G06891 LEPOC|Ensembl=ENSLOCG00000008969.1|UniProtKB=W5MRC9 W5MRC9 PTHR11751:SF308 ALANINE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE 1 transferase#PC00220;transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000006437.1|UniProtKB=W5MHB5 W5MHB5 PTHR14402:SF20 RECEPTOR TRANSPORTING PROTEIN RECEPTOR (CHEMOSENSORY) TRANSPORTER PROTEIN 3 GENE D [PROVISIONAL] binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 protein targeting#GO:0006605;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;intracellular protein localization#GO:0008104;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016788.1|UniProtKB=W5NJE3 W5NJE3 PTHR24323:SF8 CEH-10 HOMEODOMAIN-CONTAINING HOMOLOG VISUAL SYSTEM HOMEOBOX 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009325.1|UniProtKB=W5MSM2 W5MSM2 PTHR35971:SF5 SI:DKEY-31G6.6 OBSCURIN LIKE CYTOSKELETAL ADAPTOR 1 LEPOC|Ensembl=ENSLOCG00000011232.1|UniProtKB=W5MZK2 W5MZK2 PTHR11849:SF196 ETS ETS TRANSLOCATION VARIANT 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006399.1|UniProtKB=W5MH69 W5MH69 PTHR22842:SF3 WD40 REPEAT PROTEIN WD REPEAT DOMAIN-CONTAINING PROTEIN 83 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 LEPOC|Ensembl=ENSLOCG00000017774.1|UniProtKB=W5NML9 W5NML9 PTHR24237:SF7 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183 sterol binding#GO:0032934;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;G protein-coupled receptor activity#GO:0004930;steroid binding#GO:0005496;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;B cell activation involved in immune response#GO:0002312;cell activation involved in immune response#GO:0002263;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;response to stimulus#GO:0050896;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;positive regulation of leukocyte activation#GO:0002696;regulation of B cell proliferation#GO:0030888;B cell activation#GO:0042113;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;lymphocyte activation involved in immune response#GO:0002285;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of immune system process#GO:0002684;regulation of B cell activation#GO:0050864;regulation of multicellular organismal process#GO:0051239;taxis#GO:0042330;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;positive regulation of lymphocyte proliferation#GO:0050671;chemotaxis#GO:0006935;cell activation#GO:0001775;cell chemotaxis#GO:0060326;positive regulation of lymphocyte activation#GO:0051251;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;positive regulation of B cell proliferation#GO:0030890;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of immune system process#GO:0002682;positive regulation of leukocyte proliferation#GO:0070665;leukocyte migration#GO:0050900;response to external stimulus#GO:0009605;leukocyte chemotaxis#GO:0030595;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;regulation of lymphocyte proliferation#GO:0050670;cell migration#GO:0016477;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000303.1|UniProtKB=W5LW23 W5LW23 PTHR18884:SF128 SEPTIN SI:CH211-282J17.13-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104;cytokinesis#GO:0000910;cell cycle#GO:0007049;macromolecule localization#GO:0033036;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006637.1|UniProtKB=W5MI11 W5MI11 PTHR43806:SF7 PEPTIDASE S8 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-1 PROTEASE catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000001486.1|UniProtKB=W5M003 W5M003 PTHR11010:SF107 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED DIPEPTIDYL PEPTIDASE 2 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;lysosome#GO:0005764 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000001940.1|UniProtKB=W5M1I7 W5M1I7 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000000075.1|UniProtKB=W5LVC7 W5LVC7 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000012722.1|UniProtKB=W5N4V0 W5N4V0 PTHR10867:SF18 NNMT/PNMT/TEMT FAMILY MEMBER PHENYLETHANOLAMINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 LEPOC|Ensembl=ENSLOCG00000010520.1|UniProtKB=W5MWZ1 W5MWZ1 PTHR12552:SF4 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 26 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174;Integrin signalling pathway#P00034>GRAF#P00926 LEPOC|Ensembl=ENSLOCG00000016082.1|UniProtKB=W5NGQ6 W5NGQ6 PTHR24050:SF24 PA14 DOMAIN-CONTAINING PROTEIN EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000004965.1|UniProtKB=W5MC59 W5MC59 PTHR21340:SF0 DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL] hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787 nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside triphosphate biosynthetic process#GO:0009145;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015022.1|UniProtKB=W5NCY7 W5NCY7 PTHR10110:SF89 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 2 antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000008702.1|UniProtKB=W5MQE4 W5MQE4 PTHR11139:SF1 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;cellular response to stress#GO:0033554;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338 protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;SAGA complex#GO:0000124;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016671.1|UniProtKB=W5NIY5 W5NIY5 PTHR11486:SF69 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 23 fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102 multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000017854.1|UniProtKB=W5NMU8 W5NMU8 PTHR11929:SF10 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE 9 alpha-(1->3)-fucosyltransferase activity#GO:0046920;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000017160.1|UniProtKB=W5NKQ2 W5NKQ2 PTHR28598:SF1 STAGA COMPLEX 65 SUBUNIT GAMMA STAGA COMPLEX 65 SUBUNIT GAMMA transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 LEPOC|Ensembl=ENSLOCG00000003878.1|UniProtKB=W5M8D0 W5M8D0 PTHR24230:SF31 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 1 neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015296.1|UniProtKB=W5NDV8 W5NDV8 PTHR24117:SF6 AGAP007537-PB BCL-6 COREPRESSOR-LIKE PROTEIN 1 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000005015.1|UniProtKB=W5MCD1 W5MCD1 PTHR43829:SF7 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-3 water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;carbohydrate transmembrane transporter activity#GO:0015144 transport#GO:0006810;carbohydrate transport#GO:0008643;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;water transport#GO:0006833;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;fluid transport#GO:0042044;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219 membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002777.1|UniProtKB=W5M4L5 W5M4L5 PTHR13872:SF43 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein modification process#GO:0036211;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;post-translational protein modification#GO:0043687;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000012345.1|UniProtKB=W5N3I8 W5N3I8 PTHR24271:SF96 KALLIKREIN-RELATED GRANZYME A-RELATED catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000011459.1|UniProtKB=W5N0B8 W5N0B8 PTHR46845:SF2 INSULIN-LIKE GROWTH FACTOR I INSULIN-LIKE GROWTH FACTOR 3 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;binding#GO:0005488;signaling receptor binding#GO:0005102 positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;insulin-like growth factor receptor signaling pathway#GO:0048009;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell population proliferation#GO:0008283;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000011117.1|UniProtKB=W5MZ68 W5MZ68 PTHR13817:SF16 TITIN MYOMESIN-1 protein binding#GO:0005515;structural molecule activity#GO:0005198;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell differentiation#GO:0030154;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;A band#GO:0031672;contractile muscle fiber#GO:0043292;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;M band#GO:0031430;intracellular organelle#GO:0043229 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000003146.1|UniProtKB=W5M5Q4 W5M5Q4 QTRT2 PTHR46064:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000008355.1|UniProtKB=W5MP55 W5MP55 PTHR24092:SF81 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VA lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;intramembrane lipid carrier activity#GO:0140303 regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;phospholipid transport#GO:0015914;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006333.1|UniProtKB=W5MGY8 W5MGY8 PTHR19960:SF7 TEKTIN TEKTIN cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;organelle assembly#GO:0070925;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;cell motility#GO:0048870;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000010557.1|UniProtKB=W5MX35 W5MX35 PTHR11941:SF44 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011208.1|UniProtKB=W5MZH1 W5MZH1 PTHR45688:SF1 FAMILY NOT NAMED ETHANOLAMINE-PHOSPHATE PHOSPHO-LYASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000011008.1|UniProtKB=W5MYP4 W5MYP4 PTHR24327:SF26 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;skeletal system development#GO:0001501;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000004057.1|UniProtKB=W5M902 W5M902 PTHR13581:SF5 MRG-BINDING PROTEIN MRG_MORF4L-BINDING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000016271.1|UniProtKB=W5NHF8 W5NHF8 PTHR14869:SF0 MYC TARGET PROTEIN 1 MYC TARGET PROTEIN 1 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015465.1|UniProtKB=W5NEH3 W5NEH3 PTHR43394:SF29 ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL regulation of hemopoiesis#GO:1903706;porphyrin-containing compound biosynthetic process#GO:0006779;regulation of myeloid cell differentiation#GO:0045637;tetrapyrrole metabolic process#GO:0033013;tetrapyrrole biosynthetic process#GO:0033014;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of developmental process#GO:0050793;heme biosynthetic process#GO:0006783;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;metabolic process#GO:0008152;positive regulation of developmental process#GO:0051094;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;biological regulation#GO:0065007;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;regulation of multicellular organismal process#GO:0051239;pigment metabolic process#GO:0042440;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cell development#GO:0060284;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000016441.1|UniProtKB=W5NI47 W5NI47 PTHR31770:SF1 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-2 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chemokine#PC00074;cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000009337.1|UniProtKB=W5MSN0 W5MSN0 PTHR15317:SF1 T-CELL SURFACE PROTEIN TACTILE T-CELL SURFACE PROTEIN TACTILE cellular process#GO:0009987;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009136.1|UniProtKB=W5MRX8 W5MRX8 PTHR11949:SF50 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000011634.1|UniProtKB=W5N0Y5 W5N0Y5 PTHR31214:SF2 PROTEIN FAM221A-RELATED PROTEIN FAM221A LEPOC|Ensembl=ENSLOCG00000001989.1|UniProtKB=W5M1U6 W5M1U6 PTHR22988:SF73 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE-RELATED catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;actomyosin structure organization#GO:0031032;cytokinesis#GO:0000910;Rho protein signal transduction#GO:0007266;cytoskeleton-dependent cytokinesis#GO:0061640;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;embryo development#GO:0009790;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;cell division#GO:0051301;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;cortical cytoskeleton organization#GO:0030865;regulation of cell junction assembly#GO:1901888;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;cortical actin cytoskeleton organization#GO:0030866;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;multicellular organismal process#GO:0032501;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;mitotic cell cycle process#GO:1903047 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519 LEPOC|Ensembl=ENSLOCG00000015071.1|UniProtKB=W5ND37 W5ND37 PTHR10822:SF4 GLYPICAN GLYPICAN-3 regulation of response to stimulus#GO:0048583;regulation of localization#GO:0032879;positive regulation of canonical Wnt signaling pathway#GO:0090263;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of protein localization to membrane#GO:1905475;regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell migration#GO:0016477;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of protein localization#GO:0032880;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009174.1|UniProtKB=W5MS31 W5MS31 PTHR21552:SF2 ADULT RETINA PROTEIN CREB3 REGULATORY FACTOR DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000009915.1|UniProtKB=W5MUR2 W5MUR2 PTHR16172:SF43 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6 immune system process#GO:0002376;antigen processing and presentation#GO:0019882 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001415.1|UniProtKB=W5LZQ2 W5LZQ2 PTHR10462:SF51 GLYCOSYLTRANSFERASE-RELATED GLOBOSIDE ALPHA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1-LIKE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 vesicle#GO:0031982;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000002135.1|UniProtKB=W5M283 W5M283 PTHR34930:SF5 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 2 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017514.1|UniProtKB=W5NLW0 W5NLW0 PTHR31463:SF5 MACROPHAGE-EXPRESSED GENE 1 PROTEIN MACPF DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016142.1|UniProtKB=W5NGY0 W5NGY0 PTHR13546:SF13 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85A LEPOC|Ensembl=ENSLOCG00000012985.1|UniProtKB=W5N5T1 W5N5T1 PTHR16155:SF20 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-RELATED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000018263.1|UniProtKB=W5NP05 W5NP05 PTHR13538:SF4 N-ACETYLTRANSFERASE 6 N-ALPHA-ACETYLTRANSFERASE 80 ion binding#GO:0043167;acyltransferase activity#GO:0016746;anion binding#GO:0043168;small molecule binding#GO:0036094;N-acetyltransferase activity#GO:0008080;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;nucleoside phosphate binding#GO:1901265;acetyltransferase activity#GO:0016407;binding#GO:0005488;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;heterocyclic compound binding#GO:1901363;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212 regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000012725.1|UniProtKB=W5N4U9 W5N4U9 PTHR47966:SF26 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CATHEPSIN E catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;antigen processing and presentation#GO:0019882;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;immune system process#GO:0002376 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 aspartic protease#PC00053;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016176.1|UniProtKB=W5NH24 W5NH24 PTHR11419:SF1 INTERFERON GAMMA INTERFERON GAMMA-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 immune response#GO:0006955;multicellular organismal process#GO:0032501;adaptive immune response#GO:0002250;response to other organism#GO:0051707;biological regulation#GO:0065007;macrophage activation#GO:0042116;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cytokine-mediated signaling pathway#GO:0019221;cell activation#GO:0001775;cell communication#GO:0007154;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;response to type II interferon#GO:0034341;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;response to chemical#GO:0042221;myeloid leukocyte activation#GO:0002274;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;immune system process#GO:0002376;response to peptide#GO:1901652 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;cytokine#PC00083;interferon superfamily#PC00127 LEPOC|Ensembl=ENSLOCG00000003117.1|UniProtKB=W5M5N5 W5M5N5 PTHR10408:SF7 STEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;neutral lipid metabolic process#GO:0006638;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;acyltransferase#PC00042 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 LEPOC|Ensembl=ENSLOCG00000017806.1|UniProtKB=W5NMQ1 W5NMQ1 PTHR12974:SF34 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5C nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;positive regulation of biosynthetic process#GO:0009891;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604 LEPOC|Ensembl=ENSLOCG00000002057.1|UniProtKB=W5M1Y3 W5M1Y3 PTHR11088:SF89 TRNA DIMETHYLALLYLTRANSFERASE TRNA DIMETHYLALLYLTRANSFERASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000013337.1|UniProtKB=W5N732 W5N732 PTHR45701:SF5 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 2 binding#GO:0005488;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905;protein binding#GO:0005515 localization#GO:0051179;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;vesicle fusion#GO:0006906;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024 cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Circadian clock system#P00015>per#G01499;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Synaptic vesicle trafficking#P05734>Synaptobrevin#P05779;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Circadian clock system#P00015>Per#P00504;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Circadian clock system#P00015>per#G01503 LEPOC|Ensembl=ENSLOCG00000010524.1|UniProtKB=W5MWY7 W5MWY7 PTHR23320:SF170 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 18-LIKE transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006676.1|UniProtKB=W5MI50 W5MI50 PTHR44755:SF13 NATRIURETIC PEPTIDE RECEPTOR 3-RELATED NATRIURETIC PEPTIDE RECEPTOR 3 hormone binding#GO:0042562;binding#GO:0005488;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017290.1|UniProtKB=W5NL81 W5NL81 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 14A ISOFORM X1-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017342.1|UniProtKB=W5NLD8 W5NLD8 PTHR48431:SF1 TRANSMEMBRANE PROTEIN 250 TRANSMEMBRANE PROTEIN 250 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000008437.1|UniProtKB=W5MPE9 W5MPE9 PTHR11309:SF45 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 2 signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434 LEPOC|Ensembl=ENSLOCG00000015574.1|UniProtKB=W5NEW4 W5NEW4 PTHR13861:SF2 VACUOLAR ATP SYNTHASE SUBUNIT F V-TYPE PROTON ATPASE SUBUNIT F cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000015817.1|UniProtKB=W5NFR5 W5NFR5 PTHR13228:SF3 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5 transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;COG complex#GO:0017119;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000013949.1|UniProtKB=W5N991 W5N991 PTHR12294:SF10 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 3, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;metal ion transport#GO:0030001;mitochondrial calcium ion homeostasis#GO:0051560;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801 mitochondrion#GO:0005739;calcium channel complex#GO:0034704;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;transporter complex#GO:1990351 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000013784.1|UniProtKB=W5N8P5 W5N8P5 PTHR12002:SF78 CLAUDIN CLAUDIN-7 cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000016646.1|UniProtKB=W5NIV4 W5NIV4 PTHR11727:SF13 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 2, MITOCHONDRIAL rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;transcription regulator activity#GO:0140110;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;mitochondrial gene expression#GO:0140053;rRNA processing#GO:0006364;mitochondrial RNA metabolic process#GO:0000959;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;methylation#GO:0032259;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008023.1|UniProtKB=W5MMY8 W5MMY8 PTHR23198:SF6 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96 structural constituent of nuclear pore#GO:0017056;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;nucleic acid binding#GO:0003676 telomere tethering at nuclear periphery#GO:0034398;cellular localization#GO:0051641;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular component organization#GO:0016043;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;chromosome localization#GO:0050000;organelle localization#GO:0051640;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;telomere localization#GO:0034397;RNA localization#GO:0006403;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013814.1|UniProtKB=W5N8S5 W5N8S5 PTHR11673:SF34 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-1 translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000009498.1|UniProtKB=W5MTA1 W5MTA1 PTHR22851:SF0 U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 13 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004817.1|UniProtKB=W5MBM4 W5MBM4 PTHR24215:SF1 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 3 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198 cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;heart process#GO:0003015;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;developmental process#GO:0032502;muscle contraction#GO:0006936;heart contraction#GO:0060047;system process#GO:0003008;cellular developmental process#GO:0048869;tissue development#GO:0009888;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;striated muscle contraction#GO:0006941;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;myofibril#GO:0030016;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;nucleus#GO:0005634;sarcomere#GO:0030017;membraneless organelle#GO:0043228;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000015867.1|UniProtKB=W5NFY5 W5NFY5 PTHR13280:SF14 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 1 cellular process#GO:0009987;localization within membrane#GO:0051668;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179 LEPOC|Ensembl=ENSLOCG00000013272.1|UniProtKB=W5N6X6 W5N6X6 PTHR19134:SF430 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE DELTA phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;synaptic membrane adhesion#GO:0099560;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;synapse organization#GO:0050808;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000012405.1|UniProtKB=W5N3R5 W5N3R5 PTHR11280:SF9 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE DEAMINASE 2 binding#GO:0005488;catalytic activity#GO:0003824;identical protein binding#GO:0042802;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;protein binding#GO:0005515 small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;amino sugar catabolic process#GO:0046348;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 isomerase#PC00135 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 LEPOC|Ensembl=ENSLOCG00000004099.1|UniProtKB=W5M936 W5M936 PTHR11818:SF6 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN S structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063;sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory system development#GO:0048880;multicellular organismal process#GO:0032501 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000012153.1|UniProtKB=W5N2U4 W5N2U4 PTHR16160:SF11 FERMITIN 2-RELATED FERMITIN FAMILY HOMOLOG 2 protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839 cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925 LEPOC|Ensembl=ENSLOCG00000000758.1|UniProtKB=W5LXI3 W5LXI3 PTHR16222:SF23 ADP-RIBOSYLGLYCOHYDROLASE INACTIVE ADP-RIBOSYLTRANSFERASE ARH2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013816.1|UniProtKB=W5N8S8 W5N8S8 PTHR15197:SF0 COILIN P80 COILIN RNA binding#GO:0003723;snRNA binding#GO:0017069;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006122.1|UniProtKB=W5MG91 W5MG91 PTHR23357:SF1 RENALASE RENALASE catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000014088.1|UniProtKB=W5N9Q0 W5N9Q0 PTHR28621:SF1 SELENOPROTEIN S SELENOPROTEIN S regulation of cellular process#GO:0050794;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;localization#GO:0051179;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;transport#GO:0006810;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of biological process#GO:0050789;response to unfolded protein#GO:0006986;protein transport#GO:0015031;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;establishment of protein localization#GO:0045184;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000003510.1|UniProtKB=W5M706 W5M706 PTHR24046:SF3 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 2 regulation of biological process#GO:0050789;muscle cell differentiation#GO:0042692;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;muscle cell development#GO:0055001;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;smoothened signaling pathway#GO:0007224;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000010971.1|UniProtKB=W5MYJ7 W5MYJ7 PTHR45938:SF7 ACP24A4-RELATED WAP, KAZAL, IMMUNOGLOBULIN, KUNITZ AND NTR DOMAIN-CONTAINING PROTEIN 2 cytokine binding#GO:0019955;molecular function regulator activity#GO:0098772;transforming growth factor beta binding#GO:0050431;signaling receptor regulator activity#GO:0030545;signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to transforming growth factor beta#GO:0071559 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000001187.1|UniProtKB=W5LYY0 W5LYY0 PTHR11949:SF26 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 9 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010397.1|UniProtKB=W5MWJ0 W5MWJ0 PTHR23382:SF1 MALATE DEHYDROGENASE MALATE DEHYDROGENASE 1B-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;pyridine-containing compound metabolic process#GO:0072524;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000013836.1|UniProtKB=W5N8V8 W5N8V8 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017194.1|UniProtKB=W5NKU2 W5NKU2 PTHR12479:SF5 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4A regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of membrane permeability#GO:0090559 lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;lysosomal membrane#GO:0005765;cytoplasm#GO:0005737;vacuole#GO:0005773;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006764.1|UniProtKB=W5MIG5 W5MIG5 PTHR13271:SF164 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE SET DOMAIN-CONTAINING PROTEIN 4 histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;histone H3K4 methyltransferase activity#GO:0042800;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 chromatin remodeling#GO:0006338;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of response to external stimulus#GO:0032103;cellular component organization or biogenesis#GO:0071840;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of inflammatory response#GO:0050729;regulation of response to stress#GO:0080134 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 methyltransferase#PC00155;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007369.1|UniProtKB=W5MKM4 W5MKM4 PTHR19143:SF209 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 6 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000000907.1|UniProtKB=W5LY03 W5LY03 PTHR23115:SF271 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000015343.1|UniProtKB=W5NE23 W5NE23 PTHR15228:SF20 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 25 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 endocytosis#GO:0006897;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cytoskeleton organization#GO:0007010;negative regulation of signal transduction#GO:0009968;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;import into cell#GO:0098657;regulation of small GTPase mediated signal transduction#GO:0051056;membrane invagination#GO:0010324;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;localization#GO:0051179;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;membrane organization#GO:0061024;regulation of signal transduction#GO:0009966;establishment of localization#GO:0051234;actin filament organization#GO:0007015;negative regulation of cellular process#GO:0048523;phagocytosis#GO:0006909;transport#GO:0006810;regulation of response to stimulus#GO:0048583 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000015989.1|UniProtKB=W5NGC6 W5NGC6 PTHR13318:SF275 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 13 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000010329.1|UniProtKB=W5MWA0 W5MWA0 PTHR12957:SF23 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED INTEGRATOR COMPLEX SUBUNIT 6 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073 intracellular organelle#GO:0043229;integrator complex#GO:0032039;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000011353.1|UniProtKB=W5N006 W5N006 PTHR46514:SF2 AMPHIPHYSIN AMPHIPHYSIN lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle endocytosis#GO:0048488;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;synaptic vesicle recycling#GO:0036465;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular localization#GO:0051641;vesicle-mediated transport in synapse#GO:0099003;localization#GO:0051179 intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory vesicle#GO:0099503;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000014025.1|UniProtKB=W5N9I5 W5N9I5 PTHR16092:SF14 SEC3/SYNTAXIN-RELATED EXOCYST COMPLEX COMPONENT 1 phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546 Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization within membrane#GO:0051668;secretion by cell#GO:0032940;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893 plasma membrane#GO:0005886;exocyst#GO:0000145;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;membrane#GO:0016020;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015693.1|UniProtKB=W5NFA9 W5NFA9 PTHR28163:SF1 PROTEIN PET117 HOMOLOG, MITOCHONDRIAL PROTEIN PET117 HOMOLOG, MITOCHONDRIAL cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011373.1|UniProtKB=W5N030 W5N030 PTHR22948:SF14 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009338.1|UniProtKB=W5MSN3 W5MSN3 PTHR24188:SF29 ANKYRIN REPEAT PROTEIN GH09064P LEPOC|Ensembl=ENSLOCG00000009811.1|UniProtKB=W5MUD1 W5MUD1 PTHR15079:SF3 MYD88 MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;toll-like receptor 4 signaling pathway#GO:0034142;immune response-regulating cell surface receptor signaling pathway#GO:0002768;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to bacterium#GO:0009617;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;defense response to Gram-positive bacterium#GO:0050830;regulation of biological process#GO:0050789;immune system process#GO:0002376;defense response to bacterium#GO:0042742 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>MyD88#P01377;Toll pathway-drosophila#P06217>MyD88#P06346 LEPOC|Ensembl=ENSLOCG00000014922.1|UniProtKB=W5NCL4 W5NCL4 PTHR21623:SF2 SPERIOLIN-BINDING FACTOR COILED-COIL DOMAIN-CONTAINING PROTEIN 33 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000000971.1|UniProtKB=W5LY78 W5LY78 PTHR13999:SF38 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN IFITM3 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000009651.1|UniProtKB=W5MTT4 W5MTT4 PTHR11003:SF346 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 18 potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000004556.1|UniProtKB=W5MAN6 W5MAN6 PTHR24232:SF100 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 35.1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008502.1|UniProtKB=W5MPN6 W5MPN6 PTHR11418:SF0 GLUCAGON PRO-GLUCAGON signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 signal transduction#GO:0007165;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of insulin secretion#GO:0050796;chemical homeostasis#GO:0048878;regulation of transport#GO:0051049;regulation of localization#GO:0032879;glucose homeostasis#GO:0042593;positive regulation of protein secretion#GO:0050714;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;carbohydrate homeostasis#GO:0033500;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of protein transport#GO:0051223;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;intracellular glucose homeostasis#GO:0001678;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of hormone secretion#GO:0046883;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of carbohydrate metabolic process#GO:0006109;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;regulation of protein secretion#GO:0050708;homeostatic process#GO:0042592;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of hormone secretion#GO:0046887;regulation of establishment of protein localization#GO:0070201;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of secretion#GO:0051046 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 CCKR signaling map#P06959>GCG#G07291;CCKR signaling map#P06959>GCG#G06997 LEPOC|Ensembl=ENSLOCG00000018339.1|UniProtKB=W5NP81 W5NP81 PTHR15467:SF5 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004480.1|UniProtKB=W5MAE3 W5MAE3 PTHR10877:SF197 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-1-LIKE PROTEIN 2 ISOFORM X1 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to mechanical stimulus#GO:0009612;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;detection of mechanical stimulus#GO:0050982 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000010342.1|UniProtKB=W5MWC0 W5MWC0 PTHR23405:SF5 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED THO COMPLEX SUBUNIT 7 metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;transcription export complex#GO:0000346;intracellular organelle#GO:0043229;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000011438.1|UniProtKB=W5N0A4 W5N0A4 PTHR10539:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular protein-containing complex#GO:0140535;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634 protease#PC00190;protein modifying enzyme#PC00260 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Parkinson disease#P00049>19S proteasome#P01209 LEPOC|Ensembl=ENSLOCG00000010607.1|UniProtKB=W5MX84 W5MX84 PTHR16007:SF21 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45A LEPOC|Ensembl=ENSLOCG00000001320.1|UniProtKB=W5LZF4 W5LZF4 PTHR12411:SF1062 CYSTEINE PROTEASE FAMILY C1-RELATED SI:DKEY-158B13.1 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007936.1|UniProtKB=W5MMP7 W5MMP7 PTHR10989:SF19 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN-DEPENDENT TFPI-REGULATING PROTEIN catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;long-chain fatty acid metabolic process#GO:0001676;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 membrane raft#GO:0045121;membrane#GO:0016020;caveola#GO:0005901;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane microdomain#GO:0098857;plasma membrane raft#GO:0044853 LEPOC|Ensembl=ENSLOCG00000018048.1|UniProtKB=W5NNE0 W5NNE0 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015707.1|UniProtKB=W5NFE5 W5NFE5 PTHR15071:SF17 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR binding#GO:0005488;growth factor binding#GO:0019838;protein binding#GO:0005515 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;establishment of protein localization to vacuole#GO:0072666;protein localization to lysosome#GO:0061462;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;lysosomal transport#GO:0007041;protein localization to vacuole#GO:0072665 cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;late endosome#GO:0005770;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane traffic protein#PC00150 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Apoptosis signaling pathway#P00006>IGFR2#P00282;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895 LEPOC|Ensembl=ENSLOCG00000011038.1|UniProtKB=W5MYT4 W5MYT4 PTHR31322:SF2 E3 UBIQUITIN-PROTEIN LIGASE TM129 E3 UBIQUITIN-PROTEIN LIGASE TM129 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004655.1|UniProtKB=W5MB20 W5MB20 PTHR11739:SF8 CITRATE SYNTHASE CITRATE SYNTHASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Citrate Synthetase#P03141;TCA cycle#P00051>Citrate Synthase#P01267 LEPOC|Ensembl=ENSLOCG00000014935.1|UniProtKB=W5NCN0 W5NCN0 PTHR25462:SF309 BONUS, ISOFORM C-RELATED PML NUCLEAR BODY SCAFFOLD-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 cellular process#GO:0009987;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;defense response to other organism#GO:0098542;cellular response to stress#GO:0033554;immune system process#GO:0002376;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;defense response to virus#GO:0051607;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;DNA damage response#GO:0006974;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;apoptotic signaling pathway#GO:0097190;immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;response to virus#GO:0009615;cell communication#GO:0007154;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016262.1|UniProtKB=W5NHE9 W5NHE9 PTHR12581:SF0 HIV-1 REV BINDING PROTEIN 2, 3 KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011869.1|UniProtKB=W5N1T3 W5N1T3 PTHR12044:SF14 BCL2 INTERACTING MEDIATOR OF CELL DEATH MEIOTIC DOUBLE-STRANDED BREAK FORMATION PROTEIN 1 meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;reproductive process#GO:0022414;nuclear division#GO:0000280;meiotic cell cycle#GO:0051321;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;meiotic nuclear division#GO:0140013;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840 LEPOC|Ensembl=ENSLOCG00000016939.1|UniProtKB=W5NJY1 W5NJY1 PTHR18945:SF197 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-2 chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic signaling#GO:0099536;cellular process#GO:0009987;localization#GO:0051179;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 signaling receptor complex#GO:0043235;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;GABA-ergic synapse#GO:0098982 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000001714.1|UniProtKB=W5M0S4 W5M0S4 PTHR11785:SF536 AMINO ACID TRANSPORTER B(0,+)-TYPE AMINO ACID TRANSPORTER 1 amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;L-amino acid transmembrane transporter activity#GO:0015179 transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015557.1|UniProtKB=W5NEU0 W5NEU0 PTHR12316:SF26 NINJURIN-RELATED NINJURIN 2 cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515 programmed cell death#GO:0012501;response to stress#GO:0006950;cellular process#GO:0009987;cell death#GO:0008219;response to stimulus#GO:0050896;inflammatory response#GO:0006954;cell adhesion#GO:0007155;defense response#GO:0006952 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004087.1|UniProtKB=W5M921 W5M921 PTHR16470:SF0 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 LEPOC|Ensembl=ENSLOCG00000000293.1|UniProtKB=W5LW14 W5LW14 PTHR45786:SF74 DNA BINDING PROTEIN-LIKE ATP-DEPENDENT DNA HELICASE LEPOC|Ensembl=ENSLOCG00000016320.1|UniProtKB=W5NHP1 W5NHP1 PTHR24184:SF28 SI:CH211-189E2.2 ANKYRIN REPEAT AND SOCS BOX CONTAINING 3 cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000013309.1|UniProtKB=W5N704 W5N704 PTHR23180:SF197 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000003945.1|UniProtKB=W5M8K4 W5M8K4 PTHR24041:SF30 MUCIN EGF-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000006284.1|UniProtKB=W5MGS9 W5MGS9 PTHR10464:SF4 UREA TRANSPORTER UREA TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002242.1|UniProtKB=W5M2K2 W5M2K2 PTHR44888:SF2 HEPACAM FAMILY MEMBER 2-RELATED HEPATIC AND GLIAL CELL ADHESION MOLECULE LEPOC|Ensembl=ENSLOCG00000001937.1|UniProtKB=W5M1M2 W5M1M2 PTHR23280:SF15 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 5 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of cell adhesion#GO:0045785;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789 cell projection membrane#GO:0031253;ruffle#GO:0001726;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000016475.1|UniProtKB=W5NI93 W5NI93 PTHR46448:SF3 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN EXTRACELLULAR TYROSINE-PROTEIN KINASE PKDCC LEPOC|Ensembl=ENSLOCG00000016232.1|UniProtKB=W5NHA4 W5NHA4 PTHR23349:SF67 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 21 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000012031.1|UniProtKB=W5N2E0 W5N2E0 PTHR10159:SF309 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 1 catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anatomical structure formation involved in morphogenesis#GO:0048646;endoderm development#GO:0007492;regulation of MAPK cascade#GO:0043408;negative regulation of signal transduction#GO:0009968;endoderm formation#GO:0001706;embryo development#GO:0009790;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;formation of primary germ layer#GO:0001704;response to stimulus#GO:0050896;signaling#GO:0023052;gastrulation#GO:0007369;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131;Gonadotropin-releasing hormone receptor pathway#P06664>DUSP1#P06823;p38 MAPK pathway#P05918>MKP1#P05922 LEPOC|Ensembl=ENSLOCG00000015214.1|UniProtKB=W5NDL2 W5NDL2 PTHR15937:SF3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010107.1|UniProtKB=W5MVF9 W5MVF9 PTHR15177:SF2 G-PROTEIN COUPLED RECEPTOR 143 G PROTEIN-COUPLED RECEPTOR 143 signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;amino acid binding#GO:0016597;cation binding#GO:0043169;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;organic acid binding#GO:0043177;G protein-coupled peptide receptor activity#GO:0008528;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;neuropeptide receptor activity#GO:0008188 cellular pigmentation#GO:0033059;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;melanosome organization#GO:0032438;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell communication#GO:0007154;pigmentation#GO:0043473;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;melanosome#GO:0042470;plasma membrane#GO:0005886;apical part of cell#GO:0045177;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009945.1|UniProtKB=W5MUU9 W5MUU9 PTHR10155:SF7 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of receptor signaling pathway via JAK-STAT#GO:0046425;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of signaling#GO:0023051;cytokine-mediated signaling pathway#GO:0019221;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;response to peptide#GO:1901652;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 LEPOC|Ensembl=ENSLOCG00000009369.1|UniProtKB=W5MSS0 W5MSS0 PTHR10288:SF98 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002449.1|UniProtKB=W5M3C3 W5M3C3 PTHR10720:SF2 HEME OXYGENASE HEME OXYGENASE 2 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037 cellular process#GO:0009987;response to stress#GO:0006950;pigment metabolic process#GO:0042440;heme metabolic process#GO:0042168;catabolic process#GO:0009056;response to stimulus#GO:0050896;porphyrin-containing compound metabolic process#GO:0006778;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;response to oxidative stress#GO:0006979 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015668.1|UniProtKB=W5NF78 W5NF78 PTHR23231:SF17 GERM CELL-LESS PROTEIN GERM CELL-LESS 1, SPERMATOSIS ASSOCIATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001603.1|UniProtKB=W5M0E1 W5M0E1 PTHR13869:SF7 MYELIN P0 RELATED MYELIN PROTEIN P0 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731;myelination#GO:0042552;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell-cell adhesion#GO:0098609;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000004318.1|UniProtKB=W5M9W2 W5M9W2 PTHR12039:SF7 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 nucleotidyltransferase#PC00174;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000001611.1|UniProtKB=W5M0E4 W5M0E4 PTHR23339:SF65 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 2 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015818.1|UniProtKB=W5NFR4 W5NFR4 PTHR45476:SF4 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN 5 monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000007349.1|UniProtKB=W5MKK0 W5MKK0 PTHR12994:SF18 SECERNIN SECERNIN-3 LEPOC|Ensembl=ENSLOCG00000009061.1|UniProtKB=W5MRN9 W5MRN9 PTHR23180:SF402 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;system development#GO:0048731;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;organelle organization#GO:0006996;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neuron migration#GO:0001764;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;developmental process#GO:0032502;regulation of cell projection organization#GO:0031344 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000000125.1|UniProtKB=W5LVL6 W5LVL6 PTHR11412:SF81 MACROGLOBULIN / COMPLEMENT COMPLEMENT C3 molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;complement activation#GO:0006956;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;defense response to other organism#GO:0098542;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;humoral immune response#GO:0006959;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;immune system process#GO:0002376 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000017939.1|UniProtKB=W5NN33 W5NN33 PTHR23349:SF108 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BHLH DOMAIN-CONTAINING PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015364.1|UniProtKB=W5NE48 W5NE48 PTHR10625:SF43 HISTONE DEACETYLASE HDAC1-RELATED POLYAMINE DEACETYLASE HDAC10 deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000008186.1|UniProtKB=W5MNH9 W5MNH9 PTHR23320:SF129 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED TRANSMEMBRANE PROTEIN 176 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015467.1|UniProtKB=W5NEH7 W5NEH7 PTHR10829:SF5 CORTACTIN AND DREBRIN HEMATOPOIETIC LINEAGE CELL-SPECIFIC PROTEIN binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;cell migration#GO:0016477;regulation of actin filament polymerization#GO:0030833;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;actin filament#GO:0005884;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;membrane#GO:0016020;cell periphery#GO:0071944;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003181.1|UniProtKB=W5M5V3 W5M5V3 PTHR15104:SF0 DIHYDROPTERIDINE REDUCTASE DIHYDROPTERIDINE REDUCTASE catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000015926.1|UniProtKB=W5NG49 W5NG49 PTHR23284:SF0 PROLACTIN REGULATORY ELEMENT BINDING PROTEIN GUANINE NUCLEOTIDE-EXCHANGE FACTOR SEC12 cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;vesicle budding from membrane#GO:0006900;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000009655.1|UniProtKB=W5MTU0 W5MTU0 PTHR11037:SF17 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 2 HOMOLOG DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;brain development#GO:0007420;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;tube development#GO:0035295;head development#GO:0060322;nervous system development#GO:0007399;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development ending in birth or egg hatching#GO:0009792;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011275.1|UniProtKB=W5MZP5 W5MZP5 PTHR24328:SF1 HOMEOBOX PROTEIN MOX HOMEOBOX PROTEIN MOX-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011054.1|UniProtKB=W5MYW1 W5MYW1 PTHR12829:SF9 N6-ADENOSINE-METHYLTRANSFERASE N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000000547.1|UniProtKB=W5LWU6 W5LWU6 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006728.1|UniProtKB=W5MIE4 W5MIE4 PTHR44461:SF1 QUINONE OXIDOREDUCTASE-LIKE PROTEIN 1 FERRY ENDOSOMAL RAB5 EFFECTOR COMPLEX SUBUNIT 4 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002199.1|UniProtKB=W5M2F2 W5M2F2 PTHR24027:SF80 CADHERIN-23 CADHERIN-13 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell migration#GO:0016477;cell motility#GO:0048870;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000012694.1|UniProtKB=W5N4T1 W5N4T1 PTHR24416:SF137 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714 positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;multicellular organismal process#GO:0032501;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>EGFR#P00466;EGF receptor signaling pathway#P00018>EGFR#P00542 LEPOC|Ensembl=ENSLOCG00000013331.1|UniProtKB=W5N730 W5N730 PTHR45905:SF3 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA3 small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;transport#GO:0006810;Golgi vesicle transport#GO:0048193 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000004735.1|UniProtKB=W5MBC6 W5MBC6 PTHR31781:SF1 UNC80 PROTEIN UNC-80 HOMOLOG transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;regulation of system process#GO:0044057;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;homeostatic process#GO:0042592;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814 axon#GO:0030424;cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;sodium channel complex#GO:0034706;membrane protein complex#GO:0098796;membrane#GO:0016020;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000008150.1|UniProtKB=W5MNF4 W5MNF4 PTHR12295:SF29 FURRY-RELATED PROTEIN FURRY HOMOLOG generation of neurons#GO:0048699;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cellular process#GO:0009987;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cell division site#GO:0032153 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015062.1|UniProtKB=W5ND29 W5ND29 PTHR24068:SF24 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000016353.1|UniProtKB=W5NHU2 W5NHU2 PTHR18879:SF22 CENTROSOMAL PROTEIN OF 290 KDA CENTROSOMAL PROTEIN OF 290 KDA cell projection organization#GO:0030030;visual system development#GO:0150063;cellular component organization#GO:0016043;cilium assembly#GO:0060271;ciliary transition zone assembly#GO:1905349;anatomical structure development#GO:0048856;non-motile cilium assembly#GO:1905515;eye development#GO:0001654;cilium organization#GO:0044782;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;camera-type eye development#GO:0043010;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;sensory system development#GO:0048880;renal system development#GO:0072001;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;kidney development#GO:0001822;cellular process#GO:0009987;cell projection assembly#GO:0030031;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502 cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;centriolar satellite#GO:0034451;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000014520.1|UniProtKB=W5NB62 W5NB62 PTHR15919:SF1 DAPPER-RELATED DAPPER HOMOLOG 3 regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002279.1|UniProtKB=W5M2R2 W5M2R2 PTHR12245:SF5 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007246.1|UniProtKB=W5MK60 W5MK60 PTHR10845:SF245 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 16 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585 cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000001724.1|UniProtKB=W5M0T0 W5M0T0 PTHR12866:SF2 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 aminoacyltransferase activity#GO:0016755;ubiquitin-like protein conjugating enzyme activity#GO:0061650;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;autophagosome assembly#GO:0000045;organelle organization#GO:0006996;glycogen catabolic process#GO:0005980;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;carbohydrate catabolic process#GO:0016052;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;glycogen metabolic process#GO:0005977;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;polysaccharide catabolic process#GO:0000272;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001679.1|UniProtKB=W5M0Q0 W5M0Q0 PTHR11875:SF75 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 4 protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular component assembly#GO:0022607 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017686.1|UniProtKB=W5NMD2 W5NMD2 PTHR40472:SF11 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 3-RELATED LEPOC|Ensembl=ENSLOCG00000000943.1|UniProtKB=W5LY47 W5LY47 PTHR12941:SF13 ER MEMBRANE PROTEIN COMPLEX ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8 molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;EMC complex#GO:0072546;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000003059.1|UniProtKB=W5M5E4 W5M5E4 PTHR10903:SF112 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000008760.1|UniProtKB=W5MQJ9 W5MQJ9 PTHR24241:SF183 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TYPE II GNRH RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000003637.1|UniProtKB=W5M7F9 W5M7F9 PTHR35249:SF2 DYNEIN REGULATORY COMPLEX SUBUNIT 7 DYNEIN REGULATORY COMPLEX SUBUNIT 7 cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;sperm motility#GO:0097722;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017 cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000015368.1|UniProtKB=W5NE52 W5NE52 PTHR12114:SF1 PARVIN GAMMA-PARVIN protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;substrate adhesion-dependent cell spreading#GO:0034446;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;cellular component organization#GO:0016043;regulation of developmental process#GO:0050793;cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036;cell adhesion#GO:0007155;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;regulation of biological quality#GO:0065008;cell-substrate adhesion#GO:0031589 actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membraneless organelle#GO:0043228;cell junction#GO:0030054 actin or actin-binding cytoskeletal protein#PC00041;actin and actin related protein#PC00039 LEPOC|Ensembl=ENSLOCG00000009250.1|UniProtKB=W5MSC5 W5MSC5 PTHR19853:SF1 WD REPEAT CONTAINING PROTEIN 3 WDR3 TBC1 DOMAIN FAMILY MEMBER 31 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000010044.1|UniProtKB=W5MV77 W5MV77 PTHR46939:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000002312.1|UniProtKB=W5M2V3 W5M2V3 PTHR46676:SF1 PROTEIN AMBP PROTEIN AMBP enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000002391.1|UniProtKB=W5M368 W5M368 PTHR24257:SF19 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 2B catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;catabolic process#GO:0009056;protein catabolic process#GO:0030163;regulation of platelet aggregation#GO:0090330;regulation of platelet activation#GO:0010543;proteolysis#GO:0006508;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016622.1|UniProtKB=W5NIS6 W5NIS6 PTHR14897:SF5 WD REPEAT AND COILED-COIL-CONTAINING PROTEIN WD REPEAT AND COILED-COIL-CONTAINING PROTEIN protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899 LEPOC|Ensembl=ENSLOCG00000016454.1|UniProtKB=W5NI70 W5NI70 PTHR10865:SF6 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA3 histone deacetylase binding#GO:0042826;transcription coactivator activity#GO:0003713;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;protein binding#GO:0005515;binding#GO:0005488;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000002711.1|UniProtKB=W5M470 W5M470 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007751.1|UniProtKB=W5MM04 W5MM04 PTHR19863:SF5 NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG WD REPEAT-CONTAINING PROTEIN 47 LEPOC|Ensembl=ENSLOCG00000004521.1|UniProtKB=W5MAJ7 W5MAJ7 ADK PTHR45769:SF3 ADENOSINE KINASE ADENOSINE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;nucleoside kinase activity#GO:0019206;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 primary metabolic process#GO:0044238;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000010234.1|UniProtKB=W5MVX3 W5MVX3 PTHR11183:SF167 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN-2 glucosyltransferase activity#GO:0046527;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000017285.1|UniProtKB=W5NL74 W5NL74 PTHR18820:SF1 LEG1 PROTEIN LEG1 HOMOLOG extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001062.1|UniProtKB=W5LYI9 W5LYI9 PTHR15186:SF9 RE48077P ZGC:73226 macroautophagy#GO:0016236;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;autophagy#GO:0006914;positive regulation of cellular process#GO:0048522;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;catabolic process#GO:0009056;cellular component organization#GO:0016043;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000001895.1|UniProtKB=W5M1F0 W5M1F0 PTHR13831:SF0 MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS PROTEIN HIRA chromatin binding#GO:0003682;binding#GO:0005488;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005467.1|UniProtKB=W5MDY4 W5MDY4 PTHR10671:SF25 EPITHELIAL MEMBRANE PROTEIN-RELATED LENS INTRINSIC MEMBRANE PROTEIN 2.1-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000001316.1|UniProtKB=W5LZE4 W5LZE4 PTHR11849:SF171 ETS ETS HOMOLOGOUS FACTOR DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000008928.1|UniProtKB=W5MR62 W5MR62 PTHR14796:SF3 NEURENSIN 1-RELATED NEURENSIN 1-LIKE-RELATED multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;system development#GO:0048731;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;endomembrane system#GO:0012505;transport vesicle#GO:0030133;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell body#GO:0044297;vesicle#GO:0031982;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000003585.1|UniProtKB=W5M796 W5M796 PTHR43220:SF18 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41B catabolic process#GO:0009056;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;metabolic process#GO:0008152;organelle assembly#GO:0070925 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000003956.1|UniProtKB=W5M8M4 W5M8M4 PTHR15574:SF40 WD REPEAT DOMAIN-CONTAINING FAMILY WD AND TETRATRICOPEPTIDE REPEATS PROTEIN 1 regulation of lipid metabolic process#GO:0019216;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of lipid biosynthetic process#GO:0046890;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;biological regulation#GO:0065007 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004333.1|UniProtKB=W5M9X7 W5M9X7 PAN2 PTHR15728:SF0 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000015962.1|UniProtKB=W5NG94 W5NG94 PTHR24068:SF128 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 H acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000007233.1|UniProtKB=W5MK43 W5MK43 PTHR13651:SF1 PROTEIN ABITRAM PROTEIN ABITRAM protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin monomer binding#GO:0003785;binding#GO:0005488 neurogenesis#GO:0022008;regulation of filopodium assembly#GO:0051489;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;regulation of cell projection assembly#GO:0060491;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of supramolecular fiber organization#GO:1902903;dendrite morphogenesis#GO:0048813;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;neuron development#GO:0048666;regulation of biological quality#GO:0065008;dendrite development#GO:0016358;regulation of actin filament length#GO:0030832;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;cell projection organization#GO:0030030;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043 cell leading edge#GO:0031252;nucleus#GO:0005634;neuron projection#GO:0043005;lamellipodium#GO:0030027;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;dendrite#GO:0030425;filopodium#GO:0030175;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010062.1|UniProtKB=W5MV97 W5MV97 PTHR31095:SF3 RIKEN CDNA 9930021J03 GENE BROMODOMAIN CONTAINING 10 LEPOC|Ensembl=ENSLOCG00000011334.1|UniProtKB=W5MZX5 W5MZX5 PTHR10877:SF196 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2-LIKE PROTEIN 1 calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;cation binding#GO:0043169;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;small molecule binding#GO:0036094;ion binding#GO:0043167;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;calcium channel activity#GO:0005262;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;monoatomic ion-gated channel activity#GO:0022839;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;calcium-activated potassium channel activity#GO:0015269;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;metal ion binding#GO:0046872;protein binding#GO:0005515;gated channel activity#GO:0022836;calcium ion binding#GO:0005509;binding#GO:0005488;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;cytoskeletal protein binding#GO:0008092 detection of stimulus#GO:0051606;cellular process#GO:0009987;response to mechanical stimulus#GO:0009612;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;detection of mechanical stimulus#GO:0050982;transport#GO:0006810;establishment of localization#GO:0051234;response to external stimulus#GO:0009605;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000017341.1|UniProtKB=W5NLD7 W5NLD7 PTHR23048:SF30 MYOSIN LIGHT CHAIN 1, 3 CARDIAC MYOSIN LIGHT CHAIN-1-RELATED structural molecule activity#GO:0005198;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000009125.1|UniProtKB=W5MRW8 W5MRW8 PTHR10151:SF107 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 3 nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010190.1|UniProtKB=W5MVT0 W5MVT0 PTHR12106:SF9 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003432.1|UniProtKB=W5M6Q8 W5M6Q8 PTHR44324:SF1 WD40 REPEAT DOMAIN 95 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 337 LEPOC|Ensembl=ENSLOCG00000011337.1|UniProtKB=W5MZY2 W5MZY2 PTHR12616:SF1 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 catabolic process#GO:0009056;response to stimulus#GO:0050896;vesicle fusion#GO:0006906;response to starvation#GO:0042594;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;localization#GO:0051179;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;macroautophagy#GO:0016236;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;membrane fusion#GO:0061025;response to stress#GO:0006950;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;intracellular transport#GO:0046907;cellular response to nutrient levels#GO:0031669;vacuolar transport#GO:0007034;transport#GO:0006810 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle tethering complex#GO:0099023;vacuolar membrane#GO:0005774;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003794.1|UniProtKB=W5M823 W5M823 PTHR24356:SF449 SERINE/THREONINE-PROTEIN KINASE 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to peptide hormone stimulus#GO:0071375;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699 non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>PDK1/2#P04616;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PDK1#P00831;PI3 kinase pathway#P00048>P110ACT#P01177;Ras Pathway#P04393>PDK#P04555;Interleukin signaling pathway#P00036>PDK1/2#P00985;PI3 kinase pathway#P00048>PDK1#P01196;CCKR signaling map#P06959>PDPK1#P07162;PI3 kinase pathway#P00048>PDK1 ACT#P01190;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PDK1/2#P00903;PDGF signaling pathway#P00047>PDK1/2#P01164;p53 pathway feedback loops 2#P04398>PDK1/2#P04656 LEPOC|Ensembl=ENSLOCG00000011739.1|UniProtKB=W5N1C5 W5N1C5 PTHR31397:SF1 BLOC-1-RELATED COMPLEX SUBUNIT 7 BORSC7 BLOC-1-RELATED COMPLEX SUBUNIT 7 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000016010.1|UniProtKB=W5NGG1 W5NGG1 PTHR22069:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN S18 RADIAL SPOKE HEAD PROTEIN 9 HOMOLOG cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578 plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;axoneme#GO:0005930 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000008823.1|UniProtKB=W5MQS9 W5MQS9 PTHR43173:SF19 ABC1 FAMILY PROTEIN AARF DOMAIN-CONTAINING PROTEIN KINASE 1 cellular component organization#GO:0016043;lipid homeostasis#GO:0055088;organelle organization#GO:0006996;cellular process#GO:0009987;mitochondrion organization#GO:0007005;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840 mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000018060.1|UniProtKB=W5NNF2 W5NNF2 PTHR11937:SF606 ACTIN ACTIN-3-LIKE structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039 LEPOC|Ensembl=ENSLOCG00000005240.1|UniProtKB=W5MD52 W5MD52 PTHR11486:SF41 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 22 growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 system development#GO:0048731;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of cellular process#GO:0048522;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344 extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000016234.1|UniProtKB=W5NHA9 W5NHA9 PTHR24372:SF71 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE-RICH REPEAT-CONTAINING G PROTEIN-COUPLED RECEPTOR 5 molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;hormone-mediated signaling pathway#GO:0009755;positive regulation of signaling#GO:0023056;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to hormone#GO:0009725;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of Wnt signaling pathway#GO:0030177;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007851.1|UniProtKB=W5MMC6 W5MMC6 PTHR18934:SF88 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX32-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009849.1|UniProtKB=W5MUI4 W5MUI4 PTHR47980:SF22 LD44762P RAS-RELATED PROTEIN RAB-3B protein binding#GO:0005515;binding#GO:0005488;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092 secretion by cell#GO:0032940;exocytosis#GO:0006887;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 cell junction#GO:0030054;cell periphery#GO:0071944;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;endosome#GO:0005768;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000001960.1|UniProtKB=W5M1L0 W5M1L0 PTHR24103:SF700 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM7 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002630.1|UniProtKB=W5M409 W5M409 PTHR46046:SF2 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP9 LEPOC|Ensembl=ENSLOCG00000005160.1|UniProtKB=W5MCV0 W5MCV0 PTHR31296:SF1 UPF0565 PROTEIN C2ORF69 MITOCHONDRIAL PROTEIN C2ORF69 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000007857.1|UniProtKB=W5MMD8 W5MMD8 PTHR24092:SF50 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IIB-RELATED intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657 lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;endocytosis#GO:0006897;organophosphate ester transport#GO:0015748;transport#GO:0006810;Golgi vesicle transport#GO:0048193;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;macromolecule localization#GO:0033036;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;vesicle-mediated transport#GO:0016192;lipid transport#GO:0006869 cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000014608.1|UniProtKB=W5NBG5 W5NBG5 PTHR45834:SF6 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;postsynaptic specialization#GO:0099572;synapse#GO:0045202;cellular anatomical structure#GO:0110165;GABA-ergic synapse#GO:0098982;cytoplasm#GO:0005737;cytosol#GO:0005829;postsynapse#GO:0098794 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006571.1|UniProtKB=W5MHS6 W5MHS6 PTHR12451:SF0 TRANSCRIPTION FACTOR CASTOR PROTEIN MING -RELATED ZINC FINGER PROTEIN CASTOR HOMOLOG 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of neuron differentiation#GO:0045664;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000927.1|UniProtKB=W5LY31 W5LY31 PTHR12301:SF12 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM DOMAIN, SH3 DOMAIN AND NUCLEAR LOCALISATION SIGNALS 1A-RELATED regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;regulation of B cell activation#GO:0050864;negative regulation of cell activation#GO:0050866;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of lymphocyte activation#GO:0051249;regulation of cell communication#GO:0010646;negative regulation of multicellular organismal process#GO:0051241;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 LEPOC|Ensembl=ENSLOCG00000003969.1|UniProtKB=W5M8N1 W5M8N1 PTHR22599:SF12 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3C protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000002620.1|UniProtKB=W5M3X5 W5M3X5 PTHR16021:SF9 MANSC DOMAIN CONTAINING PROTEIN 1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001168.1|UniProtKB=W5LYV5 W5LYV5 PTHR23227:SF87 BUCENTAUR RELATED PROTEIN CFDP2 LEPOC|Ensembl=ENSLOCG00000003229.1|UniProtKB=W5M603 W5M603 PTHR20939:SF10 SORTING NEXIN 20, 21 SORTING NEXIN-21 phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005919.1|UniProtKB=W5MFJ0 W5MFJ0 PTHR24391:SF28 HISTONE H4 TRANSCRIPTION FACTOR-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000006262.1|UniProtKB=W5MGQ8 W5MGQ8 PTHR23142:SF1 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38A RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009687.1|UniProtKB=W5MTW9 W5MTW9 PTHR24028:SF253 CADHERIN-87A PROTOCADHERIN-7 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000008462.1|UniProtKB=W5MPI8 W5MPI8 PTHR14871:SF1 DYNEIN REGULATORY COMPLEX PROTEIN 9 DYNEIN REGULATORY COMPLEX PROTEIN 9 spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036 cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000007847.1|UniProtKB=W5MMB8 W5MMB8 PTHR31796:SF2 SUZ DOMAIN-CONTAINING PROTEIN 1 SUZ RNA-BINDING DOMAIN-CONTAINING LEPOC|Ensembl=ENSLOCG00000017240.1|UniProtKB=W5NL14 W5NL14 PTHR16089:SF19 REST COREPRESSOR COREST PROTEIN-RELATED TRANSCRIPTIONAL-REGULATING FACTOR 1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000011547.1|UniProtKB=W5N0P4 W5N0P4 PTHR13808:SF29 CBP/P300-RELATED HISTONE ACETYLTRANSFERASE P300 catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;chromatin DNA binding#GO:0031490;DNA binding#GO:0003677;histone acetyltransferase activity#GO:0004402;acyltransferase activity#GO:0016746;nucleic acid binding#GO:0003676;protein-lysine-acetyltransferase activity#GO:0061733;N-acetyltransferase activity#GO:0008080;chromatin binding#GO:0003682;transcription coactivator activity#GO:0003713;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;acetyltransferase activity#GO:0016407;binding#GO:0005488;transcription regulator activity#GO:0140110 positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007 chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;histone acetyltransferase complex#GO:0000123;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493 histone modifying enzyme#PC00261 Wnt signaling pathway#P00057>CBP#P01448;Huntington disease#P00029>CBP#P00777;p53 pathway#P00059>P300#P04611;Gonadotropin-releasing hormone receptor pathway#P06664>p300#P06737;p53 pathway#P00059>CBP#P04623;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Transcription regulation by bZIP transcription factor#P00055>CBP/P300#P01387 LEPOC|Ensembl=ENSLOCG00000014930.1|UniProtKB=W5NCM2 W5NCM2 PTHR24073:SF897 DRAB5-RELATED RAS-RELATED PROTEIN RAB pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791;mitochondrion#GO:0005739;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000012044.1|UniProtKB=W5N2G7 W5N2G7 PTHR13561:SF20 DNA REPLICATION REGULATOR DPB11-RELATED DNA TOPOISOMERASE 2-BINDING PROTEIN 1 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010758.1|UniProtKB=W5MXS5 W5MXS5 PTHR23179:SF28 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED RHO GTPASE-ACTIVATING PROTEIN 20 GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007156.1|UniProtKB=W5MJX0 W5MJX0 PTHR14240:SF6 RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN PROTEIN FANTOM ISOFORM X1 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929;ciliary transition zone#GO:0035869;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005031.1|UniProtKB=W5MCE8 W5MCE8 PTHR48034:SF5 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED COLD-INDUCIBLE RNA-BINDING PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005414.1|UniProtKB=W5MDS2 W5MDS2 PTHR24149:SF14 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000014569.1|UniProtKB=W5NBB8 W5NBB8 PTHR13116:SF11 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641 membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005307.1|UniProtKB=W5MDF1 W5MDF1 PTHR11690:SF304 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 1B ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010194.1|UniProtKB=W5MVS5 W5MVS5 PTHR10217:SF533 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED DELAYED RECTIFIER POTASSIUM CHANNEL KCNH5 voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000014852.1|UniProtKB=W5NCC8 W5NCC8 PTHR24241:SF69 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GONADOTROPIN-RELEASING HORMONE II RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000016389.1|UniProtKB=W5NHY3 W5NHY3 PTHR14237:SF103 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 nitrate metabolic process#GO:0042126;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000007732.1|UniProtKB=W5MLZ9 W5MLZ9 PTHR11036:SF11 SEMAPHORIN SEMAPHORIN-6C protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000016534.1|UniProtKB=W5NIG4 W5NIG4 PTHR24102:SF18 PHD FINGER PROTEIN PHD FINGER PROTEIN 21B LEPOC|Ensembl=ENSLOCG00000006476.1|UniProtKB=W5MHG4 W5MHG4 PTHR48026:SF31 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1-LIKE 3 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010091.1|UniProtKB=W5MVE2 W5MVE2 PTHR23345:SF9 VITELLOGENIN-RELATED VITELLOGENIN 2-RELATED molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 response to estradiol#GO:0032355;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to lipid#GO:0033993;response to oxygen-containing compound#GO:1901700 storage protein#PC00210 LEPOC|Ensembl=ENSLOCG00000009191.1|UniProtKB=W5MS52 W5MS52 PTHR31206:SF5 LP10445P PROTEIN FAM177A1 LEPOC|Ensembl=ENSLOCG00000000961.1|UniProtKB=W5LY67 W5LY67 PTHR10707:SF12 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 1, MITOCHONDRIAL cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775 cytochrome complex#GO:0070069;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle membrane#GO:0031090;transporter complex#GO:1990351 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007066.1|UniProtKB=W5MJJ6 W5MJJ6 PTHR22802:SF404 C-TYPE LECTIN SUPERFAMILY MEMBER SI:DKEY-9I23.4-RELATED signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;binding#GO:0005488 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004967.1|UniProtKB=W5MC64 W5MC64 PTHR24404:SF36 ZINC FINGER PROTEIN DNA-BINDING PROTEIN IKAROS sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012099.1|UniProtKB=W5N2N2 W5N2N2 PTHR47961:SF12 DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED HELICASE POLQ-LIKE ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678 response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;double-strand break repair via single-strand annealing#GO:0045002;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002180.1|UniProtKB=W5M2N3 W5M2N3 PTHR10048:SF15 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 phosphatidylinositol phosphate biosynthetic process#GO:0046854;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000009114.1|UniProtKB=W5MRV6 W5MRV6 PTHR11348:SF8 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 3 signaling receptor binding#GO:0005102;binding#GO:0005488;glycosaminoglycan binding#GO:0005539;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178 cartilage development#GO:0051216;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;skeletal system development#GO:0001501;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;connective tissue development#GO:0061448;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;biological regulation#GO:0065007;tissue development#GO:0009888;multicellular organismal process#GO:0032501;chondrocyte differentiation#GO:0002062;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007157.1|UniProtKB=W5MJV9 W5MJV9 PTHR46914:SF1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 response to biotic stimulus#GO:0009607;detection of stimulus#GO:0051606;response to stress#GO:0006950;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of apoptotic process#GO:0042981;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;inflammatory response#GO:0006954 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;canonical inflammasome complex#GO:0061702;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000014297.1|UniProtKB=W5NAE2 W5NAE2 PTHR18945:SF76 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-5 monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;acetylcholine receptor activity#GO:0015464;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 transport#GO:0006810;establishment of localization#GO:0051234;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;modulation of chemical synaptic transmission#GO:0050804;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;neuromuscular synaptic transmission#GO:0007274;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896 transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA5#P06593;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000014168.1|UniProtKB=W5N9Z4 W5N9Z4 PTHR24056:SF503 CELL DIVISION PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012901.1|UniProtKB=W5N5H9 W5N5H9 PTHR23235:SF48 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000003670.1|UniProtKB=W5M7L0 W5M7L0 PTHR14383:SF6 SWAP-70 RECOMBINASE SWITCH-ASSOCIATED PROTEIN 70 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005257.1|UniProtKB=W5MD70 W5MD70 PTHR24208:SF80 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>LHX2#P06756 LEPOC|Ensembl=ENSLOCG00000007842.1|UniProtKB=W5MMA7 W5MMA7 PTHR22624:SF36 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4D catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;proteolysis#GO:0006508;organelle assembly#GO:0070925;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;macromolecule metabolic process#GO:0043170;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;macroautophagy#GO:0016236;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;autophagosome organization#GO:1905037;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000002476.1|UniProtKB=W5M3E8 W5M3E8 PTHR17985:SF28 SER/THR-RICH PROTEIN T10 IN DGCR REGION TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG endomembrane system organization#GO:0010256;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;export from cell#GO:0140352;Golgi organization#GO:0007030;protein localization to extracellular region#GO:0071692;cellular component organization#GO:0016043;secretion by cell#GO:0032940;protein transport#GO:0015031;protein secretion#GO:0009306;localization#GO:0051179;secretion#GO:0046903 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000013262.1|UniProtKB=W5N6S7 W5N6S7 PTHR33767:SF1 LEUCINE RICH ADAPTOR PROTEIN 1-LIKE LEUCINE RICH ADAPTOR PROTEIN 1-LIKE biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 LEPOC|Ensembl=ENSLOCG00000003290.1|UniProtKB=W5M686 W5M686 PTHR11200:SF307 INOSITOL 5-PHOSPHATASE TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004051.1|UniProtKB=W5M8X3 W5M8X3 PTHR11455:SF18 CRYPTOCHROME DEOXYRIBODIPYRIMIDINE PHOTO-LYASE nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;nucleic acid binding#GO:0003676;deoxyribodipyrimidine photo-lyase activity#GO:0003904;small molecule binding#GO:0036094;anion binding#GO:0043168;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nucleotide binding#GO:0000166 response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;circadian regulation of gene expression#GO:0032922;response to abiotic stimulus#GO:0009628;circadian rhythm#GO:0007623;rhythmic process#GO:0048511;biological regulation#GO:0065007;regulation of circadian rhythm#GO:0042752;response to radiation#GO:0009314;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;photoperiodism#GO:0009648 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA photolyase#PC00014 Circadian clock system#P00015>Cry#P00505 LEPOC|Ensembl=ENSLOCG00000001150.1|UniProtKB=W5LZ04 W5LZ04 PTHR12546:SF44 FER-1-LIKE DYSFERLIN muscle cell development#GO:0055001;cellular component organization#GO:0016043;muscle cell differentiation#GO:0042692;cell differentiation#GO:0030154;response to stimulus#GO:0050896;muscle structure development#GO:0061061;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;plasma membrane organization#GO:0007009;anatomical structure development#GO:0048856;wound healing#GO:0042060;membrane fusion#GO:0061025;response to wounding#GO:0009611;response to stress#GO:0006950;cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869 intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000017009.1|UniProtKB=W5NK67 W5NK67 PTHR11579:SF7 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 methyltransferase#PC00155;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000006267.1|UniProtKB=W5MGR9 W5MGR9 PTHR13076:SF8 COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1A cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009273.1|UniProtKB=W5MSG1 W5MSG1 PTHR10887:SF433 DNA2/NAM7 HELICASE FAMILY DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2 DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788 replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA helicase#PC00032 DNA replication#P00017>Hel#P00532 LEPOC|Ensembl=ENSLOCG00000012050.1|UniProtKB=W5N2G5 W5N2G5 PTHR46388:SF2 NHL REPEAT-CONTAINING PROTEIN 2 NHL REPEAT-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000003302.1|UniProtKB=W5M6A3 W5M6A3 PTHR42698:SF1 GTPASE ERA GTPASE ERA, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;ribosomal small subunit biogenesis#GO:0042274;cellular component assembly#GO:0022607;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003 mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005070.1|UniProtKB=W5MCJ5 W5MCJ5 PTHR20914:SF24 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 LYMPHOCYTE ANTIGEN 6 FAMILY MEMBER M2-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006661.1|UniProtKB=W5MI35 W5MI35 PTHR21577:SF4 SHUGOSHIN SHUGOSHIN 1 nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;sister chromatid cohesion#GO:0007062;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;reproductive process#GO:0022414;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;meiotic nuclear division#GO:0140013;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;microtubule organizing center organization#GO:0031023;meiotic sister chromatid cohesion#GO:0051177;organelle organization#GO:0006996;cellular process#GO:0009987;mitotic sister chromatid cohesion#GO:0007064;cytoskeleton organization#GO:0007010 kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228 centromere DNA-binding protein#PC00071 LEPOC|Ensembl=ENSLOCG00000017230.1|UniProtKB=W5NL02 W5NL02 PTHR15629:SF46 SH3YL1 PROTEIN SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1 ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252;ruffle#GO:0001726;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000007080.1|UniProtKB=W5MJL1 W5MJL1 PTHR13773:SF16 PHOSPHATIDATE CYTIDYLYLTRANSFERASE PHOSPHATIDATE CYTIDYLYLTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organophosphate biosynthetic process#GO:0090407;organelle assembly#GO:0070925;lipid droplet organization#GO:0034389;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;organophosphate metabolic process#GO:0019637;organelle organization#GO:0006996;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid storage#GO:0019915;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000006487.1|UniProtKB=W5MHH4 W5MHH4 PTHR12277:SF52 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17A palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824 negative regulation of biological process#GO:0048519;regulation of postsynapse organization#GO:0099175;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of synapse organization#GO:0050807;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000011196.1|UniProtKB=W5MZE4 W5MZE4 PTHR12224:SF0 BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152;amino sugar metabolic process#GO:0006040 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007149.1|UniProtKB=W5MJU5 W5MJU5 PTHR12411:SF1058 CYSTEINE PROTEASE FAMILY C1-RELATED DIPEPTIDYL PEPTIDASE 1 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;extracellular region#GO:0005576;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013907.1|UniProtKB=W5N937 W5N937 PTHR14659:SF1 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000018149.1|UniProtKB=W5NNP1 W5NNP1 PTHR43895:SF26 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 LEPOC|Ensembl=ENSLOCG00000004865.1|UniProtKB=W5MBT5 W5MBT5 PTHR10489:SF931 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 3 protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine receptor activity#GO:0004896 response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;chemotaxis#GO:0006935;cell communication#GO:0007154;cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;locomotion#GO:0040011 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000548.1|UniProtKB=W5LWU8 W5LWU8 PTHR46711:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;histone H3K36 methyltransferase activity#GO:0046975;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000004916.1|UniProtKB=W5MC08 W5MC08 PTHR10064:SF2 60S RIBOSOMAL PROTEIN L22 LARGE RIBOSOMAL SUBUNIT PROTEIN EL22 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000002576.1|UniProtKB=W5M3R9 W5M3R9 PTHR22923:SF3 CEREBELLIN-RELATED CEREBELLIN-4 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017063.1|UniProtKB=W5NKC8 W5NKC8 PTHR42980:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;catalytic complex#GO:1902494;transferase complex#GO:1990234 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000006706.1|UniProtKB=W5MI94 W5MI94 PTHR16291:SF0 NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3 NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008064.1|UniProtKB=W5MN32 W5MN32 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001384.1|UniProtKB=W5LZM4 W5LZM4 PTHR11771:SF161 LIPOXYGENASE ARACHIDONATE 15-LIPOXYGENASE TYPE B catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;icosanoid metabolic process#GO:0006690;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;arachidonate metabolic process#GO:0019369 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014273.1|UniProtKB=W5NAB2 W5NAB2 PTHR23341:SF4 HIGH MOBILITY GROUP PROTEINS HMG-A AND C HIGH MOBILITY GROUP PROTEIN HMGI-C transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000002644.1|UniProtKB=W5M3Z6 W5M3Z6 PTHR10465:SF6 TRANSMEMBRANE GTPASE FZO1 SARCALUMENIN LEPOC|Ensembl=ENSLOCG00000010355.1|UniProtKB=W5MWE5 W5MWE5 PTHR24210:SF13 LIM DOMAIN-CONTAINING PROTEIN LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 1 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell junction organization#GO:0034330;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;cellular component organization#GO:0016043;positive regulation of signaling#GO:0023056;cell adhesion#GO:0007155;regulation of signaling#GO:0023051 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cytoplasm#GO:0005737;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 LEPOC|Ensembl=ENSLOCG00000003089.1|UniProtKB=W5M5H9 W5M5H9 PTHR15407:SF42 FUKUTIN-RELATED RIBITOL-5-PHOSPHATE TRANSFERASE FKTN biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000005635.1|UniProtKB=W5MEJ6 W5MEJ6 PTHR23350:SF0 PEROXISOME ASSEMBLY PROTEIN 10 PEROXISOME BIOGENESIS FACTOR 10 establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;peroxisomal transport#GO:0043574;protein transport#GO:0015031;peroxisome organization#GO:0007031;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012789.1|UniProtKB=W5N528 W5N528 PTHR14919:SF1 KPL2-RELATED SPERM FLAGELLA AND CILIA-ASSOCIATED PROTEIN 2 cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;sperm motility#GO:0097722;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000013057.1|UniProtKB=W5N619 W5N619 PTHR13809:SF28 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-T2 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;catalytic complex#GO:1902494 heterotrimeric G-protein#PC00117 5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Enkephalin release#P05913>G-Protein (s)#P05977;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;PI3 kinase pathway#P00048>Gbetagamma#P01188;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488 LEPOC|Ensembl=ENSLOCG00000002521.1|UniProtKB=W5M3K0 W5M3K0 PTHR46172:SF1 DNA POLYMERASE EPSILON SUBUNIT 3 DNA POLYMERASE EPSILON SUBUNIT 3 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;DNA binding#GO:0003677 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896 DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;ISWI-type complex#GO:0031010;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010288.1|UniProtKB=W5MW45 W5MW45 PTHR22939:SF14 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA3 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;proteolysis#GO:0006508;protein metabolic process#GO:0019538 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008167.1|UniProtKB=W5MNE9 W5MNE9 PTHR35287:SF1 SI:ZFOS-911D5.4 NERD DOMAIN-CONTAINING PROTEIN intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000013363.1|UniProtKB=W5N768 W5N768 PTHR22572:SF15 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE CATALYTIC SUBUNIT BETA nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;macromolecule metabolic process#GO:0043170;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleotide-sugar metabolic process#GO:0009225;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 LEPOC|Ensembl=ENSLOCG00000000703.1|UniProtKB=W5LXC3 W5LXC3 PTHR37557:SF4 115 KDA PROTEIN IN TYPE-1 RETROTRANSPOSABLE ELEMENT R1DM-LIKE PROTEIN-RELATED-RELATED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000015541.1|UniProtKB=W5NES1 W5NES1 PTHR48039:SF7 RNA-BINDING MOTIF PROTEIN 14B RNA-BINDING PROTEIN 28 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000000326.1|UniProtKB=W5LW52 W5LW52 PTHR23250:SF3 DYSFERLIN-RELATED FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000000260.1|UniProtKB=W5LVX8 W5LVX8 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED SI:DKEYP-69E1.8 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000002030.1|UniProtKB=W5M1U1 W5M1U1 PTHR24103:SF700 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM7 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007470.1|UniProtKB=W5ML10 W5ML10 PTHR11675:SF137 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000001222.1|UniProtKB=W5LZ26 W5LZ26 PTHR12197:SF184 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD HISTONE-LYSINE N-METHYLTRANSFERASE SMYD1 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;histone H3K4 methyltransferase activity#GO:0042800;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;heart development#GO:0007507;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;circulatory system development#GO:0072359 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000007090.1|UniProtKB=W5MJN0 W5MJN0 PTHR24351:SF171 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE BETA-2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;TOR signaling#GO:0031929;cell communication#GO:0007154;TORC1 signaling#GO:0038202;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 protein modifying enzyme#PC00260 PI3 kinase pathway#P00048>S6K#P01194;PDGF signaling pathway#P00047>p90RSK#P01142;p53 pathway by glucose deprivation#P04397>S6K#P04636;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 LEPOC|Ensembl=ENSLOCG00000011973.1|UniProtKB=W5N266 W5N266 PTHR24418:SF219 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE TEC protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000005264.1|UniProtKB=W5MD81 W5MD81 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-LIKE-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000014010.1|UniProtKB=W5N9F9 W5N9F9 PTHR14678:SF1 PROLINE-RICH PROTEIN 35-RELATED ZINC FINGER PROTEIN 750 transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;epidermis development#GO:0008544;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000014673.1|UniProtKB=W5NBQ6 W5NBQ6 PTHR10806:SF6 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane#GO:0016020;peptidase complex#GO:1905368;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 serine protease#PC00203 Vasopressin synthesis#P04395>Signal Peptidase#P04589;Endothelin signaling pathway#P00019>signal peptidase#P00573 LEPOC|Ensembl=ENSLOCG00000004912.1|UniProtKB=W5MC00 W5MC00 PTHR14555:SF1 MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED MELANOPHILIN protein binding#GO:0005515;binding#GO:0005488;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000000714.1|UniProtKB=W5LXD6 W5LXD6 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000005916.1|UniProtKB=W5MFI8 W5MFI8 PTHR10918:SF3 HOMER HOMER PROTEIN HOMOLOG 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cell surface receptor signaling pathway#GO:0007166;regulation of monoatomic ion transport#GO:0043269;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054 Metabotropic glutamate receptor group I pathway#P00041>Homer#P01058 LEPOC|Ensembl=ENSLOCG00000005679.1|UniProtKB=W5MEP7 W5MEP7 PTHR23235:SF19 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP7 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013737.1|UniProtKB=W5N8H9 W5N8H9 PTHR12137:SF60 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 13 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015153.1|UniProtKB=W5NDE7 W5NDE7 PTHR22845:SF5 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 FAS signaling pathway#P00020>Apaf1#P00597;Apoptosis signaling pathway#P00006>Apaf-1#P00301;Huntington disease#P00029>Apaf-1#P00768;p53 pathway#P00059>Apaf#G04703 LEPOC|Ensembl=ENSLOCG00000016685.1|UniProtKB=W5NJ04 W5NJ04 PTHR19143:SF466 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016563.1|UniProtKB=W5NIK3 W5NIK3 PTHR46237:SF2 CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER CYTOCHROME B5 REDUCTASE 4 catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987;superoxide metabolic process#GO:0006801 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000005305.1|UniProtKB=W5MDD8 W5MDD8 PTHR24304:SF6 CYTOCHROME P450 FAMILY 7 CHOLESTEROL 7-ALPHA-MONOOXYGENASE oxidoreductase activity#GO:0016491;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;cholesterol homeostasis#GO:0042632;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;small molecule metabolic process#GO:0044281;homeostatic process#GO:0042592;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;lipid homeostasis#GO:0055088;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000012697.1|UniProtKB=W5N4R7 W5N4R7 PTHR14492:SF4 JBTS17 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 1 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 ciliary transition zone#GO:0035869;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000009906.1|UniProtKB=W5MUP8 W5MUP8 PTHR19862:SF14 WD REPEAT-CONTAINING PROTEIN 48 WD REPEAT-CONTAINING PROTEIN 48 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950 LEPOC|Ensembl=ENSLOCG00000017413.1|UniProtKB=W5NLK9 W5NLK9 PTHR22237:SF2 APC MEMBRANE RECRUITMENT PROTEIN 2-RELATED APC MEMBRANE RECRUITMENT PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000017002.1|UniProtKB=W5NK57 W5NK57 PTHR45843:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015977.1|UniProtKB=W5NGB2 W5NGB2 PTHR10239:SF30 ISTHMIN-2 ISTHMIN-1 regulation of vasculature development#GO:1901342;regulation of angiogenesis#GO:0045765;negative regulation of angiogenesis#GO:0016525;regulation of anatomical structure morphogenesis#GO:0022603;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of multicellular organismal process#GO:0051239 LEPOC|Ensembl=ENSLOCG00000016449.1|UniProtKB=W5NI58 W5NI58 PTHR11630:SF107 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA HELICASE MCM8 DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000012066.1|UniProtKB=W5N2I8 W5N2I8 PTHR43730:SF1 BETA-MANNOSIDASE BETA-MANNOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004301.1|UniProtKB=W5M9S9 W5M9S9 PTHR19338:SF107 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 13 HOMOLOG MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM13 transport#GO:0006810;intracellular transport#GO:0046907;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrial protein import pathway#GO:7770058;membrane organization#GO:0061024;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;mitochondrial transport#GO:0006839 mitochondrial intermembrane space#GO:0005758;membrane-enclosed lumen#GO:0031974;mitochondrial envelope#GO:0005740;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000015034.1|UniProtKB=W5NCZ4 W5NCZ4 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002961.1|UniProtKB=W5M525 W5M525 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183-LIKE-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016730.1|UniProtKB=W5NJ67 W5NJ67 PTHR46079:SF3 FERM DOMAIN-CONTAINING PROTEIN 4 FERM DOMAIN-CONTAINING PROTEIN 4A apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell-cell junction#GO:0005911;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923 LEPOC|Ensembl=ENSLOCG00000011487.1|UniProtKB=W5N0F8 W5N0F8 PTHR12322:SF132 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX AND MAB-3-RELATED TRANSCRIPTION FACTOR 2A double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;sex differentiation#GO:0007548;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016452.1|UniProtKB=W5NI62 W5NI62 PTHR31746:SF3 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229B LEPOC|Ensembl=ENSLOCG00000012664.1|UniProtKB=W5N4M3 W5N4M3 PTHR44427:SF5 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000010181.1|UniProtKB=W5MVR0 W5MVR0 PTHR12419:SF21 OTU DOMAIN CONTAINING PROTEIN DEUBIQUITINASE OTUD6B catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000006937.1|UniProtKB=W5MJ32 W5MJ32 PTHR24229:SF107 NEUROPEPTIDES RECEPTOR KISS1 RECEPTOR transmembrane signaling receptor activity#GO:0004888;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;binding#GO:0005488;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003642.1|UniProtKB=W5M7G6 W5M7G6 PTHR15162:SF9 ASPARTOACYLASE ASPARTOACYLASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000003212.1|UniProtKB=W5M600 W5M600 PTHR22599:SF22 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3B enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000017349.1|UniProtKB=W5NLE5 W5NLE5 PTHR24394:SF18 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 18 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000014089.1|UniProtKB=W5N9Q5 W5N9Q5 PTHR11771:SF211 LIPOXYGENASE ARACHIDONATE 12-LIPOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 lipid oxidation#GO:0034440;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;arachidonate metabolic process#GO:0019369;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000000105.1|UniProtKB=W5LVH2 W5LVH2 PTHR10694:SF145 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4B catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;protein demethylase activity#GO:0140457;dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000001676.1|UniProtKB=W5M0R7 W5M0R7 PTHR45656:SF6 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 2 developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;postsynaptic density assembly#GO:0097107;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;postsynaptic density organization#GO:0097106;synapse organization#GO:0050808;anatomical structure development#GO:0048856;postsynaptic specialization organization#GO:0099084;system development#GO:0048731;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;synapse assembly#GO:0007416;cell junction organization#GO:0034330;excitatory synapse assembly#GO:1904861;postsynapse organization#GO:0099173 postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;membrane#GO:0016020;cell periphery#GO:0071944;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000008523.1|UniProtKB=W5MPR0 W5MPR0 PTHR16295:SF19 TRAF-TYPE ZINC FINGER PROTEIN-RELATED TRAF-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 negative regulation of innate immune response#GO:0045824;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of response to biotic stimulus#GO:0002831;negative regulation of defense response#GO:0031348;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of defense response#GO:0031347;negative regulation of immune response#GO:0050777;regulation of immune response#GO:0050776 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016179.1|UniProtKB=W5NH33 W5NH33 PTHR21625:SF1 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX PROTEIN 1 regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell projection organization#GO:0030030;regulation of microtubule-based movement#GO:0060632;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;axoneme assembly#GO:0035082;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium or flagellum-dependent cell motility#GO:0001539;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;plasma membrane bounded cell projection assembly#GO:0120031 ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012134.1|UniProtKB=W5N2R7 W5N2R7 PTHR45712:SF17 AGAP008170-PA ZGC:113307 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000012679.1|UniProtKB=W5N4N8 W5N4N8 PTHR10903:SF103 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER GIMD1 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000014204.1|UniProtKB=W5NA36 W5NA36 PTHR24028:SF123 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 4 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002749.1|UniProtKB=W5M4E4 W5M4E4 PTHR23077:SF27 AAA-FAMILY ATPASE ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000007761.1|UniProtKB=W5MM14 W5MM14 PTHR11921:SF47 SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000007991.1|UniProtKB=W5MMU6 W5MMU6 PTHR12117:SF0 HISTONE ACETYLTRANSFERASE COMPLEX PROLYL 3-HYDROXYLASE OGFOD1 dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein-containing complex disassembly#GO:0043244;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014399.1|UniProtKB=W5NAR5 W5NAR5 PTHR21192:SF2 NUCLEAR PROTEIN E3-3 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3 mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000013996.1|UniProtKB=W5N9E4 W5N9E4 PTHR13247:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11 MITOCHONDRIAL FISSION 1 PROTEIN lipid binding#GO:0008289;binding#GO:0005488 peroxisome organization#GO:0007031;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266 mitochondrion#GO:0005739;organelle envelope#GO:0031967;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;microbody#GO:0042579;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;peroxisomal membrane#GO:0005778;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 LEPOC|Ensembl=ENSLOCG00000010125.1|UniProtKB=W5MVI9 W5MVI9 PTHR20961:SF148 GLYCOSYLTRANSFERASE EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000001256.1|UniProtKB=W5LZ79 W5LZ79 PTHR11937:SF487 ACTIN ACTIN-LIKE PROTEIN 6A structural molecule activity#GO:0005198;chromatin binding#GO:0003682;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;nucleus#GO:0005634;chromatin#GO:0000785 actin and actin related protein#PC00039 LEPOC|Ensembl=ENSLOCG00000010169.1|UniProtKB=W5MVP0 W5MVP0 PTHR24031:SF25 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX46-RELATED nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000000989.1|UniProtKB=W5LYA7 W5LYA7 PTHR24403:SF48 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 10 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011458.1|UniProtKB=W5N0B9 W5N0B9 PTHR24168:SF19 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;negative regulation of cellular component organization#GO:0051129;cellular component organization#GO:0016043;negative regulation of organelle organization#GO:0010639;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;negative regulation of cytoskeleton organization#GO:0051494;regulation of biological quality#GO:0065008;negative regulation of protein-containing complex assembly#GO:0031333;regulation of actin filament length#GO:0030832;negative regulation of protein polymerization#GO:0032272 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000012944.1|UniProtKB=W5N5M8 W5N5M8 PTHR48168:SF1 RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED RNA GUANINE-N7 METHYLTRANSFERASE ACTIVATING SUBUNIT-RELATED enzyme regulator activity#GO:0030234;RNA binding#GO:0003723;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;binding#GO:0005488;nucleic acid binding#GO:0003676;enzyme activator activity#GO:0008047 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000014613.1|UniProtKB=W5NBH3 W5NBH3 PTHR24120:SF8 GH07239P ANKYRIN REPEAT AND SOCS BOX PROTEIN 12 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000012319.1|UniProtKB=W5N3F0 W5N3F0 PTHR11599:SF14 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-5 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000017552.1|UniProtKB=W5NLZ8 W5NLZ8 PTHR19290:SF172 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED ATONAL BHLH TRANSCRIPTION FACTOR 1A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;sensory organ development#GO:0007423;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000012741.1|UniProtKB=W5N4X5 W5N4X5 PTHR46121:SF2 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STAR-RELATED LIPID TRANSFER PROTEIN 3 alcohol binding#GO:0043178;steroid binding#GO:0005496;cholesterol binding#GO:0015485;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934 cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;sterol transport#GO:0015918;establishment of localization#GO:0051234;localization#GO:0051179 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle membrane contact site#GO:0044232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659 LEPOC|Ensembl=ENSLOCG00000015399.1|UniProtKB=W5NE90 W5NE90 PTHR11846:SF13 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;ligase#PC00142 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 LEPOC|Ensembl=ENSLOCG00000005043.1|UniProtKB=W5MCG3 W5MCG3 PTHR10174:SF72 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CLAVESIN-1 phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 lytic vacuole organization#GO:0080171;lysosome organization#GO:0007040;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840 Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000010668.1|UniProtKB=W5MXJ6 W5MXJ6 PTHR10037:SF304 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1D ISOFORM X1 sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;regulation of transport#GO:0051049;regulation of localization#GO:0032879;transport#GO:0006810;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;localization#GO:0051179;regulation of secretion#GO:0051046;monoatomic cation transport#GO:0006812;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;positive regulation of secretion#GO:0051047;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;action potential#GO:0001508 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;neuron projection#GO:0043005;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;sodium channel complex#GO:0034706;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000001573.1|UniProtKB=W5M090 W5M090 PTHR24072:SF24 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOE nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;actin filament-based process#GO:0030029;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948 LEPOC|Ensembl=ENSLOCG00000003412.1|UniProtKB=W5M6N1 W5M6N1 PTHR46374:SF2 PROTEIN CBG07384 STAR-RELATED LIPID TRANSFER PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000012114.1|UniProtKB=W5N2P5 W5N2P5 PTHR45682:SF5 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000010816.1|UniProtKB=W5MXZ2 W5MXZ2 PTHR46829:SF1 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15 molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 LEPOC|Ensembl=ENSLOCG00000010713.1|UniProtKB=W5MXL2 W5MXL2 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005490.1|UniProtKB=W5ME18 W5ME18 PTHR45636:SF19 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002031.1|UniProtKB=W5M1U3 W5M1U3 PTHR23055:SF84 CALCIUM BINDING PROTEINS HIPPOCALCIN-LIKE PROTEIN 4 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000015326.1|UniProtKB=W5NE02 W5NE02 PTHR11452:SF14 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-GALACTOSIDASE A hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 galactosidase#PC00104;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014602.1|UniProtKB=W5NBG3 W5NBG3 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011076.1|UniProtKB=W5MYY8 W5MYY8 PTHR44360:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012224.1|UniProtKB=W5N327 W5N327 PTHR46169:SF25 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 1 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000015597.1|UniProtKB=W5NEZ5 W5NEZ5 PTHR10844:SF18 CAVEOLIN CAVEOLIN-1 kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;transmembrane transporter binding#GO:0044325;enzyme binding#GO:0019899;protein binding#GO:0005515 monoatomic ion homeostasis#GO:0050801;negative regulation of cell population proliferation#GO:0008285;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;biological regulation#GO:0065007;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;negative regulation of cellular process#GO:0048523;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cytosolic calcium ion concentration#GO:0051480;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;plasma membrane organization#GO:0007009;regulation of cell population proliferation#GO:0042127 intracellular organelle#GO:0043229;plasma membrane raft#GO:0044853;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane raft#GO:0045121;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;Golgi apparatus#GO:0005794;membrane microdomain#GO:0098857;cell junction#GO:0030054;sarcolemma#GO:0042383;membrane#GO:0016020;caveola#GO:0005901;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>Caveolin-1#P06763;Integrin signalling pathway#P00034>Caveolin#P00918 LEPOC|Ensembl=ENSLOCG00000005445.1|UniProtKB=W5MDV4 W5MDV4 PTHR31101:SF2 UPF0547 PROTEIN C16ORF87 C16ORF87 HOMOLOG LEPOC|Ensembl=ENSLOCG00000017376.1|UniProtKB=W5NLH2 W5NLH2 PTHR24231:SF49 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 6-LIKE molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011638.1|UniProtKB=W5N0Y9 W5N0Y9 PTHR23105:SF101 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010855.1|UniProtKB=W5MY46 W5MY46 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009128.1|UniProtKB=W5MRW6 W5MRW6 PTHR12002:SF220 CLAUDIN CLAUDIN paracellular tight junction channel activity#GO:0160187;transporter activity#GO:0005215 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;establishment of localization#GO:0051234;localization#GO:0051179;paracellular transport#GO:0160184;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000010648.1|UniProtKB=W5MXD4 W5MXD4 PTHR13793:SF79 PHD FINGER PROTEINS PROTEIN JADE-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007933.1|UniProtKB=W5MMM5 W5MMM5 PTHR22792:SF166 LUPUS LA PROTEIN-RELATED LUPUS LA PROTEIN HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015675.1|UniProtKB=W5NF85 W5NF85 PTHR10201:SF340 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-21 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000005501.1|UniProtKB=W5ME29 W5ME29 PTHR12789:SF0 DENSITY-REGULATED PROTEIN HOMOLOG DENSITY-REGULATED PROTEIN binding#GO:0005488;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000002963.1|UniProtKB=W5M537 W5M537 PTHR10048:SF28 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT ALPHA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742 response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;cell motility#GO:0048870;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556;phosphatidylinositol phosphate biosynthetic process#GO:0046854;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;biological regulation#GO:0065007;biosynthetic process#GO:0009058;intracellular signaling cassette#GO:0141124;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 kinase#PC00137 FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;Integrin signalling pathway#P00034>PI3K#P00936;Axon guidance mediated by netrin#P00009>PI3K#P00363;VEGF signaling pathway#P00056>PI3K#P01413;Angiogenesis#P00005>PI3K#P00236;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;EGF receptor signaling pathway#P00018>PI3K#P00557 LEPOC|Ensembl=ENSLOCG00000009153.1|UniProtKB=W5MS04 W5MS04 PTHR46680:SF1 NF-KAPPA-B INHIBITOR ALPHA NF-KAPPA-B INHIBITOR ALPHA RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;binding#GO:0005488;transcription factor binding#GO:0008134;molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 regulation of cellular process#GO:0050794;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 T cell activation#P00053>I kappa B#P01323;B cell activation#P00010>I kappa B#P00392;Apoptosis signaling pathway#P00006>IkappaB#P00292;CCKR signaling map#P06959>IKBalpha#P07053;Toll receptor signaling pathway#P00054>IkappaB#P01338;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IkappaB#P00857 LEPOC|Ensembl=ENSLOCG00000008999.1|UniProtKB=W5MRF0 W5MRF0 PTHR15454:SF71 NISCHARIN RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016607.1|UniProtKB=W5NIQ5 W5NIQ5 PTHR12474:SF3 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;amino acid binding#GO:0016597;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;cation binding#GO:0043169;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;organic acid binding#GO:0043177 negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;positive regulation of macroautophagy#GO:0016239;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to chemical#GO:0042221;cellular response to amino acid starvation#GO:0034198;negative regulation of signal transduction#GO:0009968;negative regulation of TORC1 signaling#GO:1904262;regulation of macroautophagy#GO:0016241;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;response to nitrogen compound#GO:1901698;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;positive regulation of catabolic process#GO:0009896;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008654.1|UniProtKB=W5MQ64 W5MQ64 PTHR22802:SF475 C-TYPE LECTIN SUPERFAMILY MEMBER CD302 ANTIGEN molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014964.1|UniProtKB=W5NCR3 W5NCR3 PTHR45638:SF3 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ALPHA-2 guanyl nucleotide binding#GO:0019001;gated channel activity#GO:0022836;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;monoatomic ion channel activity#GO:0005216;purine ribonucleotide binding#GO:0032555;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;ligand-gated monoatomic ion channel activity#GO:0015276;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261 system process#GO:0003008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;sensory perception#GO:0007600;nervous system process#GO:0050877;transport#GO:0006810;sensory perception of chemical stimulus#GO:0007606;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;cellular process#GO:0009987 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000006388.1|UniProtKB=W5MH58 W5MH58 PTHR10177:SF70 CYCLINS G1_S-SPECIFIC CYCLIN-E2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 mitotic cell cycle phase transition#GO:0044772;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 kinase activator#PC00138 Parkinson disease#P00049>Cyclin E#P01213;Cell cycle#P00013>CdkC#P00489 LEPOC|Ensembl=ENSLOCG00000007418.1|UniProtKB=W5MKV5 W5MKV5 PTHR23122:SF39 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 7 protein localization to cell junction#GO:1902414;macromolecule localization#GO:0033036;localization#GO:0051179;intracellular protein localization#GO:0008104 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015297.1|UniProtKB=W5NDW2 W5NDW2 PTHR12955:SF1 SARCOMA ANTIGEN NY-SAR-95-RELATED INTEGRATOR COMPLEX SUBUNIT 13 localization#GO:0051179;biological regulation#GO:0065007;centrosome localization#GO:0051642;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;integrator complex#GO:0032039;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000017177.1|UniProtKB=W5NKS1 W5NKS1 PTHR11003:SF329 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL, SUBFAMILY K, MEMBER 17 voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010448.1|UniProtKB=W5MWP7 W5MWP7 PTHR14239:SF6 DUDULIN-RELATED METALLOREDUCTASE STEAP2 catalytic activity#GO:0003824;ferric-chelate reductase activity#GO:0000293;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722 monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transition metal ion transport#GO:0000041;transport#GO:0006810 membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000008555.1|UniProtKB=W5MPU6 W5MPU6 PTHR10117:SF25 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803 calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;metal ion transport#GO:0030001;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000005955.1|UniProtKB=W5MFN2 W5MFN2 PTHR15081:SF1 NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED NUCLEAR AUTOANTIGENIC SPERM PROTEIN binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;kinetochore organization#GO:0051383;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016028.1|UniProtKB=W5NGI5 W5NGI5 PTHR11202:SF11 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017450.1|UniProtKB=W5NLP6 W5NLP6 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN LOW QUALITY PROTEIN: ODORANT RECEPTOR 125-6-RELATED binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005506.1|UniProtKB=W5ME42 W5ME42 PTHR10445:SF0 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TFIIFbeta#P00667;Transcription regulation by bZIP transcription factor#P00055>TFIIFbeta#P01396 LEPOC|Ensembl=ENSLOCG00000003045.1|UniProtKB=W5M5C8 W5M5C8 PTHR12357:SF3 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING PROTEIN 1 mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;nucleic acid binding#GO:0003676;protein-RNA adaptor activity#GO:0140517;RNA binding#GO:0003723 mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008576.1|UniProtKB=W5MPX0 W5MPX0 PTHR21255:SF7 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002681.1|UniProtKB=W5M439 W5M439 PTHR24270:SF55 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR ISOFORM X1 anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;endocytosis#GO:0006897;central nervous system development#GO:0007417;establishment of localization#GO:0051234;import into cell#GO:0098657;multicellular organism development#GO:0007275;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;developmental process#GO:0032502;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987 membrane microdomain#GO:0098857;plasma membrane raft#GO:0044853;cell periphery#GO:0071944;membrane raft#GO:0045121;caveola#GO:0005901;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transfer/carrier protein#PC00219;apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000013747.1|UniProtKB=W5N8J5 W5N8J5 PTHR31158:SF1 DUAL OXIDASE 2 DUAL OXIDASE MATURATION FACTOR 2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000003869.1|UniProtKB=W5M8A8 W5M8A8 PTHR14614:SF5 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN EEF1A LYSINE METHYLTRANSFERASE 3 N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005232.1|UniProtKB=W5MD44 W5MD44 PTHR12035:SF107 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN MYELIN-ASSOCIATED GLYCOPROTEIN carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;carbohydrate derivative binding#GO:0097367;organic acid binding#GO:0043177 cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005909.1|UniProtKB=W5MFH7 W5MFH7 PTHR12960:SF0 GLE-1-RELATED MRNA EXPORT FACTOR GLE1 lipid binding#GO:0008289;protein binding#GO:0005515;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;alcohol binding#GO:0043178;translation initiation factor binding#GO:0031369;phospholipid binding#GO:0005543 nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000002861.1|UniProtKB=W5M4T0 W5M4T0 PTHR22922:SF3 GPI-ANCHORED PROTEIN P137 CAPRIN-1 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017011.1|UniProtKB=W5NK66 W5NK66 PTHR43827:SF14 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000004599.1|UniProtKB=W5MAV1 W5MAV1 PTHR10535:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;RNA polymerase I complex#GO:0005736;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 LEPOC|Ensembl=ENSLOCG00000016824.1|UniProtKB=W5NJJ3 W5NJJ3 PTHR11240:SF94 RIBONUCLEASE T2 RIBONUCLEASE T2 catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA catabolic process#GO:0006401;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000007201.1|UniProtKB=W5MK07 W5MK07 PTHR11422:SF6 T-CELL SURFACE GLYCOPROTEIN CD4 CD4-2 MOLECULE, TANDEM DUPLICATE 1 PRECURSOR-RELATED defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001308.1|UniProtKB=W5LZD2 W5LZD2 PTHR45848:SF4 DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000016837.1|UniProtKB=W5NJK0 W5NJK0 PTHR23235:SF65 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 11 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011672.1|UniProtKB=W5N139 W5N139 PTHR13239:SF7 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 STRIATIN-INTERACTING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;organelle organization#GO:0006996;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000000176.1|UniProtKB=W5LVN9 W5LVN9 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000005857.1|UniProtKB=W5MFB2 W5MFB2 PTHR18853:SF9 FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 27 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000017922.1|UniProtKB=W5NN16 W5NN16 PTHR46131:SF2 SD08549P MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER SLC25A51-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;purine nucleotide transmembrane transporter activity#GO:0015216;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015942.1|UniProtKB=W5NG69 W5NG69 PTHR24127:SF1 ANKYRIN REPEAT AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000005796.1|UniProtKB=W5MF59 W5MF59 PTHR11255:SF37 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 biosynthetic process#GO:0009058;biological regulation#GO:0065007;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;signal transduction#GO:0007165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;neutral lipid metabolic process#GO:0006638;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006276.1|UniProtKB=W5MGS1 W5MGS1 PTHR46222:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009298.1|UniProtKB=W5MSJ2 W5MSJ2 PTHR11690:SF252 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING (PROTON-GATED) ION CHANNEL 1C gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000010429.1|UniProtKB=W5MWM3 W5MWM3 PTHR12176:SF78 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE AND N-TERMINAL METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;lysine N-methyltransferase activity#GO:0016278 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012773.1|UniProtKB=W5N509 W5N509 PTHR48043:SF24 EG:EG0003.4 PROTEIN-RELATED UDP-GLYCOSYLTRANSFERASE 3A2 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020 cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 LEPOC|Ensembl=ENSLOCG00000016721.1|UniProtKB=W5NJ49 W5NJ49 PTHR24044:SF423 NOTCH LIGAND FAMILY MEMBER PROTEIN DELTA HOMOLOG 2 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013166.1|UniProtKB=W5N6G1 W5N6G1 PTHR19872:SF7 UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN F-BOX DOMAIN-CONTAINING PROTEIN ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008426.1|UniProtKB=W5MPE6 W5MPE6 PTHR13140:SF865 MYOSIN MYO1E PROTEIN microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 transport#GO:0006810;actin filament-based process#GO:0030029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;cytoskeleton organization#GO:0007010 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000009315.1|UniProtKB=W5MSK5 W5MSK5 PTHR12210:SF139 DULLARD PROTEIN PHOSPHATASE CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 1 protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000003797.1|UniProtKB=W5M822 W5M822 PTHR28591:SF1 LATEXIN LATEXIN peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000011130.1|UniProtKB=W5MZ70 W5MZ70 PTHR12231:SF231 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN NEURAL CELL ADHESION MOLECULE 2 protein binding#GO:0005515;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;axon development#GO:0061564;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell adhesion#GO:0007155;cell recognition#GO:0008037;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043 synaptic membrane#GO:0097060;cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005634.1|UniProtKB=W5MEK2 W5MEK2 PTHR10658:SF81 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PROTEIN RETINAL DEGENERATION B binding#GO:0005488;molecular carrier activity#GO:0140104;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylcholine intramembrane carrier activity#GO:0008525;lipid carrier activity#GO:0005319;ion binding#GO:0043167;cation binding#GO:0043169;intramembrane lipid carrier activity#GO:0140303;phospholipid binding#GO:0005543;phosphatidylinositol binding#GO:0035091;phosphatidylinositol transfer activity#GO:0008526;phosphatidylcholine binding#GO:0031210 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013329.1|UniProtKB=W5N725 W5N725 PTHR45747:SF18 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) HISTONE-LYSINE N-METHYLTRANSFERASE EZH2 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;binding#GO:0005488;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;chromatin binding#GO:0003682;N-methyltransferase activity#GO:0008170 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000009551.1|UniProtKB=W5MTG7 W5MTG7 PTHR12549:SF8 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE 3B nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;DNA binding#GO:0003677;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;histone demethylase activity#GO:0032452;chromatin DNA binding#GO:0031490;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000004570.1|UniProtKB=W5MAR6 W5MAR6 PTHR24145:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 11 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 11 anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856 LEPOC|Ensembl=ENSLOCG00000014190.1|UniProtKB=W5NA18 W5NA18 PTHR24366:SF35 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000002828.1|UniProtKB=W5M4S6 W5M4S6 PTHR47219:SF6 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE RAB GTPASE-ACTIVATING PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;binding#GO:0005488;enzyme binding#GO:0019899 GTPase-activating protein#PC00257;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000016131.1|UniProtKB=W5NGW7 W5NGW7 PTHR42909:SF1 ZGC:136858 CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007471.1|UniProtKB=W5ML12 W5ML12 PTHR11647:SF55 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;dihydropyrimidinase activity#GO:0004157;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812 pyrimidine nucleobase metabolic process#GO:0006206;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339 LEPOC|Ensembl=ENSLOCG00000009994.1|UniProtKB=W5MV11 W5MV11 PTHR11818:SF22 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN N structural molecule activity#GO:0005198 developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011966.1|UniProtKB=W5N255 W5N255 PTHR45689:SF3 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 1 transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789 somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009819.1|UniProtKB=W5MUD9 W5MUD9 PTHR18849:SF0 LEUCINE RICH REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410 LEPOC|Ensembl=ENSLOCG00000012194.1|UniProtKB=W5N2Z0 W5N2Z0 PTHR24369:SF238 ANTIGEN BSP, PUTATIVE-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011661.1|UniProtKB=W5N132 W5N132 PTHR23122:SF45 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PROTEIN PALS2 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006709.1|UniProtKB=W5MI97 W5MI97 UBE2C PTHR23399:SF2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;chromatin-protein adaptor activity#GO:0140463 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000005557.1|UniProtKB=W5MEA0 W5MEA0 PTHR13850:SF2 PLEIOTROPHIN FAMILY MEMBER MIDKINE molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001419.1|UniProtKB=W5LZR3 W5LZR3 PTHR45705:SF4 FI20236P1 STROMAL MEMBRANE-ASSOCIATED PROTEIN 2 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000007083.1|UniProtKB=W5MJL6 W5MJL6 PTHR23036:SF191 CYTOKINE RECEPTOR INTERLEUKIN-23 RECEPTOR ISOFORM X1 cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell population proliferation#GO:0008284;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017680.1|UniProtKB=W5NMC6 W5NMC6 PTHR15404:SF2 PROTEIN AF1Q PROTEIN AF1Q regulation of gene expression#GO:0010468;regulation of membrane potential#GO:0042391;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular component organization#GO:0051130;regulation of release of cytochrome c from mitochondria#GO:0090199;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of organelle organization#GO:0010638;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000010161.1|UniProtKB=W5MVN1 W5MVN1 PTHR24216:SF66 PAXILLIN-RELATED PAXILLIN protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;anchoring junction#GO:0070161 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000000810.1|UniProtKB=W5LXP5 W5LXP5 PTHR10751:SF1 GUANYLATE BINDING PROTEIN RING FINGER PROTEIN 112 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000006143.1|UniProtKB=W5MGB2 W5MGB2 PTHR13809:SF50 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 heterotrimeric G-protein#PC00117 LEPOC|Ensembl=ENSLOCG00000013462.1|UniProtKB=W5N7J2 W5N7J2 PTHR10908:SF4 SEROTONIN N-ACETYLTRANSFERASE SEROTONIN N-ACETYLTRANSFERASE acyltransferase activity#GO:0016746;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 rhythmic process#GO:0048511;photoperiodism#GO:0009648;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;circadian rhythm#GO:0007623;response to stimulus#GO:0050896;response to light stimulus#GO:0009416 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007196.1|UniProtKB=W5MK26 W5MK26 PTHR24223:SF241 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 oligopeptide transmembrane transporter activity#GO:0035673;tripeptide transmembrane transporter activity#GO:0042937;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;carboxylic acid transmembrane transporter activity#GO:0046943;ATPase-coupled transmembrane transporter activity#GO:0042626;xenobiotic transmembrane transporter activity#GO:0042910 transport#GO:0006810;xenobiotic transport#GO:0042908;oligopeptide transport#GO:0006857;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;oligopeptide transmembrane transport#GO:0035672;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000014069.1|UniProtKB=W5N9M9 W5N9M9 PTHR15549:SF37 PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR MID2 DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010590.1|UniProtKB=W5MX71 W5MX71 PTHR22957:SF260 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 8 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000013154.1|UniProtKB=W5N6E7 W5N6E7 PTHR33560:SF2 PROTEIN FAM227B PROTEIN FAM227B LEPOC|Ensembl=ENSLOCG00000012456.1|UniProtKB=W5N3X6 W5N3X6 PTHR22752:SF1 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 176 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004641.1|UniProtKB=W5MB02 W5MB02 PTHR21094:SF2 GOS-28 SNARE- RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle fusion#GO:0006906;intra-Golgi vesicle-mediated transport#GO:0006891;cellular component organization#GO:0016043;localization#GO:0051179 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;Golgi stack#GO:0005795;membrane protein complex#GO:0098796 SNARE protein#PC00034;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007909.1|UniProtKB=W5MMJ8 W5MMJ8 PTHR19961:SF27 FIMBRIN/PLASTIN PLASTIN-1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin binding#GO:0003779;actin filament binding#GO:0051015;molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092 actin filament bundle assembly#GO:0051017;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000008905.1|UniProtKB=W5MR39 W5MR39 PTHR11363:SF7 60S RIBOSOMAL PROTEIN L3-RELATED RIBOSOMAL PROTEIN UL3-LIKE RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000016223.1|UniProtKB=W5NHA7 W5NHA7 PTHR24348:SF64 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE DDB_G0278901-RELATED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000004399.1|UniProtKB=W5MA63 W5MA63 PTHR13140:SF353 MYOSIN UNCONVENTIONAL MYOSIN-IH cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based movement#GO:0030048;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;transport#GO:0006810;actin filament-based process#GO:0030029 plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000009953.1|UniProtKB=W5MUX2 W5MUX2 PTHR24040:SF18 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN GROWTH ARREST-SPECIFIC 6 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of intracellular signal transduction#GO:1902533;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007353.1|UniProtKB=W5MKK4 W5MKK4 PTHR24347:SF388 SERINE/THREONINE-PROTEIN KINASE DEATH-ASSOCIATED PROTEIN KINASE 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017516.1|UniProtKB=W5NLW2 W5NLW2 PTHR45640:SF36 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-6 negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;response to heat#GO:0009408;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;negative regulation of programmed cell death#GO:0043069;protein maturation#GO:0051604;gene expression#GO:0010467;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;protein folding#GO:0006457 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015980.1|UniProtKB=W5NGB7 W5NGB7 PTHR23073:SF13 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 7 isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;proteasome complex#GO:0000502;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000017072.1|UniProtKB=W5NKD9 W5NKD9 PTHR45955:SF5 PHOSPHOACETYLGLUCOSAMINE MUTASE PHOSPHOACETYLGLUCOSAMINE MUTASE intramolecular phosphotransferase activity#GO:0016868;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 UDP-N-acetylglucosamine biosynthetic process#GO:0006048;anatomical structure development#GO:0048856;UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cell development#GO:0048468;nucleoside phosphate metabolic process#GO:0006753;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;cell differentiation#GO:0030154;developmental process#GO:0032502;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular developmental process#GO:0048869;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;hemopoiesis#GO:0030097 isomerase#PC00135;mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000014248.1|UniProtKB=W5NAB3 W5NAB3 PTHR46399:SF10 B30.2/SPRY DOMAIN-CONTAINING PROTEIN RYANODINE RECEPTOR 1 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267 release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;multicellular organismal process#GO:0032501;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;muscle contraction#GO:0006936;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;system process#GO:0003008;calcium ion transmembrane transport#GO:0070588;muscle system process#GO:0003012;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;calcium channel complex#GO:0034704;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;sarcomere#GO:0030017;endoplasmic reticulum#GO:0005783;cation channel complex#GO:0034703;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;sarcoplasmic reticulum membrane#GO:0033017;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;sarcoplasmic reticulum#GO:0016529;contractile muscle fiber#GO:0043292;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;sarcolemma#GO:0042383;I band#GO:0031674;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;endomembrane system#GO:0012505;Z disc#GO:0030018;cell periphery#GO:0071944;membrane#GO:0016020 Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441;CCKR signaling map#P06959>RYR1/2/3#P07088 LEPOC|Ensembl=ENSLOCG00000007450.1|UniProtKB=W5MKX7 W5MKX7 PTHR18952:SF275 CARBONIC ANHYDRASE CARBONIC ANHYDRASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000011818.1|UniProtKB=W5N1N1 W5N1N1 PTHR23270:SF10 PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5 PROTEIN RRP5 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515;RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274 small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015242.1|UniProtKB=W5NDP6 W5NDP6 PTHR35075:SF1 A-KINASE ANCHOR PROTEIN 14 A-KINASE ANCHOR PROTEIN 14 protein kinase A regulatory subunit binding#GO:0034237;binding#GO:0005488;protein kinase A binding#GO:0051018;protein binding#GO:0005515 protein-containing complex#GO:0032991;serine/threonine protein kinase complex#GO:1902554;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006872.1|UniProtKB=W5MIY8 W5MIY8 PTHR23220:SF23 INTEGRIN ALPHA INTEGRIN ALPHA-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell surface receptor signaling pathway#GO:0007166;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863 LEPOC|Ensembl=ENSLOCG00000015027.1|UniProtKB=W5NCZ1 W5NCZ1 PTHR13778:SF2 GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN 2 glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009553.1|UniProtKB=W5MTH0 W5MTH0 PTHR10663:SF412 GUANYL-NUCLEOTIDE EXCHANGE FACTOR GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;Golgi organization#GO:0007030;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193 Golgi cis cisterna#GO:0000137;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi cisterna#GO:0031985;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000009390.1|UniProtKB=W5MSU6 W5MSU6 PTHR10835:SF0 SQUALENE MONOOXYGENASE SQUALENE MONOOXYGENASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxygenase#PC00177 Cholesterol biosynthesis#P00014>Squalene monooxygenas#P00494 LEPOC|Ensembl=ENSLOCG00000015990.1|UniProtKB=W5NGC8 W5NGC8 PTHR24366:SF123 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 17 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000004069.1|UniProtKB=W5M918 W5M918 PTHR19957:SF88 SYNTAXIN SYNTAXIN-12 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;cellular component organization#GO:0016043;vesicle organization#GO:0016050;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;vacuole organization#GO:0007033;localization#GO:0051179;organelle assembly#GO:0070925;vesicle fusion#GO:0006906;catabolic process#GO:0009056;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;membrane fusion#GO:0061025 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;recycling endosome#GO:0055037;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;synapse#GO:0045202;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;postsynapse#GO:0098794 SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 LEPOC|Ensembl=ENSLOCG00000013739.1|UniProtKB=W5N8I1 W5N8I1 PTHR45840:SF5 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 3 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 LEPOC|Ensembl=ENSLOCG00000012042.1|UniProtKB=W5N2F3 W5N2F3 PTHR47729:SF1 SERINE PEPTIDASE INHIBITOR, KAZAL TYPE 2, TANDEM DUPLICATE 1-RELATED OVOMUCOID-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010515.1|UniProtKB=W5MWY3 W5MWY3 PTHR23113:SF357 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS2 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000009682.1|UniProtKB=W5MTZ7 W5MTZ7 PTHR45628:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT R-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1E voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873 trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;calcium ion import#GO:0070509;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;calcium ion transmembrane transport#GO:0070588;inorganic ion import across plasma membrane#GO:0099587;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;import across plasma membrane#GO:0098739;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 transmembrane transporter complex#GO:1902495;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell body#GO:0044297;calcium channel complex#GO:0034704;transporter complex#GO:1990351;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 LEPOC|Ensembl=ENSLOCG00000007554.1|UniProtKB=W5MLA5 W5MLA5 PTHR21304:SF0 MICOS COMPLEX SUBUNIT MIC10 MICOS COMPLEX SUBUNIT MIC10 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000017832.1|UniProtKB=W5NMS6 W5NMS6 PTHR23074:SF14 AAA DOMAIN-CONTAINING FIDGETIN ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000005116.1|UniProtKB=W5MCQ9 W5MCQ9 PTHR24271:SF54 KALLIKREIN-RELATED COMPLEMENT FACTOR D serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000002273.1|UniProtKB=W5M2Q5 W5M2Q5 PTHR11208:SF30 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 1 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;poly(A) binding#GO:0008143;mRNA binding#GO:0003729 regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000016304.1|UniProtKB=W5NHL5 W5NHL5 PTHR19957:SF136 SYNTAXIN SYNTAXIN 11B, TANDEM DUPLICATE 1-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;exocytosis#GO:0006887;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;export from cell#GO:0140352;vesicle fusion#GO:0006906;protein transport#GO:0015031;secretion by cell#GO:0032940;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179 intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;SNARE complex#GO:0031201;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000003926.1|UniProtKB=W5M8I5 W5M8I5 PTHR24396:SF21 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 236 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012875.1|UniProtKB=W5N5E0 W5N5E0 PTHR31278:SF2 CHCHD1 SMALL RIBOSOMAL SUBUNIT PROTEIN MS37 LEPOC|Ensembl=ENSLOCG00000005515.1|UniProtKB=W5ME70 W5ME70 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072 metabolic process#GO:0008152;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 LEPOC|Ensembl=ENSLOCG00000017753.1|UniProtKB=W5NMJ8 W5NMJ8 PTHR10494:SF5 BONE MORPHOGENETIC PROTEIN INHIBITOR, NOGGIN NOGGIN molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;regionalization#GO:0003002;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of BMP signaling pathway#GO:0030510;multicellular organism development#GO:0007275;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;dorsal/ventral pattern formation#GO:0009953;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;system development#GO:0048731;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;pattern specification process#GO:0007389;regulation of signaling#GO:0023051 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012922.1|UniProtKB=W5N5K7 W5N5K7 PTHR15551:SF3 LIM DOMAIN ONLY 7 LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092 regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of actin filament bundle assembly#GO:0032231;regulation of cell-matrix adhesion#GO:0001952;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of cell junction assembly#GO:1901888;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229;stress fiber#GO:0001725;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actomyosin#GO:0042641;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000000460.1|UniProtKB=W5LWJ5 W5LWJ5 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000008006.1|UniProtKB=W5MMW2 W5MMW2 PTHR11132:SF293 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E4 active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000010923.1|UniProtKB=W5MYH1 W5MYH1 PTHR22625:SF37 PLEXIN PLEXIN-A2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system development#GO:0048731;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell differentiation#GO:0045595;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;synapse assembly#GO:0007416;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell differentiation#GO:0045597;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;cellular component biogenesis#GO:0044085 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002936.1|UniProtKB=W5M4Z8 W5M4Z8 PTHR11848:SF315 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 6-A cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000018010.1|UniProtKB=W5NNA2 W5NNA2 PTHR24247:SF16 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1B transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186 dendritic tree#GO:0097447;dendrite#GO:0030425;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000007204.1|UniProtKB=W5MK12 W5MK12 PTHR23067:SF13 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385A intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000002345.1|UniProtKB=W5M2Z0 W5M2Z0 PTHR24248:SF143 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE RECEPTOR D4A postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;negative regulation of cellular process#GO:0048523;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;adrenergic receptor signaling pathway#GO:0071875;negative regulation of cell communication#GO:0010648;response to nitrogen compound#GO:1901698;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000005646.1|UniProtKB=W5MEL1 W5MEL1 PTHR10270:SF216 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-17 sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;formation of primary germ layer#GO:0001704;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;negative regulation of cell communication#GO:0010648;positive regulation of macromolecule biosynthetic process#GO:0010557;angiogenesis#GO:0001525;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of transcription by RNA polymerase II#GO:0006357;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;endoderm formation#GO:0001706;embryo development#GO:0009790;negative regulation of signal transduction#GO:0009968;vasculogenesis#GO:0001570;positive regulation of macromolecule metabolic process#GO:0010604;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of macromolecule biosynthetic process#GO:0010556;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;tube development#GO:0035295;tissue development#GO:0009888;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;positive regulation of metabolic process#GO:0009893;gastrulation#GO:0007369;blood vessel morphogenesis#GO:0048514;cell differentiation#GO:0030154;circulatory system development#GO:0072359;positive regulation of transcription by RNA polymerase II#GO:0045944;endoderm development#GO:0007492;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;heart development#GO:0007507 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012606.1|UniProtKB=W5N4F6 W5N4F6 PTHR13680:SF34 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 ZGC:110843 iron-sulfur cluster binding#GO:0051536;catalytic activity#GO:0003824;small molecule binding#GO:0036094;transferase activity#GO:0016740;binding#GO:0005488;transaminase activity#GO:0008483 intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000011298.1|UniProtKB=W5MZS5 W5MZS5 PTHR46759:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72 LEPOC|Ensembl=ENSLOCG00000003261.1|UniProtKB=W5M643 W5M643 PTHR24107:SF2 YNEIN REGULATORY COMPLEX SUBUNIT 5 NLR FAMILY CARD DOMAIN CONTAINING 3 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002580.1|UniProtKB=W5M3S6 W5M3S6 PTHR20990:SF1 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11C organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;peroxisome organization#GO:0007031 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000002536.1|UniProtKB=W5M3M5 W5M3M5 PTHR16083:SF39 LEUCINE RICH REPEAT CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE LRSAM1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008048.1|UniProtKB=W5MN15 W5MN15 PTHR23311:SF5 HEAT SHOCK REGULATED 2 CENTROSOMAL PROTEIN OF 72 KDA LEPOC|Ensembl=ENSLOCG00000011731.1|UniProtKB=W5N1A9 W5N1A9 PTHR45882:SF4 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>PITX#P06722 LEPOC|Ensembl=ENSLOCG00000002322.1|UniProtKB=W5M2Y6 W5M2Y6 PTHR11963:SF4 LEUCINE AMINOPEPTIDASE-RELATED AMINOPEPTIDASE NPEPL1-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015710.1|UniProtKB=W5NFD0 W5NFD0 PTHR46186:SF12 CYSTATIN CYSTATIN C (AMYLOID ANGIOPATHY AND CEREBRAL HEMORRHAGE)-RELATED endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 vesicle#GO:0031982;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000014306.1|UniProtKB=W5NAF8 W5NAF8 PTHR11850:SF190 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS3 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;positive regulation of biological process#GO:0048518;sensory system development#GO:0048880;embryonic pattern specification#GO:0009880;nervous system development#GO:0007399;embryo development#GO:0009790;head development#GO:0060322;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;eye development#GO:0001654;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016552.1|UniProtKB=W5NII4 W5NII4 PTHR18914:SF30 ALPHA CATENIN VINCULIN_ALPHA-CATENIN FAMILY MEMBER 1 cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell migration#GO:0016477;cell motility#GO:0048870;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;anchoring junction#GO:0070161;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000005512.1|UniProtKB=W5ME46 W5ME46 PTHR22367:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 14 COILED-COIL DOMAIN-CONTAINING PROTEIN 14 protein localization to centrosome#GO:0071539;protein localization to cytoskeleton#GO:0044380;macromolecule localization#GO:0033036;protein localization to organelle#GO:0033365;protein localization to microtubule cytoskeleton#GO:0072698;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to microtubule organizing center#GO:1905508 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriolar satellite#GO:0034451;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000004403.1|UniProtKB=W5MA53 W5MA53 PTHR13071:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S22 SMALL RIBOSOMAL SUBUNIT PROTEIN MS22 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000003211.1|UniProtKB=W5M5Y7 W5M5Y7 PTHR11414:SF21 CYSTATIN FAMILY MEMBER CYSTATIN 14B, TANDEM DUPLICATE 2-RELATED enzyme regulator activity#GO:0030234;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000017375.1|UniProtKB=W5NLH1 W5NLH1 PTHR24233:SF10 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 13 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014893.1|UniProtKB=W5NCI1 W5NCI1 PTHR46005:SF1 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 35 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of developmental process#GO:0050793;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;regulation of cell size#GO:0008361;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;regulation of axonogenesis#GO:0050770;regulation of anatomical structure size#GO:0090066;regulation of cell projection organization#GO:0031344 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 GTPase-activating protein#PC00257;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000016683.1|UniProtKB=W5NJ05 W5NJ05 PTHR15288:SF3 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2A guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000011566.1|UniProtKB=W5N0Q4 W5N0Q4 PTHR46753:SF3 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 PDZ DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010834.1|UniProtKB=W5MY33 W5MY33 PTHR11615:SF377 NITRATE, FORMATE, IRON DEHYDROGENASE NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;electron transfer activity#GO:0009055;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775 membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015667.1|UniProtKB=W5NF75 W5NF75 PTHR24241:SF143 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PYROGLUTAMYLATED RF-AMIDE PEPTIDE RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015665.1|UniProtKB=W5NF74 W5NF74 PTHR10740:SF1 TRANSFORMING GROWTH FACTOR ALPHA PROTRANSFORMING GROWTH FACTOR ALPHA molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cellular component organization#GO:0051130;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic cell cycle#GO:0007346;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of cell cycle#GO:0045787;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 LEPOC|Ensembl=ENSLOCG00000002759.1|UniProtKB=W5M4D9 W5M4D9 PTHR31584:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11 LEPOC|Ensembl=ENSLOCG00000009931.1|UniProtKB=W5MUT6 W5MUT6 PTHR10880:SF55 MORTALITY FACTOR 4-LIKE PROTEIN MSL COMPLEX SUBUNIT 3 binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;chromatin binding#GO:0003682;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;chromatin#GO:0000785;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001687.1|UniProtKB=W5M0N1 W5M0N1 PTHR14789:SF4 CHONDROLECTIN VARIANT CHODLFDELTAE. ENDOSIALIN binding#GO:0005488;protein binding#GO:0005515;extracellular matrix binding#GO:0050840 cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 LEPOC|Ensembl=ENSLOCG00000002511.1|UniProtKB=W5M3L7 W5M3L7 PTHR23505:SF4 SPINSTER SPHINGOSINE-1-PHOSPHATE TRANSPORTER SPNS2 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 establishment of localization#GO:0051234;transport#GO:0006810;lipid transport#GO:0006869;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;localization#GO:0051179;lipid localization#GO:0010876;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009493.1|UniProtKB=W5MTA0 W5MTA0 PTHR24023:SF1128 COLLAGEN ALPHA COLLAGEN ALPHA-6(IV) CHAIN ISOFORM X1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000013967.1|UniProtKB=W5N9B0 W5N9B0 PTHR10856:SF17 CORONIN CORONIN-2B protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cell-substrate junction organization#GO:0150115;focal adhesion assembly#GO:0048041;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cell-substrate junction assembly#GO:0007044;cellular component organization#GO:0016043 actin filament#GO:0005884;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000004925.1|UniProtKB=W5MC17 W5MC17 PTHR43313:SF12 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 5 catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 retinoid metabolic process#GO:0001523;isoprenoid metabolic process#GO:0006720;diterpenoid metabolic process#GO:0016101;metabolic process#GO:0008152;terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;cellular process#GO:0009987 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006821.1|UniProtKB=W5MIN7 W5MIN7 PTHR21538:SF21 ANILLIN/RHOTEKIN RTKN RHOTEKIN-2 mitotic cell cycle#GO:0000278;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;cell division#GO:0051301;cell cycle#GO:0007049;cortical actin cytoskeleton organization#GO:0030866;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;hemopoiesis#GO:0030097;positive regulation of cellular process#GO:0048522;mitotic cell cycle process#GO:1903047;cellular developmental process#GO:0048869;developmental process#GO:0032502;septin cytoskeleton organization#GO:0032185;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;positive regulation of cell population proliferation#GO:0008284;cellular component organization#GO:0016043;cytoskeleton-dependent cytokinesis#GO:0061640;septin ring organization#GO:0031106;cytokinetic process#GO:0032506;cytokinesis#GO:0000910;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actomyosin contractile ring assembly#GO:0000915;cellular component organization or biogenesis#GO:0071840 actomyosin contractile ring#GO:0005826;contractile ring#GO:0070938;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000007024.1|UniProtKB=W5MJG7 W5MJG7 PTHR43674:SF17 NITRILASE C965.09-RELATED BETA-UREIDOPROPIONASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Pyrimidine Metabolism#P02771>Beta-Ureidopropionase#P03127 LEPOC|Ensembl=ENSLOCG00000010568.1|UniProtKB=W5MX44 W5MX44 PTHR11006:SF92 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 2 transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;histone modifying activity#GO:0140993 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007343.1|UniProtKB=W5MKJ1 W5MKJ1 PTHR11034:SF18 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG1 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000008478.1|UniProtKB=W5MPK7 W5MPK7 PTHR13703:SF41 SMAD SMAD FAMILY MEMBER 9 cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to growth factor stimulus#GO:0071363;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to transforming growth factor beta#GO:0071559;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 TGF-beta signaling pathway#P00052>RSmads#P01292;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819 LEPOC|Ensembl=ENSLOCG00000001472.1|UniProtKB=W5LZY4 W5LZY4 PTHR23343:SF117 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 1-LIKE protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899 biological regulation#GO:0065007;fertilization#GO:0009566;reproductive process#GO:0022414;regulation of reproductive process#GO:2000241;multicellular organismal process#GO:0032501;regulation of biological process#GO:0050789;cellular process#GO:0009987;negative regulation of biological process#GO:0048519;single fertilization#GO:0007338;cell-cell recognition#GO:0009988;binding of sperm to zona pellucida#GO:0007339;sexual reproduction#GO:0019953;cell activation#GO:0001775;cell recognition#GO:0008037;sperm-egg recognition#GO:0035036 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 LEPOC|Ensembl=ENSLOCG00000008742.1|UniProtKB=W5MQI2 W5MQI2 PTHR13555:SF67 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER PROTEIN 474 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008624.1|UniProtKB=W5MQ28 W5MQ28 PTHR11375:SF5 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER E phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;histone binding#GO:0042393;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;binding#GO:0005488 regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006315.1|UniProtKB=W5MGW7 W5MGW7 PTHR23037:SF34 CYTOKINE RECEPTOR THROMBOPOIETIN RECEPTOR ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014266.1|UniProtKB=W5NAA7 W5NAA7 PTHR11787:SF4 RAB GDP-DISSOCIATION INHIBITOR CHM, RAB ESCORT PROTEIN 1 vesicle-mediated transport#GO:0016192;protein targeting#GO:0006605;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein targeting to membrane#GO:0006612;transport#GO:0006810;localization within membrane#GO:0051668 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000016641.1|UniProtKB=W5NIU8 W5NIU8 PTHR24366:SF190 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000004153.1|UniProtKB=W5M9B1 W5M9B1 PTHR11588:SF298 TUBULIN TUBULIN ALPHA-1C CHAIN guanyl nucleotide binding#GO:0019001;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;microtubule-based process#GO:0007017;neurogenesis#GO:0022008;cell cycle#GO:0007049;cellular component organization#GO:0016043;mitotic cell cycle#GO:0000278;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 tubulin#PC00228;cytoskeletal protein#PC00085 Gonadotropin-releasing hormone receptor pathway#P06664>Tubulin#P06772 LEPOC|Ensembl=ENSLOCG00000004944.1|UniProtKB=W5MC98 W5MC98 PTHR45623:SF6 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD5 ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393;catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;DNA binding#GO:0003677;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008885.1|UniProtKB=W5MR06 W5MR06 PTHR14543:SF1 PROTRUDIN PROTRUDIN positive regulation of cell growth#GO:0030307;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of cell differentiation#GO:0045597;neuron differentiation#GO:0030182;protein localization to cell periphery#GO:1990778;regulation of anatomical structure size#GO:0090066;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;neuron development#GO:0048666;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of multicellular organismal process#GO:0051240;endoplasmic reticulum organization#GO:0007029;regulation of biological process#GO:0050789;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;transport#GO:0006810;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;positive regulation of cell projection organization#GO:0031346;localization within membrane#GO:0051668;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;endoplasmic reticulum tubular network organization#GO:0071786;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;protein localization to plasma membrane#GO:0072659;regulation of axonogenesis#GO:0050770;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;regulation of cell growth#GO:0001558;cellular component assembly#GO:0022607;regulation of cell size#GO:0008361;cellular response to growth factor stimulus#GO:0071363;positive regulation of axonogenesis#GO:0050772;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;positive regulation of growth#GO:0045927;signaling#GO:0023052;cell projection organization#GO:0030030;cell differentiation#GO:0030154;positive regulation of nervous system development#GO:0051962;cellular response to endogenous stimulus#GO:0071495;regulation of multicellular organismal development#GO:2000026;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;intracellular protein localization#GO:0008104;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;macromolecule localization#GO:0033036;system development#GO:0048731;regulation of nervous system development#GO:0051960;enzyme-linked receptor protein signaling pathway#GO:0007167;localization#GO:0051179;cell communication#GO:0007154;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of growth#GO:0040008 endoplasmic reticulum#GO:0005783;membrane#GO:0016020;endoplasmic reticulum tubular network#GO:0071782;neuron projection#GO:0043005;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;axon#GO:0030424;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;growth cone#GO:0030426;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;distal axon#GO:0150034;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008794.1|UniProtKB=W5MQP6 W5MQP6 PTHR12665:SF12 ORMDL PROTEINS ORM1-LIKE PROTEIN 1 intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;ceramide metabolic process#GO:0006672;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;homeostatic process#GO:0042592;cellular process#GO:0009987;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088 protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000017448.1|UniProtKB=W5NLP4 W5NLP4 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN LOW QUALITY PROTEIN: ODORANT RECEPTOR 125-6-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006222.1|UniProtKB=W5MGK6 W5MGK6 PTHR14309:SF7 EXPRESSED PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY B MEMBER 1 regulation of biological process#GO:0050789;regulation of cell differentiation#GO:0045595;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004316.1|UniProtKB=W5M9V6 W5M9V6 PTHR23030:SF45 PCD6 INTERACTING PROTEIN-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23 cellular localization#GO:0051641;protein transport#GO:0015031;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;establishment of protein localization to vacuole#GO:0072666;endocytic recycling#GO:0032456;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;endosomal transport#GO:0016197;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein metabolic process#GO:0019538;localization#GO:0051179;protein localization to vacuole#GO:0072665;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;early endosome to late endosome transport#GO:0045022;multivesicular body sorting pathway#GO:0071985 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006213.1|UniProtKB=W5MGJ6 W5MGJ6 PTHR12749:SF0 EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1 DNA EXCISION REPAIR PROTEIN ERCC-1 nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;DNA binding#GO:0003677 primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular response to environmental stimulus#GO:0104004;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to radiation#GO:0071478;mitotic recombination#GO:0006312;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;response to UV#GO:0009411;cellular response to abiotic stimulus#GO:0071214;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleotide-excision repair complex#GO:0000109;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000009211.1|UniProtKB=W5MS84 W5MS84 PTHR24278:SF0 COAGULATION FACTOR VITAMIN K-DEPENDENT PROTEIN C endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>PC#P00426;Blood coagulation#P00011>APC#P00423 LEPOC|Ensembl=ENSLOCG00000018143.1|UniProtKB=W5NNN5 W5NNN5 PTHR12002:SF84 CLAUDIN CLAUDIN-24 cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000014497.1|UniProtKB=W5NB36 W5NB36 PTHR46624:SF2 AGAP002036-PA SI:CH211-11N16.2 phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;lipid storage#GO:0019915;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;lipid droplet organization#GO:0034389 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811 LEPOC|Ensembl=ENSLOCG00000008169.1|UniProtKB=W5MNH0 W5MNH0 PTHR14224:SF27 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14B LEPOC|Ensembl=ENSLOCG00000007545.1|UniProtKB=W5ML93 W5ML93 PTHR23292:SF35 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LITAF DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;zinc ion binding#GO:0008270;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 membrane#GO:0016020;vesicle membrane#GO:0012506;lysosomal membrane#GO:0005765;nucleus#GO:0005634;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;late endosome membrane#GO:0031902;cytoplasmic side of membrane#GO:0098562;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;side of membrane#GO:0098552;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016393.1|UniProtKB=W5NHY5 W5NHY5 PTHR45712:SF18 AGAP008170-PA WU:FC23C09 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000014377.1|UniProtKB=W5NAP1 W5NAP1 PTHR14344:SF3 WD REPEAT PROTEIN TRNA (34-2'-O)-METHYLTRANSFERASE REGULATOR WDR6 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006541.1|UniProtKB=W5MHP5 W5MHP5 PTHR24078:SF586 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 5 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007920.1|UniProtKB=W5MML9 W5MML9 PTHR19876:SF20 COATOMER SI:CH211-154O6.3 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;COPI-coated vesicle#GO:0030137;cytoplasm#GO:0005737;vesicle coat#GO:0030120;intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000015938.1|UniProtKB=W5NG65 W5NG65 PTHR19305:SF5 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 25 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905 cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;exocytic process#GO:0140029;vesicle fusion to plasma membrane#GO:0099500;regulated exocytosis#GO:0045055;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;export from cell#GO:0140352;secretion by cell#GO:0032940;cellular localization#GO:0051641;synaptic vesicle membrane organization#GO:0048499;membrane fusion#GO:0061025;neurotransmitter secretion#GO:0007269;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;vesicle fusion#GO:0006906;anterograde trans-synaptic signaling#GO:0098916;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150;SNARE protein#PC00034 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Synaptic vesicle trafficking#P05734>SNAP-25#P05778;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996 LEPOC|Ensembl=ENSLOCG00000010392.1|UniProtKB=W5MWI4 W5MWI4 PTHR18867:SF12 RAD50 DNA REPAIR PROTEIN RAD50 DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;telomeric repeat DNA binding#GO:0042162;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697 nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;response to stimulus#GO:0050896;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;organelle organization#GO:0006996;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;telomere maintenance via telomerase#GO:0007004;telomere maintenance via telomere lengthening#GO:0010833;mitotic recombination#GO:0006312;sexual reproduction#GO:0019953;telomere organization#GO:0032200;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;reproductive process#GO:0022414;RNA-templated DNA biosynthetic process#GO:0006278;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 organelle lumen#GO:0043233;chromosome#GO:0005694;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;condensed chromosome#GO:0000793;nuclear protein-containing complex#GO:0140513;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000007639.1|UniProtKB=W5MLK7 W5MLK7 PTHR47980:SF15 LD44762P RAS-RELATED PROTEIN RAB-3C myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810 cell junction#GO:0030054;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endosome#GO:0005768;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 Synaptic vesicle trafficking#P05734>Rab3A#P05780 LEPOC|Ensembl=ENSLOCG00000013170.1|UniProtKB=W5N6G7 W5N6G7 PTHR32022:SF10 D-GLUTAMATE CYCLASE, MITOCHONDRIAL D-GLUTAMATE CYCLASE, MITOCHONDRIAL cyclase activity#GO:0009975;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 lyase#PC00144;cyclase#PC00079 LEPOC|Ensembl=ENSLOCG00000011886.1|UniProtKB=W5N1V5 W5N1V5 PTHR33802:SF3 SI:CH211-161H7.5-RELATED SUBFAMILY NOT NAMED LEPOC|Ensembl=ENSLOCG00000009079.1|UniProtKB=W5MRQ6 W5MRQ6 PTHR23097:SF90 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11B transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003282.1|UniProtKB=W5M671 W5M671 PTHR12015:SF204 SMALL INDUCIBLE CYTOKINE A C-X-C MOTIF CHEMOKINE 13 cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000015170.1|UniProtKB=W5NDF9 W5NDF9 PTHR45740:SF14 POLY [ADP-RIBOSE] POLYMERASE SI:CH211-244B2.4 pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000001971.1|UniProtKB=W5M1M8 W5M1M8 PTHR11644:SF24 CYTIDINE DEAMINASE CYTIDINE DEAMINASE catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;nucleoside catabolic process#GO:0009164 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 deaminase#PC00088 LEPOC|Ensembl=ENSLOCG00000017051.1|UniProtKB=W5NKB3 W5NKB3 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004166.1|UniProtKB=W5M9C3 W5M9C3 PTHR10153:SF41 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL INTERMEDIATE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 4 channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;calcium-activated potassium channel activity#GO:0015269;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion-gated channel activity#GO:0022839;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;gated channel activity#GO:0022836;binding#GO:0005488;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;calmodulin binding#GO:0005516 transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell body#GO:0044297;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000016018.1|UniProtKB=W5NGH2 W5NGH2 PTHR11848:SF226 TGF-BETA FAMILY LEFT-RIGHT DETERMINATION FACTOR signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;pattern specification process#GO:0007389;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;regionalization#GO:0003002;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;anterior/posterior axis specification#GO:0009948;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000004121.1|UniProtKB=W5M990 W5M990 PTHR28630:SF28 FAMILY NOT NAMED PROSTAMIDE_PROSTAGLANDIN F SYNTHASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxoacid metabolic process#GO:0043436;prostaglandin metabolic process#GO:0006693;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;unsaturated fatty acid biosynthetic process#GO:0006636 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000011462.1|UniProtKB=W5N0C3 W5N0C3 PTHR15090:SF0 SEQUESTOSOME 1-RELATED SEQUESTOSOME-1 protein binding#GO:0005515;modification-dependent protein binding#GO:0140030;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;polyubiquitin modification-dependent protein binding#GO:0031593 process utilizing autophagic mechanism#GO:0061919;vesicle organization#GO:0016050;endosome organization#GO:0007032;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;macroautophagy#GO:0016236;endomembrane system organization#GO:0010256;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization#GO:0016043;organelle organization#GO:0006996 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;autophagosome#GO:0005776 LEPOC|Ensembl=ENSLOCG00000006379.1|UniProtKB=W5MH41 W5MH41 PTHR45771:SF9 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-C4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;skeletal system morphogenesis#GO:0048705;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regionalization#GO:0003002;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of biological process#GO:0048518;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;anterior/posterior pattern specification#GO:0009952;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;skeletal system development#GO:0001501;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008277.1|UniProtKB=W5MNU4 W5MNU4 PTHR23089:SF55 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787 purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000006550.1|UniProtKB=W5MHQ7 W5MHQ7 PTHR11267:SF213 T-BOX PROTEIN-RELATED SPADETAIL DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell fate specification#GO:0001708;heart development#GO:0007507;cellular process#GO:0009987;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;heart morphogenesis#GO:0003007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000010154.1|UniProtKB=W5MVM4 W5MVM4 PTHR31770:SF2 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-1 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000000472.1|UniProtKB=W5LWL1 W5LWL1 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED SI:DKEYP-69E1.8 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000004984.1|UniProtKB=W5MC97 W5MC97 PTHR12002:SF13 CLAUDIN CLAUDIN-10 transporter activity#GO:0005215;paracellular tight junction channel activity#GO:0160187 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184;establishment of localization#GO:0051234;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;transport#GO:0006810;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cellular process#GO:0009987;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000005845.1|UniProtKB=W5MF98 W5MF98 PTHR19969:SF18 SH2-SH3 ADAPTOR PROTEIN-RELATED GRB2 RELATED ADAPTOR PROTEIN B signaling adaptor activity#GO:0035591;protein binding#GO:0005515;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971 regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell migration#GO:0016477;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012248.1|UniProtKB=W5N360 W5N360 PTHR21437:SF3 WIDE AWAKE ANKYRIN REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 1 microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of establishment or maintenance of cell polarity#GO:0032878;organelle localization#GO:0051640;establishment or maintenance of cell polarity#GO:0007163;microtubule cytoskeleton organization#GO:0000226;spindle localization#GO:0051653;cellular localization#GO:0051641;localization#GO:0051179;cell cycle process#GO:0022402;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;establishment of organelle localization#GO:0051656;mitotic cell cycle#GO:0000278 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000001992.1|UniProtKB=W5M1P3 W5M1P3 PTHR23055:SF57 CALCIUM BINDING PROTEINS NEURON-SPECIFIC CALCIUM-BINDING PROTEIN HIPPOCALCIN small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000002383.1|UniProtKB=W5M346 W5M346 PTHR24416:SF297 TYROSINE-PROTEIN KINASE RECEPTOR DISCOIDIN DOMAIN-CONTAINING RECEPTOR 2 signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;collagen binding#GO:0005518;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714 regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014861.1|UniProtKB=W5NCE8 W5NCE8 PTHR16092:SF14 SEC3/SYNTAXIN-RELATED EXOCYST COMPLEX COMPONENT 1 phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546 cellular process#GO:0009987;Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;localization within membrane#GO:0051668;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport to the plasma membrane#GO:0098876;secretion by cell#GO:0032940;exocytosis#GO:0006887 cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;exocyst#GO:0000145;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150;SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000006794.1|UniProtKB=W5MIJ7 W5MIJ7 PTHR43818:SF14 BCDNA.GH03377 GLUCOSE-FRUCTOSE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000003307.1|UniProtKB=W5M691 W5M691 PTHR34251:SF1 LEUCINE-, GLUTAMATE- AND LYSINE-RICH PROTEIN 1 LEUCINE, GLUTAMATE AND LYSINE RICH 1 LEPOC|Ensembl=ENSLOCG00000006508.1|UniProtKB=W5MHK7 W5MHK7 PTHR48015:SF31 SERINE/THREONINE-PROTEIN KINASE TAO NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000001321.1|UniProtKB=W5LZG4 W5LZG4 PTHR24006:SF682 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012780.1|UniProtKB=W5N521 W5N521 PTHR14890:SF1 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 100 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 100 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009007.1|UniProtKB=W5MRG3 W5MRG3 PTHR22763:SF163 RING ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF139 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000000796.1|UniProtKB=W5LXQ4 W5LXQ4 PTHR23236:SF16 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H POLYADENYLATE-BINDING PROTEIN 2 binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000003201.1|UniProtKB=W5M5X6 W5M5X6 PTHR25465:SF32 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003086.1|UniProtKB=W5M5I2 W5M5I2 PTHR45721:SF2 LAMIN DM0-RELATED LAMIN-B2 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 localization#GO:0051179;localization within membrane#GO:0051668;organelle localization#GO:0051640;regulation of macromolecule metabolic process#GO:0060255;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;nuclear migration#GO:0007097;heterochromatin formation#GO:0031507;intracellular protein localization#GO:0008104;regulation of gene expression#GO:0010468;nuclear envelope organization#GO:0006998;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;establishment of localization#GO:0051234;transport#GO:0006810;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;membrane organization#GO:0061024;chromatin organization#GO:0006325;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule localization#GO:0033036;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;protein localization to nucleus#GO:0034504;regulation of metabolic process#GO:0019222;cellular localization#GO:0051641;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;endomembrane system organization#GO:0010256;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 FAS signaling pathway#P00020>Nuclear Lamin#P00616 LEPOC|Ensembl=ENSLOCG00000009741.1|UniProtKB=W5MU44 W5MU44 PTHR12393:SF8 SPHINGOMYELIN PHOSPHODIESTERASE RELATED SPHINGOMYELIN PHOSPHODIESTERASE 2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298 organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;phosphorus metabolic process#GO:0006793;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;ceramide metabolic process#GO:0006672 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;plasma membrane raft#GO:0044853;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane raft#GO:0045121;membrane microdomain#GO:0098857;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;caveola#GO:0005901 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000017665.1|UniProtKB=W5NMB1 W5NMB1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004935.1|UniProtKB=W5MC34 W5MC34 PTHR11390:SF21 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-ALPHA macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097 cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 chromosome#GO:0005694;DNA helicase complex#GO:0033202;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006815.1|UniProtKB=W5MIM9 W5MIM9 PTHR23295:SF3 NUCLEAR RECEPTOR COACTIVATOR 5-RELATED NUCLEAR RECEPTOR COACTIVATOR 5 regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000002269.1|UniProtKB=W5M2Q2 W5M2Q2 PTHR48177:SF1 TRANSMEMBRANE PROTEIN 189 TRANSMEMBRANE PROTEIN 189 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000017114.1|UniProtKB=W5NKJ3 W5NKJ3 PTHR12292:SF9 RWD DOMAIN-CONTAINING PROTEIN RWD DOMAIN-CONTAINING PROTEIN 1 cellular response to steroid hormone stimulus#GO:0071383;nuclear receptor-mediated signaling pathway#GO:0141193;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;cellular process#GO:0009987;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;intracellular signal transduction#GO:0035556;cellular response to chemical stimulus#GO:0070887;response to steroid hormone#GO:0048545;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;intracellular receptor signaling pathway#GO:0030522;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;steroid hormone receptor signaling pathway#GO:0043401;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011372.1|UniProtKB=W5N022 W5N022 PTHR24174:SF18 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 CASKIN-2 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001565.1|UniProtKB=W5M077 W5M077 PTHR15665:SF1 ASTEROID PROTEIN SINGLE-STRAND DNA ENDONUCLEASE ASTE1 LEPOC|Ensembl=ENSLOCG00000004048.1|UniProtKB=W5M8X4 W5M8X4 PTHR23115:SF228 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 2 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000013178.1|UniProtKB=W5N6I2 W5N6I2 PTHR31061:SF37 LD22376P HEPARAN-ALPHA-GLUCOSAMINIDE N-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080 catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;glycoprotein metabolic process#GO:0009100 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323 LEPOC|Ensembl=ENSLOCG00000011148.1|UniProtKB=W5MZ85 W5MZ85 PTHR17103:SF13 NEUREXOPHILIN NEUREXOPHILIN-1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646 GABA-ergic synapse#GO:0098982;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004716.1|UniProtKB=W5MBC0 W5MBC0 PTHR10194:SF142 RAS GTPASE-ACTIVATING PROTEINS NEUROFIBROMIN GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 LEPOC|Ensembl=ENSLOCG00000004930.1|UniProtKB=W5MC22 W5MC22 PTHR31705:SF6 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000007940.1|UniProtKB=W5MMN1 W5MMN1 PTHR46907:SF2 HEAT SHOCK PROTEIN BETA-7-RELATED HEAT SHOCK PROTEIN BETA-7 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000015292.1|UniProtKB=W5NDW0 W5NDW0 PTHR23152:SF7 2-OXOGLUTARATE DEHYDROGENASE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX COMPONENT E1 catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;cellular process#GO:0009987;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099 mitochondrion#GO:0005739;cytosol#GO:0005829;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 TCA cycle#P00051>alphaketoglutarate Dehydrogenase#P01269 LEPOC|Ensembl=ENSLOCG00000008045.1|UniProtKB=W5MN08 W5MN08 PTHR22779:SF2 SD17342P TRANSMEMBRANE PROTEIN 170A organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;endoplasmic reticulum tubular network organization#GO:0071786;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000001269.1|UniProtKB=W5LZ84 W5LZ84 PTHR47027:SF26 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005485.1|UniProtKB=W5ME21 W5ME21 PTHR23159:SF63 CENTROSOMAL PROTEIN 2 CILIARY ROOTLET COILED-COIL, ROOTLETIN FAMILY MEMBER 2 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014269.1|UniProtKB=W5NAB4 W5NAB4 PTHR23429:SF23 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;glucose-6-phosphate dehydrogenase activity#GO:0004345 glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;pentose-phosphate shunt, oxidative branch#GO:0009051;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000012465.1|UniProtKB=W5N3Y7 W5N3Y7 PTHR45823:SF1 T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN SAP DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007586.1|UniProtKB=W5MLE6 W5MLE6 PTHR12247:SF84 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 2 histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;protein binding#GO:0005515 negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003220.1|UniProtKB=W5M5Z3 W5M5Z3 PTHR24070:SF396 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN R-RAS2 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;TGF-beta signaling pathway#P00052>Ras-GTP#P01280 LEPOC|Ensembl=ENSLOCG00000009913.1|UniProtKB=W5MUQ5 W5MUQ5 PTHR12011:SF469 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E1 ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006061.1|UniProtKB=W5MG09 W5MG09 PTHR12822:SF3 PROTEIN YIPF PROTEIN YIPF2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000010289.1|UniProtKB=W5MW42 W5MW42 PTHR28582:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15 LEPOC|Ensembl=ENSLOCG00000020984.1|UniProtKB=W5NPB5 W5NPB5 PTHR22888:SF9 CYTOCHROME C OXIDASE, SUBUNIT II CYTOCHROME C OXIDASE SUBUNIT 2 monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;oxidoreductase complex#GO:1990204;organelle membrane#GO:0031090;transporter complex#GO:1990351 oxidoreductase#PC00176 Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06899;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06686;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#P06734 LEPOC|Ensembl=ENSLOCG00000004699.1|UniProtKB=W5MB70 W5MB70 PTHR11337:SF11 MUCIN/PORIMIN CD164 SIALOMUCIN-LIKE 2 PROTEIN vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000001816.1|UniProtKB=W5M155 W5M155 PTHR19423:SF1 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;kinase inhibitor activity#GO:0019210 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013597.1|UniProtKB=W5N808 W5N808 PTHR44229:SF2 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000014743.1|UniProtKB=W5NBZ6 W5NBZ6 PTHR11547:SF62 ARGININE OR CREATINE KINASE CREATINE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;modified amino acid metabolic process#GO:0006575;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;amino acid kinase#PC00045 LEPOC|Ensembl=ENSLOCG00000009234.1|UniProtKB=W5MSA3 W5MSA3 PTHR12707:SF0 PINN PININ nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000012935.1|UniProtKB=W5N5M0 W5N5M0 PTHR19290:SF9 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 6 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000010407.1|UniProtKB=W5MWJ9 W5MWJ9 PTHR12186:SF4 SIKE FAMILY MEMBER SUPPRESSOR OF IKBKE 1 LEPOC|Ensembl=ENSLOCG00000014507.1|UniProtKB=W5NB49 W5NB49 PTHR43851:SF4 FAMILY NOT NAMED ATYPICAL KINASE COQ8B, MITOCHONDRIAL small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ketone metabolic process#GO:0042180 LEPOC|Ensembl=ENSLOCG00000005649.1|UniProtKB=W5MEL5 W5MEL5 PTHR24345:SF93 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cellular process#GO:0009987;cell cycle process#GO:0022402;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850 membraneless organelle#GO:0043228;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000003333.1|UniProtKB=W5M6D1 W5M6D1 PTHR37397:SF1 SI:CH211-183D21.1 LTD DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008258.1|UniProtKB=W5MNT4 W5MNT4 PTHR24416:SF533 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007538.1|UniProtKB=W5ML86 W5ML86 PTHR19288:SF98 4-NITROPHENYLPHOSPHATASE-RELATED PYRIDOXAL (PYRIDOXINE, VITAMIN B6) PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015335.1|UniProtKB=W5NE09 W5NE09 PTHR45931:SF15 SI:CH211-59O9.10 SI:CH211-59O9.10 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005826.1|UniProtKB=W5MF75 W5MF75 PTHR11639:SF114 S100 CALCIUM-BINDING PROTEIN S100 CALCIUM BINDING PROTEIN V2 ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;perinuclear region of cytoplasm#GO:0048471;extracellular region#GO:0005576 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000003550.1|UniProtKB=W5M754 W5M754 PTHR43294:SF10 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;potassium ion homeostasis#GO:0055075;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;export from cell#GO:0140352;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000001606.1|UniProtKB=W5M0E5 W5M0E5 PTHR16216:SF11 DYNEIN ASSEMBLY FACTOR 5, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 5 protein binding#GO:0005515;binding#GO:0005488 cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;inner dynein arm assembly#GO:0036159;organelle assembly#GO:0070925;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017609.1|UniProtKB=W5NM55 W5NM55 PTHR24379:SF134 KRAB AND ZINC FINGER DOMAIN-CONTAINING RIKEN CDNA 2610008E11 GENE LIKE-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000014737.1|UniProtKB=W5NBY3 W5NBY3 PTHR45736:SF3 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 3 zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004200.1|UniProtKB=W5M9F5 W5M9F5 PTHR23150:SF33 SULFATASE MODIFYING FACTOR 1, 2 INACTIVE C-ALPHA-FORMYLGLYCINE-GENERATING ENZYME 2 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014439.1|UniProtKB=W5NAW3 W5NAW3 PTHR23039:SF2 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000011314.1|UniProtKB=W5MZU8 W5MZU8 PTHR22809:SF4 METHYLTRANSFERASE-RELATED TRNA N(3)-CYTIDINE METHYLTRANSFERASE METTL2A-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a tRNA#GO:0140101 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000001507.1|UniProtKB=W5M095 W5M095 PTHR13723:SF165 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 20 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000012340.1|UniProtKB=W5N3J0 W5N3J0 PTHR10159:SF40 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 5 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;gastrulation#GO:0007369;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;formation of primary germ layer#GO:0001704;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;embryo development#GO:0009790;endoderm formation#GO:0001706;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure formation involved in morphogenesis#GO:0048646;endoderm development#GO:0007492;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;tissue development#GO:0009888;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000007840.1|UniProtKB=W5MMB2 W5MMB2 PTHR45677:SF5 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 1 lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652 cell junction#GO:0030054;presynaptic active zone#GO:0048786;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;presynapse#GO:0098793 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 LEPOC|Ensembl=ENSLOCG00000006130.1|UniProtKB=W5MGA2 W5MGA2 PTHR47972:SF5 KINESIN-LIKE PROTEIN KLP-3 KINESIN-LIKE PROTEIN KIFC3 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000002013.1|UniProtKB=W5M1S3 W5M1S3 PTHR13848:SF1 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 1 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002577.1|UniProtKB=W5M3S1 W5M3S1 PTHR16019:SF5 SYNAPSE-ASSOCIATED PROTEIN BSD DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015552.1|UniProtKB=W5NET5 W5NET5 PTHR24240:SF16 OPSIN SHORT-WAVE-SENSITIVE OPSIN 1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;biological regulation#GO:0065007;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to radiation#GO:0071478;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628 cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002983.1|UniProtKB=W5M559 W5M559 PTHR42886:SF83 RE40534P-RELATED PROTEIN ABHD8 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity#GO:0016746;lipase activity#GO:0016298 primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;homeostatic process#GO:0042592;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000006776.1|UniProtKB=W5MIH5 W5MIH5 PTHR23424:SF35 SERUM AMYLOID A PROTEIN SAAL1 regulation of cell population proliferation#GO:0042127;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;positive regulation of epithelial cell proliferation#GO:0050679;biological regulation#GO:0065007 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219;apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000013233.1|UniProtKB=W5N6P2 W5N6P2 PTHR45672:SF3 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5 protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003373.1|UniProtKB=W5M6K6 W5M6K6 PTHR15622:SF1 WD40 REPEAT PROTEIN WD REPEAT AND SOCS BOX-CONTAINING PROTEIN 2 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 LEPOC|Ensembl=ENSLOCG00000014547.1|UniProtKB=W5NB94 W5NB94 PTHR47981:SF13 RAB FAMILY RAS-RELATED PROTEIN RAB-7A hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 vacuole organization#GO:0007033;localization#GO:0051179;cellular localization#GO:0051641;endosome to lysosome transport#GO:0008333;organelle assembly#GO:0070925;lysosomal transport#GO:0007041;vesicle fusion#GO:0006906;endocytosis#GO:0006897;cellular component organization#GO:0016043;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;vacuolar transport#GO:0007034;transport#GO:0006810;lytic vacuole organization#GO:0080171;phagolysosome assembly#GO:0001845;phagocytosis#GO:0006909;intracellular transport#GO:0046907;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;late endosome#GO:0005770;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000012016.1|UniProtKB=W5N2C1 W5N2C1 ASIC2 PTHR11690:SF128 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID SENSING ION CHANNEL SUBUNIT 2 gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000003951.1|UniProtKB=W5M8L3 W5M8L3 PTHR46453:SF5 PROTEIN KINASE C-BINDING PROTEIN 1 MYND-TYPE ZINC FINGER-CONTAINING CHROMATIN READER ZMYND8 ISOFORM X1-RELATED transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005237.1|UniProtKB=W5MD50 W5MD50 PTHR24028:SF41 CADHERIN-87A PROTOCADHERIN-17 synapse assembly#GO:0007416;cell junction organization#GO:0034330;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;cell adhesion#GO:0007155;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000018197.1|UniProtKB=W5NNT9 W5NNT9 PTHR33766:SF2 PROTEIN FAM181B PROTEIN FAM181B LEPOC|Ensembl=ENSLOCG00000013258.1|UniProtKB=W5N6S1 W5N6S1 PTHR15907:SF30 DUF614 FAMILY PROTEIN-RELATED PLAC8 ONZIN RELATED PROTEIN 5 ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000000582.1|UniProtKB=W5LWY7 W5LWY7 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012655.1|UniProtKB=W5N4L8 W5N4L8 PTHR46439:SF5 CYSTEINE-RICH MOTOR NEURON 1 PROTEIN CYSTEINE-RICH MOTOR NEURON 1 PROTEIN-LIKE ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000010287.1|UniProtKB=W5MW41 W5MW41 PTHR10913:SF9 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 4 cellular process#GO:0009987;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000007619.1|UniProtKB=W5MLI4 W5MLI4 PTHR47305:SF1 BEN DOMAIN-CONTAINING PROTEIN 2 BEN DOMAIN CONTAINING 2 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;response to stimulus#GO:0050896;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;sexual reproduction#GO:0019953 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001753.1|UniProtKB=W5M0W5 W5M0W5 PTHR10498:SF6 PARALEMMIN-RELATED PARALEMMIN-1 protein-membrane adaptor activity#GO:0043495;cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of cell projection assembly#GO:0060491;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of filopodium assembly#GO:0051489;regulation of plasma membrane bounded cell projection organization#GO:0120035;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental process#GO:0032502;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental maturation#GO:0021700;positive regulation of cellular process#GO:0048522;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;nervous system development#GO:0007399;positive regulation of cellular component biogenesis#GO:0044089;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 synaptic membrane#GO:0097060;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;plasma membrane region#GO:0098590;intracellular organelle#GO:0043229;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;actin-based cell projection#GO:0098858;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000003900.1|UniProtKB=W5M8E6 W5M8E6 PTHR11429:SF0 MYELIN BASIC PROTEIN MYELIN BASIC PROTEIN cellular process#GO:0009987;cellular component organization#GO:0016043;nervous system development#GO:0007399;membrane organization#GO:0061024;multicellular organismal process#GO:0032501;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;myelination#GO:0042552;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;myelin sheath#GO:0043209;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;main axon#GO:0044304;neuron projection#GO:0043005;cell body#GO:0044297;axon#GO:0030424 structural protein#PC00211;myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000000634.1|UniProtKB=W5LX43 W5LX43 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017489.1|UniProtKB=W5NLT5 W5NLT5 PTHR24232:SF86 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 174-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001120.1|UniProtKB=W5LYQ3 W5LYQ3 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010798.1|UniProtKB=W5MXX6 W5MXX6 PTHR10218:SF73 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-2 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;G protein-coupled adenosine receptor signaling pathway#GO:0001973;cell surface receptor signaling pathway#GO:0007166;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 G-protein#PC00020;heterotrimeric G-protein#PC00117 Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;PI3 kinase pathway#P00048>Galpha#P01199;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid proenkephalin pathway#P05915>G-protein#P05994 LEPOC|Ensembl=ENSLOCG00000017202.1|UniProtKB=W5NKV6 W5NKV6 PTHR13390:SF4 LIPASE LIPID DROPLET-ASSOCIATED HYDROLASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 cellular component organization or biogenesis#GO:0071840;cholesterol homeostasis#GO:0042632;chemical homeostasis#GO:0048878;lipid droplet organization#GO:0034389;homeostatic process#GO:0042592;cellular process#GO:0009987;organelle organization#GO:0006996;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043 membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular organelle#GO:0043229 hydrolase#PC00121;lipase#PC00143 LEPOC|Ensembl=ENSLOCG00000014831.1|UniProtKB=W5NCA4 W5NCA4 PTHR11375:SF5 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER E molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;histone binding#GO:0042393;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;binding#GO:0005488 regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016815.1|UniProtKB=W5NJH2 W5NJH2 PTHR24116:SF0 KINASE D-INTERACTING SUBSTRATE OF 220 KDA KINASE D-INTERACTING SUBSTRATE OF 220 KDA enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 response to endogenous stimulus#GO:0009719;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cellular response to nerve growth factor stimulus#GO:1990090;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014931.1|UniProtKB=W5NCN1 W5NCN1 PTHR22951:SF11 CLATHRIN ASSEMBLY PROTEIN PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN phospholipid binding#GO:0005543;SNARE binding#GO:0000149;clathrin binding#GO:0030276;phosphatidylinositol phosphate binding#GO:1901981;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;lipid binding#GO:0008289;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;membrane organization#GO:0061024;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;receptor-mediated endocytosis#GO:0006898 clathrin-coated vesicle#GO:0030136;synaptic membrane#GO:0097060;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;presynapse#GO:0098793;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000010474.1|UniProtKB=W5MWT1 W5MWT1 PTHR16222:SF26 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLHYDROLASE ARH1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009389.1|UniProtKB=W5MSV0 W5MSV0 PTHR23120:SF0 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 1 ISOFORM X1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005953.1|UniProtKB=W5MFN0 W5MFN0 PTHR24412:SF23 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 7 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of small GTPase mediated signal transduction#GO:0051056;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006320.1|UniProtKB=W5MGX0 W5MGX0 PTHR12845:SF10 GUANINE NUCLEOTIDE EXCHANGE FACTOR EPHEXIN-1 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013575.1|UniProtKB=W5N7X6 W5N7X6 PTHR13177:SF3 DEATH-ASSOCIATED PROTEIN 1 DEATH-ASSOCIATED PROTEIN 1 ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 negative regulation of autophagy#GO:0010507;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of catabolic process#GO:0009895;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;negative regulation of translation#GO:0017148;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of gene expression#GO:0010629 LEPOC|Ensembl=ENSLOCG00000014876.1|UniProtKB=W5NCG4 W5NCG4 PTHR47992:SF217 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1B catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of canonical Wnt signaling pathway#GO:0060828 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014541.1|UniProtKB=W5NB93 W5NB93 PTHR13693:SF58 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE, ERYTHROID-SPECIFIC, MITOCHONDRIAL acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;porphyrin-containing compound biosynthetic process#GO:0006779;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000002960.1|UniProtKB=W5M530 W5M530 PTHR24051:SF5 SUSHI DOMAIN-CONTAINING PROTEIN 1 SUSHI DOMAIN-CONTAINING PROTEIN 1 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000010236.1|UniProtKB=W5MVX5 W5MVX5 PTHR10562:SF151 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 1 protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein sumoylation#GO:0016925;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 p53 pathway#P00059>Sumo-1 ligase#P04635 LEPOC|Ensembl=ENSLOCG00000011226.1|UniProtKB=W5MZI0 W5MZI0 PTHR24028:SF307 CADHERIN-87A PROTOCADHERIN GAMMA-C3 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004528.1|UniProtKB=W5MAK8 W5MAK8 PTHR21345:SF9 SPIRE KIND DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;localization#GO:0051179;multicellular organismal reproductive process#GO:0048609;supramolecular fiber organization#GO:0097435;organelle localization#GO:0051640;actin filament-based process#GO:0030029;sexual reproduction#GO:0019953;actin cytoskeleton organization#GO:0030036;reproductive process#GO:0022414;cell cycle#GO:0007049;cell division#GO:0051301;meiotic nuclear division#GO:0140013;establishment of localization#GO:0051234;actin filament organization#GO:0007015;intracellular transport#GO:0046907;transport#GO:0006810;membrane organization#GO:0061024;establishment of spindle localization#GO:0051293;cellular localization#GO:0051641;spindle localization#GO:0051653;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910;nuclear division#GO:0000280;cytokinetic process#GO:0032506;establishment of organelle localization#GO:0051656;gamete generation#GO:0007276;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;meiotic cell cycle#GO:0051321;Golgi vesicle transport#GO:0048193;membrane invagination#GO:0010324;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell cortex#GO:0005938;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000004105.1|UniProtKB=W5M946 W5M946 PTHR15336:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex III#GO:0045275;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012865.1|UniProtKB=W5N5C6 W5N5C6 PTHR22990:SF33 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 10 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of apoptotic process#GO:0042981;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001908.1|UniProtKB=W5M1E6 W5M1E6 PTHR45877:SF4 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Wnt signaling pathway#P00057>SIAH-1#P01433 LEPOC|Ensembl=ENSLOCG00000017843.1|UniProtKB=W5NMT7 W5NMT7 PTHR24225:SF74 CHEMOTACTIC RECEPTOR CHEMERIN-LIKE RECEPTOR 2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;immune response-activating signaling pathway#GO:0002757;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013755.1|UniProtKB=W5N8K5 W5N8K5 PTHR11486:SF67 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 11 protein binding#GO:0005515;channel regulator activity#GO:0016247;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;transporter regulator activity#GO:0141108;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;ion channel regulator activity#GO:0099106;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000005970.1|UniProtKB=W5MFQ5 W5MFQ5 PTHR16234:SF5 SIMILAR TO HYPOTHETICAL PROTEIN FLJ20508 AFG2-INTERACTING RIBOSOME MATURATION FACTOR intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013586.1|UniProtKB=W5N7Z5 W5N7Z5 PTHR12315:SF0 BICOID-INTERACTING PROTEIN RELATED 7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA binding#GO:0003723;snRNA binding#GO:0017069;methyltransferase activity#GO:0008168;binding#GO:0005488;O-methyltransferase activity#GO:0008171;nucleic acid binding#GO:0003676 snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;snRNA metabolic process#GO:0016073;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000015757.1|UniProtKB=W5NFI9 W5NFI9 PTHR24083:SF49 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000012049.1|UniProtKB=W5N2H6 W5N2H6 PTHR12613:SF1 ERO1-RELATED ERO1-LIKE PROTEIN ALPHA oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;signal transduction#GO:0007165;protein maturation#GO:0051604;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;protein folding#GO:0006457;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005594.1|UniProtKB=W5MEE4 W5MEE4 PTHR19143:SF185 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 5 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008744.1|UniProtKB=W5MQJ3 W5MQJ3 PTHR24103:SF611 E3 UBIQUITIN-PROTEIN LIGASE TRIM BBOX AND DUF4200 DOMAIN-CONTAINING PROTEIN-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002172.1|UniProtKB=W5M2C2 W5M2C2 PTHR11347:SF209 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE cyclic-nucleotide phosphodiesterase activity#GO:0004112;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;regulation of cell communication#GO:0010646;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;regulation of cellular process#GO:0050794;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;cyclic nucleotide metabolic process#GO:0009187;regulation of response to stimulus#GO:0048583;nucleotide catabolic process#GO:0009166;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;cGMP metabolic process#GO:0046068;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of cell communication#GO:0010648;nucleotide metabolic process#GO:0009117;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;ribonucleotide metabolic process#GO:0009259;regulation of intracellular signal transduction#GO:1902531;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;negative regulation of biological process#GO:0048519;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000005051.1|UniProtKB=W5MCH1 W5MCH1 PTHR46768:SF1 TWO PORE CALCIUM CHANNEL PROTEIN 2 TWO PORE CHANNEL PROTEIN 2 metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological process involved in interaction with host#GO:0051701;biological regulation#GO:0065007;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;biological process involved in symbiotic interaction#GO:0044403;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722 vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosomal membrane#GO:0005765;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764 ion channel#PC00133 CCKR signaling map#P06959>TPC1/2#P07209 LEPOC|Ensembl=ENSLOCG00000013181.1|UniProtKB=W5N6H8 W5N6H8 PTHR24039:SF48 FIBRILLIN-RELATED CD93 MOLECULE extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000005672.1|UniProtKB=W5MEP0 W5MEP0 PTHR32455:SF1 SPERM ACROSOME-ASSOCIATED PROTEIN 9 SPERM ACROSOME-ASSOCIATED PROTEIN 9 vesicle#GO:0031982;intracellular vesicle#GO:0097708;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;ciliary base#GO:0097546;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;sperm flagellum#GO:0036126;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000000766.1|UniProtKB=W5LXN4 W5LXN4 PTHR46877:SF7 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 8 catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672 cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018093.1|UniProtKB=W5NNI5 W5NNI5 PTHR24229:SF20 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 5 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;binding#GO:0005488 biological regulation#GO:0065007;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of establishment of protein localization#GO:0070201;response to steroid hormone#GO:0048545;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;neuropeptide signaling pathway#GO:0007218;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;cellular response to steroid hormone stimulus#GO:0071383;regulation of localization#GO:0032879;regulation of transport#GO:0051049;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;regulation of insulin secretion#GO:0050796;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of hormone secretion#GO:0046883;regulation of protein localization#GO:0032880;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of protein transport#GO:0051223;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000000255.1|UniProtKB=W5LVX3 W5LVX3 PTHR33769:SF3 TESTIS-EXPRESSED PROTEIN 26 ISOFORM X3 MESENTERIC ESTROGEN-DEPENDENT ADIPOGENESIS PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005130.1|UniProtKB=W5MCR6 W5MCR6 PTHR24414:SF63 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 46 DNA binding#GO:0003677;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000004707.1|UniProtKB=W5MB84 W5MB84 PTHR10985:SF150 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY-RELATED 2 ISOFORM X1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000004447.1|UniProtKB=W5MA99 W5MA99 PTHR24247:SF107 5-HYDROXYTRYPTAMINE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;serotonin binding#GO:0051378;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;signaling receptor activity#GO:0038023;heterocyclic compound binding#GO:1901363;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594 trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014576.1|UniProtKB=W5NBD6 W5NBD6 PTHR13723:SF319 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 4 ISOFORM X1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000014233.1|UniProtKB=W5NA68 W5NA68 PTHR12499:SF30 OPTIC ATROPHY 3 PROTEIN OPA3 OPTIC ATROPHY 3 PROTEIN system process#GO:0003008;multicellular organismal process#GO:0032501;neuromuscular process#GO:0050905;nervous system process#GO:0050877 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016309.1|UniProtKB=W5NHM1 W5NHM1 PTHR24034:SF204 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000018240.1|UniProtKB=W5NNY2 W5NNY2 PTHR24241:SF145 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007181.1|UniProtKB=W5MJY9 W5MJY9 PTHR11422:SF14 T-CELL SURFACE GLYCOPROTEIN CD4 CD4-1 MOLECULE ISOFORM X1 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004331.1|UniProtKB=W5M9W1 W5M9W1 PTHR24338:SF9 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000007216.1|UniProtKB=W5MK25 W5MK25 PTHR46342:SF1 ALPHA-CATULIN ALPHA-CATULIN intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 Wnt signaling pathway#P00057>alpha-catenin#P01471 LEPOC|Ensembl=ENSLOCG00000013059.1|UniProtKB=W5N624 W5N624 PTHR15046:SF2 GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN N-ACETYLNEURAMINYLGALACTOSYLGLUCOSYL-GLUCOSIDE BETA-1,4-N- ACETYLGALACTOSAMINYLTRANSFERASE 2 UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;UDP-N-acetylglucosamine metabolic process#GO:0006047;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040 LEPOC|Ensembl=ENSLOCG00000012280.1|UniProtKB=W5N398 W5N398 PTHR20875:SF8 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6 ISOFORM X1 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000008860.1|UniProtKB=W5MQX4 W5MQX4 PTHR11211:SF16 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000002911.1|UniProtKB=W5M4W1 W5M4W1 PTHR24399:SF14 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 26 transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011726.1|UniProtKB=W5N1B8 W5N1B8 PTHR12461:SF99 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7 dioxygenase activity#GO:0051213;hydrolase activity#GO:0016787;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010522.1|UniProtKB=W5MWY6 W5MWY6 PTHR13202:SF0 MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 1 metabolic process#GO:0008152;protein targeting to ER#GO:0045047;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of protein localization#GO:0045184;establishment of protein localization to endoplasmic reticulum#GO:0072599;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;protein targeting#GO:0006605 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 protein modifying enzyme#PC00260;protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 LEPOC|Ensembl=ENSLOCG00000005819.1|UniProtKB=W5MF71 W5MF71 PTHR46838:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 regulation of lymphocyte migration#GO:2000401;response to bacterium#GO:0009617;positive regulation of biosynthetic process#GO:0009891;regulation of cell motility#GO:2000145;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to external biotic stimulus#GO:0043207;regulation of leukocyte migration#GO:0002685;positive regulation of cytokine production#GO:0001819;regulation of leukocyte cell-cell adhesion#GO:1903037;response to external stimulus#GO:0009605;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;response to other organism#GO:0051707;negative regulation of cell adhesion#GO:0007162;defense response to bacterium#GO:0042742;positive regulation of metabolic process#GO:0009893;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;positive regulation of cell motility#GO:2000147;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;regulation of lymphocyte activation#GO:0051249;response to stress#GO:0006950;regulation of multicellular organismal process#GO:0051239;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;regulation of immune effector process#GO:0002697;negative regulation of multicellular organismal process#GO:0051241;regulation of macromolecule metabolic process#GO:0060255;regulation of T cell proliferation#GO:0042129;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;positive regulation of locomotion#GO:0040017;defense response#GO:0006952;negative regulation of cell activation#GO:0050866;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;regulation of cytokine production#GO:0001817;negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of immune effector process#GO:0002699;regulation of cell adhesion#GO:0030155;regulation of lymphocyte proliferation#GO:0050670;regulation of cytokine production involved in immune response#GO:0002718;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;defense response to Gram-positive bacterium#GO:0050830;positive regulation of multicellular organismal process#GO:0051240;negative regulation of biological process#GO:0048519;response to stimulus#GO:0050896;negative regulation of T cell proliferation#GO:0042130;regulation of leukocyte proliferation#GO:0070663;positive regulation of biological process#GO:0048518;response to biotic stimulus#GO:0009607;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of immune system process#GO:0002684;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;positive regulation of macromolecule metabolic process#GO:0010604 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007431.1|UniProtKB=W5MKW1 W5MKW1 PTHR23115:SF36 TRANSLATION FACTOR G1 TO S PHASE TRANSITION 2 GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;translational termination#GO:0006415;translation#GO:0006412;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000001881.1|UniProtKB=W5M1C4 W5M1C4 PTHR43128:SF33 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 3 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000018292.1|UniProtKB=W5NP34 W5NP34 PTHR11636:SF75 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000001853.1|UniProtKB=W5M188 W5M188 PTHR10985:SF79 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF-LIKE PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of macromolecule biosynthetic process#GO:0010558;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;regulation of gene expression#GO:0010468;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;pattern specification process#GO:0007389;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000017030.1|UniProtKB=W5NK92 W5NK92 PTHR24082:SF197 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 cellular response to chemical stimulus#GO:0070887;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;regulation of lipid metabolic process#GO:0019216;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>PPARalpha/gamma#P06744 LEPOC|Ensembl=ENSLOCG00000009648.1|UniProtKB=W5MTT0 W5MTT0 PTHR14198:SF17 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 20 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000011924.1|UniProtKB=W5N203 W5N203 PTHR12881:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 binding#GO:0005488;transcription regulator activity#GO:0140110;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712 response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to chemical stimulus#GO:0070887;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000010598.1|UniProtKB=W5MX75 W5MX75 PTHR45625:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009654.1|UniProtKB=W5MTT6 W5MTT6 PTHR46053:SF6 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF4-RELATED ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003139.1|UniProtKB=W5M5N8 W5M5N8 PTHR13483:SF11 BOX C_D SNORNA PROTEIN 1-RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;cellular component assembly#GO:0022607;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017426.1|UniProtKB=W5NLM2 W5NLM2 PTHR12649:SF31 PEPTIDYL-TRNA HYDROLASE 2 PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;hydrolase activity#GO:0016787 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;negative regulation of apoptotic process#GO:0043066;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000018178.1|UniProtKB=W5NNS0 W5NNS0 PTHR12365:SF10 SPROUTY PROTEIN SPROUTY HOMOLOG 1 enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 negative regulation of cell communication#GO:0010648;regulation of Ras protein signal transduction#GO:0046578;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of response to stimulus#GO:0048585 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Spry#P00541;FGF signaling pathway#P00021>Spry#P00626;EGF receptor signaling pathway#P00018>SPRY#G01511 LEPOC|Ensembl=ENSLOCG00000015132.1|UniProtKB=W5NDB4 W5NDB4 PTHR32226:SF2 TELO2-INTERACTING PROTEIN 2 TELO2-INTERACTING PROTEIN 2 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000015109.1|UniProtKB=W5ND87 W5ND87 PTHR46849:SF1 RCC1 DOMAIN-CONTAINING PROTEIN 1 RCC1 DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011274.1|UniProtKB=W5MZQ0 W5MZQ0 DACH1 PTHR12577:SF14 DACHSHUND DACHSHUND HOMOLOG 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013829.1|UniProtKB=W5N8U5 W5N8U5 PTHR31997:SF2 AGAP003710-PA PROTEIN FAM149A LEPOC|Ensembl=ENSLOCG00000003732.1|UniProtKB=W5M7T6 W5M7T6 PTHR10075:SF52 BASIGIN RELATED NEXILIN supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cell junction#GO:0030054;I band#GO:0031674;cellular anatomical structure#GO:0110165;organelle#GO:0043226;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000014225.1|UniProtKB=W5NA58 W5NA58 PTHR11769:SF23 HYALURONIDASE HYALURONIDASE-1 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;glycosaminoglycan catabolic process#GO:0006027;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;glycosaminoglycan metabolic process#GO:0030203;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000014934.1|UniProtKB=W5NCM7 W5NCM7 PTHR13058:SF22 THREE PRIME REPAIR EXONUCLEASE 1, 2 EXODEOXYRIBONUCLEASE III hydrolase activity#GO:0016787;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;exonuclease activity#GO:0004527;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017162.1|UniProtKB=W5NKQ5 W5NKQ5 PTHR11767:SF55 INWARD RECTIFIER POTASSIUM CHANNEL KIR6.3 PROTEIN metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000004039.1|UniProtKB=W5M8V9 W5M8V9 PTHR22957:SF682 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SI:CH211-266K8.4 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000001075.1|UniProtKB=W5LYK3 W5LYK3 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010328.1|UniProtKB=W5MW96 W5MW96 PTHR11028:SF6 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324 homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;localization#GO:0051179;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;biological regulation#GO:0065007;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;vacuolar transport#GO:0007034;intracellular transport#GO:0046907 plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;early endosome#GO:0005769;ATPase dependent transmembrane transport complex#GO:0098533;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;endosome#GO:0005768 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000014895.1|UniProtKB=W5NCI2 W5NCI2 PTHR14564:SF3 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT MIC27 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000001342.1|UniProtKB=W5LZJ4 W5LZJ4 PTHR13335:SF1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;TOR signaling#GO:0031929;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;TORC2 signaling#GO:0038203 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;TOR complex#GO:0038201;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017878.1|UniProtKB=W5NMX2 W5NMX2 PTHR20937:SF4 IP14615P MESOGENIN-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;gastrulation#GO:0007369;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;mesoderm morphogenesis#GO:0048332;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;formation of primary germ layer#GO:0001704;mesoderm formation#GO:0001707;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;mesoderm development#GO:0007498;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;anatomical structure formation involved in morphogenesis#GO:0048646;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000001004.1|UniProtKB=W5LYC9 W5LYC9 PTHR47827:SF4 AHD DOMAIN-CONTAINING PROTEIN PROTEIN ENL chromatin binding#GO:0003682;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000012527.1|UniProtKB=W5N478 W5N478 PTHR11801:SF39 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 cell surface receptor signaling pathway via JAK-STAT#GO:0007259;regulation of biosynthetic process#GO:0009889;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to peptide hormone#GO:0043434;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to peptide hormone stimulus#GO:0071375;cell surface receptor signaling pathway#GO:0007166;response to stress#GO:0006950;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway via STAT#GO:0097696;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173;JAK/STAT signaling pathway#P00038>STAT#P01027 LEPOC|Ensembl=ENSLOCG00000007279.1|UniProtKB=W5MKA3 W5MKA3 PTHR46882:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY N MEMBER 1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY N MEMBER 1 phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;response to hypoxia#GO:0001666;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;positive regulation of apoptotic process#GO:0043065;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of apoptotic process#GO:0042981;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;response to abiotic stimulus#GO:0009628;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000017999.1|UniProtKB=W5NN91 W5NN91 PTHR24034:SF204 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000002335.1|UniProtKB=W5M2X7 W5M2X7 PTHR35083:SF2 RGD1565685 PROTEIN CHROMOSOME X OPEN READING FRAME 38 LEPOC|Ensembl=ENSLOCG00000016954.1|UniProtKB=W5NK03 W5NK03 PTHR34034:SF2 PROTEIN FAM180A-RELATED PROTEIN FAM180A LEPOC|Ensembl=ENSLOCG00000017651.1|UniProtKB=W5NM97 W5NM97 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018289.1|UniProtKB=W5NP31 W5NP31 PTHR15405:SF7 PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR 2 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000002058.1|UniProtKB=W5M1X9 W5M1X9 PTHR11390:SF20 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-BETA-1 catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853 DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008828.1|UniProtKB=W5MQT2 W5MQT2 PTHR24240:SF232 OPSIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;cellular response to radiation#GO:0071478;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;signal transduction#GO:0007165;detection of stimulus#GO:0051606;biological regulation#GO:0065007 non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000839.1|UniProtKB=W5LXT1 W5LXT1 PTHR16024:SF15 XK-RELATED PROTEIN XK-RELATED PROTEIN 5 phagocytosis#GO:0006909;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;lipid transport#GO:0006869;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;anatomical structure development#GO:0048856;localization#GO:0051179;programmed cell death#GO:0012501;cell death#GO:0008219;organophosphate ester transport#GO:0015748;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;membrane invagination#GO:0010324;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;cellular process#GO:0009987;endomembrane system organization#GO:0010256;lipid localization#GO:0010876;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;endocytosis#GO:0006897 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000004419.1|UniProtKB=W5MA69 W5MA69 PTHR11850:SF89 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 1 transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;eye development#GO:0001654;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;sensory system development#GO:0048880;embryo development#GO:0009790;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;animal organ development#GO:0048513;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;embryonic organ development#GO:0048568;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 Gonadotropin-releasing hormone receptor pathway#P06664>Pbx1#P06729 LEPOC|Ensembl=ENSLOCG00000009822.1|UniProtKB=W5MUE2 W5MUE2 PTHR10912:SF8 ADP-RIBOSYL CYCLASE ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cyclase#PC00079;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014118.1|UniProtKB=W5N9T6 W5N9T6 PTHR14944:SF3 RPA-RELATED PROTEIN RADX RPA-RELATED PROTEIN RADX DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of response to stress#GO:0080134;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of cellular response to stress#GO:0080135;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;replication fork#GO:0005657 LEPOC|Ensembl=ENSLOCG00000016512.1|UniProtKB=W5NIE0 W5NIE0 PTHR15952:SF11 EXPORTIN-T/LOS1 EXPORTIN-T nucleic acid binding#GO:0003676;binding#GO:0005488;tRNA binding#GO:0000049;RNA binding#GO:0003723 establishment of localization#GO:0051234;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236 nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle envelope#GO:0031967;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014755.1|UniProtKB=W5NC11 W5NC11 PTHR21600:SF40 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD2 catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000007274.1|UniProtKB=W5MKB8 W5MKB8 PTHR11124:SF12 VACUOLAR SORTING PROTEIN VPS29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 29 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907 membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;retromer complex#GO:0030904;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000015338.1|UniProtKB=W5NE24 W5NE24 PTHR45691:SF3 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 2 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 LEPOC|Ensembl=ENSLOCG00000005536.1|UniProtKB=W5ME74 W5ME74 PTHR24248:SF142 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M4 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>mAChR2/4#P01077;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000011204.1|UniProtKB=W5MZJ3 W5MZJ3 PTHR10857:SF51 COPINE COPINE-5 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 response to stimulus#GO:0050896;response to calcium ion#GO:0051592;response to chemical#GO:0042221;response to metal ion#GO:0010038;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000011002.1|UniProtKB=W5MYN8 W5MYN8 PTHR35842:SF1 SI:CH211-67E16.11 SI:CH211-67E16.11 LEPOC|Ensembl=ENSLOCG00000003471.1|UniProtKB=W5M6W4 W5M6W4 PTHR45840:SF4 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 1 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 LEPOC|Ensembl=ENSLOCG00000011401.1|UniProtKB=W5N064 W5N064 DNAAF2 PTHR22997:SF3 PIH1 DOMAIN-CONTAINING PROTEIN 1 PROTEIN KINTOUN cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004952.1|UniProtKB=W5MC42 W5MC42 PTHR24396:SF25 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 644 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000014411.1|UniProtKB=W5NAS9 W5NAS9 PTHR26451:SF882 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002025.1|UniProtKB=W5M1T9 W5M1T9 LSM4 PTHR23338:SF16 SMALL NUCLEAR RIBONUCLEOPROTEIN SM U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM4 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organelle assembly#GO:0070925;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;P-body assembly#GO:0033962;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987;mRNA processing#GO:0006397;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613 U6 snRNP#GO:0005688;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;P-body#GO:0000932;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000005303.1|UniProtKB=W5MDD3 W5MDD3 PTHR10334:SF581 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1 positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of multicellular organismal process#GO:0051240;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011020.1|UniProtKB=W5MYS0 W5MYS0 PTHR45983:SF1 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 22 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;negative regulation of leukocyte cell-cell adhesion#GO:1903038;negative regulation of multicellular organismal process#GO:0051241;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of defense response#GO:0031347;negative regulation of T cell activation#GO:0050868;regulation of immune response#GO:0050776;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;positive regulation of response to stimulus#GO:0048584;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;negative regulation of cell activation#GO:0050866;regulation of innate immune response#GO:0045088;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;response to stimulus#GO:0050896;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;regulation of T cell activation#GO:0050863;regulation of response to external stimulus#GO:0032101;negative regulation of cell-cell adhesion#GO:0022408;antigen receptor-mediated signaling pathway#GO:0050851;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006368.1|UniProtKB=W5MH47 W5MH47 PTHR11533:SF239 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 2 exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;proteolysis#GO:0006508;catabolic process#GO:0009056;primary metabolic process#GO:0044238;peptide catabolic process#GO:0043171;cellular process#GO:0009987 endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005029.1|UniProtKB=W5MCF0 W5MCF0 PTHR23090:SF9 NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;indole-containing compound metabolic process#GO:0042430;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;oxoacid metabolic process#GO:0043436;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000016515.1|UniProtKB=W5NIE6 W5NIE6 RTCB PTHR11118:SF1 RNA-SPLICING LIGASE RTCB HOMOLOG RNA-SPLICING LIGASE RTCB ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 RNA splicing#GO:0008380;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012719.1|UniProtKB=W5N4U0 W5N4U0 PTHR16852:SF2 GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001847.1|UniProtKB=W5M183 W5M183 PTHR18966:SF364 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3B dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268 postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Ionotropic glutamate receptor pathway#P00037>NR3#P01009;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071 LEPOC|Ensembl=ENSLOCG00000009927.1|UniProtKB=W5MUT1 W5MUT1 PTHR11482:SF7 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ANTIZYME INHIBITOR 1 lyase activity#GO:0016829;enzyme regulator activity#GO:0030234;ornithine decarboxylase activity#GO:0004586;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;carboxy-lyase activity#GO:0016831;enzyme activator activity#GO:0008047;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;polyamine metabolic process#GO:0006595;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of catabolic process#GO:0009894;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;amine metabolic process#GO:0009308;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596;negative regulation of protein catabolic process#GO:0042177 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 LEPOC|Ensembl=ENSLOCG00000001202.1|UniProtKB=W5LYZ8 W5LYZ8 PTHR11955:SF96 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, LIVER lipid binding#GO:0008289;fatty acid binding#GO:0005504;organic acid binding#GO:0043177;small molecule binding#GO:0036094;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;binding#GO:0005488;ion binding#GO:0043167 monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000015427.1|UniProtKB=W5NEC9 W5NEC9 PTHR10336:SF29 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ZETA-1 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787;lipase activity#GO:0016298 regulation of biological quality#GO:0065008;sexual reproduction#GO:0019953;cell activation#GO:0001775;positive regulation of cytosolic calcium ion concentration#GO:0007204;biological regulation#GO:0065007;reproductive process#GO:0022414;fertilization#GO:0009566;multicellular organismal process#GO:0032501;cellular process#GO:0009987;single fertilization#GO:0007338 intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 LEPOC|Ensembl=ENSLOCG00000001484.1|UniProtKB=W5LZY5 W5LZY5 PTHR16932:SF39 INTERFERON ALPHA-INDUCIBLE PROTEIN 27 INTERFERON, ALPHA-INDUCIBLE PROTEIN 27-LIKE 2 programmed cell death#GO:0012501;signal transduction#GO:0007165;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell death#GO:0008219;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;intracellular signal transduction#GO:0035556 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007162.1|UniProtKB=W5MJW1 W5MJW1 PTHR11902:SF12 ENOLASE ALPHA-ENOLASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824;phosphopyruvate hydratase activity#GO:0004634 purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975 catalytic complex#GO:1902494;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lyase#PC00144 Glycolysis#P00024>Enolase#P00678 LEPOC|Ensembl=ENSLOCG00000002160.1|UniProtKB=W5M2B4 W5M2B4 PTHR46947:SF1 WD REPEAT-CONTAINING PROTEIN 73 INTEGRATOR COMPLEX ASSEMBLY FACTOR WDR73 supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;spindle pole#GO:0000922 LEPOC|Ensembl=ENSLOCG00000011296.1|UniProtKB=W5MZU1 W5MZU1 PTHR45622:SF5 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC4-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013656.1|UniProtKB=W5N879 W5N879 PTHR47634:SF24 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;signaling#GO:0023052;response to stimulus#GO:0050896;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing, via transesterification reactions#GO:0000375;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000006922.1|UniProtKB=W5MJ19 W5MJ19 PTHR11347:SF108 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4B cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001377.1|UniProtKB=W5LZK2 W5LZK2 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014201.1|UniProtKB=W5NA37 W5NA37 PTHR14383:SF1 SWAP-70 RECOMBINASE PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY D MEMBER 1 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002529.1|UniProtKB=W5M3L9 W5M3L9 PTHR13663:SF2 SIMILAR TO RIKEN CDNA 6430548M08 RIKEN CDNA 6430548M08 GENE LIKE LEPOC|Ensembl=ENSLOCG00000004731.1|UniProtKB=W5MBA8 W5MBA8 PTHR13504:SF34 FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145 PROTEIN ADENYLYLTRANSFERASE FICD hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;protein modification process#GO:0036211;metabolic process#GO:0008152;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 LEPOC|Ensembl=ENSLOCG00000015223.1|UniProtKB=W5NDM6 W5NDM6 PTHR13484:SF8 FIP1-LIKE 1 PROTEIN PRE-MRNA POLYADENYLATION FACTOR FIP1 DOMAIN-CONTAINING PROTEIN mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 LEPOC|Ensembl=ENSLOCG00000013171.1|UniProtKB=W5N6H2 W5N6H2 PTHR10048:SF99 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;glycerophospholipid metabolic process#GO:0006650;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;cell motility#GO:0048870;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000017907.1|UniProtKB=W5NN01 W5NN01 PTHR19268:SF7 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 85-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001686.1|UniProtKB=W5M0Q2 W5M0Q2 PTHR14198:SF18 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016922.1|UniProtKB=W5NJW3 W5NJW3 PTHR21590:SF4 SEA DOMAIN-CONTAINING PROTEIN UPF0606 PROTEIN KIAA1549 LEPOC|Ensembl=ENSLOCG00000013826.1|UniProtKB=W5N8T7 W5N8T7 PTHR24365:SF524 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;toll-like receptor signaling pathway#GO:0002224;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010432.1|UniProtKB=W5MWN5 W5MWN5 PTHR11607:SF69 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 hydrolase#PC00121;glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000011265.1|UniProtKB=W5MZN1 W5MZN1 PTHR24028:SF114 CADHERIN-87A PROTOCADHERIN 1 GAMMA 1 PRECURSOR-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000010765.1|UniProtKB=W5MXT5 W5MXT5 PTHR11360:SF21 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 6 monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017496.1|UniProtKB=W5NLU2 W5NLU2 PTHR23033:SF2 BETA1,3-GALACTOSYLTRANSFERASE C1GALT1-SPECIFIC CHAPERONE 1 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007546.1|UniProtKB=W5ML96 W5ML96 PTHR11576:SF3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA GLYCOPROTEIN 3F, TANDEM DUPLICATE 1 PRECURSOR-RELATED LEPOC|Ensembl=ENSLOCG00000006293.1|UniProtKB=W5MGT9 W5MGT9 PTHR16967:SF1 LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG positive regulation of cell population proliferation#GO:0008284;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 LEPOC|Ensembl=ENSLOCG00000003921.1|UniProtKB=W5M8H8 W5M8H8 PTHR19918:SF3 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG protein-containing complex binding#GO:0044877;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;binding#GO:0005488;enzyme activator activity#GO:0008047 regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of metabolic process#GO:0009893;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;proteasomal protein catabolic process#GO:0010498;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013613.1|UniProtKB=W5N826 W5N826 PTHR19961:SF32 FIMBRIN/PLASTIN PLASTIN-3 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000015410.1|UniProtKB=W5NEA3 W5NEA3 PTHR12378:SF6 DESUMOYLATING ISOPEPTIDASE DEUBIQUITINASE DESI2 catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012283.1|UniProtKB=W5N3A6 W5N3A6 PTHR11711:SF449 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 2 guanyl nucleotide binding#GO:0019001;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 LEPOC|Ensembl=ENSLOCG00000009123.1|UniProtKB=W5MRW7 W5MRW7 PTHR47958:SF24 ATP-DEPENDENT RNA HELICASE DBP3 NUCLEOLAR RNA HELICASE 2-RELATED helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000011529.1|UniProtKB=W5N0K6 W5N0K6 PTHR21029:SF18 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G-PROTEIN SIGNALING 9-BINDING PROTEIN signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000017961.1|UniProtKB=W5NN55 W5NN55 PTHR20884:SF8 GDP-D-GLUCOSE PHOSPHORYLASE 1 GDP-D-GLUCOSE PHOSPHORYLASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;glucose metabolic process#GO:0006006;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000016151.1|UniProtKB=W5NGZ4 W5NGZ4 PTHR13428:SF10 INNER NUCLEAR MEMBRANE PROTEIN MAN1 LEM DOMAIN CONTAINING PROTEIN INNER NUCLEAR MEMBRANE PROTEIN MAN1 DNA binding#GO:0003677;chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;nucleic acid binding#GO:0003676;binding#GO:0005488 membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;membrane assembly#GO:0071709;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000013431.1|UniProtKB=W5N7G1 W5N7G1 PTHR10480:SF2 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG C SNARE binding#GO:0000149;calmodulin binding#GO:0005516;binding#GO:0005488;protein binding#GO:0005515;syntaxin binding#GO:0019905 protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;export from cell#GO:0140352;establishment of organelle localization#GO:0051656;secretion by cell#GO:0032940;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic transmission, glutamatergic#GO:0035249;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;vesicle localization#GO:0051648;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;calcium-ion regulated exocytosis#GO:0017156;establishment of localization#GO:0051234 synaptic membrane#GO:0097060;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular vesicle#GO:0097708;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;axon terminus#GO:0043679;neuromuscular junction#GO:0031594;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;axon#GO:0030424;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;neuron projection terminus#GO:0044306;intracellular membrane-bounded organelle#GO:0043231;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195 Synaptic vesicle trafficking#P05734>Munc13#P05773 LEPOC|Ensembl=ENSLOCG00000004823.1|UniProtKB=W5MBM9 W5MBM9 PTHR24390:SF213 ZINC FINGER PROTEIN MYC-ASSOCIATED ZINC FINGER PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000003954.1|UniProtKB=W5M8L1 W5M8L1 PTHR10772:SF67 10 KDA HEAT SHOCK PROTEIN 10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;protein-folding chaperone binding#GO:0051087;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000004266.1|UniProtKB=W5M9P0 W5M9P0 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000004933.1|UniProtKB=W5MC40 W5MC40 PTHR10546:SF2 SODIUM CHANNEL SUBUNIT BETA-1 AND 3 SODIUM CHANNEL REGULATORY SUBUNIT BETA-1 molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;binding#GO:0005488 regulation of membrane potential#GO:0042391;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;regulation of multicellular organismal process#GO:0051239;cardiac muscle cell action potential involved in contraction#GO:0086002;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;muscle system process#GO:0003012;regulation of biological process#GO:0050789;action potential#GO:0001508;heart process#GO:0003015;sodium ion transport#GO:0006814;muscle contraction#GO:0006936;transport#GO:0006810;regulation of system process#GO:0044057;system process#GO:0003008;heart contraction#GO:0060047;cardiac muscle cell contraction#GO:0086003;establishment of localization#GO:0051234;actin filament-based movement#GO:0030048;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;circulatory system process#GO:0003013;localization#GO:0051179;monoatomic cation transport#GO:0006812;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;regulation of heart contraction#GO:0008016;actin-mediated cell contraction#GO:0070252 sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000012023.1|UniProtKB=W5N2E4 W5N2E4 PTHR24093:SF435 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 4 P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 calcium ion homeostasis#GO:0055074;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cytosolic calcium ion concentration#GO:0051480;homeostatic process#GO:0042592 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000001145.1|UniProtKB=W5LYT5 W5LYT5 PTHR12308:SF40 ANOCTAMIN ANOCTAMIN-10 gated channel activity#GO:0022836;molecular carrier activity#GO:0140104;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;phospholipid scramblase activity#GO:0017128;ligand-gated monoatomic ion channel activity#GO:0015276;lipid carrier activity#GO:0005319;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;intramembrane lipid carrier activity#GO:0140303;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic ion-gated channel activity#GO:0022839;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261 cellular process#GO:0009987;macromolecule localization#GO:0033036;monoatomic ion transmembrane transport#GO:0034220;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;phospholipid transport#GO:0015914;membrane organization#GO:0061024;monoatomic anion transmembrane transport#GO:0098656;lipid transport#GO:0006869;transport#GO:0006810;chloride transport#GO:0006821;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;monoatomic anion transport#GO:0006820;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000014655.1|UniProtKB=W5NBN8 W5NBN8 PTHR11455:SF15 CRYPTOCHROME CRYPTOCHROME-2 anion binding#GO:0043168;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;deoxyribodipyrimidine photo-lyase activity#GO:0003904;ion binding#GO:0043167;DNA binding#GO:0003677;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotide binding#GO:0000166;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097 response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;circadian regulation of gene expression#GO:0032922;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;rhythmic process#GO:0048511;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;response to radiation#GO:0009314;negative regulation of macromolecule metabolic process#GO:0010605;regulation of circadian rhythm#GO:0042752;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;negative regulation of cellular process#GO:0048523;photoperiodism#GO:0009648 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DNA photolyase#PC00014 Circadian clock system#P00015>Cry#P00505;Circadian clock system#P00015>cry#G01501;Circadian clock system#P00015>cry#G01497 LEPOC|Ensembl=ENSLOCG00000003715.1|UniProtKB=W5M7R4 W5M7R4 PTHR21508:SF3 MITOGUARDIN MITOGUARDIN 1 mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;organelle fusion#GO:0048284;cellular process#GO:0009987;cellular component organization#GO:0016043;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996 LEPOC|Ensembl=ENSLOCG00000002652.1|UniProtKB=W5M414 W5M414 MACO1 PTHR47464:SF3 MACOILIN MACOILIN 1B LEPOC|Ensembl=ENSLOCG00000006564.1|UniProtKB=W5MHR7 W5MHR7 PTHR12447:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;plasma membrane#GO:0005886;late endosome#GO:0005770;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014722.1|UniProtKB=W5NBW5 W5NBW5 PTHR11984:SF20 CONNEXIN GAP JUNCTION BETA-1 PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell junction#GO:0030054 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000000925.1|UniProtKB=W5LY28 W5LY28 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007342.1|UniProtKB=W5MKI1 W5MKI1 PTHR13771:SF9 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 1 ISOFORM X1-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004246.1|UniProtKB=W5M9M2 W5M9M2 PTHR32000:SF3 SIMILAR TO HYPOTHETICAL PROTEIN SIMILAR TO HUMAN CHROMOSOME 8 OPEN READING FRAME 34 LEPOC|Ensembl=ENSLOCG00000013030.1|UniProtKB=W5N5Z5 W5N5Z5 PTHR16096:SF8 MICROTUBULE-ASSOCIATED PROTEIN 11 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 14 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012342.1|UniProtKB=W5N3I7 W5N3I7 PTHR11082:SF5 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000012897.1|UniProtKB=W5N5I3 W5N5I3 PTHR10169:SF63 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2 isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;meiosis I#GO:0007127;reciprocal homologous recombination#GO:0140527;cell cycle process#GO:0022402;homologous recombination#GO:0035825;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;sexual reproduction#GO:0019953;reciprocal meiotic recombination#GO:0007131;organelle fission#GO:0048285;organelle organization#GO:0006996;resolution of meiotic recombination intermediates#GO:0000712;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003221.1|UniProtKB=W5M605 W5M605 PTHR11963:SF23 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000009080.1|UniProtKB=W5MRR1 W5MRR1 PTHR11388:SF86 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 3A1 active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;fatty acid transport#GO:0015908;localization#GO:0051179;cellular process#GO:0009987;macromolecule localization#GO:0033036;lipid transport#GO:0006869 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013470.1|UniProtKB=W5N7K8 W5N7K8 PTHR10693:SF10 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;molecular condensate scaffold activity#GO:0140693 cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925 cytosol#GO:0005829;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016527.1|UniProtKB=W5NIF6 W5NIF6 PTHR21477:SF13 ZGC:172139 KIAA0930 LEPOC|Ensembl=ENSLOCG00000011259.1|UniProtKB=W5MZN4 W5MZN4 PTHR47827:SF5 AHD DOMAIN-CONTAINING PROTEIN PROTEIN AF-9 chromatin binding#GO:0003682;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000004822.1|UniProtKB=W5MBM7 W5MBM7 PTHR34344:SF1 UPF0184 PROTEIN C9ORF16 BUBLIN COILED-COIL PROTEIN intermediate filament cytoskeleton organization#GO:0045104;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;intermediate filament bundle assembly#GO:0045110;intermediate filament organization#GO:0045109 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000007715.1|UniProtKB=W5MLW1 W5MLW1 PTHR11638:SF93 ATP-DEPENDENT CLP PROTEASE MITOCHONDRIAL DISAGGREGASE ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular response to stress#GO:0033554;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;cellular response to heat#GO:0034605;response to heat#GO:0009408;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003004.1|UniProtKB=W5M584 W5M584 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006097.1|UniProtKB=W5MG56 W5MG56 PTHR10811:SF7 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE LUNATIC FRINGE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 glycosyltransferase#PC00111;transferase#PC00220 Notch signaling pathway#P00045>Fringe#P01107 LEPOC|Ensembl=ENSLOCG00000016898.1|UniProtKB=W5NJS8 W5NJS8 PTHR23119:SF58 DISCS LARGE LEUCINE-RICH REPEAT-CONTAINING PROTEIN 1 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 protein localization to cell periphery#GO:1990778;intracellular protein transport#GO:0006886;protein localization to synapse#GO:0035418;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;endosomal transport#GO:0016197;cell-cell adhesion#GO:0098609;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;establishment or maintenance of cell polarity#GO:0007163;receptor clustering#GO:0043113;cell adhesion#GO:0007155;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;protein transport#GO:0015031;protein localization to membrane#GO:0072657;endocytic recycling#GO:0032456;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;endosome to plasma membrane protein transport#GO:0099638;cell migration#GO:0016477;biological regulation#GO:0065007;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to cell junction#GO:1902414;establishment or maintenance of bipolar cell polarity#GO:0061245;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;localization#GO:0051179;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;protein localization to plasma membrane#GO:0072659;cell motility#GO:0048870 basolateral plasma membrane#GO:0016323;membrane#GO:0016020;cell-cell junction#GO:0005911;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054;adherens junction#GO:0005912;basal part of cell#GO:0045178;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;anchoring junction#GO:0070161 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018066.1|UniProtKB=W5NNF8 W5NNF8 KCTD8 PTHR14499:SF68 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD8 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;presynaptic active zone#GO:0048786;cell junction#GO:0030054;presynaptic active zone membrane#GO:0048787;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic membrane#GO:0045211 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016269.1|UniProtKB=W5NHG2 W5NHG2 PTHR11875:SF70 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1 LIKE 6 protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005383.1|UniProtKB=W5MDN3 W5MDN3 PTHR18916:SF44 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;organelle organization#GO:0006996;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular component organization#GO:0051130;regulation of microtubule-based process#GO:0032886;supramolecular fiber organization#GO:0097435;regulation of microtubule polymerization#GO:0031113;microtubule cytoskeleton organization#GO:0000226;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;cytoplasmic microtubule organization#GO:0031122;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493 microtubule end#GO:1990752;cell cortex#GO:0005938;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;cell periphery#GO:0071944;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009638.1|UniProtKB=W5MTS1 W5MTS1 PTHR24299:SF56 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1A monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;xenobiotic metabolic process#GO:0006805;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;regulation of biological quality#GO:0065008;steroid catabolic process#GO:0006706;estrogen metabolic process#GO:0008210;lipid catabolic process#GO:0016042;cellular process#GO:0009987;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;cellular response to xenobiotic stimulus#GO:0071466;hormone metabolic process#GO:0042445;response to chemical#GO:0042221;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;secondary metabolic process#GO:0019748 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000003267.1|UniProtKB=W5M650 W5M650 PTHR13806:SF46 FLOTILLIN-RELATED FLOTILLIN-2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010276.1|UniProtKB=W5MW35 W5MW35 PTHR12162:SF0 NIBRIN-RELATED NIBRIN nucleic acid binding#GO:0003676;binding#GO:0005488;damaged DNA binding#GO:0003684;DNA binding#GO:0003677 DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;intracellular signal transduction#GO:0035556;recombinational repair#GO:0000725;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;cellular response to stress#GO:0033554 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000010477.1|UniProtKB=W5MWV0 W5MWV0 PTHR46877:SF12 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 3 transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175 dendrite#GO:0030425;dendritic tree#GO:0097447;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 LEPOC|Ensembl=ENSLOCG00000015647.1|UniProtKB=W5NF53 W5NF53 PTHR24136:SF53 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX CONTAINING 13 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;positive regulation of metabolic process#GO:0009893;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 LEPOC|Ensembl=ENSLOCG00000004757.1|UniProtKB=W5MBE7 W5MBE7 PTHR11749:SF3 RIBULOSE-5-PHOSPHATE-3-EPIMERASE RIBULOSE-PHOSPHATE 3-EPIMERASE ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;D-ribulose-phosphate 3-epimerase activity#GO:0004750;metal ion binding#GO:0046872;cation binding#GO:0043169;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853 nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;NADPH regeneration#GO:0006740;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852 LEPOC|Ensembl=ENSLOCG00000016931.1|UniProtKB=W5NJX1 W5NJX1 PTHR24020:SF90 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXI) CHAIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000011526.1|UniProtKB=W5N0K1 W5N0K1 PTHR12378:SF7 DESUMOYLATING ISOPEPTIDASE DESUMOYLATING ISOPEPTIDASE 1 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;localization#GO:0051179;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cellular localization#GO:0051641;nuclear transport#GO:0051169;regulation of protein catabolic process#GO:0042176;nuclear export#GO:0051168;protein transport#GO:0015031;nucleocytoplasmic transport#GO:0006913;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;protein export from nucleus#GO:0006611;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;regulation of catabolic process#GO:0009894;intracellular transport#GO:0046907;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;intracellular protein transport#GO:0006886;transport#GO:0006810 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000004158.1|UniProtKB=W5M9B7 W5M9B7 PTHR20859:SF85 INTERFERON/INTERLEUKIN RECEPTOR FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003224.1|UniProtKB=W5M606 W5M606 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014125.1|UniProtKB=W5N9U4 W5N9U4 PTHR15454:SF73 NISCHARIN RELATED DYNEIN AXONEMAL LIGHT CHAIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;axoneme assembly#GO:0035082;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012475.1|UniProtKB=W5N3Z9 W5N3Z9 PTHR46198:SF3 PROTEIN-TYROSINE-PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;phosphoprotein phosphatase activity#GO:0004721;protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000012965.1|UniProtKB=W5N5R8 W5N5R8 PTHR14159:SF0 ATAXIN-3-RELATED ATAXIN-3-RELATED ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of TORC1 signaling#GO:1904262;negative regulation of biological process#GO:0048519;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;regulation of cellular response to stress#GO:0080135;negative regulation of cell communication#GO:0010648;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of TORC1 signaling#GO:1903432;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of response to endoplasmic reticulum stress#GO:1905897;negative regulation of TOR signaling#GO:0032007;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of ERAD pathway#GO:1904292;regulation of cell communication#GO:0010646;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006150.1|UniProtKB=W5MGB8 W5MGB8 PTHR24347:SF461 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE 2, SKELETAL_CARDIAC MUSCLE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 animal gross anatomical part developmental process#GO:0160108;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;heart development#GO:0007507;muscle tissue development#GO:0060537;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;tissue morphogenesis#GO:0048729;cellular response to stimulus#GO:0051716;heart morphogenesis#GO:0003007;striated muscle contraction#GO:0006941;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;muscle contraction#GO:0006936;developmental process#GO:0032502;system process#GO:0003008;cardiac muscle tissue development#GO:0048738;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;tissue development#GO:0009888 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000008916.1|UniProtKB=W5MR52 W5MR52 PTHR11753:SF12 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-3 COMPLEX SUBUNIT SIGMA-1 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009022.1|UniProtKB=W5MRI2 W5MRI2 PTHR17068:SF12 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MARVEL DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003379.1|UniProtKB=W5M6I8 W5M6I8 PTHR20914:SF50 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 PHOSPHOLIPASE A2 INHIBITOR AND LY6_PLAUR DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016091.1|UniProtKB=W5NGR4 W5NGR4 PTHR21501:SF6 PROTEIN FAM-161 PROTEIN FAM161A-RELATED cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cilium organization#GO:0044782;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840 LEPOC|Ensembl=ENSLOCG00000015655.1|UniProtKB=W5NF63 W5NF63 PTHR11070:SF30 UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER F-BOX DNA HELICASE 1 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678 nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016754.1|UniProtKB=W5NJA0 W5NJA0 PTHR47437:SF2 JNK-INTERACTING PROTEIN 1-LIKE PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 2 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;kinase binding#GO:0019900;structural molecule activity#GO:0005198;MAP kinase scaffold activity#GO:0005078;protein complex scaffold activity#GO:0140378;molecular adaptor activity#GO:0060090 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000018144.1|UniProtKB=W5NNN6 W5NNN6 PTHR10666:SF451 UBIQUITIN ISG15 UBIQUITIN-LIKE MODIFIER structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;nucleus#GO:0005634;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002319.1|UniProtKB=W5M2V7 W5M2V7 PTHR14308:SF0 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 regulation of biological process#GO:0050789;regulation of growth#GO:0040008;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cell growth#GO:0001558;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000721.1|UniProtKB=W5LXE1 W5LXE1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015240.1|UniProtKB=W5NDP4 W5NDP4 PTHR17098:SF2 NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015004.1|UniProtKB=W5NCW5 W5NCW5 PTHR10555:SF129 SORTING NEXIN SORTING NEXIN-1 binding#GO:0005488;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;retromer complex#GO:0030904;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009548.1|UniProtKB=W5MTG1 W5MTG1 PTHR10792:SF1 60S RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN EL24 RNA binding#GO:0003723;structural molecule activity#GO:0005198;mRNA binding#GO:0003729;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000005378.1|UniProtKB=W5MDM8 W5MDM8 PTHR11587:SF2 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ligase#PC00142;metabolite interconversion enzyme#PC00262 Arginine biosynthesis#P02728>Argininosuccinate synthase#P02840 LEPOC|Ensembl=ENSLOCG00000001528.1|UniProtKB=W5M038 W5M038 PTHR10024:SF252 SYNAPTOTAGMIN SYNAPTOTAGMIN-12 protein binding#GO:0005515;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular process#GO:0009987;regulation of cellular process#GO:0050794;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;transport#GO:0006810;regulation of secretion#GO:0051046;localization#GO:0051179;establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000011083.1|UniProtKB=W5MYZ9 W5MYZ9 PTHR14255:SF4 CEREBLON PROTEIN CEREBLON ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stimulus#GO:0048583;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012428.1|UniProtKB=W5N3U3 W5N3U3 PTHR24270:SF5 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 4 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transfer/carrier protein#PC00219;apolipoprotein#PC00052 Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173 LEPOC|Ensembl=ENSLOCG00000005865.1|UniProtKB=W5MFC7 W5MFC7 PTHR11567:SF25 ACID PHOSPHATASE-RELATED PROTEIN FRA10AC1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000009111.1|UniProtKB=W5MRV2 W5MRV2 PTHR23250:SF3 DYSFERLIN-RELATED FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000017865.1|UniProtKB=W5NMV9 W5NMV9 PTHR31655:SF3 PROTEIN FAM78A PROTEIN FAM78A LEPOC|Ensembl=ENSLOCG00000001718.1|UniProtKB=W5M0T3 W5M0T3 PTHR11532:SF43 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE X1-RELATED metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001367.1|UniProtKB=W5LZJ8 W5LZJ8 FZR1 PTHR19918:SF34 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;binding#GO:0005488;enzyme activator activity#GO:0008047 regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;primary metabolic process#GO:0044238;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732 nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011943.1|UniProtKB=W5N230 W5N230 PTHR46538:SF1 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000010864.1|UniProtKB=W5MY74 W5MY74 PTHR11219:SF8 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell adhesion#GO:0007155;neuron development#GO:0048666;axonogenesis#GO:0007409;synaptic membrane adhesion#GO:0099560;axon guidance#GO:0007411;axon development#GO:0061564;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell junction organization#GO:0034330;synapse organization#GO:0050808;anatomical structure development#GO:0048856;system development#GO:0048731 cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202 LEPOC|Ensembl=ENSLOCG00000000577.1|UniProtKB=W5LWY1 W5LWY1 PTHR24020:SF86 COLLAGEN ALPHA COLLAGEN TYPE VI ALPHA 6 CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000013844.1|UniProtKB=W5N8X1 W5N8X1 PTHR10183:SF440 CALPAIN CALPAIN 6 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001065.1|UniProtKB=W5LYJ0 W5LYJ0 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005036.1|UniProtKB=W5MCH2 W5MCH2 PTHR24153:SF14 ESPIN ESPIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cell projection organization#GO:0030030;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017 stereocilium#GO:0032420;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000004775.1|UniProtKB=W5MBI3 W5MBI3 PTHR45819:SF1 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000002119.1|UniProtKB=W5M263 W5M263 PTHR24031:SF761 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX49-RELATED ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001685.1|UniProtKB=W5M0S5 W5M0S5 PTHR24006:SF722 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 48 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012496.1|UniProtKB=W5N430 W5N430 PTHR24240:SF72 OPSIN MELANOPSIN signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;signal transduction#GO:0007165;regulation of circadian rhythm#GO:0042752;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001098.1|UniProtKB=W5LYQ0 W5LYQ0 PTHR10569:SF2 GLYCOGEN DEBRANCHING ENZYME GLYCOGEN DEBRANCHING ENZYME hydrolase activity#GO:0016787;glucosidase activity#GO:0015926;alpha-glucosidase activity#GO:0090599;hydrolase activity, acting on glycosyl bonds#GO:0016798;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;transferase activity#GO:0016740;catalytic activity#GO:0003824 energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;generation of precursor metabolites and energy#GO:0006091;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular process#GO:0009987;glycogen catabolic process#GO:0005980;carbohydrate catabolic process#GO:0016052;energy reserve metabolic process#GO:0006112;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977 LEPOC|Ensembl=ENSLOCG00000003272.1|UniProtKB=W5M669 W5M669 PTHR23316:SF3 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-5 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;NLS-bearing protein import into nucleus#GO:0006607;cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;synaptic signaling#GO:0099536;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003164.1|UniProtKB=W5M5S9 W5M5S9 PTHR21382:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012393.1|UniProtKB=W5N3Q8 W5N3Q8 PTHR45747:SF20 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) [HISTONE H3]-LYSINE(27) N-TRIMETHYLTRANSFERASE histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;binding#GO:0005488;N-methyltransferase activity#GO:0008170;chromatin binding#GO:0003682;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276 biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000010708.1|UniProtKB=W5MXL4 W5MXL4 PTHR42753:SF9 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN ML39 catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000016178.1|UniProtKB=W5NH27 W5NH27 PTHR10414:SF47 ETHANOLAMINEPHOSPHOTRANSFERASE ETHANOLAMINEPHOSPHOTRANSFERASE 1 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000013368.1|UniProtKB=W5N765 W5N765 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007926.1|UniProtKB=W5MML4 W5MML4 PTHR22779:SF4 SD17342P TRANSMEMBRANE PROTEIN 170B regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004135.1|UniProtKB=W5M982 W5M982 PTHR12902:SF7 WASP-1 ACTIN-BINDING PROTEIN WASF3 protein kinase A regulatory subunit binding#GO:0034237;binding#GO:0005488;protein kinase A binding#GO:0051018;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;cellular component organization or biogenesis#GO:0071840;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029 intracellular anatomical structure#GO:0005622;lamellipodium#GO:0030027;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000007192.1|UniProtKB=W5MJZ5 W5MJZ5 PTHR11232:SF76 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER CARBOXYL-TERMINAL PDZ LIGAND OF NEURONAL NITRIC OXIDE SYNTHASE PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014384.1|UniProtKB=W5NAQ6 W5NAQ6 PTHR23257:SF727 SERINE-THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006004.1|UniProtKB=W5MFU7 W5MFU7 PTHR22406:SF2 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM SLAIN MOTIF-CONTAINING PROTEIN 1 regulation of cellular component organization#GO:0051128;cytoplasmic microtubule organization#GO:0031122;regulation of cellular component biogenesis#GO:0044087;microtubule nucleation#GO:0007020;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;protein polymerization#GO:0051258;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of organelle organization#GO:0033043;positive regulation of organelle organization#GO:0010638;regulation of microtubule polymerization#GO:0031113;positive regulation of cellular component organization#GO:0051130;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of microtubule-based process#GO:0032886;positive regulation of protein polymerization#GO:0032273;biological regulation#GO:0065007;microtubule polymerization or depolymerization#GO:0031109;positive regulation of cellular process#GO:0048522;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule polymerization#GO:0046785 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;microtubule end#GO:1990752;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000009756.1|UniProtKB=W5MU69 W5MU69 PTHR13817:SF49 TITIN MYOSIN-BINDING PROTEIN H structural molecule activity#GO:0005198 striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;contractile muscle fiber#GO:0043292;A band#GO:0031672;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular organelle#GO:0043229;M band#GO:0031430 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000007854.1|UniProtKB=W5MMC4 W5MMC4 PTHR31463:SF4 MACROPHAGE-EXPRESSED GENE 1 PROTEIN MACROPHAGE-EXPRESSED GENE 1 PROTEIN response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952 LEPOC|Ensembl=ENSLOCG00000007430.1|UniProtKB=W5MKY0 W5MKY0 PTHR45627:SF11 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 6 cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;cyclic nucleotide biosynthetic process#GO:0009190;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 adenylate cyclase#PC00043 GABA-B receptor II signaling#P05731>AC#P05760;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841 LEPOC|Ensembl=ENSLOCG00000010388.1|UniProtKB=W5MWI6 W5MWI6 PTHR45945:SF1 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G PROTEIN SIGNALING 12 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000014778.1|UniProtKB=W5NC42 W5NC42 PTHR14944:SF4 RPA-RELATED PROTEIN RADX RPA-RELATED PROTEIN RADX DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697 regulation of cellular response to stress#GO:0080135;regulation of response to stress#GO:0080134;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;replication fork#GO:0005657;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000006211.1|UniProtKB=W5MGJ2 W5MGJ2 PTHR28541:SF1 DDB1- AND CUL4-ASSOCIATED FACTOR 15 DDB1- AND CUL4-ASSOCIATED FACTOR 15 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 LEPOC|Ensembl=ENSLOCG00000012056.1|UniProtKB=W5N2G6 W5N2G6 PTHR10740:SF10 TRANSFORMING GROWTH FACTOR ALPHA EPIGEN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell cycle#GO:0051726;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;positive regulation of organelle organization#GO:0010638;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of cellular component organization#GO:0051130;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;regulation of nuclear division#GO:0051783;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;ERBB signaling pathway#GO:0038127;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of mitotic nuclear division#GO:0007088;positive regulation of mitotic nuclear division#GO:0045840;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000004093.1|UniProtKB=W5M940 W5M940 PTHR43272:SF13 LONG-CHAIN-FATTY-ACID--COA LIGASE FATTY ACID COA LIGASE ACSL3 ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;oxoacid metabolic process#GO:0043436;animal gross anatomical part developmental process#GO:0160108;nucleoside phosphate metabolic process#GO:0006753;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing compound metabolic process#GO:0006139;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;sulfur compound metabolic process#GO:0006790 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;lipid droplet#GO:0005811;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000011214.1|UniProtKB=W5MZG5 W5MZG5 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune system process#GO:0002376;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;immune response#GO:0006955;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015529.1|UniProtKB=W5NEQ4 W5NEQ4 PTHR24393:SF151 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 956 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000009874.1|UniProtKB=W5MUK9 W5MUK9 PTHR21292:SF4 EXOCYST COMPLEX COMPONENT SEC6-RELATED TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940 intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;cell periphery#GO:0071944;cell cortex#GO:0005938;exocyst#GO:0000145;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006579.1|UniProtKB=W5MHU8 W5MHU8 PTHR11036:SF135 SEMAPHORIN SEMAPHORIN-4E binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to chemical#GO:0042221;taxis#GO:0042330;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;chemotaxis#GO:0006935;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;locomotion#GO:0040011 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000006396.1|UniProtKB=W5MH66 W5MH66 PTHR24409:SF330 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 521 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013140.1|UniProtKB=W5N6C2 W5N6C2 PTHR10671:SF7 EPITHELIAL MEMBRANE PROTEIN-RELATED PERIPHERAL MYELIN PROTEIN 22 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006069.1|UniProtKB=W5MG19 W5MG19 PTHR10609:SF14 BIOTINIDASE-RELATED BIOTINIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 biotin metabolic process#GO:0006768;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003280.1|UniProtKB=W5M664 W5M664 PTHR13399:SF2 TRANSLOCON-ASSOCIATED PROTEIN TRAP , GAMMA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT GAMMA cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000002384.1|UniProtKB=W5M339 W5M339 PTHR15348:SF1 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013475.1|UniProtKB=W5N7K5 W5N7K5 PTHR23350:SF4 PEROXISOME ASSEMBLY PROTEIN 10 PEROXISOME BIOGENESIS FACTOR 2 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013075.1|UniProtKB=W5N653 W5N653 MCM7 PTHR11630:SF26 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM7 helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697 DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA replication initiation#GO:0006270;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;MCM complex#GO:0042555;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014100.1|UniProtKB=W5N9R3 W5N9R3 PTHR15222:SF2 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006641.1|UniProtKB=W5MI12 W5MI12 PTHR22504:SF5 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899 negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009418.1|UniProtKB=W5MSY1 W5MSY1 PTHR12297:SF22 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A, MITOCHONDRIAL-LIKE cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003771.1|UniProtKB=W5M806 W5M806 PTHR44167:SF39 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED SERINE_THREONINE-PROTEIN KINASE CHK2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA integrity checkpoint signaling#GO:0031570;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>Chk2#P01484 LEPOC|Ensembl=ENSLOCG00000008881.1|UniProtKB=W5MR01 W5MR01 PTHR47979:SF8 DRAB11-RELATED RAS-RELATED PROTEIN RAB-25 nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234 recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000013356.1|UniProtKB=W5N751 W5N751 PTHR12015:SF198 SMALL INDUCIBLE CYTOKINE A INTERLEUKIN-8 cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 response to lipopolysaccharide#GO:0032496;neutrophil chemotaxis#GO:0030593;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;taxis#GO:0042330;neutrophil migration#GO:1990266;cellular response to lipid#GO:0071396;granulocyte migration#GO:0097530;defense response to other organism#GO:0098542;response to lipid#GO:0033993;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;response to oxygen-containing compound#GO:1901700;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to molecule of bacterial origin#GO:0002237;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;leukocyte migration#GO:0050900;cell migration#GO:0016477;response to other organism#GO:0051707;immune response#GO:0006955;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;response to bacterium#GO:0009617;inflammatory response#GO:0006954;chemotaxis#GO:0006935;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 CCKR signaling map#P06959>IL8#G07296;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856;CCKR signaling map#P06959>IL8#G07001;CCKR signaling map#P06959>IL8#P07136;Interleukin signaling pathway#P00036>Interleukin#P00970 LEPOC|Ensembl=ENSLOCG00000013912.1|UniProtKB=W5N946 W5N946 PTHR43243:SF35 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;amino acid transporter#PC00046 LEPOC|Ensembl=ENSLOCG00000015673.1|UniProtKB=W5NF84 W5NF84 PTHR23214:SF3 NEUROFILAMENT TRIPLET H PROTEIN NEUROFILAMENT MEDIUM structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;intermediate filament organization#GO:0045109;intermediate filament bundle assembly#GO:0045110;intermediate filament-based process#GO:0045103 LEPOC|Ensembl=ENSLOCG00000011324.1|UniProtKB=W5MZV7 W5MZV7 PTHR19143:SF444 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-3 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010509.1|UniProtKB=W5MWX0 W5MWX0 PTHR46361:SF5 ELECTRON CARRIER/ PROTEIN DISULFIDE OXIDOREDUCTASE DEP DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012692.1|UniProtKB=W5N4Q8 W5N4Q8 PTHR31940:SF2 SMALL KINETOCHORE-ASSOCIATED PROTEIN SMALL KINETOCHORE-ASSOCIATED PROTEIN microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;nuclear division#GO:0000280;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996 microtubule#GO:0005874;supramolecular fiber#GO:0099512;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriolar satellite#GO:0034451;mitotic spindle#GO:0072686;chromosome#GO:0005694;kinetochore#GO:0000776;microtubule end#GO:1990752;microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779 LEPOC|Ensembl=ENSLOCG00000005420.1|UniProtKB=W5MDS7 W5MDS7 PTHR12840:SF1 NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016421.1|UniProtKB=W5NI24 W5NI24 PTHR32122:SF1 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT A TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT A General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>SL1 complex#P00653 LEPOC|Ensembl=ENSLOCG00000015972.1|UniProtKB=W5NGA8 W5NGA8 PTHR11135:SF0 HISTONE ACETYLTRANSFERASE-RELATED ELONGATOR COMPLEX PROTEIN 3 nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;elongator holoenzyme complex#GO:0033588;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010272.1|UniProtKB=W5MW22 W5MW22 PTHR13832:SF305 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1J hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000017354.1|UniProtKB=W5NLF0 W5NLF0 PTHR46617:SF1 FORKHEAD BOX PROTEIN G1 FORKHEAD BOX PROTEIN G1 binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000012203.1|UniProtKB=W5N305 W5N305 PTHR24240:SF55 OPSIN OPSIN 5-LIKE 1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;detection of stimulus#GO:0051606;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;signaling#GO:0023052;cellular response to radiation#GO:0071478 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009809.1|UniProtKB=W5MUD0 W5MUD0 PTHR12570:SF16 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED NIPA-LIKE PROTEIN 2 monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;magnesium ion transport#GO:0015693 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000007969.1|UniProtKB=W5MMR8 W5MMR8 PTHR14273:SF0 LYR MOTIF-CONTAINING PROTEIN 1 LYR MOTIF-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017867.1|UniProtKB=W5NMW1 W5NMW1 PTHR22639:SF13 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3-LIKE viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000002079.1|UniProtKB=W5M204 W5M204 PTHR24064:SF198 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000017158.1|UniProtKB=W5NKP8 W5NKP8 PTHR11071:SF585 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 6-RELATED chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011129.1|UniProtKB=W5MZ69 W5MZ69 PTHR24055:SF110 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 14 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>p38#P00644;EGF receptor signaling pathway#P00018>p38#P00562;B cell activation#P00010>p38#P00384;TGF-beta signaling pathway#P00052>P38#P01275;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;VEGF signaling pathway#P00056>p38MAPK#P01423;JAK/STAT signaling pathway#P00038>Serine kinase#P01029;Parkinson disease#P00049>p38 MAPK#P01212;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Oxidative stress response#P00046>p38#P01135;p38 MAPK pathway#P05918>p38alpha#P06031;CCKR signaling map#P06959>p38MAPK#P07079;Toll receptor signaling pathway#P00054>p38#P01352;Angiogenesis#P00005>p38MAPK#P00182;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;CCKR signaling map#P06959>MAPKAP-K2#P07217;Ras Pathway#P04393>p38#P04558 LEPOC|Ensembl=ENSLOCG00000001258.1|UniProtKB=W5LZ69 W5LZ69 PTHR15168:SF0 CYTOCHROME B-245 LIGHT CHAIN CYTOCHROME B-245 LIGHT CHAIN oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;catalytic activity#GO:0003824 superoxide metabolic process#GO:0006801;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;cellular process#GO:0009987;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 LEPOC|Ensembl=ENSLOCG00000017024.1|UniProtKB=W5NK82 W5NK82 PTHR10157:SF42 DOPAMINE BETA HYDROXYLASE RELATED DBH-LIKE MONOOXYGENASE PROTEIN 1 HOMOLOG oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;extracellular region#GO:0005576;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000011261.1|UniProtKB=W5MZN0 W5MZN0 PTHR12422:SF3 GH09096P CYFIP-RELATED RAC1 INTERACTOR B positive regulation of cell activation#GO:0050867;regulation of multicellular organismal process#GO:0051239;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of T cell activation#GO:0050863;regulation of cell adhesion#GO:0030155;positive regulation of T cell activation#GO:0050870;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of leukocyte activation#GO:0002696;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of lymphocyte activation#GO:0051249;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell adhesion#GO:0045785;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;positive regulation of lymphocyte activation#GO:0051251 LEPOC|Ensembl=ENSLOCG00000013818.1|UniProtKB=W5N8T4 W5N8T4 PTHR14167:SF130 SH3 DOMAIN-CONTAINING SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 2 ISOFORM X1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018147.1|UniProtKB=W5NNN9 W5NNN9 PTHR24225:SF81 CHEMOTACTIC RECEPTOR CHEMERIN-LIKE RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000336.1|UniProtKB=W5LW56 W5LW56 PTHR10903:SF112 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000016674.1|UniProtKB=W5NIY9 W5NIY9 PTHR10177:SF66 CYCLINS G1_S-SPECIFIC CYCLIN-D2 protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;positive regulation of cellular process#GO:0048522;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of cell cycle G1/S phase transition#GO:1902808;G1/S transition of mitotic cell cycle#GO:0000082 microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;transferase complex#GO:1990234;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 PI3 kinase pathway#P00048>Cyclin d#G01546;Cell cycle#P00013>Cyclin D#P00484 LEPOC|Ensembl=ENSLOCG00000016883.1|UniProtKB=W5NJR0 W5NJR0 PTHR12414:SF9 GLIAL CELLS MISSING RELATED/GLIDE GLIAL CELLS MISSING HOMOLOG 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;gliogenesis#GO:0042063;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000011864.1|UniProtKB=W5N1S9 W5N1S9 PTHR34221:SF4 HYPOTHETICAL PROTEIN LOC691189 CHROMOSOME LG9 OPEN READING FRAME, HUMAN C17ORF98 LEPOC|Ensembl=ENSLOCG00000002814.1|UniProtKB=W5M4K3 W5M4K3 PTHR45762:SF1 ZINC FINGER RNA-BINDING PROTEIN SPERMATID PERINUCLEAR RNA-BINDING PROTEIN single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005852.1|UniProtKB=W5MFA5 W5MFA5 PTHR23277:SF69 NECTIN-RELATED NECTIN-1 virus receptor activity#GO:0001618;protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;macromolecule localization#GO:0033036;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to cell junction#GO:1902414;cell adhesion#GO:0007155 apical junction complex#GO:0043296;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha#P00160;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha N-terminal fragment#P00164;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha C-terminal fragment#P00177;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha transmembrane fragment#P00134;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha intracellular fragment#P00159 LEPOC|Ensembl=ENSLOCG00000007160.1|UniProtKB=W5MJV7 W5MJV7 PTHR14898:SF6 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB HOMOLOG 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014551.1|UniProtKB=W5NBA3 W5NBA3 PTHR45689:SF4 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 4 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215 monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000010430.1|UniProtKB=W5MWQ2 W5MWQ2 PTHR46877:SF10 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 6 transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012302.1|UniProtKB=W5N3C8 W5N3C8 PTHR13475:SF4 NEUGRIN NEUGRIN cellular component organization or biogenesis#GO:0071840;mitochondrial ribosome assembly#GO:0061668;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000005053.1|UniProtKB=W5MCH3 W5MCH3 PTHR13084:SF5 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 4 regulation of biological process#GO:0050789;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of transport#GO:0051049 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016731.1|UniProtKB=W5NJ64 W5NJ64 PTHR15926:SF1 ALL-TRANS RETINOIC ACID-INDUCED DIFFERENTIATION FACTOR ALL-TRANS RETINOIC ACID-INDUCED DIFFERENTIATION FACTOR LEPOC|Ensembl=ENSLOCG00000008942.1|UniProtKB=W5MR83 W5MR83 PTHR12081:SF44 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F3 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 p53 pathway feedback loops 2#P04398>E2F-1#P04652;p53 pathway#P00059>E2F-1#P04627;Cell cycle#P00013>E2F#P00488 LEPOC|Ensembl=ENSLOCG00000008400.1|UniProtKB=W5MP99 W5MP99 PTHR15740:SF2 NEUROPROTECTIVE PEPTIDE-CONTAINING PROTEIN ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN 2 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000016024.1|UniProtKB=W5NGH6 W5NGH6 PTHR15341:SF3 SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D DNA binding#GO:0003677;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000007688.1|UniProtKB=W5MLT5 W5MLT5 PTHR11705:SF20 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE B metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000005007.1|UniProtKB=W5MCB8 W5MCB8 PTHR46252:SF4 BRORIN FAMILY MEMBER BRORIN regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of BMP signaling pathway#GO:0030510;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;extracellular region#GO:0005576;signaling receptor complex#GO:0043235 LEPOC|Ensembl=ENSLOCG00000001706.1|UniProtKB=W5M0S7 W5M0S7 PTHR21646:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein stability#GO:0031647;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000003785.1|UniProtKB=W5M809 W5M809 PTHR10571:SF0 UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000003700.1|UniProtKB=W5M7N9 W5M7N9 PTHR46013:SF9 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000007358.1|UniProtKB=W5MKL1 W5MKL1 PTHR11668:SF525 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of circadian rhythm#GO:0042752;regulation of biological process#GO:0050789;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein phosphatase#PC00195 Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969;Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602 LEPOC|Ensembl=ENSLOCG00000003144.1|UniProtKB=W5M5Q1 W5M5Q1 PTHR16441:SF10 FIDIPIDINE COILED-COIL DOMAIN-CONTAINING PROTEIN 93 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000000581.1|UniProtKB=W5LWY9 W5LWY9 PTHR19846:SF0 WD40 REPEAT PROTEIN U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP4 RNA processing factor#PC00147;RNA splicing factor#PC00148 mRNA splicing#P00058>U6#P01473;mRNA splicing#P00058>U4#P01476 LEPOC|Ensembl=ENSLOCG00000002745.1|UniProtKB=W5M4C5 W5M4C5 PTHR24343:SF569 SERINE/THREONINE KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001543.1|UniProtKB=W5M059 W5M059 PTHR22420:SF5 PROTEIN FAM81A PROTEIN FAM81B LEPOC|Ensembl=ENSLOCG00000012497.1|UniProtKB=W5N433 W5N433 PTHR45867:SF3 PURPLE ACID PHOSPHATASE ACID PHOSPHATASE TYPE 7 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000009989.1|UniProtKB=W5MV06 W5MV06 PTHR44489:SF11 FAMILY NOT NAMED WD REPEAT DOMAIN 86 LEPOC|Ensembl=ENSLOCG00000003535.1|UniProtKB=W5M723 W5M723 PTHR43918:SF5 ACETYLCHOLINESTERASE CHOLINESTERASE catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 LEPOC|Ensembl=ENSLOCG00000007240.1|UniProtKB=W5MK53 W5MK53 PTHR10657:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005396.1|UniProtKB=W5MDP6 W5MDP6 PTHR22442:SF3 FAMILY NOT NAMED SOLUBLE LAMIN-ASSOCIATED PROTEIN OF 75 KDA LEPOC|Ensembl=ENSLOCG00000014718.1|UniProtKB=W5NBW0 W5NBW0 PTHR11202:SF12 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER VASODILATOR-STIMULATED PHOSPHOPROTEIN binding#GO:0005488;protein binding#GO:0005515 axon guidance#GO:0007411;positive regulation of cellular process#GO:0048522;actin polymerization or depolymerization#GO:0008154;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;neuron projection morphogenesis#GO:0048812;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of cellular process#GO:0050794;actin filament-based process#GO:0030029;embryo development ending in birth or egg hatching#GO:0009792;anatomical structure development#GO:0048856;organelle organization#GO:0006996;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;nervous system development#GO:0007399;embryo development#GO:0009790;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of anatomical structure size#GO:0090066;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;regulation of actin filament length#GO:0030832;neuron development#GO:0048666;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;axon development#GO:0061564;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;tissue development#GO:0009888;regulation of actin polymerization or depolymerization#GO:0008064;plasma membrane bounded cell projection organization#GO:0120036;tube development#GO:0035295;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of supramolecular fiber organization#GO:1902903;tube morphogenesis#GO:0035239;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;tissue morphogenesis#GO:0048729;system development#GO:0048731;supramolecular fiber organization#GO:0097435;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;plasma membrane bounded cell projection morphogenesis#GO:0120039;embryonic morphogenesis#GO:0048598;cell projection morphogenesis#GO:0048858;morphogenesis of an epithelium#GO:0002009;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;cell differentiation#GO:0030154;cell projection organization#GO:0030030;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;cell junction#GO:0030054;anchoring junction#GO:0070161 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>VASP#P00934;Axon guidance mediated by netrin#P00009>Ena#P00361;Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516 LEPOC|Ensembl=ENSLOCG00000012992.1|UniProtKB=W5N5U1 W5N5U1 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 aminoglycan biosynthetic process#GO:0006023;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000012882.1|UniProtKB=W5N5F0 W5N5F0 PTHR22461:SF1 SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2-RELATED SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000015674.1|UniProtKB=W5NF86 W5NF86 PTHR10338:SF62 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H5 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007088.1|UniProtKB=W5MJP5 W5MJP5 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER PANCREATIC ELASTASE serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010281.1|UniProtKB=W5MW29 W5MW29 PTHR24072:SF100 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOC pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 biological regulation#GO:0065007;cell migration#GO:0016477;actin filament organization#GO:0007015;mitotic cell cycle process#GO:1903047;regulation of actin filament-based process#GO:0032970;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;cell motility#GO:0048870;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;cell division#GO:0051301;cell cycle#GO:0007049;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910 cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 small GTPase#PC00208;G-protein#PC00020 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507;Angiogenesis#P00005>GTPase#P00254;Integrin signalling pathway#P00034>Rho#P00948;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Ras Pathway#P04393>Rho#P04578;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Axon guidance mediated by semaphorins#P00007>Rho#P00341 LEPOC|Ensembl=ENSLOCG00000003606.1|UniProtKB=W5M7B8 W5M7B8 PTHR10997:SF27 IMPORTIN-7, 8, 11 IMPORTIN-7 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000777.1|UniProtKB=W5LXK2 W5LXK2 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response#GO:0006955;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;immune system process#GO:0002376 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014502.1|UniProtKB=W5NB53 W5NB53 PTHR43097:SF16 GLUTAMINE-TRNA LIGASE GLUTAMINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418 catalytic complex#GO:1902494;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 LEPOC|Ensembl=ENSLOCG00000008154.1|UniProtKB=W5MNE0 W5MNE0 PTHR16551:SF4 AGOUTI RELATED AGOUTI-RELATED PROTEIN binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;neuropeptide hormone activity#GO:0005184;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;feeding behavior#GO:0007631 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004487.1|UniProtKB=W5MAF8 W5MAF8 PTHR15690:SF0 NUCLEAR RECEPTOR COACTIVATOR 6 NUCLEAR RECEPTOR COACTIVATOR 6 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000007383.1|UniProtKB=W5MKP9 W5MKP9 PTHR24240:SF75 OPSIN VERTEBRATE ANCIENT LONG OPSIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cellular response to radiation#GO:0071478;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;biological regulation#GO:0065007;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;detection of stimulus#GO:0051606 membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016019.1|UniProtKB=W5NGH4 W5NGH4 PTHR11923:SF12 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 PLATELET GLYCOPROTEIN 4 protein-containing complex binding#GO:0044877;low-density lipoprotein particle receptor activity#GO:0005041;cargo receptor activity#GO:0038024;protein-lipid complex binding#GO:0071814;low-density lipoprotein particle binding#GO:0030169;binding#GO:0005488;lipoprotein particle binding#GO:0071813 biological regulation#GO:0065007;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;lipid storage#GO:0019915;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;plasma lipoprotein particle clearance#GO:0034381;import into cell#GO:0098657;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;metabolic process#GO:0008152;catabolic process#GO:0009056;endocytosis#GO:0006897;regulation of biological process#GO:0050789;protein transport#GO:0015031;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;lipid localization#GO:0010876 cell periphery#GO:0071944;membrane raft#GO:0045121;membrane#GO:0016020;caveola#GO:0005901;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell surface#GO:0009986;membrane microdomain#GO:0098857;plasma membrane raft#GO:0044853 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016649.1|UniProtKB=W5NIW0 W5NIW0 PTHR18861:SF1 ELKS/RAB6-INTERACTING/CAST PROTEIN ELKS_RAB6-INTERACTING_CAST FAMILY MEMBER 1 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808 cell junction#GO:0030054;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;presynapse#GO:0098793;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cytoplasm#GO:0005737 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001493.1|UniProtKB=W5M009 W5M009 PTHR11485:SF21 TRANSFERRIN MELANOTRANSFERRIN metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000002981.1|UniProtKB=W5M554 W5M554 PTHR19960:SF12 TEKTIN TEKTIN-4 organelle assembly#GO:0070925;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;cell motility#GO:0048870;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000015066.1|UniProtKB=W5ND36 W5ND36 PTHR24046:SF4 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;cellular developmental process#GO:0048869;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cell differentiation#GO:0030154;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;muscle cell differentiation#GO:0042692;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;muscle cell development#GO:0055001;smoothened signaling pathway#GO:0007224;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000000940.1|UniProtKB=W5LY44 W5LY44 PTHR24103:SF568 E3 UBIQUITIN-PROTEIN LIGASE TRIM B BOX AND SPRY DOMAIN-CONTAINING PROTEIN acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008571.1|UniProtKB=W5MPW7 W5MPW7 PTHR15040:SF2 DERMATOPONTIN-RELATED DERMATOPONTIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cell adhesion#GO:0007155;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;external encapsulating structure organization#GO:0045229 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000074.1|UniProtKB=W5LVD0 W5LVD0 PTHR11804:SF84 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED SACCHAROLYSIN metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007161.1|UniProtKB=W5MJV3 W5MJV3 PTHR45804:SF3 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-A13 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009775.1|UniProtKB=W5MU81 W5MU81 PTHR10285:SF126 URIDINE KINASE NICOTINAMIDE RIBOSIDE KINASE 1 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000014401.1|UniProtKB=W5NAS8 W5NAS8 PTHR10841:SF24 SYNAPSIN SYNAPSIN-1 cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;localization#GO:0051179;synapse organization#GO:0050808;organelle localization#GO:0051640;cell junction organization#GO:0034330;cellular component organization#GO:0016043;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;presynapse#GO:0098793;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synapsin#P05775 LEPOC|Ensembl=ENSLOCG00000015234.1|UniProtKB=W5NDN6 W5NDN6 PTHR23055:SF85 CALCIUM BINDING PROTEINS SI:CH211-245J22.3 metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000001503.1|UniProtKB=W5M008 W5M008 PTHR45783:SF2 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 LEPOC|Ensembl=ENSLOCG00000002360.1|UniProtKB=W5M309 W5M309 PTHR10237:SF15 DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000012685.1|UniProtKB=W5N4Q0 W5N4Q0 PTHR24103:SF588 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM8 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003204.1|UniProtKB=W5M5X9 W5M5X9 PTHR24061:SF581 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR-LIKE transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009967.1|UniProtKB=W5MUX7 W5MUX7 PTHR23235:SF117 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 4 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 CCKR signaling map#P06959>KLF4#P07227 LEPOC|Ensembl=ENSLOCG00000017835.1|UniProtKB=W5NMS9 W5NMS9 PTHR23349:SF70 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TWIST-RELATED PROTEIN 2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000000279.1|UniProtKB=W5LW01 W5LW01 PTHR13139:SF6 RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN ROQUIN-1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA binding#GO:0003723;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;double-stranded RNA binding#GO:0003725;ubiquitin-like protein transferase activity#GO:0019787 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;protein ubiquitination#GO:0016567;positive regulation of macromolecule metabolic process#GO:0010604;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;positive regulation of mRNA catabolic process#GO:0061014;modification-dependent protein catabolic process#GO:0019941;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770 LEPOC|Ensembl=ENSLOCG00000017430.1|UniProtKB=W5NLM6 W5NLM6 PTHR12002:SF112 CLAUDIN CLAUDIN-3 cellular process#GO:0009987;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000018080.1|UniProtKB=W5NNH2 W5NNH2 PTHR11232:SF34 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN FAM43B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;vasculature development#GO:0001944;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004510.1|UniProtKB=W5MAI6 W5MAI6 PTHR10962:SF5 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2C peptide binding#GO:0042277;binding#GO:0005488 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248 cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010644.1|UniProtKB=W5MXC2 W5MXC2 PTHR15750:SF5 VASOHIBIN-1-LIKE ISOFORM X2 TUBULINYL-TYR CARBOXYPEPTIDASE 1 regulation of anatomical structure morphogenesis#GO:0022603;regulation of angiogenesis#GO:0045765;regulation of vasculature development#GO:1901342;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014084.1|UniProtKB=W5N9P6 W5N9P6 PTHR10552:SF11 U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A' nucleic acid binding#GO:0003676;binding#GO:0005488;snRNA binding#GO:0017069;RNA binding#GO:0003723 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000006386.1|UniProtKB=W5MH54 W5MH54 PTHR14319:SF7 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 POST-GPI ATTACHMENT TO PROTEINS FACTOR 6 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001357.1|UniProtKB=W5LZI0 W5LZI0 PTHR22930:SF236 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016981.1|UniProtKB=W5NK34 W5NK34 TUBE1 PTHR11588:SF13 TUBULIN TUBULIN EPSILON CHAIN heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl nucleotide binding#GO:0019001;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 cytoskeletal protein#PC00085;tubulin#PC00228 LEPOC|Ensembl=ENSLOCG00000004038.1|UniProtKB=W5M8Y6 W5M8Y6 PTHR45847:SF6 FATTY ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 1 catalytic activity#GO:0003824;amidase activity#GO:0004040;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 monocarboxylic acid catabolic process#GO:0072329;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;fatty acid catabolic process#GO:0009062;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004423.1|UniProtKB=W5MA75 W5MA75 PTHR46621:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;snRNA transcription#GO:0009301;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;snRNA transcription by RNA polymerase III#GO:0042796;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000004284.1|UniProtKB=W5M9S4 W5M9S4 PTHR31743:SF1 TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN TCPC4AP SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN protein binding#GO:0005515;binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010508.1|UniProtKB=W5MWX4 W5MWX4 PTHR48092:SF5 KNIRPS-RELATED PROTEIN-RELATED GLUCOCORTICOID RECEPTOR signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to steroid hormone#GO:0048545;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;steroid hormone receptor signaling pathway#GO:0043401;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;intracellular receptor signaling pathway#GO:0030522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;cellular response to steroid hormone stimulus#GO:0071383;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 Gonadotropin-releasing hormone receptor pathway#P06664>GR#P06810 LEPOC|Ensembl=ENSLOCG00000016771.1|UniProtKB=W5NJC0 W5NJC0 PTHR24023:SF1047 COLLAGEN ALPHA SCAVENGER RECEPTOR CLASS A MEMBER 3 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000014136.1|UniProtKB=W5N9W0 W5N9W0 PTHR10192:SF33 MOLYBDOPTERIN BIOSYNTHESIS PROTEIN GEPHYRIN transferase activity#GO:0016740;catalytic activity#GO:0003824 localization#GO:0051179;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641;synapse organization#GO:0050808;receptor clustering#GO:0043113;localization within membrane#GO:0051668;cell junction organization#GO:0034330;postsynapse organization#GO:0099173;protein localization to membrane#GO:0072657;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;neuromuscular junction development#GO:0007528;intracellular protein localization#GO:0008104;metabolic process#GO:0008152;membrane organization#GO:0061024;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987 synaptic membrane#GO:0097060;cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;dendritic tree#GO:0097447;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202 LEPOC|Ensembl=ENSLOCG00000017488.1|UniProtKB=W5NLT4 W5NLT4 PTHR24232:SF41 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 4 bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002826.1|UniProtKB=W5M4M2 W5M4M2 PTHR10972:SF46 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 11 sterol binding#GO:0032934;binding#GO:0005488;steroid binding#GO:0005496;lipid binding#GO:0008289 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000008260.1|UniProtKB=W5MNR8 W5MNR8 PTHR13502:SF4 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CDC42 SMALL EFFECTOR PROTEIN 2 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001742.1|UniProtKB=W5M0V3 W5M0V3 PTHR46350:SF1 RAS LIKE FAMILY 10 MEMBER B-RELATED RAS-LIKE PROTEIN FAMILY MEMBER 10B LEPOC|Ensembl=ENSLOCG00000012013.1|UniProtKB=W5N2B9 W5N2B9 PTHR24270:SF2 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED ATRIAL NATRIURETIC PEPTIDE-CONVERTING ENZYME regulation of blood pressure#GO:0008217;circulatory system process#GO:0003013;biological regulation#GO:0065007;system process#GO:0003008;regulation of biological quality#GO:0065008;blood circulation#GO:0008015;multicellular organismal process#GO:0032501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 apolipoprotein#PC00052;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000002026.1|UniProtKB=W5M1T7 W5M1T7 PTHR28559:SF2 DNA REPAIR PROTEIN XRCC4 DNA REPAIR PROTEIN XRCC4 gene expression#GO:0010467;response to stress#GO:0006950;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;multicellular organism development#GO:0007275;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;response to abiotic stimulus#GO:0009628;response to ionizing radiation#GO:0010212;V(D)J recombination#GO:0033151;immune system development#GO:0002520;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;cellular response to stress#GO:0033554;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;multicellular organismal process#GO:0032501;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;somatic cell DNA recombination#GO:0016444;macromolecule biosynthetic process#GO:0009059;response to radiation#GO:0009314;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;DNA repair#GO:0006281;developmental process#GO:0032502;DNA damage response#GO:0006974;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;system development#GO:0048731 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;nucleus#GO:0005634;DNA repair complex#GO:1990391 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000015411.1|UniProtKB=W5NEA4 W5NEA4 PTHR24409:SF413 ZINC FINGER PROTEIN 142 DATILOGRAFO, ISOFORM A-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000003516.1|UniProtKB=W5M709 W5M709 PTHR12066:SF0 TELOMERASE REVERSE TRANSCRIPTASE TELOMERASE REVERSE TRANSCRIPTASE catalytic activity, acting on DNA#GO:0140097;telomerase activity#GO:0003720;DNA polymerase activity#GO:0034061;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA-directed DNA polymerase activity#GO:0003964;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA-templated DNA biosynthetic process#GO:0006278;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;nucleic acid biosynthetic process#GO:0141187;telomere organization#GO:0032200;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014301.1|UniProtKB=W5NAF1 W5NAF1 PTHR24072:SF153 RHO FAMILY GTPASE TRANSFORMING PROTEIN RHOA GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 cell migration#GO:0016477;contractile actin filament bundle assembly#GO:0030038;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;cellular response to stimulus#GO:0051716;actin filament bundle assembly#GO:0051017;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;actin filament bundle organization#GO:0061572;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;actomyosin structure organization#GO:0031032;signaling#GO:0023052;Rho protein signal transduction#GO:0007266;stress fiber assembly#GO:0043149 cleavage furrow#GO:0032154;cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;cell division site#GO:0032153;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cellular anatomical structure#GO:0110165;synapse#GO:0045202 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rho#P00948;Ras Pathway#P04393>Rho#P04578;CCKR signaling map#P06959>RHOA-GDP#P07019;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Axon guidance mediated by semaphorins#P00007>Rho#P00341;CCKR signaling map#P06959>RHOA-GTP#P07188;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Angiogenesis#P00005>GTPase#P00254 LEPOC|Ensembl=ENSLOCG00000010842.1|UniProtKB=W5MY45 W5MY45 PTHR45736:SF6 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 2 zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001053.1|UniProtKB=W5LYM7 W5LYM7 PTHR14907:SF2 FI14130P SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000002139.1|UniProtKB=W5M287 W5M287 PTHR20854:SF29 INOSITOL MONOPHOSPHATASE INOSITOL MONOPHOSPHATASE 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004500.1|UniProtKB=W5MAG8 W5MAG8 PTHR13439:SF2 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 2 cellular component organization#GO:0016043;lipid homeostasis#GO:0055088;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;membrane assembly#GO:0071709;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;homeostatic process#GO:0042592;membrane organization#GO:0061024;biological regulation#GO:0065007;chemical homeostasis#GO:0048878;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;regulation of biological quality#GO:0065008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006128.1|UniProtKB=W5MG98 W5MG98 PTHR14326:SF67 TARGETING PROTEIN FOR XKLP2 TARGETING PROTEIN FOR XKLP2 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;nuclear division#GO:0000280;organelle assembly#GO:0070925;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;sister chromatid segregation#GO:0000819;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000014370.1|UniProtKB=W5NAN4 W5NAN4 PTHR47138:SF1 PERILIPIN-1 PERILIPIN-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152;catabolic process#GO:0009056 intracellular organelle#GO:0043229;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000002261.1|UniProtKB=W5M2N9 W5M2N9 PTHR19384:SF10 NITRIC OXIDE SYNTHASE-RELATED NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1 flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;ribonucleotide binding#GO:0032553;catalytic activity#GO:0003824;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006339.1|UniProtKB=W5MH07 W5MH07 PTHR45858:SF4 FERM DOMAIN CONTAINING PROTEIN FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 LEPOC|Ensembl=ENSLOCG00000018129.1|UniProtKB=W5NNM1 W5NNM1 PTHR24306:SF0 FAMILY NOT NAMED 7-ALPHA-HYDROXYCHOLEST-4-EN-3-ONE 12-ALPHA-HYDROXYLASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 LEPOC|Ensembl=ENSLOCG00000017032.1|UniProtKB=W5NK90 W5NK90 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 14A ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009865.1|UniProtKB=W5MUJ5 W5MUJ5 PTHR15427:SF24 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 7 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003083.1|UniProtKB=W5M5H5 W5M5H5 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007539.1|UniProtKB=W5ML88 W5ML88 PTHR45984:SF2 RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM34 protein binding#GO:0005515;binding#GO:0005488;heat shock protein binding#GO:0031072 protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016637.1|UniProtKB=W5NIU7 W5NIU7 PTHR24115:SF344 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF28P catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515 establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907 microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008305.1|UniProtKB=W5MNY0 W5MNY0 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 LEPOC|Ensembl=ENSLOCG00000002611.1|UniProtKB=W5M3X2 W5M3X2 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016678.1|UniProtKB=W5NIZ7 W5NIZ7 PTHR14343:SF4 VWFA DOMAIN-CONTAINING PROTEIN DUF4537 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011545.1|UniProtKB=W5N0M9 W5N0M9 PTHR12673:SF82 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;filopodium assembly#GO:0046847;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000008102.1|UniProtKB=W5MN83 W5MN83 PTHR10617:SF107 ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL electron transfer activity#GO:0009055;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152;electron transport chain#GO:0022900 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009936.1|UniProtKB=W5MUU1 W5MUU1 PTHR21016:SF1 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 positive regulation of Notch signaling pathway#GO:0045747;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cell death#GO:0008219;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;apoptotic signaling pathway#GO:0097190;regulation of response to stimulus#GO:0048583 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000014883.1|UniProtKB=W5NCG9 W5NCG9 PTHR46221:SF1 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000012874.1|UniProtKB=W5N5E2 W5N5E2 PTHR13723:SF169 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 3 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000009372.1|UniProtKB=W5MSR7 W5MSR7 PTHR15143:SF1 TELETHONIN TELETHONIN ISOFORM X1 structural molecule activity#GO:0005198;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488 detection of stimulus#GO:0051606;tissue development#GO:0009888;blood circulation#GO:0008015;developmental process#GO:0032502;muscle contraction#GO:0006936;detection of mechanical stimulus#GO:0050982;system process#GO:0003008;heart contraction#GO:0060047;response to external stimulus#GO:0009605;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;myofibril assembly#GO:0030239;heart morphogenesis#GO:0003007;actin cytoskeleton organization#GO:0030036;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;organelle assembly#GO:0070925;muscle tissue development#GO:0060537;system development#GO:0048731;supramolecular fiber organization#GO:0097435;tissue morphogenesis#GO:0048729;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;heart development#GO:0007507;animal organ development#GO:0048513;heart process#GO:0003015;muscle system process#GO:0003012;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;skeletal muscle contraction#GO:0003009;circulatory system development#GO:0072359;cell differentiation#GO:0030154;response to mechanical stimulus#GO:0009612;multicellular organismal process#GO:0032501;actin filament organization#GO:0007015;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;striated muscle contraction#GO:0006941;animal organ morphogenesis#GO:0009887;muscle structure development#GO:0061061;actin filament-based process#GO:0030029;neuromuscular process#GO:0050905;cellular component assembly involved in morphogenesis#GO:0010927;anatomical structure development#GO:0048856;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cardiac muscle cell differentiation#GO:0055007;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;muscle organ development#GO:0007517;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;protein-containing complex organization#GO:0043933;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;anatomical structure morphogenesis#GO:0009653;response to abiotic stimulus#GO:0009628;cell development#GO:0048468;response to stimulus#GO:0050896;nervous system process#GO:0050877;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002 I band#GO:0031674;intracellular organelle#GO:0043229;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000001880.1|UniProtKB=W5M1C0 W5M1C0 PTHR21470:SF29 RAB6-INTERACTING PROTEIN GORAB RAB6-INTERACTING GOLGIN cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 LEPOC|Ensembl=ENSLOCG00000002450.1|UniProtKB=W5M3C5 W5M3C5 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013209.1|UniProtKB=W5N6M0 W5N6M0 PTHR14705:SF0 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT BETA CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT BETA developmental process involved in reproduction#GO:0003006;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;spermatid differentiation#GO:0048515;sexual reproduction#GO:0019953;spermatid development#GO:0007286;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;cellular process#GO:0009987;developmental maturation#GO:0021700;male gamete generation#GO:0048232;sperm capacitation#GO:0048240;developmental process#GO:0032502;spermatogenesis#GO:0007283;cell maturation#GO:0048469;cellular developmental process#GO:0048869 transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cation channel complex#GO:0034703;CatSper complex#GO:0036128;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000000780.1|UniProtKB=W5LXL0 W5LXL0 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015901.1|UniProtKB=W5NG21 W5NG21 PTHR21661:SF70 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE hydrolase activity#GO:0016787;ether hydrolase activity#GO:0016803;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012362.1|UniProtKB=W5N3K9 W5N3K9 PTHR23036:SF198 CYTOKINE RECEPTOR CILIARY NEUROTROPHIC FACTOR RECEPTOR signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005426.1|UniProtKB=W5MDT5 W5MDT5 PTHR11751:SF311 ALANINE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE 2 transferase#PC00220;transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000007113.1|UniProtKB=W5MJQ7 W5MJQ7 PTHR22792:SF48 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 4 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000020975.1|UniProtKB=Q8HQN2 Q8HQN2 PTHR46552:SF1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 electron transfer activity#GO:0009055;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;NADH dehydrogenase activity#GO:0003954;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001063.1|UniProtKB=W5LYJ3 W5LYJ3 PTHR22846:SF40 WD40 REPEAT PROTEIN F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN TBL1XR1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription repressor complex#GO:0017053;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Wnt signaling pathway#P00057>Ebi#P01453 LEPOC|Ensembl=ENSLOCG00000008906.1|UniProtKB=W5MR36 W5MR36 PTHR13593:SF147 FAMILY NOT NAMED 1-PHOSPHATIDYLINOSITOL PHOSPHODIESTERASE-RELATED phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000001684.1|UniProtKB=W5M0M9 W5M0M9 PTHR11967:SF2 ALPHA-1-ACID GLYCOPROTEIN ALPHA-1-ACID GLYCOPROTEIN 1 response to stimulus#GO:0050896;acute inflammatory response#GO:0002526;defense response#GO:0006952;immune system process#GO:0002376;response to stress#GO:0006950;immune response#GO:0006955;inflammatory response#GO:0006954 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014703.1|UniProtKB=W5NBU2 W5NBU2 PTHR11125:SF7 SUPPRESSOR OF TY 5 TRANSCRIPTION ELONGATION FACTOR SPT5 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000014338.1|UniProtKB=W5NAK3 W5NAK3 PTHR11533:SF156 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1 metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;proteolysis#GO:0006508;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000017788.1|UniProtKB=W5NMN3 W5NMN3 PTHR15282:SF8 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 2 transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;potassium channel regulator activity#GO:0015459;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;potassium channel activity#GO:0005267;channel regulator activity#GO:0016247;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 regulation of membrane potential#GO:0042391;cellular process#GO:0009987;cardiac muscle cell action potential involved in contraction#GO:0086002;monoatomic cation transmembrane transport#GO:0098655;regulation of multicellular organismal process#GO:0051239;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;action potential#GO:0001508;regulation of biological process#GO:0050789;muscle system process#GO:0003012;heart process#GO:0003015;export from cell#GO:0140352;regulation of system process#GO:0044057;muscle contraction#GO:0006936;transport#GO:0006810;establishment of localization#GO:0051234;cardiac muscle cell contraction#GO:0086003;heart contraction#GO:0060047;system process#GO:0003008;actin filament-based movement#GO:0030048;potassium ion transport#GO:0006813;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;circulatory system process#GO:0003013;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;localization#GO:0051179;monoatomic cation transport#GO:0006812;actin-mediated cell contraction#GO:0070252;metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;regulation of heart contraction#GO:0008016 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000018212.1|UniProtKB=W5NNV4 W5NNV4 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183-LIKE-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008090.1|UniProtKB=W5MN67 W5MN67 PTHR15184:SF88 ATP SYNTHASE ATP SYNTHASE F(1) COMPLEX SUBUNIT BETA, MITOCHONDRIAL monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267 ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144 membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ATP synthase#PC00002 ATP synthesis#P02721>F1 beta#P02794 LEPOC|Ensembl=ENSLOCG00000018340.1|UniProtKB=W5NP82 W5NP82 PTHR22750:SF5 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006189.1|UniProtKB=W5MGH0 W5MGH0 PTHR10671:SF113 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 2 cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;bleb assembly#GO:0032060;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000007346.1|UniProtKB=W5MKJ3 W5MKJ3 PTHR46480:SF1 F20B24.22 VOLTAGE-GATED HYDROGEN CHANNEL 1 passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic cation channel activity#GO:0022843;proton channel activity#GO:0015252;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016025.1|UniProtKB=W5NGH8 W5NGH8 PTHR16434:SF2 EWING'S TUMOR-ASSOCIATED ANTIGEN 1 ETAA1 EWING'S TUMOR-ASSOCIATED ANTIGEN 1 kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 replication fork processing#GO:0031297;regulation of cell cycle process#GO:0010564;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;regulation of cellular response to stress#GO:0080135;DNA-templated DNA replication#GO:0006261;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;replication fork#GO:0005657;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000003295.1|UniProtKB=W5M677 W5M677 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006875.1|UniProtKB=W5MIW1 W5MIW1 PTHR24112:SF32 LEUCINE-RICH REPEAT, ISOFORM F-RELATED CAPPING PROTEIN, ARP2_3 AND MYOSIN-I LINKER PROTEIN 2 regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000018315.1|UniProtKB=W5NP57 W5NP57 PTHR24241:SF135 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007198.1|UniProtKB=W5MK20 W5MK20 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004211.1|UniProtKB=W5M9H4 W5M9H4 PTHR16024:SF8 XK-RELATED PROTEIN XK-RELATED PROTEIN 8 phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;phagocytosis#GO:0006909;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cell death#GO:0008219;programmed cell death#GO:0012501;anatomical structure development#GO:0048856;localization#GO:0051179;endomembrane system organization#GO:0010256;cellular process#GO:0009987;import into cell#GO:0098657;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;apoptotic cell clearance#GO:0043277;membrane invagination#GO:0010324;endocytosis#GO:0006897;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;lipid localization#GO:0010876 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014966.1|UniProtKB=W5NCR6 W5NCR6 PTHR22967:SF101 SERINE/THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;positive regulation of Notch signaling pathway#GO:0045747;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of endocytosis#GO:0030100;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000001448.1|UniProtKB=W5LZT9 W5LZT9 PTHR15836:SF4 PERIPHILIN 1 PERIPHILIN-1 chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule biosynthetic process#GO:0010558;macromolecule localization#GO:0033036;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;intracellular protein localization#GO:0008104;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;localization#GO:0051179 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000002306.1|UniProtKB=W5M2T4 W5M2T4 PTHR24060:SF177 METABOTROPIC GLUTAMATE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;signal transduction#GO:0007165;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016317.1|UniProtKB=W5NHN0 W5NHN0 PTHR23068:SF58 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3 ALPHA A ISOFORM X1-RELATED negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA methyltransferase#PC00013 LEPOC|Ensembl=ENSLOCG00000007565.1|UniProtKB=W5MLC1 W5MLC1 PTHR11814:SF272 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10P-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017334.1|UniProtKB=W5NLD0 W5NLD0 PTHR21338:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L41 LARGE RIBOSOMAL SUBUNIT PROTEIN ML41 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013158.1|UniProtKB=W5N6F2 W5N6F2 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198 cell recognition#GO:0008037;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;binding of sperm to zona pellucida#GO:0007339;anatomical structure development#GO:0048856;germ cell development#GO:0007281;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;cellular process involved in reproduction in multicellular organism#GO:0022412;fertilization#GO:0009566;reproductive process#GO:0022414;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;developmental process#GO:0032502;sperm-egg recognition#GO:0035036;cell-cell recognition#GO:0009988;cellular developmental process#GO:0048869;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;single fertilization#GO:0007338;oogenesis#GO:0048477;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003104.1|UniProtKB=W5M5J4 W5M5J4 PTHR14191:SF4 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515 protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;protein localization to plasma membrane#GO:0072659;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015636.1|UniProtKB=W5NF41 W5NF41 PTHR23055:SF165 CALCIUM BINDING PROTEINS CALSENILIN binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;potassium channel regulator activity#GO:0015459;calcium ion binding#GO:0005509;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;metal ion binding#GO:0046872;sequence-specific DNA binding#GO:0043565;ion binding#GO:0043167;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;small molecule binding#GO:0036094;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transporter regulator activity#GO:0141108;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;channel regulator activity#GO:0016247;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;cation binding#GO:0043169;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;ion channel regulator activity#GO:0099106;sequence-specific double-stranded DNA binding#GO:1990837;molecular function regulator activity#GO:0098772 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of monoatomic ion transmembrane transport#GO:0034765;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of transmembrane transport#GO:0034762;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of metal ion transport#GO:0010959;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of monoatomic ion transport#GO:0043269;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000007889.1|UniProtKB=W5MMH9 W5MMH9 PTHR10117:SF56 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 1 alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480 protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000002080.1|UniProtKB=W5M206 W5M206 PTHR21461:SF52 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008382.1|UniProtKB=W5MP77 W5MP77 PTHR23214:SF1 NEUROFILAMENT TRIPLET H PROTEIN NEUROFILAMENT HEAVY POLYPEPTIDE structural constituent of cytoskeleton#GO:0005200;structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 neuron development#GO:0048666;supramolecular fiber organization#GO:0097435;system development#GO:0048731;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;cell development#GO:0048468;cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cell projection organization#GO:0030030;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;developmental process#GO:0032502;intermediate filament bundle assembly#GO:0045110;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cellular process#GO:0009987;axon development#GO:0061564;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 axon#GO:0030424;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;neuron projection#GO:0043005;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 LEPOC|Ensembl=ENSLOCG00000006766.1|UniProtKB=W5MIG7 W5MIG7 PTHR14233:SF12 DUF914-RELATED QUEUINE_QUEUOSINE TRANSPORTER SLC35F2 LEPOC|Ensembl=ENSLOCG00000015331.1|UniProtKB=W5NE06 W5NE06 PTHR47012:SF3 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 1 LTD DOMAIN-CONTAINING PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000002680.1|UniProtKB=W5M436 W5M436 PTHR47980:SF35 LD44762P RAS-RELATED PROTEIN RAB-12 localization within membrane#GO:0051668;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;secretion by cell#GO:0032940;endocytic recycling#GO:0032456;export from cell#GO:0140352;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;endosomal transport#GO:0016197;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;trans-Golgi network transport vesicle#GO:0030140;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000000432.1|UniProtKB=W5LWG5 W5LWG5 PTHR23184:SF9 TETRATRICOPEPTIDE REPEAT PROTEIN 14 TETRATRICOPEPTIDE REPEAT PROTEIN 14 LEPOC|Ensembl=ENSLOCG00000017502.1|UniProtKB=W5NLU8 W5NLU8 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013738.1|UniProtKB=W5N8I0 W5N8I0 PTHR11949:SF22 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004240.1|UniProtKB=W5M9M9 W5M9M9 PTHR11946:SF118 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000008477.1|UniProtKB=W5MPL0 W5MPL0 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 LEPOC|Ensembl=ENSLOCG00000004312.1|UniProtKB=W5M9U2 W5M9U2 PTHR12002:SF192 CLAUDIN CLAUDIN cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;transport#GO:0006810;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;paracellular transport#GO:0160184 anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000008128.1|UniProtKB=W5MNA8 W5MNA8 PTHR15723:SF0 CARBOHYDRATE SULFOTRANSFERASE 15 CARBOHYDRATE SULFOTRANSFERASE 15 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 hexose biosynthetic process#GO:0019319;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;carbohydrate biosynthetic process#GO:0016051;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000002278.1|UniProtKB=W5M2Q3 W5M2Q3 PTHR14856:SF11 PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN SOLUTE CARRIER FAMILY 66 MEMBER 2 lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;lipid translocation#GO:0034204;cytosolic transport#GO:0016482;organophosphate ester transport#GO:0015748;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000000965.1|UniProtKB=W5LY76 W5LY76 PTHR11827:SF97 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 10, TANDEM DUPLICATE 1 ISOFORM X1-RELATED potassium ion transmembrane transporter activity#GO:0015079;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509 potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic anion transport#GO:0006820;sodium ion transport#GO:0006814;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000003563.1|UniProtKB=W5M759 W5M759 PTHR24363:SF0 SERINE/THREONINE PROTEIN KINASE SERINE_THREONINE KINASE-LIKE DOMAIN-CONTAINING PROTEIN STKLD1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013394.1|UniProtKB=W5N7A8 W5N7A8 PTHR14894:SF0 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000003750.1|UniProtKB=W5M7W2 W5M7W2 PTHR10828:SF78 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 mitotic cell cycle#GO:0000278;G2/M transition of mitotic cell cycle#GO:0000086;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;positive regulation of cell cycle process#GO:0090068;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic cell cycle phase transition#GO:0044772;regulation of reproductive process#GO:2000241;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;regulation of cell cycle G2/M phase transition#GO:1902749;cell cycle G2/M phase transition#GO:0044839;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000002271.1|UniProtKB=W5M2R1 W5M2R1 PTHR46130:SF1 LAMGL DOMAIN-CONTAINING PROTEIN PAPPALYSIN-2 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000005985.1|UniProtKB=W5MFS7 W5MFS7 PTHR16040:SF8 AUSTRALIN, ISOFORM A-RELATED BOREALIN organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic metaphase chromosome alignment#GO:0007080;mitotic cell cycle#GO:0000278;organelle localization#GO:0051640;nuclear division#GO:0000280;organelle fission#GO:0048285;localization#GO:0051179 microtubule cytoskeleton#GO:0015630;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000017804.1|UniProtKB=W5NMP9 W5NMP9 PTHR23430:SF426 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789 intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010534.1|UniProtKB=W5MWZ4 W5MWZ4 PTHR44068:SF1 ZGC:194242 STEROL 4-C-METHYLTRANSFERASE STRM-1 catalytic activity#GO:0003824;transferase activity#GO:0016740;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 cellular process#GO:0009987;primary metabolic process#GO:0044238;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000014945.1|UniProtKB=W5NCP5 W5NCP5 PTHR44186:SF1 FAMILY NOT NAMED BBSOME COMPLEX MEMBER BBS4 LEPOC|Ensembl=ENSLOCG00000002454.1|UniProtKB=W5M3C6 W5M3C6 PTHR22763:SF192 RING ZINC FINGER PROTEIN RING-TYPE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008290.1|UniProtKB=W5MNW2 W5MNW2 PTHR12069:SF0 DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000001912.1|UniProtKB=W5M1F2 W5M1F2 PTHR24329:SF583 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARX transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000016658.1|UniProtKB=W5NIW9 W5NIW9 PTHR11482:SF42 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829 metabolic process#GO:0008152;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987;polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 CCKR signaling map#P06959>ODC1#G06989;CCKR signaling map#P06959>ODC1#P07221;Ornithine degradation#P02758>Ornithine decarboxylase#P03053 LEPOC|Ensembl=ENSLOCG00000004990.1|UniProtKB=W5MCA0 W5MCA0 PTHR12864:SF85 RAN BINDING PROTEIN 9-RELATED GLUCOSE-INDUCED DEGRADATION PROTEIN 8 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;catabolic process#GO:0009056;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of canonical Wnt signaling pathway#GO:0090263;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007767.1|UniProtKB=W5MM24 W5MM24 PTHR45779:SF2 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP11 peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000002331.1|UniProtKB=W5M2X6 W5M2X6 PTHR13507:SF0 PRKR-INTERACTING PROTEIN 1 PRKR-INTERACTING PROTEIN 1 protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;kinase inhibitor activity#GO:0019210;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000017099.1|UniProtKB=W5NKH2 W5NKH2 PTHR13318:SF152 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 4 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000004334.1|UniProtKB=W5M9X8 W5M9X8 PTHR12174:SF39 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2B catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 lysosomal membrane#GO:0005765;cytoplasmic vesicle membrane#GO:0030659;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;cytoplasm#GO:0005737;vacuole#GO:0005773;endoplasmic reticulum#GO:0005783;cytoplasmic side of membrane#GO:0098562;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;Golgi-associated vesicle membrane#GO:0030660;intracellular organelle#GO:0043229;side of membrane#GO:0098552;organelle subcompartment#GO:0031984;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;endoplasmic reticulum membrane#GO:0005789;Golgi-associated vesicle#GO:0005798;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;aspartic protease#PC00053 LEPOC|Ensembl=ENSLOCG00000002326.1|UniProtKB=W5M2Y0 W5M2Y0 PTHR45745:SF2 PHOSPHOMANNOMUTASE 45A GLUCOSE 1,6-BISPHOSPHATE SYNTHASE isomerase activity#GO:0016853;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;intramolecular phosphotransferase activity#GO:0016868;phosphotransferase activity, alcohol group as acceptor#GO:0016773;intramolecular transferase activity#GO:0016866 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;purine nucleoside metabolic process#GO:0042278;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238 isomerase#PC00135;metabolite interconversion enzyme#PC00262;mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000013191.1|UniProtKB=W5N6J3 W5N6J3 PTHR12716:SF8 TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175;transcription factor binding#GO:0008134;binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TFIIE#P00666;General transcription regulation#P00023>TFIIEbeta#P00659;Transcription regulation by bZIP transcription factor#P00055>TFIIEbeta#P01386;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395 LEPOC|Ensembl=ENSLOCG00000006779.1|UniProtKB=W5MII3 W5MII3 PTHR12864:SF19 RAN BINDING PROTEIN 9-RELATED RAN-BINDING PROTEIN 10 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511;organelle organization#GO:0006996;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018168.1|UniProtKB=W5NNR0 W5NNR0 PTHR24225:SF68 CHEMOTACTIC RECEPTOR C3A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR-LIKE-RELATED transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of biological quality#GO:0065008;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002984.1|UniProtKB=W5M556 W5M556 PTHR11885:SF6 RIBOSOMAL PROTEIN S15P/S13E SMALL RIBOSOMAL SUBUNIT PROTEIN US15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;small-subunit processome#GO:0032040;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000014304.1|UniProtKB=W5NAG1 W5NAG1 PTHR13948:SF4 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 10 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000002655.1|UniProtKB=W5M449 W5M449 PTHR23335:SF11 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 1 binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000000050.1|UniProtKB=W5LVA3 W5LVA3 PTHR23238:SF5 RNA BINDING PROTEIN RNA-BINDING PROTEIN FUS RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008257.1|UniProtKB=W5MNR4 W5MNR4 PTHR12560:SF43 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 6 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;ceramide metabolic process#GO:0006672;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007374.1|UniProtKB=W5MKN2 W5MKN2 PTHR15505:SF1 RIIA DOMAIN-CONTAINING PROTEIN 1 BMP AND ACTIVIN MEMBRANE-BOUND INHIBITOR HOMOLOG TGF-beta signaling pathway#P00052>BAMBI#P01287 LEPOC|Ensembl=ENSLOCG00000004131.1|UniProtKB=W5M987 W5M987 PTHR24006:SF902 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 47 catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011463.1|UniProtKB=W5N0C2 W5N0C2 PTHR14206:SF5 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BAR_IMD DOMAIN-CONTAINING ADAPTER PROTEIN 2-LIKE 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;actin filament bundle assembly#GO:0051017;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;actin filament bundle organization#GO:0061572;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005312.1|UniProtKB=W5MDG1 W5MDG1 PTHR24271:SF97 KALLIKREIN-RELATED MAST CELL PROTEASE 2 ISOFORM X1 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000004378.1|UniProtKB=W5MA28 W5MA28 PTHR46485:SF7 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 1 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;positive regulation of actin filament bundle assembly#GO:0032233;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;positive regulation of organelle organization#GO:0010638;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Cytoskeletal regulation by Rho GTPase#P00016>LIMK#P00524 LEPOC|Ensembl=ENSLOCG00000011519.1|UniProtKB=W5N0J8 W5N0J8 PTHR24356:SF221 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 38 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;establishment or maintenance of cell polarity#GO:0007163;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002551.1|UniProtKB=W5M3N8 W5M3N8 PTHR24115:SF454 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2C cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018 cytoskeleton#GO:0005856;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000008414.1|UniProtKB=W5MPB7 W5MPB7 PTHR11214:SF361 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000014668.1|UniProtKB=W5NBP5 W5NBP5 PTHR10177:SF257 CYCLINS CYCLIN-P enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000009406.1|UniProtKB=W5MSY3 W5MSY3 PTHR23120:SF0 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 1 ISOFORM X1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000127.1|UniProtKB=W5LVI2 W5LVI2 PTHR19143:SF425 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004247.1|UniProtKB=W5M9M4 W5M9M4 PTHR13713:SF37 SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-BETA-1,4-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000619.1|UniProtKB=W5LX22 W5LX22 PTHR11929:SF198 ALPHA- 1,3 -FUCOSYLTRANSFERASE GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 4 glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920;transferase activity#GO:0016740;catalytic activity#GO:0003824;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000015540.1|UniProtKB=W5NER9 W5NER9 PTHR11724:SF1 LEPTIN LEPTIN protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cytokine-mediated signaling pathway#GO:0019221;energy reserve metabolic process#GO:0006112;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;lipid metabolic process#GO:0006629;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;response to peptide hormone#GO:0043434;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to hormone#GO:0009725;response to cytokine#GO:0034097;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000002871.1|UniProtKB=W5M4R3 W5M4R3 PTHR33618:SF1 39S RIBOSOMAL PROTEIN L53, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML53 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000014808.1|UniProtKB=W5NC74 W5NC74 PTHR13800:SF13 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 1 metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085 cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000015964.1|UniProtKB=W5NG99 W5NG99 PTHR13006:SF6 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 ZINC FINGER PROTEIN 395 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000014519.1|UniProtKB=W5NB64 W5NB64 PTHR12612:SF9 NUCLEAR TRANSPORT FACTOR 2 NTF2-RELATED EXPORT PROTEIN 2-RELATED macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000004238.1|UniProtKB=W5M9M6 W5M9M6 PTHR24083:SF174 NUCLEAR HORMONE RECEPTOR HEPATIC NUCLEAR FACTOR 4BETA signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of RNA metabolic process#GO:0051254;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000007225.1|UniProtKB=W5MK45 W5MK45 PTHR46850:SF1 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 ATP-DEPENDENT CHROMATIN REMODELER CHD9 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004231.1|UniProtKB=W5M9K5 W5M9K5 PTHR12172:SF5 CELL CYCLE CHECKPOINT PROTEIN RAD17 CELL CYCLE CHECKPOINT PROTEIN RAD17 chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle G2/M phase transition#GO:1902750;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;cellular response to stress#GO:0033554;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;mitotic DNA replication checkpoint signaling#GO:0033314;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726 protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;site of DNA damage#GO:0090734;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011345.1|UniProtKB=W5MZZ3 W5MZZ3 PTHR10649:SF20 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR 1A double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000008646.1|UniProtKB=W5MQ49 W5MQ49 PTHR14241:SF1 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 LEPOC|Ensembl=ENSLOCG00000012027.1|UniProtKB=W5N2D2 W5N2D2 PTHR10984:SF36 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000014309.1|UniProtKB=W5NAG0 W5NAG0 PTHR11010:SF123 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED THYMUS-SPECIFIC SERINE PROTEASE endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000013657.1|UniProtKB=W5N887 W5N887 PTHR13140:SF341 MYOSIN UNCONVENTIONAL MYOSIN-IE isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146 transport#GO:0006810;actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000004754.1|UniProtKB=W5MBE4 W5MBE4 PTHR11863:SF247 STEROL DESATURASE LATHOSTEROL OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000004469.1|UniProtKB=W5MAD3 W5MAD3 PTHR21402:SF5 GAMETOCYTE SPECIFIC FACTOR 1-RELATED GAMETOCYTE-SPECIFIC FACTOR 1 LEPOC|Ensembl=ENSLOCG00000017974.1|UniProtKB=W5NN66 W5NN66 PTHR22639:SF13 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3-LIKE viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000011656.1|UniProtKB=W5N112 W5N112 PTHR12307:SF7 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3G polysaccharide binding#GO:0030247;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;carbohydrate binding#GO:0030246;protein binding#GO:0005515;protein phosphatase binding#GO:0019903 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000015659.1|UniProtKB=W5NF70 W5NF70 PTHR13288:SF9 SPLICING FACTOR 45 SPF45 SPLICING FACTOR 45 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000010054.1|UniProtKB=W5MV87 W5MV87 PTHR23113:SF186 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1C guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000007843.1|UniProtKB=W5MMA8 W5MMA8 PTHR11442:SF7 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT BETA-RELATED binding#GO:0005488;molecular carrier activity#GO:0140104;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;transport#GO:0006810;developmental process#GO:0032502;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;localization#GO:0051179;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 globin#PC00107;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000008303.1|UniProtKB=W5MNX7 W5MNX7 PTHR12289:SF34 METAXIN RELATED METAXIN-1 cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036 mitochondrial outer membrane translocase complex#GO:0005742;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015448.1|UniProtKB=W5NEF5 W5NEF5 PTHR11461:SF13 SERINE PROTEASE INHIBITOR, SERPIN ANGIOTENSINOGEN enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867 cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;regulation of apoptotic process#GO:0042981;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to nitrogen compound#GO:1901698;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>AngII#P05935 LEPOC|Ensembl=ENSLOCG00000010980.1|UniProtKB=W5MYK9 W5MYK9 PTHR19325:SF569 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT COMPONENT 4 BINDING PROTEIN, SECRETORY-RELATED defense/immunity protein#PC00090;complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000012973.1|UniProtKB=W5N5R9 W5N5R9 PTHR46535:SF1 NEDD4-BINDING PROTEIN 2 NEDD4-BINDING PROTEIN 2 nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 LEPOC|Ensembl=ENSLOCG00000017595.1|UniProtKB=W5NM41 W5NM41 PTHR16121:SF2 CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000017868.1|UniProtKB=W5NMW2 W5NMW2 PTHR26451:SF869 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 530-RELATED binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003866.1|UniProtKB=W5M8A3 W5M8A3 PTHR14132:SF14 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 5 transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of cellular process#GO:0050794;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000012577.1|UniProtKB=W5N4C4 W5N4C4 PTHR16830:SF24 SH2 CONTAINING ADAPTOR PRAM-1 RELATED FYN-BINDING PROTEIN 1 immune system process#GO:0002376;cellular localization#GO:0051641;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;protein localization to membrane#GO:0072657;signaling#GO:0023052;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;protein localization to cell periphery#GO:1990778;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;antigen receptor-mediated signaling pathway#GO:0050851;localization within membrane#GO:0051668;regulation of immune response#GO:0050776;cell communication#GO:0007154;localization#GO:0051179;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000608.1|UniProtKB=W5LX13 W5LX13 PTHR43684:SF2 FAMILY NOT NAMED CHROMODOMAIN Y-LIKE PROTEIN 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;nucleus#GO:0005634;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000004030.1|UniProtKB=W5M8V6 W5M8V6 PTHR46189:SF2 LD41958P WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 1 positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;positive regulation of response to external stimulus#GO:0032103;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;positive regulation of immune system process#GO:0002684;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008801.1|UniProtKB=W5MQQ8 W5MQQ8 PTHR46099:SF2 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ENDOTHELIN-1 RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 system process#GO:0003008;regulation of anatomical structure size#GO:0090066;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;cellular process#GO:0009987;developmental pigmentation#GO:0048066;signal transduction#GO:0007165;cell communication#GO:0007154;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;pigmentation#GO:0043473;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 Endothelin signaling pathway#P00019>ET-RA/B#P00580 LEPOC|Ensembl=ENSLOCG00000006520.1|UniProtKB=W5MHM1 W5MHM1 PTHR21152:SF40 AMINOTRANSFERASE CLASS V ALANINE--GLYOXYLATE AMINOTRANSFERASE transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;glyoxylate metabolic process#GO:0046487;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;monocarboxylic acid catabolic process#GO:0072329;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;aldehyde catabolic process#GO:0046185;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579 transaminase#PC00216;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000001863.1|UniProtKB=W5M199 W5M199 PTHR24253:SF70 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 5 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000008622.1|UniProtKB=W5MQ26 W5MQ26 PTHR24012:SF702 RNA BINDING PROTEIN RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014480.1|UniProtKB=W5NB13 W5NB13 PTHR15275:SF0 CG1 PROTEIN/F18 MASTERMIND-LIKE DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 LEPOC|Ensembl=ENSLOCG00000002988.1|UniProtKB=W5M561 W5M561 PTHR10015:SF278 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 5 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000010817.1|UniProtKB=W5MY10 W5MY10 PTHR12549:SF7 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE 3A DNA binding#GO:0003677;histone modifying activity#GO:0140993;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;chromatin DNA binding#GO:0031490;histone demethylase activity#GO:0032452 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000014688.1|UniProtKB=W5NBS6 W5NBS6 PTHR12659:SF3 RHO-TYPE GTPASE ACTIVATING PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 8 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cytoskeleton organization#GO:0007010;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of Rho protein signal transduction#GO:0035023;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;actin filament-based process#GO:0030029;regulation of signaling#GO:0023051 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000007084.1|UniProtKB=W5MJL8 W5MJL8 PTHR45701:SF6 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 3 protein binding#GO:0005515;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;binding#GO:0005488 localization#GO:0051179;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;transport#GO:0006810;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 membrane traffic protein#PC00150 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423 LEPOC|Ensembl=ENSLOCG00000009582.1|UniProtKB=W5MTJ6 W5MTJ6 SPMIP5 PTHR47301:SF1 HYPOTHETICAL PROTEIN LOC681006 SPERM-ASSOCIATED MICROTUBULE INNER PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000000976.1|UniProtKB=W5LY91 W5LY91 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000018266.1|UniProtKB=W5NP08 W5NP08 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010361.1|UniProtKB=W5MWD6 W5MWD6 PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN SENTAN calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000007115.1|UniProtKB=W5MJQ3 W5MJQ3 PTHR21562:SF10 NOTUM-RELATED CARBOXYLESTERASE NOTUM2 LEPOC|Ensembl=ENSLOCG00000015973.1|UniProtKB=W5NGA6 W5NGA6 PTHR11309:SF35 FRIZZLED PROTEIN SMOOTHENED binding#GO:0005488;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 system development#GO:0048731;smoothened signaling pathway#GO:0007224;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;central nervous system development#GO:0007417;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175 membrane-bounded organelle#GO:0043227;dendrite#GO:0030425;dendritic tree#GO:0097447;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Hedgehog signaling pathway#P00025>Smoothened#P00685 LEPOC|Ensembl=ENSLOCG00000000884.1|UniProtKB=W5LXX4 W5LXX4 PTHR46317:SF3 HYDROLASE OF PHP SUPERFAMILY-RELATED PROTEIN DEOXYRIBONUCLEASE TATDN3-RELATED hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000962.1|UniProtKB=W5LY65 W5LY65 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017481.1|UniProtKB=W5NLS7 W5NLS7 PTHR11984:SF49 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000017105.1|UniProtKB=W5NKH9 W5NKH9 PTHR28547:SF1 PROTEIN MMS22-LIKE PROTEIN MMS22-LIKE DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000000058.1|UniProtKB=W5LVB1 W5LVB1 PTHR47306:SF2 SI:CH211-178J18.4-RELATED SET DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002710.1|UniProtKB=W5M487 W5M487 PTHR13847:SF294 SARCOSINE DEHYDROGENASE-RELATED FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000000213.1|UniProtKB=W5LVT5 W5LVT5 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007387.1|UniProtKB=W5MKQ5 W5MKQ5 PTHR47222:SF2 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 687 LEPOC|Ensembl=ENSLOCG00000007323.1|UniProtKB=W5MKH0 W5MKH0 PTHR22829:SF5 DEP DOMAIN PROTEIN LYSOSOMAL CHOLESTEROL SIGNALING PROTEIN negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of BMP signaling pathway#GO:0030514;regulation of BMP signaling pathway#GO:0030510;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000000899.1|UniProtKB=W5LXZ5 W5LXZ5 PTHR12086:SF9 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton-dependent cytokinesis#GO:0061640;cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;cytokinesis#GO:0000910;cilium or flagellum-dependent cell motility#GO:0001539;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell motility#GO:0048870;mitotic cytokinesis#GO:0000281;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell division#GO:0051301;cell cycle process#GO:0022402 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;spindle#GO:0005819;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;intracellular organelle#GO:0043229;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;mitotic spindle#GO:0072686;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000017668.1|UniProtKB=W5NMB4 W5NMB4 PTHR22639:SF13 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3-LIKE viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000003557.1|UniProtKB=W5M747 W5M747 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception of light stimulus#GO:0050953 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008111.1|UniProtKB=W5MN93 W5MN93 PTHR24230:SF61 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012252.1|UniProtKB=W5N369 W5N369 PTHR48482:SF5 INTERLEUKIN-19-RELATED INTERLEUKIN-10 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 negative regulation of biological process#GO:0048519;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;negative regulation of response to external stimulus#GO:0032102;cell surface receptor signaling pathway#GO:0007166;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;negative regulation of defense response#GO:0031348;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;cytokine-mediated signaling pathway#GO:0019221;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Interleukin signaling pathway#P00036>Interleukin#P00970 LEPOC|Ensembl=ENSLOCG00000009215.1|UniProtKB=W5MS81 W5MS81 PTHR12027:SF75 WNT RELATED PROTEIN WNT-9A receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell fate commitment#GO:0045165;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000002171.1|UniProtKB=W5M2D0 W5M2D0 PTHR10677:SF62 UBIQUILIN UBIQUILIN 1-RELATED protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012490.1|UniProtKB=W5N421 W5N421 PTHR22014:SF2 RNA-BINDING PROTEIN 33 RNA-BINDING PROTEIN 33 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 LEPOC|Ensembl=ENSLOCG00000008247.1|UniProtKB=W5MNP8 W5MNP8 TDO2 PTHR10138:SF0 TRYPTOPHAN 2,3-DIOXYGENASE TRYPTOPHAN 2,3-DIOXYGENASE heme binding#GO:0020037;catalytic activity#GO:0003824;binding#GO:0005488;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000006342.1|UniProtKB=W5MH56 W5MH56 PTHR11139:SF134 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE MTOR protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;regulation of macroautophagy#GO:0016241;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of macroautophagy#GO:0016242;regulation of metabolic process#GO:0019222;TOR signaling#GO:0031929;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;negative regulation of catabolic process#GO:0009895;TORC1 signaling#GO:0038202;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;TORC2 signaling#GO:0038203;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;TOR complex#GO:0038201;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway by glucose deprivation#P04397>mTOR#P04638;PDGF signaling pathway#P00047>mTOR#P01144;Interleukin signaling pathway#P00036>mTOR#P00966;Hypoxia response via HIF activation#P00030>TOR#P00817 LEPOC|Ensembl=ENSLOCG00000011360.1|UniProtKB=W5N019 W5N019 PTHR22957:SF195 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 4 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000012329.1|UniProtKB=W5N3G4 W5N3G4 PTHR24072:SF144 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOV hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;actin filament organization#GO:0007015;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;signaling#GO:0023052;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;localization#GO:0051179;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000000406.1|UniProtKB=W5LWD5 W5LWD5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001086.1|UniProtKB=W5LYL6 W5LYL6 PTHR31543:SF3 DYNEIN REGULATORY COMPLEX SUBUNIT 4 DYNEIN REGULATORY COMPLEX SUBUNIT 4 positive regulation of signaling#GO:0023056;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;regulation of signaling#GO:0023051;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;positive regulation of biological process#GO:0048518;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;cell motility#GO:0048870;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;microtubule-based movement#GO:0007018;regulation of cell communication#GO:0010646;reproductive process#GO:0022414;positive regulation of signal transduction#GO:0009967;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;plasma membrane bounded cell projection organization#GO:0120036;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;Golgi apparatus#GO:0005794;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;sperm flagellum#GO:0036126;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000014162.1|UniProtKB=W5N9Y8 W5N9Y8 PTHR13589:SF4 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 3 transcription coactivator activity#GO:0003713;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;binding#GO:0005488;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of signal transduction#GO:0009966;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000004907.1|UniProtKB=W5MBZ8 W5MBZ8 PTHR12544:SF33 GLUTAMINASE GLUTAMINASE LIVER ISOFORM, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017500.1|UniProtKB=W5NLU6 W5NLU6 PTHR24237:SF7 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;sterol binding#GO:0032934;lipid binding#GO:0008289;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;steroid binding#GO:0005496;G protein-coupled receptor activity#GO:0004930 taxis#GO:0042330;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;regulation of multicellular organismal process#GO:0051239;regulation of mononuclear cell proliferation#GO:0032944;regulation of B cell activation#GO:0050864;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;lymphocyte activation involved in immune response#GO:0002285;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;B cell activation#GO:0042113;regulation of B cell proliferation#GO:0030888;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;positive regulation of leukocyte activation#GO:0002696;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;cell activation involved in immune response#GO:0002263;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;B cell activation involved in immune response#GO:0002312;cell migration#GO:0016477;multicellular organismal process#GO:0032501;regulation of lymphocyte proliferation#GO:0050670;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;response to external stimulus#GO:0009605;leukocyte chemotaxis#GO:0030595;leukocyte migration#GO:0050900;positive regulation of leukocyte proliferation#GO:0070665;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of B cell proliferation#GO:0030890;locomotion#GO:0040011;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;cell chemotaxis#GO:0060326;chemotaxis#GO:0006935;positive regulation of lymphocyte proliferation#GO:0050671;cell activation#GO:0001775 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005223.1|UniProtKB=W5MD40 W5MD40 PTHR11959:SF12 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013084.1|UniProtKB=W5N663 W5N663 PTHR12591:SF2 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE 3 sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;glucose metabolic process#GO:0006006;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;small molecule metabolic process#GO:0044281;carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003452.1|UniProtKB=W5M6U1 W5M6U1 PTHR24253:SF200 TRANSMEMBRANE PROTEASE SERINE HEPSIN peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000016313.1|UniProtKB=W5NHM6 W5NHM6 PTHR23050:SF531 CALCIUM BINDING PROTEIN CALMODULIN-1 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;cation binding#GO:0043169;molecular function activator activity#GO:0140677;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;kinase activator activity#GO:0019209;ion binding#GO:0043167 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of biological process#GO:0050789;detection of chemical stimulus#GO:0009593;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;response to calcium ion#GO:0051592;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;detection of stimulus#GO:0051606;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of calcium ion transport#GO:0051924;regulation of monoatomic ion transport#GO:0043269;positive regulation of response to stimulus#GO:0048584;response to metal ion#GO:0010038;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of monoatomic cation transmembrane transport#GO:1904062;calcium-mediated signaling#GO:0019722;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of transmembrane transport#GO:0034762;calcineurin-mediated signaling#GO:0097720;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;myelin sheath#GO:0043209;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634 calmodulin-related#PC00061;calcium-binding protein#PC00060 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305;CCKR signaling map#P06959>CaM#P07193 LEPOC|Ensembl=ENSLOCG00000016997.1|UniProtKB=W5NK52 W5NK52 PTHR12334:SF6 BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of biological quality#GO:0065008;protein stabilization#GO:0050821;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000006490.1|UniProtKB=W5MHI2 W5MHI2 PTHR24068:SF553 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000013500.1|UniProtKB=W5N7N7 W5N7N7 PTHR13866:SF26 SPARC OSTEONECTIN SPARC small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 embryo development#GO:0009790;tube development#GO:0035295;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;inner ear development#GO:0048839;inner ear morphogenesis#GO:0042472;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of cellular process#GO:0050794;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;regulation of cellular component organization#GO:0051128;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;ear development#GO:0043583;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;embryonic organ development#GO:0048568;regulation of synapse organization#GO:0050807;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000016529.1|UniProtKB=W5NIF5 W5NIF5 PTHR23137:SF24 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2A LEPOC|Ensembl=ENSLOCG00000013819.1|UniProtKB=W5N8T0 W5N8T0 PTHR11544:SF143 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000009902.1|UniProtKB=W5MUP6 W5MUP6 PTHR12548:SF4 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000004274.1|UniProtKB=W5M9P9 W5M9P9 PTHR23288:SF3 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL MARVEL DOMAIN-CONTAINING PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;snRNA metabolic process#GO:0016073;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;cell-cell junction organization#GO:0045216;biosynthetic process#GO:0009058;positive regulation of RNA biosynthetic process#GO:1902680;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;regulation of DNA-templated transcription elongation#GO:0032784;snRNA transcription#GO:0009301;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;gene expression#GO:0010467;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;nucleus#GO:0005634;tight junction#GO:0070160;cell junction#GO:0030054;nuclear protein-containing complex#GO:0140513;apical junction complex#GO:0043296;apical part of cell#GO:0045177;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;vesicle#GO:0031982;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011632.1|UniProtKB=W5N0Y7 W5N0Y7 PTHR45624:SF7 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 48 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002189.1|UniProtKB=W5M2F5 W5M2F5 PTHR15564:SF2 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cell differentiation#GO:0030154;central nervous system development#GO:0007417;generation of neurons#GO:0048699;response to oxygen-containing compound#GO:1901700;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;nervous system development#GO:0007399;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;negative regulation of cell cycle#GO:0045786;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;cellular developmental process#GO:0048869 neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425 LEPOC|Ensembl=ENSLOCG00000016949.1|UniProtKB=W5NJZ3 W5NJZ3 PTHR15489:SF2 CASPASE 8 ASSOCIATED PROTEIN 2 CASP8-ASSOCIATED PROTEIN 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 cell communication#GO:0007154;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;apoptotic signaling pathway#GO:0097190;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007 intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009723.1|UniProtKB=W5MU15 W5MU15 PTHR16517:SF12 TUBBY-RELATED TUBBY-RELATED PROTEIN 1 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365;macromolecule localization#GO:0033036 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008665.1|UniProtKB=W5MQ93 W5MQ93 PTHR14206:SF4 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BAR_IMD DOMAIN-CONTAINING ADAPTER PROTEIN 2-LIKE 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;actin filament bundle assembly#GO:0051017;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;actin filament bundle organization#GO:0061572;regulation of organelle organization#GO:0033043;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007579.1|UniProtKB=W5MLD7 W5MLD7 PTHR24247:SF236 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 6 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594 synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000009474.1|UniProtKB=W5MT99 W5MT99 PTHR13817:SF69 TITIN ROUNDABOUT GUIDANCE RECEPTOR 2 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016476.1|UniProtKB=W5NI94 W5NI94 PTHR45851:SF2 MYC PROTO-ONCOGENE N-MYC PROTO-ONCOGENE PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000005178.1|UniProtKB=W5MCY1 W5MCY1 PTHR21646:SF76 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 32 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;regulation of protein stability#GO:0031647;positive regulation of cellular process#GO:0048522;positive regulation of TORC1 signaling#GO:1904263;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of TORC1 signaling#GO:1903432;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological quality#GO:0065008;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000012204.1|UniProtKB=W5N308 W5N308 PTHR22834:SF9 NUCLEAR FUSION PROTEIN FUS2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 37 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013156.1|UniProtKB=W5N6E9 W5N6E9 PTHR16277:SF16 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 SERTA DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000004830.1|UniProtKB=W5MBQ3 W5MBQ3 PTHR10822:SF34 GLYPICAN GLYPICAN 6 regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;biological regulation#GO:0065007;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell migration#GO:0016477;cellular process#GO:0009987;regulation of protein localization to membrane#GO:1905475;regulation of biological process#GO:0050789 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell surface#GO:0009986 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010229.1|UniProtKB=W5MVW7 W5MVW7 PTHR46815:SF1 PROTEIN KISH-B PROTEIN KISH-B LEPOC|Ensembl=ENSLOCG00000005304.1|UniProtKB=W5MDD6 W5MDD6 PTHR23055:SF168 CALCIUM BINDING PROTEINS GUANYLATE CYCLASE ACTIVATING PROTEIN 7 molecular function regulator activity#GO:0098772;cyclase regulator activity#GO:0010851;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;cation binding#GO:0043169;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of light stimulus#GO:0050953;system process#GO:0003008;multicellular organismal process#GO:0032501;visual perception#GO:0007601 photoreceptor inner segment#GO:0001917;cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000001354.1|UniProtKB=W5LZH9 W5LZH9 PTHR11588:SF492 TUBULIN TUBULIN, ALPHA 4 LIKE ISOFORM X1 anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226 tubulin#PC00228;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000008786.1|UniProtKB=W5MQN9 W5MQN9 PTHR16140:SF0 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000016100.1|UniProtKB=W5NGT0 W5NGT0 PTHR11647:SF56 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;dihydropyrimidinase activity#GO:0004157 metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 LEPOC|Ensembl=ENSLOCG00000002980.1|UniProtKB=W5M545 W5M545 PTHR15740:SF1 NEUROPROTECTIVE PEPTIDE-CONTAINING PROTEIN ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000004213.1|UniProtKB=W5M9H6 W5M9H6 PTHR28616:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 125 COILED-COIL DOMAIN-CONTAINING PROTEIN 125 negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of locomotion#GO:0040012;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000016132.1|UniProtKB=W5NGW8 W5NGW8 PTHR11224:SF37 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010319.1|UniProtKB=W5MW94 W5MW94 PTHR15117:SF2 ATAXIN 7 RELATED ATAXIN-7 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of gene expression#GO:0010468;microtubule-based process#GO:0007017;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;cytoskeleton organization#GO:0007010;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;microtubule cytoskeleton organization#GO:0000226;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000001852.1|UniProtKB=W5M1D0 W5M1D0 PTHR12185:SF16 SID1 TRANSMEMBRANE FAMILY MEMEBER SID1 TRANSMEMBRANE FAMILY MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488;nucleobase-containing compound transmembrane transporter activity#GO:0015932;RNA binding#GO:0003723 establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;nucleic acid transport#GO:0050657;localization#GO:0051179;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;plasma membrane#GO:0005886;membrane#GO:0016020;lysosome#GO:0005764;cell periphery#GO:0071944;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003674.1|UniProtKB=W5M7K8 W5M7K8 PTHR10434:SF11 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000018053.1|UniProtKB=W5NNE5 W5NNE5 PTHR12002:SF220 CLAUDIN CLAUDIN paracellular tight junction channel activity#GO:0160187;transporter activity#GO:0005215 cell-cell junction organization#GO:0045216;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;paracellular transport#GO:0160184;establishment of localization#GO:0051234;cellular process#GO:0009987;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330 apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000015430.1|UniProtKB=W5NED3 W5NED3 PTHR11905:SF32 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 28 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012158.1|UniProtKB=W5N2U5 W5N2U5 PTHR31433:SF0 PX DOMAIN-CONTAINING PROTEIN 1 PX DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000015032.1|UniProtKB=W5ND05 W5ND05 PTHR24351:SF98 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-6 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;TORC1 signaling#GO:0038202;cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331;TOR signaling#GO:0031929;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;DNA damage response#GO:0006974 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Ras Pathway#P04393>p90RSK#P04541;Interleukin signaling pathway#P00036>p90RSK#P00964 LEPOC|Ensembl=ENSLOCG00000012038.1|UniProtKB=W5N2F4 W5N2F4 PTHR15146:SF1 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137C regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of TORC1 signaling#GO:1904263;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852 LEPOC|Ensembl=ENSLOCG00000006745.1|UniProtKB=W5MIE2 W5MIE2 PTHR16306:SF0 TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1 TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006590.1|UniProtKB=W5MHV2 W5MHV2 PTHR47238:SF2 MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE HEMIPTEROUS non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>MKK4,7#P00637;EGF receptor signaling pathway#P00018>MKK4,7#P00555 LEPOC|Ensembl=ENSLOCG00000002989.1|UniProtKB=W5M562 W5M562 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013377.1|UniProtKB=W5N782 W5N782 PTHR13020:SF9 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;positive regulation of metabolic process#GO:0009893;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of RNA metabolic process#GO:0051252 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016978.1|UniProtKB=W5NK27 W5NK27 PTHR14353:SF9 MYRISTOYLATED ALANINE-RICH C-KINASE SUBSTRATE MARCKS MYRISTOYLATED ALANINE-RICH C-KINASE SUBSTRATE protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 central nervous system development#GO:0007417;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;developmental process#GO:0032502 cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin filament bundle#GO:0032432 LEPOC|Ensembl=ENSLOCG00000006499.1|UniProtKB=W5MHJ9 W5MHJ9 PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000002151.1|UniProtKB=W5M297 W5M297 PTHR12280:SF25 PANTOTHENATE KINASE PANTOTHENATE KINASE 2, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 LEPOC|Ensembl=ENSLOCG00000016681.1|UniProtKB=W5NIZ9 W5NIZ9 PTHR45890:SF26 AARF DOMAIN CONTAINING KINASE 2 (PREDICTED) NADH:UBIQUINONE OXIDOREDUCTASE SUBUNIT B2 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011590.1|UniProtKB=W5N0T9 W5N0T9 PTHR24037:SF7 HEART DEVELOPMENT PROTEIN WITH EGF-LIKE DOMAINS 1 MUCIN 13B, CELL SURFACE-ASSOCIATED LEPOC|Ensembl=ENSLOCG00000015627.1|UniProtKB=W5NF28 W5NF28 PTHR10778:SF4 SOLUTE CARRIER FAMILY 35 MEMBER B NUCLEOTIDE SUGAR TRANSPORTER SLC35B4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;nucleotide-sugar transmembrane transport#GO:0015780;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000018097.1|UniProtKB=W5NNI9 W5NNI9 PTHR25462:SF310 BONUS, ISOFORM C-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 59 ISOFORM X1 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000018201.1|UniProtKB=W5NNU3 W5NNU3 PTHR14315:SF20 SPOT14 FAMILY MEMBER MID1-INTERACTING PROTEIN 1-B-LIKE regulation of lipid biosynthetic process#GO:0046890;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000006811.1|UniProtKB=W5MIM5 W5MIM5 PTHR15711:SF17 RAP GTPASE-ACTIVATING PROTEIN RAP1 GTPASE-ACTIVATING PROTEIN 2 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 axon#GO:0030424;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000015477.1|UniProtKB=W5NEJ2 W5NEJ2 PTHR11787:SF3 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR ALPHA molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005997.1|UniProtKB=W5MFU6 W5MFU6 PTHR11785:SF398 AMINO ACID TRANSPORTER Y+L AMINO ACID TRANSPORTER 2 L-amino acid transmembrane transporter activity#GO:0015179;basic amino acid transmembrane transporter activity#GO:0015174;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 cellular process#GO:0009987;transport#GO:0006810;amino acid transport#GO:0006865;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004643.1|UniProtKB=W5MB13 W5MB13 PTHR12706:SF35 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH HOMOLOG 2 histone binding#GO:0042393;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;protein binding#GO:0005515;DNA binding#GO:0003677 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016064.1|UniProtKB=W5NGN2 W5NGN2 PTHR24103:SF611 E3 UBIQUITIN-PROTEIN LIGASE TRIM BBOX AND DUF4200 DOMAIN-CONTAINING PROTEIN-RELATED ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010385.1|UniProtKB=W5MWH4 W5MWH4 PTHR43816:SF2 NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine-containing compound metabolic process#GO:0072524;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015454.1|UniProtKB=W5NEG6 W5NEG6 PTHR11675:SF49 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000014573.1|UniProtKB=W5NBC5 W5NBC5 PTHR12419:SF122 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 5 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;negative regulation of cell communication#GO:0010648;positive regulation of TORC1 signaling#GO:1904263;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;positive regulation of response to stimulus#GO:0048584;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000009584.1|UniProtKB=W5MTJ9 W5MTJ9 PTHR28567:SF4 PROTEIN FAM53A-LIKE ISOFORM X1 PROTEIN FAM53C establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;cellular localization#GO:0051641 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000007388.1|UniProtKB=W5MKQ6 W5MKQ6 PTHR46026:SF4 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F PH DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;lamellipodium assembly#GO:0030032;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840 cell leading edge#GO:0031252;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000010720.1|UniProtKB=W5MXM7 W5MXM7 PTHR43377:SF1 BILIVERDIN REDUCTASE A BILIVERDIN REDUCTASE A dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000003350.1|UniProtKB=W5M6F1 W5M6F1 PTHR10582:SF5 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 2 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000000557.1|UniProtKB=W5LWV8 W5LWV8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006680.1|UniProtKB=W5MI52 W5MI52 PTHR20913:SF10 TBC1 DOMAIN FAMILY MEMBER 20/GTPASE TBC1 DOMAIN FAMILY MEMBER 20 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;establishment of localization in cell#GO:0051649;Golgi organization#GO:0007030;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000013839.1|UniProtKB=W5N8V7 W5N8V7 PTHR28593:SF6 METEORIN-LIKE PROTEIN METEORIN-LIKE PROTEIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;multicellular organismal-level homeostasis#GO:0048871 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005349.1|UniProtKB=W5MDI6 W5MDI6 PTHR24291:SF119 CYTOCHROME P450 FAMILY 4 SI:CH211-113J14.1 catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;vitamin D metabolic process#GO:0042359;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006975.1|UniProtKB=W5MJ88 W5MJ88 PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A LEPOC|Ensembl=ENSLOCG00000002819.1|UniProtKB=W5M4K8 W5M4K8 PTHR11486:SF83 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 2 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;response to fibroblast growth factor#GO:0071774;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 growth factor#PC00112;intercellular signal molecule#PC00207 Angiogenesis#P00005>FGF#P00213;FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000009363.1|UniProtKB=W5MSS1 W5MSS1 PTHR10352:SF9 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 4 regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;perikaryon#GO:0043204;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cell body#GO:0044297;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000003323.1|UniProtKB=W5M6C0 W5M6C0 PTHR39313:SF1 IM:7138239 LOC100158295 PROTEIN anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;embryo development#GO:0009790 LEPOC|Ensembl=ENSLOCG00000007013.1|UniProtKB=W5MJD2 W5MJD2 PTHR15036:SF15 PIKACHURIN-LIKE PROTEIN CHONDROITIN SULFATE PROTEOGLYCAN 4B biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;developmental process#GO:0032502;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008309.1|UniProtKB=W5MNY7 W5MNY7 PTHR23280:SF13 4.1 G PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MYLIP aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000013271.1|UniProtKB=W5N6U9 W5N6U9 AHRR PTHR10649:SF3 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR REPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000015775.1|UniProtKB=W5NFK9 W5NFK9 PTHR14324:SF3 CONDENSIN-2 COMPLEX SUBUNIT H2 CONDENSIN-2 COMPLEX SUBUNIT H2 chromatin binding#GO:0003682;binding#GO:0005488 mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;mitotic sister chromatid separation#GO:0051306;sexual reproduction#GO:0019953;nuclear division#GO:0000280;chromosome condensation#GO:0030261;organelle fission#GO:0048285;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome separation#GO:0051304 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensin complex#GO:0000796 LEPOC|Ensembl=ENSLOCG00000016767.1|UniProtKB=W5NJB7 W5NJB7 PTHR24073:SF263 DRAB5-RELATED RAB-LIKE PROTEIN 2A-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014617.1|UniProtKB=W5NBI4 W5NBI4 PTHR15711:SF15 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 3 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 developmental process#GO:0032502;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;establishment of cell polarity#GO:0030010;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;cell development#GO:0048468;cell differentiation#GO:0030154;epithelium development#GO:0060429;cell morphogenesis#GO:0000902;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GTPase-activating protein#PC00257;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000005097.1|UniProtKB=W5MCN0 W5MCN0 PTHR10913:SF80 FOLLISTATIN-RELATED TOMOREGULIN-2 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000017367.1|UniProtKB=W5NLG3 W5NLG3 PTHR15283:SF2 GREMLIN 1 GREMLIN-2 molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000012504.1|UniProtKB=W5N432 W5N432 PTHR24341:SF5 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN ENGRAILED-2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000007128.1|UniProtKB=W5MJS0 W5MJS0 PTHR23113:SF197 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1B molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000011500.1|UniProtKB=W5N0H4 W5N0H4 PTHR11329:SF2 LEUKOCYTE CELL-DERIVED CHEMOTAXIN 2 LEUKOCYTE CELL DERIVED CHEMOTAXIN 2, TANDEM DUPLICATE 1-RELATED cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000011956.1|UniProtKB=W5N245 W5N245 PTHR47958:SF103 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX41-RELATED nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000012594.1|UniProtKB=W5N4E3 W5N4E3 PTHR13419:SF1 ZINC FINGER-CONTAINING CXXC-TYPE ZINC FINGER PROTEIN 4 DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000012477.1|UniProtKB=W5N404 W5N404 PTHR14991:SF0 RING FINGER PROTEIN 32 RING FINGER PROTEIN 32 LEPOC|Ensembl=ENSLOCG00000017303.1|UniProtKB=W5NL99 W5NL99 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012101.1|UniProtKB=W5N2N1 W5N2N1 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of canonical Wnt signaling pathway#GO:0060828;signal transduction#GO:0007165;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 LEPOC|Ensembl=ENSLOCG00000005711.1|UniProtKB=W5MEV4 W5MEV4 TARBP2 PTHR46205:SF1 LOQUACIOUS, ISOFORM B RISC-LOADING COMPLEX SUBUNIT TARBP2 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;siRNA processing#GO:0030422;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of gene silencing by regulatory ncRNA#GO:0060966;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010916.1|UniProtKB=W5MYC8 W5MYC8 PTHR23036:SF96 CYTOKINE RECEPTOR INTERLEUKIN-31 RECEPTOR SUBUNIT ALPHA transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375 cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008253.1|UniProtKB=W5MNR9 W5MNR9 PTHR43073:SF5 DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076 metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;dehydrogenase#PC00092 Pyrimidine Metabolism#P02771>Dihydrouracil Dehydrogenase#P03128 LEPOC|Ensembl=ENSLOCG00000011187.1|UniProtKB=W5MZD5 W5MZD5 PTHR28556:SF7 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106B bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852 LEPOC|Ensembl=ENSLOCG00000001403.1|UniProtKB=W5LZN9 W5LZN9 PTHR11538:SF26 PHENYLALANYL-TRNA SYNTHETASE FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1 N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a rRNA#GO:0140102;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649 tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;translation#GO:0006412;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;protein metabolic process#GO:0019538;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;rRNA base methylation#GO:0070475;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;RNA processing#GO:0006396;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;rRNA modification#GO:0000154;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA metabolic process#GO:0016070;methylation#GO:0032259 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000018367.1|UniProtKB=W5NPA9 W5NPA9 PTHR13259:SF1 BLADDER CANCER 10 KD PROTEIN HOMOLOG APOPTOSIS INDUCING FACTOR BLCAP LEPOC|Ensembl=ENSLOCG00000010625.1|UniProtKB=W5MXA3 W5MXA3 PTHR46208:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007042.1|UniProtKB=W5MJI2 W5MJI2 PTHR24416:SF505 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 3 catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;fibroblast growth factor binding#GO:0017134;transferase activity#GO:0016740;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to fibroblast growth factor#GO:0071774;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 LEPOC|Ensembl=ENSLOCG00000008776.1|UniProtKB=W5MQM2 W5MQM2 PTHR46479:SF1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;lysosome localization#GO:0032418;cellular process#GO:0009987;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907;organelle localization#GO:0051640 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;BLOC-1 complex#GO:0031083;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000000771.1|UniProtKB=W5LXJ7 W5LXJ7 PTHR23351:SF6 FOS TRANSCRIPTION FACTOR-RELATED FOS-RELATED ANTIGEN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000016233.1|UniProtKB=W5NHA6 W5NHA6 PTHR10190:SF17 EYES ABSENT PROTEIN PHOSPHATASE EYA4 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;animal gross anatomical part developmental process#GO:0160108;ear development#GO:0043583;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;regulation of DNA metabolic process#GO:0051052;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of response to stress#GO:0080134;sensory organ development#GO:0007423;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;inner ear development#GO:0048839;regulation of primary metabolic process#GO:0080090;positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;positive regulation of DNA metabolic process#GO:0051054;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000011592.1|UniProtKB=W5N0T0 W5N0T0 PTHR21043:SF0 IOJAP SUPERFAMILY ORTHOLOG MITOCHONDRIAL ASSEMBLY OF RIBOSOMAL LARGE SUBUNIT PROTEIN 1 ribonucleoprotein complex binding#GO:0043021;ribosomal large subunit binding#GO:0043023;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488 membraneless organelle assembly#GO:0140694;mitochondrial large ribosomal subunit assembly#GO:1902775;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;protein-RNA complex assembly#GO:0022618;ribosomal large subunit assembly#GO:0000027;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mitochondrial ribosome assembly#GO:0061668 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000017217.1|UniProtKB=W5NKX8 W5NKX8 PTHR11475:SF75 OXIDASE/PEROXIDASE PEROXIDASIN HOMOLOG peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000004507.1|UniProtKB=W5MAI2 W5MAI2 PTHR11686:SF54 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 7 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007668.1|UniProtKB=W5MLQ4 W5MLQ4 PTHR12296:SF32 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN 3 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;localization#GO:0051179;cellular localization#GO:0051641;regulation of signaling#GO:0023051;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;regulation of response to stimulus#GO:0048583;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000015185.1|UniProtKB=W5NDH6 W5NDH6 PTHR24031:SF781 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX56-RELATED macromolecule biosynthetic process#GO:0009059;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;response to other organism#GO:0051707;maturation of LSU-rRNA#GO:0000470;rRNA metabolic process#GO:0016072;response to external stimulus#GO:0009605;defense response#GO:0006952;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to external biotic stimulus#GO:0043207;RNA biosynthetic process#GO:0032774;rRNA processing#GO:0006364;response to virus#GO:0009615;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;defense response to virus#GO:0051607;biological process involved in interspecies interaction between organisms#GO:0044419;ribonucleoprotein complex biogenesis#GO:0022613;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005706.1|UniProtKB=W5MEV5 W5MEV5 PTHR22529:SF1 EPITHELIAL-STROMAL INTERACTION PROTEIN 1 EPITHELIAL-STROMAL INTERACTION PROTEIN 1 cellular process#GO:0009987;response to stress#GO:0006950;leukocyte activation#GO:0045321;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;myeloid leukocyte activation#GO:0002274;cell activation#GO:0001775;inflammatory response#GO:0006954;immune system process#GO:0002376;defense response#GO:0006952;macrophage activation#GO:0042116 LEPOC|Ensembl=ENSLOCG00000014939.1|UniProtKB=W5NCN5 W5NCN5 PTHR10309:SF0 MANNOSE-6-PHOSPHATE ISOMERASE MANNOSE-6-PHOSPHATE ISOMERASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;organophosphate biosynthetic process#GO:0090407 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Mannose metabolism#P02752>Mannose 6-P isomerase#P03017 LEPOC|Ensembl=ENSLOCG00000004755.1|UniProtKB=W5MBE3 W5MBE3 PTHR42923:SF3 PROTOPORPHYRINOGEN OXIDASE PROTOPORPHYRINOGEN OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 Heme biosynthesis#P02746>Protoporphyrinogen oxidase#P02976 LEPOC|Ensembl=ENSLOCG00000003429.1|UniProtKB=W5M6Q3 W5M6Q3 PTHR35079:SF1 LUNG ADENOMA SUSCEPTIBILITY PROTEIN 2 LUNG ADENOMA SUSCEPTIBILITY PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000015455.1|UniProtKB=W5NEG2 W5NEG2 PTHR24409:SF451 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 431-LIKE DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000015771.1|UniProtKB=W5NFK6 W5NFK6 PTHR46917:SF1 MORN REPEAT-CONTAINING PROTEIN 2 MORN REPEAT-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000002126.1|UniProtKB=W5M268 W5M268 PTHR13423:SF2 OUT AT FIRST OUT AT FIRST PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000015663.1|UniProtKB=W5NF73 W5NF73 PTHR10606:SF41 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 3 sugar-phosphatase activity#GO:0050308;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 phosphatase#PC00181;carbohydrate phosphatase#PC00066;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004017.1|UniProtKB=W5M8U0 W5M8U0 PTHR46311:SF3 CALCIUM-BINDING PROTEIN 8-RELATED CALCIUM-BINDING PROTEIN 8 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;organelle#GO:0043226;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000002665.1|UniProtKB=W5M434 W5M434 PTHR13112:SF2 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN REGULATOR OF NONSENSE TRANSCRIPTS 3A sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;RNA binding#GO:0003723;DNA binding#GO:0003677;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;positive regulation of macromolecule metabolic process#GO:0010604;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;positive regulation of protein metabolic process#GO:0051247;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000014973.1|UniProtKB=W5NCS8 W5NCS8 PTHR24083:SF4 NUCLEAR HORMONE RECEPTOR PHOTORECEPTOR-SPECIFIC NUCLEAR RECEPTOR sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000004515.1|UniProtKB=W5MAJ1 W5MAJ1 PTHR10489:SF671 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 3 cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;chemotaxis#GO:0006935;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell communication#GO:0007154 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000004676.1|UniProtKB=W5MBB1 W5MBB1 PTHR45691:SF9 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 3 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036 intracellular organelle#GO:0043229;actin filament#GO:0005884;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 LEPOC|Ensembl=ENSLOCG00000004517.1|UniProtKB=W5MAJ9 W5MAJ9 PTHR23086:SF26 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 GAMMA catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 kinase#PC00137;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000014821.1|UniProtKB=W5NC93 W5NC93 PTHR15468:SF2 ZNF185 ZINC FINGER PROTEIN 185 LEPOC|Ensembl=ENSLOCG00000002081.1|UniProtKB=W5M207 W5M207 PTHR12610:SF23 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 2 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002763.1|UniProtKB=W5M4E2 W5M4E2 PTHR32179:SF3 NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carboxylic acid catabolic process#GO:0046395;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165 LEPOC|Ensembl=ENSLOCG00000008084.1|UniProtKB=W5MN71 W5MN71 PTHR33721:SF4 TRANSMEMBRANE PROTEIN 255B-LIKE TRANSMEMBRANE PROTEIN 255B LEPOC|Ensembl=ENSLOCG00000012804.1|UniProtKB=W5N548 W5N548 PTHR22950:SF646 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 38 MEMBER 10 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 LEPOC|Ensembl=ENSLOCG00000002956.1|UniProtKB=W5M528 W5M528 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000002762.1|UniProtKB=W5M4E1 W5M4E1 PTHR45476:SF5 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL 4-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000018250.1|UniProtKB=W5NNZ2 W5NNZ2 PTHR24366:SF46 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT NEURONAL 1 L HOMEOLOG PRECURSOR immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005902.1|UniProtKB=W5MFH0 W5MFH0 PTHR10947:SF3 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000014941.1|UniProtKB=W5NCP0 W5NCP0 PTHR10687:SF7 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 2 cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;secretion by cell#GO:0032940;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179 Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000012273.1|UniProtKB=W5N391 W5N391 PTHR10885:SF24 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720 peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 isomerase#PC00135 LEPOC|Ensembl=ENSLOCG00000002740.1|UniProtKB=W5M4G6 W5M4G6 PTHR21567:SF30 CLASP CLIP-ASSOCIATING PROTEIN 2 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 nuclear division#GO:0000280;spindle localization#GO:0051653;cellular localization#GO:0051641;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;establishment of organelle localization#GO:0051656;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of mitotic spindle localization#GO:0040001;spindle assembly#GO:0051225;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle assembly#GO:0070925;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;spindle organization#GO:0007051;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;mitotic sister chromatid segregation#GO:0000070;establishment of spindle localization#GO:0051293;mitotic spindle assembly#GO:0090307 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;microtubule organizing center#GO:0005815;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;cell periphery#GO:0071944;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;basal part of cell#GO:0045178;cytoplasmic microtubule#GO:0005881;chromosome#GO:0005694;cell cortex#GO:0005938;kinetochore#GO:0000776 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005215.1|UniProtKB=W5MD20 W5MD20 PTHR31204:SF1 SIGMA INTRACELLULAR RECEPTOR 2 SIGMA INTRACELLULAR RECEPTOR 2 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of localization#GO:0032879;regulation of transport#GO:0051049;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000003080.1|UniProtKB=W5M5I4 W5M5I4 PTHR13269:SF6 NUCLEOPORIN NDC1 NUCLEOPORIN NDC1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nuclear pore organization#GO:0006999;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002364.1|UniProtKB=W5M327 W5M327 PTHR24289:SF19 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE CYTOCHROME P450 17A2 PRECURSOR monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 hormone biosynthetic process#GO:0042446;biosynthetic process#GO:0009058;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;hormone metabolic process#GO:0042445;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180;regulation of biological quality#GO:0065008;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;olefinic compound metabolic process#GO:0120254 LEPOC|Ensembl=ENSLOCG00000002493.1|UniProtKB=W5M3H6 W5M3H6 PTHR24061:SF441 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 2.1-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010381.1|UniProtKB=W5MWG2 W5MWG2 PTHR24410:SF24 HL07962P-RELATED BTB (POZ) DOMAIN CONTAINING 6B defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015424.1|UniProtKB=W5NEC7 W5NEC7 PTHR11905:SF32 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 28 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000005927.1|UniProtKB=W5MFJ7 W5MFJ7 PTHR10372:SF8 PLAKOPHILLIN-RELATED PLAKOPHILIN-4 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227 intermediate filament binding protein#PC00130;cytoskeletal protein#PC00085;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000011168.1|UniProtKB=W5MZC0 W5MZC0 PTHR12207:SF25 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006535.1|UniProtKB=W5MHP1 W5MHP1 PTHR12560:SF7 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 ceramide metabolic process#GO:0006672;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007023.1|UniProtKB=W5MJE3 W5MJE3 PTHR46059:SF2 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 1 glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000008510.1|UniProtKB=W5MPP7 W5MPP7 PTHR11645:SF72 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE 3 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 reductase#PC00198;metabolite interconversion enzyme#PC00262 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 LEPOC|Ensembl=ENSLOCG00000011885.1|UniProtKB=W5N1V8 W5N1V8 PTHR10751:SF15 GUANYLATE BINDING PROTEIN ATLASTIN-1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 G-protein#PC00020;heterotrimeric G-protein#PC00117 LEPOC|Ensembl=ENSLOCG00000013060.1|UniProtKB=W5N634 W5N634 PTHR12135:SF3 DNA REPAIR PROTEIN XP-C / RAD4 DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleotide-excision repair complex#GO:0000109;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000003738.1|UniProtKB=W5M7U3 W5M7U3 PTHR24322:SF755 PKSB RETINOL DEHYDROGENASE 10 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000020988.1|UniProtKB=Q8HQM7 Q8HQM7 PTHR11403:SF7 CYTOCHROME C OXIDASE SUBUNIT III CYTOCHROME C OXIDASE SUBUNIT 3 monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075 aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000009349.1|UniProtKB=W5MSQ0 W5MSQ0 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009433.1|UniProtKB=W5MSZ9 W5MSZ9 PTHR10177:SF63 CYCLINS CYCLIN-J-LIKE PROTEIN enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047 membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000005999.1|UniProtKB=W5MFU1 W5MFU1 PTHR46712:SF1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 LEPOC|Ensembl=ENSLOCG00000016631.1|UniProtKB=W5NIU3 W5NIU3 PTHR10166:SF59 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-4 gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000000999.1|UniProtKB=W5LYB5 W5LYB5 PTHR47229:SF1 TRANSMEMBRANE PROTEIN 141 TRANSMEMBRANE PROTEIN 141 LEPOC|Ensembl=ENSLOCG00000003043.1|UniProtKB=W5M5D6 W5M5D6 PTHR15934:SF4 RNA 2',3'-CYCLIC PHOSPHODIESTERASE A-KINASE ANCHOR PROTEIN 7-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN protein kinase A binding#GO:0051018;binding#GO:0005488;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008805.1|UniProtKB=W5MQR1 W5MQR1 PTHR10073:SF54 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL PMS1 PROTEIN HOMOLOG 1 DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520 cellular process#GO:0009987;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000018077.1|UniProtKB=W5NNG9 W5NNG9 PTHR14819:SF5 GTP-BINDING INTERFERON-INDUCED VERY LARGE GTPASE 1 LEPOC|Ensembl=ENSLOCG00000002788.1|UniProtKB=W5M4H1 W5M4H1 PTHR15599:SF1 RTDR1 RADIAL SPOKE HEAD 14 HOMOLOG LEPOC|Ensembl=ENSLOCG00000011198.1|UniProtKB=W5MZF6 W5MZF6 PTHR11476:SF7 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008857.1|UniProtKB=W5MQW6 W5MQW6 PTHR23285:SF2 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3A RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003617.1|UniProtKB=W5M7D9 W5M7D9 PTHR10953:SF5 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 2 ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity, transferring sulphur-containing groups#GO:0016782;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;ligase activity#GO:0016874;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000006788.1|UniProtKB=W5MIK1 W5MIK1 PTHR11802:SF502 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE LYSOSOMAL PROTECTIVE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000014860.1|UniProtKB=W5NCD7 W5NCD7 PTHR14499:SF30 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING 12B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of cell communication#GO:0010646;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cell junction#GO:0030054;presynaptic active zone#GO:0048786;presynaptic active zone membrane#GO:0048787;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic membrane#GO:0045211 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005183.1|UniProtKB=W5MCY2 W5MCY2 PTHR31108:SF6 TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN TUMOR PROTEIN P63-REGULATED GENE 1 PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014857.1|UniProtKB=W5NCD6 W5NCD6 PTHR24112:SF68 LEUCINE-RICH REPEAT, ISOFORM F-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 37 cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell migration#GO:0016477;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000016037.1|UniProtKB=W5NGJ3 W5NGJ3 PTHR24073:SF963 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1A hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell body#GO:0044297 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000000692.1|UniProtKB=W5LXB2 W5LXB2 PTHR21685:SF3 TON-B BOX DOMAIN TAPERIN LEPOC|Ensembl=ENSLOCG00000015618.1|UniProtKB=W5NF18 W5NF18 PTHR48277:SF1 MITOCHONDRIAL RIBOSOMAL PROTEIN S5 SMALL RIBOSOMAL SUBUNIT PROTEIN US5M LEPOC|Ensembl=ENSLOCG00000013694.1|UniProtKB=W5N8C4 W5N8C4 PTHR12902:SF9 WASP-1 WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER protein kinase A regulatory subunit binding#GO:0034237;protein kinase A binding#GO:0051018;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 intracellular anatomical structure#GO:0005622;lamellipodium#GO:0030027;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000000918.1|UniProtKB=W5LY17 W5LY17 PTHR10339:SF32 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 5-RELATED glycosyltransferase activity#GO:0016757;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015470.1|UniProtKB=W5NEI1 W5NEI1 PTHR11937:SF389 ACTIN ACTIN ALPHA 1, SKELETAL MUSCLE B structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Cadherin signaling pathway#P00012>F-actin#P00470;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 LEPOC|Ensembl=ENSLOCG00000017791.1|UniProtKB=W5NMN6 W5NMN6 PTHR12002:SF228 CLAUDIN CLAUDIN-RELATED cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840 anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000009303.1|UniProtKB=W5MSJ1 W5MSJ1 PTHR46627:SF1 AMINOPEPTIDASE O AMINOPEPTIDASE O organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011639.1|UniProtKB=W5N0Z2 W5N0Z2 PTHR43684:SF5 FAMILY NOT NAMED CHROMODOMAIN Y-LIKE PROTEIN transcription regulator activity#GO:0140110;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;isomerase activity#GO:0016853;chromatin-protein adaptor activity#GO:0140463;intramolecular oxidoreductase activity#GO:0016860;histone H3K9me2/3 reader activity#GO:0062072;histone reader activity#GO:0140566;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090 monocarboxylic acid catabolic process#GO:0072329;male gamete generation#GO:0048232;carboxylic acid catabolic process#GO:0046395;cellular developmental process#GO:0048869;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;developmental process#GO:0032502;spermatogenesis#GO:0007283;fatty acid metabolic process#GO:0006631;reproductive process#GO:0022414;catabolic process#GO:0009056;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;lipid oxidation#GO:0034440;spermatid development#GO:0007286;sexual reproduction#GO:0019953;cellular process#GO:0009987;lipid catabolic process#GO:0016042;fatty acid oxidation#GO:0019395;metabolic process#GO:0008152;cellular process involved in reproduction in multicellular organism#GO:0022412;small molecule catabolic process#GO:0044282;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;spermatid differentiation#GO:0048515;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;nucleus#GO:0005634;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001904.1|UniProtKB=W5M1E3 W5M1E3 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000361.1|UniProtKB=W5LW89 W5LW89 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003913.1|UniProtKB=W5M8G7 W5M8G7 PTHR11923:SF112 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 LYSOSOME MEMBRANE PROTEIN 2C cargo receptor activity#GO:0038024 protein localization to lysosome#GO:0061462;establishment of protein localization to vacuole#GO:0072666;endocytosis#GO:0006897;protein localization to organelle#GO:0033365;protein targeting#GO:0006605;lysosomal transport#GO:0007041;protein localization to vacuole#GO:0072665;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;intracellular protein localization#GO:0008104 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000002508.1|UniProtKB=W5M3K2 W5M3K2 PTHR31488:SF1 DPY-19-LIKE 1, LIKE (H. SAPIENS) DPY-19 LIKE C-MANNOSYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000009400.1|UniProtKB=W5MSW7 W5MSW7 PTHR10404:SF81 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2 catalytic activity#GO:0003824;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000009854.1|UniProtKB=W5MUI6 W5MUI6 PTHR14987:SF3 PROTEIN LBH-RELATED LBH DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000002704.1|UniProtKB=W5M475 W5M475 PTHR13318:SF44 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 2 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461 LEPOC|Ensembl=ENSLOCG00000001966.1|UniProtKB=W5M1M3 W5M1M3 PTHR46042:SF1 DIPHTHINE METHYLTRANSFERASE DIPHTHINE METHYLTRANSFERASE cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000009861.1|UniProtKB=W5MUJ3 W5MUJ3 PTHR13580:SF10 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE_SERINE-RICH NUCLEAR PROTEIN 1 DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014127.1|UniProtKB=W5N9V5 W5N9V5 PTHR13484:SF9 FIP1-LIKE 1 PROTEIN PRE-MRNA 3'-END-PROCESSING FACTOR FIP1 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001709.1|UniProtKB=W5M0R4 W5M0R4 PTHR47977:SF124 RAS-RELATED PROTEIN RAB RAB1B, MEMBER RAS ONCO FAMILY ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000009714.1|UniProtKB=W5MU01 W5MU01 PTHR14386:SF2 PROTEIN FAM204A PROTEIN FAM204A LEPOC|Ensembl=ENSLOCG00000013062.1|UniProtKB=W5N630 W5N630 PTHR31034:SF2 TRANSMEMBRANE PROTEIN 101 TRANSMEMBRANE PROTEIN 101 LEPOC|Ensembl=ENSLOCG00000005636.1|UniProtKB=W5MEK5 W5MEK5 PTHR13817:SF89 TITIN MYOMESIN-3 structural molecule activity#GO:0005198 striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;cell development#GO:0048468;actomyosin structure organization#GO:0031032;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001 M band#GO:0031430;intracellular organelle#GO:0043229;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;A band#GO:0031672;contractile muscle fiber#GO:0043292;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016039.1|UniProtKB=W5NGK1 W5NGK1 PTHR15859:SF2 SETA BINDING PROTEIN 1 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD3 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011124.1|UniProtKB=W5MZ54 W5MZ54 PTHR10424:SF81 VIRAL ENVELOPE PROTEIN ENVELOPE GLYCOPROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000016066.1|UniProtKB=W5NGP1 W5NGP1 PTHR11933:SF9 TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;sulfurtransferase activity#GO:0016783 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble position uridine thiolation#GO:0002143;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;tRNA thio-modification#GO:0034227;mitochondrial gene expression#GO:0140053;mitochondrial RNA modification#GO:1900864;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000014291.1|UniProtKB=W5NAD9 W5NAD9 PTHR12419:SF58 OTU DOMAIN CONTAINING PROTEIN BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE TRANSFERASE AND DEUBIQUITINASE ALG13 ISOFORM X1 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000002303.1|UniProtKB=W5M2U7 W5M2U7 PTHR11969:SF4 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000009428.1|UniProtKB=W5MSZ8 W5MSZ8 PTHR12654:SF33 BILE ACID BETA-GLUCOSIDASE-RELATED NON-LYSOSOMAL GLUCOSYLCERAMIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;catalytic activity#GO:0003824 system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501 glucosidase#PC00108;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015210.1|UniProtKB=W5NDK8 W5NDK8 PTHR11662:SF207 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER 3 carboxylic acid transmembrane transporter activity#GO:0046943;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of synapse structure or activity#GO:0050803;cellular localization#GO:0051641;cell communication#GO:0007154;localization#GO:0051179;regulation of biological quality#GO:0065008;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;presynapse#GO:0098793;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054 secondary carrier transporter#PC00258 Ionotropic glutamate receptor pathway#P00037>Vglut#P01021 LEPOC|Ensembl=ENSLOCG00000006539.1|UniProtKB=W5MHP2 W5MHP2 PTHR43668:SF2 ALLANTOINASE ALLANTOINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;purine nucleobase catabolic process#GO:0006145;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112 hydrolase#PC00121 Allantoin degradation#P02725>Allantoinase#P02822;De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydroorotase#P02928 LEPOC|Ensembl=ENSLOCG00000009506.1|UniProtKB=W5MTB3 W5MTB3 PTHR10127:SF838 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000014311.1|UniProtKB=W5NAG4 W5NAG4 PTHR15592:SF20 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000007779.1|UniProtKB=W5MM51 W5MM51 PTHR22974:SF22 MIXED LINEAGE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TOUSLED-LIKE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 chromosome segregation#GO:0007059;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000014851.1|UniProtKB=W5NCE0 W5NCE0 PTHR22870:SF155 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC1-RELATED guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000008517.1|UniProtKB=W5MPQ6 W5MPQ6 PTHR46613:SF1 RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED LEPOC|Ensembl=ENSLOCG00000010261.1|UniProtKB=W5MW04 W5MW04 PTHR11360:SF24 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 1 proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;monocarboxylic acid transmembrane transporter activity#GO:0008028;solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic cation transmembrane transporter activity#GO:0008324 carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004359.1|UniProtKB=W5MA08 W5MA08 PTHR11130:SF0 GLUTATHIONE SYNTHETASE GLUTATHIONE SYNTHETASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;metabolic process#GO:0008152;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000015211.1|UniProtKB=W5NDL6 W5NDL6 PTHR38487:SF1 TESTIS EXPRESSED 11 PROTEIN ZIP4 HOMOLOG LEPOC|Ensembl=ENSLOCG00000000959.1|UniProtKB=W5LY72 W5LY72 PTHR11311:SF7 SPONDIN THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 7B actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016574.1|UniProtKB=W5NIL5 W5NIL5 PTHR24240:SF197 OPSIN OPSIN-3 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signal transduction#GO:0007165;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;response to radiation#GO:0009314;detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001526.1|UniProtKB=W5M037 W5M037 PTHR22997:SF6 PIH1 DOMAIN-CONTAINING PROTEIN 1 PIH1 DOMAIN-CONTAINING PROTEIN 2 protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904 LEPOC|Ensembl=ENSLOCG00000012108.1|UniProtKB=W5N2P4 W5N2P4 PTHR11255:SF125 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE THETA catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;biological regulation#GO:0065007;signaling#GO:0023052;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 membrane#GO:0016020;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000008918.1|UniProtKB=W5MR55 W5MR55 PTHR24006:SF915 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE-RELATED hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;regulation of biological quality#GO:0065008;mitotic cell cycle process#GO:1903047;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;regulation of protein stability#GO:0031647;cell cycle#GO:0007049;biological regulation#GO:0065007;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011760.1|UniProtKB=W5N1F2 W5N1F2 PTHR11615:SF124 NITRATE, FORMATE, IRON DEHYDROGENASE NUCLEAR PRELAMIN A RECOGNITION FACTOR protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;intracellular protein-containing complex#GO:0140535;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008370.1|UniProtKB=W5MP72 W5MP72 PTHR24353:SF116 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT BETA catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 GABA-B receptor II signaling#P05731>PKA#P05752;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Endothelin signaling pathway#P00019>PKA#P00570;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-c#P00707;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;CCKR signaling map#P06959>PKA-Calpha/beta/gamma#P07099 LEPOC|Ensembl=ENSLOCG00000012737.1|UniProtKB=W5N4W2 W5N4W2 PTHR34340:SF1 MELANOREGULIN MELANOREGULIN LEPOC|Ensembl=ENSLOCG00000015533.1|UniProtKB=W5NEQ7 W5NEQ7 PTHR16155:SF18 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010814.1|UniProtKB=W5MXZ7 W5MXZ7 PTHR11814:SF17 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 9 dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;chloride transport#GO:0006821 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006214.1|UniProtKB=W5MGJ5 W5MGJ5 PTHR10285:SF66 URIDINE KINASE URIDINE-CYTIDINE KINASE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;nucleoside kinase activity#GO:0019206;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 LEPOC|Ensembl=ENSLOCG00000008278.1|UniProtKB=W5MNV2 W5MNV2 PTHR12247:SF140 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 1 ISOFORM X1 binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 protein-containing complex#GO:0032991;PcG protein complex#GO:0031519;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000013308.1|UniProtKB=W5N6Z9 W5N6Z9 PTHR10694:SF104 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4C dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;protein demethylase activity#GO:0140457;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000005680.1|UniProtKB=W5MER5 W5MER5 PTHR18966:SF417 IONOTROPIC GLUTAMATE RECEPTOR KAINATE BINDING PROTEIN-RELATED transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916 neuron projection#GO:0043005;protein-containing complex#GO:0032991;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;signaling receptor complex#GO:0043235;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;dendrite#GO:0030425;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA#P01026;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Huntington disease#P00029>Kainate receptor#P00796 LEPOC|Ensembl=ENSLOCG00000013421.1|UniProtKB=W5N7D8 W5N7D8 PTHR23268:SF128 T-CELL RECEPTOR BETA CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014773.1|UniProtKB=W5NC40 W5NC40 PTHR18916:SF77 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 3 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010 microtubule end#GO:1990752;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017741.1|UniProtKB=W5NMI6 W5NMI6 PTHR10484:SF212 HISTONE H4 HISTONE H4 structural molecule activity#GO:0005198 chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012576.1|UniProtKB=W5N4C0 W5N4C0 PTHR13594:SF2 CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA-LIKE cell projection organization#GO:0030030;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;organelle assembly#GO:0070925;centriole replication#GO:0007099;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000001969.1|UniProtKB=W5M1M6 W5M1M6 PTHR14499:SF27 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD15 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004482.1|UniProtKB=W5MAE5 W5MAE5 PTHR14334:SF1 B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN ALPHA CHAIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 B cell receptor signaling pathway#GO:0050853;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;antigen receptor-mediated signaling pathway#GO:0050851;lymphocyte activation#GO:0046649;cell surface receptor signaling pathway#GO:0007166;B cell activation#GO:0042113;immune response-activating signaling pathway#GO:0002757;mononuclear cell differentiation#GO:1903131;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;leukocyte differentiation#GO:0002521;cell development#GO:0048468;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;immune system process#GO:0002376;biological regulation#GO:0065007;hemopoiesis#GO:0030097;immune response-regulating cell surface receptor signaling pathway#GO:0002768;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cell activation#GO:0001775;regulation of immune response#GO:0050776;lymphocyte differentiation#GO:0030098;anatomical structure development#GO:0048856;cell communication#GO:0007154 signaling receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 B cell activation#P00010>Ig-alpha#P00399 LEPOC|Ensembl=ENSLOCG00000003268.1|UniProtKB=W5M648 W5M648 DBI PTHR23310:SF62 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000009179.1|UniProtKB=W5MS35 W5MS35 PTHR24180:SF14 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 45 cellular process#GO:0009987;cell population proliferation#GO:0008283 cellular anatomical structure#GO:0110165;midbody#GO:0030496 kinase inhibitor#PC00139;kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000001897.1|UniProtKB=W5M1G6 W5M1G6 PTHR23280:SF27 4.1 G PROTEIN TYROSINE-PROTEIN PHOSPHATASE actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000015825.1|UniProtKB=W5NFS0 W5NFS0 PTHR47979:SF46 DRAB11-RELATED RAS-RELATED PROTEIN RAB-39A guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012893.1|UniProtKB=W5N5I0 W5N5I0 PTHR18966:SF109 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089 trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267 dendritic spine#GO:0043197;postsynapse#GO:0098794;neuron spine#GO:0044309;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;neuron projection#GO:0043005;protein-containing complex#GO:0032991;synaptic membrane#GO:0097060;transporter complex#GO:1990351;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;dendrite#GO:0030425;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005554.1|UniProtKB=W5ME99 W5ME99 PTHR23291:SF112 BAX INHIBITOR-RELATED GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;mitochondrial calcium ion transmembrane transport#GO:0006851;organelle organization#GO:0006996;monoatomic ion transmembrane transport#GO:0034220;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 cytoplasm#GO:0005737;endomembrane system#GO:0012505;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000009659.1|UniProtKB=W5MTU3 W5MTU3 PTHR24412:SF512 KELCH PROTEIN KELCH-LIKE PROTEIN 40A-RELATED ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011412.1|UniProtKB=W5N084 W5N084 PTHR46767:SF1 LIM DOMAIN ONLY PROTEIN 7 LIM DOMAIN ONLY PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000002208.1|UniProtKB=W5M2G1 W5M2G1 PTHR13085:SF0 MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 2 protein metabolic process#GO:0019538;localization#GO:0051179;protein targeting#GO:0006605;primary metabolic process#GO:0044238;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;protein targeting to ER#GO:0045047;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;establishment of protein localization to endoplasmic reticulum#GO:0072599;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of protein localization#GO:0045184 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 LEPOC|Ensembl=ENSLOCG00000012544.1|UniProtKB=W5N489 W5N489 PTHR33775:SF1 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED PROLINE-RICH BASIC PROTEIN 1 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010408.1|UniProtKB=W5MWK5 W5MWK5 PTHR34098:SF1 F-BOX ONLY PROTEIN 47 F-BOX ONLY PROTEIN 47 LEPOC|Ensembl=ENSLOCG00000011113.1|UniProtKB=W5MZ43 W5MZ43 PTHR15114:SF1 REPLICATION PROTEIN A3 REPLICATION PROTEIN A 14 KDA SUBUNIT nucleic acid binding#GO:0003676;binding#GO:0005488;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-DNA complex#GO:0032993;organelle#GO:0043226;replication fork#GO:0005657;replisome#GO:0030894;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 Cell cycle#P00013>Pre-replication Complex#P00478 LEPOC|Ensembl=ENSLOCG00000013223.1|UniProtKB=W5N6N5 W5N6N5 PTHR31784:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 microtubule-based transport#GO:0099111;cellular localization#GO:0051641;response to stimulus#GO:0050896;cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656;microtubule-based process#GO:0007017;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;developmental pigmentation#GO:0048066;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;cellular pigmentation#GO:0033059;organelle transport along microtubule#GO:0072384;axonal transport#GO:0098930;organelle localization#GO:0051640;pigmentation#GO:0043473;localization#GO:0051179;anterograde axonal transport#GO:0008089;cellular response to stimulus#GO:0051716;microtubule-based movement#GO:0007018;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;anterograde synaptic vesicle transport#GO:0048490;response to external stimulus#GO:0009605;vesicle cytoskeletal trafficking#GO:0099518;axo-dendritic transport#GO:0008088;vesicle localization#GO:0051648;developmental maturation#GO:0021700;cytoskeleton-dependent intracellular transport#GO:0030705 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;BLOC-1 complex#GO:0031083 LEPOC|Ensembl=ENSLOCG00000012836.1|UniProtKB=W5N594 W5N594 PTHR19282:SF120 TETRASPANIN TETRASPANIN-36 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004262.1|UniProtKB=W5M9P8 W5M9P8 PTHR10582:SF4 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873 actin filament-based process#GO:0030029;cellular response to osmotic stress#GO:0071470;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;osmosensory signaling pathway#GO:0007231;calcium ion import#GO:0070509;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;actin cytoskeleton organization#GO:0030036;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to osmotic stress#GO:0006970;transport#GO:0006810;actin filament organization#GO:0007015;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;cellular component organization#GO:0016043;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;import across plasma membrane#GO:0098739;response to stimulus#GO:0050896;calcium ion transport#GO:0006816;cellular component organization or biogenesis#GO:0071840;cellular response to chemical stress#GO:0062197;calcium ion transmembrane import into cytosol#GO:0097553;cellular response to abiotic stimulus#GO:0071214;import into cell#GO:0098657;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;cytoskeleton organization#GO:0007010;monoatomic cation transmembrane transport#GO:0098655;response to chemical#GO:0042221 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017035.1|UniProtKB=W5NK96 W5NK96 PTHR12072:SF4 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000002088.1|UniProtKB=W5M219 W5M219 PTHR14477:SF1 CUB DOMAIN-CONTAINING PROTEIN 1 CUB DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011544.1|UniProtKB=W5N0M3 W5N0M3 PTHR23192:SF29 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 2A cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000012508.1|UniProtKB=W5N448 W5N448 PTHR10516:SF26 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5 cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013177.1|UniProtKB=W5N6G9 W5N6G9 PTHR11691:SF62 TYPE I INTERFERON INTERFERON PHI 2-RELATED biological regulation#GO:0065007;adaptive immune response#GO:0002250;response to other organism#GO:0051707;multicellular organismal process#GO:0032501;immune response#GO:0006955;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;T cell activation involved in immune response#GO:0002286;response to cytokine#GO:0034097;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;defense response to other organism#GO:0098542;signal transduction#GO:0007165;lymphocyte activation involved in immune response#GO:0002285;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;B cell activation#GO:0042113;natural killer cell activation#GO:0030101;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;leukocyte activation involved in immune response#GO:0002366;humoral immune response#GO:0006959;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;cell activation involved in immune response#GO:0002263;response to peptide#GO:1901652;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;B cell activation involved in immune response#GO:0002312 interferon superfamily#PC00127;cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000001884.1|UniProtKB=W5M1D1 W5M1D1 PTHR11785:SF73 AMINO ACID TRANSPORTER ASC-TYPE AMINO ACID TRANSPORTER 1 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;L-amino acid transmembrane transporter activity#GO:0015179 carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;transport#GO:0006810;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;alanine transport#GO:0032328 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017771.1|UniProtKB=W5NML6 W5NML6 PTHR24232:SF25 G-PROTEIN COUPLED RECEPTOR S-GERANYLGERANYL-GLUTATHIONE RECEPTOR P2RY8 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005320.1|UniProtKB=W5MDF5 W5MDF5 PTHR43814:SF1 ARGININOSUCCINATE LYASE ARGININOSUCCINATE LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lyase#PC00144 Arginine biosynthesis#P02728>argininosuccinate lyase#P02841 LEPOC|Ensembl=ENSLOCG00000007624.1|UniProtKB=W5MLJ0 W5MLJ0 PTHR43289:SF2 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of immune response#GO:0050778;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;positive regulation of cellular component biogenesis#GO:0044089;regulation of response to external stimulus#GO:0032101;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of response to external stimulus#GO:0032103;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000006719.1|UniProtKB=W5MIA4 W5MIA4 PTHR12281:SF6 RP42 RELATED DCN1-LIKE PROTEIN 5 protein binding#GO:0005515;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of protein modification by small protein conjugation or removal#GO:1903320;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;regulation of protein modification process#GO:0031399;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008925.1|UniProtKB=W5MR65 W5MR65 PTHR13466:SF4 TEX2 PROTEIN-RELATED SMP-LTD DOMAIN-CONTAINING PROTEIN lipid binding#GO:0008289;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013169.1|UniProtKB=W5N6G3 W5N6G3 PTHR24039:SF48 FIBRILLIN-RELATED CD93 MOLECULE structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000009851.1|UniProtKB=W5MUK5 W5MUK5 PTHR43690:SF40 NARDILYSIN NARDILYSIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015092.1|UniProtKB=W5ND64 W5ND64 PTHR34441:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010116.1|UniProtKB=W5MVH1 W5MVH1 PTHR22846:SF52 WD40 REPEAT PROTEIN F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN TBL1X transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transcription repressor complex#GO:0017053;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118 Wnt signaling pathway#P00057>Ebi#P01453 LEPOC|Ensembl=ENSLOCG00000013644.1|UniProtKB=W5N862 W5N862 PTHR46946:SF1 NEURITE EXTENSION AND MIGRATION FACTOR NEURITE EXTENSION AND MIGRATION FACTOR negative regulation of cell adhesion#GO:0007162;negative regulation of cell-cell adhesion#GO:0022408;regulation of cell adhesion#GO:0030155;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;regulation of locomotion#GO:0040012;regulation of neuron migration#GO:2001222;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of cell motility#GO:2000145;regulation of cell-matrix adhesion#GO:0001952 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000017034.1|UniProtKB=W5NK94 W5NK94 PTHR46375:SF7 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13-RELATED KELCH-LIKE PROTEIN 42 LEPOC|Ensembl=ENSLOCG00000011637.1|UniProtKB=W5N0Z1 W5N0Z1 PTHR10466:SF1 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE 1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868 protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 mutase#PC00160;metabolite interconversion enzyme#PC00262;isomerase#PC00135 Mannose metabolism#P02752>P-Mannose mutase#P03019 LEPOC|Ensembl=ENSLOCG00000017613.1|UniProtKB=W5NM59 W5NM59 PTHR24247:SF182 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M1 molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;acetylcholine receptor activity#GO:0015464;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to chemical#GO:0042221;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;trans-synaptic signaling#GO:0099537;response to oxygen-containing compound#GO:1901700;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>mAChR1/3#P01069;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000016518.1|UniProtKB=W5NIE4 W5NIE4 PTHR34916:SF1 GI:13385330 RIKEN CDNA 1700010I14 GENE LEPOC|Ensembl=ENSLOCG00000007726.1|UniProtKB=W5MLX6 W5MLX6 PTHR21595:SF1 PATRONIN CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 2 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein depolymerization#GO:1901880;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;negative regulation of cytoskeleton organization#GO:0051494;microtubule cytoskeleton organization#GO:0000226;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;cytoplasmic microtubule organization#GO:0031122;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;cellular component organization#GO:0016043;negative regulation of organelle organization#GO:0010639 microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752 LEPOC|Ensembl=ENSLOCG00000000744.1|UniProtKB=W5LXJ4 W5LXJ4 PTHR22826:SF104 RHO GUANINE EXCHANGE FACTOR-RELATED TRIPLE FUNCTIONAL DOMAIN PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902 membrane#GO:0016020;extrinsic component of membrane#GO:0019898;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000014292.1|UniProtKB=W5NAE3 W5NAE3 PTHR11085:SF6 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2 catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;transferase activity#GO:0016740;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993;acyltransferase activity#GO:0016746 heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleolus organization#GO:0007000;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;nucleus organization#GO:0006997;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000015776.1|UniProtKB=W5NFL3 W5NFL3 PTHR24126:SF24 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10 LEPOC|Ensembl=ENSLOCG00000013846.1|UniProtKB=W5N8W8 W5N8W8 PTHR23355:SF30 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 1 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000009385.1|UniProtKB=W5MSV3 W5MSV3 PTHR14338:SF1 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1-LIKE 1 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000011730.1|UniProtKB=W5N1B3 W5N1B3 PTHR11938:SF151 FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE NADPH:ADRENODOXIN OXIDOREDUCTASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 steroid biosynthetic process#GO:0006694;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FdxR#P04604 LEPOC|Ensembl=ENSLOCG00000016409.1|UniProtKB=W5NI04 W5NI04 PTHR24369:SF229 ANTIGEN BSP, PUTATIVE-RELATED ADHESION MOLECULE WITH IG LIKE DOMAIN 2 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015418.1|UniProtKB=W5NEB8 W5NEB8 PTHR10663:SF344 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 3 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000017050.1|UniProtKB=W5NKB1 W5NKB1 PTHR42757:SF30 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED OBSCURIN, CYTOSKELETAL CALMODULIN AND TITIN-INTERACTING RHOGEF cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010038.1|UniProtKB=W5MV63 W5MV63 PTHR15304:SF2 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR DOMAIN-CONTAINING PROTEIN 2 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of JNK cascade#GO:0046328;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000018299.1|UniProtKB=W5NP41 W5NP41 PTHR15284:SF4 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN NUCLEAR FACTOR, INTERLEUKIN 3 REGULATED, MEMBER 2 ISOFORM X1 rhythmic process#GO:0048511;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;circadian rhythm#GO:0007623;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic leucine zipper transcription factor#PC00056;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000012506.1|UniProtKB=W5N437 W5N437 PTHR15240:SF3 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription initiation at RNA polymerase I promoter#GO:0006361;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription termination#GO:0006353;transcription by RNA polymerase I#GO:0006360;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352 membrane microdomain#GO:0098857;intracellular anatomical structure#GO:0005622;plasma membrane raft#GO:0044853;cell periphery#GO:0071944;caveola#GO:0005901;membrane#GO:0016020;membrane raft#GO:0045121;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 membrane traffic protein#PC00150 General transcription by RNA polymerase I#P00022>PTRF#P00656 LEPOC|Ensembl=ENSLOCG00000012864.1|UniProtKB=W5N5D6 W5N5D6 PTHR12898:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000000132.1|UniProtKB=W5LVL1 W5LVL1 PTHR12385:SF37 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;quaternary ammonium group transmembrane transporter activity#GO:0015651;organophosphate ester transmembrane transporter activity#GO:0015605 cellular process#GO:0009987;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;vitamin transport#GO:0051180;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000013469.1|UniProtKB=W5N7L0 W5N7L0 PTHR14435:SF2 ZINC FINGER PROTEIN 106 ZINC FINGER PROTEIN 106 LEPOC|Ensembl=ENSLOCG00000018135.1|UniProtKB=W5NNM7 W5NNM7 PTHR10903:SF168 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000000485.1|UniProtKB=W5LWN3 W5LWN3 PTHR23036:SF16 CYTOKINE RECEPTOR CYTOKINE RECEPTOR-LIKE FACTOR 1 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;response to chemical#GO:0042221;response to cytokine#GO:0034097;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of neuron apoptotic process#GO:0043524;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;signaling receptor complex#GO:0043235;extracellular protein-containing complex#GO:0140392;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004003.1|UniProtKB=W5M8R7 W5M8R7 PTHR11176:SF10 BOULE-RELATED PROTEIN BOULE-LIKE translation regulator activity#GO:0045182 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;positive regulation of translation#GO:0045727;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of translational initiation#GO:0006446;positive regulation of protein metabolic process#GO:0051247;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000819.1|UniProtKB=W5LXS4 W5LXS4 PTHR10082:SF28 INTEGRIN BETA SUBUNIT INTEGRIN BETA-1 cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;integrin binding#GO:0005178;cytokine binding#GO:0019955;binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;collagen binding#GO:0005518;laminin binding#GO:0043236;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;extracellular matrix binding#GO:0050840;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627;biological regulation#GO:0065007;cell migration#GO:0016477;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;signaling#GO:0023052;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229 signaling receptor complex#GO:0043235;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell surface#GO:0009986;anchoring junction#GO:0070161;integrin complex#GO:0008305;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;membrane protein complex#GO:0098796;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;synapse#GO:0045202;cellular anatomical structure#GO:0110165 integrin#PC00126 CCKR signaling map#P06959>ITGB1#P07113;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin beta#P00931;CCKR signaling map#P06959>ITGB1#G06984;CCKR signaling map#P06959>ITGB1#G07277;Gonadotropin-releasing hormone receptor pathway#P06664>alpha-beta integrin dimer#P06820 LEPOC|Ensembl=ENSLOCG00000005250.1|UniProtKB=W5MD64 W5MD64 PTHR46013:SF4 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-LIKE-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009721.1|UniProtKB=W5MU31 W5MU31 PTHR13800:SF15 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 6 monoatomic cation transmembrane transporter activity#GO:0008324;protein kinase activity#GO:0004672;calcium ion transmembrane transporter activity#GO:0015085;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transporter activity#GO:0005215;transferase activity#GO:0016740;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;transferase activity, transferring phosphorus-containing groups#GO:0016772;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;catalytic activity, acting on a protein#GO:0140096 transport#GO:0006810;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000005372.1|UniProtKB=W5MDM1 W5MDM1 PTHR24348:SF18 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 developmental growth#GO:0048589;mitophagy#GO:0000423;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of catabolic process#GO:0009894;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cell development#GO:0060284;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;piecemeal microautophagy of the nucleus#GO:0034727;developmental cell growth#GO:0048588;regulation of neurogenesis#GO:0050767;negative regulation of multicellular organismal process#GO:0051241;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;autophagosome assembly#GO:0000045;regulation of anatomical structure size#GO:0090066;growth#GO:0040007;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;axon extension#GO:0048675;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;neuron projection extension#GO:1990138;regulation of biological quality#GO:0065008;process utilizing autophagic mechanism#GO:0061919;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell development#GO:0048468;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;autophagy of mitochondrion#GO:0000422;developmental process#GO:0032502;macroautophagy#GO:0016236;negative regulation of cell growth#GO:0030308;plasma membrane bounded cell projection organization#GO:0120036;reticulophagy#GO:0061709;axon development#GO:0061564;response to nutrient levels#GO:0031667;regulation of nervous system development#GO:0051960;system development#GO:0048731;vacuole organization#GO:0007033;organelle assembly#GO:0070925;catabolic process#GO:0009056;regulation of developmental process#GO:0050793;negative regulation of cellular component organization#GO:0051129;response to starvation#GO:0042594;regulation of growth#GO:0040008;cell growth#GO:0016049;regulation of axonogenesis#GO:0050770;cell projection morphogenesis#GO:0048858;metabolic process#GO:0008152;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component assembly#GO:0022607;regulation of cell growth#GO:0001558;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;autophagy#GO:0006914;regulation of cell size#GO:0008361;developmental growth involved in morphogenesis#GO:0060560;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular component organization#GO:0016043;regulation of multicellular organismal development#GO:2000026;regulation of cellular component size#GO:0032535 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;intracellular organelle#GO:0043229;phagophore assembly site#GO:0000407;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007363.1|UniProtKB=W5MKP6 W5MKP6 PTHR45739:SF1 MATRIX PROTEIN, PUTATIVE-RELATED EXTRACELLULAR MATRIX ORGANIZING PROTEIN FRAS1 cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;cellular process#GO:0009987;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 LEPOC|Ensembl=ENSLOCG00000012538.1|UniProtKB=W5N483 W5N483 PTHR24217:SF10 PUTATIVE-RELATED SYNAPTOPODIN 2-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 striated muscle cell development#GO:0055002;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;actomyosin structure organization#GO:0031032;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of Rho protein signal transduction#GO:0035023;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;regulation of actin filament bundle assembly#GO:0032231;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of small GTPase mediated signal transduction#GO:0051056;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;regulation of cell communication#GO:0010646;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;regulation of supramolecular fiber organization#GO:1902903;muscle cell development#GO:0055001;positive regulation of actin filament bundle assembly#GO:0032233;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of actin filament-based process#GO:0032970;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053 intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;I band#GO:0031674;membraneless organelle#GO:0043228;sarcomere#GO:0030017;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000001975.1|UniProtKB=W5M1M9 W5M1M9 PTHR24233:SF0 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 12 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001211.1|UniProtKB=W5LZ06 W5LZ06 PTHR46334:SF1 COSTARS FAMILY PROTEIN ABRACL COSTARS FAMILY PROTEIN ABRACL regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000001095.1|UniProtKB=W5LYM8 W5LYM8 PTHR12207:SF31 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001878.1|UniProtKB=W5M1B5 W5M1B5 MED9 PTHR20844:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 9 mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002072.1|UniProtKB=W5M218 W5M218 PTHR10887:SF364 DNA2/NAM7 HELICASE FAMILY REGULATOR OF NONSENSE TRANSCRIPTS 1 catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000013019.1|UniProtKB=W5N5X8 W5N5X8 PTHR19282:SF550 TETRASPANIN TETRASPANIN-10 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003922.1|UniProtKB=W5M8H2 W5M8H2 PTHR14647:SF56 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 carbohydrate derivative biosynthetic process#GO:1901137;multicellular organism development#GO:0007275;myelination#GO:0042552;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lipid biosynthetic process#GO:0008610;nervous system development#GO:0007399;biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ceramide metabolic process#GO:0006672;anatomical structure development#GO:0048856;glycolipid biosynthetic process#GO:0009247;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;glycosphingolipid biosynthetic process#GO:0006688;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000001456.1|UniProtKB=W5LZV9 W5LZV9 PTHR23343:SF117 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 1-LIKE binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198 biological regulation#GO:0065007;reproductive process#GO:0022414;fertilization#GO:0009566;regulation of reproductive process#GO:2000241;multicellular organismal process#GO:0032501;regulation of biological process#GO:0050789;cellular process#GO:0009987;negative regulation of biological process#GO:0048519;single fertilization#GO:0007338;cell-cell recognition#GO:0009988;binding of sperm to zona pellucida#GO:0007339;sexual reproduction#GO:0019953;cell activation#GO:0001775;cell recognition#GO:0008037;sperm-egg recognition#GO:0035036 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 LEPOC|Ensembl=ENSLOCG00000018349.1|UniProtKB=W5NP91 W5NP91 PTHR11711:SF139 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4A anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166 macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000011817.1|UniProtKB=W5N1M0 W5N1M0 PTHR11849:SF21 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-4 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>ELK#P01140;CCKR signaling map#P06959>SAP1#P07097;Interleukin signaling pathway#P00036>ELK#P00962 LEPOC|Ensembl=ENSLOCG00000003240.1|UniProtKB=W5M619 W5M619 PTHR14239:SF8 DUDULIN-RELATED METALLOREDUCTASE STEAP3 ferric-chelate reductase activity#GO:0000293;catalytic activity#GO:0003824;oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491 metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transition metal ion transport#GO:0000041;transport#GO:0006810 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000018073.1|UniProtKB=W5NNG5 W5NNG5 PTHR45134:SF5 OS08G0543275 PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015933.1|UniProtKB=W5NG57 W5NG57 PTHR14437:SF2 TRANSMEMBRANE PROTEIN 168 TRANSMEMBRANE PROTEIN 168 LEPOC|Ensembl=ENSLOCG00000008032.1|UniProtKB=W5MMZ9 W5MMZ9 PTHR48407:SF1 CRANIOFACIAL DEVELOPMENT PROTEIN 1 HETEROCHROMATIN-STABILIZING PROTEIN CFDP1 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 LEPOC|Ensembl=ENSLOCG00000011571.1|UniProtKB=W5NA02 W5NA02 H3Y2 PTHR45810:SF13 HISTONE H3.2 HISTONE H3 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014712.1|UniProtKB=W5NBV3 W5NBV3 PTHR15819:SF8 TRANSMEMBRANE PROTEIN FAM155 NALCN CHANNEL AUXILIARY FACTOR 2 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108 inorganic cation import across plasma membrane#GO:0098659;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012141.1|UniProtKB=W5N2S4 W5N2S4 PTHR45712:SF35 AGAP008170-PA PROLARGIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005933.1|UniProtKB=W5MFK3 W5MFK3 PTHR11388:SF100 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009233.1|UniProtKB=W5MSA0 W5MSA0 PTHR19305:SF1 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 47 binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905 secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;signaling#GO:0023052;export from cell#GO:0140352;exocytic process#GO:0140029;vesicle fusion to plasma membrane#GO:0099500;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;synaptic signaling#GO:0099536;endomembrane system organization#GO:0010256;neurotransmitter transport#GO:0006836;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;vesicle fusion#GO:0006906;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;membrane fusion#GO:0061025;synaptic vesicle membrane organization#GO:0048499;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;neurotransmitter secretion#GO:0007269 intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cytoplasm#GO:0005737;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 SNARE protein#PC00034;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004809.1|UniProtKB=W5MBL6 W5MBL6 PTHR12689:SF4 A1 CISTRON SPLICING FACTOR AAR2-RELATED PROTEIN AAR2 HOMOLOG RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000008938.1|UniProtKB=W5MR78 W5MR78 PTHR46755:SF5 METHIONINE-R-SULFOXIDE REDUCTASE B1 METHIONINE-R-SULFOXIDE REDUCTASE B1 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein repair#GO:0030091;primary metabolic process#GO:0044238;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000011509.1|UniProtKB=W5N0I2 W5N0I2 PTHR13464:SF0 TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP SAP30-BINDING PROTEIN membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000002782.1|UniProtKB=W5M4H8 W5M4H8 PTHR10082:SF3 INTEGRIN BETA SUBUNIT INTEGRIN BETA-LIKE PROTEIN 1 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell migration#GO:0016477;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;focal adhesion#GO:0005925;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;integrin complex#GO:0008305;anchoring junction#GO:0070161;signaling receptor complex#GO:0043235 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 LEPOC|Ensembl=ENSLOCG00000011307.1|UniProtKB=W5MZT3 W5MZT3 PTHR24150:SF8 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000010984.1|UniProtKB=W5MYL0 W5MYL0 PTHR15941:SF15 MYOZENIN MYOZENIN-3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;molecular condensate scaffold activity#GO:0140693 muscle cell development#GO:0055001;cellular response to stimulus#GO:0051716;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;skeletal muscle tissue development#GO:0007519;multicellular organismal process#GO:0032501;tissue development#GO:0009888;developmental process#GO:0032502;cellular developmental process#GO:0048869;system process#GO:0003008;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;actomyosin structure organization#GO:0031032;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular anatomical entity morphogenesis#GO:0032989;muscle organ development#GO:0007517;striated muscle tissue development#GO:0014706;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146 intracellular organelle#GO:0043229;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;I band#GO:0031674;membraneless organelle#GO:0043228;sarcomere#GO:0030017;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000016626.1|UniProtKB=W5NIT4 W5NIT4 PTHR48101:SF4 METHYLMALONYL-COA MUTASE, MITOCHONDRIAL-RELATED METHYLMALONYL-COA MUTASE, MITOCHONDRIAL small molecule binding#GO:0036094;catalytic activity#GO:0003824;binding#GO:0005488;intramolecular transferase activity#GO:0016866;heterocyclic compound binding#GO:1901363;isomerase activity#GO:0016853;tetrapyrrole binding#GO:0046906 nucleobase-containing compound metabolic process#GO:0006139;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;purine-containing compound catabolic process#GO:0072523;sulfur compound catabolic process#GO:0044273;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 isomerase#PC00135;metabolite interconversion enzyme#PC00262;mutase#PC00160 Methylmalonyl pathway#P02755>Methylmalonyl-CoA mutase#P03034;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA mutase#P03161 LEPOC|Ensembl=ENSLOCG00000016086.1|UniProtKB=W5NGR1 W5NGR1 PTHR21199:SF1 COMM DOMAIN-CONTAINING PROTEIN 1 COMM DOMAIN-CONTAINING PROTEIN 1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 positive regulation of protein metabolic process#GO:0051247;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;localization#GO:0051179;regulation of protein catabolic process#GO:0042176;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of protein ubiquitination#GO:0031396;transport#GO:0006810;establishment of localization#GO:0051234;regulation of catabolic process#GO:0009894;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;vesicle-mediated transport#GO:0016192;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000013205.1|UniProtKB=W5N6K4 W5N6K4 PTHR43437:SF3 HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000006310.1|UniProtKB=W5MGW0 W5MGW0 PTHR19139:SF34 AQUAPORIN TRANSPORTER AQUAPORIN-4 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;channel activity#GO:0015267 fluid transport#GO:0042044;establishment of localization#GO:0051234;water transport#GO:0006833;localization#GO:0051179;transport#GO:0006810 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003770.1|UniProtKB=W5M7Y7 W5M7Y7 PTHR20920:SF2 RPE-SPONDIN SOMATOMEDIN-B AND THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008561.1|UniProtKB=W5MPV1 W5MPV1 PTHR14392:SF3 NIBAN FAMILY MEMBER PROTEIN NIBAN 1 LEPOC|Ensembl=ENSLOCG00000004747.1|UniProtKB=W5MBD3 W5MBD3 PTHR32251:SF17 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE STEROID 5-ALPHA REDUCTASE C-TERMINAL DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004148.1|UniProtKB=W5M9A7 W5M9A7 PTHR19359:SF164 CYTOCHROME B5 CYTOCHROME B5 TYPE B tetrapyrrole binding#GO:0046906;binding#GO:0005488;heme binding#GO:0020037 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane#GO:0016020 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017982.1|UniProtKB=W5NN74 W5NN74 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 LEPOC|Ensembl=ENSLOCG00000003107.1|UniProtKB=W5M5Q3 W5M5Q3 PTHR12353:SF7 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 1 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cell junction#GO:0030054;organelle#GO:0043226;postsynaptic specialization#GO:0099572;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001165.1|UniProtKB=W5LYV8 W5LYV8 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006576.1|UniProtKB=W5MHT5 W5MHT5 PTHR45677:SF16 GLUTAMATE DECARBOXYLASE-RELATED CYSTEINE SULFINIC ACID DECARBOXYLASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;lyase activity#GO:0016829 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 LEPOC|Ensembl=ENSLOCG00000007005.1|UniProtKB=W5MJC2 W5MJC2 PTHR12442:SF12 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 4 protein binding#GO:0005515;binding#GO:0005488 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cilium movement#GO:0003341;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005932.1|UniProtKB=W5MFK7 W5MFK7 PTHR11475:SF38 OXIDASE/PEROXIDASE OXIDOREDUCTASE PXDNL-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000001822.1|UniProtKB=W5M147 W5M147 PTHR15601:SF14 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN 1 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008499.1|UniProtKB=W5MPP6 W5MPP6 PTHR21683:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 42 HOMOLOG ISOFORM X1 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005935.1|UniProtKB=W5MFK5 W5MFK5 PTHR14057:SF34 TRANSCRIPTION FACTOR ONECUT ONE CUT DOMAIN FAMILY MEMBER 3 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010734.1|UniProtKB=W5MXQ1 W5MXQ1 PTHR11254:SF340 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE APOPTOSIS-RESISTANT E3 UBIQUITIN PROTEIN LIGASE 1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004539.1|UniProtKB=W5MAM2 W5MAM2 PTHR13396:SF4 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY-INTERACTING PROTEIN 2 ubiquitin-dependent protein catabolic process#GO:0006511;regulation of protein modification process#GO:0031399;macromolecule metabolic process#GO:0043170;regulation of protein ubiquitination#GO:0031396;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;biological regulation#GO:0065007;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;protein metabolic process#GO:0019538;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of protein modification by small protein conjugation or removal#GO:1903320 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000014053.1|UniProtKB=W5N9L3 W5N9L3 PTHR24103:SF624 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF CONTAINING 54 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008557.1|UniProtKB=W5MPU8 W5MPU8 PTHR46643:SF2 HOMEOBOX PROTEIN GOOSECOID-RELATED HOMEOBOX PROTEIN GOOSECOID sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008752.1|UniProtKB=W5MQK3 W5MQK3 PTHR24416:SF130 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 2 catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;fibroblast growth factor binding#GO:0017134;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;angiogenesis#GO:0001525;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;blood vessel morphogenesis#GO:0048514;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;tube development#GO:0035295;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 LEPOC|Ensembl=ENSLOCG00000000149.1|UniProtKB=W5LVL0 W5LVL0 KATNAL1 PTHR23074:SF65 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 1 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017941.1|UniProtKB=W5NN35 W5NN35 PTHR24366:SF92 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT NEURONAL PROTEIN 2 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000018125.1|UniProtKB=W5NNL7 W5NNL7 PTHR13559:SF1 INTRACELLULAR TRAFFIC PROTEIN-RELATED PROTEIN FUZZY HOMOLOG cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 LEPOC|Ensembl=ENSLOCG00000000811.1|UniProtKB=W5LXP1 W5LXP1 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 antigen binding#GO:0003823;binding#GO:0005488 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012100.1|UniProtKB=W5N2M6 W5N2M6 PTHR14235:SF0 OSTEOCALCIN OSTEOCALCIN structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;developmental process#GO:0032502;osteoblast differentiation#GO:0001649;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;ossification#GO:0001503;cell differentiation#GO:0030154;cellular process#GO:0009987;bone development#GO:0060348 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014763.1|UniProtKB=W5NC18 W5NC18 PTHR12489:SF17 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 3 PROTEIN multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009074.1|UniProtKB=W5MRP7 W5MRP7 PTHR31363:SF0 TRAF3-INTERACTING PROTEIN 1 TRAF3-INTERACTING PROTEIN 1 cilium organization#GO:0044782;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;localization#GO:0051179;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;intraciliary transport#GO:0042073;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;regulation of cytoskeleton organization#GO:0051493;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705 ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intraciliary transport particle B#GO:0030992;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000008709.1|UniProtKB=W5MQE5 W5MQE5 PTHR10555:SF31 SORTING NEXIN SORTING NEXIN-2 small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 retromer complex#GO:0030904;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017364.1|UniProtKB=W5NLG0 W5NLG0 PTHR46048:SF10 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017252.1|UniProtKB=W5NL31 W5NL31 PTHR44889:SF3 INACTIVE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1 HYDROXYSTEROID DEHYDROGENASE LIKE 1 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000017743.1|UniProtKB=W5NMI8 W5NMI8 PTHR11006:SF73 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 6 histone modifying activity#GO:0140993;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015463.1|UniProtKB=W5NEH2 W5NEH2 PTHR10606:SF15 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatase activity#GO:0016791;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;sugar-phosphatase activity#GO:0050308 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793 transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121;carbohydrate phosphatase#PC00066 LEPOC|Ensembl=ENSLOCG00000015848.1|UniProtKB=W5NFV2 W5NFV2 PTHR15052:SF2 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR COMPLEX SUBUNIT GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 2 rDNA binding#GO:0000182;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;rRNA transcription#GO:0009303;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transcription factor TFIIIC complex#GO:0000127 LEPOC|Ensembl=ENSLOCG00000017942.1|UniProtKB=W5NN36 W5NN36 PTHR24368:SF211 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 1 head development#GO:0060322;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;brain development#GO:0007420;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609;system development#GO:0048731;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;cell adhesion#GO:0007155;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000004842.1|UniProtKB=W5MBQ6 W5MBQ6 PTHR24410:SF21 HL07962P-RELATED BTB DOMAIN-CONTAINING PROTEIN defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006863.1|UniProtKB=W5MIU6 W5MIU6 PTHR10201:SF30 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-9 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Plasminogen activating cascade#P00050>pro-MMP-9#P01259;CCKR signaling map#P06959>MMP9#G06994;CCKR signaling map#P06959>MMP9#G07288;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000015646.1|UniProtKB=W5NF61 W5NF61 PTHR10183:SF395 CALPAIN CALPAIN-2 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002056.1|UniProtKB=W5M1X6 W5M1X6 PTHR21469:SF4 EXOPHILIN-5 EXOPHILIN-5 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;transport#GO:0006810;establishment of localization#GO:0051234;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of secretion#GO:0051047;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;regulation of secretion by cell#GO:1903530;intracellular signal transduction#GO:0035556;regulation of exocytosis#GO:0017157 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000001806.1|UniProtKB=W5M137 W5M137 PTHR46886:SF1 INSULIN-LIKE GROWTH FACTOR II INSULIN-LIKE GROWTH FACTOR 2 intercellular signal molecule#PC00207;growth factor#PC00112 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896 LEPOC|Ensembl=ENSLOCG00000011702.1|UniProtKB=W5N178 W5N178 PTHR46451:SF1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002923.1|UniProtKB=W5M4X6 W5M4X6 PTHR10036:SF7 CD59 GLYCOPROTEIN LY6_PLAUR DOMAIN-CONTAINING PROTEIN 1 neurotransmitter receptor regulator activity#GO:0099602;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;signaling receptor inhibitor activity#GO:0030547;signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548;acetylcholine receptor inhibitor activity#GO:0030550 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;response to chemical#GO:0042221 LEPOC|Ensembl=ENSLOCG00000000533.1|UniProtKB=W5LWT3 W5LWT3 PTHR23105:SF101 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002202.1|UniProtKB=W5M2J5 W5M2J5 PTHR11733:SF114 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015514.1|UniProtKB=W5NEN6 W5NEN6 PTHR10909:SF378 ELECTRON TRANSPORT OXIDOREDUCTASE ACYL-COENZYME A OXIDASE-LIKE PROTEIN nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;lipid binding#GO:0008289;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;organic acid binding#GO:0043177;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014947.1|UniProtKB=W5NCP9 W5NCP9 PTHR45930:SF1 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A2 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;positive regulation of signal transduction#GO:0009967;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;tube development#GO:0035295;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of canonical Wnt signaling pathway#GO:0090263;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;circulatory system development#GO:0072359;central nervous system development#GO:0007417;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;angiogenesis#GO:0001525;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000806.1|UniProtKB=W5LXP0 W5LXP0 PTHR11506:SF30 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 3 establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594 late endosome membrane#GO:0031902;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007179.1|UniProtKB=W5MJX7 W5MJX7 PTHR46294:SF1 SEGMENTATION PROTEIN EVEN-SKIPPED HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000018151.1|UniProtKB=W5NNP3 W5NNP3 PTHR46048:SF12 HYDROXYCARBOXYLIC ACID RECEPTOR 2 G-PROTEIN COUPLED RECEPTOR 81 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018008.1|UniProtKB=W5NNA0 W5NNA0 PTHR10270:SF113 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-11 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;camera-type eye development#GO:0043010;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of metabolic process#GO:0019222;camera-type eye morphogenesis#GO:0048593;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;sensory organ morphogenesis#GO:0090596;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;eye development#GO:0001654;sensory system development#GO:0048880;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015607.1|UniProtKB=W5NF05 W5NF05 PTHR11705:SF94 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A1 catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000016413.1|UniProtKB=W5NI14 W5NI14 PTHR48041:SF113 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 5 lipid transfer activity#GO:0120013;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;cholesterol transfer activity#GO:0120020;sterol transfer activity#GO:0120015;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cholesterol homeostasis#GO:0042632;establishment of localization#GO:0051234;sterol transport#GO:0015918;transport#GO:0006810;chemical homeostasis#GO:0048878;lipid transport#GO:0006869;cholesterol efflux#GO:0033344;cellular process#GO:0009987;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;localization#GO:0051179;lipid localization#GO:0010876;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;membrane#GO:0016020;ATP-binding cassette (ABC) transporter complex#GO:0043190;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012479.1|UniProtKB=W5N412 W5N412 PTHR13414:SF9 HUEL-CATION TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A9, MITOCHONDRIAL cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;zinc ion transport#GO:0006829;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015709.1|UniProtKB=W5NFC9 W5NFC9 PTHR10906:SF10 SECY/SEC61-ALPHA FAMILY MEMBER PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 2 transmembrane protein transporter activity#GO:0008320;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein transmembrane transport#GO:0071806;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;post-translational protein targeting to membrane, translocation#GO:0031204;protein transport#GO:0015031;localization within membrane#GO:0051668 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;rough endoplasmic reticulum#GO:0005791;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009398.1|UniProtKB=W5MSV5 W5MSV5 PTHR23227:SF88 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002314.1|UniProtKB=W5M2V0 W5M2V0 PTHR20920:SF6 RPE-SPONDIN SOMATOMEDIN B AND THROMBOSPONDIN TYPE 1 DOMAIN CONTAINING LEPOC|Ensembl=ENSLOCG00000006205.1|UniProtKB=W5MGI7 W5MGI7 PTHR24073:SF1089 DRAB5-RELATED RAS-RELATED PROTEIN RAB-6A-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 establishment of protein localization#GO:0045184;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;protein localization to membrane#GO:0072657;cytosolic transport#GO:0016482;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000007878.1|UniProtKB=W5MMF3 W5MMF3 PTHR48225:SF7 HORMA DOMAIN-CONTAINING PROTEIN 1 MEIOSIS-SPECIFIC PROTEIN HOP1 negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;regulation of reproductive process#GO:2000241;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;negative regulation of cell cycle#GO:0045786;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cell cycle checkpoint signaling#GO:0000075;synaptonemal complex assembly#GO:0007130;cellular component assembly#GO:0022607;homologous chromosome pairing at meiosis#GO:0007129;regulation of cell cycle process#GO:0010564;nuclear division#GO:0000280;meiosis I#GO:0007127;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000005318.1|UniProtKB=W5MDE6 W5MDE6 PTHR35665:SF1 PROTEIN LKAAEAR1 PROTEIN LKAAEAR1 LEPOC|Ensembl=ENSLOCG00000014200.1|UniProtKB=W5NA35 W5NA35 PTHR11216:SF62 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle assembly#GO:0070925;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;protein localization to plasma membrane#GO:0072659;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;endocytosis#GO:0006897;endocytic recycling#GO:0032456;cell projection organization#GO:0030030;intracellular transport#GO:0046907;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;recycling endosome#GO:0055037;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003818.1|UniProtKB=W5M845 W5M845 PTHR17554:SF2 TYRO PROTEIN TYROSINE KINASE-BINDING PROTEIN TYRO PROTEIN TYROSINE KINASE-BINDING PROTEIN signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;regulation of immune effector process#GO:0002697;negative regulation of multicellular organismal process#GO:0051241;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;negative regulation of cell activation#GO:0050866;defense response#GO:0006952;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;negative regulation of cell population proliferation#GO:0008285;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of lymphocyte proliferation#GO:0050670;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of biosynthetic process#GO:0009890;positive regulation of immune effector process#GO:0002699;positive regulation of cell activation#GO:0050867;immune system process#GO:0002376;regulation of cell killing#GO:0031341;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of B cell proliferation#GO:0030888;leukocyte activation involved in immune response#GO:0002366;regulation of leukocyte proliferation#GO:0070663;positive regulation of immune system process#GO:0002684;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;inflammatory response#GO:0006954;cell activation#GO:0001775;regulation of leukocyte mediated cytotoxicity#GO:0001910;leukocyte activation#GO:0045321;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of leukocyte mediated immunity#GO:0002705;macrophage activation#GO:0042116;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular component organization#GO:0051130;cell activation involved in immune response#GO:0002263;regulation of leukocyte activation#GO:0002694;negative regulation of gene expression#GO:0010629;regulation of cell activation#GO:0050865;negative regulation of metabolic process#GO:0009892;regulation of lymphocyte activation#GO:0051249;positive regulation of leukocyte activation#GO:0002696;immune effector process#GO:0002252;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of B cell activation#GO:0050864;response to stress#GO:0006950;myeloid leukocyte activation#GO:0002274;regulation of multicellular organismal process#GO:0051239;microglial cell activation#GO:0001774 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014756.1|UniProtKB=W5NC14 W5NC14 PTHR46735:SF3 CALPAIN, SMALL SUBUNIT 1 A-RELATED CALPAIN SMALL SUBUNIT 1A-RELATED cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;caspase complex#GO:0008303;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000007573.1|UniProtKB=W5MLC9 W5MLC9 PTHR24388:SF60 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR SCRATCH 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000011291.1|UniProtKB=W5MZS2 W5MZS2 PTHR12650:SF30 40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI FAU UBIQUITIN-LIKE AND RIBOSOMAL PROTEIN S30 FUSION A-RELATED cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000001319.1|UniProtKB=W5LZH3 W5LZH3 PTHR10648:SF38 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;chromosome segregation#GO:0007059;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;meiotic sister chromatid cohesion#GO:0051177;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;sister chromatid cohesion#GO:0007062 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 LEPOC|Ensembl=ENSLOCG00000008723.1|UniProtKB=W5MQG4 W5MQG4 PTHR12450:SF28 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 FAM20C GOLGI ASSOCIATED SECRETORY PATHWAY KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012259.1|UniProtKB=W5N378 W5N378 PTHR15904:SF16 FAM13 PROTEIN FAM13B LEPOC|Ensembl=ENSLOCG00000002120.1|UniProtKB=W5M274 W5M274 PTHR45817:SF2 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 3 catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000004347.1|UniProtKB=W5M9Z8 W5M9Z8 PTHR22780:SF5 ADAPTIN, ALPHA/GAMMA/EPSILON AP-1 COMPLEX SUBUNIT GAMMA cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;Golgi to endosome transport#GO:0006895;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane coat#GO:0030117;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000394.1|UniProtKB=W5LWG4 W5LWG4 PTHR45831:SF3 LD24721P SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN ALPHA protein targeting to ER#GO:0045047;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000010527.1|UniProtKB=W5MWZ9 W5MWZ9 PTHR24356:SF224 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 4 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;signal transduction#GO:0007165;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005787.1|UniProtKB=W5MF27 W5MF27 PTHR24388:SF118 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 507 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000016370.1|UniProtKB=W5NHV3 W5NHV3 PTHR21648:SF0 FLAGELLAR RADIAL SPOKE PROTEIN 3 RADIAL SPOKE HEAD PROTEIN 3 HOMOLOG cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008712.1|UniProtKB=W5MQE3 W5MQE3 PTHR11636:SF125 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 3 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000014438.1|UniProtKB=W5NAW2 W5NAW2 PTHR24072:SF153 RHO FAMILY GTPASE TRANSFORMING PROTEIN RHOA binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;actomyosin structure organization#GO:0031032;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;actin filament bundle organization#GO:0061572;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;Rho protein signal transduction#GO:0007266;stress fiber assembly#GO:0043149;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;contractile actin filament bundle assembly#GO:0030038;cell migration#GO:0016477;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;actin filament bundle assembly#GO:0051017;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029 cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;dendritic spine#GO:0043197;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425;cell division site#GO:0032153;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;neuron projection#GO:0043005;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;cell junction#GO:0030054;cleavage furrow#GO:0032154 G-protein#PC00020;small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948;Ras Pathway#P04393>Rho#P04578;CCKR signaling map#P06959>RHOA-GDP#P07019;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Axon guidance mediated by semaphorins#P00007>Rho#P00341;CCKR signaling map#P06959>RHOA-GTP#P07188;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Angiogenesis#P00005>GTPase#P00254 LEPOC|Ensembl=ENSLOCG00000014276.1|UniProtKB=W5NAC1 W5NAC1 PTHR11346:SF32 GALECTIN GALECTIN-4 carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000015592.1|UniProtKB=W5NEZ0 W5NEZ0 PTHR24064:SF449 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 6-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;lipid localization#GO:0010876 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000011065.1|UniProtKB=W5MYX6 W5MYX6 PTHR23033:SF13 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011525.1|UniProtKB=W5N0K0 W5N0K0 PTHR14360:SF11 PROTEIN FMP32, MITOCHONDRIAL MITOCHONDRIAL CALCIUM UNIPORTER REGULATOR 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987 mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009453.1|UniProtKB=W5MT32 W5MT32 PTHR11216:SF54 EH DOMAIN EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;import into cell#GO:0098657;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117;plasma membrane#GO:0005886;cytoplasm#GO:0005737;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008294.1|UniProtKB=W5MNW7 W5MNW7 PTHR46518:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 151 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 3 microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cilium movement#GO:0003341;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000018164.1|UniProtKB=W5NNQ6 W5NNQ6 PTHR10489:SF730 CELL ADHESION MOLECULE CHEMOKINE XC RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930 cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000010191.1|UniProtKB=W5MVS0 W5MVS0 PTHR21014:SF5 PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE TYPE 2 PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 4-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839 vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;phagocytic vesicle#GO:0045335;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000006749.1|UniProtKB=W5MIF3 W5MIF3 PTHR13703:SF68 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular response to growth factor stimulus#GO:0071363;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;response to BMP#GO:0071772;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000009489.1|UniProtKB=W5MT87 W5MT87 PTHR14247:SF10 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 response to nitrogen compound#GO:1901698;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;positive regulation of signal transduction#GO:0009967;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;positive regulation of response to stimulus#GO:0048584;cellular response to nitrogen compound#GO:1901699;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of cellular process#GO:0048522;ERBB signaling pathway#GO:0038127;positive regulation of signaling#GO:0023056;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725 LEPOC|Ensembl=ENSLOCG00000001973.1|UniProtKB=W5M1M7 W5M1M7 PTHR15511:SF2 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012788.1|UniProtKB=W5N525 W5N525 PTHR10551:SF9 FASCIN FASCIN-2 actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 supramolecular fiber organization#GO:0097435;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;cell migration#GO:0016477;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000006151.1|UniProtKB=W5MGC2 W5MGC2 PTHR15380:SF2 CEROID-LIPOFUSCINOSIS, NEURONAL 5 BIS(MONOACYLGLYCERO)PHOSPHATE SYNTHASE CLN5 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824 vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;lysosome organization#GO:0007040;lytic vacuole organization#GO:0080171;organelle organization#GO:0006996;cellular component organization#GO:0016043 lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000015265.1|UniProtKB=W5NDS6 W5NDS6 PTHR11085:SF2 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NOVEL PROTEIN SIMILAR TO VERTEBRATE SIRTUIN (SILENT MATING TYPE INFORMATION REGULATION 2 HOMOLOG) 2 (S. CEREVISIAE) (SIRT2) histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;deacylase activity#GO:0160215;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;NAD-dependent protein lysine deacetylase activity#GO:0034979;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000006843.1|UniProtKB=W5MIS8 W5MIS8 PTHR11339:SF371 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-2 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000016363.1|UniProtKB=W5NHU5 W5NHU5 PTHR16087:SF0 TRANSMEMBRANE PROTEIN 206 PROTON-ACTIVATED CHLORIDE CHANNEL LEPOC|Ensembl=ENSLOCG00000017977.1|UniProtKB=W5NN69 W5NN69 PTHR19268:SF4 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 173-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008627.1|UniProtKB=W5MQ44 W5MQ44 PTHR12187:SF4 AGAP000124-PA INOSITOL POLYPHOSPHATE-4-PHOSPHATASE TYPE I A catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;regulation of intracellular signal transduction#GO:1902531;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cell junction#GO:0030054;postsynaptic density#GO:0014069;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic specialization#GO:0099572;membrane#GO:0016020;postsynapse#GO:0098794 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000003809.1|UniProtKB=W5M858 W5M858 PTHR15012:SF33 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;plasma membrane region#GO:0098590;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cell junction#GO:0030054;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical junction complex#GO:0043296;apical part of cell#GO:0045177 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000009567.1|UniProtKB=W5MTI2 W5MTI2 PTHR16514:SF4 LOW DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING 4A LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488 negative regulation of response to stimulus#GO:0048585;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;early endosome membrane#GO:0031901;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000017601.1|UniProtKB=W5NM47 W5NM47 PTHR24230:SF128 G-PROTEIN COUPLED RECEPTOR BLT1-LIKE1 PROTEIN-RELATED G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016890.1|UniProtKB=W5NJS1 W5NJS1 PTHR45910:SF1 N-ALPHA-ACETYLTRANSFERASE 20 N-ALPHA-ACETYLTRANSFERASE 20 acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000004041.1|UniProtKB=W5M8X8 W5M8X8 PTHR37457:SF4 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049 protein metabolic process#GO:0019538;translation#GO:0006412;regulation of cellular process#GO:0050794;protein biosynthetic process#GO:0160307;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;translational elongation#GO:0006414;metabolic process#GO:0008152;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000014757.1|UniProtKB=W5NC31 W5NC31 PTHR16166:SF125 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13C phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215 localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;lipid localization#GO:0010876;catabolic process#GO:0009056;cellular component organization#GO:0016043;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;transport#GO:0006810;lipid transport#GO:0006869;macroautophagy#GO:0016236;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;autophagy#GO:0006914 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;mitochondrion#GO:0005739;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011299.1|UniProtKB=W5MZS7 W5MZS7 PTHR24025:SF31 DESMOGLEIN FAMILY MEMBER NEURAL-CADHERIN ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000000215.1|UniProtKB=W5LVT1 W5LVT1 PTHR16675:SF237 MHC CLASS I-RELATED MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002721.1|UniProtKB=W5M489 W5M489 PTHR23354:SF131 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED MTOR-ASSOCIATED PROTEIN MEAK7 cell communication#GO:0007154;response to oxidative stress#GO:0006979;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;TOR signaling#GO:0031929;signaling#GO:0023052;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009663.1|UniProtKB=W5MTW8 W5MTW8 PTHR11679:SF2 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;SNARE binding#GO:0000149;syntaxin binding#GO:0019905;protein binding#GO:0005515 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000012894.1|UniProtKB=W5N5H1 W5N5H1 PTHR31017:SF1 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED LATE SECRETORY PATHWAY PROTEIN AVL9 HOMOLOG cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005690.1|UniProtKB=W5MER0 W5MER0 PTHR12763:SF7 FAMILY NOT NAMED DNAJ HOMOLOG SUBFAMILY C MEMBER 15 ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;protein transport#GO:0015031;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150 organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organelle envelope#GO:0031967;membrane protein complex#GO:0098796 LEPOC|Ensembl=ENSLOCG00000013396.1|UniProtKB=W5N7C1 W5N7C1 PTHR11920:SF458 GUANYLYL CYCLASE GUANYLATE CYCLASE molecular transducer activity#GO:0060089;lyase activity#GO:0016829;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975 ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanylate cyclase#PC00114;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000007897.1|UniProtKB=W5MMI1 W5MMI1 PTHR21456:SF3 FAMILY WITH SEQUENCE SIMILARITY 102 EEIG FAMILY MEMBER 2 LEPOC|Ensembl=ENSLOCG00000005357.1|UniProtKB=W5MDJ4 W5MDJ4 PTHR11728:SF32 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)], CYTOPLASMIC oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015517.1|UniProtKB=W5NEP0 W5NEP0 PTHR14113:SF6 PICCOLO/BASSOON PROTEIN PICCOLO structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 cell junction organization#GO:0034330;synapse assembly#GO:0007416;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;protein localization to cell junction#GO:1902414;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;cellular process#GO:0009987;protein localization to synapse#GO:0035418;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;intracellular protein localization#GO:0008104;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;axon#GO:0030424;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;GABA-ergic synapse#GO:0098982;cell projection#GO:0042995;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;presynaptic active zone#GO:0048786;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;glutamatergic synapse#GO:0098978;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;presynapse#GO:0098793;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000017361.1|UniProtKB=W5NLF7 W5NLF7 PTHR16277:SF10 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 SERTA DOMAIN-CONTAINING PROTEIN 2 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000007776.1|UniProtKB=W5MM36 W5MM36 PTHR32546:SF11 G-PROTEIN COUPLED RECEPTOR 158-RELATED METABOTROPIC GLYCINE RECEPTOR transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014624.1|UniProtKB=W5NBI8 W5NBI8 PTHR23257:SF755 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012296.1|UniProtKB=W5N3C1 W5N3C1 PTHR11486:SF21 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 10 molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083 regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;wound healing#GO:0042060;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;signaling#GO:0023052;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;positive chemotaxis#GO:0050918;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;taxis#GO:0042330;response to chemical#GO:0042221;nervous system development#GO:0007399;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;chemotaxis#GO:0006935;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;locomotion#GO:0040011;response to fibroblast growth factor#GO:0071774;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;response to wounding#GO:0009611;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012 extracellular region#GO:0005576;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000005559.1|UniProtKB=W5MEA8 W5MEA8 PTHR14494:SF0 ALADIN/ADRACALIN/AAAS ALADIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;mitotic spindle assembly#GO:0090307;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;spindle assembly#GO:0051225;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;nuclear division#GO:0000280 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000005858.1|UniProtKB=W5MFB4 W5MFB4 PTHR13847:SF187 SARCOSINE DEHYDROGENASE-RELATED DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000001106.1|UniProtKB=W5LYP0 W5LYP0 PTHR43580:SF10 OXIDOREDUCTASE GLYR1-RELATED CYTOKINE-LIKE NUCLEAR FACTOR N-PAC DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006660.1|UniProtKB=W5MI39 W5MI39 PTHR12127:SF6 MUCOLIPIN MUCOLIPIN-1 ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000003979.1|UniProtKB=W5M8P1 W5M8P1 PTHR14429:SF5 FIBROSIN FAMILY MEMBER AUTISM SUSCEPTIBILITY GENE 2 PROTEIN LEPOC|Ensembl=ENSLOCG00000002673.1|UniProtKB=W5M441 W5M441 PTHR22603:SF36 CHOLINE/ETHANOALAMINE KINASE CHOLINE KINASE ALPHA phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphatidylcholine biosynthetic process#GO:0006656;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine metabolic process#GO:0046470;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000015781.1|UniProtKB=W5NFM5 W5NFM5 PTHR38537:SF12 JITTERBUG, ISOFORM N FILAMIN-C LEPOC|Ensembl=ENSLOCG00000007836.1|UniProtKB=W5MMA4 W5MMA4 PTHR12847:SF16 ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED ADAPTIN EAR-BINDING COAT-ASSOCIATED PROTEIN 2 cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated vesicle#GO:0030136;clathrin vesicle coat#GO:0030125;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000013047.1|UniProtKB=W5N609 W5N609 PTHR14511:SF15 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G PROTEIN-COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER C molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047 membrane#GO:0016020;cell periphery#GO:0071944;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010504.1|UniProtKB=W5MWW4 W5MWW4 PTHR17614:SF12 ZINC FINGER-CONTAINING ZINC FINGER PROTEIN 804B intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008212.1|UniProtKB=W5MNL1 W5MNL1 PTHR12932:SF16 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 3 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;microtubule bundle formation#GO:0001578;positive regulation of cellular component organization#GO:0051130;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;positive regulation of protein polymerization#GO:0032273;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000005425.1|UniProtKB=W5MDT7 W5MDT7 PTHR13316:SF0 ZINC FINGER, CCHC DOMAIN CONTAINING 8 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011216.1|UniProtKB=W5MZG7 W5MZG7 PTHR11046:SF31 OLIGORIBONUCLEASE, MITOCHONDRIAL THAP9-LIKE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN RNA metabolism protein#PC00031;endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000006553.1|UniProtKB=W5MHQ9 W5MHQ9 PTHR23058:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX14 PEROXISOMAL MEMBRANE PROTEIN PEX14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 peroxisome organization#GO:0007031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;peroxisomal transport#GO:0043574;protein transport#GO:0015031;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisomal membrane#GO:0005778;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transporter complex#GO:1990351;intracellular organelle#GO:0043229 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000007140.1|UniProtKB=W5MJT5 W5MJT5 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012941.1|UniProtKB=W5N5M6 W5N5M6 PTHR10388:SF51 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR 1B translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000015742.1|UniProtKB=W5NFG9 W5NFG9 PTHR21683:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED CILIA AND FLAGELLA ASSOCIATED PROTEIN 100 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000006942.1|UniProtKB=W5MJ40 W5MJ40 PTHR10913:SF6 FOLLISTATIN-RELATED FOLLISTATIN protein-containing complex binding#GO:0044877;binding#GO:0005488;activin binding#GO:0048185 cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#G06671;Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#P06835;Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#G06885 LEPOC|Ensembl=ENSLOCG00000016273.1|UniProtKB=W5NHG4 W5NHG4 PTHR24123:SF140 ANKYRIN REPEAT-CONTAINING ZU5 DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016765.1|UniProtKB=W5NJB4 W5NJB4 PTHR10807:SF56 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 9 phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;protein phosphatase binding#GO:0019903 phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;lipid modification#GO:0030258;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol dephosphorylation#GO:0046856;negative regulation of catabolic process#GO:0009895;dephosphorylation#GO:0016311;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;negative regulation of metabolic process#GO:0009892;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794 membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000009817.1|UniProtKB=W5MUE7 W5MUE7 PTHR22731:SF3 RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1 RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1 hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;ribonuclease P activity#GO:0004526;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;tRNA metabolic process#GO:0006399;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774 nucleolar ribonuclease P complex#GO:0005655;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;multimeric ribonuclease P complex#GO:0030681;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;ribonuclease P complex#GO:0030677;endoribonuclease complex#GO:1902555;intracellular membraneless organelle#GO:0043232;ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;endonuclease complex#GO:1905348 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004542.1|UniProtKB=W5MAM3 W5MAM3 PTHR24232:SF114 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 55-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000635.1|UniProtKB=W5LX45 W5LX45 PTHR12210:SF187 DULLARD PROTEIN PHOSPHATASE CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 2 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000011858.1|UniProtKB=W5N1S3 W5N1S3 PTHR12019:SF22 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN LEM DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000004959.1|UniProtKB=W5MC74 W5MC74 PTHR23220:SF90 INTEGRIN ALPHA INTEGRIN ALPHA-7 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell migration#GO:0016477;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;leukocyte migration#GO:0050900;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;immune system process#GO:0002376;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000013724.1|UniProtKB=W5N8G5 W5N8G5 PTHR34441:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000007172.1|UniProtKB=W5MJY6 W5MJY6 PTHR24115:SF513 KINESIN-RELATED KINESIN-1 HEAVY CHAIN ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657 microtubule-based transport#GO:0099111;organelle localization#GO:0051640;axonal transport#GO:0098930;anterograde axonal transport#GO:0008089;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;synaptic vesicle transport#GO:0048489;axo-dendritic transport#GO:0008088;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;cytoskeleton-dependent intracellular transport#GO:0030705 microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000000059.1|UniProtKB=W5LVB2 W5LVB2 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014483.1|UniProtKB=W5NB15 W5NB15 PTHR10015:SF336 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK TRANSCRIPTION FACTOR, Y-LINKED helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000011512.1|UniProtKB=W5N0I9 W5N0I9 PTHR13723:SF158 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 3 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000002250.1|UniProtKB=W5M2L3 W5M2L3 PTHR23328:SF2 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF169 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;chromatin binding#GO:0003682;acyltransferase activity#GO:0016746;binding#GO:0005488;nucleosome binding#GO:0031491;ubiquitin-protein transferase activity#GO:0004842;protein-containing complex binding#GO:0044877 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;site of double-strand break#GO:0035861;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000007848.1|UniProtKB=W5MMC9 W5MMC9 PTHR10997:SF7 IMPORTIN-7, 8, 11 IMPORTIN-11 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003660.1|UniProtKB=W5M7I9 W5M7I9 PTHR10026:SF42 CYCLIN CYCLIN-T1 protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase activator activity#GO:0030295;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription elongation#GO:0032784;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000001335.1|UniProtKB=W5LZF8 W5LZF8 DOHH PTHR12697:SF42 PBS LYASE HEAT-LIKE PROTEIN DEOXYHYPUSINE HYDROXYLASE oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000008004.1|UniProtKB=W5MMW1 W5MMW1 PTHR11639:SF131 S100 CALCIUM-BINDING PROTEIN PROTEIN S100 small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000002240.1|UniProtKB=W5M2K1 W5M2K1 PTHR28589:SF1 28S RIBOSOMAL PROTEIN S34, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS34 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000003984.1|UniProtKB=W5M8P8 W5M8P8 PTHR24393:SF60 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 16 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000007036.1|UniProtKB=W5MJG9 W5MJG9 PTHR11616:SF336 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NORADRENALINE TRANSPORTER solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 organic hydroxy compound transport#GO:0015850;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;cellular localization#GO:0051641;trans-synaptic signaling#GO:0099537;metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;import into cell#GO:0098657;amino acid transport#GO:0006865;transport#GO:0006810;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;neurotransmitter transport#GO:0006836;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic transmission, dopaminergic#GO:0001963;nitrogen compound transport#GO:0071705;synaptic signaling#GO:0099536 axon#GO:0030424;cell body#GO:0044297;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;presynapse#GO:0098793;neuron projection#GO:0043005;membrane#GO:0016020;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane region#GO:0098590 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>NET#P00064 LEPOC|Ensembl=ENSLOCG00000004802.1|UniProtKB=W5MBK6 W5MBK6 PTHR19282:SF25 TETRASPANIN UROPLAKIN-1A cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001196.1|UniProtKB=W5LYY8 W5LYY8 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 binding#GO:0005488;antigen binding#GO:0003823 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015643.1|UniProtKB=W5NF48 W5NF48 PTHR12563:SF15 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 2, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerophospholipid metabolic process#GO:0006650;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013017.1|UniProtKB=W5N5X7 W5N5X7 PTHR17613:SF23 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN FAMILY 1B cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000018248.1|UniProtKB=W5NNZ0 W5NNZ0 PTHR28615:SF1 PAK4-INHIBITOR INKA1-RELATED PAK4-INHIBITOR INKA1 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase inhibitor activity#GO:0019210 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011374.1|UniProtKB=W5N018 W5N018 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003847.1|UniProtKB=W5M887 W5M887 PTHR11588:SF4 TUBULIN TUBULIN DELTA CHAIN ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639 mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874 cytoskeletal protein#PC00085;tubulin#PC00228 LEPOC|Ensembl=ENSLOCG00000002492.1|UniProtKB=W5M3G7 W5M3G7 PTHR45989:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT GAMMA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;translation initiation factor activity#GO:0003743;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085;translation factor activity#GO:0180051 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000016054.1|UniProtKB=W5NGM1 W5NGM1 PTHR48092:SF10 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN-RELATED RECEPTOR GAMMA sequence-specific double-stranded DNA binding#GO:1990837;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000013032.1|UniProtKB=W5N5Z2 W5N5Z2 PTHR33766:SF1 PROTEIN FAM181B PROTEIN FAM181A LEPOC|Ensembl=ENSLOCG00000018267.1|UniProtKB=W5NP09 W5NP09 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017967.1|UniProtKB=W5NN61 W5NN61 PTHR13864:SF15 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 HOMOLOG-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000009075.1|UniProtKB=W5MRP6 W5MRP6 PTHR11987:SF48 ALPHA-2,8-SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-POLY-ALPHA-2,8-SIALYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373 oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015395.1|UniProtKB=W5NE84 W5NE84 PTHR43429:SF2 PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING TRNA LIGASE COMPLEX-ASSOCIATED NAD(P)H DEHYDROGENASE PYROXD1 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009973.1|UniProtKB=W5MUY6 W5MUY6 PTHR19957:SF104 SYNTAXIN SYNTAXIN-6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;vesicle fusion#GO:0006906;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284 cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;SNARE complex#GO:0031201;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 SNARE protein#PC00034 Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074 LEPOC|Ensembl=ENSLOCG00000015217.1|UniProtKB=W5NDM0 W5NDM0 PTHR11480:SF104 SAPOSIN-RELATED SAPOSIN B-TYPE DOMAIN-CONTAINING PROTEIN primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011658.1|UniProtKB=W5N116 W5N116 PTHR11360:SF26 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 3 transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;monocarboxylic acid transmembrane transporter activity#GO:0008028 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009803.1|UniProtKB=W5MUC2 W5MUC2 PTHR31882:SF15 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 1 negative regulation of biological process#GO:0048519;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;biological process involved in interspecies interaction between organisms#GO:0044419;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;negative regulation of signal transduction#GO:0009968;response to lipopolysaccharide#GO:0032496;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;response to bacterium#GO:0009617;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to other organism#GO:0051707;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468 LEPOC|Ensembl=ENSLOCG00000015927.1|UniProtKB=W5NG52 W5NG52 PTHR45627:SF30 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 3 lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975 organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cyclic purine nucleotide metabolic process#GO:0052652;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;ribose phosphate biosynthetic process#GO:0046390 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 LEPOC|Ensembl=ENSLOCG00000008544.1|UniProtKB=W5MPT7 W5MPT7 PTHR14950:SF82 DICER-RELATED ENDORIBONUCLEASE DICER hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity, acting on DNA#GO:0140097;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cell death#GO:0008219;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;apoptotic DNA fragmentation#GO:0006309;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;siRNA processing#GO:0030422;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;DNA catabolic process#GO:0006308 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000009894.1|UniProtKB=W5MUQ2 W5MUQ2 PTHR10814:SF31 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 4 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 LEPOC|Ensembl=ENSLOCG00000001314.1|UniProtKB=W5LZE1 W5LZE1 PTHR10786:SF0 CHOLECYSTOKININ CHOLECYSTOKININ neuropeptide hormone activity#GO:0005184;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 digestion#GO:0007586;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;neuron projection#GO:0043005;extracellular region#GO:0005576 CCKR signaling map#P06959>CCK-G#P07062;CCKR signaling map#P06959>CCK-GRR#P07131;CCKR signaling map#P06959>CCK#P07077;CCKR signaling map#P06959>CCK-33#P07045;CCKR signaling map#P06959>CCK-22#P07022;CCKR signaling map#P06959>Pro CCK @ TGN#P07174;CCKR signaling map#P06959>CCK-83#P07118;CCKR signaling map#P06959>CCK-8#P07226;CCKR signaling map#P06959>Signal-pre-pro CCK#P07223;CCKR signaling map#P06959>Pre-pro CCK @ ER#P07128;CCKR signaling map#P06959>Pro-CCK @ secretory granule#P07206;CCKR signaling map#P06959>CCK-58#P07164 LEPOC|Ensembl=ENSLOCG00000003482.1|UniProtKB=W5M6X0 W5M6X0 PTHR22923:SF50 CEREBELLIN-RELATED CEREBELLIN-2 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013601.1|UniProtKB=W5N812 W5N812 PTHR10887:SF341 DNA2/NAM7 HELICASE FAMILY NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulatory ncRNA-mediated heterochromatin formation#GO:0031048;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000003313.1|UniProtKB=W5M6C6 W5M6C6 PTHR45704:SF2 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE LEPOC|Ensembl=ENSLOCG00000004320.1|UniProtKB=W5M9U9 W5M9U9 PTHR45879:SF1 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;intracellular signaling cassette#GO:0141124;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Apoptosis signaling pathway#P00006>ATF#P00302;p38 MAPK pathway#P05918>CREB#P06027;Enkephalin release#P05913>CREB#P05971;Gonadotropin-releasing hormone receptor pathway#P06664>CREB#P06749;CCKR signaling map#P06959>CREB1#P07232;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 LEPOC|Ensembl=ENSLOCG00000010693.1|UniProtKB=W5MXJ3 W5MXJ3 PTHR24060:SF147 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Ionotropic glutamate receptor pathway#P00037>mGluR 2/3#P01014;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Metabotropic glutamate receptor group II pathway#P00040>mGluR2/3#P01048 LEPOC|Ensembl=ENSLOCG00000017356.1|UniProtKB=W5NLF2 W5NLF2 PTHR14520:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 63 LARGE RIBOSOMAL SUBUNIT PROTEIN ML63 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014211.1|UniProtKB=W5NA45 W5NA45 PTHR33663:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 177 COILED-COIL DOMAIN-CONTAINING PROTEIN 177 LEPOC|Ensembl=ENSLOCG00000017560.1|UniProtKB=W5NM06 W5NM06 PTHR24232:SF108 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 35-LIKE-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005846.1|UniProtKB=W5MFC2 W5MFC2 PTHR45860:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT ALPHA translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000004887.1|UniProtKB=W5MBW4 W5MBW4 PTHR24388:SF42 ZINC FINGER PROTEIN ZINC FINGER PROTEIN SNAI2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007831.1|UniProtKB=W5MM97 W5MM97 PTHR23233:SF46 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 3 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006722.1|UniProtKB=W5MID2 W5MID2 PTHR45622:SF78 UBIQUITIN-PROTEIN LIGASE E3A-RELATED SECRETION-REGULATING GUANINE NUCLEOTIDE EXCHANGE FACTOR ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of protein secretion#GO:0050708;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of secretion#GO:0051046;regulation of establishment of protein localization#GO:0070201;post-translational protein modification#GO:0043687;negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cellular process#GO:0048523;regulation of protein transport#GO:0051223;negative regulation of biological process#GO:0048519;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of secretion by cell#GO:1903530;regulation of protein localization#GO:0032880;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein ubiquitination#GO:0016567;cellular process#GO:0009987;regulation of localization#GO:0032879;regulation of transport#GO:0051049;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007983.1|UniProtKB=W5MMT3 W5MMT3 PTHR13874:SF10 ENDOTHELIN ENDOTHELIN-1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;neuropeptide receptor binding#GO:0071855;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;regulation of blood pressure#GO:0008217;monoatomic ion homeostasis#GO:0050801;regulation of systemic arterial blood pressure#GO:0003073;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;system process#GO:0003008;regulation of smooth muscle contraction#GO:0006940;cellular homeostasis#GO:0019725;muscle contraction#GO:0006936;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;homeostatic process#GO:0042592;regulation of biological process#GO:0050789;muscle system process#GO:0003012;positive regulation of multicellular organismal process#GO:0051240;intracellular monoatomic ion homeostasis#GO:0006873;regulation of muscle system process#GO:0090257;regulation of biological quality#GO:0065008;inorganic ion homeostasis#GO:0098771;regulation of muscle contraction#GO:0006937;circulatory system process#GO:0003013;calcium ion homeostasis#GO:0055074 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Endothelin signaling pathway#P00019>Pre-pro ET1-4#P00576;Endothelin signaling pathway#P00019>Big ET1-4#P00574;Endothelin signaling pathway#P00019>Pro ET1-4#P00571;Endothelin signaling pathway#P00019>ET1-4#P00588 LEPOC|Ensembl=ENSLOCG00000007877.1|UniProtKB=W5MMF5 W5MMF5 PTHR12375:SF31 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN LUC7-LIKE 1-RELATED mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681 LEPOC|Ensembl=ENSLOCG00000015949.1|UniProtKB=W5NG82 W5NG82 PTHR21231:SF8 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein-binding activity modulator#PC00095;G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000000922.1|UniProtKB=W5LY22 W5LY22 PTHR11767:SF17 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 3 voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094 transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724 LEPOC|Ensembl=ENSLOCG00000011339.1|UniProtKB=W5MZX4 W5MZX4 PTHR13681:SF27 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL MOTOR NEURON PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 neuron development#GO:0048666;axonogenesis#GO:0007409;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;ribonucleoprotein complex biogenesis#GO:0022613;cell development#GO:0048468;mRNA metabolic process#GO:0016071;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cell projection morphogenesis#GO:0048858;protein-RNA complex organization#GO:0071826;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;RNA splicing#GO:0008380;neuron differentiation#GO:0030182;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;neuron projection development#GO:0031175;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;system development#GO:0048731;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;anatomical structure development#GO:0048856;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;multicellular organismal process#GO:0032501;macromolecule biosynthetic process#GO:0009059;axon development#GO:0061564 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;SMN complex#GO:0032797;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000012510.1|UniProtKB=W5N447 W5N447 PTHR13976:SF60 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000005802.1|UniProtKB=W5MF50 W5MF50 PTHR47977:SF8 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-34 carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;ion binding#GO:0043167;GTPase activity#GO:0003924;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787 establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;phagocytosis#GO:0006909;lytic vacuole organization#GO:0080171;transport#GO:0006810;membrane organization#GO:0061024;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;Golgi to plasma membrane transport#GO:0006893;vesicle fusion#GO:0006906;protein localization to plasma membrane#GO:0072659;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;phagolysosome assembly#GO:0001845;protein localization to cell periphery#GO:1990778;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;lysosome organization#GO:0007040;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;endocytosis#GO:0006897;Golgi to plasma membrane protein transport#GO:0043001;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657 Golgi cisterna#GO:0031985;phagocytic vesicle#GO:0045335;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;Golgi apparatus#GO:0005794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;Golgi stack#GO:0005795;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000013711.1|UniProtKB=W5N8E8 W5N8E8 PTHR11761:SF8 50S/60S RIBOSOMAL PROTEIN L14/L23 LARGE RIBOSOMAL SUBUNIT PROTEIN UL14 rRNA binding#GO:0019843;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017136.1|UniProtKB=W5NKL9 W5NKL9 PTHR15950:SF17 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 2 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007631.1|UniProtKB=W5MLJ6 W5MLJ6 PTHR23097:SF90 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11B transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008304.1|UniProtKB=W5MNZ4 W5MNZ4 PTHR11675:SF58 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 6 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015723.1|UniProtKB=W5NFE8 W5NFE8 PTHR21308:SF1 PHYTANOYL-COA ALPHA-HYDROXYLASE PHYTANOYL-COA DIOXYGENASE, PEROXISOMAL catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000952.1|UniProtKB=W5LY51 W5LY51 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017435.1|UniProtKB=W5NLN1 W5NLN1 PTHR12002:SF174 CLAUDIN CLAUDIN cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;paracellular transport#GO:0160184;establishment of localization#GO:0051234;cell-cell junction organization#GO:0045216;transport#GO:0006810;cell-cell junction assembly#GO:0007043 anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;apical junction complex#GO:0043296;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000004068.1|UniProtKB=W5M913 W5M913 PTHR22803:SF184 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED C-TYPE MANNOSE RECEPTOR 2 ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000013276.1|UniProtKB=W5N6U8 W5N6U8 PTHR13194:SF18 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010421.1|UniProtKB=W5MWN7 W5MWN7 PTHR10170:SF10 HUNTINGTON DISEASE PROTEIN HUNTINGTIN regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;regulation of signaling#GO:0023051;cellular localization#GO:0051641;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;central nervous system development#GO:0007417;establishment of organelle localization#GO:0051656;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;organelle localization#GO:0051640;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;transport#GO:0006810;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;vesicle cytoskeletal trafficking#GO:0099518;neurogenesis#GO:0022008;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 neuron projection#GO:0043005;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;axon#GO:0030424;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 Huntington disease#P00029>Htt#P00766;Huntington disease#P00029>PolyQ Htt#P00800;Huntington disease#P00029>PolyQ HTT#G01532;Huntington disease#P00029>Truncated Htt#P00761;Huntington disease#P00029>HTT#G01530 LEPOC|Ensembl=ENSLOCG00000014739.1|UniProtKB=W5NBY9 W5NBY9 PTHR23189:SF15 RNA RECOGNITION MOTIF-CONTAINING NON-POU DOMAIN-CONTAINING OCTAMER-BINDING PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017818.1|UniProtKB=W5NMR3 W5NMR3 PTHR10339:SF32 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 5-RELATED pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000010363.1|UniProtKB=W5MWE3 W5MWE3 PTHR46251:SF1 RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3 RUN DOMAIN-CONTAINING PROTEIN 3B LEPOC|Ensembl=ENSLOCG00000006808.1|UniProtKB=W5MIL4 W5MIL4 PTHR11847:SF4 RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN EL15 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008984.1|UniProtKB=W5MRE9 W5MRE9 PTHR24103:SF611 E3 UBIQUITIN-PROTEIN LIGASE TRIM BBOX AND DUF4200 DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015939.1|UniProtKB=W5NG73 W5NG73 SPAST PTHR23074:SF173 AAA DOMAIN-CONTAINING SPASTIN ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;neuron projection morphogenesis#GO:0048812;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cytoskeleton organization#GO:0007010;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039 intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000000912.1|UniProtKB=W5LY10 W5LY10 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 antigen binding#GO:0003823;binding#GO:0005488 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013453.1|UniProtKB=W5N7H5 W5N7H5 PTHR45970:SF5 AGAP004664-PA HOMEOBOX PROTEIN HOX-B9 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anterior/posterior pattern specification#GO:0009952;embryo development#GO:0009790;skeletal system development#GO:0001501;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;skeletal system morphogenesis#GO:0048705;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010227.1|UniProtKB=W5MVW3 W5MVW3 PTHR42693:SF5 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE D hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014206.1|UniProtKB=W5NA47 W5NA47 PTHR42776:SF16 SERINE PEPTIDASE S9 FAMILY MEMBER ACYLAMINO-ACID-RELEASING ENZYME-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003417.1|UniProtKB=W5M6P8 W5M6P8 PTHR10751:SF105 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 3 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000002947.1|UniProtKB=W5M515 W5M515 PTHR10117:SF8 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 3 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;single fertilization#GO:0007338;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;homeostatic process#GO:0042592;metal ion transport#GO:0030001;fertilization#GO:0009566;reproductive process#GO:0022414;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;sexual reproduction#GO:0019953;inorganic ion homeostasis#GO:0098771 cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000008854.1|UniProtKB=W5MQW0 W5MQW0 PTHR13156:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;organelle membrane#GO:0031090;oxidoreductase complex#GO:1990204;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002541.1|UniProtKB=W5M3M6 W5M3M6 PTHR12312:SF16 TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of BMP signaling pathway#GO:0030510;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 SCW signaling pathway#P06216>TSG#P06330;DPP-SCW signaling pathway#P06212>TSG#P06258;BMP/activin signaling pathway-drosophila#P06211>TSG#P06242;DPP signaling pathway#P06213>TSG#P06287 LEPOC|Ensembl=ENSLOCG00000007136.1|UniProtKB=W5MJT0 W5MJT0 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139 LEPOC|Ensembl=ENSLOCG00000007275.1|UniProtKB=W5MKA1 W5MKA1 PTHR14247:SF11 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 3A LEPOC|Ensembl=ENSLOCG00000003362.1|UniProtKB=W5M6H2 W5M6H2 PTHR10196:SF67 SUGAR KINASE SEDOHEPTULOKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;response to other organism#GO:0051707;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;generation of precursor metabolites and energy#GO:0006091;glucose 6-phosphate metabolic process#GO:0051156;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;primary metabolic process#GO:0044238;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;response to bacterium#GO:0009617;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;regulation of multicellular organismal process#GO:0051239;response to biotic stimulus#GO:0009607;NADP+ metabolic process#GO:0006739;cellular response to lipopolysaccharide#GO:0071222;regulation of macrophage activation#GO:0043030;cellular response to oxygen-containing compound#GO:1901701;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;nucleobase-containing small molecule metabolic process#GO:0055086;response to lipopolysaccharide#GO:0032496;metabolic process#GO:0008152;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of leukocyte activation#GO:0002694;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;response to molecule of bacterial origin#GO:0002237;regulation of cell activation#GO:0050865;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;cellular response to chemical stimulus#GO:0070887;glyceraldehyde-3-phosphate metabolic process#GO:0019682;response to oxygen-containing compound#GO:1901700 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137;carbohydrate kinase#PC00065 LEPOC|Ensembl=ENSLOCG00000003244.1|UniProtKB=W5M624 W5M624 PTHR13512:SF2 MEDIATOR COMPLEX SUBUNIT 28 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 28 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000004018.1|UniProtKB=W5M8T8 W5M8T8 PTHR12757:SF6 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 1 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012012.1|UniProtKB=W5N2B8 W5N2B8 PTHR43763:SF6 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 1 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004169.1|UniProtKB=W5M9D4 W5M9D4 PTHR18934:SF91 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16 binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000006998.1|UniProtKB=W5MJC4 W5MJC4 PTHR46025:SF2 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE 1 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-xylosyltransferase activity#GO:0035252;xylosyltransferase activity#GO:0042285;pentosyltransferase activity#GO:0016763 primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007947.1|UniProtKB=W5MMP2 W5MMP2 PTHR11387:SF2 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B1 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000006124.1|UniProtKB=W5MGC1 W5MGC1 PTHR46697:SF1 FORMIN-BINDING PROTEIN 4 FORMIN-BINDING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000008401.1|UniProtKB=W5MPB8 W5MPB8 PTHR13375:SF3 FMS INTERACTING PROTEIN THO COMPLEX SUBUNIT 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;gene expression#GO:0010467;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transcription export complex#GO:0000346;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000017944.1|UniProtKB=W5NN38 W5NN38 PTHR11984:SF106 CONNEXIN GAP JUNCTION PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 cell communication#GO:0007154;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;regulation of biological process#GO:0050789 membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell junction#GO:0030054;anchoring junction#GO:0070161 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000005105.1|UniProtKB=W5MCN6 W5MCN6 PTHR45787:SF5 LD11652P LIM DOMAIN TRANSCRIPTION FACTOR LMO4 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell fate specification#GO:0001708;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;neuron fate commitment#GO:0048663;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000016832.1|UniProtKB=W5NJL7 W5NJL7 PTHR13817:SF22 TITIN MYOMESIN-2 structural molecule activity#GO:0005198 actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle cell development#GO:0055001;cell development#GO:0048468;actomyosin structure organization#GO:0031032;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular organelle#GO:0043229;M band#GO:0031430;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;contractile muscle fiber#GO:0043292;A band#GO:0031672 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000017709.1|UniProtKB=W5NMF5 W5NMF5 PTHR24247:SF209 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M5 G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;acetylcholine receptor activity#GO:0015464;molecular transducer activity#GO:0060089 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 dendritic tree#GO:0097447;dendrite#GO:0030425;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;synapse#GO:0045202 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000013314.1|UniProtKB=W5N6Z8 W5N6Z8 PTHR12757:SF5 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 3 lipid transfer activity#GO:0120013;phosphatidylinositol transfer activity#GO:0008526;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215 establishment of localization#GO:0051234;transport#GO:0006810;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;phospholipid transport#GO:0015914;biological regulation#GO:0065007;lipid transport#GO:0006869;macromolecule localization#GO:0033036;localization#GO:0051179;regulation of signaling#GO:0023051;lipid localization#GO:0010876;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;organophosphate ester transport#GO:0015748;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016775.1|UniProtKB=W5NJC4 W5NJC4 PTHR33967:SF1 RAGULATOR COMPLEX PROTEIN LAMTOR4 RAGULATOR COMPLEX PROTEIN LAMTOR4 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 membrane protein complex#GO:0098796;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000003874.1|UniProtKB=W5M8B1 W5M8B1 PTHR21443:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular localization#GO:0051641;protein localization to Golgi apparatus#GO:0034067;endomembrane system organization#GO:0010256;protein localization to organelle#GO:0033365;Golgi organization#GO:0007030;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component organization#GO:0016043 COG complex#GO:0017119;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000005573.1|UniProtKB=W5MEC4 W5MEC4 PTHR10110:SF59 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 1 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078 homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009336.1|UniProtKB=W5MSP5 W5MSP5 PTHR24023:SF1132 COLLAGEN ALPHA COLLAGEN ALPHA-1(XVIII) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000017840.1|UniProtKB=W5NMT4 W5NMT4 PTHR11309:SF31 FRIZZLED FRIZZLED-7 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;non-canonical Wnt signaling pathway#GO:0035567;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428 LEPOC|Ensembl=ENSLOCG00000009739.1|UniProtKB=W5MU39 W5MU39 PTHR46024:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS HISTONE-LYSINE N-METHYLTRANSFERASE SETDB2 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 heterochromatin organization#GO:0070828;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000008958.1|UniProtKB=W5MRB0 W5MRB0 PTHR13943:SF37 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 1 A2-type glycerophospholipase activity#GO:0004623;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;carboxylic ester hydrolase activity#GO:0052689 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000016153.1|UniProtKB=W5NGZ6 W5NGZ6 PTHR45865:SF2 E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE SHPRH ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;response to stimulus#GO:0050896 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004504.1|UniProtKB=W5MAH5 W5MAH5 PTHR24085:SF1 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4IMMUNITYGROUP A MEMBER 1 nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;nuclear receptor binding#GO:0016922;sequence-specific DNA binding#GO:0043565 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;regulation of primary metabolic process#GO:0080090;response to peptide hormone#GO:0043434;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C4 zinc finger nuclear receptor#PC00169 CCKR signaling map#P06959>NR4A1#G07289;Gonadotropin-releasing hormone receptor pathway#P06664>Nur77#P06713;Gonadotropin-releasing hormone receptor pathway#P06664>Nur77#G06679;Gonadotropin-releasing hormone receptor pathway#P06664>Nur77#G06893;CCKR signaling map#P06959>NR4A1#G06995 LEPOC|Ensembl=ENSLOCG00000006813.1|UniProtKB=W5MIL9 W5MIL9 PTHR24253:SF197 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013603.1|UniProtKB=W5N820 W5N820 PTHR18945:SF455 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-3 channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810 postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic specialization#GO:0099572;organelle#GO:0043226;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;synaptic membrane#GO:0097060;cell junction#GO:0030054 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000008534.1|UniProtKB=W5MPR9 W5MPR9 PTHR35442:SF1 TRANSMEMBRANE PROTEIN 249 CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT THETA LEPOC|Ensembl=ENSLOCG00000017229.1|UniProtKB=W5NL01 W5NL01 PTHR24064:SF462 SOLUTE CARRIER FAMILY 22 MEMBER SI:DKEY-190L8.2 ISOFORM X1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000010467.1|UniProtKB=W5MWS0 W5MWS0 PTHR10073:SF47 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL DNA MISMATCH REPAIR PROTEIN MLH3 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005465.1|UniProtKB=W5MDY0 W5MDY0 PTHR31428:SF7 RGM DOMAIN FAMILY MEMBER DRAG-1 RGM DOMAIN FAMILY, MEMBER D ISOFORM X1 coreceptor activity#GO:0015026;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010018.1|UniProtKB=W5MV41 W5MV41 PTHR21737:SF21 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 MARVEL DOMAIN CONTAINING 3 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010593.1|UniProtKB=W5MX59 W5MX59 PTHR12121:SF45 CARBON CATABOLITE REPRESSOR PROTEIN 4 NOCTURNIN 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527 positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000016986.1|UniProtKB=W5NK40 W5NK40 PTHR10663:SF333 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PROTEIN MON2 HOMOLOG retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;cytosolic transport#GO:0016482;protein localization to vacuole#GO:0072665;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000015534.1|UniProtKB=W5NER1 W5NER1 PTHR10159:SF388 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 9 protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000015462.1|UniProtKB=W5NEH0 W5NEH0 PTHR15682:SF2 UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000004322.1|UniProtKB=W5M9X1 W5M9X1 PTHR23113:SF224 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;positive regulation of neuron projection development#GO:0010976;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 Integrin signalling pathway#P00034>C3G#P00929 LEPOC|Ensembl=ENSLOCG00000010137.1|UniProtKB=W5MVJ9 W5MVJ9 PTHR45807:SF1 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;hormone receptor binding#GO:0051427;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;response to stress#GO:0006950;response to hormone#GO:0009725;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;response to peptide#GO:1901652;response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;developmental process#GO:0032502;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;cellular response to nitrogen compound#GO:1901699;hemopoiesis#GO:0030097;response to other organism#GO:0051707;homeostasis of number of cells#GO:0048872;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;erythrocyte differentiation#GO:0030218;tumor necrosis factor-mediated signaling pathway#GO:0033209;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;homeostatic process#GO:0042592;response to external biotic stimulus#GO:0043207;cellular response to peptide hormone stimulus#GO:0071375;response to chemokine#GO:1990868;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to type II interferon#GO:0034341;cellular process#GO:0009987;defense response to other organism#GO:0098542;cell surface receptor signaling pathway via STAT#GO:0097696;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;myeloid cell differentiation#GO:0030099;cell development#GO:0048468;innate immune response#GO:0045087;multicellular organismal-level homeostasis#GO:0048871;defense response#GO:0006952;response to tumor necrosis factor#GO:0034612;immune response#GO:0006955;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;chemokine-mediated signaling pathway#GO:0070098;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cellular response to chemokine#GO:1990869 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor tyrosine protein kinase#PC00168 PDGF signaling pathway#P00047>Jak#P01155;PI3 kinase pathway#P00048>JAK#P01176;CCKR signaling map#P06959>JAK2#P07156;Interferon-gamma signaling pathway#P00035>Jak2#P00952;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>JAK#P00846;JAK/STAT signaling pathway#P00038>Jak#P01034 LEPOC|Ensembl=ENSLOCG00000003694.1|UniProtKB=W5M7N7 W5M7N7 PTHR10121:SF0 COATOMER SUBUNIT DELTA COATOMER SUBUNIT DELTA structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;Golgi vesicle transport#GO:0048193;organelle localization#GO:0051640;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;vesicle membrane#GO:0012506;membrane#GO:0016020;COPI-coated vesicle#GO:0030137;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150;vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000016588.1|UniProtKB=W5NIN3 W5NIN3 PTHR12001:SF55 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180;isoprenoid metabolic process#GO:0006720;isoprenoid biosynthetic process#GO:0008299;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234 metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002629.1|UniProtKB=W5M3Y5 W5M3Y5 PTHR19143:SF256 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 4 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857 lipid homeostasis#GO:0055088;triglyceride homeostasis#GO:0070328;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000002695.1|UniProtKB=W5M458 W5M458 PTHR46908:SF10 CUBILIN-LIKE PROTEIN TUMOR NECROSIS FACTOR-INDUCIBLE GENE 6 PROTEIN regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;regulation of response to stress#GO:0080134;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000013515.1|UniProtKB=W5N7Q8 W5N7Q8 PTHR24173:SF1 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 33B scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015894.1|UniProtKB=W5NG12 W5NG12 PTHR11524:SF13 60S RIBOSOMAL PROTEIN L7 RIBOSOMAL PROTEIN UL30-LIKE structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000000233.1|UniProtKB=W5LVV0 W5LVV0 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000017715.1|UniProtKB=W5NMG1 W5NMG1 PTHR24234:SF7 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G PROTEIN-COUPLED RECEPTOR 132-RELATED mitotic cell cycle phase transition#GO:0044772;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of biological process#GO:0048519;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;regulation of cell cycle#GO:0051726;G1/S transition of mitotic cell cycle#GO:0000082;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786;mitotic cell cycle process#GO:1903047;negative regulation of cell cycle G2/M phase transition#GO:1902750;regulation of cell cycle G2/M phase transition#GO:1902749;cell cycle G1/S phase transition#GO:0044843;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016208.1|UniProtKB=W5NH69 W5NH69 PTHR15268:SF4 THRAP3/BCLAF1 BCL-2-ASSOCIATED TRANSCRIPTION FACTOR 1 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014473.1|UniProtKB=W5NB07 W5NB07 PTHR31233:SF12 BICAUDAL D FAMILY MEMBER MGC162200 PROTEIN cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;microtubule anchoring#GO:0034453;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000016079.1|UniProtKB=W5NGQ4 W5NGQ4 PTHR12989:SF10 ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10 DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000012171.1|UniProtKB=W5N2W4 W5N2W4 PTHR20930:SF2 OVARIAN CARCINOMA ANTIGEN CA125-RELATED NEXT TO BRCA1 GENE 1 PROTEIN establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;transport#GO:0006810;vacuolar transport#GO:0007034;macroautophagy#GO:0016236;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;cellular process#GO:0009987;autophagy#GO:0006914;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;establishment of protein localization to vacuole#GO:0072666;catabolic process#GO:0009056 autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 LEPOC|Ensembl=ENSLOCG00000003702.1|UniProtKB=W5M7P7 W5M7P7 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007313.1|UniProtKB=W5MKG4 W5MKG4 PTHR20855:SF15 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to Golgi apparatus#GO:0034067;macromolecule localization#GO:0033036 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005238.1|UniProtKB=W5MD51 W5MD51 PTHR23082:SF0 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001831.1|UniProtKB=W5M163 W5M163 PTHR13227:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2A EUKARYOTIC TRANSLATION INITIATION FACTOR 2A translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2A#P06762 LEPOC|Ensembl=ENSLOCG00000004670.1|UniProtKB=W5MB37 W5MB37 PTHR24034:SF204 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000014577.1|UniProtKB=W5NBD3 W5NBD3 PTHR22984:SF23 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE PIM-2 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of mitotic cell cycle#GO:0007346;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011568.1|UniProtKB=W5N0Q3 W5N0Q3 PTHR17206:SF0 PROLACTIN-RELEASING PEPTIDE C-RF AMIDE PEPTIDE LEPOC|Ensembl=ENSLOCG00000009086.1|UniProtKB=W5MRS5 W5MRS5 PTHR23097:SF90 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11B transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009910.1|UniProtKB=W5MUR0 W5MUR0 PTHR24060:SF23 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 4 adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000005330.1|UniProtKB=W5MDG7 W5MDG7 PTHR45862:SF1 PROTEIN SGT1 HOMOLOG PROTEIN SGT1 HOMOLOG LEPOC|Ensembl=ENSLOCG00000012423.1|UniProtKB=W5N3T9 W5N3T9 MAX PTHR10328:SF3 PROTEIN MAX MYC-ASSOCIATED FACTOR X PROTEIN MAX DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 Oxidative stress response#P00046>Max#P01133 LEPOC|Ensembl=ENSLOCG00000014464.1|UniProtKB=W5NAZ6 W5NAZ6 PTHR15668:SF5 JM1 PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 22 protein binding#GO:0005515;binding#GO:0005488 endocytic recycling#GO:0032456;regulation of biological process#GO:0050789;cellular localization#GO:0051641;positive regulation of metabolic process#GO:0009893;regulation of intracellular signal transduction#GO:1902531;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;vesicle-mediated transport#GO:0016192;positive regulation of macromolecule metabolic process#GO:0010604;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;endosomal transport#GO:0016197;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;localization#GO:0051179;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;localization within membrane#GO:0051668;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;regulation of catabolic process#GO:0009894;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;regulation of response to stimulus#GO:0048583;transport#GO:0006810 LEPOC|Ensembl=ENSLOCG00000017798.1|UniProtKB=W5NMP3 W5NMP3 PTHR10614:SF7 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 2 signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068 phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;regulation of biological process#GO:0050789;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to peptide hormone stimulus#GO:0071375;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;insulin-like growth factor receptor signaling pathway#GO:0048009;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759;Interleukin signaling pathway#P00036>IRS1/2#P00980;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899 LEPOC|Ensembl=ENSLOCG00000008344.1|UniProtKB=W5MP27 W5MP27 PTHR18945:SF571 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3 transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089 anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;trans-synaptic signaling#GO:0099537;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810 cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;plasma membrane#GO:0005886;GABA-ergic synapse#GO:0098982;plasma membrane region#GO:0098590;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;cell junction#GO:0030054 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000004584.1|UniProtKB=W5MAS7 W5MAS7 PTHR28336:SF1 BA1-643 SIMILAR TO CDNA SEQUENCE BC005537 LEPOC|Ensembl=ENSLOCG00000017409.1|UniProtKB=W5NLK5 W5NLK5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006988.1|UniProtKB=W5MJ94 W5MJ94 PTHR46693:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 LEPOC|Ensembl=ENSLOCG00000000028.1|UniProtKB=W5LV75 W5LV75 PTHR24253:SF144 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008812.1|UniProtKB=W5MQR3 W5MQR3 PTHR13232:SF11 NAD(P)H-HYDRATE EPIMERASE NAD(P)H-HYDRATE EPIMERASE catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;isomerase activity#GO:0016853 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;epimerase/racemase#PC00096 LEPOC|Ensembl=ENSLOCG00000007535.1|UniProtKB=W5MLA2 W5MLA2 PTHR23076:SF144 METALLOPROTEASE M41 FTSH ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1 peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteolysis#GO:0006508;mitochondrion organization#GO:0007005;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000017015.1|UniProtKB=W5NK77 W5NK77 PTHR11584:SF332 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cellular process#GO:0050794;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;response to stimulus#GO:0050896;signaling#GO:0023052;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;MAPK cascade#GO:0000165;neuron apoptotic process#GO:0051402;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;JNK cascade#GO:0007254;p38MAPK cascade#GO:0038066;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;apoptotic signaling pathway#GO:0097190 non-receptor serine/threonine protein kinase#PC00167 p38 MAPK pathway#P05918>ASK1#P06043;Integrin signalling pathway#P00034>ERK#P00907;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;Apoptosis signaling pathway#P00006>ASK1#P00272;FGF signaling pathway#P00021>MEKK1-5#P00634;FAS signaling pathway#P00020>ASK1#P00614;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 LEPOC|Ensembl=ENSLOCG00000007242.1|UniProtKB=W5MK59 W5MK59 PTHR46983:SF4 CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000008216.1|UniProtKB=W5MNM0 W5MNM0 PTHR46478:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3A LEPOC|Ensembl=ENSLOCG00000002353.1|UniProtKB=W5M306 W5M306 PTHR13768:SF2 SOLUBLE NSF ATTACHMENT PROTEIN SNAP GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014489.1|UniProtKB=W5NB24 W5NB24 PTHR10807:SF40 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3-PHOSPHATE PHOSPHATASE MTMR1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;dephosphorylation#GO:0016311;lipid modification#GO:0030258 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000009761.1|UniProtKB=W5MU65 W5MU65 PTHR24278:SF34 COAGULATION FACTOR COAGULATION FACTOR VII PRECURSOR endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;blood coagulation#GO:0007596;response to wounding#GO:0009611;response to stress#GO:0006950;coagulation#GO:0050817;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;biological regulation#GO:0065007;biosynthetic process#GO:0009058;proteolysis#GO:0006508;protein metabolic process#GO:0019538;wound healing#GO:0042060;regulation of biological quality#GO:0065008;hemostasis#GO:0007599;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000017027.1|UniProtKB=W5NK98 W5NK98 PTHR11477:SF10 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN PHD FINGER PROTEIN 3 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001815.1|UniProtKB=W5M136 W5M136 PTHR31501:SF5 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 PROTEIN ORAI-2 monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085 transport#GO:0006810;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000017314.1|UniProtKB=W5NLB0 W5NLB0 PTHR40250:SF1 CHROMOSOME 11 OPEN READING FRAME 96 SI:CH1073-281M9.1 LEPOC|Ensembl=ENSLOCG00000002687.1|UniProtKB=W5M447 W5M447 PTHR10701:SF24 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN N protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 cytoplasm#GO:0005737;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148 Gonadotropin-releasing hormone receptor pathway#P06664>SNURF#P06808 LEPOC|Ensembl=ENSLOCG00000004107.1|UniProtKB=W5M969 W5M969 PTHR23280:SF12 4.1 G PROTEIN PROTEIN 4.1 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 Nicotine pharmacodynamics pathway#P06587>EPB41#P06607;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 LEPOC|Ensembl=ENSLOCG00000001913.1|UniProtKB=W5M1K5 W5M1K5 PTHR15720:SF12 GREB1-RELATED GREB1-LIKE PROTEIN animal organ development#GO:0048513;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;multicellular organism development#GO:0007275;morphogenesis of an epithelium#GO:0002009;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;renal system development#GO:0072001;kidney development#GO:0001822;anatomical structure morphogenesis#GO:0009653 LEPOC|Ensembl=ENSLOCG00000017824.1|UniProtKB=W5NMR8 W5NMR8 PTHR22639:SF13 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3-LIKE viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000015966.1|UniProtKB=W5NGA0 W5NGA0 PTHR12573:SF4 AT09986P-RELATED AT09986P-RELATED LEPOC|Ensembl=ENSLOCG00000001779.1|UniProtKB=W5M101 W5M101 PTHR43725:SF58 UDP-GLUCOSE 4-EPIMERASE UDP-GLUCOSE 4-EPIMERASE racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;isomerase activity#GO:0016853 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 epimerase/racemase#PC00096 Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965 LEPOC|Ensembl=ENSLOCG00000008030.1|UniProtKB=W5MMZ8 W5MMZ8 PTHR12550:SF41 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000017697.1|UniProtKB=W5NME3 W5NME3 PTHR24228:SF77 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR B2 BRADYKININ RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000136.1|UniProtKB=W5LVJ0 W5LVJ0 PTHR31019:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 14 SMALL INTEGRAL MEMBRANE PROTEIN 14 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000001776.1|UniProtKB=W5M0Z2 W5M0Z2 PTHR10165:SF14 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 3 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;dephosphorylation#GO:0016311;cell communication#GO:0007154;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;phospholipid metabolic process#GO:0006644 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015713.1|UniProtKB=W5NFD4 W5NFD4 PTHR46186:SF12 CYSTATIN CYSTATIN C (AMYLOID ANGIOPATHY AND CEREBRAL HEMORRHAGE)-RELATED molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 extracellular region#GO:0005576;vesicle#GO:0031982;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000001512.1|UniProtKB=W5M023 W5M023 PTHR43788:SF20 DNA2/NAM7 HELICASE FAMILY MEMBER DNA-BINDING PROTEIN SMUBP-2 catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stress#GO:0006950;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000017988.1|UniProtKB=W5NN80 W5NN80 PTHR23105:SF38 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER NHP2-LIKE PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;rRNA processing#GO:0006364 spliceosomal snRNP complex#GO:0097525;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;nucleolus#GO:0005730;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;small-subunit processome#GO:0032040;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005848.1|UniProtKB=W5MFA1 W5MFA1 PTHR23255:SF58 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1C transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089;activin binding#GO:0048185;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;activin receptor signaling pathway#GO:0032924;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;signaling receptor complex#GO:0043235;catalytic complex#GO:1902494;transferase complex#GO:1990234 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283 LEPOC|Ensembl=ENSLOCG00000006363.1|UniProtKB=W5MH35 W5MH35 PTHR11566:SF199 DYNAMIN INTERFERON-INDUCED GTP-BINDING PROTEIN MXC-RELATED protein binding#GO:0005515;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;microtubule binding#GO:0008017;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817 synaptic vesicle endocytosis#GO:0048488;response to external biotic stimulus#GO:0043207;organelle localization#GO:0051640;response to virus#GO:0009615;localization#GO:0051179;vesicle localization#GO:0051648;synaptic vesicle recycling#GO:0036465;response to other organism#GO:0051707;membrane organization#GO:0061024;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;defense response#GO:0006952;vesicle budding from membrane#GO:0006900;response to external stimulus#GO:0009605;cellular component organization#GO:0016043;defense response to virus#GO:0051607;endocytosis#GO:0006897;establishment of organelle localization#GO:0051656;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;cellular localization#GO:0051641;response to stress#GO:0006950;synaptic vesicle transport#GO:0048489;organelle organization#GO:0006996;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011541.1|UniProtKB=W5N0N5 W5N0N5 PTHR11453:SF10 ANION EXCHANGE PROTEIN ELECTROGENIC SODIUM BICARBONATE COTRANSPORTER 1 monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106 establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000008789.1|UniProtKB=W5MQP1 W5MQP1 PTHR13693:SF79 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991 transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000000385.1|UniProtKB=W5LWB3 W5LWB3 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000016196.1|UniProtKB=W5NH55 W5NH55 PTHR11353:SF23 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT BETA metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457 cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein folding chaperone complex#GO:0101031;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;chaperonin-containing T-complex#GO:0005832 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000010106.1|UniProtKB=W5MVH4 W5MVH4 PTHR47330:SF1 POLY(U)-BINDING-SPLICING FACTOR PUF60-B-RELATED POLY(U)-BINDING-SPLICING FACTOR PUF60 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000009443.1|UniProtKB=W5MT31 W5MT31 PTHR12507:SF3 REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED RAB6A-GEF COMPLEX PARTNER PROTEIN 2 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045 LEPOC|Ensembl=ENSLOCG00000010698.1|UniProtKB=W5MXJ8 W5MXJ8 PTHR18945:SF514 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;signaling receptor activity#GO:0038023;ligand-gated channel activity#GO:0022834;neurotransmitter receptor activity#GO:0030594;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276 anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;synapse assembly#GO:0007416;signaling#GO:0023052;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;animal gross anatomical part developmental process#GO:0160108;cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;chloride transport#GO:0006821 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;cell projection membrane#GO:0031253;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;dendrite#GO:0030425;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;cell junction#GO:0030054;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000000348.1|UniProtKB=W5LW72 W5LW72 PTHR47266:SF40 ENDONUCLEASE-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000004355.1|UniProtKB=W5MA02 W5MA02 PTHR45700:SF3 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3B catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000002825.1|UniProtKB=W5M4L9 W5M4L9 PTHR47977:SF10 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-36 nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000002015.1|UniProtKB=W5M1S9 W5M1S9 PTHR31367:SF2 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1A catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;purine nucleoside metabolic process#GO:0042278;nucleobase-containing small molecule metabolic process#GO:0055086 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000016660.1|UniProtKB=W5NIX1 W5NIX1 PTHR14927:SF0 NUCLEOLAR PROTEIN 10 NUCLEOLAR PROTEIN 10 RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000014545.1|UniProtKB=W5NB96 W5NB96 PTHR10075:SF108 BASIGIN RELATED NEUROPLASTIN cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001011.1|UniProtKB=W5LYF1 W5LYF1 PTHR11920:SF477 GUANYLYL CYCLASE GUANYLATE CYCLASE D peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;lyase activity#GO:0016829;molecular transducer activity#GO:0060089 ribonucleotide metabolic process#GO:0009259;detection of chemical stimulus involved in sensory perception#GO:0050907;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nervous system process#GO:0050877;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;detection of chemical stimulus#GO:0009593;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;sensory perception of smell#GO:0007608;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;detection of stimulus involved in sensory perception#GO:0050906;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;response to chemical#GO:0042221;sensory perception#GO:0007600;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;sensory perception of chemical stimulus#GO:0007606;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;system process#GO:0003008;detection of stimulus#GO:0051606;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;multicellular organismal process#GO:0032501;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007 cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 lyase#PC00144;guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000016971.1|UniProtKB=W5NK20 W5NK20 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740 post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000017041.1|UniProtKB=W5NKA5 W5NKA5 PTHR46532:SF11 MALE FERTILITY FACTOR KL5 DYNEIN AXONEMAL HEAVY CHAIN 12 LEPOC|Ensembl=ENSLOCG00000014817.1|UniProtKB=W5NC87 W5NC87 PTHR43888:SF9 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 4 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;ATPase activator activity#GO:0001671 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to heat#GO:0034605;response to heat#GO:0009408;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein refolding#GO:0042026;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;protein folding#GO:0006457 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000006239.1|UniProtKB=W5MGM6 W5MGM6 PTHR24173:SF16 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 24 multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011059.1|UniProtKB=W5MYW4 W5MYW4 PTHR11848:SF243 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 7 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;signaling#GO:0023052;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000018306.1|UniProtKB=W5NP48 W5NP48 PTHR10231:SF109 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-SUGAR TRANSPORTER PROTEIN SLC35A4-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009952.1|UniProtKB=W5MUW1 W5MUW1 PTHR46791:SF13 EXPRESSED PROTEIN INTEGRASE CORE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013810.1|UniProtKB=W5N8S2 W5N8S2 PTHR13693:SF50 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE, NON-SPECIFIC, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;porphyrin-containing compound biosynthetic process#GO:0006779;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;pigment metabolic process#GO:0042440;primary metabolic process#GO:0044238;heme biosynthetic process#GO:0006783;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole biosynthetic process#GO:0033014 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000011852.1|UniProtKB=W5N1R9 W5N1R9 PTHR13421:SF16 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;snRNA transcription#GO:0009301;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase III#GO:0042796 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000007273.1|UniProtKB=W5MK97 W5MK97 PTHR10921:SF2 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular localization#GO:0051641;spindle localization#GO:0051653;establishment or maintenance of cell polarity#GO:0007163;nuclear division#GO:0000280;microtubule-based transport#GO:0099111;establishment of organelle localization#GO:0051656;centrosome localization#GO:0051642;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;establishment of vesicle localization#GO:0051650;chromosome localization#GO:0050000;organelle transport along microtubule#GO:0072384;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;supramolecular fiber organization#GO:0097435;organelle localization#GO:0051640;mitotic cell cycle#GO:0000278;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;establishment of cell polarity#GO:0030010;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;mitotic cell cycle process#GO:1903047;vesicle cytoskeletal trafficking#GO:0099518;microtubule polymerization#GO:0046785;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;cell migration#GO:0016477;microtubule polymerization or depolymerization#GO:0031109;establishment of spindle localization#GO:0051293;vesicle localization#GO:0051648 chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule organizing center#GO:0005815;centrosome#GO:0005813;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000013001.1|UniProtKB=W5N5V4 W5N5V4 LIAS PTHR10949:SF0 LIPOYL SYNTHASE LIPOYL SYNTHASE, MITOCHONDRIAL transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Lipoate_biosynthesis#P02750>Lipoate synthase#P03004 LEPOC|Ensembl=ENSLOCG00000001177.1|UniProtKB=W5LYW6 W5LYW6 PTHR10258:SF4 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-3 ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 action potential#GO:0001508;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;metal ion transport#GO:0030001;nervous system process#GO:0050877;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;response to calcium ion#GO:0051592;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;detection of stimulus#GO:0051606;cellular process#GO:0009987;potassium ion transport#GO:0006813;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;response to metal ion#GO:0010038;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;system process#GO:0003008;transmission of nerve impulse#GO:0019226 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000008506.1|UniProtKB=W5MPP5 W5MPP5 PTHR45721:SF3 LAMIN DM0-RELATED LAMIN-B1 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 organelle localization#GO:0051640;localization within membrane#GO:0051668;localization#GO:0051179;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;transport#GO:0006810;establishment of localization#GO:0051234;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;macromolecule localization#GO:0033036;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;membrane organization#GO:0061024;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular localization#GO:0051641;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256 organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 FAS signaling pathway#P00020>Nuclear Lamin#P00616 LEPOC|Ensembl=ENSLOCG00000007213.1|UniProtKB=W5MK21 W5MK21 PTHR12558:SF36 CELL DIVISION CYCLE 16,23,27 ANAPHASE-PROMOTING COMPLEX SUBUNIT 7 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;post-translational protein modification#GO:0043687;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;positive regulation of mitotic cell cycle#GO:0045931;macromolecule metabolic process#GO:0043170;regulation of mitotic sister chromatid separation#GO:0010965;cell division#GO:0051301;regulation of cell cycle phase transition#GO:1901987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;regulation of chromosome separation#GO:1905818;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome segregation#GO:0051983;metabolic process#GO:0008152;positive regulation of cell cycle process#GO:0090068;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of organelle organization#GO:0010638 nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005745.1|UniProtKB=W5MEX9 W5MEX9 PTHR11471:SF54 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000000688.1|UniProtKB=W5LXA3 W5LXA3 PTHR15898:SF21 BIFUNCTIONAL APOPTOSIS REGULATOR BIFUNCTIONAL APOPTOSIS REGULATOR acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 LEPOC|Ensembl=ENSLOCG00000013157.1|UniProtKB=W5N6F0 W5N6F0 PTHR12668:SF4 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14C-RELATED pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779;cellular process#GO:0009987;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole biosynthetic process#GO:0033014 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017837.1|UniProtKB=W5NMT1 W5NMT1 PTHR24373:SF394 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE RICH REPEAT CONTAINING 3C signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005544.1|UniProtKB=W5ME88 W5ME88 PTHR10972:SF153 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 2 binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934;alcohol binding#GO:0043178;lipid binding#GO:0008289;cholesterol binding#GO:0015485;steroid binding#GO:0005496 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014818.1|UniProtKB=W5NC88 W5NC88 PTHR11239:SF1 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;response to stimulus#GO:0050896;DNA-templated transcription initiation#GO:0006352;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;DNA-templated transcription elongation#GO:0006354;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 LEPOC|Ensembl=ENSLOCG00000003488.1|UniProtKB=W5M6X7 W5M6X7 PTHR10681:SF180 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-4 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to oxidative stress#GO:0006979;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;response to stress#GO:0006950;cellular process#GO:0009987;catabolic process#GO:0009056;response to stimulus#GO:0050896;homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743 cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000016910.1|UniProtKB=W5NJU9 W5NJU9 PTHR42738:SF16 HYDROXYMETHYLGLUTARYL-COA LYASE 3-HYDROXY-3-METHYLGLUTARYL-COA LYASE, CYTOPLASMIC carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;lyase activity#GO:0016829 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000001038.1|UniProtKB=W5LYF4 W5LYF4 PTHR17103:SF11 NEUREXOPHILIN NEUREXOPHILIN-2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007 GABA-ergic synapse#GO:0098982;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010990.1|UniProtKB=W5MYM1 W5MYM1 PTHR11950:SF40 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 connective tissue development#GO:0061448;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;biological regulation#GO:0065007;hemopoiesis#GO:0030097;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;chondrocyte differentiation#GO:0002062;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;cartilage development#GO:0051216;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;ossification#GO:0001503;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cellular process#GO:0009987;skeletal system development#GO:0001501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 Runt transcription factor#PC00254;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014515.1|UniProtKB=W5NB54 W5NB54 PTHR10242:SF2 8-OXOGUANINE DNA GLYCOSYLASE N-GLYCOSYLASE_DNA LYASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004759.1|UniProtKB=W5MBF0 W5MBF0 PTHR45964:SF9 WSCD FAMILY MEMBER CG9164 SIALATE:O-SULFOTRANSFERASE 2 LEPOC|Ensembl=ENSLOCG00000007636.1|UniProtKB=W5MLL5 W5MLL5 PTHR23075:SF0 PUTATIVE ATP-ASE ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3A cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000017646.1|UniProtKB=W5NM92 W5NM92 PTHR26450:SF44 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51M1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005695.1|UniProtKB=W5MES1 W5MES1 PTHR23389:SF33 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 CHROMOSOME TRANSMISSION FIDELITY PROTEIN 18 HOMOLOG catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002153.1|UniProtKB=W5M299 W5M299 PTHR11431:SF23 FERRITIN FERRITIN ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 storage protein#PC00210 LEPOC|Ensembl=ENSLOCG00000011893.1|UniProtKB=W5N1W6 W5N1W6 PTHR47522:SF2 SALVADOR FAMILY WW DOMAIN-CONTAINING PROTEIN 1 PROTEIN SALVADOR HOMOLOG 1 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;negative regulation of cell population proliferation#GO:0008285;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;hippo signaling#GO:0035329;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;signaling#GO:0023052 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011442.1|UniProtKB=W5N098 W5N098 PTHR11633:SF2 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR SUBUNIT B binding#GO:0005488;signaling receptor binding#GO:0005102;growth factor receptor binding#GO:0070851;protein binding#GO:0005515 enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of MAPK cascade#GO:0043410;positive regulation of locomotion#GO:0040017;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;regulation of ERK1 and ERK2 cascade#GO:0070372;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224;PDGF signaling pathway#P00047>PDGF#P01170 LEPOC|Ensembl=ENSLOCG00000000883.1|UniProtKB=W5LXY0 W5LXY0 PTHR18949:SF0 CALDESMON CALDESMON protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000000171.1|UniProtKB=W5LVN5 W5LVN5 PTHR18884:SF128 SEPTIN SI:CH211-282J17.13-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301;macromolecule localization#GO:0033036;cell cycle#GO:0007049 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000011797.1|UniProtKB=W5N1J8 W5N1J8 PTHR15361:SF1 RAD51/NUKS-INTERACTING PROTEIN NUCLEAR UBIQUITOUS CASEIN AND CYCLIN-DEPENDENT KINASE SUBSTRATE 1 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;response to stress#GO:0006950;cellular process#GO:0009987;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014749.1|UniProtKB=W5NC01 W5NC01 PTHR47981:SF6 RAB FAMILY RAS-RELATED PROTEIN RAB-7B hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 vacuole organization#GO:0007033;localization#GO:0051179;cellular localization#GO:0051641;endosome to lysosome transport#GO:0008333;organelle assembly#GO:0070925;lysosomal transport#GO:0007041;vesicle fusion#GO:0006906;endocytosis#GO:0006897;cellular component organization#GO:0016043;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;lytic vacuole organization#GO:0080171;phagolysosome assembly#GO:0001845;intracellular transport#GO:0046907;phagocytosis#GO:0006909;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;phagocytic vesicle#GO:0045335;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000006771.1|UniProtKB=W5MIH8 W5MIH8 PTHR10504:SF16 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED PHOSPHOLIPID TRANSFER PROTEIN transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014 lipid localization#GO:0010876;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;ceramide transport#GO:0035627;organophosphate ester transport#GO:0015748;transport#GO:0006810;protein-containing complex organization#GO:0043933;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;lipid transport#GO:0006869 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002822.1|UniProtKB=W5M4L2 W5M4L2 PTHR10498:SF10 PARALEMMIN-RELATED PALM2-AKAP2 FUSION LEPOC|Ensembl=ENSLOCG00000006326.1|UniProtKB=W5MGX5 W5MGX5 PTHR11158:SF22 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING PROTEIN 3B molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013 phospholipid transport#GO:0015914;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;macromolecule localization#GO:0033036;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876 organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000012418.1|UniProtKB=W5N3T0 W5N3T0 PTHR23227:SF87 BUCENTAUR RELATED PROTEIN CFDP2 LEPOC|Ensembl=ENSLOCG00000015231.1|UniProtKB=W5NDN3 W5NDN3 PTHR24067:SF243 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 A catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;DNA damage response#GO:0006974;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;membraneless organelle#GO:0043228;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000014505.1|UniProtKB=W5NB45 W5NB45 PTHR48112:SF43 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B3 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000011421.1|UniProtKB=W5N076 W5N076 PTHR12622:SF37 DELTEX-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011949.1|UniProtKB=W5N243 W5N243 PTHR11468:SF3 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, LIVER FORM hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;glycogen catabolic process#GO:0005980;cellular process#GO:0009987;energy reserve metabolic process#GO:0006112;carbohydrate catabolic process#GO:0016052;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;glycogen metabolic process#GO:0005977;polysaccharide catabolic process#GO:0000272;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 LEPOC|Ensembl=ENSLOCG00000004744.1|UniProtKB=W5MBF6 W5MBF6 PTHR11496:SF83 ALCOHOL DEHYDROGENASE HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000010206.1|UniProtKB=W5MVT7 W5MVT7 PTHR13793:SF84 PHD FINGER PROTEINS E3 UBIQUITIN-PROTEIN LIGASE JADE-2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000003894.1|UniProtKB=W5M8E1 W5M8E1 PTHR14027:SF2 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017565.1|UniProtKB=W5NM11 W5NM11 PTHR16271:SF10 F-BOX ONLY PROTEIN 34/46 FAMILY MEMBER F-BOX ONLY PROTEIN 46 LEPOC|Ensembl=ENSLOCG00000001343.1|UniProtKB=W5LZG3 W5LZG3 PTHR10129:SF26 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFK cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001638.1|UniProtKB=W5M0I0 W5M0I0 PTHR13759:SF8 TWINFILIN TWINFILIN-1 actin monomer binding#GO:0003785;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;protein depolymerization#GO:0051261;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;protein-containing complex disassembly#GO:0032984;regulation of actin filament depolymerization#GO:0030834;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;regulation of cell projection assembly#GO:0060491;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;actin filament depolymerization#GO:0030042;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;cellular component disassembly#GO:0022411 contractile muscle fiber#GO:0043292;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;actin filament#GO:0005884;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000005566.1|UniProtKB=W5MEB3 W5MEB3 PTHR12316:SF28 NINJURIN-RELATED NINJURIN-2-LIKE cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515 cell adhesion#GO:0007155;cell death#GO:0008219;cellular process#GO:0009987;programmed cell death#GO:0012501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012062.1|UniProtKB=W5N2I1 W5N2I1 PTHR16284:SF13 PROTEIN CDV3 HOMOLOG PROTEIN CDV3 HOMOLOG cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014683.1|UniProtKB=W5NBS4 W5NBS4 PTHR12609:SF0 MICROTUBULE ASSOCIATED PROTEIN XMAP215 CYTOSKELETON-ASSOCIATED PROTEIN 5 microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule organizing center organization#GO:0031023;mitotic cell cycle process#GO:1903047;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;centrosome cycle#GO:0007098;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;establishment or maintenance of cell polarity#GO:0007163 chromosome#GO:0005694;spindle pole#GO:0000922;microtubule end#GO:1990752;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;microtubule#GO:0005874;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000010494.1|UniProtKB=W5MWV4 W5MWV4 PTHR10024:SF45 SYNAPTOTAGMIN SYNAPTOTAGMIN-6 phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149;molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;protein binding#GO:0005515 trans-synaptic signaling#GO:0099537;localization#GO:0051179;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;transport#GO:0006810;establishment of localization#GO:0051234;regulation of localization#GO:0032879;regulation of transport#GO:0051049;synaptic signaling#GO:0099536;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000006252.1|UniProtKB=W5MGP8 W5MGP8 PTHR24027:SF79 CADHERIN-23 CADHERIN-2 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cell motility#GO:0048870;cell junction organization#GO:0034330;synapse assembly#GO:0007416;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;cell adhesion#GO:0007155;multicellular organismal process#GO:0032501;cell migration#GO:0016477;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502 neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;lamellipodium#GO:0030027;protein-containing complex#GO:0032991;apical part of cell#GO:0045177;cell-cell contact zone#GO:0044291;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;intercalated disc#GO:0014704;intracellular anatomical structure#GO:0005622 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000006327.1|UniProtKB=W5MGX8 W5MGX8 PTHR12111:SF2 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2B-RELATED intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000000957.1|UniProtKB=W5LY66 W5LY66 PTHR46831:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000004847.1|UniProtKB=W5MBT1 W5MBT1 PTHR13817:SF75 TITIN PROTEIN TURTLE HOMOLOG B structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011732.1|UniProtKB=W5N1B1 W5N1B1 PTHR24200:SF6 TOUCAN, ISOFORM A COILED-COIL DOMAIN-CONTAINING PROTEIN 69 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000011228.1|UniProtKB=W5MZI7 W5MZI7 PTHR24070:SF414 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY INTRAFLAGELLAR TRANSPORT PROTEIN 27 HOMOLOG protein kinase activator activity#GO:0030295;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 cell communication#GO:0007154;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;positive regulation of TORC1 signaling#GO:1904263;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000007006.1|UniProtKB=W5MJB6 W5MJB6 PTHR31021:SF3 ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 PROTEIN APCDD1-LIKE LEPOC|Ensembl=ENSLOCG00000015072.1|UniProtKB=W5ND41 W5ND41 PTHR12905:SF31 METALLOPHOSPHOESTERASE METALLOPHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN 1 cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121;esterase#PC00097;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012444.1|UniProtKB=W5N3V8 W5N3V8 PTHR23349:SF3 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HEART- AND NEURAL CREST DERIVATIVES-EXPRESSED PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;circulatory system development#GO:0072359;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;heart development#GO:0007507;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000001242.1|UniProtKB=W5LZ57 W5LZ57 PTHR10201:SF297 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-20 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000002077.1|UniProtKB=W5M214 W5M214 PTHR46299:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2-RELATED VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B1 LEPOC|Ensembl=ENSLOCG00000000862.1|UniProtKB=W5LXW0 W5LXW0 PTHR10489:SF627 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 8 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023 calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemotaxis#GO:0006935;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;locomotion#GO:0040011;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000011055.1|UniProtKB=W5MYW2 W5MYW2 PTHR11349:SF116 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE B nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular process#GO:0009987;metabolic process#GO:0008152;nucleoside triphosphate biosynthetic process#GO:0009142;phosphorus metabolic process#GO:0006793;biosynthetic process#GO:0009058;nucleoside triphosphate metabolic process#GO:0009141 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 kinase#PC00137;transferase#PC00220 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 LEPOC|Ensembl=ENSLOCG00000010920.1|UniProtKB=W5MYD2 W5MYD2 PTHR24248:SF0 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2DA ADRENERGIC RECEPTOR-RELATED G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;hormone binding#GO:0042562;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002685.1|UniProtKB=W5M444 W5M444 PTHR15929:SF0 STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of biological process#GO:0050789 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000007628.1|UniProtKB=W5MLK5 W5MLK5 PTHR10807:SF42 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR2 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;dephosphorylation#GO:0016311;lipid modification#GO:0030258;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004380.1|UniProtKB=W5MA29 W5MA29 PTHR24058:SF53 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 3 transcription regulator activity#GO:0140110;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transcription coregulator activity#GO:0003712;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713 response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;signaling#GO:0023052;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;smoothened signaling pathway#GO:0007224 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011126.1|UniProtKB=W5MZ64 W5MZ64 PTHR12296:SF17 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN 4C enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;response to nitrogen compound#GO:1901698;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000011549.1|UniProtKB=W5N0N3 W5N0N3 PTHR12747:SF0 ELONGATOR COMPLEX PROTEIN 1 ELONGATOR COMPLEX PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049 RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;elongator holoenzyme complex#GO:0033588;cytoplasm#GO:0005737;cytosol#GO:0005829 general transcription factor#PC00259 PDGF signaling pathway#P00047>Ikk#P01146 LEPOC|Ensembl=ENSLOCG00000006005.1|UniProtKB=W5MFV2 W5MFV2 PTHR10681:SF111 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-1 peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular process#GO:0009987;cellular oxidant detoxification#GO:0098869;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;cellular homeostasis#GO:0019725;response to reactive oxygen species#GO:0000302;cell redox homeostasis#GO:0045454;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000016511.1|UniProtKB=W5NID6 W5NID6 PTHR11941:SF27 ENOYL-COA HYDRATASE-RELATED ETHYLMALONYL-COA DECARBOXYLASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;lyase activity#GO:0016829 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;hydratase#PC00120;lyase#PC00144 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 LEPOC|Ensembl=ENSLOCG00000015110.1|UniProtKB=W5ND89 W5ND89 PTHR24253:SF128 TRANSMEMBRANE PROTEASE SERINE OVOCHYMASE-1 ISOFORM X1 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015421.1|UniProtKB=W5NEB7 W5NEB7 PTHR46541:SF1 ZINC FINGER PROTEIN AEBP2 ZINC FINGER PROTEIN AEBP2 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;PcG protein complex#GO:0031519;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000016672.1|UniProtKB=W5NIY7 W5NIY7 PTHR46517:SF1 FRUCTOSE-2,6-BISPHOSPHATASE TIGAR FRUCTOSE-2,6-BISPHOSPHATASE TIGAR hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of catabolic process#GO:0009895;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of carbohydrate metabolic process#GO:0006109 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 Cobalamin biosynthesis#P02735>Ribazole-5-phosphate phosphatase#P02881 LEPOC|Ensembl=ENSLOCG00000007331.1|UniProtKB=W5MKH1 W5MKH1 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003171.1|UniProtKB=W5M5V1 W5M5V1 PTHR23024:SF603 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE-LIKE 4 cellular anatomical structure#GO:0110165;membrane#GO:0016020 deacetylase#PC00087 LEPOC|Ensembl=ENSLOCG00000007895.1|UniProtKB=W5MMI8 W5MMI8 PTHR13465:SF5 UPF0183 PROTEIN PHAGOSOME ASSEMBLY FACTOR 1 Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;protein localization to cell periphery#GO:1990778 Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;somatodendritic compartment#GO:0036477;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;dendritic tree#GO:0097447;dendrite#GO:0030425;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;intracellular vesicle#GO:0097708;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000009961.1|UniProtKB=W5MUX9 W5MUX9 PTHR23077:SF63 AAA-FAMILY ATPASE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;polyubiquitin modification-dependent protein binding#GO:0031593;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;modification-dependent protein binding#GO:0140030;binding#GO:0005488;ATP-dependent activity#GO:0140657 transport#GO:0006810;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;autophagosome maturation#GO:0097352;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;spindle organization#GO:0007051;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;primary metabolic process#GO:0044238;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of protein localization#GO:0045184;autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;cytoskeleton organization#GO:0007010;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;cell cycle process#GO:0022402;cellular component organization#GO:0016043;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052 membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytosol#GO:0005829;nucleus#GO:0005634;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006869.1|UniProtKB=W5MIU8 W5MIU8 PTHR24377:SF1040 IP01015P-RELATED ZINC FINGER PROTEIN 467 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000017638.1|UniProtKB=W5NM84 W5NM84 C2CD4C PTHR46291:SF5 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4C LEPOC|Ensembl=ENSLOCG00000008264.1|UniProtKB=W5MNT3 W5MNT3 PTHR10110:SF56 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;import across plasma membrane#GO:0098739;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;potassium ion transport#GO:0006813;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000005172.1|UniProtKB=W5MCX3 W5MCX3 PTHR12011:SF58 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR D2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013529.1|UniProtKB=W5N7S6 W5N7S6 PTHR11024:SF21 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER PROTEIN SEC13 HOMOLOG cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;protein transport#GO:0015031;protein import into nucleus#GO:0006606;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle budding from membrane#GO:0006900;intracellular transport#GO:0046907;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;membrane organization#GO:0061024;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;positive regulation of cellular process#GO:0048522;localization#GO:0051179;nuclear transport#GO:0051169;positive regulation of TOR signaling#GO:0032008;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;protein localization to organelle#GO:0033365;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967 organelle membrane#GO:0031090;ER to Golgi transport vesicle membrane#GO:0012507;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;nucleus#GO:0005634;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;vesicle#GO:0031982;nuclear pore outer ring#GO:0031080;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;bounding membrane of organelle#GO:0098588;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vesicle coat#GO:0030120;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;coated membrane#GO:0048475;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017994.1|UniProtKB=W5NN86 W5NN86 PTHR48164:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010664.1|UniProtKB=W5MXG3 W5MXG3 PTHR11588:SF75 TUBULIN TUBULIN ALPHA CHAIN purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;mitotic cell cycle#GO:0000278;cell differentiation#GO:0030154;cellular component organization#GO:0016043;cell cycle#GO:0007049;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630 tubulin#PC00228;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010767.1|UniProtKB=W5MXU8 W5MXU8 PTHR45639:SF5 HSC70CB, ISOFORM G-RELATED HEAT SHOCK 70 KDA PROTEIN 4L nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp70 family chaperone#PC00027 LEPOC|Ensembl=ENSLOCG00000002507.1|UniProtKB=W5M3J7 W5M3J7 PTHR45627:SF7 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 5 cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;ribose phosphate biosynthetic process#GO:0046390;cyclic purine nucleotide metabolic process#GO:0052652;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 adenylate cyclase#PC00043 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;GABA-B receptor II signaling#P05731>AC#P05760;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 LEPOC|Ensembl=ENSLOCG00000010336.1|UniProtKB=W5MWA5 W5MWA5 PTHR24064:SF453 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;quaternary ammonium group transmembrane transporter activity#GO:0015651 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000015028.1|UniProtKB=W5NCZ0 W5NCZ0 PTHR24064:SF198 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000005133.1|UniProtKB=W5MCR9 W5MCR9 PTHR13356:SF5 OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED SOSS COMPLEX SUBUNIT B2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cell cycle phase transition#GO:1901988;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;regulation of biological process#GO:0050789;response to ionizing radiation#GO:0010212;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;recombinational repair#GO:0000725;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle#GO:0007346;response to radiation#GO:0009314;mitotic G2/M transition checkpoint#GO:0044818 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004341.1|UniProtKB=W5M9X2 W5M9X2 PTHR12213:SF0 CORRINOID ADENOSYLTRANSFERASE CORRINOID ADENOSYLTRANSFERASE MMAB transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000013544.1|UniProtKB=W5N7U0 W5N7U0 PTHR46812:SF1 CARBOXYMETHYLENEBUTENOLIDASE HOMOLOG CARBOXYMETHYLENEBUTENOLIDASE HOMOLOG LEPOC|Ensembl=ENSLOCG00000017531.1|UniProtKB=W5NLX7 W5NLX7 PTHR47097:SF1 HEAT SHOCK PROTEIN BETA-3 HEAT SHOCK PROTEIN BETA-3 organelle lumen#GO:0043233;nuclear speck#GO:0016607;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000004159.1|UniProtKB=W5M9C7 W5M9C7 PTHR24023:SF958 COLLAGEN ALPHA THROMBOSPONDIN-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000008170.1|UniProtKB=W5MNF9 W5MNF9 PTHR47385:SF12 CALPONIN CALPONIN-1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017339.1|UniProtKB=W5NLD5 W5NLD5 PTHR10760:SF1 TORSIN TORSIN-4A endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001665.1|UniProtKB=W5M0N2 W5M0N2 PTHR46307:SF2 G9A, ISOFORM B HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006109.1|UniProtKB=W5MG73 W5MG73 PTHR33955:SF2 TRANSMEMBRANE PROTEIN 52 TRANSMEMBRANE PROTEIN 52 LEPOC|Ensembl=ENSLOCG00000005898.1|UniProtKB=W5MFG8 W5MFG8 PTHR10742:SF410 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000012687.1|UniProtKB=W5N4Q2 W5N4Q2 PTHR24343:SF133 SERINE/THREONINE KINASE NUAK FAMILY SNF1-LIKE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to stimulus#GO:0050896;response to nutrient levels#GO:0031667;response to starvation#GO:0042594;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular response to glucose starvation#GO:0042149;cellular process#GO:0009987;cellular response to starvation#GO:0009267;cellular response to stress#GO:0033554;cellular response to nutrient levels#GO:0031669 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004321.1|UniProtKB=W5M9V0 W5M9V0 PTHR24253:SF81 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 9 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;plasminogen activation#GO:0031639;primary metabolic process#GO:0044238;zymogen activation#GO:0031638;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013991.1|UniProtKB=W5N9D6 W5N9D6 PTHR13069:SF36 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 TRNA METHYLTRANSFERASE 9B-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;nucleic acid binding#GO:0003676;binding#GO:0005488;methyltransferase activity#GO:0008168;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012815.1|UniProtKB=W5N558 W5N558 PTHR12113:SF31 DICKKOPF3-LIKE 3 DICKKOPF N-TERMINAL CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;signaling receptor regulator activity#GO:0030545 regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012983.1|UniProtKB=W5N5T0 W5N5T0 PTHR43715:SF1 GDP-MANNOSE 4,6-DEHYDRATASE GDP-MANNOSE 4,6 DEHYDRATASE dehydratase#PC00091;lyase#PC00144 Mannose metabolism#P02752>GDP-Mannose 4,6-dehydratase#P03015 LEPOC|Ensembl=ENSLOCG00000014601.1|UniProtKB=W5NBG0 W5NBG0 PTHR23188:SF12 RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;chromatin binding#GO:0003682;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488 transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593 LEPOC|Ensembl=ENSLOCG00000015248.1|UniProtKB=W5NDQ4 W5NDQ4 PTHR12439:SF33 PLACENTAL PROTEIN 11-RELATED URIDYLATE-SPECIFIC ENDORIBONUCLEASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 LEPOC|Ensembl=ENSLOCG00000000225.1|UniProtKB=W5LVU3 W5LVU3 PTHR22702:SF1 PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000002868.1|UniProtKB=W5M4R0 W5M4R0 PTHR36681:SF3 NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3 NUCLEAR GTPASE, GERMINAL CENTER ASSOCIATED, TANDEM DUPLICATE 3 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000007613.1|UniProtKB=W5MLI5 W5MLI5 PTHR23317:SF65 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 6 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000005906.1|UniProtKB=W5MFI1 W5MFI1 PTHR16023:SF0 TAX1 BINDING PROTEIN-RELATED PROTEIN VAC14 HOMOLOG organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;organophosphate biosynthetic process#GO:0090407 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002182.1|UniProtKB=W5M2E2 W5M2E2 PTHR24115:SF1004 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF15 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000001352.1|UniProtKB=W5LZL5 W5LZL5 PTHR22760:SF2 GLYCOSYLTRANSFERASE ALPHA-1,2-MANNOSYLTRANSFERASE ALG9 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000015739.1|UniProtKB=W5NFG6 W5NFG6 PTHR19444:SF13 UNC-93 RELATED N-ACETYLGLUCOSAMINE TRANSPORTER UNC93A molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000006111.1|UniProtKB=W5MG79 W5MG79 PTHR10219:SF111 GLYCOLIPID TRANSFER PROTEIN-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8 phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;ion binding#GO:0043167;molecular carrier activity#GO:0140104;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;lipid binding#GO:0008289 intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lipid transport#GO:0006869;membrane organization#GO:0061024;lipid localization#GO:0010876;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;ceramide transport#GO:0035627 cytosol#GO:0005829;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014999.1|UniProtKB=W5NCW3 W5NCW3 PTHR24367:SF10 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 3 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 secretory vesicle#GO:0099503;presynapse#GO:0098793;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 LEPOC|Ensembl=ENSLOCG00000009187.1|UniProtKB=W5MS72 W5MS72 PTHR19443:SF10 HEXOKINASE HEXOKINASE-1 hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200 nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;intracellular chemical homeostasis#GO:0055082;energy derivation by oxidation of organic compounds#GO:0015980;ribonucleoside diphosphate metabolic process#GO:0009185;carbohydrate homeostasis#GO:0033500;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;intracellular glucose homeostasis#GO:0001678;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;chemical homeostasis#GO:0048878;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;cellular homeostasis#GO:0019725;ADP metabolic process#GO:0046031;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;glucose homeostasis#GO:0042593 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasmic side of membrane#GO:0098562;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytosol#GO:0005829 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Hexokinase#P00677;Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966 LEPOC|Ensembl=ENSLOCG00000007452.1|UniProtKB=W5MKY2 W5MKY2 PTHR19269:SF38 TROPOMYOSIN TROPOMYOSIN ALPHA-3 CHAIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779 system process#GO:0003008;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;muscle contraction#GO:0006936;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;muscle system process#GO:0003012;cellular component organization#GO:0016043;organelle organization#GO:0006996 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;actin filament#GO:0005884;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000013924.1|UniProtKB=W5N955 W5N955 PTHR10953:SF3 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7 ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity, transferring sulphur-containing groups#GO:0016782;Atg12 activating enzyme activity#GO:0019778;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;protein modification by small protein conjugation#GO:0032446;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to starvation#GO:0042594;vacuole organization#GO:0007033;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;organelle assembly#GO:0070925;post-translational protein modification#GO:0043687;macroautophagy#GO:0016236;response to nutrient levels#GO:0031667;macromolecule metabolic process#GO:0043170;mitophagy#GO:0000423;cellular response to nutrient levels#GO:0031669;autophagy of mitochondrion#GO:0000422;cellular response to starvation#GO:0009267 phagophore assembly site#GO:0000407;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000017469.1|UniProtKB=W5NLR5 W5NLR5 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012052.1|UniProtKB=W5N2G4 W5N2G4 PTHR48099:SF7 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE 2, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 LEPOC|Ensembl=ENSLOCG00000013637.1|UniProtKB=W5N861 W5N861 PTHR11902:SF5 ENOLASE BETA-ENOLASE hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;phosphopyruvate hydratase activity#GO:0004634;catalytic activity#GO:0003824 purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;cytosol#GO:0005829 lyase#PC00144;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006965.1|UniProtKB=W5MJ66 W5MJ66 PTHR21456:SF3 FAMILY WITH SEQUENCE SIMILARITY 102 EEIG FAMILY MEMBER 2 LEPOC|Ensembl=ENSLOCG00000007702.1|UniProtKB=W5MLW0 W5MLW0 PTHR46221:SF9 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FOCAL ADHESION KINASE 1-RELATED VEGF signaling pathway#P00056>FAK#P01420;Integrin signalling pathway#P00034>FAK#P00932;Angiogenesis#P00005>FAK#P00209 LEPOC|Ensembl=ENSLOCG00000001867.1|UniProtKB=W5M1A7 W5M1A7 PTHR15175:SF4 NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2 NADPH OXIDASE ACTIVATOR 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 superoxide metabolic process#GO:0006801;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;regulation of reactive oxygen species metabolic process#GO:2000377;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;cellular process#GO:0009987 catalytic complex#GO:1902494;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000000487.1|UniProtKB=W5LWM6 W5LWM6 PTHR45134:SF5 OS08G0543275 PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007168.1|UniProtKB=W5MJW3 W5MJW3 PTHR22761:SF4 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4B cellular localization#GO:0051641;localization#GO:0051179;late endosome to vacuole transport#GO:0045324;membrane assembly#GO:0071709;cellular component organization#GO:0016043;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;nuclear envelope organization#GO:0006998;endosomal transport#GO:0016197;nucleus organization#GO:0006997;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;multivesicular body sorting pathway#GO:0071985;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;cytoplasmic side of plasma membrane#GO:0009898;vesicle#GO:0031982;side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic side of membrane#GO:0098562 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001207.1|UniProtKB=W5LZ00 W5LZ00 PTHR10201:SF125 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-20 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;catabolic process#GO:0009056;animal organ morphogenesis#GO:0009887;odontogenesis#GO:0042476;metabolic process#GO:0008152;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;anatomical structure formation involved in morphogenesis#GO:0048646;cellular process#GO:0009987;amelogenesis#GO:0097186;odontogenesis of dentin-containing tooth#GO:0042475 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000015290.1|UniProtKB=W5NDV1 W5NDV1 PTHR23245:SF25 TRNA METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;methylation#GO:0032259;carbohydrate derivative metabolic process#GO:1901135;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000012237.1|UniProtKB=W5N344 W5N344 PTHR20855:SF26 ADIPOR/PROGESTIN RECEPTOR-RELATED MONOCYTE TO MACROPHAGE DIFFERENTIATION FACTOR G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002858.1|UniProtKB=W5M4V5 W5M4V5 PTHR10878:SF5 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1-RELATED G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Angiogenesis#P00005>Dsh#P00200;Wnt signaling pathway#P00057>Dishevelled#P01447 LEPOC|Ensembl=ENSLOCG00000007662.1|UniProtKB=W5MLP0 W5MLP0 PTHR10908:SF5 SEROTONIN N-ACETYLTRANSFERASE SEROTONIN N-ACETYLTRANSFERASE acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 circadian rhythm#GO:0007623;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;response to radiation#GO:0009314;photoperiodism#GO:0009648;rhythmic process#GO:0048511;response to abiotic stimulus#GO:0009628 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000007292.1|UniProtKB=W5MKC2 W5MKC2 PTHR14379:SF93 LIMKAIN B LKAP MEIOSIS REGULATOR AND MRNA STABILITY FACTOR 1 binding#GO:0005488;protein-containing complex binding#GO:0044877 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011903.1|UniProtKB=W5N1X8 W5N1X8 PTHR22761:SF77 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4C vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;establishment of localization in cell#GO:0051649;nucleus organization#GO:0006997;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;nuclear envelope organization#GO:0006998;vesicle budding from membrane#GO:0006900;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;membrane assembly#GO:0071709;cellular localization#GO:0051641;localization#GO:0051179 side of membrane#GO:0098552;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic side of plasma membrane#GO:0009898;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic side of membrane#GO:0098562;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;nucleus#GO:0005634 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015429.1|UniProtKB=W5NEC6 W5NEC6 IL22RA2 PTHR20859:SF55 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON LAMBDA RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015715.1|UniProtKB=W5NFD7 W5NFD7 PTHR21661:SF78 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE 1 hydrolase activity#GO:0016787;ether hydrolase activity#GO:0016803;catalytic activity#GO:0003824 fatty acid metabolic process#GO:0006631;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;arachidonate metabolic process#GO:0019369 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015874.1|UniProtKB=W5NFY9 W5NFY9 PTHR13691:SF73 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000016508.1|UniProtKB=W5NID2 W5NID2 PTHR24240:SF0 OPSIN OPSIN-5 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to radiation#GO:0071478;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;detection of stimulus#GO:0051606;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;response to radiation#GO:0009314;signal transduction#GO:0007165;biological regulation#GO:0065007;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010589.1|UniProtKB=W5MX67 W5MX67 PTHR45639:SF6 HSC70CB, ISOFORM G-RELATED HEAT SHOCK 70 KDA PROTEIN 4 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 Hsp70 family chaperone#PC00027;chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007929.1|UniProtKB=W5MMN2 W5MMN2 PTHR12411:SF1077 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN S catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014061.1|UniProtKB=W5N9L8 W5N9L8 PTHR47403:SF2 LOC100145250 PROTEIN N-ACETYLTRANSFERASE 16, LIKE ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000015125.1|UniProtKB=W5NDB2 W5NDB2 PTHR23506:SF31 GH10249P CHROMAFFIN GRANULE AMINE TRANSPORTER active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;solute:sodium symporter activity#GO:0015370;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 axon terminus#GO:0043679;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;axon#GO:0030424;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;terminal bouton#GO:0043195;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular vesicle#GO:0097708;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410;5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418 LEPOC|Ensembl=ENSLOCG00000006076.1|UniProtKB=W5MG25 W5MG25 PTHR14758:SF4 AGAP005440-PA PROTEIN FAM110A LEPOC|Ensembl=ENSLOCG00000002270.1|UniProtKB=W5M2P5 W5M2P5 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002921.1|UniProtKB=W5M4Y5 W5M4Y5 PTHR23239:SF354 INTERMEDIATE FILAMENT KERATIN, TYPE 1, GENE C5 ISOFORM X1 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000007392.1|UniProtKB=W5MKR1 W5MKR1 PTHR13105:SF4 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR 2 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013576.1|UniProtKB=W5N7Y6 W5N7Y6 PTHR11616:SF286 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT NEUTRAL AND BASIC AMINO ACID TRANSPORTER B(0+) secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;branched-chain amino acid transmembrane transporter activity#GO:0015658;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;quaternary ammonium group transmembrane transporter activity#GO:0015651;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370 import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;sodium ion transport#GO:0006814;localization#GO:0051179;monoatomic cation transport#GO:0006812;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000013645.1|UniProtKB=W5N865 W5N865 PTHR10188:SF50 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013984.1|UniProtKB=W5N9C8 W5N9C8 PTHR44140:SF1 LD25575P DNAJ HOMOLOG SUBFAMILY C MEMBER 3 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000008098.1|UniProtKB=W5MN73 W5MN73 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;immune system process#GO:0002376;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;immune response#GO:0006955 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003300.1|UniProtKB=W5M688 W5M688 PTHR43826:SF3 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;phosphate transmembrane transporter activity#GO:0005315;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;inorganic anion transport#GO:0015698;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;organophosphate ester transport#GO:0015748;phosphate ion transport#GO:0006817 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000014695.1|UniProtKB=W5NBT9 W5NBT9 PTHR24372:SF70 GLYCOPROTEIN HORMONE RECEPTOR RELAXIN FAMILY PEPTIDE RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017642.1|UniProtKB=W5NM88 W5NM88 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000007427.1|UniProtKB=W5MKV1 W5MKV1 PTHR12620:SF4 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT ZINC FINGER (CCCH TYPE), RNA-BINDING MOTIF AND SERINE_ARGININE RICH 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;pre-mRNA binding#GO:0036002 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000011300.1|UniProtKB=W5MZS9 W5MZS9 PTHR11346:SF198 GALECTIN GALECTIN binding#GO:0005488;laminin binding#GO:0043236;protein binding#GO:0005515;carbohydrate binding#GO:0030246;extracellular matrix binding#GO:0050840 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000017227.1|UniProtKB=W5NKZ8 W5NKZ8 PTHR13123:SF8 LD30288P F-BOX ONLY PROTEIN 25 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011520.1|UniProtKB=W5N0J7 W5N0J7 PTHR10900:SF82 PERIOSTIN-RELATED TRANSFORMING GROWTH FACTOR-BETA-INDUCED PROTEIN IG-H3 protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell adhesion#GO:0007155;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011090.1|UniProtKB=W5MZ13 W5MZ13 PTHR31711:SF1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000004289.1|UniProtKB=W5M9T2 W5M9T2 PTHR14139:SF3 CALSYNTENIN CALSYNTENIN-2 protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 cell adhesion#GO:0007155;positive regulation of cellular component organization#GO:0051130;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;positive regulation of developmental process#GO:0051094;positive regulation of synapse assembly#GO:0051965;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of synapse assembly#GO:0051963;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239 postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;cell surface#GO:0009986;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015105.1|UniProtKB=W5ND84 W5ND84 PTHR45994:SF3 FI21225P1 PROTEIN UNC-45 HOMOLOG A protein binding#GO:0005515;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;binding#GO:0005488 biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010265.1|UniProtKB=W5MW21 W5MW21 PTHR45679:SF4 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ALPHA-1,2-MANNOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;protein catabolic process#GO:0030163;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;carbohydrate derivative catabolic process#GO:1901136;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;endoplasmic reticulum unfolded protein response#GO:0030968;carbohydrate derivative metabolic process#GO:1901135;biological regulation#GO:0065007;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000007341.1|UniProtKB=W5MKI7 W5MKI7 PTHR10536:SF0 DNA PRIMASE SMALL SUBUNIT DNA PRIMASE SMALL SUBUNIT catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA replication#GO:0006260;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-DNA complex#GO:0032993;organelle#GO:0043226;nucleoplasm#GO:0005654;replication fork#GO:0005657;replisome#GO:0030894;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596 primase#PC00189 DNA replication#P00017>Primase#P00528 LEPOC|Ensembl=ENSLOCG00000012956.1|UniProtKB=W5N5Q0 W5N5Q0 PTHR14663:SF2 METHYLTRANSFERASE NSUN7-RELATED PROTEIN NSUN7 LEPOC|Ensembl=ENSLOCG00000011859.1|UniProtKB=W5N1T6 W5N1T6 PTHR23065:SF57 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 7 vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;import into cell#GO:0098657;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;endocytosis#GO:0006897;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;neurogenesis#GO:0022008;receptor-mediated endocytosis#GO:0006898;neuron projection morphogenesis#GO:0048812;transport#GO:0006810;developmental process#GO:0032502;clathrin-dependent endocytosis#GO:0072583;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731 clathrin-coated vesicle#GO:0030136;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000002950.1|UniProtKB=W5M576 W5M576 PTHR23421:SF199 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318 galactosidase#PC00104;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006792.1|UniProtKB=W5MIM1 W5MIM1 PTHR12039:SF21 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 1 nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 transferase#PC00220;nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000012607.1|UniProtKB=W5N4G4 W5N4G4 PTHR10286:SF50 INORGANIC PYROPHOSPHATASE INORGANIC DIPHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;metabolic process#GO:0008152 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 pyrophosphatase#PC00196 LEPOC|Ensembl=ENSLOCG00000009542.1|UniProtKB=W5MTF3 W5MTF3 PTHR23430:SF37 HISTONE H2A CORE HISTONE MACRO-H2A.2 structural molecule activity#GO:0005198 biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase I#GO:0006356;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;protein-DNA complex#GO:0032993 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010279.1|UniProtKB=W5MW30 W5MW30 PTHR44281:SF5 SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015583.1|UniProtKB=W5NEY1 W5NEY1 PTHR24353:SF68 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKG#P00567;CCKR signaling map#P06959>cGK 1#P07149 LEPOC|Ensembl=ENSLOCG00000003366.1|UniProtKB=W5M6I1 W5M6I1 PTHR15288:SF5 DENN DOMAIN-CONTAINING PROTEIN 2 DENN DOMAIN-CONTAINING PROTEIN 2B molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000012241.1|UniProtKB=W5N350 W5N350 PTHR22883:SF23 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC6 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;protein targeting#GO:0006605;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008978.1|UniProtKB=W5MRC7 W5MRC7 PTHR24103:SF611 E3 UBIQUITIN-PROTEIN LIGASE TRIM BBOX AND DUF4200 DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010576.1|UniProtKB=W5MX48 W5MX48 PTHR12406:SF46 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;triacylglycerol lipase activity#GO:0004806;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 glycerolipid catabolic process#GO:0046503;triglyceride catabolic process#GO:0019433;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;homeostatic process#GO:0042592;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;cellular process#GO:0009987;lipid catabolic process#GO:0016042 intracellular organelle#GO:0043229;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000014345.1|UniProtKB=W5NAK7 W5NAK7 PTHR10869:SF249 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT TRANSMEMBRANE PROLYL 4-HYDROXYLASE regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of cell development#GO:0060284;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of myeloid cell differentiation#GO:0045637;regulation of cell differentiation#GO:0045595;regulation of hemopoiesis#GO:1903706 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005613.1|UniProtKB=W5MEI6 W5MEI6 PTHR11863:SF106 STEROL DESATURASE CHOLESTEROL 25-HYDROXYLASE-LIKE PROTEIN 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;secondary alcohol biosynthetic process#GO:1902653;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000013806.1|UniProtKB=W5N8S1 W5N8S1 PTHR22654:SF2 G PROTEIN PATHWAY SUPPRESSOR 2 G PROTEIN PATHWAY SUPPRESSOR 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017486.1|UniProtKB=W5NLT2 W5NLT2 PTHR12002:SF185 CLAUDIN CLAUDIN-2 cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000000222.1|UniProtKB=W5LVU0 W5LVU0 PTHR46888:SF16 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006629.1|UniProtKB=W5MHZ6 W5MHZ6 PTHR22961:SF14 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 3 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of ubiquitin-dependent protein catabolic process#GO:2000058 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000015145.1|UniProtKB=W5NDD5 W5NDD5 PTHR24174:SF3 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1B protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;localization#GO:0051179;ephrin receptor signaling pathway#GO:0048013;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cytosol#GO:0005829;presynapse#GO:0098793;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009549.1|UniProtKB=W5MTH4 W5MTH4 PTHR21377:SF1 PROTEIN FAM210B, MITOCHONDRIAL MITOCHONDRIAL INNER MEMBRANE SCAFFOLD 1 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000013274.1|UniProtKB=W5N6V0 W5N6V0 PTHR20208:SF10 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233 endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 LEPOC|Ensembl=ENSLOCG00000013993.1|UniProtKB=W5N9E2 W5N9E2 PTHR23327:SF4 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017066.1|UniProtKB=W5NKD2 W5NKD2 PTHR22872:SF15 BTK-BINDING PROTEIN-RELATED INHIBITOR OF BRUTON TYROSINE KINASE enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;enzyme inhibitor activity#GO:0004857 calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;calcium ion transmembrane import into cytosol#GO:0097553;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017511.1|UniProtKB=W5NLV7 W5NLV7 PTHR13469:SF8 HEXAMETHYLENE BISACETAMIDE INDUCIBLE 1 HEXIM P-TEFB COMPLEX SUBUNIT 1 enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase inhibitor activity#GO:0019210;binding#GO:0005488;nucleic acid binding#GO:0003676;molecular function inhibitor activity#GO:0140678;RNA binding#GO:0003723;enzyme regulator activity#GO:0030234;snRNA binding#GO:0017069 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000007561.1|UniProtKB=W5MLB7 W5MLB7 PTHR24356:SF438 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE GREATWALL protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011166.1|UniProtKB=W5MZB6 W5MZB6 PTHR47634:SF4 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SRSF PROTEIN KINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 response to stimulus#GO:0050896;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;signal transduction#GO:0007165;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;RNA splicing, via transesterification reactions#GO:0000375;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000003054.1|UniProtKB=W5M5D3 W5M5D3 PTHR22175:SF0 SMALL ACIDIC PROTEIN-RELATED SMALL ACIDIC PROTEIN nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000004394.1|UniProtKB=W5MA56 W5MA56 PTHR12802:SF9 SWI/SNF COMPLEX-RELATED SWI_SNF COMPLEX SUBUNIT SMARCC1 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ATPase complex#GO:1904949;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000007423.1|UniProtKB=W5MKU6 W5MKU6 PTHR16125:SF4 TRANSMEMBRANE PROTEIN 74 TRANSMEMBRANE PROTEIN 74B LEPOC|Ensembl=ENSLOCG00000002730.1|UniProtKB=W5M4A4 W5M4A4 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002187.1|UniProtKB=W5M2D6 W5M2D6 PTHR13582:SF0 M-PHASE PHOSPHOPROTEIN 6 M-PHASE PHOSPHOPROTEIN 6 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000015339.1|UniProtKB=W5NE16 W5NE16 PTHR12522:SF2 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN 703 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000008197.1|UniProtKB=W5MNJ3 W5MNJ3 PTHR13678:SF8 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37C intracellular protein transport#GO:0006886;macromolecule catabolic process#GO:0009057;protein targeting to membrane#GO:0006612;metabolic process#GO:0008152;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein targeting to vacuole#GO:0006623;establishment of protein localization to membrane#GO:0090150;protein transport#GO:0015031;cellular localization#GO:0051641;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;protein metabolic process#GO:0019538;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to vacuole#GO:0072665;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016722.1|UniProtKB=W5NJ50 W5NJ50 PTHR14731:SF1 BRAIN AND ACUTE LEUKEMIA CYTOPLASMIC PROTEIN BAALC BINDER OF MAP3K1 AND KLF4 B intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013940.1|UniProtKB=W5N977 W5N977 PTHR23049:SF75 MYOSIN REGULATORY LIGHT CHAIN 2 CALMODULIN-LIKE PROTEIN 4 myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000004813.1|UniProtKB=W5MBM1 W5MBM1 PTHR24161:SF123 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT AND SOCS BOX PROTEIN 10 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013765.1|UniProtKB=W5N8L5 W5N8L5 PTHR23412:SF19 STEREOCILIN RELATED STEREOCILIN cellular process#GO:0009987;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000014280.1|UniProtKB=W5NAC2 W5NAC2 PTHR15127:SF28 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN F binding#GO:0005488;protein binding#GO:0005515 LEPOC|Ensembl=ENSLOCG00000000370.1|UniProtKB=W5LW96 W5LW96 PTHR23320:SF128 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A-LIKE transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003611.1|UniProtKB=W5M7B9 W5M7B9 PTHR15907:SF26 DUF614 FAMILY PROTEIN-RELATED CORNIFELIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000006364.1|UniProtKB=W5MH19 W5MH19 PTHR12173:SF8 GDNF SUBFAMILY OF TGF-BETA FAMILY PERSEPHIN growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207;neurotrophic factor#PC00163 LEPOC|Ensembl=ENSLOCG00000013350.1|UniProtKB=W5N741 W5N741 PTHR12015:SF198 SMALL INDUCIBLE CYTOKINE A INTERLEUKIN-8 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125 cell migration#GO:0016477;response to other organism#GO:0051707;immune response#GO:0006955;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;leukocyte migration#GO:0050900;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;response to bacterium#GO:0009617;chemotaxis#GO:0006935;inflammatory response#GO:0006954;taxis#GO:0042330;neutrophil migration#GO:1990266;response to chemical#GO:0042221;granulocyte migration#GO:0097530;cellular response to lipid#GO:0071396;defense response to other organism#GO:0098542;response to lipid#GO:0033993;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;neutrophil chemotaxis#GO:0030593;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to molecule of bacterial origin#GO:0002237;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 CCKR signaling map#P06959>IL8#G07296;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856;CCKR signaling map#P06959>IL8#G07001;CCKR signaling map#P06959>IL8#P07136;Interleukin signaling pathway#P00036>Interleukin#P00970 LEPOC|Ensembl=ENSLOCG00000004857.1|UniProtKB=W5MBU1 W5MBU1 PTHR11474:SF4 TYROSINASE FAMILY MEMBER L-DOPACHROME TAUTOMERASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 melanin biosynthetic process#GO:0042438;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;forebrain development#GO:0030900;positive regulation of nervous system development#GO:0051962;central nervous system development#GO:0007417;cell differentiation#GO:0030154;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;phenol-containing compound metabolic process#GO:0018958;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of cell differentiation#GO:0045597;secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;head development#GO:0060322;nervous system development#GO:0007399;developmental pigmentation#GO:0048066;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;phenol-containing compound biosynthetic process#GO:0046189;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell population proliferation#GO:0042127;pigmentation#GO:0043473;cell population proliferation#GO:0008283;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell division#GO:0051301;regulation of neurogenesis#GO:0050767;neurogenesis#GO:0022008;secondary metabolic process#GO:0019748;cellular developmental process#GO:0048869;regulation of cell differentiation#GO:0045595;pigment biosynthetic process#GO:0046148;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;biological regulation#GO:0065007;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;pigment metabolic process#GO:0042440 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;melanosome#GO:0042470;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000015539.1|UniProtKB=W5NES4 W5NES4 PTHR13720:SF52 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 6 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000009172.1|UniProtKB=W5MS28 W5MS28 PTHR13547:SF23 RIBONUCLEASE P MITOCHONDRIAL RIBONUCLEASE P CATALYTIC SUBUNIT hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;ribonuclease P activity#GO:0004526;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787 RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular protein-containing complex#GO:0140535;endonuclease complex#GO:1905348 LEPOC|Ensembl=ENSLOCG00000011786.1|UniProtKB=W5N1J1 W5N1J1 PTHR31882:SF15 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 1 cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;cellular response to lipopolysaccharide#GO:0071222;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to lipopolysaccharide#GO:0032496;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;negative regulation of biological process#GO:0048519;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to molecule of bacterial origin#GO:0071219;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;response to external biotic stimulus#GO:0043207;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cellular process#GO:0050794;response to bacterium#GO:0009617;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 LEPOC|Ensembl=ENSLOCG00000000101.1|UniProtKB=W5LVF9 W5LVF9 PTHR11339:SF289 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED VWFD DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000002342.1|UniProtKB=W5M2Y2 W5M2Y2 PTHR14409:SF0 MANNOSIDASE, BETA A, LYSOSOMAL-LIKE, MANBAL PROTEIN PROTEIN MANBAL LEPOC|Ensembl=ENSLOCG00000016375.1|UniProtKB=W5NHV9 W5NHV9 PTHR45716:SF1 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887 membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000013986.1|UniProtKB=W5N9D0 W5N9D0 PTHR46356:SF1 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015567.1|UniProtKB=W5NEV7 W5NEV7 PTHR11566:SF50 DYNAMIN DYNAMIN-1-LIKE PROTEIN ISOFORM X1 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;GTPase activity#GO:0003924;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;protein binding#GO:0005515;tubulin binding#GO:0015631;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111 mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;mitochondrion localization#GO:0051646;organelle localization#GO:0051640;peroxisome organization#GO:0007031 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008583.1|UniProtKB=W5MPY0 W5MPY0 PTHR11267:SF88 T-BOX PROTEIN-RELATED T-BOX BRAIN PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;neuron fate commitment#GO:0048663;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of cell projection organization#GO:0031344;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;forebrain development#GO:0030900;regulation of biological process#GO:0050789;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;head development#GO:0060322;nervous system development#GO:0007399;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;cell fate specification#GO:0001708 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 LEPOC|Ensembl=ENSLOCG00000012835.1|UniProtKB=W5N587 W5N587 PTHR24027:SF290 CADHERIN-23 CADHERIN-10 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell adhesion#GO:0007155;synapse organization#GO:0050808;anatomical structure development#GO:0048856;synaptic membrane adhesion#GO:0099560;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell migration#GO:0016477;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000005220.1|UniProtKB=W5MD23 W5MD23 PTHR12812:SF3 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE 3 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000008887.1|UniProtKB=W5MR14 W5MR14 PTHR11827:SF96 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 9 solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000010628.1|UniProtKB=W5MXA6 W5MXA6 PTHR11515:SF5 GLYCOPROTEIN HORMONE BETA CHAIN THYROTROPIN SUBUNIT BETA hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Thyrotropin#P04588;Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585 LEPOC|Ensembl=ENSLOCG00000013880.1|UniProtKB=W5N907 W5N907 PTHR16716:SF3 CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL metabolite interconversion enzyme#PC00262;oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010760.1|UniProtKB=W5MXS2 W5MXS2 PTHR13312:SF0 HIV-INDUCED PROTEIN-7-LIKE PROTEASE UBIQUITIN THIOESTERASE OTU1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to unfolded protein#GO:0006986;cell communication#GO:0007154;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000000877.1|UniProtKB=W5LXX5 W5LXX5 PTHR46102:SF3 AXIN AXIN-1 identical protein binding#GO:0042802;ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389;protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 anatomical structure development#GO:0048856;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of catabolic process#GO:0009896;cellular developmental process#GO:0048869;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;positive regulation of proteasomal protein catabolic process#GO:1901800;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of Wnt signaling pathway#GO:0030111;cell development#GO:0048468;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of protein metabolic process#GO:0051246;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>Axin#P01429;Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000012110.1|UniProtKB=W5N2P1 W5N2P1 PTHR23343:SF117 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 1-LIKE binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198 biological regulation#GO:0065007;fertilization#GO:0009566;reproductive process#GO:0022414;regulation of reproductive process#GO:2000241;multicellular organismal process#GO:0032501;regulation of biological process#GO:0050789;cellular process#GO:0009987;negative regulation of biological process#GO:0048519;single fertilization#GO:0007338;cell-cell recognition#GO:0009988;binding of sperm to zona pellucida#GO:0007339;sexual reproduction#GO:0019953;cell activation#GO:0001775;cell recognition#GO:0008037;sperm-egg recognition#GO:0035036 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012145.1|UniProtKB=W5N2T2 W5N2T2 PTHR45776:SF5 MIP04163P TRANSCRIPTION FACTOR EB DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;vacuole organization#GO:0007033;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;lysosome organization#GO:0007040;regulation of primary metabolic process#GO:0080090;positive regulation of autophagy#GO:0010508;organelle organization#GO:0006996;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;lytic vacuole organization#GO:0080171;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000009540.1|UniProtKB=W5MTE9 W5MTE9 PTHR12189:SF2 MRNA GUANINE-7- METHYLTRANSFERASE MRNA CAP GUANINE-N(7) METHYLTRANSFERASE RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000016514.1|UniProtKB=W5NID9 W5NID9 PTHR46987:SF1 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-3 frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000000009.1|UniProtKB=W5LV53 W5LV53 PTHR35084:SF1 TCF3 FUSION PARTNER TCF3 FUSION PARTNER nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;cell communication#GO:0007154;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;apoptotic signaling pathway#GO:0097190 SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;Ino80 complex#GO:0031011;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000002908.1|UniProtKB=W5M4X1 W5M4X1 PTHR23347:SF5 COLORECTAL MUTANT CANCER PROTEIN MCC PROTEIN -RELATED HARMONIN-BINDING PROTEIN USHBP1 LEPOC|Ensembl=ENSLOCG00000013770.1|UniProtKB=W5N8N1 W5N8N1 PTHR43563:SF23 AMINE OXIDASE AMINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;amine catabolic process#GO:0009310;serotonin metabolic process#GO:0042428;amine metabolic process#GO:0009308;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;phenol-containing compound metabolic process#GO:0018958;catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000014181.1|UniProtKB=W5NA09 W5NA09 PTHR16148:SF11 NF-KAPPA-B-REPRESSING FACTOR-RELATED CDKN2A-INTERACTING PROTEIN regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000005768.1|UniProtKB=W5MF21 W5MF21 PTHR10226:SF3 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN 11 protein kinase A binding#GO:0051018;binding#GO:0005488;protein binding#GO:0005515 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;macromolecule localization#GO:0033036;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;localization#GO:0051179;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;intracellular protein localization#GO:0008104;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018206.1|UniProtKB=W5NNU8 W5NNU8 PTHR23516:SF1 SAM (S-ADENOSYL METHIONINE) TRANSPORTER SOLUTE CARRIER FAMILY 61 MEMBER 1 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006858.1|UniProtKB=W5MIT8 W5MIT8 PTHR24031:SF68 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX51 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000017060.1|UniProtKB=W5NKC2 W5NKC2 ELOVL4 PTHR11157:SF126 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 4 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000008641.1|UniProtKB=W5MQ47 W5MQ47 PTHR46498:SF1 GTP-BINDING PROTEIN 8 GTP-BINDING PROTEIN 8 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000003562.1|UniProtKB=W5M757 W5M757 PTHR13044:SF3 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-5 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000001930.1|UniProtKB=W5M1H4 W5M1H4 PTHR31885:SF6 GH04784P LYSOPLASMALOGENASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000018347.1|UniProtKB=W5NP89 W5NP89 PTHR46948:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P38 RIBONUCLEASE P PROTEIN SUBUNIT P38 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000017702.1|UniProtKB=W5NME8 W5NME8 PTHR46617:SF5 FORKHEAD BOX PROTEIN G1 FORKHEAD BOX PROTEIN G1 sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000001278.1|UniProtKB=W5LZA4 W5LZA4 PTHR46164:SF1 ATF6, ISOFORM C CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-6 ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;response to unfolded protein#GO:0006986;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 Apoptosis signaling pathway#P00006>ATF#P00302 LEPOC|Ensembl=ENSLOCG00000007077.1|UniProtKB=W5MJL7 W5MJL7 PTHR47970:SF41 KINESIN-LIKE PROTEIN KIF11 KINESIN FAMILY MEMBER 11 isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;microtubule motor activity#GO:0003777;plus-end-directed microtubule motor activity#GO:0008574;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544 mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;nuclear division#GO:0000280;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059 organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;spindle#GO:0005819;cytoskeleton#GO:0005856 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000012469.1|UniProtKB=W5N3Z7 W5N3Z7 PTHR43391:SF15 RETINOL DEHYDROGENASE-RELATED 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;hormone biosynthetic process#GO:0042446;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;steroid biosynthetic process#GO:0006694;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 LEPOC|Ensembl=ENSLOCG00000000353.1|UniProtKB=W5LW78 W5LW78 PTHR46105:SF12 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 8A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013622.1|UniProtKB=W5N837 W5N837 PTHR24251:SF27 OVOCHYMASE-RELATED NEUROPILIN AND TOLLOID-LIKE PROTEIN 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 protein localization to cell periphery#GO:1990778;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;protein localization to synapse#GO:0035418;intracellular protein localization#GO:0008104;regulation of localization#GO:0032879;macromolecule localization#GO:0033036;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;biological regulation#GO:0065007;protein localization to cell junction#GO:1902414;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794 postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016635.1|UniProtKB=W5NIT9 W5NIT9 PTHR34174:SF1 HYDROLETHALUS SYNDROME PROTEIN 1 CENTRIOLAR AND CILIOGENESIS-ASSOCIATED PROTEIN HYLS1 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000004044.1|UniProtKB=W5M8W7 W5M8W7 PTHR23003:SF62 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE_ARGININE (SR)-TYPE SHUTTLING MRNA BINDING PROTEIN NPL3 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000014288.1|UniProtKB=W5NAD0 W5NAD0 PTHR48071:SF15 SRCR DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR FAMILY 12 SUBFAMILY J MEMBER 2 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008924.1|UniProtKB=W5MR57 W5MR57 PTHR24200:SF14 TOUCAN, ISOFORM A MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR CANDIDATE 2 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000000160.1|UniProtKB=W5LVM2 W5LVM2 PTHR45755:SF6 FAMILY NOT NAMED ZINC TRANSPORTER 7 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;zinc ion transmembrane transport#GO:0071577;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 endomembrane system#GO:0012505;Golgi cisterna#GO:0031985;cytoplasm#GO:0005737;Golgi cis cisterna#GO:0000137;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;Golgi stack#GO:0005795;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013260.1|UniProtKB=W5N6S6 W5N6S6 PTHR15907:SF30 DUF614 FAMILY PROTEIN-RELATED PLAC8 ONZIN RELATED PROTEIN 5 ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000004141.1|UniProtKB=W5M992 W5M992 PTHR15193:SF1 CD83 ANTIGEN CD83 ANTIGEN LEPOC|Ensembl=ENSLOCG00000005864.1|UniProtKB=W5MFB9 W5MFB9 PTHR16833:SF0 DNA DAMAGE-INDUCIBLE TRANSCRIPT 3 DDIT3 DNA DAMAGE-INDUCIBLE TRANSCRIPT 3 PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to biotic stimulus#GO:0071216;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;response to endoplasmic reticulum stress#GO:0034976;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;apoptotic signaling pathway#GO:0097190;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;negative regulation of DNA-templated transcription#GO:0045892;intrinsic apoptotic signaling pathway#GO:0097193;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;response to biotic stimulus#GO:0009607;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 Oxidative stress response#P00046>CHOP#P01130 LEPOC|Ensembl=ENSLOCG00000012442.1|UniProtKB=W5N3V5 W5N3V5 PTHR35453:SF1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 Golgi apparatus#GO:0005794;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000001184.1|UniProtKB=W5LYY4 W5LYY4 PTHR16007:SF59 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B LEPOC|Ensembl=ENSLOCG00000013860.1|UniProtKB=W5N8Y4 W5N8Y4 PTHR46269:SF1 EPIPHYCAN-RELATED MIMECAN bone development#GO:0060348;tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cartilage development#GO:0051216;connective tissue development#GO:0061448;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;animal organ development#GO:0048513;anatomical structure development#GO:0048856 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013374.1|UniProtKB=W5N7A7 W5N7A7 PTHR13140:SF273 MYOSIN UNCONVENTIONAL MYOSIN-VA isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000015055.1|UniProtKB=W5ND18 W5ND18 PTHR13964:SF25 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5A double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000005437.1|UniProtKB=W5MDU3 W5MDU3 PTHR12461:SF108 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of Notch signaling pathway#GO:0045746;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signaling#GO:0023057;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014670.1|UniProtKB=W5NBQ5 W5NBQ5 PTHR24351:SF192 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to nitrogen compound#GO:1901698;response to peptide hormone#GO:0043434 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016046.1|UniProtKB=W5NGK6 W5NGK6 AFTPH PTHR16156:SF10 AFTIPHILIN A-RELATED AFTIPHILIN A protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 organelle membrane#GO:0031090;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane coat#GO:0030117;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;membrane protein complex#GO:0098796;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;vesicle coat#GO:0030120;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;trans-Golgi network membrane#GO:0032588;cytoplasmic vesicle membrane#GO:0030659;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular organelle#GO:0043229;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000016442.1|UniProtKB=W5NI48 W5NI48 PTHR11848:SF322 TGF-BETA FAMILY BMP2-RELATED signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;heart morphogenesis#GO:0003007;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;response to growth factor#GO:0070848;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000000253.1|UniProtKB=W5LVX0 W5LVX0 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 519 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000003101.1|UniProtKB=W5M5K7 W5M5K7 PTHR11105:SF0 CITRATE LYASE SUBUNIT BETA-RELATED CITRAMALYL-COA LYASE, MITOCHONDRIAL lyase activity#GO:0016829;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 lyase#PC00144 Pyruvate metabolism#P02772>Citrate Lyase#P03137 LEPOC|Ensembl=ENSLOCG00000017389.1|UniProtKB=W5NLI5 W5NLI5 PTHR11829:SF411 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000018058.1|UniProtKB=W5NNF0 W5NNF0 PTHR37361:SF4 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 9 FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012696.1|UniProtKB=W5N4R3 W5N4R3 PTHR16435:SF5 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6 SPERMATOGENESIS ASSOCIATED 6-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000016189.1|UniProtKB=W5NH51 W5NH51 PTHR10188:SF41 L-ASPARAGINASE ISOASPARTYL PEPTIDASE_L-ASPARAGINASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824;amidase activity#GO:0004040;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009368.1|UniProtKB=W5MSR8 W5MSR8 PTHR11599:SF10 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-3 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;proteasome complex#GO:0000502;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000011984.1|UniProtKB=W5N2A4 W5N2A4 PTHR10075:SF113 BASIGIN RELATED NEUROFASCIN cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000006504.1|UniProtKB=W5MHM2 W5MHM2 PTHR14074:SF16 HELICASE WITH DEATH DOMAIN-RELATED ANTIVIRAL INNATE IMMUNE RESPONSE RECEPTOR RIG-I single-stranded RNA binding#GO:0003727;zinc ion binding#GO:0008270;RNA binding#GO:0003723;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;transition metal ion binding#GO:0046914 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008929.1|UniProtKB=W5MR90 W5MR90 PTHR47335:SF1 UNCONVENTIONAL MYOSIN-XVI UNCONVENTIONAL MYOSIN-XVI cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987 organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;actin cytoskeleton#GO:0015629;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;perinuclear region of cytoplasm#GO:0048471;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;myosin complex#GO:0016459;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000014882.1|UniProtKB=W5NCG7 W5NCG7 PTHR45799:SF8 RETICULON-LIKE PROTEIN RETICULON endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endoplasmic reticulum tubular network organization#GO:0071786;endoplasmic reticulum membrane organization#GO:0090158;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011471.1|UniProtKB=W5N0D5 W5N0D5 PTHR21321:SF1 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP40 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA metabolic process#GO:0016073;rRNA processing#GO:0006364;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;snRNA 3'-end processing#GO:0034472;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;maturation of 5.8S rRNA#GO:0000460;negative regulation of gene expression#GO:0010629;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000012756.1|UniProtKB=W5N4Z1 W5N4Z1 PTHR12586:SF1 CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009526.1|UniProtKB=W5MTD0 W5MTD0 PTHR12052:SF4 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4B RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008449.1|UniProtKB=W5MPJ4 W5MPJ4 PTHR22050:SF1 RW1 PROTEIN HOMOLOG TRANSMEMBRANE PROTEIN 131 biosynthetic process#GO:0009058;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000011813.1|UniProtKB=W5N1L9 W5N1L9 PTHR10671:SF40 EPITHELIAL MEMBRANE PROTEIN-RELATED GERM CELL-SPECIFIC GENE 1-LIKE PROTEIN 2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000001848.1|UniProtKB=W5M181 W5M181 PTHR21553:SF36 ALMS1-RELATED CENTROSOME-ASSOCIATED PROTEIN ALMS1 ISOFORM X1 regulation of microtubule-based process#GO:0032886;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115;regulation of organelle organization#GO:0033043;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoplasm#GO:0005737;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000012946.1|UniProtKB=W5N5N0 W5N5N0 PTHR10489:SF922 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 2 ISOFORM X1-RELATED immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;locomotion#GO:0040011;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015194.1|UniProtKB=W5NDJ2 W5NDJ2 PTHR11101:SF46 PHOSPHATE TRANSPORTER SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 1 phosphate transmembrane transporter activity#GO:0005315;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 transport#GO:0006810;cellular process#GO:0009987;phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002595.1|UniProtKB=W5M3U3 W5M3U3 PTHR46186:SF13 CYSTATIN SI:BUSM1-57F23.1 enzyme regulator activity#GO:0030234;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 extracellular region#GO:0005576;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000011174.1|UniProtKB=W5MZC6 W5MZC6 PTHR11311:SF8 SPONDIN THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 7A cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012286.1|UniProtKB=W5N3B8 W5N3B8 PTHR12563:SF16 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;triglyceride biosynthetic process#GO:0019432;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000004955.1|UniProtKB=W5MC47 W5MC47 PTHR45775:SF3 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN RAD guanyl nucleotide binding#GO:0019001;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;calcium channel regulator activity#GO:0005246;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;transporter regulator activity#GO:0141108;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000016329.1|UniProtKB=W5NHQ1 W5NHQ1 PTHR43612:SF3 TRIFUNCTIONAL ENZYME SUBUNIT ALPHA TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000000427.1|UniProtKB=W5LWG1 W5LWG1 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cell communication#GO:0007154;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009394.1|UniProtKB=W5MSU4 W5MSU4 PTHR14557:SF3 PROTEIN C7ORF21 TRANSMEMBRANE AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN 1 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056 LEPOC|Ensembl=ENSLOCG00000003917.1|UniProtKB=W5M8H0 W5M8H0 PTHR11848:SF157 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 2 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;positive regulation of epithelial cell proliferation#GO:0050679;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000001849.1|UniProtKB=W5M186 W5M186 PTHR12555:SF13 UBIQUITIN FUSION DEGRADATON PROTEIN 1 UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011496.1|UniProtKB=W5N0G8 W5N0G8 PTHR24237:SF43 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 141-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013861.1|UniProtKB=W5N8Y5 W5N8Y5 PTHR14559:SF1 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 14 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003377.1|UniProtKB=W5M6J6 W5M6J6 PTHR14594:SF1 CENTROSOMAL PROTEIN OF 70 KDA CENTROSOMAL PROTEIN OF 70 KDA cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001404.1|UniProtKB=W5LZP4 W5LZP4 PTHR19325:SF493 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING E-SELECTIN carbohydrate binding#GO:0030246;oligosaccharide binding#GO:0070492;carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;binding#GO:0005488;small molecule binding#GO:0036094;organic acid binding#GO:0043177 response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;cell migration#GO:0016477;cell motility#GO:0048870;leukocyte cell-cell adhesion#GO:0007159;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;response to peptide#GO:1901652;cell adhesion#GO:0007155;immune system process#GO:0002376;leukocyte migration#GO:0050900 external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;side of membrane#GO:0098552;membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000006428.1|UniProtKB=W5MHA8 W5MHA8 PTHR12628:SF6 POLYCOMB-LIKE TRANSCRIPTION FACTOR PHD FINGER PROTEIN 19 chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000000707.1|UniProtKB=W5LXC8 W5LXC8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006359.1|UniProtKB=W5MH29 W5MH29 PTHR31671:SF0 DIABETES AND OBESITY REGULATED, ISOFORM G TUMOR PROTEIN P53-INDUCIBLE NUCLEAR PROTEIN 1 transcription coactivator activity#GO:0003713;protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674;transcription regulator activity#GO:0140110 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;macroautophagy#GO:0016236;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;organelle assembly#GO:0070925;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;vacuole organization#GO:0007033;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;positive regulation of biological process#GO:0048518;autophagy#GO:0006914;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;process utilizing autophagic mechanism#GO:0061919 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;autophagosome#GO:0005776;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009089.1|UniProtKB=W5MRS4 W5MRS4 PTHR31139:SF3 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG LIX1-LIKE PROTEIN cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000003308.1|UniProtKB=W5M6A0 W5M6A0 PTHR46500:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 221 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 221 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 9+2 motile cilium#GO:0097729;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004499.1|UniProtKB=W5MAH2 W5MAH2 PTHR46093:SF16 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5 MULTIPLE EGF-LIKE-DOMAINS 8 LEPOC|Ensembl=ENSLOCG00000014070.1|UniProtKB=W5N9N0 W5N9N0 PTHR45629:SF13 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000008772.1|UniProtKB=W5MQL9 W5MQL9 PTHR23325:SF1 SERUM RESPONSE FACTOR-BINDING SERUM RESPONSE FACTOR-BINDING PROTEIN 1 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 ribonucleoprotein complex#GO:1990904;90S preribosome#GO:0030686;preribosome#GO:0030684;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015008.1|UniProtKB=W5NCX1 W5NCX1 PTHR11782:SF29 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 4 nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;ribonucleoside diphosphate metabolic process#GO:0009185;nucleoside diphosphate catabolic process#GO:0009134;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleoside diphosphate metabolic process#GO:0009132;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000010852.1|UniProtKB=W5MY44 W5MY44 PTHR16198:SF2 INO80 COMPLEX SUBUNIT D INO80 COMPLEX SUBUNIT D organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000014647.1|UniProtKB=W5NBL9 W5NBL9 PTHR13161:SF4 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT CLK4-ASSOCIATING SERINE_ARGININE RICH PROTEIN alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000008617.1|UniProtKB=W5MQ18 W5MQ18 RPS3A PTHR11830:SF0 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000017490.1|UniProtKB=W5NLT6 W5NLT6 PTHR19957:SF447 SYNTAXIN PROVISIONAL ORTHOLOG OF SYNTAXIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 protein transport#GO:0015031;secretion by cell#GO:0032940;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;export from cell#GO:0140352;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;vesicle organization#GO:0016050;exocytosis#GO:0006887;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;organelle organization#GO:0006996;membrane fusion#GO:0061025;macromolecule localization#GO:0033036 cytoplasm#GO:0005737;plasma membrane#GO:0005886;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000003580.1|UniProtKB=W5M794 W5M794 PTHR16294:SF7 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN DOMAIN-CONTAINING PROTEIN 2 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 LEPOC|Ensembl=ENSLOCG00000012866.1|UniProtKB=W5N5D2 W5N5D2 PTHR48071:SF4 SRCR DOMAIN-CONTAINING PROTEIN NEUROTRYPSIN LEPOC|Ensembl=ENSLOCG00000001799.1|UniProtKB=W5M126 W5M126 PTHR14469:SF0 SARCOMA ANTIGEN NY-SAR-23 FAMILY WITH SEQUENCE SIMILARITY 113 LEPOC|Ensembl=ENSLOCG00000010502.1|UniProtKB=W5MWW8 W5MWW8 PTHR24347:SF197 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1 protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;regulation of synapse structure or activity#GO:0050803;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of synapse organization#GO:0050807 postsynaptic density#GO:0014069;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;postsynapse#GO:0098794;cytoplasm#GO:0005737;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000000220.1|UniProtKB=W5LVT9 W5LVT9 PTHR12107:SF12 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-7 SUBUNIT monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;voltage-gated calcium channel activity#GO:0005245;channel regulator activity#GO:0016247;channel activity#GO:0015267;transporter regulator activity#GO:0141108;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;system process#GO:0003008;transmission of nerve impulse#GO:0019226;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;localization within membrane#GO:0051668;regulation of signaling#GO:0023051;nervous system process#GO:0050877;positive regulation of synaptic transmission#GO:0050806;regulation of biological quality#GO:0065008;localization#GO:0051179;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;regulation of biological process#GO:0050789;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;cell junction#GO:0030054 voltage-gated ion channel#PC00241;ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001208.1|UniProtKB=W5LZ02 W5LZ02 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune system process#GO:0002376;cell communication#GO:0007154;immune response#GO:0006955;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017667.1|UniProtKB=W5NMB3 W5NMB3 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002986.1|UniProtKB=W5M563 W5M563 PTHR24208:SF121 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX6 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;forebrain development#GO:0030900;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;head development#GO:0060322;nervous system development#GO:0007399;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009508.1|UniProtKB=W5MTA8 W5MTA8 PTHR23235:SF132 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 9 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013320.1|UniProtKB=W5N713 W5N713 PTHR15583:SF14 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR D cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003515.1|UniProtKB=W5M701 W5M701 PTHR46200:SF1 GATOR COMPLEX PROTEIN WDR24 GATOR2 COMPLEX PROTEIN WDR24 regulation of macroautophagy#GO:0016241;cellular response to amino acid starvation#GO:0034198;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;positive regulation of macroautophagy#GO:0016239;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;positive regulation of TORC1 signaling#GO:1904263;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;positive regulation of TOR signaling#GO:0032008;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;Seh1-associated complex#GO:0035859;vacuolar membrane#GO:0005774;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000017281.1|UniProtKB=W5NL68 W5NL68 PTHR10574:SF291 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-2 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000007858.1|UniProtKB=W5MMD0 W5MMD0 PTHR21041:SF17 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE DCST1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell-cell recognition#GO:0009988;sperm-egg recognition#GO:0035036;cell recognition#GO:0008037;sexual reproduction#GO:0019953;reproductive process#GO:0022414;fertilization#GO:0009566;single fertilization#GO:0007338;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669 LEPOC|Ensembl=ENSLOCG00000003461.1|UniProtKB=W5M6V3 W5M6V3 PTHR13402:SF13 RGPR-RELATED PROTEIN TRANSPORT PROTEIN SEC16A intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507 LEPOC|Ensembl=ENSLOCG00000004254.1|UniProtKB=W5M9M7 W5M9M7 PTHR45782:SF4 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 ribosomal large subunit assembly#GO:0000027;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mitochondrial ribosome assembly#GO:0061668;membraneless organelle assembly#GO:0140694;mitochondrial large ribosomal subunit assembly#GO:1902775;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;protein-RNA complex assembly#GO:0022618 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000012243.1|UniProtKB=W5N345 W5N345 PTHR24058:SF35 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 protein-containing complex disassembly#GO:0032984;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cell cycle#GO:0045787;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of cell cycle G2/M phase transition#GO:1902749;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001212.1|UniProtKB=W5LZ09 W5LZ09 PTHR35671:SF1 PROTEIN TOPAZ1 PROTEIN TOPAZ1 male gamete generation#GO:0048232;gamete generation#GO:0007276;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;cellular process#GO:0009987;cell division#GO:0051301;multicellular organismal reproductive process#GO:0048609;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;developmental process#GO:0032502 LEPOC|Ensembl=ENSLOCG00000009065.1|UniProtKB=W5MRR7 W5MRR7 PTHR23083:SF365 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT PROTEIN 7B intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;localization#GO:0051179;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641;phosphatidylinositol phosphate biosynthetic process#GO:0046854;localization within membrane#GO:0051668;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010039.1|UniProtKB=W5MV67 W5MV67 PTHR45646:SF4 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017236.1|UniProtKB=W5NL09 W5NL09 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;nucleus#GO:0005634;site of double-strand break#GO:0035861;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000013707.1|UniProtKB=W5N8E2 W5N8E2 PTHR16196:SF0 CELL CYCLE CONTROL PROTEIN CWF25 PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000013745.1|UniProtKB=W5N8J2 W5N8J2 PTHR43461:SF1 TRANSMEMBRANE PROTEIN 256 TRANSMEMBRANE PROTEIN 256 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000002475.1|UniProtKB=W5M3F9 W5M3F9 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009725.1|UniProtKB=W5MU26 W5MU26 PTHR12604:SF4 KU AUTOANTIGEN DNA HELICASE DNA REPAIR PROTEIN KU80 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690 cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;telomere organization#GO:0032200;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;double-strand break repair via nonhomologous end joining#GO:0006303;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA helicase#PC00011 LEPOC|Ensembl=ENSLOCG00000012084.1|UniProtKB=W5N2L5 W5N2L5 PTHR12752:SF5 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 6 LEPOC|Ensembl=ENSLOCG00000014693.1|UniProtKB=W5NBT0 W5NBT0 PTHR10827:SF78 RETICULOCALBIN RETICULOCALBIN-2 metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000017255.1|UniProtKB=W5NL34 W5NL34 PTHR10015:SF185 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000007076.1|UniProtKB=W5MJK7 W5MJK7 PTHR15298:SF17 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000010964.1|UniProtKB=W5MYK7 W5MYK7 PTHR22802:SF394 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR 2 pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010366.1|UniProtKB=W5MWE1 W5MWE1 PTHR33444:SF7 SI:DKEY-19B23.12-RELATED TRANSMEMBRANE PROTEIN 272 LEPOC|Ensembl=ENSLOCG00000001789.1|UniProtKB=W5M127 W5M127 PTHR46143:SF1 CALPAIN-7 CALPAIN-7 cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000000802.1|UniProtKB=W5LXR6 W5LXR6 PTHR43605:SF17 ACYL-COENZYME A SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;acyltransferase activity#GO:0016746 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 metabolite interconversion enzyme#PC00262;ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000016021.1|UniProtKB=W5NGI0 W5NGI0 PTHR22988:SF31 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE MRCK ALPHA catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012396.1|UniProtKB=W5N3Q6 W5N3Q6 PTHR35259:SF1 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000004849.1|UniProtKB=W5MBS6 W5MBS6 PTHR12784:SF6 STEERIN NEURON NAVIGATOR 2 system development#GO:0048731;nervous system development#GO:0007399;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 LEPOC|Ensembl=ENSLOCG00000015639.1|UniProtKB=W5NF43 W5NF43 PTHR11963:SF48 LEUCINE AMINOPEPTIDASE-RELATED DIPEPTIDASE B, ISOFORM A hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017065.1|UniProtKB=W5NKC9 W5NKC9 PTHR12974:SF25 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5A adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311 LEPOC|Ensembl=ENSLOCG00000001572.1|UniProtKB=W5M0A3 W5M0A3 PTHR11635:SF126 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I-BETA REGULATORY SUBUNIT small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;nucleotide binding#GO:0000166;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;kinase binding#GO:0019900;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase inhibitor activity#GO:0019210;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;protein kinase A binding#GO:0051018;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Hedgehog signaling pathway#P00025>PKA#P00682;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Gonadotropin-releasing hormone receptor pathway#P06664>PKA#P06782;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Endothelin signaling pathway#P00019>PKA#P00570;GABA-B receptor II signaling#P05731>PKA#P05752;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050 LEPOC|Ensembl=ENSLOCG00000009266.1|UniProtKB=W5MSE5 W5MSE5 PTHR13774:SF17 PHENAZINE BIOSYNTHESIS PROTEIN PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000016561.1|UniProtKB=W5NIJ3 W5NIJ3 PTHR23043:SF22 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA SINGLE-MINDED HOMOLOG 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000007040.1|UniProtKB=W5MJF8 W5MJF8 PTHR15427:SF55 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER ADIPONECTIN ISOFORM X1-RELATED signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013240.1|UniProtKB=W5N6Q1 W5N6Q1 PTHR10603:SF3 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN RNA-BINDING PROTEIN FXR2 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 regulation of cellular process#GO:0050794;RNA localization#GO:0006403;RNA transport#GO:0050658;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound transport#GO:0015931;regulation of cell communication#GO:0010646;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;establishment of RNA localization#GO:0051236;modulation of chemical synaptic transmission#GO:0050804;mRNA transport#GO:0051028;regulation of neurogenesis#GO:0050767;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;nucleic acid transport#GO:0050657;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;regulation of RNA metabolic process#GO:0051252;positive regulation of translation#GO:0045727;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;nitrogen compound transport#GO:0071705;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;regulation of neuronal synaptic plasticity#GO:0048168;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;post-transcriptional regulation of gene expression#GO:0010608;regulation of synaptic plasticity#GO:0048167;transport#GO:0006810;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;positive regulation of nervous system development#GO:0051962;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;regulation of trans-synaptic signaling#GO:0099177;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;regulation of mRNA metabolic process#GO:1903311;positive regulation of cell differentiation#GO:0045597 organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;neuron projection#GO:0043005;nucleus#GO:0005634;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494 translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000005476.1|UniProtKB=W5ME08 W5ME08 PTHR13817:SF80 TITIN INACTIVE TYROSINE-PROTEIN KINASE 7 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000015272.1|UniProtKB=W5NDT5 W5NDT5 PTHR11455:SF16 CRYPTOCHROME CRYPTOCHROME-1 heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;nucleotide binding#GO:0000166;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA binding#GO:0003677;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;deoxyribodipyrimidine photo-lyase activity#GO:0003904;nucleic acid binding#GO:0003676 negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;circadian regulation of gene expression#GO:0032922;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;negative regulation of DNA-templated transcription#GO:0045892;rhythmic process#GO:0048511;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to radiation#GO:0009314;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;photoperiodism#GO:0009648;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to light stimulus#GO:0009416;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA photolyase#PC00014 Circadian clock system#P00015>cry#G01497;Circadian clock system#P00015>cry#G01501;Circadian clock system#P00015>Cry#P00505 LEPOC|Ensembl=ENSLOCG00000011913.1|UniProtKB=W5N1Y8 W5N1Y8 PTHR10903:SF206 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000009730.1|UniProtKB=W5MU21 W5MU21 PTHR12056:SF4 DNA-DIRECTED RNA POLYMERASES I, II, AND III DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098 intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 LEPOC|Ensembl=ENSLOCG00000014584.1|UniProtKB=W5NBE3 W5NBE3 PTHR45973:SF8 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 49 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000000843.1|UniProtKB=W5LXT7 W5LXT7 PTHR23291:SF35 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 3 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 negative regulation of signal transduction#GO:0009968;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;negative regulation of neuron apoptotic process#GO:0043524;regulation of apoptotic process#GO:0042981;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;response to unfolded protein#GO:0006986;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of extrinsic apoptotic signaling pathway#GO:2001236;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to topologically incorrect protein#GO:0035967;regulation of apoptotic signaling pathway#GO:2001233;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004797.1|UniProtKB=W5MBN6 W5MBN6 PTHR22427:SF2 GH15728P BTB_POZ DOMAIN-CONTAINING PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000010113.1|UniProtKB=W5MVG5 W5MVG5 PTHR10953:SF6 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity#GO:0016874;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000008019.1|UniProtKB=W5MMY0 W5MMY0 PTHR10559:SF18 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR TRANSCOBALAMIN II tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;binding#GO:0005488;small molecule binding#GO:0036094 nitrogen compound transport#GO:0071705;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;vitamin transport#GO:0051180 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008349.1|UniProtKB=W5MP28 W5MP28 PTHR46678:SF1 LECITHIN RETINOL ACYLTRANSFERASE LECITHIN RETINOL ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 small molecule metabolic process#GO:0044281;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;cellular process#GO:0009987;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000010224.1|UniProtKB=W5MVX2 W5MVX2 PTHR46318:SF5 UPSTREAM BINDING TRANSCRIPTION FACTOR NUCLEOLAR TRANSCRIPTION FACTOR 1 ISOFORM X1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase I#GO:0006356;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;transcription by RNA polymerase I#GO:0006360;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase I#GO:0045943;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007477.1|UniProtKB=W5ML15 W5ML15 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012614.1|UniProtKB=W5N4H2 W5N4H2 PTHR44200:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005930.1|UniProtKB=W5MFJ8 W5MFJ8 PTHR21258:SF44 DOCKING PROTEIN RELATED DOCKING PROTEIN 4 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002802.1|UniProtKB=W5M4J1 W5M4J1 PTHR13943:SF31 HRAS-LIKE SUPPRESSOR - RELATED RETINOIC ACID RECEPTOR RESPONDER 3-RELATED glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;transferase activity#GO:0016740;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;A2-type glycerophospholipase activity#GO:0004623;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000942.1|UniProtKB=W5LY42 W5LY42 PTHR14453:SF107 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE glycosyltransferase activity#GO:0016757;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;transcription regulator activity#GO:0140110 negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biological process#GO:0048519;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of gene expression#GO:0010629;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000013225.1|UniProtKB=W5N6N2 W5N6N2 PTHR46096:SF12 PERFORIN-1 PERFORIN 1.1-RELATED wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 T cell mediated immunity#GO:0002456;cell recognition#GO:0008037;cell activation#GO:0001775;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;response to virus#GO:0009615;defense response to virus#GO:0051607;leukocyte activation#GO:0045321;leukocyte mediated cytotoxicity#GO:0001909;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;immune effector process#GO:0002252;cell killing#GO:0001906;response to external stimulus#GO:0009605;defense response#GO:0006952;cell-cell recognition#GO:0009988;immune response#GO:0006955;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;adaptive immune response#GO:0002250;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009909.1|UniProtKB=W5MUQ0 W5MUQ0 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011222.1|UniProtKB=W5MZI1 W5MZI1 PTHR24343:SF306 SERINE/THREONINE KINASE 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;negative regulation of signal transduction#GO:0009968;negative regulation of TORC1 signaling#GO:1904262;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;localization#GO:0051179;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;response to nutrient levels#GO:0031667;cellular response to glucose starvation#GO:0042149;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;intracellular protein localization#GO:0008104;regulation of TORC1 signaling#GO:1903432 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 LEPOC|Ensembl=ENSLOCG00000006345.1|UniProtKB=W5MH04 W5MH04 PTHR10165:SF25 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;cell communication#GO:0007154;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;signal transduction#GO:0007165;lipid modification#GO:0030258;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000990.1|UniProtKB=W5LYA8 W5LYA8 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000005580.1|UniProtKB=W5MEC5 W5MEC5 PTHR20863:SF80 ACYL CARRIER PROTEIN ACYL CARRIER PROTEIN, MITOCHONDRIAL molecular carrier activity#GO:0140104;binding#GO:0005488;small molecule binding#GO:0036094 transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000017121.1|UniProtKB=W5NKJ9 W5NKJ9 PTHR30612:SF11 SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM PROTEIN TRANSLOCASE SUBUNIT SECA-LIKE ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016089.1|UniProtKB=W5NGR2 W5NGR2 PTHR21206:SF0 SLD5 PROTEIN DNA REPLICATION COMPLEX GINS PROTEIN SLD5 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;DNA replication preinitiation complex#GO:0031261;chromosome#GO:0005694;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000006967.1|UniProtKB=W5MJ69 W5MJ69 PTHR23277:SF106 NECTIN-RELATED NECTIN 1A-LIKE ISOFORM X1-RELATED binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011513.1|UniProtKB=W5N0J1 W5N0J1 PTHR11377:SF7 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;localization within membrane#GO:0051668;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000003199.1|UniProtKB=W5M5X3 W5M5X3 PTHR46789:SF2 FORKHEAD BOX PROTEIN R1 FORKHEAD BOX PROTEIN R2 nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000007888.1|UniProtKB=W5MMH5 W5MMH5 PTHR11818:SF54 BETA/GAMMA CRYSTALLIN BETAA1C-CRYSTALLIN-RELATED structural molecule activity#GO:0005198 developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000017676.1|UniProtKB=W5NMC2 W5NMC2 PTHR23267:SF486 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14_DELTA VARIABLE 4 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014331.1|UniProtKB=W5NAI8 W5NAI8 PTHR15012:SF35 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM4 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cortical cytoskeleton#GO:0030863;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;apical junction complex#GO:0043296;apical part of cell#GO:0045177;membraneless organelle#GO:0043228;cell junction#GO:0030054;adherens junction#GO:0005912;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000005524.1|UniProtKB=W5ME69 W5ME69 PTHR45734:SF1 TENSIN TENSIN-2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000007938.1|UniProtKB=W5MMM8 W5MMM8 PTHR45981:SF1 LD02310P E3 UBIQUITIN-PROTEIN LIGASE MARCHF1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;MHC protein binding#GO:0042287;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response#GO:0006955;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;response to stimulus#GO:0050896;protein modification by small protein conjugation or removal#GO:0070647;immune system process#GO:0002376;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;antigen processing and presentation#GO:0019882 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;early endosome membrane#GO:0031901;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vacuole#GO:0005773;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000000861.1|UniProtKB=W5LXV1 W5LXV1 PTHR23266:SF322 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-2 antigen binding#GO:0003823;binding#GO:0005488 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004251.1|UniProtKB=W5M9M1 W5M9M1 PTHR12326:SF10 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 3 LEPOC|Ensembl=ENSLOCG00000013705.1|UniProtKB=W5N8D7 W5N8D7 PTHR24247:SF32 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2C transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414 LEPOC|Ensembl=ENSLOCG00000009790.1|UniProtKB=W5MUA7 W5MUA7 PTHR14196:SF4 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED-RELATED 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;renal system development#GO:0072001;negative regulation of macromolecule biosynthetic process#GO:0010558;kidney development#GO:0001822;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010680.1|UniProtKB=W5MXH3 W5MXH3 PTHR12446:SF34 TESMIN/TSO1-RELATED PROTEIN LIN-54 HOMOLOG-RELATED regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000004186.1|UniProtKB=W5M9D9 W5M9D9 NAAA PTHR28583:SF4 ACID AMIDASE N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000017331.1|UniProtKB=W5NLC7 W5NLC7 PTHR22791:SF39 RING-TYPE DOMAIN-CONTAINING PROTEIN RING FINGER PROTEIN 183 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008038.1|UniProtKB=W5MN03 W5MN03 PTHR24355:SF12 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RHODOPSIN KINASE GRK7 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 LEPOC|Ensembl=ENSLOCG00000003287.1|UniProtKB=W5M685 W5M685 PTHR14418:SF5 CONDENSIN COMPLEX SUBUNIT 3-RELATED CONDENSIN COMPLEX SUBUNIT 3 nuclear division#GO:0000280;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070 condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;condensin complex#GO:0000796;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000009886.1|UniProtKB=W5MUM2 W5MUM2 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;aminoglycan biosynthetic process#GO:0006023;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000001345.1|UniProtKB=W5LZH1 W5LZH1 PTHR12684:SF2 PUTATIVE PHOSPHOTRANSFERASE TRNA 2'-PHOSPHOTRANSFERASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA splicing#GO:0008380;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011768.1|UniProtKB=W5N1G5 W5N1G5 PTHR10870:SF0 CELL CYCLE CHECKPOINT PROTEIN RAD1 CELL CYCLE CHECKPOINT PROTEIN RAD1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;DNA integrity checkpoint signaling#GO:0031570;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;cellular response to stress#GO:0033554;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of cell cycle#GO:0045786;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075 condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 LEPOC|Ensembl=ENSLOCG00000003451.1|UniProtKB=W5M6U5 W5M6U5 PTHR11596:SF90 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 tissue development#GO:0009888;ossification#GO:0001503;multicellular organismal process#GO:0032501;developmental process#GO:0032502;biomineral tissue development#GO:0031214;bone mineralization#GO:0030282;animal gross anatomical part developmental process#GO:0160108;animal organ development#GO:0048513;anatomical structure development#GO:0048856 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000006023.1|UniProtKB=W5MFZ2 W5MFZ2 PTHR13992:SF21 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR NUCLEAR RECEPTOR COREPRESSOR 2 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 Notch signaling pathway#P00045>CoR#P01112;Huntington disease#P00029>N-CoR#P00770 LEPOC|Ensembl=ENSLOCG00000007512.1|UniProtKB=W5ML54 W5ML54 PTHR22923:SF5 CEREBELLIN-RELATED CEREBELLIN-1 cell junction#GO:0030054;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016980.1|UniProtKB=W5NK32 W5NK32 PTHR15576:SF1 RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1 RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1 UDP-glycosyltransferase activity#GO:0008194;xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015679.1|UniProtKB=W5NF93 W5NF93 PTHR12805:SF0 KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG DNA_RNA-BINDING PROTEIN KIN17 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676 response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007710.1|UniProtKB=W5MLV1 W5MLV1 PTHR47958:SF30 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX59-RELATED catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000013124.1|UniProtKB=W5N6B2 W5N6B2 PTHR10822:SF24 GLYPICAN GLYPICAN-2 cell communication#GO:0007154;regulation of protein localization#GO:0032880;smoothened signaling pathway#GO:0007224;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;regulation of localization#GO:0032879;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of protein localization to membrane#GO:1905475;cell migration#GO:0016477;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;cell surface#GO:0009986;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009383.1|UniProtKB=W5MST9 W5MST9 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000002254.1|UniProtKB=W5M2L9 W5M2L9 PTHR10699:SF28 NEUROMODULIN NEUROGRANIN (PROTEIN KINASE C SUBSTRATE, RC3) B ISOFORM X1 calmodulin binding#GO:0005516;binding#GO:0005488;protein binding#GO:0005515 LEPOC|Ensembl=ENSLOCG00000018209.1|UniProtKB=W5NNV1 W5NNV1 PTHR26451:SF866 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002855.1|UniProtKB=W5M4P6 W5M4P6 PTHR23507:SF3 ZGC:174356 SOLUTE CARRIER FAMILY 46 MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014847.1|UniProtKB=W5NCD2 W5NCD2 PTHR13900:SF0 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1 transcription factor binding#GO:0008134;binding#GO:0005488;protein binding#GO:0005515 protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000013988.1|UniProtKB=W5N9D7 W5N9D7 PTHR13021:SF8 PRE-MRNA-SPLICING FACTOR ISY1 PRE-MRNA-SPLICING FACTOR ISY1 HOMOLOG mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000005740.1|UniProtKB=W5MEX4 W5MEX4 PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054 regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of biosynthetic process#GO:0009889;chromosome organization#GO:0051276;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003934.1|UniProtKB=W5M8J2 W5M8J2 PTHR34072:SF66 ENZYMATIC POLYPROTEIN-RELATED REVERSE TRANSCRIPTASE LEPOC|Ensembl=ENSLOCG00000012002.1|UniProtKB=W5N299 W5N299 PTHR10671:SF85 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 1 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000004806.1|UniProtKB=W5MBL4 W5MBL4 PTHR13467:SF3 CUE DOMAIN CONTAINING PROTEIN 1 CUE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006790.1|UniProtKB=W5MIJ9 W5MIJ9 PTHR18945:SF751 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-7 molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215 transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;trans-synaptic signaling#GO:0099537;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;metal ion transport#GO:0030001 axon#GO:0030424;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495;cell body#GO:0044297;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;neuron projection#GO:0043005;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000003388.1|UniProtKB=W5M6K0 W5M6K0 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000016872.1|UniProtKB=W5NJP7 W5NJP7 PTHR24340:SF24 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000017541.1|UniProtKB=W5NLY7 W5NLY7 PTHR24225:SF77 CHEMOTACTIC RECEPTOR C3A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004146.1|UniProtKB=W5M9A8 W5M9A8 PTHR24006:SF647 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000004424.1|UniProtKB=W5MA76 W5MA76 PTHR19282:SF471 TETRASPANIN CD63 ANTIGEN regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017254.1|UniProtKB=W5NL33 W5NL33 PTHR11984:SF105 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell communication#GO:0007154;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;cell junction#GO:0030054 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000017910.1|UniProtKB=W5NN04 W5NN04 PTHR11537:SF250 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 5 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;potassium ion transport#GO:0006813;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 anchoring junction#GO:0070161;intercalated disc#GO:0014704;transmembrane transporter complex#GO:1902495;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell-cell contact zone#GO:0044291;transporter complex#GO:1990351;cell junction#GO:0030054;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000007133.1|UniProtKB=W5MJS3 W5MJS3 PTHR46092:SF2 HOMEOBOX PROTEIN HOX-A11-RELATED HOMEOBOX PROTEIN HOX-D11 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;skeletal system development#GO:0001501 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000017392.1|UniProtKB=W5NLI8 W5NLI8 PTHR24232:SF51 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015151.1|UniProtKB=W5NDE5 W5NDE5 PTHR24355:SF26 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005903.1|UniProtKB=W5MFH9 W5MFH9 PTHR15463:SF2 AP1 GAMMA SUBUNIT BINDING PROTEIN 1 SYNERGIN GAMMA cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular organelle#GO:0043229;coated membrane#GO:0048475;coated vesicle#GO:0030135;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network transport vesicle#GO:0030140;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 LEPOC|Ensembl=ENSLOCG00000014427.1|UniProtKB=W5NAV2 W5NAV2 PTHR45796:SF2 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P3 ISOFORM X1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000010794.1|UniProtKB=W5MXW9 W5MXW9 PTHR12170:SF5 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE RMND5A acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000009090.1|UniProtKB=W5MRS3 W5MRS3 PTHR31914:SF2 PROTEIN FAM163A PROTEIN FAM163A LEPOC|Ensembl=ENSLOCG00000005855.1|UniProtKB=W5MFA9 W5MFA9 PTHR12782:SF5 MICROSOMAL PROSTAGLANDIN E SYNTHASE-2 PROSTAGLANDIN E SYNTHASE 2 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006886.1|UniProtKB=W5MIW6 W5MIW6 PTHR12050:SF3 LEPTIN RECEPTOR-RELATED LEPTIN RECEPTOR GENE-RELATED PROTEIN endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147 vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005725.1|UniProtKB=W5MEV6 W5MEV6 PTHR12706:SF8 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH HOMOLOG 1 protein binding#GO:0005515;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;histone binding#GO:0042393;chromatin binding#GO:0003682 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000011621.1|UniProtKB=W5N0X1 W5N0X1 PTHR12709:SF1 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014583.1|UniProtKB=W5NBD7 W5NBD7 PTHR10231:SF106 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-GALACTOSE TRANSLOCATOR carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;UDP-galactose transmembrane transporter activity#GO:0005459;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;nucleotide-sugar transmembrane transport#GO:0015780;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012964.1|UniProtKB=W5N5S1 W5N5S1 PTHR24033:SF229 EGF-LIKE DOMAIN-CONTAINING PROTEIN ATTRACTIN-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017073.1|UniProtKB=W5NKE1 W5NKE1 PTHR22951:SF4 CLATHRIN ASSEMBLY PROTEIN CLATHRIN COAT ASSEMBLY PROTEIN AP180 small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;phospholipid binding#GO:0005543;clathrin binding#GO:0030276;SNARE binding#GO:0000149;phosphatidylinositol phosphate binding#GO:1901981 transport#GO:0006810;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;membrane organization#GO:0061024;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane#GO:0005886;clathrin-coated vesicle#GO:0030136;synaptic membrane#GO:0097060;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000011457.1|UniProtKB=W5N0B7 W5N0B7 PTHR24403:SF102 ZINC FINGER PROTEIN RE1-SILENCING TRANSCRIPTION FACTOR double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of developmental process#GO:0050793;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cell differentiation#GO:0045595;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of neuron differentiation#GO:0045664;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000005192.1|UniProtKB=W5MCZ1 W5MCZ1 PTHR45689:SF11 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 2 voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 transmembrane transporter complex#GO:1902495;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;transporter complex#GO:1990351;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000010127.1|UniProtKB=W5MVJ4 W5MVJ4 PTHR14131:SF6 ANOSMIN ANOSMIN-1 ISOFORM X1-RELATED generation of neurons#GO:0048699;neuron differentiation#GO:0030182;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;cellular process#GO:0009987;nervous system development#GO:0007399;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000017166.1|UniProtKB=W5NKQ9 W5NKQ9 PTHR14965:SF2 SI:CH73-248E21.1 BCL-2-LIKE PROTEIN 12 regulation of cellular response to stress#GO:0080135;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of intrinsic apoptotic signaling pathway#GO:2001242;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of apoptotic process#GO:0042981;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of programmed cell death#GO:0043069 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017258.1|UniProtKB=W5NL37 W5NL37 PTHR10340:SF24 SPHINGOMYELIN PHOSPHODIESTERASE CYCLIC GMP-AMP PHOSPHODIESTERASE SMPDL3A phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000008115.1|UniProtKB=W5MN96 W5MN96 PTHR24161:SF109 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN CONTAINING 4B protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010749.1|UniProtKB=W5MXR7 W5MXR7 PTHR24034:SF49 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 2 binding#GO:0005488;extracellular matrix binding#GO:0050840 supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000001492.1|UniProtKB=W5LZZ6 W5LZZ6 PTHR46615:SF1 ARYLSULFATASE K ARYLSULFATASE K catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 LEPOC|Ensembl=ENSLOCG00000015861.1|UniProtKB=W5NFW9 W5NFW9 PTHR11769:SF9 HYALURONIDASE HYALURONIDASE macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;glycosaminoglycan catabolic process#GO:0006027;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000016242.1|UniProtKB=W5NHB7 W5NHB7 PTHR16650:SF10 C21ORF13-RELATED LEBERCILIN intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073 axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000010315.1|UniProtKB=W5MW77 W5MW77 PTHR18863:SF5 TSEC-2-RELATED TESTIS EXPRESSED GENE 21 LEPOC|Ensembl=ENSLOCG00000006598.1|UniProtKB=W5MHX2 W5MHX2 PTHR43206:SF1 AMINOTRANSFERASE 4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216 Pyrimidine Metabolism#P02771>Aminotransferase#P03129;Aminobutyrate degradation#P02726>4-aminobutyrate aminotransferase#P02825;Gamma-aminobutyric acid synthesis#P04384>GABA aminotransferase#P04480 LEPOC|Ensembl=ENSLOCG00000004389.1|UniProtKB=W5MAF0 W5MAF0 PTHR10663:SF137 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 1 cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Golgi organization#GO:0007030 Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000010442.1|UniProtKB=W5MWP8 W5MWP8 PTHR45794:SF1 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011771.1|UniProtKB=W5N1G8 W5N1G8 PTHR46513:SF5 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED PRO-EPIDERMAL GROWTH FACTOR receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signaling#GO:0023056;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of cell population proliferation#GO:0008284 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGF#P00549;Gonadotropin-releasing hormone receptor pathway#P06664>EGF#P06745 LEPOC|Ensembl=ENSLOCG00000001608.1|UniProtKB=W5M0F5 W5M0F5 PTHR16266:SF26 WD REPEAT DOMAIN 9 BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000004006.1|UniProtKB=W5M8U1 W5M8U1 PTHR21694:SF35 COILED-COIL DOMAIN-CONTAINING PROTEIN 63 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 1 cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium movement#GO:0003341;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031 organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013498.1|UniProtKB=W5N7M9 W5N7M9 PTHR43899:SF10 RH59310P 20BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006481.1|UniProtKB=W5MHH8 W5MHH8 PTHR31139:SF4 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG ECTOPIC P GRANULES PROTEIN 5 HOMOLOG lysosome#GO:0005764;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 LEPOC|Ensembl=ENSLOCG00000010832.1|UniProtKB=W5MY18 W5MY18 PTHR23189:SF14 RNA RECOGNITION MOTIF-CONTAINING PARASPECKLE COMPONENT 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011203.1|UniProtKB=W5MZF7 W5MZF7 PTHR14096:SF57 APOLIPOPROTEIN L APOLIPOPROTEIN L4 lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical structure#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014237.1|UniProtKB=W5NA72 W5NA72 PTHR13244:SF7 ZINC FINGER MYND DOMAIN CONTAINING PROTEIN 10 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 10 protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;plasma membrane bounded cell projection assembly#GO:0120031;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;inner dynein arm assembly#GO:0036159;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;organelle assembly#GO:0070925;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;centriolar satellite#GO:0034451;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000004498.1|UniProtKB=W5MAH6 W5MAH6 PTHR22455:SF10 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 LEPOC|Ensembl=ENSLOCG00000006253.1|UniProtKB=W5MGQ0 W5MGQ0 PTHR14038:SF4 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2B RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002083.1|UniProtKB=W5M208 W5M208 PTHR21041:SF3 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN OSTEOCLAST STIMULATORY TRANSMEMBRANE PROTEIN cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;osteoclast differentiation#GO:0030316;sexual reproduction#GO:0019953;developmental process#GO:0032502;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;hemopoiesis#GO:0030097;fertilization#GO:0009566;cell development#GO:0048468;reproductive process#GO:0022414;single fertilization#GO:0007338;leukocyte differentiation#GO:0002521;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000015063.1|UniProtKB=W5ND28 W5ND28 PTHR17490:SF14 SUA5 THREONYLCARBAMOYL-AMP SYNTHASE RNA binding#GO:0003723;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000014777.1|UniProtKB=W5NC36 W5NC36 PTHR22765:SF468 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF128A PRECURSOR ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016228.1|UniProtKB=W5NHA1 W5NHA1 PTHR48023:SF2 D-XYLOSE-PROTON SYMPORTER-LIKE 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 12 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 circulatory system development#GO:0072359;carbohydrate transmembrane transport#GO:0034219;multicellular organismal process#GO:0032501;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;multicellular organism development#GO:0007275;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;carbohydrate transport#GO:0008643;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000018145.1|UniProtKB=W5NNN7 W5NNN7 PTHR10666:SF173 UBIQUITIN UBIQUITIN-LIKE PROTEIN NEDD8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 regulation of proteolysis#GO:0030162;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000005995.1|UniProtKB=W5MFT6 W5MFT6 PTHR31840:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 LEPOC|Ensembl=ENSLOCG00000009238.1|UniProtKB=W5MSB0 W5MSB0 PTHR45629:SF14 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 2 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000003802.1|UniProtKB=W5M828 W5M828 PTHR21538:SF26 ANILLIN/RHOTEKIN RTKN ANILLIN, ACTIN BINDING PROTEIN 2 ISOFORM X1 cellular component organization#GO:0016043;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;mitotic cell cycle#GO:0000278;actomyosin structure organization#GO:0031032;cytokinesis#GO:0000910;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cytokinetic process#GO:0032506;cortical actin cytoskeleton organization#GO:0030866;septin ring organization#GO:0031106;cytoskeleton-dependent cytokinesis#GO:0061640;actomyosin contractile ring assembly#GO:0000915;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;septin cytoskeleton organization#GO:0032185;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;membraneless organelle#GO:0043228;actomyosin contractile ring#GO:0005826;contractile ring#GO:0070938;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000013176.1|UniProtKB=W5N6H0 W5N6H0 PTHR10678:SF3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 COP9 SIGNALOSOME COMPLEX SUBUNIT 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687 intracellular organelle#GO:0043229;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000003687.1|UniProtKB=W5M7L9 W5M7L9 PTHR24248:SF140 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR HISTAMINE H3 RECEPTOR transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005184.1|UniProtKB=W5MCY6 W5MCY6 PTHR23007:SF3 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL-B catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;protein kinase binding#GO:0019901 negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane raft#GO:0045121;membrane microdomain#GO:0098857;cell periphery#GO:0071944 ligase#PC00142 EGF receptor signaling pathway#P00018>c-Cbl#P00544 LEPOC|Ensembl=ENSLOCG00000002888.1|UniProtKB=W5M4T8 W5M4T8 PTHR31526:SF2 SOSS COMPLEX SUBUNIT C SOSS COMPLEX SUBUNIT C nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000007297.1|UniProtKB=W5MKC7 W5MKC7 PTHR15192:SF15 PROTEIN CBG05349 OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 1 signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 negative regulation of cellular process#GO:0048523;negative regulation of cell growth#GO:0030308;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cell growth#GO:0001558;regulation of biological process#GO:0050789;regulation of growth#GO:0040008;negative regulation of biological process#GO:0048519 LEPOC|Ensembl=ENSLOCG00000007236.1|UniProtKB=W5MK49 W5MK49 PTHR12439:SF40 PLACENTAL PROTEIN 11-RELATED URIDYLATE-SPECIFIC ENDORIBONUCLEASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional gene silencing#GO:0016441 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016923.1|UniProtKB=W5NJW0 W5NJW0 PTHR14274:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 8 SMALL INTEGRAL MEMBRANE PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000009031.1|UniProtKB=W5MRJ5 W5MRJ5 PTHR24340:SF121 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-3.2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000017834.1|UniProtKB=W5NMS8 W5NMS8 PTHR36471:SF1 SMALL MEMBRANE A-KINASE ANCHOR PROTEIN A-KINASE ANCHORING PROTEIN 19 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014802.1|UniProtKB=W5NC66 W5NC66 PTHR23327:SF41 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006586.1|UniProtKB=W5MHU4 W5MHU4 PTHR38653:SF1 GENE 572-RELATED CILIATED LEFT-RIGHT ORGANIZER ZP-N DOMAINS-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010249.1|UniProtKB=W5MVY4 W5MVY4 PTHR45837:SF3 VESICLE-TRAFFICKING PROTEIN SEC22B VESICLE-TRAFFICKING PROTEIN SEC22B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;membrane fusion#GO:0061025;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;Golgi organization#GO:0007030 coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;SNARE complex#GO:0031201;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;ER to Golgi transport vesicle membrane#GO:0012507;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506 LEPOC|Ensembl=ENSLOCG00000009241.1|UniProtKB=W5MSC2 W5MSC2 PTHR23316:SF6 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-4 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012113.1|UniProtKB=W5N2P0 W5N2P0 PTHR34262:SF1 TRANSMEMBRANE PROTEIN 220 TRANSMEMBRANE PROTEIN 220 LEPOC|Ensembl=ENSLOCG00000013269.1|UniProtKB=W5N6U6 W5N6U6 PTHR10574:SF378 NETRIN/LAMININ-RELATED NETRIN-1 multicellular organismal process#GO:0032501;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;anatomical structure development#GO:0048856;system development#GO:0048731;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;dendrite development#GO:0016358;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 LEPOC|Ensembl=ENSLOCG00000011599.1|UniProtKB=W5N0V6 W5N0V6 PTHR10288:SF158 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 3 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;system development#GO:0048731;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012963.1|UniProtKB=W5N5Q7 W5N5Q7 PTHR21580:SF64 SHIPPO-1-RELATED SPERM-TAIL PG-RICH REPEAT-CONTAINING PROTEIN 2 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005157.1|UniProtKB=W5MCU9 W5MCU9 PTHR11232:SF79 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PID DOMAIN-CONTAINING PROTEIN signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 membrane invagination#GO:0010324;transport#GO:0006810;phagocytosis#GO:0006909;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;cellular component organization#GO:0016043;membrane organization#GO:0061024;endocytosis#GO:0006897 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012775.1|UniProtKB=W5N530 W5N530 PTHR24223:SF176 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 2 transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;xenobiotic transmembrane transporter activity#GO:0042910;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000015893.1|UniProtKB=W5NG14 W5NG14 PTHR19134:SF461 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;central nervous system development#GO:0007417;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;neuron differentiation#GO:0030182;gliogenesis#GO:0042063;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;glial cell differentiation#GO:0010001;oligodendrocyte differentiation#GO:0048709;multicellular organismal process#GO:0032501 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001986.1|UniProtKB=W5M1W3 W5M1W3 PTHR14226:SF23 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 7 catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 hydrolase#PC00121;esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000004404.1|UniProtKB=W5MA52 W5MA52 MED8 PTHR13074:SF9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000014091.1|UniProtKB=W5N9Q8 W5N9Q8 PTHR42884:SF8 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 6 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;proteolysis#GO:0006508;biological regulation#GO:0065007;biosynthetic process#GO:0009058;hormone metabolic process#GO:0042445;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;peptide hormone processing#GO:0016486;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cell surface#GO:0009986;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;extracellular matrix#GO:0031012;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;external encapsulating structure#GO:0030312;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 LEPOC|Ensembl=ENSLOCG00000004927.1|UniProtKB=W5MC15 W5MC15 PTHR31334:SF1 SMITH-MAGENIS SYNDROME REGION GENE 8 PROTEIN GUANINE NUCLEOTIDE EXCHANGE PROTEIN SMCR8 intracellular protein-containing complex#GO:0140535;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000001985.1|UniProtKB=W5M1N8 W5M1N8 PTHR14186:SF23 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED KAZAL-TYPE SERINE PEPTIDASE INHIBITOR DOMAIN 2 PRECURSOR signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000000016.1|UniProtKB=W5LV59 W5LV59 PTHR11266:SF28 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN negative regulation of signaling#GO:0023057;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of programmed cell death#GO:0043069;negative regulation of response to stimulus#GO:0048585;regulation of membrane permeability#GO:0090559;negative regulation of apoptotic process#GO:0043066;negative regulation of signal transduction#GO:0009968;regulation of mitochondrial membrane permeability#GO:0046902;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013870.1|UniProtKB=W5N904 W5N904 PTHR43520:SF29 ATP7, ISOFORM B COPPER-TRANSPORTING ATPASE 1 transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;cation binding#GO:0043169;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;transition metal ion transmembrane transporter activity#GO:0046915;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion binding#GO:0046872;transporter activity#GO:0005215;copper ion binding#GO:0005507;metal ion transmembrane transporter activity#GO:0046873;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075 intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;copper ion transmembrane transport#GO:0035434 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000004053.1|UniProtKB=W5M8Y4 W5M8Y4 PTHR45905:SF6 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN GOLGI ASSOCIATED, GAMMA ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN 2 protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme binding#GO:0019899;binding#GO:0005488 macromolecule localization#GO:0033036;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization within membrane#GO:0051668;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000003425.1|UniProtKB=W5M6P4 W5M6P4 PTHR24243:SF205 G-PROTEIN COUPLED RECEPTOR NEUROMEDIN-U RECEPTOR 2 signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007038.1|UniProtKB=W5MJG2 W5MJG2 PTHR10865:SF24 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 1 binding#GO:0005488;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;histone deacetylase binding#GO:0042826;protein binding#GO:0005515 regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009021.1|UniProtKB=W5MRJ4 W5MRJ4 PTHR10082:SF15 INTEGRIN BETA SUBUNIT INTEGRIN BETA-2 cell adhesion molecule binding#GO:0050839;integrin binding#GO:0005178;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;enzyme binding#GO:0019899;peptide binding#GO:0042277;protein kinase binding#GO:0019901;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cell surface receptor signaling pathway#GO:0007166;neutrophil chemotaxis#GO:0030593;neutrophil migration#GO:1990266;response to chemical#GO:0042221;taxis#GO:0042330;granulocyte migration#GO:0097530;leukocyte cell-cell adhesion#GO:0007159;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte chemotaxis#GO:0030595;cell adhesion mediated by integrin#GO:0033627;leukocyte migration#GO:0050900;biological regulation#GO:0065007;cell migration#GO:0016477;cell chemotaxis#GO:0060326;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;chemotaxis#GO:0006935;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;signaling receptor complex#GO:0043235;anchoring junction#GO:0070161;integrin complex#GO:0008305;cell junction#GO:0030054 integrin#PC00126 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin beta#P00931 LEPOC|Ensembl=ENSLOCG00000016007.1|UniProtKB=W5NGG2 W5NGG2 PHTF2 PTHR12680:SF2 PUTATIVE HOMEODOMAIN TRANSCRIPTION FACTOR PHTF PROTEIN PHTF2 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002309.1|UniProtKB=W5M2U8 W5M2U8 PTHR24418:SF53 TYROSINE-PROTEIN KINASE PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102 ERBB signaling pathway#GO:0038127;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;epidermal growth factor receptor signaling pathway#GO:0007173;negative regulation of response to stimulus#GO:0048585;nuclear receptor-mediated signaling pathway#GO:0141193;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;regulation of intrinsic apoptotic signaling pathway#GO:2001242;steroid hormone receptor signaling pathway#GO:0043401;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;intracellular receptor signaling pathway#GO:0030522;response to steroid hormone#GO:0048545;regulation of apoptotic signaling pathway#GO:2001233;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;negative regulation of apoptotic signaling pathway#GO:2001234;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;cell surface receptor signaling pathway#GO:0007166;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of apoptotic process#GO:0042981;cellular response to steroid hormone stimulus#GO:0071383;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;negative regulation of intracellular signal transduction#GO:1902532;hormone-mediated signaling pathway#GO:0009755;negative regulation of cell communication#GO:0010648 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Cadherin signaling pathway#P00012>Src#P00468;CCKR signaling map#P06959>p62 SRC#P07047;Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940;Angiogenesis#P00005>Src#P00184;CCKR signaling map#P06959>p54 SRC#P07109;CCKR signaling map#P06959>SRC#P07202;CCKR signaling map#P06959>SRC @Galphaq#P07163;Gonadotropin-releasing hormone receptor pathway#P06664>SRC#P06844;CCKR signaling map#P06959>p60 SRC#P07207 LEPOC|Ensembl=ENSLOCG00000014597.1|UniProtKB=W5NBF2 W5NBF2 PTHR12547:SF157 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;mRNA binding#GO:0003729;translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730;molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517 negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010799.1|UniProtKB=W5MXY2 W5MXY2 PTHR13055:SF11 TUMOR ENDOTHELIAL MARKER 7 RELATED PLEXIN DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000007547.1|UniProtKB=W5MLA0 W5MLA0 PTHR43829:SF13 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-10 water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;carbohydrate transmembrane transporter activity#GO:0015144 fluid transport#GO:0042044;organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;water transport#GO:0006833;transport#GO:0006810;carbohydrate transport#GO:0008643;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014933.1|UniProtKB=W5NCM5 W5NCM5 PTHR13058:SF22 THREE PRIME REPAIR EXONUCLEASE 1, 2 EXODEOXYRIBONUCLEASE III 3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000014926.1|UniProtKB=W5NCM3 W5NCM3 PTHR13136:SF16 TESTIS DEVELOPMENT PROTEIN PRTD KAT8 REGULATORY NSL COMPLEX SUBUNIT 3 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000016615.1|UniProtKB=W5NIR6 W5NIR6 PTHR23069:SF5 AAA DOMAIN-CONTAINING ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2B hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;histone binding#GO:0042393 positive regulation of biosynthetic process#GO:0009891;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;protein-containing complex disassembly#GO:0032984;transcription by RNA polymerase II#GO:0006366;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleosome organization#GO:0034728;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;nucleic acid biosynthetic process#GO:0141187;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;DNA-templated transcription initiation#GO:0006352;chromatin remodeling#GO:0006338;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;transcription initiation-coupled chromatin remodeling#GO:0045815;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010707.1|UniProtKB=W5MXK8 W5MXK8 PTHR11890:SF48 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR-LIKE 1 ISOFORM X1 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005913.1|UniProtKB=W5MFI4 W5MFI4 PTHR11579:SF4 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000006534.1|UniProtKB=W5MHN7 W5MHN7 PTHR47958:SF10 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX39A catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolic process#GO:0016070;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nucleic acid transport#GO:0050657;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA splicing, via transesterification reactions#GO:0000375;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;RNA biosynthetic process#GO:0032774;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000010953.1|UniProtKB=W5MYI0 W5MYI0 PTHR12375:SF47 RNA-BINDING PROTEIN LUC7-RELATED LUC7-LIKE PROTEIN 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site recognition#GO:0006376;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245 U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003175.1|UniProtKB=W5M5U2 W5M5U2 PTHR34754:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 60 COILED-COIL DOMAIN-CONTAINING PROTEIN 60 LEPOC|Ensembl=ENSLOCG00000016459.1|UniProtKB=W5NI72 W5NI72 PTHR46048:SF10 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018154.1|UniProtKB=W5NNP6 W5NNP6 PTHR13952:SF31 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 35 KDA PROTEIN mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000014000.1|UniProtKB=W5N9E5 W5N9E5 PTHR24340:SF33 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016335.1|UniProtKB=W5NHQ6 W5NHQ6 PTHR24072:SF13 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOQ small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;signaling#GO:0023052;response to stimulus#GO:0050896;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;localization#GO:0051179;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Huntington disease#P00029>Rac#P00775;EGF receptor signaling pathway#P00018>Rac#P00564 LEPOC|Ensembl=ENSLOCG00000013318.1|UniProtKB=W5N705 W5N705 PTHR22780:SF13 ADAPTIN, ALPHA/GAMMA/EPSILON AP-4 COMPLEX SUBUNIT EPSILON-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006720.1|UniProtKB=W5MIA8 W5MIA8 PTHR14309:SF8 EXPRESSED PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY B MEMBER 2 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000007907.1|UniProtKB=W5MMJ4 W5MMJ4 PTHR11575:SF48 5'-NUCLEOTIDASE-RELATED ECTO-5'-NUCLEOTIDASE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000157.1|UniProtKB=W5LVL5 W5LVL5 PTHR10492:SF109 FAMILY NOT NAMED ATP-DEPENDENT DNA HELICASE LEPOC|Ensembl=ENSLOCG00000016717.1|UniProtKB=W5NJ46 W5NJ46 PTHR23240:SF37 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED PROTEIN ARTEMIS catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;damaged DNA binding#GO:0003684;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;DNA binding#GO:0003677;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;telomere organization#GO:0032200;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nonhomologous end joining complex#GO:0070419;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;DNA repair complex#GO:1990391;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010420.1|UniProtKB=W5MWL8 W5MWL8 PTHR11636:SF43 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006867.1|UniProtKB=W5MIU4 W5MIU4 PTHR21329:SF3 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q-RELATED PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000015527.1|UniProtKB=W5NEQ2 W5NEQ2 PTHR10751:SF100 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 1 ISOFORM X1-RELATED hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000018236.1|UniProtKB=W5NNX8 W5NNX8 PTHR10605:SF18 HEPARAN SULFATE SULFOTRANSFERASE SULFOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000013465.1|UniProtKB=W5N7J8 W5N7J8 PTHR28638:SF2 CELL CYCLE PROGRESSION PROTEIN 1 CELL CYCLE PROGRESSION PROTEIN 1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000003776.1|UniProtKB=W5M7Z3 W5M7Z3 PTHR12686:SF8 3'-5' EXORIBONUCLEASE CSL4-RELATED EXOSOME COMPLEX COMPONENT CSL4 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;ribosome biogenesis#GO:0042254;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 exoribonuclease#PC00099;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002246.1|UniProtKB=W5M2K9 W5M2K9 PTHR24388:SF48 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR SCRATCH 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000014865.1|UniProtKB=W5NCF1 W5NCF1 PTHR24213:SF17 ACTIN-BINDING LIM PROTEIN DEMATIN binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;lamellipodium assembly#GO:0030032;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000008446.1|UniProtKB=W5MPH9 W5MPH9 PTHR13407:SF2 RNF121 PROTEIN RING FINGER PROTEIN 175 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012770.1|UniProtKB=W5N503 W5N503 ZFAND6 PTHR10634:SF25 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 6 binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;protein binding#GO:0005515 establishment of localization#GO:0051234;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of protein localization#GO:0045184 LEPOC|Ensembl=ENSLOCG00000011088.1|UniProtKB=W5MZ11 W5MZ11 PTHR21077:SF7 EME1 PROTEIN STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT EME1 DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;DNA integrity checkpoint signaling#GO:0031570;resolution of meiotic recombination intermediates#GO:0000712;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;mitotic cell cycle process#GO:1903047;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;homologous recombination#GO:0035825;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;mitotic DNA damage checkpoint signaling#GO:0044773;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;meiosis I#GO:0007127;negative regulation of cell cycle phase transition#GO:1901988;meiotic cell cycle process#GO:1903046;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;DNA-templated DNA replication#GO:0006261;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of mitotic cell cycle#GO:0045930;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;endonuclease complex#GO:1905348 LEPOC|Ensembl=ENSLOCG00000001483.1|UniProtKB=W5LZZ2 W5LZZ2 PTHR22590:SF3 MYOSIN MOTOR DOMAIN-CONTAINING PROTEIN IQ DOMAIN-CONTAINING PROTEIN E LEPOC|Ensembl=ENSLOCG00000004395.1|UniProtKB=W5MA40 W5MA40 PTHR17550:SF7 E3 UBIQUITIN-PROTEIN LIGASE TTC3 RNA-BINDING PROTEIN 44 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001082.1|UniProtKB=W5LYL4 W5LYL4 PTHR44321:SF1 TRANSDUCIN BETA-LIKE PROTEIN 2 TRANSDUCIN BETA-LIKE PROTEIN 2 response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000001099.1|UniProtKB=W5LYN2 W5LYN2 PTHR19282:SF440 TETRASPANIN RETINAL OUTER SEGMENT MEMBRANE PROTEIN 1A cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013975.1|UniProtKB=W5N9C3 W5N9C3 PTHR11972:SF58 NADPH OXIDASE NADPH OXIDASE 5 catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 cellular process#GO:0009987;metabolic process#GO:0008152;response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;defense response#GO:0006952;response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000001749.1|UniProtKB=W5M0V9 W5M0V9 PTHR16161:SF0 TRANSCRIPTIONAL PROTEIN SWT1 TRANSCRIPTIONAL PROTEIN SWT1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nuclear mRNA surveillance#GO:0071028;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000010020.1|UniProtKB=W5MV92 W5MV92 PTHR46708:SF8 TENASCIN FIBRONECTIN carbohydrate derivative binding#GO:0097367;binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178 cell junction assembly#GO:0034329;cell-substrate junction assembly#GO:0007044;cellular component organization#GO:0016043;circulatory system development#GO:0072359;cell junction organization#GO:0034330;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;heart development#GO:0007507;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell-substrate junction organization#GO:0150115;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Fibronectin#P00939 LEPOC|Ensembl=ENSLOCG00000013018.1|UniProtKB=W5N5X9 W5N5X9 PTHR44329:SF314 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RECEPTOR-INTERACTING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008225.1|UniProtKB=W5MNM6 W5MNM6 PTHR24404:SF55 ZINC FINGER PROTEIN ZINC FINGER PROTEIN PEGASUS cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014881.1|UniProtKB=W5NCG6 W5NCG6 PTHR13410:SF9 PROTEIN PBDC1 PROTEIN PBDC1 gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000010231.1|UniProtKB=W5MVX0 W5MVX0 PTHR23244:SF503 KELCH REPEAT DOMAIN RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS regionalization#GO:0003002;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organism development#GO:0007275;left/right pattern formation#GO:0060972;developmental process#GO:0032502;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;cell communication#GO:0007154;pattern specification process#GO:0007389 LEPOC|Ensembl=ENSLOCG00000014812.1|UniProtKB=W5NC79 W5NC79 PTHR24058:SF46 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 4 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014001.1|UniProtKB=W5N9F0 W5N9F0 PTHR24073:SF653 DRAB5-RELATED RAS-RELATED PROTEIN RAB-43 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000015387.1|UniProtKB=W5NE74 W5NE74 PTHR10176:SF1 GLYCOGEN SYNTHASE GLYCOGEN [STARCH] SYNTHASE, LIVER glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;glucan biosynthetic process#GO:0009250;polysaccharide biosynthetic process#GO:0000271;energy reserve metabolic process#GO:0006112;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;glycogen biosynthetic process#GO:0005978;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Glycogen synthase D#P00709 LEPOC|Ensembl=ENSLOCG00000003575.1|UniProtKB=W5M781 W5M781 PTHR14110:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;mitochondrial transport#GO:0006839;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;mitochondrial protein import pathway#GO:7770058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008463.1|UniProtKB=W5MPJ2 W5MPJ2 PTHR24035:SF136 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 10 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular component organization#GO:0016043;cellular process#GO:0009987;endocytosis#GO:0006897;cell migration#GO:0016477;cell motility#GO:0048870;membrane organization#GO:0061024;phagocytosis#GO:0006909;transport#GO:0006810;membrane invagination#GO:0010324;import into cell#GO:0098657;establishment of localization#GO:0051234;phagocytosis, engulfment#GO:0006911;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;apoptotic cell clearance#GO:0043277 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000012546.1|UniProtKB=W5N491 W5N491 PTHR10336:SF85 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN PHOSPHOINOSITIDE PHOSPHOLIPASE C glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;lipase activity#GO:0016298;hydrolase activity#GO:0016787 cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;cell communication#GO:0007154 phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004011.1|UniProtKB=W5M8T4 W5M8T4 PTHR11551:SF14 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 6 binding#GO:0005488;protein binding#GO:0005515;growth factor binding#GO:0019838 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012412.1|UniProtKB=W5N3S9 W5N3S9 PTHR11774:SF6 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA catalytic activity#GO:0003824;transferase activity#GO:0016740;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494 acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000010963.1|UniProtKB=W5MYJ2 W5MYJ2 PTHR19325:SF569 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT COMPONENT 4 BINDING PROTEIN, SECRETORY-RELATED complement component#PC00078;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017574.1|UniProtKB=W5NM20 W5NM20 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016450.1|UniProtKB=W5NI63 W5NI63 PTHR45740:SF15 POLY [ADP-RIBOSE] POLYMERASE SI:CH73-252I11.1 catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000003656.1|UniProtKB=W5M7J0 W5M7J0 PTHR22705:SF0 ZINC FINGER, ZZ DOMAIN CONTAINING 3 ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003140.1|UniProtKB=W5M5N9 W5M5N9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007617.1|UniProtKB=W5MLI0 W5MLI0 PTHR24020:SF14 COLLAGEN ALPHA MATRILIN-4 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000005664.1|UniProtKB=W5MEN9 W5MEN9 PTHR16001:SF6 ANGEL WING family ECTO-NOX DISULFIDE-THIOL EXCHANGER 1 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016925.1|UniProtKB=W5NJW2 W5NJW2 PTHR11937:SF487 ACTIN ACTIN-LIKE PROTEIN 6A structural molecule activity#GO:0005198;chromatin binding#GO:0003682;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200 chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 nucleus#GO:0005634;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039 LEPOC|Ensembl=ENSLOCG00000008453.1|UniProtKB=W5MPH4 W5MPH4 PTHR10902:SF0 60S RIBOSOMAL PROTEIN L35A LARGE RIBOSOMAL SUBUNIT PROTEIN EL33 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000006336.1|UniProtKB=W5MH10 W5MH10 PTHR11533:SF239 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 2 exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235 peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;proteolysis#GO:0006508;metabolic process#GO:0008152;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006077.1|UniProtKB=W5MG31 W5MG31 PTHR11006:SF51 PROTEIN ARGININE N-METHYLTRANSFERASE HISTONE-ARGININE METHYLTRANSFERASE CARM1 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001174.1|UniProtKB=W5LYW2 W5LYW2 PTHR37996:SF1 B- AND T-LYMPHOCYTE ATTENUATOR B- AND T-LYMPHOCYTE ATTENUATOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000003153.1|UniProtKB=W5M5R5 W5M5R5 PTHR11006:SF4 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 7 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;histone modifying activity#GO:0140993;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014149.1|UniProtKB=W5N9X0 W5N9X0 PTHR45664:SF11 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;pattern specification process#GO:0007389;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;skeletal system morphogenesis#GO:0048705;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;skeletal system development#GO:0001501;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;embryo development#GO:0009790 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000017792.1|UniProtKB=W5NMN7 W5NMN7 PTHR12002:SF4 CLAUDIN CLAUDIN-34 cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000004307.1|UniProtKB=W5M9U1 W5M9U1 PTHR23288:SF4 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;positive regulation of biosynthetic process#GO:0009891;snRNA metabolic process#GO:0016073;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;biosynthetic process#GO:0009058;positive regulation of RNA biosynthetic process#GO:1902680;cell-cell junction organization#GO:0045216;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of DNA-templated transcription, elongation#GO:0032786;snRNA transcription#GO:0009301;regulation of transcription by RNA polymerase II#GO:0006357;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;gene expression#GO:0010467;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;nucleobase-containing compound biosynthetic process#GO:0034654;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 tight junction#GO:0070160;cell junction#GO:0030054;nuclear protein-containing complex#GO:0140513;apical part of cell#GO:0045177;apical junction complex#GO:0043296;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;bicellular tight junction#GO:0005923;plasma membrane region#GO:0098590;nucleus#GO:0005634;cell periphery#GO:0071944;membrane-enclosed lumen#GO:0031974;cell-cell junction#GO:0005911;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;vesicle#GO:0031982;organelle lumen#GO:0043233;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000002735.1|UniProtKB=W5M4A9 W5M4A9 PTHR18966:SF397 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3A signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;voltage-gated monoatomic ion channel activity#GO:0005244;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;molecular transducer activity#GO:0060089;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276 cell surface receptor signaling pathway#GO:0007166;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cell junction#GO:0030054;synaptic membrane#GO:0097060;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NR3#P01009;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Huntington disease#P00029>NMDA receptor#P00778;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071 LEPOC|Ensembl=ENSLOCG00000008248.1|UniProtKB=W5MNQ2 W5MNQ2 PTHR45864:SF4 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 3 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488;actin binding#GO:0003779 regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 LEPOC|Ensembl=ENSLOCG00000012035.1|UniProtKB=W5N2E3 W5N2E3 PTHR11866:SF8 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP2 SUBTYPE transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological quality#GO:0065008;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to alcohol#GO:0097305;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to alcohol#GO:0097306;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;biological regulation#GO:0065007;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 LEPOC|Ensembl=ENSLOCG00000004893.1|UniProtKB=W5MBY4 W5MBY4 PTHR11566:SF32 DYNAMIN DYNAMIN-1 hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;microtubule binding#GO:0008017;GTPase activity#GO:0003924;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity#GO:0016787 synaptic vesicle transport#GO:0048489;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;synaptic vesicle localization#GO:0097479;membrane organization#GO:0061024;establishment of vesicle localization#GO:0051650;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488;endocytosis#GO:0006897;establishment of organelle localization#GO:0051656;organelle localization#GO:0051640;cellular localization#GO:0051641;localization#GO:0051179 microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;cytoskeleton#GO:0005856;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630 membrane traffic protein#PC00150 Gonadotropin-releasing hormone receptor pathway#P06664>Dnm1#P06781;CCKR signaling map#P06959>Dynamin#P07100 LEPOC|Ensembl=ENSLOCG00000013000.1|UniProtKB=W5N5U9 W5N5U9 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 primary metabolic process#GO:0044238;aminoglycan biosynthetic process#GO:0006023;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000013237.1|UniProtKB=W5N6P3 W5N6P3 PTHR15907:SF107 DUF614 FAMILY PROTEIN-RELATED PLAC8 ONZIN-RELATED PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000005241.1|UniProtKB=W5MD54 W5MD54 PTHR19288:SF92 4-NITROPHENYLPHOSPHATASE-RELATED PHOSPHOGLYCOLATE PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006301.1|UniProtKB=W5MGY0 W5MGY0 PTHR10241:SF19 LETHAL 2 GIANT LARVAE PROTEIN SYNTAXIN-BINDING PROTEIN 5-LIKE protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;syntaxin binding#GO:0019905;binding#GO:0005488;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;SNARE binding#GO:0000149;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092 export from cell#GO:0140352;Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;exocytosis#GO:0006887;secretion by cell#GO:0032940;post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport to the plasma membrane#GO:0098876;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;cellular localization#GO:0051641;localization within membrane#GO:0051668;Golgi vesicle transport#GO:0048193;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000012120.1|UniProtKB=W5N2Q6 W5N2Q6 PTHR11177:SF188 CHITINASE ACIDIC MAMMALIAN CHITINASE catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000017554.1|UniProtKB=W5NM00 W5NM00 PTHR48153:SF3 UFM1-SPECIFIC PROTEASE 2 UFM1-SPECIFIC PROTEASE 1 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 LEPOC|Ensembl=ENSLOCG00000003949.1|UniProtKB=W5M8L4 W5M8L4 PTHR46900:SF4 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 FERM AND PDZ DOMAIN CONTAINING 2 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000008261.1|UniProtKB=W5MNS2 W5MNS2 PTHR22957:SF215 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 10A enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000017124.1|UniProtKB=W5NKK1 W5NKK1 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011051.1|UniProtKB=W5MYV8 W5MYV8 PTHR18834:SF2 STEROID RECEPTOR RNA ACTIVATOR 1 STEROID RECEPTOR RNA ACTIVATOR 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000014226.1|UniProtKB=W5NA59 W5NA59 PTHR13159:SF0 RADIAL SPOKEHEAD-RELATED RADIAL SPOKE HEAD COMPONENT 4A microtubule bundle formation#GO:0001578;cilium movement#GO:0003341;organelle assembly#GO:0070925;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000013388.1|UniProtKB=W5N793 W5N793 PTHR10438:SF475 THIOREDOXIN THIOREDOXIN disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 LEPOC|Ensembl=ENSLOCG00000005607.1|UniProtKB=W5MEG0 W5MEG0 PTHR24330:SF8 HOMEOBOX PROTEIN BARH-LIKE BARH-LIKE 1 HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000003703.1|UniProtKB=W5M7P4 W5M7P4 PTHR10845:SF277 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 20 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000013061.1|UniProtKB=W5N637 W5N637 PTHR13817:SF106 TITIN PALLADIN structural molecule activity#GO:0005198 striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 contractile muscle fiber#GO:0043292;A band#GO:0031672;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;M band#GO:0031430;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005974.1|UniProtKB=W5MFR4 W5MFR4 PTHR22957:SF467 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 12 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of autophagosome assembly#GO:2000785;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;autophagosome#GO:0005776 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000003435.1|UniProtKB=W5M6R3 W5M6R3 PTHR21055:SF3 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000000891.1|UniProtKB=W5LXY8 W5LXY8 PTHR11669:SF5 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular process#GO:0009987;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 LEPOC|Ensembl=ENSLOCG00000015340.1|UniProtKB=W5NE18 W5NE18 PTHR15352:SF3 LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1 INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 2 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017591.1|UniProtKB=W5NM37 W5NM37 PTHR13832:SF343 PROTEIN PHOSPHATASE 2C [PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000011745.1|UniProtKB=W5N1D1 W5N1D1 PTHR15360:SF2 PLATELET-DERIVED GROWTH FACTOR RECEPTOR LIKE PLATELET-DERIVED GROWTH FACTOR RECEPTOR-LIKE PROTEIN tyrosine protein kinase receptor#PC00233 LEPOC|Ensembl=ENSLOCG00000002900.1|UniProtKB=W5M4Y7 W5M4Y7 PTHR31640:SF1 TRANSMEMBRANE PROTEIN KIAA1109 BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 1 import into cell#GO:0098657;cellular localization#GO:0051641;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;localization#GO:0051179;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;synaptic vesicle recycling#GO:0036465;synaptic vesicle endocytosis#GO:0048488;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 LEPOC|Ensembl=ENSLOCG00000012913.1|UniProtKB=W5N5J6 W5N5J6 PTHR22761:SF5 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 6 endosomal transport#GO:0016197;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;multivesicular body sorting pathway#GO:0071985;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;localization#GO:0051179;cellular localization#GO:0051641;late endosome to vacuole transport#GO:0045324;membrane assembly#GO:0071709;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;nucleus#GO:0005634;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012855.1|UniProtKB=W5N5B4 W5N5B4 PTHR24394:SF60 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 5 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006822.1|UniProtKB=W5MIQ8 W5MIQ8 PTHR16505:SF8 PROTEIN LZIC PROTEIN LZIC LEPOC|Ensembl=ENSLOCG00000018337.1|UniProtKB=W5NP79 W5NP79 PTHR46280:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2 ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;endosome organization#GO:0007032;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004332.1|UniProtKB=W5M9X0 W5M9X0 PTHR45752:SF10 LEUCINE-RICH REPEAT-CONTAINING PH DOMAIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN PHOSPHATASE 2 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014725.1|UniProtKB=W5NBX2 W5NBX2 PTHR15074:SF6 METHYL-CPG-BINDING PROTEIN METHYL-CPG-BINDING PROTEIN 2 heterocyclic compound binding#GO:1901363;sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012417.1|UniProtKB=W5N3T2 W5N3T2 PTHR10709:SF17 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;cortical actin cytoskeleton organization#GO:0030866;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000009364.1|UniProtKB=W5MSQ9 W5MSQ9 PTHR10656:SF47 CELL FATE DETERMINING PROTEIN MAB21-RELATED NUCLEOTIDYLTRANSFERASE MB21D2 nucleotidyltransferase#PC00174;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007616.1|UniProtKB=W5MLH8 W5MLH8 PTHR11267:SF28 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heart morphogenesis#GO:0003007;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;pattern specification process#GO:0007389;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;circulatory system development#GO:0072359;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;heart development#GO:0007507;cellular process#GO:0009987;animal organ development#GO:0048513;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;cell fate specification#GO:0001708 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000002560.1|UniProtKB=W5M3P9 W5M3P9 PTHR13968:SF3 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS C1_C2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001764.1|UniProtKB=W5M0Y3 W5M0Y3 PTHR10026:SF43 CYCLIN CYCLIN-T2 kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription elongation#GO:0032784;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;transferase complex#GO:1990234;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 kinase activator#PC00138;kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000003184.1|UniProtKB=W5M5V7 W5M5V7 PTHR23036:SF103 CYTOKINE RECEPTOR GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004742.1|UniProtKB=W5MBE6 W5MBE6 PTHR31826:SF3 NICALIN NICALIN regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000018358.1|UniProtKB=W5NPA0 W5NPA0 PTHR23334:SF76 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016081.1|UniProtKB=W5NGQ9 W5NGQ9 PTHR10857:SF133 COPINE COPINE-8 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 response to stimulus#GO:0050896;response to calcium ion#GO:0051592;response to chemical#GO:0042221;response to metal ion#GO:0010038;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000000821.1|UniProtKB=W5LXR2 W5LXR2 PTHR11935:SF116 BETA LACTAMASE DOMAIN THIOESTERASE PNKD-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000014995.1|UniProtKB=W5NCV6 W5NCV6 PTHR10732:SF0 40S RIBOSOMAL PROTEIN S17 SMALL RIBOSOMAL SUBUNIT PROTEIN ES17 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000017422.1|UniProtKB=W5NLL8 W5NLL8 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000006456.1|UniProtKB=W5MHE1 W5MHE1 PTHR18034:SF3 CELL CYCLE CONTROL PROTEIN CWF22-RELATED PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010759.1|UniProtKB=W5MXT9 W5MXT9 PTHR13258:SF0 SYNDETIN SYNDETIN binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;transport#GO:0006810;intracellular transport#GO:0046907;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013915.1|UniProtKB=W5N949 W5N949 PTHR11616:SF138 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 1 solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987 axon#GO:0030424;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000006950.1|UniProtKB=W5MJ50 W5MJ50 PTHR28646:SF1 TRANSMEMBRANE PROTEIN 201 TRANSMEMBRANE PROTEIN 201 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 microtubule-based transport#GO:0099111;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;system development#GO:0048731;cellular localization#GO:0051641;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;localization#GO:0051179;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;nuclear migration#GO:0007097;blood vessel morphogenesis#GO:0048514;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;circulatory system development#GO:0072359;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;multicellular organism development#GO:0007275;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;tube development#GO:0035295;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501 membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane#GO:0016020;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000006659.1|UniProtKB=W5MI33 W5MI33 PTHR22770:SF35 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED RANBP-TYPE AND C3HC4-TYPE ZINC FINGER-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;proteasomal protein catabolic process#GO:0010498;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of non-canonical NF-kappaB signal transduction#GO:1901222 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016205.1|UniProtKB=W5NH65 W5NH65 PTHR15073:SF4 MICROTUBULE-ASSOCIATED PROTEIN ENSCONSIN regulation of biological process#GO:0050789;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000007669.1|UniProtKB=W5MLP6 W5MLP6 PTHR13864:SF15 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 HOMOLOG-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000004629.1|UniProtKB=W5MAZ6 W5MAZ6 PTHR11630:SF75 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER MINICHROMOSOME MAINTENANCE DOMAIN-CONTAINING PROTEIN 2 helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA replication initiation#GO:0006270;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;DNA repair#GO:0006281;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;MCM complex#GO:0042555;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000009933.1|UniProtKB=W5MUT5 W5MUT5 PTHR13966:SF23 ENDONUCLEASE RELATED NUCLEASE EXOG, MITOCHONDRIAL DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788 cell death#GO:0008219;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;catabolic process#GO:0009056;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;organelle inner membrane#GO:0019866;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000001532.1|UniProtKB=W5M0D1 W5M0D1 PTHR45727:SF11 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 sterol binding#GO:0032934;small molecule binding#GO:0036094;binding#GO:0005488;cholesterol binding#GO:0015485;lipid binding#GO:0008289;steroid binding#GO:0005496;alcohol binding#GO:0043178 multicellular organismal process#GO:0032501;lipid transport#GO:0006869;digestion#GO:0007586;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;sterol transport#GO:0015918;localization#GO:0051179;system process#GO:0003008;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;chemical homeostasis#GO:0048878;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000014330.1|UniProtKB=W5NAJ3 W5NAJ3 PTHR10953:SF4 UBIQUITIN-ACTIVATING ENZYME E1 E1 UBIQUITIN-ACTIVATING ENZYME ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;catalytic activity, acting on a protein#GO:0140096 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;primary metabolic process#GO:0044238 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000012693.1|UniProtKB=W5N4R5 W5N4R5 PTHR45697:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003891.1|UniProtKB=W5M8D4 W5M8D4 PTHR46105:SF2 AGAP004733-PA NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000014844.1|UniProtKB=W5NCC6 W5NCC6 PTHR13817:SF123 TITIN L1 CELL ADHESION MOLECULE, PARALOG A structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006432.1|UniProtKB=W5MHB1 W5MHB1 PTHR45852:SF1 SER/THR-PROTEIN KINASE RIO2 SERINE_THREONINE-PROTEIN KINASE RIO2 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000004975.1|UniProtKB=W5MC78 W5MC78 PTHR24067:SF148 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 R2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016399.1|UniProtKB=W5NHZ2 W5NHZ2 PTHR46680:SF5 NF-KAPPA-B INHIBITOR ALPHA NFKB INHIBITOR EPSILON DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;protein sequestering activity#GO:0140311;transcription factor binding#GO:0008134;binding#GO:0005488;molecular sequestering activity#GO:0140313 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical NF-kappaB signal transduction#GO:0043122;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015669.1|UniProtKB=W5NF77 W5NF77 PTHR12247:SF62 POLYCOMB GROUP PROTEIN SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 2 protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000007210.1|UniProtKB=W5MK17 W5MK17 PTHR10417:SF15 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 11 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000011822.1|UniProtKB=W5N1P0 W5N1P0 PTHR45620:SF23 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON-LIKE PEPTIDE 2 RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002866.1|UniProtKB=W5M4R8 W5M4R8 PTHR10554:SF8 SYNTROPHIN BETA-2-SYNTROPHIN dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synapse#GO:0045202;plasma membrane#GO:0005886;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008635.1|UniProtKB=W5MQ41 W5MQ41 PTHR21574:SF0 CENTROSOMAL PROTEIN OF 120 KDA CENTROSOMAL PROTEIN OF 120 KDA cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000013992.1|UniProtKB=W5N9E0 W5N9E0 PTHR45636:SF13 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-9 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000015137.1|UniProtKB=W5NDB9 W5NDB9 PTHR45161:SF1 CYTOSKELETON-ASSOCIATED PROTEIN 4 CYTOSKELETON-ASSOCIATED PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;rough endoplasmic reticulum#GO:0005791;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000018283.1|UniProtKB=W5NP25 W5NP25 PTHR22750:SF19 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 6 bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004767.1|UniProtKB=W5MBG0 W5MBG0 PTHR28672:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein K11-linked ubiquitination#GO:0070979;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461 LEPOC|Ensembl=ENSLOCG00000011276.1|UniProtKB=W5MZP6 W5MZP6 PTHR21845:SF2 TRANSMEMBRANE ANCHOR PROTEIN 1 MATRIX-REMODELING-ASSOCIATED PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000011157.1|UniProtKB=W5MZA2 W5MZA2 PTHR48082:SF2 ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT ALPHA, MITOCHONDRIAL monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;ligase activity#GO:0016874;ribonucleotide binding#GO:0032553;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;ATP binding#GO:0005524 ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;organophosphate biosynthetic process#GO:0090407;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165 proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259 primary active transporter#PC00068;ATP synthase#PC00002 ATP synthesis#P02721>F1 alpha#P02791 LEPOC|Ensembl=ENSLOCG00000012738.1|UniProtKB=W5N4W8 W5N4W8 PTHR13158:SF5 FAMILY NOT NAMED NAD KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleotide metabolic process#GO:0006163;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524 LEPOC|Ensembl=ENSLOCG00000005905.1|UniProtKB=W5MFH5 W5MFH5 PTHR23176:SF103 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 9 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000013109.1|UniProtKB=W5N688 W5N688 PTHR46260:SF2 RING-TYPE DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 8B mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton-dependent cytokinesis#GO:0061640;organelle fission#GO:0048285;mitotic cytokinetic process#GO:1902410;cytokinetic process#GO:0032506;nuclear division#GO:0000280;cytokinesis#GO:0000910;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;cell cycle process#GO:0022402;cell division#GO:0051301;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;midbody#GO:0030496 LEPOC|Ensembl=ENSLOCG00000011510.1|UniProtKB=W5N0I6 W5N0I6 PTHR10414:SF27 ETHANOLAMINEPHOSPHOTRANSFERASE CHOLINE_ETHANOLAMINEPHOSPHOTRANSFERASE 1 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000013822.1|UniProtKB=W5N8U7 W5N8U7 PTHR47969:SF15 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microtubule motor activity#GO:0003777;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 organelle organization#GO:0006996;cellular process#GO:0009987;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization involved in mitosis#GO:1902850;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization#GO:0000226 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000017174.1|UniProtKB=W5NKS7 W5NKS7 PTHR13800:SF6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 4 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;ligand-gated monoatomic ion channel activity#GO:0015276;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017515.1|UniProtKB=W5NLW1 W5NLW1 PTHR11711:SF137 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4D small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000012839.1|UniProtKB=W5N5C0 W5N5C0 PTHR23175:SF5 PDZ DOMAIN-CONTAINING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 23 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 LEPOC|Ensembl=ENSLOCG00000003676.1|UniProtKB=W5M7N0 W5M7N0 PTHR45713:SF8 FTP DOMAIN-CONTAINING PROTEIN SI:CH211-215K15.4 LEPOC|Ensembl=ENSLOCG00000020986.1|UniProtKB=Q8HQM9 Q8HQM9 PTHR39937:SF1 ATP SYNTHASE PROTEIN 8 ATP SYNTHASE F(0) COMPLEX SUBUNIT 8 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017359.1|UniProtKB=W5NLF5 W5NLF5 PTHR13447:SF2 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN BS1M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007218.1|UniProtKB=W5MK39 W5MK39 PTHR10845:SF42 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 5 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519 cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 LEPOC|Ensembl=ENSLOCG00000001791.1|UniProtKB=W5M114 W5M114 PTHR47978:SF65 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-26 ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of secretion#GO:0051046;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530 intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000005867.1|UniProtKB=W5MFC6 W5MFC6 PTHR19226:SF2 THY-1 MEMBRANE GLYCOPROTEIN THY-1 MEMBRANE GLYCOPROTEIN enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cell surface receptor signaling pathway#GO:0007166;regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cell communication#GO:0007154;regulation of cell-matrix adhesion#GO:0001952;positive regulation of cellular component organization#GO:0051130;regulation of cell junction assembly#GO:1901888;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-substrate adhesion#GO:0010811;integrin-mediated signaling pathway#GO:0007229 side of membrane#GO:0098552;membrane microdomain#GO:0098857;external side of plasma membrane#GO:0009897;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane raft#GO:0045121;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015967.1|UniProtKB=W5NGA3 W5NGA3 PTHR11438:SF2 PROENKEPHALIN PREPRONOCICEPTIN G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;sensory perception of pain#GO:0019233;chemical synaptic transmission#GO:0007268;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008 cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;neuronal cell body#GO:0043025;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;cell body#GO:0044297;cell junction#GO:0030054;synaptic membrane#GO:0097060 neuropeptide#PC00162;peptide hormone#PC00179;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014048.1|UniProtKB=W5N9K5 W5N9K5 PTHR12608:SF1 TRANSMEMBRANE PROTEIN HTP-1 RELATED DIVALENT CATION_PROTON ANTIPORTER TMEM165-RELATED transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 calcium ion homeostasis#GO:0055074;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000010829.1|UniProtKB=W5MY20 W5MY20 PTHR10953:SF4 UBIQUITIN-ACTIVATING ENZYME E1 E1 UBIQUITIN-ACTIVATING ENZYME ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;response to stress#GO:0006950 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 LEPOC|Ensembl=ENSLOCG00000017241.1|UniProtKB=W5NL16 W5NL16 PTHR24418:SF94 TYROSINE-PROTEIN KINASE PROTEIN-TYROSINE KINASE 2-BETA catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;non-membrane spanning protein tyrosine kinase activity#GO:0004715 epidermal growth factor receptor signaling pathway#GO:0007173;regulation of cell adhesion#GO:0030155;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;positive regulation of cell migration#GO:0030335;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of locomotion#GO:0040017;cell surface receptor signaling pathway#GO:0007166;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell motility#GO:2000147;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 Integrin signalling pathway#P00034>FAK#P00932;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PYK2#P00852;Gonadotropin-releasing hormone receptor pathway#P06664>Pyk2#P06730;CCKR signaling map#P06959>FAK2#P07218 LEPOC|Ensembl=ENSLOCG00000003798.1|UniProtKB=W5M835 W5M835 PTHR12656:SF12 BRG-1 ASSOCIATED FACTOR 250 BAF250 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1A protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;chromatin binding#GO:0003682;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000012198.1|UniProtKB=W5N300 W5N300 PTHR11960:SF14 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E nucleic acid binding#GO:0003676;binding#GO:0005488;translation factor activity#GO:0180051;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 CCKR signaling map#P06959>EIF4E#P07094;p38 MAPK pathway#P05918>eIF4E#P06024 LEPOC|Ensembl=ENSLOCG00000008273.1|UniProtKB=W5MNV0 W5MNV0 PTHR10353:SF10 GLYCOSYL HYDROLASE KLOTHO glucosidase activity#GO:0015926;binding#GO:0005488;signaling receptor binding#GO:0005102;hydrolase activity#GO:0016787;protein binding#GO:0005515;growth factor binding#GO:0019838;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;growth factor receptor binding#GO:0070851;beta-glucosidase activity#GO:0008422;catalytic activity#GO:0003824;fibroblast growth factor binding#GO:0017134;hydrolase activity, acting on glycosyl bonds#GO:0016798;fibroblast growth factor receptor binding#GO:0005104 cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;signal transduction#GO:0007165;fibroblast growth factor receptor signaling pathway#GO:0008543;biological regulation#GO:0065007;response to fibroblast growth factor#GO:0071774;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363 metabolite interconversion enzyme#PC00262;glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015097.1|UniProtKB=W5ND75 W5ND75 PTHR11607:SF57 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2X hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010195.1|UniProtKB=W5MVS1 W5MVS1 PTHR24412:SF433 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 8 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004185.1|UniProtKB=W5M9D5 W5M9D5 PTHR22913:SF4 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 1 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;aminoglycan metabolic process#GO:0006022;polysaccharide biosynthetic process#GO:0000271;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glycosaminoglycan metabolic process#GO:0030203;cellular component organization#GO:0016043;aminoglycan biosynthetic process#GO:0006023;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;glycosaminoglycan biosynthetic process#GO:0006024;metabolic process#GO:0008152;extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009456.1|UniProtKB=W5MT38 W5MT38 PTHR20955:SF4 PROTEIN JAGUNAL HOMOLOG 1 PROTEIN JAGUNAL HOMOLOG 1 vesicle-mediated transport#GO:0016192;response to chemical#GO:0042221;response to cytokine#GO:0034097;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;localization#GO:0051179;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012612.1|UniProtKB=W5N4G6 W5N4G6 PTHR14388:SF5 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 4A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006441.1|UniProtKB=W5MHC2 W5MHC2 PTHR24068:SF36 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D1 aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 macromolecule catabolic process#GO:0009057;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000005709.1|UniProtKB=W5MET7 W5MET7 PTHR10133:SF64 DNA POLYMERASE I DNA POLYMERASE THETA transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000016202.1|UniProtKB=W5NH61 W5NH61 PTHR23026:SF129 NADPH NITROREDUCTASE IODOTYROSINE DEIODINASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000012135.1|UniProtKB=W5N2R9 W5N2R9 PTHR11849:SF181 ETS ETS TRANSLOCATION VARIANT 4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016261.1|UniProtKB=W5NHE5 W5NHE5 PTHR10334:SF602 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLI PATHOSIS RELATED 1 LIKE 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010088.1|UniProtKB=W5MVD0 W5MVD0 PTHR14320:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 LEPOC|Ensembl=ENSLOCG00000003033.1|UniProtKB=W5M5C3 W5M5C3 PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA phospholipid binding#GO:0005543;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;small molecule binding#GO:0036094;ion binding#GO:0043167;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;cation binding#GO:0043169;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289 organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;lipid metabolic process#GO:0006629;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 LEPOC|Ensembl=ENSLOCG00000017833.1|UniProtKB=W5NMS7 W5NMS7 PTHR11079:SF156 CYTOSINE DEAMINASE FAMILY MEMBER TRNA-SPECIFIC ADENOSINE-34 DEAMINASE REGULATORY SUBUNIT ADAT3 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;deaminase#PC00088;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008017.1|UniProtKB=W5MMX7 W5MMX7 PTHR14275:SF0 PROMETHIN LIPID DROPLET ASSEMBLY FACTOR 1 LEPOC|Ensembl=ENSLOCG00000008471.1|UniProtKB=W5MPJ9 W5MPJ9 PTHR24161:SF21 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 35 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015732.1|UniProtKB=W5NFF8 W5NFF8 PTHR24261:SF13 PLASMINOGEN-RELATED PLASMINOGEN binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;negative regulation of hemostasis#GO:1900047;negative regulation of coagulation#GO:0050819;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;regulation of wound healing#GO:0061041;negative regulation of blood coagulation#GO:0030195;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;negative regulation of response to wounding#GO:1903035;macromolecule metabolic process#GO:0043170;negative regulation of wound healing#GO:0061045;regulation of response to wounding#GO:1903034;regulation of hemostasis#GO:1900046;cellular process#GO:0009987;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of coagulation#GO:0050818;fibrinolysis#GO:0042730;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein modifying enzyme#PC00260;serine protease#PC00203 Blood coagulation#P00011>Plasmin#P00415;Blood coagulation#P00011>Plasminogen#P00408;Plasminogen activating cascade#P00050>Plasminogen#P01255;Plasminogen activating cascade#P00050>Plasmin#P01246 LEPOC|Ensembl=ENSLOCG00000005946.1|UniProtKB=W5MFM3 W5MFM3 PTHR24243:SF9 G-PROTEIN COUPLED RECEPTOR NEUROTENSIN RECEPTOR TYPE 1 neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011153.1|UniProtKB=W5MZ95 W5MZ95 PTHR21228:SF9 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000005062.1|UniProtKB=W5MCI6 W5MCI6 PTHR45623:SF20 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD7 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;histone binding#GO:0042393;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;DNA binding#GO:0003677 animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;inner ear morphogenesis#GO:0042472;cellular process#GO:0009987;heart development#GO:0007507;embryo development#GO:0009790;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;ear development#GO:0043583;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;sensory organ morphogenesis#GO:0090596;central nervous system development#GO:0007417;circulatory system development#GO:0072359;chromatin remodeling#GO:0006338;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;inner ear development#GO:0048839;regulation of macromolecule biosynthetic process#GO:0010556;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;chromatin organization#GO:0006325;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;anatomical structure development#GO:0048856;system development#GO:0048731;heart morphogenesis#GO:0003007;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000011723.1|UniProtKB=W5N1B0 W5N1B0 PTHR24361:SF656 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;FGF signaling pathway#P00021>MEKK1-5#P00634;B cell activation#P00010>MEKK#P00369;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;Integrin signalling pathway#P00034>ERK#P00907 LEPOC|Ensembl=ENSLOCG00000006356.1|UniProtKB=W5MH18 W5MH18 PTHR11599:SF144 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA-TYPE 8 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 proteasome complex#GO:0000502;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000010480.1|UniProtKB=W5MWT8 W5MWT8 PTHR15510:SF5 SPERM-ASSOCIATED ANTIGEN 8 SPERM-ASSOCIATED ANTIGEN 8 microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;flagellated sperm motility#GO:0030317;reproductive process#GO:0022414;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cellular process#GO:0009987;sperm motility#GO:0097722;cilium movement involved in cell motility#GO:0060294 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;microtubule#GO:0005874;cilium#GO:0005929;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881 LEPOC|Ensembl=ENSLOCG00000009259.1|UniProtKB=W5MSD4 W5MSD4 PTHR16181:SF34 PROTEIN FAM83A-RELATED PROTEIN FAM83A protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;cellular response to stimulus#GO:0051716 LEPOC|Ensembl=ENSLOCG00000003793.1|UniProtKB=W5M820 W5M820 AK1 PTHR23359:SF70 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 1 transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 LEPOC|Ensembl=ENSLOCG00000003289.1|UniProtKB=W5M674 W5M674 PTHR12416:SF3 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000011236.1|UniProtKB=W5MZJ4 W5MZJ4 PTHR12107:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;channel regulator activity#GO:0016247 regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;transmission of nerve impulse#GO:0019226;system process#GO:0003008;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051;nervous system process#GO:0050877;localization within membrane#GO:0051668;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;localization#GO:0051179;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804 synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;postsynapse#GO:0098794;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226 transporter#PC00227;ion channel#PC00133;voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>stargazin#P00998 LEPOC|Ensembl=ENSLOCG00000008649.1|UniProtKB=W5MQ54 W5MQ54 PTHR12788:SF6 PROTEIN-TYROSINE SULFOTRANSFERASE 2 PROTEIN-TYROSINE SULFOTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity, acting on a protein#GO:0140096 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000003411.1|UniProtKB=W5M6N0 W5M6N0 PTHR14564:SF2 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT MIC26 membrane organization#GO:0061024;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800 LEPOC|Ensembl=ENSLOCG00000012111.1|UniProtKB=W5N2P6 W5N2P6 SPDL1 PTHR32123:SF9 BICD FAMILY-LIKE CARGO ADAPTER PROTEIN SPINDLY binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;nuclear division#GO:0000280;spindle localization#GO:0051653;cellular localization#GO:0051641;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;establishment of organelle localization#GO:0051656;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;mitotic metaphase chromosome alignment#GO:0007080;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;establishment of spindle localization#GO:0051293;macromolecule localization#GO:0033036;mitotic sister chromatid segregation#GO:0000070;protein localization to kinetochore#GO:0034501 outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005287.1|UniProtKB=W5MDB7 W5MDB7 PTHR24223:SF10 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 12 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000009447.1|UniProtKB=W5MT26 W5MT26 PTHR11647:SF50 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;dihydropyrimidinase activity#GO:0004157 pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 LEPOC|Ensembl=ENSLOCG00000011013.1|UniProtKB=W5MYQ5 W5MYQ5 PTHR13354:SF8 ROUND SPERMATID BASIC PROTEIN 1 LYSINE-SPECIFIC DEMETHYLASE 9 histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003873.1|UniProtKB=W5M8C4 W5M8C4 PTHR16059:SF16 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015584.1|UniProtKB=W5NEX7 W5NEX7 PTHR13285:SF20 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE HHAT palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;protein modification process#GO:0036211;primary metabolic process#GO:0044238 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000012665.1|UniProtKB=W5N4N1 W5N4N1 PTHR13045:SF17 5'-NUCLEOTIDASE 5'-NUCLEOTIDASE hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 esterase#PC00097;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014717.1|UniProtKB=W5NBV7 W5NBV7 PTHR15151:SF2 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 multicellular organismal-level homeostasis#GO:0048871;positive regulation of leukocyte proliferation#GO:0070665;multicellular organismal process#GO:0032501;regulation of lymphocyte proliferation#GO:0050670;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of cell population proliferation#GO:0042127;positive regulation of lymphocyte activation#GO:0051251;positive regulation of lymphocyte proliferation#GO:0050671;homeostasis of number of cells#GO:0048872;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of B cell proliferation#GO:0030890;homeostatic process#GO:0042592;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;regulation of B cell proliferation#GO:0030888;positive regulation of leukocyte activation#GO:0002696;regulation of multicellular organismal process#GO:0051239;lymphocyte homeostasis#GO:0002260;positive regulation of immune system process#GO:0002684;regulation of B cell activation#GO:0050864;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of biological process#GO:0048518;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of lymphocyte activation#GO:0051249;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013525.1|UniProtKB=W5N7R8 W5N7R8 PTHR23113:SF230 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR-LIKE 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000016879.1|UniProtKB=W5NJQ7 W5NJQ7 PTHR12874:SF29 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 9 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000018128.1|UniProtKB=W5NNM0 W5NNM0 PTHR11984:SF52 CONNEXIN GAP JUNCTION GAMMA-2 PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell junction#GO:0030054 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000009719.1|UniProtKB=W5MU50 W5MU50 PTHR24023:SF912 COLLAGEN ALPHA COLLAGEN ALPHA-1(XV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000015143.1|UniProtKB=W5NDD0 W5NDD0 PTHR45682:SF8 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 26 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000000190.1|UniProtKB=W5LVS7 W5LVS7 PTHR23411:SF36 TAPASIN IMMUNOGLOBULIN KAPPA CONSTANT immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010770.1|UniProtKB=W5MXT1 W5MXT1 PTHR33668:SF3 PROTEIN BRICK1 PROTEIN BRICK1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 regulation of biological quality#GO:0065008;regulation of cell projection assembly#GO:0060491;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;positive regulation of cell projection organization#GO:0031346;regulation of cytoskeleton organization#GO:0051493;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure size#GO:0090066;regulation of cell projection organization#GO:0031344;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012514.1|UniProtKB=W5N463 W5N463 PTHR11801:SF2 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 interleukin-9-mediated signaling pathway#GO:0038113;cell surface receptor signaling pathway via STAT#GO:0097696;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;response to hormone#GO:0009725;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;cellular response to peptide hormone stimulus#GO:0071375;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;interleukin-2-mediated signaling pathway#GO:0038110;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cytokine-mediated signaling pathway#GO:0019221 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Interleukin signaling pathway#P00036>STAT#P00996;CCKR signaling map#P06959>STAT3#P07165;Ras Pathway#P04393>Stat 1/3#P04566;Gonadotropin-releasing hormone receptor pathway#P06664>STAT3#P06795;PDGF signaling pathway#P00047>STAT#P01173;EGF receptor signaling pathway#P00018>STAT#P00561;Angiogenesis#P00005>STAT3#P00217;JAK/STAT signaling pathway#P00038>STAT#P01027;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832 LEPOC|Ensembl=ENSLOCG00000014153.1|UniProtKB=W5N9X5 W5N9X5 PTHR31184:SF2 HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER HUNTINGTIN-INTERACTING PROTEIN K regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;negative regulation of programmed cell death#GO:0043069;regulation of protein stability#GO:0031647;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000001751.1|UniProtKB=W5M0W6 W5M0W6 PTHR23244:SF462 KELCH REPEAT DOMAIN KELCH REPEAT-CONTAINING PROTEIN ISOFORM X1 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 LEPOC|Ensembl=ENSLOCG00000003780.1|UniProtKB=W5M818 W5M818 PTHR11733:SF133 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003499.1|UniProtKB=W5M6Y2 W5M6Y2 PTHR12993:SF11 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;deacylase activity#GO:0160215;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 deacetylase#PC00087 LEPOC|Ensembl=ENSLOCG00000013268.1|UniProtKB=W5N6U2 W5N6U2 PTHR23320:SF143 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED SUBFAMILY NOT NAMED transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004661.1|UniProtKB=W5MB17 W5MB17 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 519 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000007438.1|UniProtKB=W5ML03 W5ML03 PTHR45623:SF22 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD4 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;DNA binding#GO:0003677;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;histone binding#GO:0042393;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017112.1|UniProtKB=W5NKI6 W5NKI6 PTHR32261:SF4 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 6 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000000578.1|UniProtKB=W5LWY2 W5LWY2 PTHR45615:SF13 MYOSIN HEAVY CHAIN, NON-MUSCLE UNCONVENTIONAL MYOSIN-XVIIIA protein binding#GO:0005515;protein-containing complex binding#GO:0044877;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000012711.1|UniProtKB=W5N4T0 W5N4T0 PTHR21258:SF39 DOCKING PROTEIN RELATED FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 3 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;fibroblast growth factor receptor binding#GO:0005104;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;growth factor receptor binding#GO:0070851;signaling receptor complex adaptor activity#GO:0030159 cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;cell surface receptor signaling pathway#GO:0007166;response to fibroblast growth factor#GO:0071774;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>FRS-2#P00240;FGF signaling pathway#P00021>FRS2#P00635 LEPOC|Ensembl=ENSLOCG00000016022.1|UniProtKB=W5NGH5 W5NGH5 PTHR44858:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 6 TETRATRICOPEPTIDE REPEAT DOMAIN 6 LEPOC|Ensembl=ENSLOCG00000011450.1|UniProtKB=W5N0A9 W5N0A9 PTHR12062:SF1 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi stack#GO:0005795;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000005268.1|UniProtKB=W5MD85 W5MD85 PTHR31200:SF1 INO80 COMPLEX SUBUNIT C INO80 COMPLEX SUBUNIT C cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840 Ino80 complex#GO:0031011;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000001708.1|UniProtKB=W5M0R0 W5M0R0 PTHR24231:SF35 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002002.1|UniProtKB=W5M1S0 W5M1S0 PTHR22804:SF6 AGGRECAN/VERSICAN PROTEOGLYCAN VERSICAN CORE PROTEIN animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;system development#GO:0048731;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 cell junction#GO:0030054;extracellular region#GO:0005576;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;external encapsulating structure#GO:0030312;membrane#GO:0016020;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000010117.1|UniProtKB=W5MVG6 W5MVG6 PTHR46040:SF4 HIGH MOBILITY GROUP PROTEIN 2 HMG BOX DOMAIN-CONTAINING PROTEIN regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000009705.1|UniProtKB=W5MTZ0 W5MTZ0 PTHR11849:SF315 ETS TRANSCRIPTION FACTOR SPI-C DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010151.1|UniProtKB=W5MVL9 W5MVL9 PTHR24406:SF4 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER PROTEIN 692 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002148.1|UniProtKB=W5M291 W5M291 PTHR24100:SF161 BUTYROPHILIN PROGRAMMED CELL DEATH 1 LIGAND 1-LIKE protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cell communication#GO:0007154;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013316.1|UniProtKB=W5N703 W5N703 PTHR24089:SF59 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER organophosphate ester transmembrane transporter activity#GO:0015605;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;quaternary ammonium group transmembrane transporter activity#GO:0015651 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;vitamin transport#GO:0051180;organophosphate ester transport#GO:0015748 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000011257.1|UniProtKB=W5MZM4 W5MZM4 PTHR11955:SF89 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, INTESTINAL organic acid binding#GO:0043177;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;lipid binding#GO:0008289;fatty acid binding#GO:0005504 lipid transport#GO:0006869;macromolecule localization#GO:0033036;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;lipid localization#GO:0010876;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000001923.1|UniProtKB=W5M1H0 W5M1H0 PTHR21346:SF2 FUN14 DOMAIN CONTAINING FUN14 DOMAIN-CONTAINING PROTEIN 1 cellular process#GO:0009987;autophagy#GO:0006914;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 LEPOC|Ensembl=ENSLOCG00000013052.1|UniProtKB=W5N615 W5N615 PTHR24410:SF12 HL07962P-RELATED BTB_POZ DOMAIN-CONTAINING PROTEIN 17 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003622.1|UniProtKB=W5M7D7 W5M7D7 PTHR21668:SF0 EIF-1A EUKARYOTIC TRANSLATION INITIATION FACTOR 4C translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000002140.1|UniProtKB=W5M298 W5M298 PTHR10366:SF816 NAD DEPENDENT EPIMERASE/DEHYDRATASE SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E MEMBER 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091;lyase#PC00144;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002818.1|UniProtKB=W5M4K7 W5M4K7 PTHR13943:SF31 HRAS-LIKE SUPPRESSOR - RELATED RETINOIC ACID RECEPTOR RESPONDER 3-RELATED transferase activity#GO:0016740;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;A2-type glycerophospholipase activity#GO:0004623;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012445.1|UniProtKB=W5N3W1 W5N3W1 PTHR24335:SF3 MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN 1 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cell differentiation#GO:0030154;central nervous system development#GO:0007417;pancreas development#GO:0031016;cell fate commitment#GO:0045165;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cellular process#GO:0009987;neuron fate commitment#GO:0048663;neurogenesis#GO:0022008;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell fate specification#GO:0001708;central nervous system neuron differentiation#GO:0021953;neuron differentiation#GO:0030182;developmental process#GO:0032502 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016308.1|UniProtKB=W5NHL9 W5NHL9 PTHR43347:SF5 ACYL-COA SYNTHETASE ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 LEPOC|Ensembl=ENSLOCG00000017873.1|UniProtKB=W5NMW7 W5NMW7 PTHR24366:SF177 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 53 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000015726.1|UniProtKB=W5NFF6 W5NFF6 PTHR24131:SF8 APOPTOSIS-STIMULATING OF P53 PROTEIN APOPTOSIS-STIMULATING OF P53 PROTEIN 2 binding#GO:0005488;protein binding#GO:0005515 apoptotic signaling pathway#GO:0097190;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;signal transduction by p53 class mediator#GO:0072331;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;programmed cell death#GO:0012501 intracellular organelle#GO:0043229;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;nucleus#GO:0005634;cell-cell junction#GO:0005911;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013454.1|UniProtKB=W5N7J0 W5N7J0 PTHR22760:SF4 GLYCOSYLTRANSFERASE GPI ALPHA-1,2-MANNOSYLTRANSFERASE 3 glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000011087.1|UniProtKB=W5MZ14 W5MZ14 PTHR11742:SF40 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IB catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009358.1|UniProtKB=W5MSS9 W5MSS9 PTHR45819:SF2 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function activator activity#GO:0140677;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000012896.1|UniProtKB=W5N5G4 W5N5G4 PTHR46065:SF1 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER RING-TYPE E3 UBIQUITIN TRANSFERASE aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004557.1|UniProtKB=W5MAQ9 W5MAQ9 PTHR14398:SF2 RNA RECOGNITION RRM/RNP DOMAIN RNA-BINDING PROTEIN 26 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003598.1|UniProtKB=W5M7B0 W5M7B0 PTHR22594:SF16 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINE--TRNA LIGASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000007254.1|UniProtKB=W5MK69 W5MK69 PTHR24409:SF319 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 438 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000004400.1|UniProtKB=W5MA71 W5MA71 PTHR21245:SF5 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN R mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015538.1|UniProtKB=W5NET0 W5NET0 PTHR24093:SF284 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;regulation of cytosolic calcium ion concentration#GO:0051480;homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000013875.1|UniProtKB=W5N902 W5N902 PTHR24040:SF3 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN SEX HORMONE-BINDING GLOBULIN lipid binding#GO:0008289;steroid binding#GO:0005496;hormone binding#GO:0042562;binding#GO:0005488 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012457.1|UniProtKB=W5N3X8 W5N3X8 PTHR22792:SF51 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007837.1|UniProtKB=W5MMA5 W5MMA5 PTHR11727:SF34 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649 nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011827.1|UniProtKB=W5N1N2 W5N1N2 PTHR47227:SF5 DNA-DIRECTED RNA POLYMERASE SUBUNIT K DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription by RNA polymerase I#GO:0006360;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 LEPOC|Ensembl=ENSLOCG00000000895.1|UniProtKB=W5LXZ1 W5LXZ1 PTHR11904:SF12 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278;organophosphate biosynthetic process#GO:0090407;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Purine metabolism#P02769>Nucleoside Phosphorylase#P03115;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248 LEPOC|Ensembl=ENSLOCG00000017439.1|UniProtKB=W5NLN5 W5NLN5 PTHR45961:SF5 IP21249P DUAL SPECIFICITY PROTEIN PHOSPHATASE 14 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000011301.1|UniProtKB=W5MZT2 W5MZT2 PTHR11610:SF13 LIPASE ENDOTHELIAL LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004218.1|UniProtKB=W5M9I6 W5M9I6 PTHR22738:SF4 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 4 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015051.1|UniProtKB=W5ND19 W5ND19 PTHR12346:SF2 SIN3B-RELATED PAIRED AMPHIPATHIC HELIX PROTEIN SIN3A transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>Sin3A#P00771;p53 pathway#P00059>Sin3#P04622 LEPOC|Ensembl=ENSLOCG00000003877.1|UniProtKB=W5M8C0 W5M8C0 PTHR22576:SF27 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE PARACASPASE 2 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000006618.1|UniProtKB=W5MHY6 W5MHY6 PTHR22980:SF0 CORTISTATIN CENTROMERE PROTEIN S chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cell cycle process#GO:0022402;DNA replication#GO:0006260;reciprocal homologous recombination#GO:0140527;homologous recombination#GO:0035825;reproductive process#GO:0022414;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;organelle fission#GO:0048285;DNA-templated DNA replication#GO:0006261;organelle organization#GO:0006996;cellular process#GO:0009987;resolution of meiotic recombination intermediates#GO:0000712;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 neuropeptide#PC00162;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000016146.1|UniProtKB=W5NGY6 W5NGY6 PTHR11654:SF91 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018075.1|UniProtKB=W5NNG7 W5NNG7 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000004976.1|UniProtKB=W5MC81 W5MC81 PTHR10241:SF21 LETHAL 2 GIANT LARVAE PROTEIN LETHAL(2) GIANT LARVAE PROTEIN HOMOLOG 1 myosin binding#GO:0017022;SNARE binding#GO:0000149;enzyme activator activity#GO:0008047;cytoskeletal protein binding#GO:0008092;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;syntaxin binding#GO:0019905;molecular function activator activity#GO:0140677 regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;Golgi to plasma membrane transport#GO:0006893;regulation of cell communication#GO:0010646;cell cycle#GO:0007049;establishment of cell polarity#GO:0030010;microtubule cytoskeleton organization#GO:0000226;secretion#GO:0046903;localization#GO:0051179;cortical actin cytoskeleton organization#GO:0030866;organelle localization#GO:0051640;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;regulation of Notch signaling pathway#GO:0008593;localization within membrane#GO:0051668;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;establishment of spindle localization#GO:0051293;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;regulation of response to stimulus#GO:0048583;transport#GO:0006810;establishment of organelle localization#GO:0051656;export from cell#GO:0140352;cellular component organization#GO:0016043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular localization#GO:0051641;spindle localization#GO:0051653;post-Golgi vesicle-mediated transport#GO:0006892;secretion by cell#GO:0032940;establishment or maintenance of cell polarity#GO:0007163;regulation of signaling#GO:0023051;regulation of establishment or maintenance of cell polarity#GO:0032878;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;exocytosis#GO:0006887;Golgi vesicle transport#GO:0048193 actin cytoskeleton#GO:0015629;membrane#GO:0016020;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000010615.1|UniProtKB=W5MXA5 W5MXA5 PTHR28570:SF18 ASPARTYL AMINOPEPTIDASE ASPARTYL AMINOPEPTIDASE exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012588.1|UniProtKB=W5N4D8 W5N4D8 PTHR24201:SF8 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR B enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914 regulation of cell cycle process#GO:0010564;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell population proliferation#GO:0008285;regulation of cell population proliferation#GO:0042127;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 p53 pathway#P00059>ARF#G01574 LEPOC|Ensembl=ENSLOCG00000005306.1|UniProtKB=W5MDE1 W5MDE1 PTHR14064:SF6 CHONDROMODULIN-RELATED LEUKOCYTE CELL-DERIVED CHEMOTAXIN 1 regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;negative regulation of cell population proliferation#GO:0008285;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of vasculature development#GO:1901342;regulation of angiogenesis#GO:0045765;regulation of cell population proliferation#GO:0042127;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of angiogenesis#GO:0016525 LEPOC|Ensembl=ENSLOCG00000009059.1|UniProtKB=W5MRN0 W5MRN0 PTHR12369:SF14 CHONDROITIN SYNTHASE CHONDROITIN POLYMERIZING FACTOR 2, NON-CATALYTIC SUBUNIT hexosyltransferase activity#GO:0016758;protein complex scaffold activity#GO:0140378;transferase activity#GO:0016740;catalytic activity#GO:0003824;structural molecule activity#GO:0005198;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000015406.1|UniProtKB=W5NE97 W5NE97 PTHR24247:SF88 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 7-RELATED neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000148.1|UniProtKB=W5LVK7 W5LVK7 PTHR13585:SF31 CHASCON, ISOFORM D-RELATED ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000012175.1|UniProtKB=W5N2W7 W5N2W7 PTHR10127:SF814 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING MEPRIN A SUBUNIT BETA metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000016090.1|UniProtKB=W5NGR5 W5NGR5 PTHR10224:SF15 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL ES1 PROTEIN, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000016088.1|UniProtKB=W5NGR3 W5NGR3 PTHR11353:SF26 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT DELTA protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000012086.1|UniProtKB=W5N2L8 W5N2L8 PTHR19932:SF10 WD REPEAT AND HMG-BOX DNA BINDING PROTEIN WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261 replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014116.1|UniProtKB=W5N9T8 W5N9T8 PTHR23101:SF58 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR 3 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001267.1|UniProtKB=W5LZD0 W5LZD0 PTHR12702:SF3 SEC15 EXOCYST COMPLEX COMPONENT 6B secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;cell periphery#GO:0071944;exocyst#GO:0000145;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001907.1|UniProtKB=W5M1E9 W5M1E9 PTHR10825:SF29 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transferase complex#GO:1990234;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000003321.1|UniProtKB=W5M6B9 W5M6B9 PTHR17490:SF16 SUA5 THREONYLCARBAMOYL-AMP SYNTHASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;binding#GO:0005488;nucleic acid binding#GO:0003676;tRNA binding#GO:0000049;RNA binding#GO:0003723 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;biological regulation#GO:0065007;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;regulation of biological quality#GO:0065008;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010235.1|UniProtKB=W5MVX6 W5MVX6 PTHR11904:SF24 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide metabolic process#GO:0009117;nucleoside catabolic process#GO:0009164;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule catabolic process#GO:0034656;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleoside metabolic process#GO:0042278;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate biosynthetic process#GO:1901293;glycosyl compound catabolic process#GO:1901658;NAD+ metabolic process#GO:0019674;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000006493.1|UniProtKB=W5MHI5 W5MHI5 PTHR12322:SF76 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;sex differentiation#GO:0007548;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011618.1|UniProtKB=W5N0X7 W5N0X7 PTHR16705:SF9 COMPLEXIN COMPLEXIN-2 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;export from cell#GO:0140352;regulation of signaling#GO:0023051;cellular localization#GO:0051641;secretion by cell#GO:0032940;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;neurotransmitter transport#GO:0006836;regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;regulation of transport#GO:0051049;regulation of localization#GO:0032879 membrane#GO:0016020;presynapse#GO:0098793;neuron projection#GO:0043005;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cell junction#GO:0030054;axon terminus#GO:0043679;membrane protein complex#GO:0098796;synapse#GO:0045202;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;neuron projection terminus#GO:0044306;cell projection#GO:0042995;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;axon#GO:0030424;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006156.1|UniProtKB=W5MGF7 W5MGF7 PTHR24023:SF1124 COLLAGEN ALPHA COLLAGEN, TYPE I, ALPHA 1B PRECURSOR structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;animal organ morphogenesis#GO:0009887;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;external encapsulating structure organization#GO:0045229;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;skeletal system morphogenesis#GO:0048705;skin development#GO:0043588;multicellular organismal process#GO:0032501;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000010939.1|UniProtKB=W5MYF4 W5MYF4 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 LEPOC|Ensembl=ENSLOCG00000009676.1|UniProtKB=W5MTW2 W5MTW2 PTHR47266:SF40 ENDONUCLEASE-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007017.1|UniProtKB=W5MJD6 W5MJD6 PTHR11758:SF16 40S RIBOSOMAL PROTEIN S15A SMALL RIBOSOMAL SUBUNIT PROTEIN US8 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004963.1|UniProtKB=W5MC68 W5MC68 PTHR23319:SF8 GRAM DOMAIN CONTAINING 1B, ISOFORM E PROTEIN ASTER-A molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;cholesterol binding#GO:0015485;lipid transfer activity#GO:0120013;transporter activity#GO:0005215;sterol transfer activity#GO:0120015;steroid binding#GO:0005496;alcohol binding#GO:0043178;cholesterol transfer activity#GO:0120020 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular sterol transport#GO:0032366;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;intracellular transport#GO:0046907;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;sterol transport#GO:0015918;establishment of localization#GO:0051234;cellular localization#GO:0051641 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane contact site#GO:0044232;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000013895.1|UniProtKB=W5N929 W5N929 PTHR24200:SF16 TOUCAN, ISOFORM A MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR 1 HOMOLOG A tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000003769.1|UniProtKB=W5M7Y5 W5M7Y5 PTHR14958:SF12 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD5 binding#GO:0005488;protein binding#GO:0005515 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007654.1|UniProtKB=W5MLP7 W5MLP7 PTHR11590:SF73 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009634.1|UniProtKB=W5MTR5 W5MTR5 PTHR44899:SF4 CAMK FAMILY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE NEK1 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011969.1|UniProtKB=W5N258 W5N258 PTHR12429:SF13 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 import into cell#GO:0098657;positive regulation of cell differentiation#GO:0045597;regulation of trans-synaptic signaling#GO:0099177;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;protein transport#GO:0015031;regulation of biological quality#GO:0065008;regulation of signaling#GO:0023051;positive regulation of nervous system development#GO:0051962;endocytosis#GO:0006897;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of neuronal synaptic plasticity#GO:0048168;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;regulation of synaptic plasticity#GO:0048167;positive regulation of developmental process#GO:0051094;regulation of response to stimulus#GO:0048583;transport#GO:0006810;regulation of cell differentiation#GO:0045595;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;macromolecule localization#GO:0033036;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;localization#GO:0051179;regulation of nervous system development#GO:0051960;regulation of Notch signaling pathway#GO:0008593;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;modulation of chemical synaptic transmission#GO:0050804;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;positive regulation of neurogenesis#GO:0050769;regulation of neurogenesis#GO:0050767 cell junction#GO:0030054;postsynaptic density#GO:0014069;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;organelle#GO:0043226;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;plasma membrane#GO:0005886;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 LEPOC|Ensembl=ENSLOCG00000009593.1|UniProtKB=W5MTL1 W5MTL1 PTHR23302:SF18 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 response to external stimulus#GO:0009605;system process#GO:0003008;detection of mechanical stimulus#GO:0050982;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;response to mechanical stimulus#GO:0009612 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000004855.1|UniProtKB=W5MBR8 W5MBR8 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;glycoprotein biosynthetic process#GO:0009101;aminoglycan biosynthetic process#GO:0006023;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007993.1|UniProtKB=W5MMV7 W5MMV7 PTHR13351:SF1 RENIN RECEPTOR RENIN RECEPTOR positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signal transduction#GO:0009967 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011079.1|UniProtKB=W5MZ02 W5MZ02 PTHR11705:SF19 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE O metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000014115.1|UniProtKB=W5N9T1 W5N9T1 PTHR22802:SF470 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014488.1|UniProtKB=W5NB27 W5NB27 PTHR15108:SF0 N-ACYLGLUCOSAMINE-2-EPIMERASE N-ACYLGLUCOSAMINE 2-EPIMERASE isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824 epimerase/racemase#PC00096 LEPOC|Ensembl=ENSLOCG00000008610.1|UniProtKB=W5MQ09 W5MQ09 PTHR12294:SF1 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873 mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;transporter complex#GO:1990351;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000008331.1|UniProtKB=W5MP09 W5MP09 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002164.1|UniProtKB=W5M2B6 W5M2B6 PTHR11534:SF2 MYOGENIC FACTOR MYOBLAST DETERMINATION PROTEIN 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;animal organ development#GO:0048513;striated muscle tissue development#GO:0014706;positive regulation of cell differentiation#GO:0045597;muscle organ development#GO:0007517;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;muscle tissue development#GO:0060537;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;skeletal muscle tissue development#GO:0007519;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009472.1|UniProtKB=W5MT57 W5MT57 PTHR15335:SF7 PROTEIN TFG PROTEIN TFG cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015863.1|UniProtKB=W5NFX1 W5NFX1 PTHR13037:SF23 FORMIN ACTIN NUCLEATION-PROMOTING FACTOR WASL protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;microtubule binding#GO:0008017 actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;membraneless organelle#GO:0043228;organelle membrane#GO:0031090 Huntington disease#P00029>N-Wasp#P00769;Cytoskeletal regulation by Rho GTPase#P00016>N-WASP#P00525 LEPOC|Ensembl=ENSLOCG00000003594.1|UniProtKB=W5M7A1 W5M7A1 PTHR11214:SF153 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;oligosaccharide biosynthetic process#GO:0009312;oligosaccharide metabolic process#GO:0009311 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000012378.1|UniProtKB=W5N3N0 W5N3N0 PTHR15642:SF3 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009006.1|UniProtKB=W5MRG8 W5MRG8 PTHR24083:SF47 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP F MEMBER 6 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000017005.1|UniProtKB=W5NK59 W5NK59 KATNA1 PTHR23074:SF71 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A1 ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000016854.1|UniProtKB=W5NJM9 W5NJM9 PTHR45656:SF22 PROTEIN CBR-CLEC-78 CUB AND SUSHI MULTIPLE DOMAINS 1 LEPOC|Ensembl=ENSLOCG00000003475.1|UniProtKB=W5M6W3 W5M6W3 PTHR11567:SF215 ACID PHOSPHATASE-RELATED LYSOSOMAL ACID PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;acid phosphatase activity#GO:0003993 lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000017498.1|UniProtKB=W5NLU4 W5NLU4 PTHR45773:SF3 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 4 positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;positive regulation of synapse assembly#GO:0051965;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;regulation of cell junction assembly#GO:1901888;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;regulation of synapse organization#GO:0050807;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell morphogenesis#GO:0000902 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000754.1|UniProtKB=W5LXH7 W5LXH7 PTHR23411:SF41 TAPASIN IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006969.1|UniProtKB=W5MJ73 W5MJ73 PTHR12652:SF7 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11B cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;organelle organization#GO:0006996;cellular component organization#GO:0016043;peroxisome organization#GO:0007031;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000008941.1|UniProtKB=W5MR92 W5MR92 PTHR43243:SF28 INNER MEMBRANE TRANSPORTER YGJI-RELATED HIGH AFFINITY CATIONIC AMINO ACID TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 establishment of localization#GO:0051234;localization#GO:0051179;amino acid transport#GO:0006865;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 amino acid transporter#PC00046;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000016257.1|UniProtKB=W5NHE0 W5NHE0 PTHR24346:SF56 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE MARK2 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012676.1|UniProtKB=W5N4P0 W5N4P0 PTHR11441:SF0 THYMIDINE KINASE THYMIDINE KINASE, CYTOSOLIC transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;deoxynucleoside kinase activity#GO:0019136 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleoside monophosphate biosynthetic process#GO:0009124;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 kinase#PC00137;nucleotide kinase#PC00172 Salvage pyrimidine deoxyribonucleotides#P02774>Deoxyuridine kinase#P03146;Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine kinase#P03147 LEPOC|Ensembl=ENSLOCG00000017925.1|UniProtKB=W5NN19 W5NN19 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003430.1|UniProtKB=W5M6S1 W5M6S1 PTHR14453:SF89 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14 transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;transferase activity#GO:0016740;transcription coregulator activity#GO:0003712;glycosyltransferase activity#GO:0016757;transcription regulator activity#GO:0140110;pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;negative regulation of immune response#GO:0050777;regulation of immune system process#GO:0002682;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;negative regulation of response to cytokine stimulus#GO:0060761;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cytokine-mediated signaling pathway#GO:0001959;negative regulation of cytokine-mediated signaling pathway#GO:0001960;regulation of response to external stimulus#GO:0032101;negative regulation of signal transduction#GO:0009968;negative regulation of innate immune response#GO:0045824;negative regulation of response to external stimulus#GO:0032102;regulation of response to cytokine stimulus#GO:0060759;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010574.1|UniProtKB=W5MX53 W5MX53 PTHR47157:SF1 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1-LIKE ATP-DEPENDENT CHROMATIN REMODELER CHD1L heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular component organization#GO:0016043;response to stress#GO:0006950;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000005212.1|UniProtKB=W5MD15 W5MD15 PTHR24394:SF36 ZINC FINGER PROTEIN BCL6A TRANSCRIPTION REPRESSOR A ISOFORM X1 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013868.1|UniProtKB=W5N8Z7 W5N8Z7 PTHR12928:SF0 FRG1 PROTEIN PROTEIN FRG1 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000012492.1|UniProtKB=W5N427 W5N427 PTHR11629:SF113 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE SUBUNIT A active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;enzyme binding#GO:0019899;binding#GO:0005488 cellular component disassembly#GO:0022411;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;process utilizing autophagic mechanism#GO:0061919;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;autophagy#GO:0006914;monoatomic cation transmembrane transport#GO:0098655;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;monoatomic cation transport#GO:0006812;localization#GO:0051179;catabolic process#GO:0009056;homeostatic process#GO:0042592;protein-containing complex disassembly#GO:0032984;autophagosome maturation#GO:0097352;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion transmembrane transport#GO:0034220;macroautophagy#GO:0016236;biological regulation#GO:0065007 proton-transporting two-sector ATPase complex#GO:0016469;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000012899.1|UniProtKB=W5N5G6 W5N5G6 PTHR14167:SF45 SH3 DOMAIN-CONTAINING ENDOPHILIN-A3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytosol#GO:0005829;presynapse#GO:0098793;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Huntington disease#P00029>SH3GL3#P00813 LEPOC|Ensembl=ENSLOCG00000002670.1|UniProtKB=W5M427 W5M427 PTHR12050:SF4 LEPTIN RECEPTOR-RELATED LEPTIN RECEPTOR OVERLAPPING TRANSCRIPT-LIKE 1 endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016533.1|UniProtKB=W5NIG0 W5NIG0 PTHR23138:SF141 RAN BINDING PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP50 nucleocytoplasmic transport#GO:0006913;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015519.1|UniProtKB=W5NEN8 W5NEN8 PTHR45712:SF11 AGAP008170-PA BIGLYCAN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014052.1|UniProtKB=W5N9L2 W5N9L2 PTHR17130:SF14 MITOCHONDRIAL OUTER MEMBRANE PROTEIN 25 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX16 HOMOLOG, MITOCHONDRIAL cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000005588.1|UniProtKB=W5MED6 W5MED6 PTHR28617:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004344.1|UniProtKB=W5M9Y2 W5M9Y2 PTHR21354:SF0 ZINC FINGER PROTEIN 511 ZINC FINGER PROTEIN 511 LEPOC|Ensembl=ENSLOCG00000001617.1|UniProtKB=W5M0F4 W5M0F4 PTHR33960:SF1 SIMILAR TO KIAA0825 PROTEIN KIAA0825 HOMOLOG LEPOC|Ensembl=ENSLOCG00000009596.1|UniProtKB=W5MTL2 W5MTL2 PTHR31785:SF2 UPF0524 PROTEIN C3ORF70 UPF0524 PROTEIN C3ORF70 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;system development#GO:0048731;circadian rhythm#GO:0007623;animal gross anatomical part developmental process#GO:0160108;rhythmic process#GO:0048511;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 LEPOC|Ensembl=ENSLOCG00000001091.1|UniProtKB=W5LYM4 W5LYM4 PTHR21462:SF2 CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR CD200 RECEPTOR 1A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;side of membrane#GO:0098552 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014366.1|UniProtKB=W5NAN0 W5NAN0 PTHR24377:SF1028 IP01015P-RELATED ZINC FINGER PROTEIN 84 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000006355.1|UniProtKB=W5MH20 W5MH20 PTHR23220:SF26 INTEGRIN ALPHA INTEGRIN ALPHA-10 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;signaling receptor complex#GO:0043235;integrin complex#GO:0008305 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000010729.1|UniProtKB=W5MXN7 W5MXN7 PTHR24345:SF89 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK4 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cytoskeleton organization#GO:0007010;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;membraneless organelle#GO:0043228;chromosome#GO:0005694;spindle pole#GO:0000922;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002614.1|UniProtKB=W5M3X1 W5M3X1 PTHR24027:SF311 CADHERIN-23 CADHERIN-22 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell junction organization#GO:0034330;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cell migration#GO:0016477;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000018012.1|UniProtKB=W5NNA4 W5NNA4 PTHR11984:SF26 CONNEXIN GAP JUNCTION BETA-7 PROTEIN passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;anchoring junction#GO:0070161;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000017307.1|UniProtKB=W5NLA3 W5NLA3 PTHR11437:SF67 RIBONUCLEASE RNASE 2-RELATED nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 response to stimulus#GO:0050896;circulatory system development#GO:0072359;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to Gram-negative bacterium#GO:0050829;blood vessel morphogenesis#GO:0048514;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;defense response to Gram-positive bacterium#GO:0050830;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;multicellular organismal process#GO:0032501;response to other organism#GO:0051707;tube development#GO:0035295;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;multicellular organism development#GO:0007275;vasculature development#GO:0001944;defense response#GO:0006952;anatomical structure formation involved in morphogenesis#GO:0048646;response to external stimulus#GO:0009605;developmental process#GO:0032502 RNA metabolism protein#PC00031;endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000005533.1|UniProtKB=W5ME71 W5ME71 PTHR12127:SF24 MUCOLIPIN MUCOLIPIN-2 monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ligand-gated monoatomic cation channel activity#GO:0099094;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836 membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001444.1|UniProtKB=W5LZU2 W5LZU2 PTHR28642:SF1 MEIOSIS 1 ARREST PROTEIN MEIOSIS 1 ARREST PROTEIN male meiotic nuclear division#GO:0007140;male gamete generation#GO:0048232;cellular process#GO:0009987;organelle organization#GO:0006996;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;chromosome separation#GO:0051304;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;spermatogenesis#GO:0007283;developmental process#GO:0032502;meiotic cell cycle#GO:0051321;reproductive process#GO:0022414;gamete generation#GO:0007276;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;multicellular organismal reproductive process#GO:0048609;organelle fission#GO:0048285;sexual reproduction#GO:0019953;nuclear division#GO:0000280 LEPOC|Ensembl=ENSLOCG00000011068.1|UniProtKB=W5MYY3 W5MYY3 PTHR10351:SF75 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000003832.1|UniProtKB=W5M875 W5M875 PTHR24253:SF86 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 3 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 proteolysis#GO:0006508;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;sensory perception of sound#GO:0007605;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;system process#GO:0003008;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002440.1|UniProtKB=W5M3B0 W5M3B0 PTHR24330:SF7 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN BARH-LIKE 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011390.1|UniProtKB=W5N043 W5N043 PTHR45011:SF1 DAP3-BINDING CELL DEATH ENHANCER 1 DAP3-BINDING CELL DEATH ENHANCER 1 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 cellular response to stress#GO:0033554;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000009200.1|UniProtKB=W5MS69 W5MS69 PTHR45734:SF3 TENSIN TENSIN-1 cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000008369.1|UniProtKB=W5MP66 W5MP66 PTHR43107:SF16 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN-FATTY-ACID--COA LIGASE ATP-dependent activity#GO:0140657;carboxylic acid transmembrane transporter activity#GO:0046943;ligase activity, forming carbon-sulfur bonds#GO:0016877;monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;transporter activity#GO:0005215;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;long-chain fatty acid metabolic process#GO:0001676;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid metabolic process#GO:0006629;establishment of localization#GO:0051234;import into cell#GO:0098657 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000013415.1|UniProtKB=W5N7D2 W5N7D2 PTHR14057:SF9 TRANSCRIPTION FACTOR ONECUT HEPATOCYTE NUCLEAR FACTOR 6 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008927.1|UniProtKB=W5MR64 W5MR64 PTHR12918:SF1 CYSTEINE DIOXYGENASE CYSTEINE DIOXYGENASE TYPE 1 ferrous iron binding#GO:0008198;catalytic activity#GO:0003824;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;cation binding#GO:0043169 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;sulfur compound catabolic process#GO:0044273;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000001131.1|UniProtKB=W5LYS2 W5LYS2 PTHR19143:SF444 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-3 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000009632.1|UniProtKB=W5MTR2 W5MTR2 PTHR11071:SF257 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NK-TUMOR RECOGNITION PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002841.1|UniProtKB=W5M4M9 W5M4M9 PTHR10498:SF24 PARALEMMIN-RELATED PALM2 AND AKAP2 FUSION LEPOC|Ensembl=ENSLOCG00000012930.1|UniProtKB=W5N5M1 W5N5M1 PTHR10589:SF19 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>UCH-L1#P01210 LEPOC|Ensembl=ENSLOCG00000008317.1|UniProtKB=W5MP00 W5MP00 PTHR24103:SF667 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM69 ISOFORM X1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016906.1|UniProtKB=W5NJU8 W5NJU8 PTHR13140:SF745 MYOSIN UNCONVENTIONAL MYOSIN-VI isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146 actin filament-based movement#GO:0030048;inner ear development#GO:0048839;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;developmental process#GO:0032502;sensory organ development#GO:0007423;epidermis development#GO:0008544;actin filament organization#GO:0007015;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;actin cytoskeleton organization#GO:0030036;animal organ morphogenesis#GO:0009887;embryonic organ development#GO:0048568;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;inner ear morphogenesis#GO:0042472;hair cell differentiation#GO:0035315;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;embryo development#GO:0009790;neuron differentiation#GO:0030182;embryonic morphogenesis#GO:0048598;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell differentiation#GO:0030154;sensory organ morphogenesis#GO:0090596;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;ear development#GO:0043583 intracellular vesicle#GO:0097708;actin cytoskeleton#GO:0015629;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;ruffle#GO:0001726 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000003032.1|UniProtKB=W5M5B1 W5M5B1 PTHR31815:SF2 AGAP005329-PA TRANSMEMBRANE PROTEIN 200C LEPOC|Ensembl=ENSLOCG00000015546.1|UniProtKB=W5NET3 W5NET3 PTHR10292:SF11 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN LINKER DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;clathrin binding#GO:0030276;protein binding#GO:0005515 localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005323.1|UniProtKB=W5MDF0 W5MDF0 PTHR45918:SF1 ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2 ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000008074.1|UniProtKB=W5MN48 W5MN48 PTHR12755:SF6 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000002808.1|UniProtKB=W5M4J5 W5M4J5 PTHR12265:SF30 TRANSMEMBRANE PROTEIN 53 TRANSMEMBRANE PROTEIN 53 LEPOC|Ensembl=ENSLOCG00000014903.1|UniProtKB=W5NCJ2 W5NCJ2 PTHR16236:SF0 TRANSMEMBRANE PROTEIN 160 TRANSMEMBRANE PROTEIN 160 LEPOC|Ensembl=ENSLOCG00000016595.1|UniProtKB=W5NIN7 W5NIN7 PTHR12247:SF85 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010168.1|UniProtKB=W5MVP4 W5MVP4 PTHR19370:SF74 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE 1 ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000004973.1|UniProtKB=W5MC77 W5MC77 PTHR19212:SF5 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000018301.1|UniProtKB=W5NP43 W5NP43 PTHR11214:SF361 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000008483.1|UniProtKB=W5MPM3 W5MPM3 PTHR11731:SF202 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE FAMILY MEMBER 2 peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000014249.1|UniProtKB=W5NA84 W5NA84 PTHR46923:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2 developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;sperm motility#GO:0097722;anatomical structure maturation#GO:0071695;gamete generation#GO:0007276;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;fertilization#GO:0009566;cell development#GO:0048468;spermatid differentiation#GO:0048515;spermatid development#GO:0007286;cilium movement#GO:0003341;sexual reproduction#GO:0019953;cilium or flagellum-dependent cell motility#GO:0001539;anatomical structure development#GO:0048856;cilium-dependent cell motility#GO:0060285;multicellular organismal reproductive process#GO:0048609;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;male gamete generation#GO:0048232;developmental maturation#GO:0021700;sperm capacitation#GO:0048240;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;cell maturation#GO:0048469;microtubule-based process#GO:0007017 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001861.1|UniProtKB=W5M1B6 W5M1B6 PTHR47678:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 31 TETRATRICOPEPTIDE REPEAT PROTEIN 31 LEPOC|Ensembl=ENSLOCG00000013695.1|UniProtKB=W5N8C6 W5N8C6 PTHR23249:SF16 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 1 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013336.1|UniProtKB=W5N729 W5N729 PTHR11675:SF3 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 16 catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000017138.1|UniProtKB=W5NKM5 W5NKM5 PTHR24416:SF527 TYROSINE-PROTEIN KINASE RECEPTOR PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713 cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007146.1|UniProtKB=W5MJU2 W5MJU2 PTHR46440:SF1 HOMEOBOX PROTEIN HOX-D12-RELATED HOMEOBOX PROTEIN HOX-D12 DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000017829.1|UniProtKB=W5NMS3 W5NMS3 PTHR19290:SF88 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;sensory organ development#GO:0007423;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000010476.1|UniProtKB=W5MWT6 W5MWT6 PTHR14592:SF11 UNCHARACTERIZED FAM3 PROTEIN FAM3A cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005542.1|UniProtKB=W5ME81 W5ME81 PTHR12035:SF125 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 5 organic acid binding#GO:0043177;binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;carbohydrate derivative binding#GO:0097367 cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000002008.1|UniProtKB=W5M1S8 W5M1S8 PTHR44188:SF2 GDAP1, ISOFORM A GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 1-LIKE 1 organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;mitochondrial fission#GO:0000266;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular process#GO:0009987 membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000016853.1|UniProtKB=W5NJM4 W5NJM4 PTHR45740:SF4 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP11 pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003316.1|UniProtKB=W5M6A9 W5M6A9 PTHR47034:SF1 ZINC FINGER TRANSCRIPTION FACTOR TRPS1 ZINC FINGER TRANSCRIPTION FACTOR TRPS1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016905.1|UniProtKB=W5NJU3 W5NJU3 PTHR24241:SF75 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OREXIN RECEPTOR TYPE 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015591.1|UniProtKB=W5NEY7 W5NEY7 PTHR12745:SF12 SUPPRESSION OF TUMORIGENICITY 7 SUPPRESSOR OF TUMORIGENICITY 7 PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000013872.1|UniProtKB=W5N900 W5N900 PTHR24393:SF190 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 13 transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008681.1|UniProtKB=W5MQC5 W5MQC5 PTHR14226:SF26 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 6 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298;hydrolase activity#GO:0016787 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000009228.1|UniProtKB=W5MS98 W5MS98 PTHR43899:SF48 RH59310P 3-KETOACYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017332.1|UniProtKB=W5NLC8 W5NLC8 PTHR22791:SF3 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF182-RELATED acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014026.1|UniProtKB=W5N9I3 W5N9I3 PTHR10663:SF327 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 1 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;biological regulation#GO:0065007;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100 plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000004794.1|UniProtKB=W5MBJ0 W5MBJ0 PTHR24347:SF427 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK3 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016917.1|UniProtKB=W5NJV5 W5NJV5 PTHR22775:SF44 SORTING NEXIN SORTING NEXIN-14 ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;small molecule binding#GO:0036094 metabolic process#GO:0008152;autophagosome maturation#GO:0097352;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;autophagy#GO:0006914;cellular process#GO:0009987;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;macroautophagy#GO:0016236 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000870.1|UniProtKB=W5LXW1 W5LXW1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017772.1|UniProtKB=W5NML7 W5NML7 PTHR24232:SF82 G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 8-LIKE ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007994.1|UniProtKB=W5MMW8 W5MMW8 PTHR13707:SF23 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000005821.1|UniProtKB=W5MF70 W5MF70 PTHR12489:SF19 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 2 PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004124.1|UniProtKB=W5M970 W5M970 PTHR24056:SF243 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 8 cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;transferase complex#GO:1990234;mediator complex#GO:0016592;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005195.1|UniProtKB=W5MD19 W5MD19 PTHR24027:SF89 CADHERIN-23 CADHERIN-5 protein phosphatase binding#GO:0019903;beta-catenin binding#GO:0008013;protein binding#GO:0005515;enzyme binding#GO:0019899;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;phosphatase binding#GO:0019902 cell motility#GO:0048870;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043 tight junction#GO:0070160;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;adherens junction#GO:0005912;apical junction complex#GO:0043296;protein-containing complex#GO:0032991;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000001998.1|UniProtKB=W5M1P8 W5M1P8 PTHR23244:SF467 KELCH REPEAT DOMAIN EF-HAND DOMAIN-CONTAINING PROTEIN cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000004272.1|UniProtKB=W5M9W3 W5M9W3 PTHR22829:SF1 DEP DOMAIN PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 2 PROTEIN kinase inhibitor activity#GO:0019210;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function activator activity#GO:0140677;guanyl-nucleotide exchange factor activity#GO:0005085 cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001451.1|UniProtKB=W5LZU6 W5LZU6 PTHR45640:SF5 HEAT SHOCK PROTEIN HSP-12.2-RELATED ALPHA-CRYSTALLIN B CHAIN negative regulation of apoptotic process#GO:0043066;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;biological regulation#GO:0065007;response to heat#GO:0009408;response to stress#GO:0006950;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;protein folding#GO:0006457;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;protein refolding#GO:0042026 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 LEPOC|Ensembl=ENSLOCG00000009413.1|UniProtKB=W5MSY2 W5MSY2 PTHR18945:SF883 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A ISOFORM X1 monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;transport#GO:0006810;establishment of localization#GO:0051234;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000007681.1|UniProtKB=W5MLR5 W5MLR5 PTHR31302:SF0 TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN-RELATED TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN LEPOC|Ensembl=ENSLOCG00000007764.1|UniProtKB=W5MM21 W5MM21 PTHR10517:SF14 FOLATE RECEPTOR FOLATE RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;cargo receptor activity#GO:0038024;molecular transducer activity#GO:0060089 nitrogen compound transport#GO:0071705;dicarboxylic acid transport#GO:0006835;vitamin transport#GO:0051180;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;localization#GO:0051179;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000013659.1|UniProtKB=W5N881 W5N881 PTHR22883:SF270 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC15 catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;developmental process#GO:0032502;protein targeting to membrane#GO:0006612;developmental maturation#GO:0021700;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting#GO:0006605;cellular component organization#GO:0016043 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009247.1|UniProtKB=W5MSD3 W5MSD3 PTHR13976:SF36 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000006322.1|UniProtKB=W5MGX2 W5MGX2 PTHR21446:SF12 DUF3504 DOMAIN-CONTAINING PROTEIN POTASSIUM CHANNEL TETRAMERIZATION DOMAIN CONTAINING 1 LEPOC|Ensembl=ENSLOCG00000013633.1|UniProtKB=W5N847 W5N847 PTHR12107:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-4 SUBUNIT monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;transmission of nerve impulse#GO:0019226;system process#GO:0003008;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051;nervous system process#GO:0050877;localization within membrane#GO:0051668;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;localization#GO:0051179;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cell junction#GO:0030054;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495 ion channel#PC00133;transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000006536.1|UniProtKB=W5MHN8 W5MHN8 PTHR12306:SF16 CELL DEATH ACTIVATOR CIDE DNAATION FACTOR SUBUNIT ALPHA lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 regulation of catabolic process#GO:0009894;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;organelle fusion#GO:0048284;negative regulation of apoptotic process#GO:0043066;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;lipid storage#GO:0019915;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of catabolic process#GO:0009895;lipid droplet organization#GO:0034389;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA metabolic process#GO:0051052;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785 LEPOC|Ensembl=ENSLOCG00000009484.1|UniProtKB=W5MT73 W5MT73 PTHR15967:SF1 E2F-ASSOCIATED PHOSPHOPROTEIN E2F-ASSOCIATED PHOSPHOPROTEIN transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000006882.1|UniProtKB=W5MIW7 W5MIW7 PTHR19304:SF10 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-7 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302 LEPOC|Ensembl=ENSLOCG00000009347.1|UniProtKB=W5MSP4 W5MSP4 PTHR21462:SF2 CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR CD200 RECEPTOR 1A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005922.1|UniProtKB=W5MFJ6 W5MFJ6 PTHR12646:SF0 NOT56 - RELATED DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000018334.1|UniProtKB=W5NP76 W5NP76 PTHR24232:SF7 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 20 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013606.1|UniProtKB=W5N816 W5N816 PTHR11188:SF183 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001991.1|UniProtKB=W5M1P9 W5M1P9 PTHR24240:SF152 OPSIN OPSIN, PINEAL-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;signal transduction#GO:0007165;detection of stimulus#GO:0051606;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to radiation#GO:0071478;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to light stimulus#GO:0009416 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011497.1|UniProtKB=W5N0H0 W5N0H0 PTHR22793:SF6 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN-RELATED TRANSCRIPTION FACTOR A cell differentiation#GO:0030154;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000002600.1|UniProtKB=W5M3V1 W5M3V1 PTHR13045:SF14 5'-NUCLEOTIDASE CYTOSOLIC 5'-NUCLEOTIDASE 3A phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 esterase#PC00097;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009243.1|UniProtKB=W5MSB2 W5MSB2 PTHR11009:SF1 DER1-LIKE PROTEIN, DERLIN DERLIN-1 intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;response to unfolded protein#GO:0006986;cellular response to topologically incorrect protein#GO:0035967;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017866.1|UniProtKB=W5NMW0 W5NMW0 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017405.1|UniProtKB=W5NLK1 W5NLK1 PTHR22911:SF144 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G2A-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008071.1|UniProtKB=W5MN41 W5MN41 PTHR15243:SF0 SERINE/THREONINE-PROTEIN KINASE 19 WINGED HELIX REPAIR FACTOR 1 DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of response to stress#GO:0080134;regulation of cellular response to stress#GO:0080135 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000014748.1|UniProtKB=W5NC03 W5NC03 PTHR45783:SF1 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 3 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 LEPOC|Ensembl=ENSLOCG00000012806.1|UniProtKB=W5N556 W5N556 PTHR15535:SF24 TRANSMEMBRANE PROTEIN 2-RELATED HYALURONOGLUCOSAMINIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;glycosaminoglycan catabolic process#GO:0006027 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000007063.1|UniProtKB=W5MJP0 W5MJP0 PTHR13140:SF255 MYOSIN UNCONVENTIONAL MYOSIN-IC catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 actin filament-based movement#GO:0030048;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;transport#GO:0006810;actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000015856.1|UniProtKB=W5NFW2 W5NFW2 PTHR46216:SF3 PROSAPOSIN RECEPTOR GPR37 FAMILY MEMBER PROSAPOSIN RECEPTOR GPR37 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154;positive regulation of signaling#GO:0023056 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Parkinson disease#P00049>Pael-R#P01229 LEPOC|Ensembl=ENSLOCG00000000646.1|UniProtKB=W5LX58 W5LX58 PTHR11505:SF204 L1 TRANSPOSABLE ELEMENT-RELATED L1 TRANSPOSABLE ELEMENT RRM DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000003077.1|UniProtKB=W5M5G4 W5M5G4 PTHR19818:SF27 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000017433.1|UniProtKB=W5NLM9 W5NLM9 PTHR12002:SF192 CLAUDIN CLAUDIN cellular process#GO:0009987;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;paracellular transport#GO:0160184 apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000016843.1|UniProtKB=W5NJL1 W5NJL1 PTHR19282:SF198 TETRASPANIN TETRASPANIN-11 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000601.1|UniProtKB=W5LX04 W5LX04 PTHR15196:SF0 CILIARY NEUROTROPHIC FACTOR CILIARY NEUROTROPHIC FACTOR cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 defense response#GO:0006952;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;positive regulation of cell projection organization#GO:0031346;cell activation#GO:0001775;inflammatory response#GO:0006954;cytokine-mediated signaling pathway#GO:0019221;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;gliogenesis#GO:0042063;positive regulation of response to external stimulus#GO:0032103;multicellular organism development#GO:0007275;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;cell surface receptor signaling pathway via STAT#GO:0097696;regulation of response to external stimulus#GO:0032101;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;response to stress#GO:0006950;negative regulation of neuron apoptotic process#GO:0043524;regulation of neuron apoptotic process#GO:0043523;regulation of response to wounding#GO:1903034;response to peptide#GO:1901652;regulation of cellular response to stress#GO:0080135;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;positive regulation of neuron projection development#GO:0010976;cell development#GO:0048468;signaling#GO:0023052;cell differentiation#GO:0030154;central nervous system development#GO:0007417;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell body#GO:0044297;axon#GO:0030424 LEPOC|Ensembl=ENSLOCG00000012871.1|UniProtKB=W5N5D3 W5N5D3 PTHR31516:SF22 STABILIZER OF AXONEMAL MICROTUBULES 2 STABILIZER OF AXONEMAL MICROTUBULES 2 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 motile cilium#GO:0031514;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasmic microtubule#GO:0005881;microtubule#GO:0005874;axoneme#GO:0005930;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000013235.1|UniProtKB=W5N6P7 W5N6P7 PTHR18921:SF2 MYOSIN HEAVY CHAIN - RELATED THYROID RECEPTOR-INTERACTING PROTEIN 11 protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488;enzyme binding#GO:0019899 endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 actin or actin-binding cytoskeletal protein#PC00041;actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000003990.1|UniProtKB=W5M8Q3 W5M8Q3 PTHR16024:SF13 XK-RELATED PROTEIN XK-RELATED PROTEIN 9 lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cellular component organization#GO:0016043;endocytosis#GO:0006897;membrane invagination#GO:0010324;apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;cellular process#GO:0009987;endomembrane system organization#GO:0010256;localization#GO:0051179;anatomical structure development#GO:0048856;cell death#GO:0008219;programmed cell death#GO:0012501;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;developmental process#GO:0032502;transport#GO:0006810;phagocytosis#GO:0006909;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000002027.1|UniProtKB=W5M1U5 W5M1U5 PTHR23085:SF26 GH28348P JUNCTOPHILIN-2 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;sarcoplasmic reticulum#GO:0016529;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000007052.1|UniProtKB=W5MJH5 W5MJH5 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organelle organization#GO:0006996;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;telomere organization#GO:0032200;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000011407.1|UniProtKB=W5N063 W5N063 PTHR24028:SF42 CADHERIN-87A PROTOCADHERIN-12 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000002723.1|UniProtKB=W5M4A6 W5M4A6 PTHR24123:SF65 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 50 vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000723.1|UniProtKB=W5LXE2 W5LXE2 PTHR28661:SF3 SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 1 MICROTUBULE NUCLEATION FACTOR SSNA1 multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;developmental growth#GO:0048589;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;developmental cell growth#GO:0048588;anatomical structure development#GO:0048856;system development#GO:0048731;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;axon extension#GO:0048675;neuron projection development#GO:0031175;cellular process#GO:0009987;cell growth#GO:0016049;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;neuron projection extension#GO:1990138;neuron development#GO:0048666;developmental growth involved in morphogenesis#GO:0060560;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centrosome#GO:0005813;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;axon#GO:0030424;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014128.1|UniProtKB=W5N9U7 W5N9U7 PTHR42782:SF2 SI:CH73-314G15.3 SI:CH73-314G15.3 LEPOC|Ensembl=ENSLOCG00000011609.1|UniProtKB=W5N0V7 W5N0V7 PTHR13064:SF1 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER PROTON-TRANSPORTING V-TYPE ATPASE COMPLEX ASSEMBLY REGULATOR TMEM9 LEPOC|Ensembl=ENSLOCG00000000812.1|UniProtKB=W5LXP8 W5LXP8 PTHR23421:SF172 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 hydrolase#PC00121;galactosidase#PC00104 LEPOC|Ensembl=ENSLOCG00000015009.1|UniProtKB=W5NCW8 W5NCW8 PTHR12566:SF9 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;translation factor activity#GO:0180051;translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of translation#GO:0017148;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection#GO:0043005;nucleus#GO:0005634 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000015274.1|UniProtKB=W5NDT6 W5NDT6 PTHR23430:SF280 HISTONE H2A HISTONE H2A.V structural molecule activity#GO:0005198 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001449.1|UniProtKB=W5LZV8 W5LZV8 PTHR13237:SF8 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED SOMETHING ABOUT SILENCING PROTEIN 10 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005228.1|UniProtKB=W5MD35 W5MD35 PTHR13829:SF2 SNRNP CORE PROTEIN FAMILY MEMBER U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2 binding#GO:0005488;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U6 snRNP#GO:0005688;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000016850.1|UniProtKB=W5NJM2 W5NJM2 PTHR11727:SF17 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;transcription regulator activity#GO:0140110;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102 methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;DNA-templated transcription initiation#GO:0006352;rRNA modification#GO:0000154;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;mitochondrial gene expression#GO:0140053;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;mitochondrial RNA metabolic process#GO:0000959;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;mitochondrial transcription#GO:0006390;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016443.1|UniProtKB=W5NI50 W5NI50 PTHR11848:SF300 TGF-BETA FAMILY CVG1 PROTEIN cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000007082.1|UniProtKB=W5MJL4 W5MJL4 PTHR11639:SF130 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A11 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515 extracellular region#GO:0005576;perinuclear region of cytoplasm#GO:0048471;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000001181.1|UniProtKB=W5LYX5 W5LYX5 PTHR42886:SF34 RE40534P-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5 hydrolase activity#GO:0016787;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 organophosphate biosynthetic process#GO:0090407;positive regulation of metabolic process#GO:0009893;regulation of lipid metabolic process#GO:0019216;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;regulation of lipid catabolic process#GO:0050994;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016192.1|UniProtKB=W5NH50 W5NH50 PTHR47573:SF1 PROTEIN AF-9 HOMOLOG PROTEIN AF-9 HOMOLOG LEPOC|Ensembl=ENSLOCG00000015159.1|UniProtKB=W5NDF1 W5NDF1 PTHR24278:SF41 COAGULATION FACTOR COAGULATION FACTOR IX serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000008699.1|UniProtKB=W5MQC0 W5MQC0 PTHR11046:SF15 OLIGORIBONUCLEASE, MITOCHONDRIAL SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 2 ISOFORM X1 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011405.1|UniProtKB=W5N067 W5N067 PTHR24012:SF733 RNA BINDING PROTEIN TIA1 CYTOTOXIC GRANULE-ASSOCIATED RNA BINDING PROTEIN-LIKE 1 mRNA 3'-UTR binding#GO:0003730;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608 cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011508.1|UniProtKB=W5N0J6 W5N0J6 PTHR19229:SF34 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA1 lipid carrier activity#GO:0005319;phosphatidylcholine intramembrane carrier activity#GO:0008525;molecular carrier activity#GO:0140104;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000016691.1|UniProtKB=W5NJ17 W5NJ17 PTHR15508:SF2 RIBOSOMAL PROTEIN S6 KINASE INACTIVE RIBOSOMAL PROTEIN S6 KINASE DELTA-1 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 PDGF signaling pathway#P00047>p90RSK#P01142 LEPOC|Ensembl=ENSLOCG00000006349.1|UniProtKB=W5MH03 W5MH03 PTHR24082:SF509 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1, GROUP H, MEMBER 3 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 negative regulation of response to external stimulus#GO:0032102;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;chemical homeostasis#GO:0048878;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;lipid homeostasis#GO:0055088;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;cholesterol homeostasis#GO:0042632;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;homeostatic process#GO:0042592;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000016849.1|UniProtKB=W5NJL6 W5NJL6 PTHR11972:SF12 NADPH OXIDASE NADPH OXIDASE 3 catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 defense response#GO:0006952;superoxide metabolic process#GO:0006801;response to stimulus#GO:0050896;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to stress#GO:0006950 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000011854.1|UniProtKB=W5N1S5 W5N1S5 PTHR24056:SF510 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000004326.1|UniProtKB=W5M9V8 W5M9V8 PTHR23007:SF13 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL protein kinase binding#GO:0019901;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane raft#GO:0045121;cell periphery#GO:0071944;membrane microdomain#GO:0098857 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000005444.1|UniProtKB=W5MDV2 W5MDV2 PTHR22426:SF2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000015225.1|UniProtKB=W5NDM7 W5NDM7 PTHR10747:SF33 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 P53-like transcription factor#PC00253;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011930.1|UniProtKB=W5N220 W5N220 PTHR12582:SF4 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5A transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular process#GO:0009987;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 LEPOC|Ensembl=ENSLOCG00000006847.1|UniProtKB=W5MIS4 W5MIS4 PTHR15271:SF4 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;nucleosome organization#GO:0034728;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012317.1|UniProtKB=W5N3G5 W5N3G5 PTHR10514:SF51 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;system process#GO:0003008;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;peptide hormone processing#GO:0016486;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;biosynthetic process#GO:0009058;biological regulation#GO:0065007;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;blood circulation#GO:0008015;hormone metabolic process#GO:0042445;circulatory system process#GO:0003013;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;positive regulation of blood pressure#GO:0045777 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000016812.1|UniProtKB=W5NJG9 W5NJG9 PTHR11685:SF99 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF144A protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005754.1|UniProtKB=W5MEY6 W5MEY6 PTHR23415:SF30 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047 mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle phase transition#GO:0044772 nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010327.1|UniProtKB=W5MWA2 W5MWA2 PTHR23280:SF4 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 4A actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000014187.1|UniProtKB=W5NA16 W5NA16 PTHR21230:SF89 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B binding#GO:0005488;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 membrane organization#GO:0061024;macroautophagy#GO:0016236;retrograde transport, endosome to Golgi#GO:0042147;membrane fusion#GO:0061025;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;vesicle fusion#GO:0006906;catabolic process#GO:0009056;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;endosomal transport#GO:0016197;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;metabolic process#GO:0008152;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;post-Golgi vesicle-mediated transport#GO:0006892;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641 bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;endoplasmic reticulum#GO:0005783;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;ER to Golgi transport vesicle membrane#GO:0012507;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;SNARE complex#GO:0031201;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982 SNARE protein#PC00034;membrane traffic protein#PC00150 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 LEPOC|Ensembl=ENSLOCG00000010188.1|UniProtKB=W5MVR4 W5MVR4 PTHR24353:SF160 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell adhesion#GO:0007155;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;GABA-B receptor II signaling#P05731>PKA#P05752;Endothelin signaling pathway#P00019>PKA#P00570;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862 LEPOC|Ensembl=ENSLOCG00000016040.1|UniProtKB=W5NGJ9 W5NGJ9 PTHR15583:SF10 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR E-LIKE PROTEIN cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001782.1|UniProtKB=W5M107 W5M107 PTHR20932:SF5 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 3-RELATED endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000018134.1|UniProtKB=W5NNM6 W5NNM6 PTHR10489:SF733 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 4 signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;chemotaxis#GO:0006935 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000007647.1|UniProtKB=W5MLL6 W5MLL6 PTHR10352:SF15 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 3 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000012403.1|UniProtKB=W5N3R2 W5N3R2 PTHR10005:SF7 SKI ONCOGENE-RELATED SKI FAMILY TRANSCRIPTIONAL COREPRESSOR 2 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of BMP signaling pathway#GO:0030510;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;negative regulation of BMP signaling pathway#GO:0030514;regulation of gene expression#GO:0010468;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000004786.1|UniProtKB=W5MBL9 W5MBL9 PTHR46360:SF1 DISKS LARGE HOMOLOG 5 DISKS LARGE HOMOLOG 5 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005630.1|UniProtKB=W5MEJ5 W5MEJ5 PTHR24031:SF89 RNA HELICASE ATP-DEPENDENT DNA HELICASE DDX31 ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000892.1|UniProtKB=W5LXY3 W5LXY3 PTHR10489:SF944 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 8 cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515 calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;chemotaxis#GO:0006935;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000376.1|UniProtKB=W5LWA4 W5LWA4 PTHR46182:SF3 FI19480P1 DYSLEXIA-ASSOCIATED PROTEIN KIAA0319-LIKE PROTEIN animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;developmental process#GO:0032502;multicellular organism development#GO:0007275;neuron migration#GO:0001764;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;cellular process#GO:0009987;cell differentiation#GO:0030154;cell motility#GO:0048870;multicellular organismal process#GO:0032501;cell migration#GO:0016477;nervous system development#GO:0007399 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000003492.1|UniProtKB=W5M6X8 W5M6X8 PTHR21017:SF11 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;mitophagy#GO:0000423;process utilizing autophagic mechanism#GO:0061919;cellular process#GO:0009987;autophagy#GO:0006914;catabolic process#GO:0009056;macroautophagy#GO:0016236 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000004156.1|UniProtKB=W5M9B5 W5M9B5 PTHR11388:SF142 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 5A1 active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003239.1|UniProtKB=W5M617 W5M617 PTHR12011:SF454 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G2 ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011328.1|UniProtKB=W5MZW1 W5MZW1 PTHR22974:SF20 MIXED LINEAGE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TOUSLED-LIKE 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell cycle#GO:0007049;chromosome segregation#GO:0007059;cellular process#GO:0009987;cell cycle process#GO:0022402 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000003112.1|UniProtKB=W5M5L2 W5M5L2 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017736.1|UniProtKB=W5NMI1 W5NMI1 PTHR23226:SF248 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 648 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000017145.1|UniProtKB=W5NKN9 W5NKN9 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012397.1|UniProtKB=W5N3R0 W5N3R0 PTHR43512:SF7 TRANSLATION FACTOR GUF1-RELATED TRANSLATION FACTOR GUF1, MITOCHONDRIAL binding#GO:0005488;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021 biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000010935.1|UniProtKB=W5MYF1 W5MYF1 PTHR24161:SF129 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED REPEAT PROTEIN, PUTATIVE-RELATED protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001373.1|UniProtKB=W5LZJ9 W5LZJ9 PTHR11106:SF93 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED ADP-RIBOSE GLYCOHYDROLASE MACROD1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 nucleoside metabolic process#GO:0009116;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine nucleoside metabolic process#GO:0042278;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000491.1|UniProtKB=W5LWN5 W5LWN5 PTHR36681:SF3 NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3 NUCLEAR GTPASE, GERMINAL CENTER ASSOCIATED, TANDEM DUPLICATE 3 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000003006.1|UniProtKB=W5M5B9 W5M5B9 PTHR12752:SF14 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 7-RELATED LEPOC|Ensembl=ENSLOCG00000004049.1|UniProtKB=W5M8X9 W5M8X9 PTHR44656:SF6 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 12 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 12 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000014387.1|UniProtKB=W5NAQ3 W5NAQ3 PTHR45623:SF19 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD2 protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;ATP hydrolysis activity#GO:0016887;DNA binding#GO:0003677;hydrolase activity#GO:0016787;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640 protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;nucleosome organization#GO:0034728;cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004787.1|UniProtKB=W5MBI5 W5MBI5 PTHR10332:SF93 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4 nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;active transmembrane transporter activity#GO:0022804;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008773.1|UniProtKB=W5MQL6 W5MQL6 PTHR21454:SF31 DPH3 HOMOLOG-RELATED DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3 transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;iron ion binding#GO:0005506 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;metabolic process#GO:0008152;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000010419.1|UniProtKB=W5MWL7 W5MWL7 PTHR11711:SF21 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 organelle assembly#GO:0070925;protein transport#GO:0015031;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;transport#GO:0006810;intracellular protein transport#GO:0006886;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000016322.1|UniProtKB=W5NHP2 W5NHP2 PTHR23104:SF14 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010546.1|UniProtKB=W5MX18 W5MX18 PTHR12904:SF22 FAMILY NOT NAMED ZYG-11 FAMILY MEMBER A, CELL CYCLE REGULATOR protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462 LEPOC|Ensembl=ENSLOCG00000008868.1|UniProtKB=W5MQY7 W5MQY7 PTHR22726:SF1 METALLOENDOPEPTIDASE OMA1 METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004799.1|UniProtKB=W5MBL3 W5MBL3 PTHR13167:SF40 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 biological regulation#GO:0065007;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;regulation of biological quality#GO:0065008;response to external stimulus#GO:0009605;regulation of membrane potential#GO:0042391;cellular response to abiotic stimulus#GO:0071214;detection of mechanical stimulus#GO:0050982 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017284.1|UniProtKB=W5NL72 W5NL72 PTHR15215:SF1 CABIT DOMAIN-CONTAINING PROTEIN PROTEIN THEMIS positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;antigen receptor-mediated signaling pathway#GO:0050851;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;immune system process#GO:0002376;regulation of immune response#GO:0050776;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000005879.1|UniProtKB=W5MFE0 W5MFE0 PTHR36542:SF8 GIG2-LIKE PROTEIN DRED-RELATED GIG2-LIKE PROTEIN DREN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004804.1|UniProtKB=W5MBL1 W5MBL1 dis3l2 PTHR23355:SF68 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 2 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000012007.1|UniProtKB=W5N2A6 W5N2A6 PTHR43601:SF39 THIOREDOXIN, MITOCHONDRIAL THIOREDOXIN, MITOCHONDRIAL cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 LEPOC|Ensembl=ENSLOCG00000006167.1|UniProtKB=W5MGE0 W5MGE0 PTHR12756:SF41 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 2 catalytic activity#GO:0003824;tubulin binding#GO:0015631;metalloexopeptidase activity#GO:0008235;cytoskeletal protein binding#GO:0008092;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;binding#GO:0005488;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;protein binding#GO:0005515;carboxypeptidase activity#GO:0004180 organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000006438.1|UniProtKB=W5MHC3 W5MHC3 PTHR13028:SF0 RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED RRNA-PROCESSING PROTEIN EBP2-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000002942.1|UniProtKB=W5M513 W5M513 PTHR15592:SF17 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 3 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000004836.1|UniProtKB=W5MBQ4 W5MBQ4 CTU2 PTHR20882:SF14 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA wobble position uridine thiolation#GO:0002143;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;tRNA thio-modification#GO:0034227;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010825.1|UniProtKB=W5MY12 W5MY12 PTHR23282:SF137 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000003739.1|UniProtKB=W5M7U6 W5M7U6 PTHR12865:SF7 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 endomembrane system organization#GO:0010256;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637;endosome organization#GO:0007032;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;Golgi organization#GO:0007030;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endosome#GO:0005768;intracellular organelle#GO:0043229;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;Golgi apparatus#GO:0005794 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006024.1|UniProtKB=W5MFW7 W5MFW7 PTHR45915:SF1 TRANSCRIPTION INTERMEDIARY FACTOR BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012884.1|UniProtKB=W5N5F3 W5N5F3 PTHR24399:SF28 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 25 sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012748.1|UniProtKB=W5N4X3 W5N4X3 PTHR16057:SF1 WINS1, 2 PROTEIN PROTEIN LINES HOMOLOG 1 LEPOC|Ensembl=ENSLOCG00000013466.1|UniProtKB=W5N7J9 W5N7J9 PTHR13475:SF5 NEUGRIN TUBULIN TYROSINE LIGASE LIKE 13 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;mitochondrial ribosome assembly#GO:0061668;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000008117.1|UniProtKB=W5MN98 W5MN98 PTHR24409:SF324 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 131 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008642.1|UniProtKB=W5MQ43 W5MQ43 PTHR11860:SF120 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 5-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017183.1|UniProtKB=W5NKS9 W5NKS9 PTHR47696:SF4 THAP DOMAIN-CONTAINING PROTEIN 2 THAP DOMAIN CONTAINING 2 LEPOC|Ensembl=ENSLOCG00000005037.1|UniProtKB=W5MCF9 W5MCF9 PTHR14014:SF0 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 1 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 1 localization#GO:0051179;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;telomere tethering at nuclear periphery#GO:0034398;nuclear division#GO:0000280;organelle localization#GO:0051640;sexual reproduction#GO:0019953;reproductive process#GO:0022414;telomere localization#GO:0034397;cell cycle#GO:0007049;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;homologous chromosome pairing at meiosis#GO:0007129;chromosome localization#GO:0050000;organelle organization#GO:0006996;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000007215.1|UniProtKB=W5MK22 W5MK22 PTHR31981:SF1 GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 LEPOC|Ensembl=ENSLOCG00000007008.1|UniProtKB=W5MJC7 W5MJC7 PTHR24240:SF189 OPSIN TELEOST MULTIPLE TISSUE OPSIN A transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to radiation#GO:0071478;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628 cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012791.1|UniProtKB=W5N532 W5N532 PTHR11937:SF575 ACTIN ACTIN, CYTOPLASMIC 2 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918;structural constituent of cytoskeleton#GO:0005200 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;actin filament#GO:0005884;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114 LEPOC|Ensembl=ENSLOCG00000000993.1|UniProtKB=W5LYA9 W5LYA9 PTHR13999:SF31 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN IFITM1-RELATED defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000733.1|UniProtKB=W5LXG0 W5LXG0 PTHR28080:SF1 PEROXISOMAL BIOGENESIS FACTOR 3 PEROXISOMAL BIOGENESIS FACTOR 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;peroxisome organization#GO:0007031;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;peroxisomal transport#GO:0043574;protein transport#GO:0015031;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;protein localization to organelle#GO:0033365 membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000004176.1|UniProtKB=W5M9C9 W5M9C9 PTHR45704:SF3 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE PROTEIN FAMILY MEMBER 11A LEPOC|Ensembl=ENSLOCG00000017360.1|UniProtKB=W5NLF6 W5NLF6 PTHR45712:SF12 AGAP008170-PA LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT3 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011690.1|UniProtKB=W5N153 W5N153 PTHR24228:SF49 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN RECEPTOR TYPE 1A LIKE transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015334.1|UniProtKB=W5NE07 W5NE07 PTHR24070:SF388 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE KRAS pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;Integrin signalling pathway#P00034>Ras#P00916;Ras Pathway#P04393>Ras#P04547;EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;PDGF signaling pathway#P00047>Ras#P01154;FGF signaling pathway#P00021>Ras#P00633;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;p53 pathway feedback loops 2#P04398>Ras#P04651;Angiogenesis#P00005>Ras#P00238;PI3 kinase pathway#P00048>Ras#P01182 LEPOC|Ensembl=ENSLOCG00000015283.1|UniProtKB=W5NDU4 W5NDU4 PTHR15852:SF49 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN PROTEIN SSUH2 HOMOLOG LEPOC|Ensembl=ENSLOCG00000010735.1|UniProtKB=W5MXP2 W5MXP2 PTHR21707:SF42 FLAGELLUM-ASSOCIATED COILED-COIL DOMAIN-CONTAINING PROTEIN 1 FLAGELLUM-ASSOCIATED COILED-COIL DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001580.1|UniProtKB=W5M0A4 W5M0A4 PTHR11866:SF31 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;negative regulation of response to external stimulus#GO:0032102;cellular response to lipid#GO:0071396;regulation of response to external stimulus#GO:0032101;response to lipid#GO:0033993;response to chemical#GO:0042221;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to alcohol#GO:0097305;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of response to stress#GO:0080134;cellular response to alcohol#GO:0097306;cellular response to stimulus#GO:0051716;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009088.1|UniProtKB=W5MRR8 W5MRR8 PTHR24173:SF27 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014202.1|UniProtKB=W5NA34 W5NA34 PTHR47410:SF4 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 9 ISOFORM X1 pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;defense response to virus#GO:0051607;toll-like receptor signaling pathway#GO:0002224;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;positive regulation of multicellular organismal process#GO:0051240;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;response to virus#GO:0009615;intracellular signal transduction#GO:0035556;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;canonical NF-kappaB signal transduction#GO:0007249;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of cytokine production#GO:0001817;activation of innate immune response#GO:0002218;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004258.1|UniProtKB=W5M9N4 W5M9N4 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007261.1|UniProtKB=W5MK75 W5MK75 PTHR10686:SF44 FOLATE TRANSPORTER SOLUTE CARRIER FAMILY 19 MEMBER 3A transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017057.1|UniProtKB=W5NKB8 W5NKB8 PTHR15742:SF2 GIRDIN MICROTUBULE CROSS-LINKING FACTOR 3 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000010599.1|UniProtKB=W5MX88 W5MX88 PTHR33724:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641 membrane-bounded organelle#GO:0043227;intraciliary transport particle A#GO:0030991;cilium#GO:0005929;intraciliary transport particle#GO:0030990;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000006181.1|UniProtKB=W5MGF9 W5MGF9 PTHR24366:SF171 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC33 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000013406.1|UniProtKB=W5N7C3 W5N7C3 PTHR23324:SF51 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000003831.1|UniProtKB=W5M863 W5M863 PTHR11339:SF420 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED IGGFC-BINDING PROTEIN-RELATED structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000009697.1|UniProtKB=W5MTY6 W5MTY6 PTHR15136:SF2 STROMAL INTERACTION MOLECULE HOMOLOG STROMAL INTERACTION MOLECULE 2 metal ion binding#GO:0046872;channel regulator activity#GO:0016247;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transporter regulator activity#GO:0141108;calcium ion binding#GO:0005509;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion homeostasis#GO:0050801;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009348.1|UniProtKB=W5MSP7 W5MSP7 PTHR24339:SF26 HOMEOBOX PROTEIN EMX-RELATED HOMEOBOX PROTEIN EMX1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 head development#GO:0060322;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015889.1|UniProtKB=W5NG07 W5NG07 PTHR14582:SF1 INNER KINETOCHORE SUBUNIT MAL2 CENTROMERE PROTEIN O condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000011727.1|UniProtKB=W5N1A6 W5N1A6 PTHR10417:SF3 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000002477.1|UniProtKB=W5M3E6 W5M3E6 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003494.1|UniProtKB=W5M6Y4 W5M6Y4 PTHR46806:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN DISCOIDIN, CUB AND LCCL DOMAIN CONTAINING 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000003058.1|UniProtKB=W5M5E1 W5M5E1 PTHR46052:SF4 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN-LIKE PROTEIN protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001529.1|UniProtKB=W5M057 W5M057 PTHR12606:SF10 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 5 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016648.1|UniProtKB=W5NIV6 W5NIV6 PTHR12197:SF288 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD HISTONE-LYSINE N-METHYLTRANSFERASE SMYD3 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;histone H3K36 methyltransferase activity#GO:0046975;catalytic activity, acting on a protein#GO:0140096 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;heart development#GO:0007507;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;circulatory system development#GO:0072359;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000018009.1|UniProtKB=W5NNA1 W5NNA1 PTHR15065:SF5 INSULINOMA-ASSOCIATED 1 INSULINOMA-ASSOCIATED PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067 negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cell cycle#GO:0051726;negative regulation of metabolic process#GO:0009892 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000013615.1|UniProtKB=W5N824 W5N824 PTHR11683:SF4 MYELIN PROTEOLIPID NEURONAL MEMBRANE GLYCOPROTEIN M6-A biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;regulation of filopodium assembly#GO:0051489;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of cell projection organization#GO:0031344;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;regulation of cell projection assembly#GO:0060491;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;filopodium#GO:0030175;growth cone#GO:0030426;axonal growth cone#GO:0044295;intracellular organelle#GO:0043229;axon#GO:0030424;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuronal cell body#GO:0043025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cell body#GO:0044297;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000009976.1|UniProtKB=W5MUZ1 W5MUZ1 PTHR10621:SF13 UV EXCISION REPAIR PROTEIN RAD23 LYSINE-SPECIFIC DEMETHYLASE RAD23B protein binding#GO:0005515;protein-containing complex binding#GO:0044877;modification-dependent protein binding#GO:0140030;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;ubiquitin binding#GO:0043130 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000000655.1|UniProtKB=W5LX69 W5LX69 PTHR11932:SF174 CULLIN CULLIN-2 enzyme binding#GO:0019899;protein complex scaffold activity#GO:0140378;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625;structural molecule activity#GO:0005198;protein binding#GO:0005515 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000006916.1|UniProtKB=W5MJ11 W5MJ11 PTHR14516:SF2 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER NON-HOMOLOGOUS END JOINING FACTOR IFFO1 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000009182.1|UniProtKB=W5MS38 W5MS38 PTHR12263:SF5 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT E 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex#GO:0016469;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;membrane#GO:0016020;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773 ATP synthase#PC00002;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000015581.1|UniProtKB=W5NEX3 W5NEX3 PTHR31283:SF5 EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER L ANTIGEN FAMILY MEMBER 3 protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000003376.1|UniProtKB=W5M6K5 W5M6K5 PTHR23192:SF68 OLFACTOMEDIN-RELATED OLFACTOMEDIN-4-RELATED cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014410.1|UniProtKB=W5NAT1 W5NAT1 PTHR11844:SF26 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 4 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;negative regulation of catabolic process#GO:0009895;response to peptide#GO:1901652;regulation of protein catabolic process#GO:0042176;response to cytokine#GO:0034097;response to chemical#GO:0042221;negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;response to hormone#GO:0009725;negative regulation of macromolecule metabolic process#GO:0010605;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015024.1|UniProtKB=W5NCY9 W5NCY9 PTHR28657:SF4 INDOLEAMINE 2,3-DIOXYGENASE INDOLEAMINE 2,3-DIOXYGENASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;nicotinamide nucleotide metabolic process#GO:0046496;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;indole-containing compound metabolic process#GO:0042430;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000006918.1|UniProtKB=W5MJ26 W5MJ26 PTHR12215:SF10 PHOSPHOPANTETHEINE TRANSFERASE L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009543.1|UniProtKB=W5MTF1 W5MTF1 PTHR11937:SF575 ACTIN ACTIN, CYTOPLASMIC 2 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 actin cytoskeleton#GO:0015629;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Huntington disease#P00029>Actin#P00807;Integrin signalling pathway#P00034>Actin#P00944;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Alzheimer disease-presenilin pathway#P00004>actin#P00114 LEPOC|Ensembl=ENSLOCG00000008148.1|UniProtKB=W5MND2 W5MND2 PTHR46916:SF2 TRANSMEMBRANE PROTEIN 205 TRANSMEMBRANE PROTEIN 205 LEPOC|Ensembl=ENSLOCG00000008027.1|UniProtKB=W5MN05 W5MN05 EEF1AKMT2 PTHR12843:SF5 PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10 EEF1A LYSINE METHYLTRANSFERASE 2 protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006344.1|UniProtKB=W5MGZ8 W5MGZ8 PTHR11654:SF684 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 4 oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;import across plasma membrane#GO:0098739;transport#GO:0006810;oligopeptide transport#GO:0006857;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;dipeptide transport#GO:0042938 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004052.1|UniProtKB=W5M900 W5M900 PTHR44298:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 protein binding#GO:0005515;binding#GO:0005488 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000152.1|UniProtKB=W5LVK9 W5LVK9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000649.1|UniProtKB=W5LX60 W5LX60 PTHR22708:SF0 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56 LEPOC|Ensembl=ENSLOCG00000008793.1|UniProtKB=W5MQQ2 W5MQQ2 PTHR12296:SF18 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN 4B guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of biological process#GO:0050789;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000005398.1|UniProtKB=W5MDQ3 W5MDQ3 PTHR46295:SF1 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 LEPOC|Ensembl=ENSLOCG00000010009.1|UniProtKB=W5MV48 W5MV48 PTHR45796:SF3 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P1 DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000005432.1|UniProtKB=W5MDU5 W5MDU5 PTHR24416:SF349 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE RYK transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of intracellular signal transduction#GO:1902531;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006624.1|UniProtKB=W5MI07 W5MI07 PTHR23108:SF0 METHYLTRANSFERASE-RELATED METHYLTRANSFERASE-LIKE PROTEIN 22 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000006405.1|UniProtKB=W5MH79 W5MH79 PTHR11760:SF76 30S/40S RIBOSOMAL PROTEIN S3 SMALL RIBOSOMAL SUBUNIT PROTEIN US3 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of programmed cell death#GO:0043067;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000007445.1|UniProtKB=W5MKX1 W5MKX1 PTHR20996:SF1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 intracellular anatomical structure#GO:0005622;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;membrane protein complex#GO:0098796 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000007966.1|UniProtKB=W5MMR6 W5MMR6 PTHR15736:SF2 PROTEIN FAM131B-RELATED PROTEIN FAM131C LEPOC|Ensembl=ENSLOCG00000012424.1|UniProtKB=W5N3T8 W5N3T8 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 LEPOC|Ensembl=ENSLOCG00000000422.1|UniProtKB=W5LWF4 W5LWF4 PTHR10811:SF110 FRINGE-RELATED BETA-1,3-GLUCOSYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000012452.1|UniProtKB=W5N3X3 W5N3X3 PTHR18034:SF4 CELL CYCLE CONTROL PROTEIN CWF22-RELATED NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000001333.1|UniProtKB=W5LZG5 W5LZG5 PTHR36754:SF2 E3 UBIQUITIN-PROTEIN LIGASE TRIM37 E3 UBIQUITIN-PROTEIN LIGASE TRIM37 ubiquitin-like protein ligase binding#GO:0044389;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin protein ligase binding#GO:0031625;catalytic activity, acting on a protein#GO:0140096;tumor necrosis factor receptor superfamily binding#GO:0032813;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;signaling receptor binding#GO:0005102;transferase activity#GO:0016740;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;binding#GO:0005488;cytokine receptor binding#GO:0005126;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;cellular component assembly#GO:0022607;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular component biogenesis#GO:0044085;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular component organization#GO:0016043;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000002390.1|UniProtKB=W5M341 W5M341 PTHR19854:SF1 TRANSDUCIN BETA-LIKE 3 GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002019.1|UniProtKB=W5M1T3 W5M1T3 PTHR11848:SF29 TGF-BETA FAMILY INHIBIN BETA B CHAIN signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inhba/b#P06700;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000015704.1|UniProtKB=W5NFC2 W5NFC2 PTHR22799:SF1 TETRANECTIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 11 MEMBER A molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083 ossification#GO:0001503;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016535.1|UniProtKB=W5NIG2 W5NIG2 PTHR12101:SF18 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 3 nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553 regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;muscle structure development#GO:0061061;cell differentiation#GO:0030154;circulatory system development#GO:0072359;muscle cell differentiation#GO:0042692;striated muscle cell differentiation#GO:0051146;cellular developmental process#GO:0048869;regulation of membrane potential#GO:0042391;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 sarcolemma#GO:0042383;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000008856.1|UniProtKB=W5MQW2 W5MQW2 PTHR16076:SF8 CYTOSKELETON ASSOCIATED PROTEIN 2-RELATED CYTOSKELETON-ASSOCIATED PROTEIN 2 regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;negative regulation of cellular process#GO:0048523;negative regulation of protein depolymerization#GO:1901880;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;regulation of protein-containing complex disassembly#GO:0043244;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000002618.1|UniProtKB=W5M435 W5M435 PTHR10336:SF25 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2 phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity#GO:0016787;lipase activity#GO:0016298 positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;monoatomic ion transmembrane transport#GO:0034220;regulation of cell migration#GO:0030334;transport#GO:0006810;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;positive regulation of locomotion#GO:0040017;establishment of localization#GO:0051234;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell motility#GO:2000145;localization#GO:0051179;monoatomic cation transport#GO:0006812;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;monoatomic cation transmembrane transport#GO:0098655;regulation of multicellular organismal process#GO:0051239;glycerophospholipid metabolic process#GO:0006650;metabolic process#GO:0008152;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection membrane#GO:0031253;ruffle#GO:0001726;leading edge membrane#GO:0031256;ruffle membrane#GO:0032587 hydrolase#PC00121;lipase#PC00143;phospholipase#PC00186;metabolite interconversion enzyme#PC00262 VEGF signaling pathway#P00056>PLC-gamma#P01414;FGF signaling pathway#P00021>PLCgamma#P00638;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;B cell activation#P00010>PLC gamma2#P00388;Angiogenesis#P00005>PLC-gamma#P00256;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362;EGF receptor signaling pathway#P00018>PLCgamma#P00556;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;PDGF signaling pathway#P00047>PLCgamma#P01171;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412 LEPOC|Ensembl=ENSLOCG00000008767.1|UniProtKB=W5MQM6 W5MQM6 PTHR11596:SF76 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME ISOFORM X1 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 ossification#GO:0001503;multicellular organismal process#GO:0032501;tissue development#GO:0009888;animal gross anatomical part developmental process#GO:0160108;bone mineralization#GO:0030282;biomineral tissue development#GO:0031214;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000013007.1|UniProtKB=W5N5X1 W5N5X1 PTHR12710:SF0 NUCLEAR PROTEIN LOCALIZATION 4 NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;response to endoplasmic reticulum stress#GO:0034976;response to stimulus#GO:0050896;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 LEPOC|Ensembl=ENSLOCG00000011575.1|UniProtKB=W5N0S0 W5N0S0 PTHR14555:SF6 MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED RAB EFFECTOR MYRIP protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000015005.1|UniProtKB=W5NCW6 W5NCW6 PTHR22761:SF21 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 7 establishment of localization#GO:0051234;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;nuclear membrane organization#GO:0071763;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;membrane assembly#GO:0071709 nuclear envelope#GO:0005635;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic side of membrane#GO:0098562;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;side of membrane#GO:0098552;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005079.1|UniProtKB=W5MCK9 W5MCK9 PTHR13096:SF7 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 2 LEPOC|Ensembl=ENSLOCG00000016491.1|UniProtKB=W5NIB1 W5NIB1 PTHR10159:SF343 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 16 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824 negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000009812.1|UniProtKB=W5MUD5 W5MUD5 PTHR11521:SF5 TROPONIN T TROPONIN T, CARDIAC MUSCLE protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;heart process#GO:0003015;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;heart contraction#GO:0060047;system process#GO:0003008;cellular developmental process#GO:0048869;muscle contraction#GO:0006936;developmental process#GO:0032502;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cardiac muscle contraction#GO:0060048;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001 myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000009245.1|UniProtKB=W5MSB5 W5MSB5 PTHR24208:SF116 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX4 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014043.1|UniProtKB=W5N9K3 W5N9K3 PTHR46055:SF2 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 Circadian clock system#P00015>Clock#P00501 LEPOC|Ensembl=ENSLOCG00000016676.1|UniProtKB=W5NIZ6 W5NIZ6 PTHR45627:SF15 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016 cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 adenylate cyclase#PC00043 LEPOC|Ensembl=ENSLOCG00000004983.1|UniProtKB=W5MC91 W5MC91 PTHR24027:SF424 CADHERIN-23 CADHERIN-16 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell motility#GO:0048870;cell migration#GO:0016477;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000001583.1|UniProtKB=W5M0B0 W5M0B0 PTHR15225:SF8 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN RNA-BINDING PROTEIN 43 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000001567.1|UniProtKB=W5M085 W5M085 PTHR10159:SF108 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 8 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000007130.1|UniProtKB=W5MJS1 W5MJS1 PTHR18952:SF110 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 6 catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000005979.1|UniProtKB=W5MFR3 W5MFR3 PTHR46096:SF5 PERFORIN-1 PERFORIN 1.7-RELATED passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cell-cell recognition#GO:0009988;defense response#GO:0006952;response to external stimulus#GO:0009605;cell killing#GO:0001906;immune effector process#GO:0002252;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;response to other organism#GO:0051707;adaptive immune response#GO:0002250;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;immune response#GO:0006955;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;response to virus#GO:0009615;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;cell activation#GO:0001775;cell recognition#GO:0008037;T cell mediated immunity#GO:0002456;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;leukocyte mediated cytotoxicity#GO:0001909;leukocyte activation#GO:0045321;defense response to virus#GO:0051607 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000014650.1|UniProtKB=W5NBM2 W5NBM2 PTHR22847:SF736 WD40 REPEAT PROTEIN F-BOX DOMAIN-CONTAINING PROTEIN intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006168.1|UniProtKB=W5MGE8 W5MGE8 PTHR12106:SF50 SORTILIN RELATED SORTILIN-RELATED RECEPTOR protein localization to organelle#GO:0033365;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;protein localization to lysosome#GO:0061462;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;localization#GO:0051179;lysosomal transport#GO:0007041;protein localization to vacuole#GO:0072665;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;protein localization to Golgi apparatus#GO:0034067 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009450.1|UniProtKB=W5MT28 W5MT28 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017519.1|UniProtKB=W5NLW5 W5NLW5 PTHR24369:SF217 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE RICH REPEAT CONTAINING 3C cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000010868.1|UniProtKB=W5MY77 W5MY77 PTHR11824:SF9 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2 chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 voltage-gated ion channel#PC00241 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438 LEPOC|Ensembl=ENSLOCG00000010528.1|UniProtKB=W5MWZ3 W5MWZ3 PTHR19143:SF25 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000002626.1|UniProtKB=W5M3Y3 W5M3Y3 PTHR15741:SF27 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR AP-4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001385.1|UniProtKB=W5LZP1 W5LZP1 PTHR10199:SF88 THROMBOSPONDIN CARTILAGE OLIGOMERIC MATRIX PROTEIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;connective tissue development#GO:0061448;tissue development#GO:0009888;anatomical structure development#GO:0048856 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012928.1|UniProtKB=W5N5K9 W5N5K9 PTHR14388:SF7 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 4B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006242.1|UniProtKB=W5MGM9 W5MGM9 PTHR12411:SF929 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN Z peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007785.1|UniProtKB=W5MM55 W5MM55 PTHR14049:SF14 LEPRECAN 1 PROLYL 3-HYDROXYLASE 3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000013682.1|UniProtKB=W5N8B0 W5N8B0 PTHR14791:SF26 BOMB/KIRA PROTEINS PROTEIN WWC2 protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 regulation of biological process#GO:0050789;regulation of growth#GO:0040008;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell migration#GO:0016477;regulation of response to stimulus#GO:0048583;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000007348.1|UniProtKB=W5MKJ5 W5MKJ5 PTHR13771:SF9 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 1 ISOFORM X1-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000013315.1|UniProtKB=W5N717 W5N717 PTHR23220:SF89 INTEGRIN ALPHA INTEGRIN ALPHA-3 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000015560.1|UniProtKB=W5NEU4 W5NEU4 PTHR24103:SF667 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM69 ISOFORM X1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003225.1|UniProtKB=W5M629 W5M629 PTHR23138:SF186 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3-RELATED localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;protein export from nucleus#GO:0006611;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012636.1|UniProtKB=W5N4K4 W5N4K4 PTHR11036:SF17 SEMAPHORIN SEMAPHORIN-4G signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to chemical#GO:0042221;taxis#GO:0042330;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;locomotion#GO:0040011;chemotaxis#GO:0006935;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000005345.1|UniProtKB=W5MDI7 W5MDI7 PANX PTHR15759:SF3 PANNEXIN PANNEXIN-3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000377.1|UniProtKB=W5LWA3 W5LWA3 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010889.1|UniProtKB=W5MY97 W5MY97 PTHR12191:SF4 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP12 secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;zinc ion transmembrane transporter activity#GO:0005385;bicarbonate transmembrane transporter activity#GO:0015106;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004027.1|UniProtKB=W5M8V8 W5M8V8 PTHR10805:SF0 COATOMER SUBUNIT EPSILON COATOMER SUBUNIT EPSILON establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890 cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;COPI-coated vesicle#GO:0030137;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000006674.1|UniProtKB=W5MI49 W5MI49 PTHR12889:SF1 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;signal transduction#GO:0007165;protein metabolic process#GO:0019538;cell communication#GO:0007154;proteolysis#GO:0006508;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>Aph-1#P00091;Notch signaling pathway#P00045>Aph-1#P01109;Alzheimer disease-presenilin pathway#P00004>Aph-1#P00170 LEPOC|Ensembl=ENSLOCG00000004356.1|UniProtKB=W5M9Z4 W5M9Z4 PTHR10553:SF44 SMALL NUCLEAR RIBONUCLEOPROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 U6 snRNP#GO:0005688;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U2-type prespliceosome#GO:0071004 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000017273.1|UniProtKB=W5NL56 W5NL56 PTHR20859:SF55 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON LAMBDA RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013847.1|UniProtKB=W5N8W9 W5N8W9 PTHR46389:SF1 POLYCOMB GROUP PROTEIN PC CHROMOBOX PROTEIN HOMOLOG 8 chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 transferase complex#GO:1990234;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004208.1|UniProtKB=W5M9H2 W5M9H2 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002606.1|UniProtKB=W5M3V7 W5M3V7 PTHR20935:SF0 PHOSPHOGLYCERATE MUTASE-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 biological regulation#GO:0065007;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;regulation of developmental process#GO:0050793;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of mitochondrion organization#GO:0010821;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of organelle organization#GO:0033043;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;positive regulation of developmental process#GO:0051094 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 isomerase#PC00135;mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000006591.1|UniProtKB=W5MHV3 W5MHV3 PTHR24073:SF1247 DRAB5-RELATED SMALL MONOMERIC GTPASE ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 import into cell#GO:0098657;establishment of localization#GO:0051234;regulation of neuronal synaptic plasticity#GO:0048168;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;regulation of synaptic plasticity#GO:0048167;transport#GO:0006810;intracellular protein transport#GO:0006886;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological quality#GO:0065008;protein transport#GO:0015031;regulation of signaling#GO:0023051;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of biological process#GO:0050789 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;axon#GO:0030424;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endocytic vesicle#GO:0030139 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000004201.1|UniProtKB=W5M9H5 W5M9H5 PTHR46877:SF18 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 4 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485 somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013333.1|UniProtKB=W5N724 W5N724 PTHR24350:SF4 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE B protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;microtubule cytoskeleton organization#GO:0000226;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cellular process#GO:0009987;organelle organization#GO:0006996;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spindle pole#GO:0000922;chromosome#GO:0005694;midbody#GO:0030496;kinetochore#GO:0000776;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002811.1|UniProtKB=W5M4K6 W5M4K6 PTHR11732:SF527 ALDO/KETO REDUCTASE ALCOHOL DEHYDROGENASE (NADP(+)) alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007000.1|UniProtKB=W5MJB5 W5MJB5 PTHR12289:SF38 METAXIN RELATED METAXIN-2 establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;protein-containing complex assembly#GO:0065003 mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006954.1|UniProtKB=W5MJ49 W5MJ49 PTHR33968:SF1 PROTEIN PET100 HOMOLOG, MITOCHONDRIAL PROTEIN PET100 HOMOLOG, MITOCHONDRIAL cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;chaperone-mediated protein complex assembly#GO:0051131;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607 organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000017955.1|UniProtKB=W5NN49 W5NN49 PTHR11863:SF104 STEROL DESATURASE CHOLESTEROL 25-HYDROXYLASE-LIKE PROTEIN 1, MEMBER 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497 cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;secondary alcohol biosynthetic process#GO:1902653;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000010010.1|UniProtKB=W5MV35 W5MV35 PTHR12999:SF26 ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 lipopolysaccharide binding#GO:0001530;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;lipid binding#GO:0008289 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000012076.1|UniProtKB=W5N2L0 W5N2L0 PTHR46145:SF3 HEPARANASE HEPARANASE blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;circulatory system development#GO:0072359;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731;wound healing#GO:0042060;response to stress#GO:0006950;response to wounding#GO:0009611;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tube development#GO:0035295;developmental process#GO:0032502;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000008558.1|UniProtKB=W5MPW8 W5MPW8 PTHR11679:SF3 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45 vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000015393.1|UniProtKB=W5NE81 W5NE81 PTHR13710:SF162 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q1 DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950 chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008306.1|UniProtKB=W5MNY2 W5MNY2 PTHR24381:SF474 ZINC FINGER PROTEIN SI:CH1073-224N8.1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000013196.1|UniProtKB=W5N6J7 W5N6J7 PTHR10921:SF0 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;protein polymerization#GO:0051258;centrosome cycle#GO:0007098;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;centrosome localization#GO:0051642;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128;microtubule-based transport#GO:0099111;nuclear division#GO:0000280;establishment or maintenance of cell polarity#GO:0007163;spindle localization#GO:0051653;cellular localization#GO:0051641;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;establishment of localization in cell#GO:0051649;establishment of mitotic spindle localization#GO:0040001;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;chromosome localization#GO:0050000;organelle transport along microtubule#GO:0072384;cytoskeleton organization#GO:0007010;establishment of vesicle localization#GO:0051650;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;protein-containing complex organization#GO:0043933;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;establishment of cell polarity#GO:0030010;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell motility#GO:0048870;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;organelle localization#GO:0051640;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;localization#GO:0051179;vesicle localization#GO:0051648;establishment of spindle localization#GO:0051293;microtubule polymerization or depolymerization#GO:0031109;biological regulation#GO:0065007;cell migration#GO:0016477;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;regulation of cell projection organization#GO:0031344;microtubule polymerization#GO:0046785;vesicle cytoskeletal trafficking#GO:0099518;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;establishment of mitotic spindle orientation#GO:0000132;regulation of plasma membrane bounded cell projection organization#GO:0120035 microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;kinetochore#GO:0000776;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000005293.1|UniProtKB=W5MDD1 W5MDD1 PTHR45725:SF3 FORMIN HOMOLOGY 2 FAMILY MEMBER DELPHILIN LEPOC|Ensembl=ENSLOCG00000003192.1|UniProtKB=W5M5W0 W5M5W0 PTHR22739:SF20 STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED ACTIN-BINDING RHO-ACTIVATING PROTEIN regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of Rho protein signal transduction#GO:0035023;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016;contractile muscle fiber#GO:0043292;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 LEPOC|Ensembl=ENSLOCG00000001161.1|UniProtKB=W5LYV0 W5LYV0 PTHR11681:SF5 NEUROPHYSIN ISOTOCIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;neuropeptide hormone activity#GO:0005184 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708 peptide hormone#PC00179;neuropeptide#PC00162 Opioid prodynorphin pathway#P05916>prepropressophysin#G06048;Vasopressin synthesis#P04395>Pro-Neurophysin#P04591;Opioid prodynorphin pathway#P05916>provasopressin#P05999;Vasopressin synthesis#P04395>Vasopressin#P04590;Opioid prodynorphin pathway#P05916>vasopressin#P06000;Opioid prodynorphin pathway#P05916>prepropressophysin#G06050;Vasopressin synthesis#P04395>Glycopeptide#P04593;Vasopressin synthesis#P04395>Signal Peptide#P04597;Vasopressin synthesis#P04395>Pro-Vasopressin#P04598;Vasopressin synthesis#P04395>Neurophysin#P04594;Vasopressin synthesis#P04395>Pro2-Vasopressin#P04595 LEPOC|Ensembl=ENSLOCG00000003291.1|UniProtKB=W5M684 W5M684 PTHR12751:SF7 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 3 protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000001599.1|UniProtKB=W5M0F6 W5M0F6 PTHR47735:SF4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 2 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215 cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 voltage-gated ion channel#PC00241;transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>K+ channel#P01070 LEPOC|Ensembl=ENSLOCG00000008753.1|UniProtKB=W5MQK1 W5MQK1 PTHR11596:SF90 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 developmental process#GO:0032502;biomineral tissue development#GO:0031214;bone mineralization#GO:0030282;animal gross anatomical part developmental process#GO:0160108;animal organ development#GO:0048513;anatomical structure development#GO:0048856;tissue development#GO:0009888;multicellular organismal process#GO:0032501;ossification#GO:0001503 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002236.1|UniProtKB=W5M2J8 W5M2J8 PTHR12290:SF13 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 2 trans-synaptic signaling#GO:0099537;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192 endomembrane system#GO:0012505;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;membrane#GO:0016020;neuron projection#GO:0043005;cell junction#GO:0030054;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;synapse#GO:0045202;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;dendrite#GO:0030425;dendritic tree#GO:0097447;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010238.1|UniProtKB=W5MVX7 W5MVX7 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237;reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000001489.1|UniProtKB=W5LZZ1 W5LZZ1 PTHR16047:SF7 RFWD3 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RFWD3 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000002944.1|UniProtKB=W5M514 W5M514 PTHR13344:SF0 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004545.1|UniProtKB=W5MAN7 W5MAN7 PTHR10290:SF5 DNA TOPOISOMERASE I DNA TOPOISOMERASE 1 catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle process#GO:0022402;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009;DNA topoisomerase#PC00017 DNA replication#P00017>DNA Topisomerase#P00536;DNA replication#P00017>Top#P00530 LEPOC|Ensembl=ENSLOCG00000005403.1|UniProtKB=W5MDR6 W5MDR6 PTHR46099:SF3 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ENDOTHELIN RECEPTOR TYPE B molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;pigmentation#GO:0043473;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;developmental pigmentation#GO:0048066;cellular process#GO:0009987;system process#GO:0003008;regulation of anatomical structure size#GO:0090066 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 Endothelin signaling pathway#P00019>ET-RA/B#P00580 LEPOC|Ensembl=ENSLOCG00000014662.1|UniProtKB=W5NBN6 W5NBN6 PTHR28631:SF1 UPF0692 PROTEIN C19ORF54 ACTIN MATURATION PROTEASE aminopeptidase activity#GO:0004177;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000006665.1|UniProtKB=W5MI76 W5MI76 PTHR22573:SF60 PHOSPHOHEXOMUTASE FAMILY MEMBER PHOSPHOGLUCOMUTASE-1 intramolecular phosphotransferase activity#GO:0016868;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 mutase#PC00160;metabolite interconversion enzyme#PC00262;isomerase#PC00135 LEPOC|Ensembl=ENSLOCG00000004297.1|UniProtKB=W5M9S5 W5M9S5 PTHR24006:SF961 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843 regulation of autophagy#GO:0010506;cellular response to stimulus#GO:0051716;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of protein stability#GO:0031647;biological regulation#GO:0065007;DNA damage response#GO:0006974;regulation of catabolic process#GO:0009894 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014017.1|UniProtKB=W5N9H0 W5N9H0 PTHR33667:SF7 SI:DKEY-57N24.6 CILIA AND FLAGELLA ASSOCIATED PROTEIN 92 LEPOC|Ensembl=ENSLOCG00000002705.1|UniProtKB=W5M468 W5M468 PTHR11214:SF23 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;biosynthetic process#GO:0009058;aminoglycan biosynthetic process#GO:0006023;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000017400.1|UniProtKB=W5NLJ6 W5NLJ6 PTHR26451:SF928 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G PROTEIN-COUPLED RECEPTOR 148-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006166.1|UniProtKB=W5MGD8 W5MGD8 KATNB1 PTHR19845:SF0 KATANIN P80 SUBUNIT KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1 cellular component organization#GO:0016043;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule depolymerization#GO:0007019;protein depolymerization#GO:0051261;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435 microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016510.1|UniProtKB=W5NID4 W5NID4 PTHR10796:SF15 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 4 cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007322.1|UniProtKB=W5MKF9 W5MKF9 PTHR12320:SF98 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE PTC7 HOMOLOG regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000016001.1|UniProtKB=W5NGE6 W5NGE6 PTHR14069:SF0 FILENSIN FILENSIN structural molecule activity#GO:0005198 visual system development#GO:0150063;cell development#GO:0048468;cell differentiation#GO:0030154;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;cellular process#GO:0009987;sensory system development#GO:0048880;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular developmental process#GO:0048869 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000010055.1|UniProtKB=W5MVA0 W5MVA0 PTHR24020:SF89 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXI) CHAIN-RELATED external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000001712.1|UniProtKB=W5M0T8 W5M0T8 PTHR10890:SF33 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000016357.1|UniProtKB=W5NHT8 W5NHT8 PTHR10983:SF2 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED ACYL-COA:LYSOPHOSPHATIDYLGLYCEROL ACYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000003260.1|UniProtKB=W5M670 W5M670 PTHR22741:SF11 P140CAP/SNIP-RELATED SICKLE TAIL PROTEIN HOMOLOG cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000008126.1|UniProtKB=W5MNA7 W5MNA7 PTHR47980:SF17 LD44762P RAS-RELATED PROTEIN RAB-3D protein binding#GO:0005515;binding#GO:0005488;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092 secretion by cell#GO:0032940;exocytosis#GO:0006887;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;exocytic vesicle#GO:0070382;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000000362.1|UniProtKB=W5LW87 W5LW87 PTHR11040:SF221 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP3 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000000701.1|UniProtKB=W5LXB9 W5LXB9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009468.1|UniProtKB=W5MT62 W5MT62 PTHR11073:SF16 CALRETICULIN AND CALNEXIN CALRETICULIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;gene expression#GO:0010467;protein maturation#GO:0051604;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein folding#GO:0006457;response to stimulus#GO:0050896;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009046.1|UniProtKB=W5MRM1 W5MRM1 PTHR46010:SF1 PROTEIN IWS1 HOMOLOG PROTEIN IWS1 HOMOLOG transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;localization#GO:0051179;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000013766.1|UniProtKB=W5N8N4 W5N8N4 PTHR18945:SF893 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT BETA postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 response to chemical#GO:0042221;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;response to stimulus#GO:0050896;signaling#GO:0023052;skeletal muscle contraction#GO:0003009;regulation of biological process#GO:0050789;muscle system process#GO:0003012;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;nervous system process#GO:0050877;response to oxygen-containing compound#GO:1901700;cellular response to nitrogen compound#GO:1901699;multicellular organismal process#GO:0032501;acetylcholine receptor signaling pathway#GO:0095500;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;establishment of localization#GO:0051234;system process#GO:0003008;transport#GO:0006810;muscle contraction#GO:0006936;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;trans-synaptic signaling#GO:0099537;neuromuscular process#GO:0050905 transporter complex#GO:1990351;cell junction#GO:0030054;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000016433.1|UniProtKB=W5NI38 W5NI38 PTHR11506:SF45 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 5 establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of protein localization#GO:0045184 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000017544.1|UniProtKB=W5NLZ0 W5NLZ0 PTHR11829:SF361 FORKHEAD BOX PROTEIN FORKHEAD BOX D2 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000011887.1|UniProtKB=W5N1W4 W5N1W4 PTHR46062:SF3 STEROL REGULATORY ELEMENT-BINDING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of localization#GO:0032879;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000004986.1|UniProtKB=W5MC93 W5MC93 PTHR13084:SF2 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 3 regulation of biological process#GO:0050789;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of transport#GO:0051049 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008439.1|UniProtKB=W5MPF3 W5MPF3 PTHR14856:SF10 PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN SOLUTE CARRIER FAMILY 66 MEMBER 2 localization#GO:0051179;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endosomal transport#GO:0016197;regulation of membrane lipid distribution#GO:0097035;intracellular transport#GO:0046907;transport#GO:0006810;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;cytoplasmic vesicle membrane#GO:0030659 LEPOC|Ensembl=ENSLOCG00000017842.1|UniProtKB=W5NMT6 W5NMT6 PTHR11711:SF119 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4C ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 endocytic recycling#GO:0032456;localization within membrane#GO:0051668;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000002348.1|UniProtKB=W5M2Z9 W5M2Z9 PTHR35083:SF3 RGD1565685 PROTEIN SI:CH211-91P5.3 LEPOC|Ensembl=ENSLOCG00000018049.1|UniProtKB=W5NNE1 W5NNE1 PTHR24231:SF48 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011003.1|UniProtKB=W5MYP8 W5MYP8 PTHR13794:SF58 ENOLASE SUPERFAMILY, MANDELATE RACEMASE MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 epimerase/racemase#PC00096 LEPOC|Ensembl=ENSLOCG00000010271.1|UniProtKB=W5MW18 W5MW18 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011596.1|UniProtKB=W5N0V4 W5N0V4 PTHR10953:SF9 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 5 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003664.1|UniProtKB=W5M7L4 W5M7L4 PTHR12156:SF23 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 1 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;basal part of cell#GO:0045178 LEPOC|Ensembl=ENSLOCG00000008850.1|UniProtKB=W5MQW8 W5MQW8 PTHR46526:SF1 CHORDIN CHORDIN binding#GO:0005488;protein binding#GO:0005515;cytokine binding#GO:0019955 multicellular organism development#GO:0007275;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regionalization#GO:0003002;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of BMP signaling pathway#GO:0030510;anatomical structure development#GO:0048856;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;pattern specification process#GO:0007389;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;dorsal/ventral pattern formation#GO:0009953;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DPP signaling pathway#P06213>SOG#P06293;DPP-SCW signaling pathway#P06212>SOG#P06266;BMP/activin signaling pathway-drosophila#P06211>SOG#P06252;SCW signaling pathway#P06216>SOG#P06335 LEPOC|Ensembl=ENSLOCG00000017189.1|UniProtKB=W5NKT5 W5NKT5 PTHR11537:SF39 VOLTAGE-GATED POTASSIUM CHANNEL DELAYED-RECTIFIER POTASSIUM CHANNEL REGULATORY SUBUNIT KCNS3 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459 metal ion transport#GO:0030001;action potential#GO:0001508;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000013948.1|UniProtKB=W5N985 W5N985 PTHR24173:SF78 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG B enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000404.1|UniProtKB=W5LWD9 W5LWD9 PTHR43570:SF7 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 metabolic process#GO:0008152;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000010811.1|UniProtKB=W5MXZ3 W5MXZ3 PTHR48083:SF6 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE 6 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000015755.1|UniProtKB=W5NFI7 W5NFI7 PTHR12673:SF12 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 6 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000014368.1|UniProtKB=W5NAR8 W5NAR8 PTHR24023:SF1029 COLLAGEN ALPHA COLLAGEN ALPHA-5(IV) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000012672.1|UniProtKB=W5N4N9 W5N4N9 PTHR10928:SF2 SUPPRESSOR OF FUSED SUPPRESSOR OF FUSED HOMOLOG protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 Hedgehog signaling pathway#P00025>Su(fu)#P00699 LEPOC|Ensembl=ENSLOCG00000004540.1|UniProtKB=W5MAM5 W5MAM5 PTHR43655:SF8 ATP-DEPENDENT PROTEASE MITOCHONDRIAL INNER MEMBRANE M-AAA PROTEASE COMPONENT PARAPLEGIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000011005.1|UniProtKB=W5MYP3 W5MYP3 PTHR12972:SF0 DOWNSTREAM NEIGHBOR OF SON PROTEIN DOWNSTREAM NEIGHBOR OF SON macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;nucleobase-containing compound metabolic process#GO:0006139;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;cell cycle process#GO:0022402 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000014834.1|UniProtKB=W5NCA5 W5NCA5 PTHR45791:SF5 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 2 small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;magnesium ion binding#GO:0000287;cation binding#GO:0043169 homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;monoatomic ion homeostasis#GO:0050801;calcium ion homeostasis#GO:0055074 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;neuron projection#GO:0043005;cell periphery#GO:0071944;membraneless organelle#GO:0043228;stereocilium#GO:0032420;cytoskeleton#GO:0005856 Ras Pathway#P04393>Rac#P04559 LEPOC|Ensembl=ENSLOCG00000010862.1|UniProtKB=W5MY52 W5MY52 PTHR22807:SF34 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(72)-C(5))-METHYLTRANSFERASE NSUN6 catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;tRNA methyltransferase activity#GO:0008175;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a rRNA#GO:0140102;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 methylation#GO:0032259;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;tRNA modification#GO:0006400;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;rRNA methylation#GO:0031167;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;rRNA base methylation#GO:0070475;cellular process#GO:0009987 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000016244.1|UniProtKB=W5NHC6 W5NHC6 PTHR16266:SF4 WD REPEAT DOMAIN 9 PH-INTERACTING PROTEIN regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000001246.1|UniProtKB=W5LZ56 W5LZ56 PTHR23330:SF9 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED PROLINE-RICH PROTEIN 11 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000017404.1|UniProtKB=W5NLK0 W5NLK0 PTHR15573:SF0 G-PROTEIN COUPLED RECEPTOR 160-RELATED G PROTEIN-COUPLED RECEPTOR 160-RELATED cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012876.1|UniProtKB=W5N5E5 W5N5E5 PTHR24027:SF84 CADHERIN-23 CADHERIN-20 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell adhesion#GO:0007155;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell motility#GO:0048870;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular component assembly#GO:0022607;cell migration#GO:0016477 adherens junction#GO:0005912;anchoring junction#GO:0070161;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000000265.1|UniProtKB=W5LVY3 W5LVY3 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000012517.1|UniProtKB=W5N456 W5N456 PTHR23196:SF43 PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN PAX-INTERACTING PROTEIN 1 cellular response to stress#GO:0033554;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893 histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000010295.1|UniProtKB=W5MW55 W5MW55 PTHR10730:SF8 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN GALACTOSYLTRANSFERASE 2 galactosyltransferase activity#GO:0008378;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010312.1|UniProtKB=W5MW80 W5MW80 PTHR12120:SF9 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER EDAR transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000000554.1|UniProtKB=W5LWV4 W5LWV4 PTHR23277:SF109 NECTIN-RELATED POLIOVIRUS RECEPTOR protein binding#GO:0005515;virus receptor activity#GO:0001618;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;leukocyte mediated cytotoxicity#GO:0001909;natural killer cell mediated immunity#GO:0002228;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune system process#GO:0002376;cell adhesion#GO:0007155;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;innate immune response#GO:0045087;natural killer cell mediated cytotoxicity#GO:0042267;response to external stimulus#GO:0009605;defense response#GO:0006952;cell killing#GO:0001906;immune effector process#GO:0002252 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000013757.1|UniProtKB=W5N8K7 W5N8K7 PTHR18945:SF579 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT THETA ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;channel activity#GO:0015267;chloride channel activity#GO:0005254;neurotransmitter receptor activity#GO:0030594;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 transmembrane transport#GO:0055085;localization#GO:0051179;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987 cell junction#GO:0030054;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000011791.1|UniProtKB=W5N1I4 W5N1I4 PTHR24366:SF57 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005333.1|UniProtKB=W5MDG8 W5MDG8 PTHR10845:SF145 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 19 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 negative regulation of cell communication#GO:0010648;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519 cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000007101.1|UniProtKB=W5MJN9 W5MJN9 PTHR47300:SF1 PROTEIN KASH5 PROTEIN KASH5 protein-containing complex binding#GO:0044877;binding#GO:0005488 actin filament organization#GO:0007015;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;spindle organization#GO:0007051;meiotic nuclear division#GO:0140013;reproductive process#GO:0022414;actin cytoskeleton organization#GO:0030036;telomere localization#GO:0034397;cell cycle#GO:0007049;supramolecular fiber organization#GO:0097435;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;sexual reproduction#GO:0019953;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;meiosis I cell cycle process#GO:0061982;organelle localization#GO:0051640;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;homologous chromosome pairing at meiosis#GO:0007129;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;cell cycle process#GO:0022402;meiosis I#GO:0007127;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;spindle localization#GO:0051653;nuclear division#GO:0000280 intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;nucleus#GO:0005634;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;nuclear chromosome#GO:0000228;intracellular organelle lumen#GO:0070013;outer membrane#GO:0019867;intracellular organelle#GO:0043229;organelle lumen#GO:0043233;spindle pole#GO:0000922;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;synaptonemal complex#GO:0000795;bounding membrane of organelle#GO:0098588;nuclear membrane#GO:0031965;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;synaptonemal structure#GO:0099086;nuclear envelope#GO:0005635;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000009008.1|UniProtKB=W5MRG5 W5MRG5 PTHR11003:SF57 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 13 outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014360.1|UniProtKB=W5NAM3 W5NAM3 PTHR24241:SF69 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GONADOTROPIN-RELEASING HORMONE II RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000007200.1|UniProtKB=W5MK11 W5MK11 PTHR13742:SF8 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-LIKE PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;developmental process#GO:0032502;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle#GO:0045786;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990 transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005654.1|UniProtKB=W5MEL8 W5MEL8 PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN SENTAN calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000003543.1|UniProtKB=W5M740 W5M740 PTHR24184:SF6 SI:CH211-189E2.2 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 3 cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000013319.1|UniProtKB=W5N710 W5N710 PTHR18929:SF210 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A4 protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;cellular response to stress#GO:0033554;protein maturation#GO:0051604;gene expression#GO:0010467;response to stimulus#GO:0050896;protein folding#GO:0006457;biosynthetic process#GO:0009058;response to stress#GO:0006950;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell surface#GO:0009986;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016166.1|UniProtKB=W5NH12 W5NH12 PTHR11662:SF432 SOLUTE CARRIER FAMILY 17 SIALIN carbohydrate derivative transmembrane transporter activity#GO:1901505;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179 lytic vacuole#GO:0000323;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;apical plasma membrane#GO:0016324;lysosome#GO:0005764 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000008738.1|UniProtKB=W5MQH4 W5MQH4 PTHR46096:SF1 PERFORIN-1 PERFORIN 1.5-RELATED passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;leukocyte activation#GO:0045321;defense response to virus#GO:0051607;leukocyte mediated cytotoxicity#GO:0001909;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;response to virus#GO:0009615;T cell mediated immunity#GO:0002456;cell activation#GO:0001775;cell recognition#GO:0008037;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to other organism#GO:0051707;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;immune response#GO:0006955;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;cell-cell recognition#GO:0009988;immune effector process#GO:0002252;cell killing#GO:0001906 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017119.1|UniProtKB=W5NKJ5 W5NKJ5 PTHR10903:SF206 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017735.1|UniProtKB=W5NMI0 W5NMI0 PTHR21255:SF71 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN TCTEX1 DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 organelle#GO:0043226;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000006502.1|UniProtKB=W5MHK2 W5MHK2 PTHR45805:SF7 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-BETA-LIKE transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000006185.1|UniProtKB=W5MGG5 W5MGG5 PTHR42908:SF29 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR 2A.1-RELATED pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000003612.1|UniProtKB=W5M7C1 W5M7C1 PTHR37680:SF1 C130050O18RIK PROTEIN C130050O18RIK PROTEIN LEPOC|Ensembl=ENSLOCG00000016752.1|UniProtKB=W5NJ95 W5NJ95 PTHR22603:SF35 CHOLINE/ETHANOALAMINE KINASE CHOLINE_ETHANOLAMINE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000017085.1|UniProtKB=W5NKF4 W5NKF4 PTHR45652:SF11 GLIAL FIBRILLARY ACIDIC PROTEIN NOTOCHORD GRANULAR SURFACE structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012837.1|UniProtKB=W5N590 W5N590 PTHR48484:SF2 PRO-INTERLEUKIN-16 PRO-INTERLEUKIN-16 protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 Interleukin signaling pathway#P00036>Interleukin#P00970 LEPOC|Ensembl=ENSLOCG00000010981.1|UniProtKB=W5MYL5 W5MYL5 PTHR45632:SF9 LD33804P KELCH-LIKE PROTEIN 9 ISOFORM X1 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 protein metabolic process#GO:0019538;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell cycle#GO:0051726;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cellular process#GO:0009987 catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003057.1|UniProtKB=W5M5K3 W5M5K3 PTHR22730:SF3 PROMININ PROM PROTEIN PROMININ-1 nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;retina development in camera-type eye#GO:0060041;multicellular organismal process#GO:0032501;cellular process#GO:0009987;sensory system development#GO:0048880;camera-type eye morphogenesis#GO:0048593;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;sensory organ development#GO:0007423;visual system development#GO:0150063;cell differentiation#GO:0030154;cell projection organization#GO:0030030;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108 microvillus#GO:0005902;actin-based cell projection#GO:0098858;vesicle#GO:0031982;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;plasma membrane region#GO:0098590;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000009291.1|UniProtKB=W5MSI3 W5MSI3 PTHR23069:SF4 AAA DOMAIN-CONTAINING ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2 ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;histone binding#GO:0042393;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682 nucleic acid biosynthetic process#GO:0141187;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;DNA-templated transcription initiation#GO:0006352;chromatin remodeling#GO:0006338;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;transcription initiation-coupled chromatin remodeling#GO:0045815;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase II promoter#GO:0006367;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biosynthetic process#GO:0009891;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;protein-containing complex disassembly#GO:0032984;DNA-templated transcription#GO:0006351;transcription by RNA polymerase II#GO:0006366;nucleosome organization#GO:0034728;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;chromatin organization#GO:0006325;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000002603.1|UniProtKB=W5M3U9 W5M3U9 PTHR25480:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 73 C-MAF-INDUCING PROTEIN intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytosol#GO:0005829;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000010580.1|UniProtKB=W5MX50 W5MX50 PTHR15600:SF43 SACSIN HEPN DOMAIN-CONTAINING PROTEIN Hsp70 protein binding#GO:0030544;protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 LEPOC|Ensembl=ENSLOCG00000004853.1|UniProtKB=W5MBS5 W5MBS5 BRDT PTHR22880:SF247 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN TESTIS-SPECIFIC PROTEIN chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017993.1|UniProtKB=W5NN85 W5NN85 PTHR20855:SF22 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR BETA molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;lipid binding#GO:0008289;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;steroid binding#GO:0005496;signaling receptor activity#GO:0038023 response to steroid hormone#GO:0048545;response to hormone#GO:0009725;response to endogenous stimulus#GO:0009719;response to lipid#GO:0033993;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004184.1|UniProtKB=W5M9F7 W5M9F7 PIF1 PTHR23274:SF11 DNA HELICASE-RELATED ATP-DEPENDENT DNA HELICASE PIF1 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 DNA helicase#PC00011 LEPOC|Ensembl=ENSLOCG00000013578.1|UniProtKB=W5N7Y3 W5N7Y3 PTHR48112:SF3 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B2 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000014609.1|UniProtKB=W5NBH1 W5NBH1 PTHR22237:SF0 APC MEMBRANE RECRUITMENT PROTEIN 2-RELATED APC MEMBRANE RECRUITMENT PROTEIN 1 protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000224.1|UniProtKB=W5LVU2 W5LVU2 PTHR11003:SF30 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 4 potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003829.1|UniProtKB=W5M864 W5M864 PTHR21292:SF12 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;secretion by cell#GO:0032940;exocytosis#GO:0006887;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;exocyst#GO:0000145;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008585.1|UniProtKB=W5MPX7 W5MPX7 PTHR11653:SF12 PARVALBUMIN ALPHA PARVALBUMIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000008262.1|UniProtKB=W5MNT0 W5MNT0 PTHR48012:SF14 STERILE20-LIKE KINASE, ISOFORM B-RELATED STE20_SPS1-RELATED PROLINE-ALANINE-RICH PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;regulation of chemotaxis#GO:0050920;response to abiotic stimulus#GO:0009628;cellular response to chemical stress#GO:0062197;positive regulation of response to external stimulus#GO:0032103;cellular response to abiotic stimulus#GO:0071214;response to chemical#GO:0042221;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of chemotaxis#GO:0050921;regulation of lymphocyte migration#GO:2000401;cellular response to osmotic stress#GO:0071470;hyperosmotic response#GO:0006972;regulation of leukocyte migration#GO:0002685;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;positive regulation of locomotion#GO:0040017;response to osmotic stress#GO:0006970;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001641.1|UniProtKB=W5M0I9 W5M0I9 PTHR15672:SF12 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN R3H DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000012121.1|UniProtKB=W5N2Q4 W5N2Q4 PTHR48024:SF71 GEO13361P1-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A0 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;positive regulation of biosynthetic process#GO:0009891;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004591.1|UniProtKB=W5MAT8 W5MAT8 PTHR12191:SF17 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP5 monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007325.1|UniProtKB=W5MKG3 W5MKG3 PTHR22950:SF190 AMINO ACID TRANSPORTER NEUTRAL AMINO ACID UNIPORTER 4 neutral L-amino acid transmembrane transporter activity#GO:0015175;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;alanine transport#GO:0032328;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;localization#GO:0051179 intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 secondary carrier transporter#PC00258;amino acid transporter#PC00046 LEPOC|Ensembl=ENSLOCG00000015381.1|UniProtKB=W5NE68 W5NE68 PTHR11471:SF55 TUMOR NECROSIS FACTOR FAMILY MEMBER DEATH LIGAND 3 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016710.1|UniProtKB=W5NJ36 W5NJ36 PTHR11800:SF13 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1 catalytic activity, acting on RNA#GO:0140098;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;RNA polymerase III complex#GO:0005666;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000018225.1|UniProtKB=W5NNW7 W5NNW7 PTHR24381:SF436 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 768 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000000512.1|UniProtKB=W5LWQ7 W5LWQ7 PTHR47980:SF23 LD44762P SMALL MONOMERIC GTPASE exocytosis#GO:0006887;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;localization within membrane#GO:0051668;export from cell#GO:0140352;endocytic recycling#GO:0032456 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037 TGF-beta signaling pathway#P00052>Ras-GTP#P01280;TGF-beta signaling pathway#P00052>Ras-GDP#P01291 LEPOC|Ensembl=ENSLOCG00000010066.1|UniProtKB=W5MVA9 W5MVA9 PTHR18945:SF28 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-2 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;chloride transport#GO:0006821 synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000018019.1|UniProtKB=W5NNB1 W5NNB1 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 14A ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013963.1|UniProtKB=W5N9A5 W5N9A5 PTHR46149:SF2 MIP08469P GTP-BINDING PROTEIN RHES binding#GO:0005488;protein binding#GO:0005515 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000016605.1|UniProtKB=W5NIQ0 W5NIQ0 PTHR45767:SF11 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O3B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>FKHR#P00898 LEPOC|Ensembl=ENSLOCG00000002259.1|UniProtKB=W5M2M8 W5M2M8 PTHR12929:SF4 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;nitrogen compound transport#GO:0071705;vitamin transport#GO:0051180;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009146.1|UniProtKB=W5MRZ3 W5MRZ3 PTHR42904:SF6 NUDIX HYDROLASE, NUDC SUBFAMILY NAD-CAPPED RNA HYDROLASE NUDT12 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pyridine nucleotide catabolic process#GO:0019364;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010586.1|UniProtKB=W5MX61 W5MX61 PTHR11267:SF114 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX19 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 heart development#GO:0007507;embryo development#GO:0009790;cellular process#GO:0009987;animal organ development#GO:0048513;mesoderm development#GO:0007498;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anatomical structure formation involved in morphogenesis#GO:0048646;cell fate specification#GO:0001708;circulatory system development#GO:0072359;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;gastrulation#GO:0007369;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;formation of primary germ layer#GO:0001704;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;mesoderm formation#GO:0001707;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;mesoderm morphogenesis#GO:0048332;heart morphogenesis#GO:0003007;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000017157.1|UniProtKB=W5NKP6 W5NKP6 PTHR23226:SF425 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013393.1|UniProtKB=W5N7B0 W5N7B0 PTHR15075:SF6 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000017536.1|UniProtKB=W5NLY2 W5NLY2 PTHR31224:SF2 UNC119-BINDING PROTEIN C5ORF30 MACROPHAGE IMMUNOMETABOLISM REGULATOR regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;regulation of multicellular organismal process#GO:0051239;regulation of locomotion#GO:0040012;negative regulation of cell motility#GO:2000146;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of cell migration#GO:0030334 LEPOC|Ensembl=ENSLOCG00000005092.1|UniProtKB=W5MCM4 W5MCM4 PTHR12002:SF56 CLAUDIN CLAUDIN-16 transporter activity#GO:0005215;paracellular tight junction channel activity#GO:0160187 localization#GO:0051179;paracellular transport#GO:0160184;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;transport#GO:0006810;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043 apical junction complex#GO:0043296;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000001123.1|UniProtKB=W5LZ27 W5LZ27 PTHR24270:SF20 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1B ISOFORM X1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transfer/carrier protein#PC00219;apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000000119.1|UniProtKB=W5LVI1 W5LVI1 PTHR11771:SF161 LIPOXYGENASE ARACHIDONATE 15-LIPOXYGENASE TYPE B catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 icosanoid metabolic process#GO:0006690;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;arachidonate metabolic process#GO:0019369;lipid oxidation#GO:0034440;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000001770.1|UniProtKB=W5M100 W5M100 PTHR43788:SF10 DNA2/NAM7 HELICASE FAMILY MEMBER 3'-5' EXORIBONUCLEASE HELZ2 macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stress#GO:0006950 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003559.1|UniProtKB=W5M775 W5M775 PTHR46070:SF2 PINSTRIPE, ISOFORM A DENN DOMAIN-CONTAINING PROTEIN 5A molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014254.1|UniProtKB=W5NA89 W5NA89 PTHR15036:SF17 PIKACHURIN-LIKE PROTEIN CHONDROITIN SULFATE PROTEOGLYCAN 4 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011021.1|UniProtKB=W5MYR7 W5MYR7 PTHR46528:SF1 PROTEIN SON PROTEIN SON binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of mRNA processing#GO:0050684;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000004076.1|UniProtKB=W5M916 W5M916 PTHR45857:SF3 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;cell motility#GO:0048870;cell migration#GO:0016477 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000007111.1|UniProtKB=W5MJQ5 W5MJQ5 PTHR21229:SF11 LUNG SEVEN TRANSMEMBRANE RECEPTOR PROTEIN GPR108 regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of cell communication#GO:0010648;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of response to biotic stimulus#GO:0002831;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013476.1|UniProtKB=W5N7K6 W5N7K6 PTHR23194:SF3 PYGOPUS PYGOPUS HOMOLOG 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 cellular response to stimulus#GO:0051716;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;Wnt signaling pathway#GO:0016055;spermatid development#GO:0007286;sexual reproduction#GO:0019953;regulation of RNA metabolic process#GO:0051252;multicellular organismal reproductive process#GO:0048609;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulation of gene expression#GO:0010468;nucleus organization#GO:0006997;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;signaling#GO:0023052;gamete generation#GO:0007276;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell differentiation#GO:0030154;spermatid differentiation#GO:0048515;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 Wnt signaling pathway#P00057>Pygo#P01464 LEPOC|Ensembl=ENSLOCG00000011143.1|UniProtKB=W5MZ79 W5MZ79 PTHR11364:SF27 THIOSULFATE SULFERTANSFERASE SULFURTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;tRNA thio-modification#GO:0034227;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA wobble position uridine thiolation#GO:0002143;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000005551.1|UniProtKB=W5ME94 W5ME94 PTHR48595:SF3 FAMILY NOT NAMED EGF-LIKE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000280.1|UniProtKB=W5LVZ9 W5LVZ9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009742.1|UniProtKB=W5MU41 W5MU41 PTHR34923:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 20 SMALL INTEGRAL MEMBRANE PROTEIN 20 mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003142.1|UniProtKB=W5M5P5 W5M5P5 PTHR28593:SF2 METEORIN-LIKE PROTEIN METEORIN molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;regulation of axonogenesis#GO:0050770;gliogenesis#GO:0042063;positive regulation of cell differentiation#GO:0045597;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of axonogenesis#GO:0050772;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;biological regulation#GO:0065007;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;neurogenesis#GO:0022008;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cellular process#GO:0050794;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;system development#GO:0048731;positive regulation of cell projection organization#GO:0031346 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000007384.1|UniProtKB=W5MKQ0 W5MKQ0 PTHR14202:SF0 60 KDA RIBONUCLEOPROTEIN SSA/RO RNA-BINDING PROTEIN RO60 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012408.1|UniProtKB=W5N3S8 W5N3S8 PTHR15036:SF43 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN 1 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;myelination#GO:0042552;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012366.1|UniProtKB=W5N3L0 W5N3L0 PTHR13149:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS25 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 25 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;cellular localization#GO:0051641;protein transport#GO:0015031;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;localization#GO:0051179;protein localization to vacuole#GO:0072665 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010115.1|UniProtKB=W5MVH8 W5MVH8 PTHR10755:SF0 COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;porphyrin-containing compound biosynthetic process#GO:0006779;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175;metabolite interconversion enzyme#PC00262 Heme biosynthesis#P02746>Coproporphyrinogen Oxidase (oxygen dependent)#P02980 LEPOC|Ensembl=ENSLOCG00000010979.1|UniProtKB=W5MYK8 W5MYK8 PTHR12220:SF13 50S/60S RIBOSOMAL PROTEIN L16 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M structural constituent of ribosome#GO:0003735;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005 LEPOC|Ensembl=ENSLOCG00000003443.1|UniProtKB=W5M6S2 W5M6S2 PTHR48043:SF54 EG:EG0003.4 PROTEIN-RELATED 2-HYDROXYACYLSPHINGOSINE 1-BETA-GALACTOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;glycosphingolipid biosynthetic process#GO:0006688;ceramide metabolic process#GO:0006672;glycolipid biosynthetic process#GO:0009247 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010119.1|UniProtKB=W5MVH9 W5MVH9 PTHR46515:SF1 TATA ELEMENT MODULATORY FACTOR TMF1 TATA ELEMENT MODULATORY FACTOR Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000002907.1|UniProtKB=W5M4V7 W5M4V7 PTHR45640:SF7 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-1 protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to stimulus#GO:0050896;protein folding#GO:0006457;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;response to heat#GO:0009408;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 chaperone#PC00072 p38 MAPK pathway#P05918>HSP27#P06016;VEGF signaling pathway#P00056>HSP27#P01412;CCKR signaling map#P06959>HSP27#P07154;Angiogenesis#P00005>HSP27#P00231 LEPOC|Ensembl=ENSLOCG00000005527.1|UniProtKB=W5ME61 W5ME61 PTHR46160:SF9 ALPHA-TECTORIN-RELATED DENDRITE EXTENSION DEFECTIVE PROTEIN 1-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000011445.1|UniProtKB=W5N0A5 W5N0A5 PTHR11309:SF7 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 4 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;biological regulation#GO:0065007;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>FrzB#P01461 LEPOC|Ensembl=ENSLOCG00000014975.1|UniProtKB=W5NCS7 W5NCS7 PTHR21136:SF179 SNARE PROTEINS VESICLE-ASSOCIATED MEMBRANE PROTEIN 7 SNAP receptor activity#GO:0005484;protein binding#GO:0005515;binding#GO:0005488;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 protein localization to plasma membrane#GO:0072659;Golgi organization#GO:0007030;catabolic process#GO:0009056;Golgi to plasma membrane transport#GO:0006893;microtubule-based movement#GO:0007018;vesicle fusion#GO:0006906;endosome to lysosome transport#GO:0008333;organelle localization#GO:0051640;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;localization#GO:0051179;secretion#GO:0046903;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705;membrane organization#GO:0061024;intracellular transport#GO:0046907;phagocytosis#GO:0006909;vesicle transport along microtubule#GO:0047496;vacuolar transport#GO:0007034;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;endocytosis#GO:0006897;establishment of organelle localization#GO:0051656;export from cell#GO:0140352;Golgi to plasma membrane protein transport#GO:0043001;lysosomal transport#GO:0007041;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;secretion by cell#GO:0032940;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle transport along microtubule#GO:0072384;protein localization to cell periphery#GO:1990778;metabolic process#GO:0008152;membrane invagination#GO:0010324;Golgi vesicle transport#GO:0048193;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;exocytosis#GO:0006887;vesicle organization#GO:0016050;microtubule-based process#GO:0007017 organelle#GO:0043226;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794 SNARE protein#PC00034;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002767.1|UniProtKB=W5M4F8 W5M4F8 PTHR19282:SF44 TETRASPANIN CD82 ANTIGEN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 p53 pathway#P00059>KAI#G04704 LEPOC|Ensembl=ENSLOCG00000005492.1|UniProtKB=W5ME41 W5ME41 PTHR14741:SF32 S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED TRIMETHYLGUANOSINE SYNTHASE RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000007945.1|UniProtKB=W5MMP3 W5MMP3 PTHR13349:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004022.1|UniProtKB=W5M8U5 W5M8U5 PTHR24161:SF118 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010232.1|UniProtKB=W5MVX1 W5MVX1 PTHR14969:SF45 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 dephosphorylation#GO:0016311;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;alcohol metabolic process#GO:0006066;small molecule metabolic process#GO:0044281;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;primary metabolic process#GO:0044238 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013562.1|UniProtKB=W5N7W1 W5N7W1 PTHR22923:SF93 CEREBELLIN-RELATED SI:DKEY-5N18.1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018136.1|UniProtKB=W5NNM8 W5NNM8 PTHR24240:SF72 OPSIN MELANOPSIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to radiation#GO:0071478;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;signal transduction#GO:0007165;regulation of circadian rhythm#GO:0042752;biological regulation#GO:0065007;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009732.1|UniProtKB=W5MU25 W5MU25 PTHR15493:SF1 F-BOX ONLY PROTEIN 5 AND 43 F-BOX ONLY PROTEIN 43 enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;cell cycle#GO:0007049;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;regulation of cellular component organization#GO:0051128;mitotic cell cycle#GO:0000278;mitotic cell cycle phase transition#GO:0044772;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cell cycle G1/S phase transition#GO:0044843;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;negative regulation of cell cycle process#GO:0010948;G1/S transition of mitotic cell cycle#GO:0000082;negative regulation of cellular process#GO:0048523;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of cell cycle#GO:0045786 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011386.1|UniProtKB=W5N039 W5N039 PTHR16231:SF5 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 6 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;response to tumor necrosis factor#GO:0034612;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000011598.1|UniProtKB=W5N0U3 W5N0U3 PTHR16267:SF12 BANK1/PIK3AP1 FAMILY MEMBER PHOSPHOINOSITIDE 3-KINASE ADAPTER PROTEIN 1 phosphatidylinositol 3-kinase binding#GO:0043548;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000014736.1|UniProtKB=W5NBY4 W5NBY4 PTHR19269:SF81 TROPOMYOSIN TROPOMYOSIN 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;system process#GO:0003008;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;muscle contraction#GO:0006936;actin filament-based process#GO:0030029;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;muscle system process#GO:0003012;cellular process#GO:0009987 actin filament#GO:0005884;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000003167.1|UniProtKB=W5M5T3 W5M5T3 PTHR22106:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 78 COILED-COIL DOMAIN-CONTAINING PROTEIN 78 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000012970.1|UniProtKB=W5N5R7 W5N5R7 PTHR13779:SF7 WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER ATPASE WRNIP1 catalytic activity#GO:0003824;enzyme activator activity#GO:0008047;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;molecular function regulator activity#GO:0098772;DNA helicase activity#GO:0003678;ATP-dependent activity#GO:0140657;enzyme regulator activity#GO:0030234;ATP-dependent activity, acting on DNA#GO:0008094;molecular function activator activity#GO:0140677 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated DNA replication#GO:0006261;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;DNA helicase#PC00011 LEPOC|Ensembl=ENSLOCG00000017776.1|UniProtKB=W5NMM1 W5NMM1 PTHR35658:SF1 RCG58666, ISOFORM CRA_A EXOSOMAL POLYCYSTIN-1-INTERACTING PROTEIN organelle localization#GO:0051640;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;mitochondrion localization#GO:0051646;cellular process#GO:0009987;establishment of organelle localization#GO:0051656;export from cell#GO:0140352 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015543.1|UniProtKB=W5NES3 W5NES3 PTHR35578:SF6 PROLINE-RICH TRANSMEMBRANE PROTEIN 4-RELATED PROLINE-RICH TRANSMEMBRANE PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000004931.1|UniProtKB=W5MC30 W5MC30 PTHR47835:SF3 HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG ATP-DEPENDENT DNA HELICASE HFM1-RELATED LEPOC|Ensembl=ENSLOCG00000008199.1|UniProtKB=W5MNJ4 W5MNJ4 PTHR12022:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 7 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000014746.1|UniProtKB=W5NBZ9 W5NBZ9 PTHR46576:SF1 BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000009041.1|UniProtKB=W5MRL9 W5MRL9 PTHR19211:SF15 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2 ATP binding#GO:0005524;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000016633.1|UniProtKB=W5NIT5 W5NIT5 PTHR24240:SF56 OPSIN OPSIN 5-LIKE 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;biological regulation#GO:0065007;signal transduction#GO:0007165;response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;detection of stimulus#GO:0051606;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cellular response to radiation#GO:0071478;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010529.1|UniProtKB=W5MWY8 W5MWY8 PTHR44068:SF1 ZGC:194242 STEROL 4-C-METHYLTRANSFERASE STRM-1 transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000018165.1|UniProtKB=W5NNQ7 W5NNQ7 PTHR11829:SF388 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN CROCODILE transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000006013.1|UniProtKB=W5MFW8 W5MFW8 PTHR11793:SF7 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR E2-ALPHA nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000017849.1|UniProtKB=W5NMU3 W5NMU3 PTHR11767:SF53 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 4 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836 import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000012288.1|UniProtKB=W5N3A9 W5N3A9 PTHR43561:SF3 FAMILY NOT NAMED HYDROXYACYL-COENZYME A DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436 LEPOC|Ensembl=ENSLOCG00000017862.1|UniProtKB=W5NMV6 W5NMV6 PTHR36542:SF7 GIG2-LIKE PROTEIN DRED-RELATED GIG2-LIKE PROTEIN DREO cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007585.1|UniProtKB=W5MLE1 W5MLE1 PTHR21037:SF2 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 53 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000009393.1|UniProtKB=W5MSU7 W5MSU7 PTHR44858:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 6 TETRATRICOPEPTIDE REPEAT DOMAIN 6 LEPOC|Ensembl=ENSLOCG00000006032.1|UniProtKB=W5MFX3 W5MFX3 PTHR15468:SF7 ZNF185 SCIELLIN epidermis development#GO:0008544;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;tissue development#GO:0009888 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010344.1|UniProtKB=W5MWC2 W5MWC2 PTHR24064:SF696 SOLUTE CARRIER FAMILY 22 MEMBER ETT ERGOTHIONEINE TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;quaternary ammonium group transmembrane transporter activity#GO:0015651 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009860.1|UniProtKB=W5MUN0 W5MUN0 PTHR10075:SF43 BASIGIN RELATED CELL ADHESION MOLECULE L1-LIKE A ISOFORM X1 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017234.1|UniProtKB=W5NL07 W5NL07 PTHR14680:SF1 SI:DKEY-126G1.9-RELATED REQUIRED FOR DRUG-INDUCED DEATH PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000000614.1|UniProtKB=W5LX23 W5LX23 PTHR45627:SF6 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 2 lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849 ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841;Beta2 adrenergic receptor signaling pathway#P04378>AC#P04446;Opioid proopiomelanocortin pathway#P05917>AC#P06011;Enkephalin release#P05913>AC#P05978;Nicotine pharmacodynamics pathway#P06587>ADCY2#P06606;5HT1 type receptor mediated signaling pathway#P04373>AC#P04406;Beta1 adrenergic receptor signaling pathway#P04377>AC#P04439;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Histamine H2 receptor mediated signaling pathway#P04386>AC#P04492;5HT4 type receptor mediated signaling pathway#P04376>AC#P04429;Opioid proenkephalin pathway#P05915>AC#P05993;Beta3 adrenergic receptor signaling pathway#P04379>AC#P04450;Opioid prodynorphin pathway#P05916>AC#P06001;Dopamine receptor mediated signaling pathway#P05912>AC#P05947;GABA-B receptor II signaling#P05731>AC#P05760 LEPOC|Ensembl=ENSLOCG00000015138.1|UniProtKB=W5NDC5 W5NDC5 PTHR22774:SF17 CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 3B transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013 cytosolic transport#GO:0016482;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;lipid localization#GO:0010876;membrane organization#GO:0061024;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;endosomal transport#GO:0016197;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000000275.1|UniProtKB=W5LVZ3 W5LVZ3 PTHR45695:SF8 LEUCOKININ RECEPTOR-RELATED NEUROMEDIN-B RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012790.1|UniProtKB=W5N538 W5N538 PTHR46652:SF8 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 23 LEPOC|Ensembl=ENSLOCG00000013787.1|UniProtKB=W5N8P3 W5N8P3 PTHR23036:SF200 CYTOKINE RECEPTOR CYTOKINE RECEPTOR-LIKE FACTOR 3 cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;signaling#GO:0023052;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003301.1|UniProtKB=W5M689 W5M689 PTHR24347:SF354 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 33 ISOFORM X1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000015104.1|UniProtKB=W5ND81 W5ND81 PTHR22939:SF105 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA4 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;positive regulation of apoptotic process#GO:0043065;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cell death#GO:0008219;protein metabolic process#GO:0019538;proteolysis#GO:0006508 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008829.1|UniProtKB=W5MQT4 W5MQT4 PTHR15898:SF13 BIFUNCTIONAL APOPTOSIS REGULATOR GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000004622.1|UniProtKB=W5MAY0 W5MAY0 PTHR11636:SF46 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000001479.1|UniProtKB=W5LZZ4 W5LZZ4 PTHR21222:SF1 MIT DOMAIN-CONTAINING PROTEIN 1 MIT DOMAIN-CONTAINING PROTEIN 1 membrane organization#GO:0061024;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;mitotic cytokinetic process#GO:1902410;cytoskeleton-dependent cytokinesis#GO:0061640;cellular component organization or biogenesis#GO:0071840;cytokinetic process#GO:0032506;cytokinesis#GO:0000910 cellular anatomical structure#GO:0110165;midbody#GO:0030496 LEPOC|Ensembl=ENSLOCG00000007413.1|UniProtKB=W5MKU2 W5MKU2 PTHR11824:SF8 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-3 voltage-gated ion channel#PC00241 5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587 LEPOC|Ensembl=ENSLOCG00000013093.1|UniProtKB=W5N676 W5N676 PTHR10625:SF28 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 5 catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987 nuclear protein-containing complex#GO:0140513;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000005521.1|UniProtKB=W5ME55 W5ME55 PTHR24248:SF140 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR HISTAMINE H3 RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012207.1|UniProtKB=W5N321 W5N321 PTHR22969:SF10 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT EPSILON transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 positive regulation of response to external stimulus#GO:0032103;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;positive regulation of biosynthetic process#GO:0009891;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;regulation of macromolecule metabolic process#GO:0060255;positive regulation of type I interferon production#GO:0032481 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>IKKepsilon#P01372;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871 LEPOC|Ensembl=ENSLOCG00000004117.1|UniProtKB=W5M963 W5M963 PTHR33775:SF2 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;positive regulation of calcium-mediated signaling#GO:0050850;circulatory system process#GO:0003013;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;striated muscle contraction#GO:0006941;regulation of cellular process#GO:0050794;actin-mediated cell contraction#GO:0070252;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;muscle contraction#GO:0006936;positive regulation of intracellular signal transduction#GO:1902533;heart contraction#GO:0060047;system process#GO:0003008;cardiac muscle cell contraction#GO:0086003;actin filament-based movement#GO:0030048;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;heart process#GO:0003015;muscle system process#GO:0003012;regulation of biological process#GO:0050789;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of calcineurin-NFAT signaling cascade#GO:0070884 intracellular organelle#GO:0043229;I band#GO:0031674;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000004733.1|UniProtKB=W5MBE0 W5MBE0 PTHR24103:SF673 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 54 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014328.1|UniProtKB=W5NAJ1 W5NAJ1 PTHR10183:SF434 CALPAIN CALPAIN-9 ISOFORM X1 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012374.1|UniProtKB=W5N3M6 W5N3M6 PTHR18945:SF393 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic ion channel activity#GO:0015276;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;channel activity#GO:0015267;molecular transducer activity#GO:0060089 system development#GO:0048731;cell communication#GO:0007154;localization#GO:0051179;chloride transmembrane transport#GO:1902476;anatomical structure development#GO:0048856;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;synapse assembly#GO:0007416;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;chloride transport#GO:0006821;nervous system development#GO:0007399;cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;cell projection membrane#GO:0031253;dendrite#GO:0030425;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000007002.1|UniProtKB=W5MJB0 W5MJB0 PTHR12245:SF8 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 1 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012596.1|UniProtKB=W5N4F1 W5N4F1 PTHR15283:SF3 GREMLIN 1 GREMLIN-1 molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002797.1|UniProtKB=W5M4I4 W5M4I4 PTHR10300:SF6 CALCIPRESSIN CALCIPRESSIN-3 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015680.1|UniProtKB=W5NF92 W5NF92 PTHR11913:SF54 COFILIN-RELATED CFL1 PROTEIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;protein depolymerization#GO:0051261;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;actin filament depolymerization#GO:0030042 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000007011.1|UniProtKB=W5MJE5 W5MJE5 PTHR12702:SF2 SEC15 EXOCYST COMPLEX COMPONENT 6 secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;exocyst#GO:0000145;cytoplasm#GO:0005737;cell cortex#GO:0005938;cell periphery#GO:0071944 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006119.1|UniProtKB=W5MG86 W5MG86 PTHR11703:SF0 DEOXYHYPUSINE SYNTHASE DEOXYHYPUSINE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 biogenic amine metabolic process#GO:0006576;polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006199.1|UniProtKB=W5MGI2 W5MGI2 PTHR11958:SF22 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 5 active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;solute:monoatomic cation symporter activity#GO:0015294;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;monoatomic cation transmembrane transporter activity#GO:0008324;sodium:dicarboxylate symporter activity#GO:0017153;symporter activity#GO:0015293 carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;L-glutamate import#GO:0051938;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;acidic amino acid transport#GO:0015800 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 LEPOC|Ensembl=ENSLOCG00000013143.1|UniProtKB=W5N6D3 W5N6D3 PTHR10160:SF30 NAD(P) TRANSHYDROGENASE NAD(P) TRANSHYDROGENASE, MITOCHONDRIAL ISOFORM X1 nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000002173.1|UniProtKB=W5M2C0 W5M2C0 PTHR45697:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007754.1|UniProtKB=W5MM09 W5MM09 PTHR14490:SF5 ZINC FINGER, ZZ TYPE PROTEIN KRI1 HOMOLOG maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;90S preribosome#GO:0030686;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012077.1|UniProtKB=W5N2K1 W5N2K1 PTHR19375:SF184 HEAT SHOCK PROTEIN 70KDA STRESS-70 PROTEIN, MITOCHONDRIAL ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;iron-sulfur cluster assembly#GO:0016226;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein refolding#GO:0042026;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208 LEPOC|Ensembl=ENSLOCG00000007559.1|UniProtKB=W5MLB4 W5MLB4 PTHR24056:SF111 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 5 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011617.1|UniProtKB=W5N0W4 W5N0W4 PTHR31516:SF22 STABILIZER OF AXONEMAL MICROTUBULES 2 STABILIZER OF AXONEMAL MICROTUBULES 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;microtubule#GO:0005874;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;cytoplasmic microtubule#GO:0005881;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;supramolecular polymer#GO:0099081;sperm flagellum#GO:0036126;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000015911.1|UniProtKB=W5NG33 W5NG33 PTHR21257:SF59 DELTA(14)-STEROL REDUCTASE DELTA(14)-STEROL REDUCTASE TM7SF2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;secondary alcohol biosynthetic process#GO:1902653;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652 membrane#GO:0016020;organelle inner membrane#GO:0019866;nucleus#GO:0005634;endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;organelle envelope#GO:0031967;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000015621.1|UniProtKB=W5NF19 W5NF19 PTHR10332:SF9 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932 cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016856.1|UniProtKB=W5NJM8 W5NJM8 PTHR23140:SF1 RNA PROCESSING PROTEIN LD23810P SR-RELATED CTD ASSOCIATED FACTOR 8 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011784.1|UniProtKB=W5N1I7 W5N1I7 PTHR44029:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000007506.1|UniProtKB=W5ML50 W5ML50 PTHR43775:SF56 FATTY ACID SYNTHASE FATTY ACID SYNTHASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 LEPOC|Ensembl=ENSLOCG00000002613.1|UniProtKB=W5M3W7 W5M3W7 PTHR22738:SF3 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 6 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001819.1|UniProtKB=W5M148 W5M148 PTHR23050:SF325 CALCIUM BINDING PROTEIN CENTRIN-3 cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000003895.1|UniProtKB=W5M8D9 W5M8D9 PTHR16516:SF5 AGAP007109-PA ZINC FINGER PROTEIN 488 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003693.1|UniProtKB=W5M7M7 W5M7M7 PTHR20426:SF0 RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG 18S RRNA AMINOCARBOXYPROPYLTRANSFERASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a rRNA#GO:0140102 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012211.1|UniProtKB=W5N320 W5N320 PTHR10373:SF32 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7-LIKE 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of carbohydrate metabolic process#GO:0006109;regulation of response to stimulus#GO:0048583;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of signal transduction#GO:0009968;regulation of canonical Wnt signaling pathway#GO:0060828;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;RNA polymerase II transcription regulator complex#GO:0090575 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Angiogenesis#P00005>TCF#P00242;Cadherin signaling pathway#P00012>TCF/LEF#P00465 LEPOC|Ensembl=ENSLOCG00000003251.1|UniProtKB=W5M631 W5M631 PTHR24419:SF18 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE HASPIN histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell cycle#GO:0007049;signaling#GO:0023052;biological regulation#GO:0065007;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013512.1|UniProtKB=W5N7Q5 W5N7Q5 PTHR23413:SF1 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N 60S RIBOSOMAL PROTEIN L32 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000016388.1|UniProtKB=W5NHY1 W5NHY1 PTHR45712:SF32 AGAP008170-PA LUMICAN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002248.1|UniProtKB=W5M2L5 W5M2L5 PTHR24132:SF24 ANKYRIN REPEAT AND SOCS BOX PROTEIN 6 ANKYRIN REPEAT AND SOCS BOX PROTEIN 6 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005738.1|UniProtKB=W5MEX3 W5MEX3 PTHR24085:SF0 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 2 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;nuclear receptor binding#GO:0016922;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837 cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;generation of neurons#GO:0048699;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;cellular response to peptide hormone stimulus#GO:0071375;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;system development#GO:0048731;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010622.1|UniProtKB=W5MXB0 W5MXB0 PTHR13283:SF11 KREV INTERACTION TRAPPED 1-RELATED KREV INTERACTION TRAPPED PROTEIN 1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 regulation of establishment or maintenance of cell polarity#GO:0032878;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of vasculature development#GO:1901342;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;multicellular organism development#GO:0007275;anterior/posterior axis specification#GO:0009948;negative regulation of angiogenesis#GO:0016525;regulation of anatomical structure morphogenesis#GO:0022603;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;regulation of developmental process#GO:0050793;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of angiogenesis#GO:0045765 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009560.1|UniProtKB=W5MTH9 W5MTH9 PTHR45973:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED CENTROSOMAL PROTEIN OF 97 KDA regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cell projection assembly#GO:0060491;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cilium assembly#GO:1902017;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000012054.1|UniProtKB=W5N4F2 W5N4F2 PTHR24068:SF532 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000012827.1|UniProtKB=W5N577 W5N577 PTHR46614:SF1 MORN REPEAT-CONTAINING PROTEIN 4 MORN REPEAT-CONTAINING PROTEIN 4 response to stress#GO:0006950;response to wounding#GO:0009611;response to stimulus#GO:0050896 cell projection#GO:0042995;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004351.1|UniProtKB=W5MA10 W5MA10 PTHR31431:SF1 NUCLEOPORIN NUP188 HOMOLOG NUCLEOPORIN NUP188 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;nuclear export#GO:0051168;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104 nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015236.1|UniProtKB=W5NDP0 W5NDP0 PTHR19970:SF0 RIBOSOMAL PROTEIN L39E LARGE RIBOSOMAL SUBUNIT PROTEIN EL39 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000005246.1|UniProtKB=W5MD62 W5MD62 PTHR13866:SF18 SPARC OSTEONECTIN TESTICAN-2 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;ion binding#GO:0043167;endopeptidase regulator activity#GO:0061135;small molecule binding#GO:0036094;peptidase inhibitor activity#GO:0030414;binding#GO:0005488;peptidase regulator activity#GO:0061134;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cation binding#GO:0043169 regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;regulation of biological process#GO:0050789 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000005090.1|UniProtKB=W5MCM2 W5MCM2 PTHR16322:SF1 PHOSPHOPROTEIN ASSOCIATED WITH GLYCOSPHINGOLIPID-ENRICHED MICRODOMAINS 1 LCK-INTERACTING TRANSMEMBRANE ADAPTER 1 negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cell activation#GO:0050866;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;regulation of T cell activation#GO:0050863;negative regulation of cell adhesion#GO:0007162;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of T cell activation#GO:0050868;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell activation#GO:0050865;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;negative regulation of multicellular organismal process#GO:0051241;regulation of lymphocyte activation#GO:0051249;negative regulation of leukocyte cell-cell adhesion#GO:1903038;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane microdomain#GO:0098857;membrane raft#GO:0045121;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007976.1|UniProtKB=W5MMT2 W5MMT2 PTHR10015:SF213 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000003965.1|UniProtKB=W5M8Q0 W5M8Q0 PTHR12461:SF106 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND ARGINYL-HYDROXYLASE JMJD5 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;protein demethylase activity#GO:0140457;binding#GO:0005488;chromatin binding#GO:0003682;dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009192.1|UniProtKB=W5MS48 W5MS48 PTHR11767:SF3 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 13 monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244 metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000012115.1|UniProtKB=W5N2P8 W5N2P8 PTHR13479:SF40 30S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000013484.1|UniProtKB=W5N7L6 W5N7L6 PTHR10031:SF32 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE LIPID-BINDING PROTEIN primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000018174.1|UniProtKB=W5NNR6 W5NNR6 PTHR24249:SF376 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 4 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003024.1|UniProtKB=W5M5B8 W5M5B8 PTHR12308:SF51 ANOCTAMIN ANOCTAMIN-8 intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128 lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000006724.1|UniProtKB=W5MIC1 W5MIC1 PTHR11036:SF10 SEMAPHORIN SEMAPHORIN-6B molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;axon guidance#GO:0007411;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neuron projection development#GO:0031175 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000014565.1|UniProtKB=W5NBC7 W5NBC7 PTHR11199:SF3 STROMAL ANTIGEN COHESIN SUBUNIT SA-2 chromatin binding#GO:0003682;binding#GO:0005488 chromosome organization#GO:0051276;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000270.1|UniProtKB=W5LVY8 W5LVY8 PTHR14098:SF17 SH2 DOMAIN CONTAINING PROTEIN SI:DKEYP-117B11.1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001101.1|UniProtKB=W5LYN3 W5LYN3 PTHR11685:SF435 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF19B protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004078.1|UniProtKB=W5M912 W5M912 PTHR15119:SF2 SECRETOGRANIN II SECRETOGRANIN-2B LEPOC|Ensembl=ENSLOCG00000017880.1|UniProtKB=W5NMX4 W5NMX4 PTHR11984:SF33 CONNEXIN GAP JUNCTION ALPHA-1 PROTEIN passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;animal organ development#GO:0048513;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological process#GO:0050789;cellular process#GO:0009987;circulatory system development#GO:0072359;heart development#GO:0007507;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell junction#GO:0030054 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000013111.1|UniProtKB=W5N692 W5N692 PTHR10533:SF14 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PEPTIDE YY-RELATED G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;neuropeptide hormone activity#GO:0005184;signaling receptor binding#GO:0005102;binding#GO:0005488;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515 G protein-coupled receptor signaling pathway#GO:0007186;feeding behavior#GO:0007631;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016614.1|UniProtKB=W5NIR3 W5NIR3 PTHR31233:SF3 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D HOMOLOG 1 cytoskeletal protein binding#GO:0008092;cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 positive regulation of endocytosis#GO:0045807;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;organelle organization#GO:0006996;macromolecule localization#GO:0033036;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840;microtubule anchoring#GO:0034453;regulation of transport#GO:0051049;regulation of localization#GO:0032879;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;regulation of endocytosis#GO:0030100;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;regulation of microtubule-based process#GO:0032886;positive regulation of cellular component organization#GO:0051130 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000003766.1|UniProtKB=W5M805 W5M805 PTHR11359:SF2 AMP DEAMINASE AMP DEAMINASE 3 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814 purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside phosphate biosynthetic process#GO:1901293 deaminase#PC00088 Purine metabolism#P02769>5'-AMP Deaminase#P03117 LEPOC|Ensembl=ENSLOCG00000012006.1|UniProtKB=W5N2B4 W5N2B4 PTHR12352:SF3 SECRETED MODULAR CALCIUM-BINDING PROTEIN NIDOGEN-2 cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000005978.1|UniProtKB=W5MFR7 W5MFR7 PTHR12442:SF26 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;microtubule-based transport#GO:0099111;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004518.1|UniProtKB=W5MAL6 W5MAL6 PTHR24006:SF888 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000007195.1|UniProtKB=W5MK02 W5MK02 PTHR20837:SF2 CENTROSOMAL PROTEIN-RELATED PROTEIN CC2D2B organelle assembly#GO:0070925;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;localization#GO:0051179;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000001894.1|UniProtKB=W5M1D8 W5M1D8 PTHR46661:SF3 E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZNRF2 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015098.1|UniProtKB=W5ND72 W5ND72 PTHR13924:SF12 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 1 DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;nuclear receptor binding#GO:0016922;binding#GO:0005488;transcription factor binding#GO:0008134 nuclear migration#GO:0007097;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656;cytoplasmic microtubule organization#GO:0031122;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;supramolecular fiber organization#GO:0097435;system development#GO:0048731;localization#GO:0051179;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;developmental process#GO:0032502;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000011363.1|UniProtKB=W5N016 W5N016 PTHR10663:SF315 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN 4A-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000001649.1|UniProtKB=W5M0J8 W5M0J8 PTHR12120:SF1 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000012784.1|UniProtKB=W5N531 W5N531 PTHR10676:SF339 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN AXONEMAL HEAVY CHAIN 6 protein binding#GO:0005515;microtubule motor activity#GO:0003777;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 microtubule-based movement#GO:0007018;cell motility#GO:0048870;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341 dynein complex#GO:0030286;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000006831.1|UniProtKB=W5MIQ2 W5MIQ2 PTHR10972:SF76 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 6 steroid binding#GO:0005496;cholesterol binding#GO:0015485;lipid binding#GO:0008289;alcohol binding#GO:0043178;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094 cytosol#GO:0005829;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;organelle envelope#GO:0031967;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000011533.1|UniProtKB=W5N0L4 W5N0L4 PTHR12604:SF2 KU AUTOANTIGEN DNA HELICASE DNA REPAIR PROTEIN KU70 telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular response to stress#GO:0033554;telomere organization#GO:0032200;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA helicase#PC00011 LEPOC|Ensembl=ENSLOCG00000011086.1|UniProtKB=W5MZ07 W5MZ07 PTHR15427:SF5 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-2 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;regulation of coagulation#GO:0050818;regulation of hemostasis#GO:1900046;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of developmental process#GO:0051094;regulation of vasculature development#GO:1901342;regulation of response to stress#GO:0080134;regulation of developmental process#GO:0050793;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;regulation of angiogenesis#GO:0045765;regulation of platelet activation#GO:0010543;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;positive regulation of cell-cell adhesion#GO:0022409;regulation of response to wounding#GO:1903034;regulation of anatomical structure morphogenesis#GO:0022603;regulation of wound healing#GO:0061041;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;positive regulation of angiogenesis#GO:0045766;regulation of biological quality#GO:0065008;regulation of platelet aggregation#GO:0090330;positive regulation of coagulation#GO:0050820 supramolecular fiber#GO:0099512;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;protein complex involved in cell adhesion#GO:0098636;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008472.1|UniProtKB=W5MPK8 W5MPK8 PTHR45752:SF80 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEATS AND CALPONIN HOMOLOGY (CH) DOMAIN CONTAINING 4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003685.1|UniProtKB=W5M7N3 W5M7N3 PTHR13155:SF1 A-KINASE ANCHOR PROTEINS A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 intracellular protein localization#GO:0008104;localization#GO:0051179;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014414.1|UniProtKB=W5NAT4 W5NAT4 PTHR17604:SF4 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 VESTIGIAL-LIKE 4 LIKE binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000015053.1|UniProtKB=W5ND16 W5ND16 PTHR11699:SF131 ALDEHYDE DEHYDROGENASE-RELATED MITOCHONDRIAL 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity#GO:0016491 carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000002853.1|UniProtKB=W5M4Q1 W5M4Q1 PTHR46395:SF1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of transport#GO:0051049;regulation of intracellular signal transduction#GO:1902531;regulation of endocytosis#GO:0030100;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 GTPase-activating protein#PC00257;G-protein modulator#PC00022 Integrin signalling pathway#P00034>ASAP1#P00909 LEPOC|Ensembl=ENSLOCG00000012668.1|UniProtKB=W5N4M9 W5N4M9 PTHR10177:SF363 CYCLINS G1_S-SPECIFIC CYCLIN-D3 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;mitotic cell cycle phase transition#GO:0044772;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;transferase complex#GO:1990234;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000001780.1|UniProtKB=W5M108 W5M108 PTHR14392:SF2 NIBAN FAMILY MEMBER PROTEIN NIBAN 2 LEPOC|Ensembl=ENSLOCG00000014925.1|UniProtKB=W5NCM0 W5NCM0 PTHR24279:SF130 CYTOCHROME P450 CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME, MITOCHONDRIAL response to peptide hormone#GO:0043434;biological regulation#GO:0065007;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular response to nitrogen compound#GO:1901699;hormone metabolic process#GO:0042445;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cellular response to peptide hormone stimulus#GO:0071375;hormone biosynthetic process#GO:0042446;response to nitrogen compound#GO:1901698;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;steroid metabolic process#GO:0008202;response to chemical#GO:0042221;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;regulation of hormone levels#GO:0010817;ketone metabolic process#GO:0042180;response to endogenous stimulus#GO:0009719;secondary alcohol metabolic process#GO:1902652;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;response to oxygen-containing compound#GO:1901700;olefinic compound metabolic process#GO:0120254;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000007519.1|UniProtKB=W5ML68 W5ML68 PTHR24012:SF466 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;nucleus#GO:0005634;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003609.1|UniProtKB=W5M7B7 W5M7B7 PTHR15073:SF3 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 2 organelle organization#GO:0006996;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule-based process#GO:0032886;microtubule bundle formation#GO:0001578;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000015761.1|UniProtKB=W5NFJ3 W5NFJ3 PTHR14467:SF0 ARV1 PROTEIN ARV1 glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000017118.1|UniProtKB=W5NKJ2 W5NKJ2 PTHR24343:SF593 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE BRSK2 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell cycle process#GO:0022402;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cell cycle G2/M phase transition#GO:0044839;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;mitotic cell cycle phase transition#GO:0044772;anatomical structure development#GO:0048856;system development#GO:0048731;cell cycle#GO:0007049;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;G2/M transition of mitotic cell cycle#GO:0000086;cell cycle phase transition#GO:0044770;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;mitotic cell cycle process#GO:1903047;neurogenesis#GO:0022008;axon development#GO:0061564;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016604.1|UniProtKB=W5NIP9 W5NIP9 PTHR12169:SF6 ATPASE N2B AFG1-LIKE ATPASE ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000012326.1|UniProtKB=W5N3G9 W5N3G9 PTHR43977:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000001587.1|UniProtKB=W5M0C4 W5M0C4 PTHR13326:SF21 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE PUS7L catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 RNA modification#GO:0009451;metabolic process#GO:0008152;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;pseudouridine synthesis#GO:0001522;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000020971.1|UniProtKB=Q8HQN3 Q8HQN3 PTHR11432:SF23 NADH DEHYDROGENASE SUBUNIT 1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 1 NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000015561.1|UniProtKB=W5NEV4 W5NEV4 PTHR18947:SF30 HOOK PROTEINS GIRDIN protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cytoplasmic microtubule organization#GO:0031122;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;cytoskeleton organization#GO:0007010;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004000.1|UniProtKB=W5M8R3 W5M8R3 PTHR11767:SF100 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 3 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000014730.1|UniProtKB=W5NBX6 W5NBX6 PTHR24419:SF37 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;protein serine/threonine kinase activity#GO:0004674;histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;cellular response to cytokine stimulus#GO:0071345;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;response to lipopolysaccharide#GO:0032496;cell surface receptor signaling pathway#GO:0007166;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to bacterium#GO:0009617;cytokine-mediated signaling pathway#GO:0019221;lipopolysaccharide-mediated signaling pathway#GO:0031663;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;mitotic cell cycle#GO:0000278;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;cellular response to biotic stimulus#GO:0071216;positive regulation of signal transduction#GO:0009967;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;cellular response to molecule of bacterial origin#GO:0071219;response to external stimulus#GO:0009605;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000015582.1|UniProtKB=W5NEX6 W5NEX6 PTHR24166:SF27 ROLLING PEBBLES, ISOFORM B CORTACTIN-BINDING PROTEIN 2 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of cellular component organization#GO:0051128;regulation of synapse structure or activity#GO:0050803;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of synapse organization#GO:0050807 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006997.1|UniProtKB=W5MJA5 W5MJA5 PTHR31400:SF1 GUANYLYL CYCLASE DOMAIN CONTAINING PROTEIN 1 GUCD1 PROTEIN GUCD1 guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000009236.1|UniProtKB=W5MSA2 W5MSA2 PTHR22913:SF7 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 2 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 aminoglycan biosynthetic process#GO:0006023;cellular component organization#GO:0016043;glycosaminoglycan metabolic process#GO:0030203;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;aminoglycan metabolic process#GO:0006022;extracellular structure organization#GO:0043062;polysaccharide biosynthetic process#GO:0000271;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;extracellular matrix assembly#GO:0085029;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;glycosaminoglycan biosynthetic process#GO:0006024;carbohydrate derivative biosynthetic process#GO:1901137 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000004938.1|UniProtKB=W5MC31 W5MC31 PTHR11767:SF19 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 2 voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;transport#GO:0006810;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741 LEPOC|Ensembl=ENSLOCG00000017149.1|UniProtKB=W5NKN4 W5NKN4 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006463.1|UniProtKB=W5MHE9 W5MHE9 PTHR10696:SF33 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED GAMMA-BUTYROBETAINE DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213 carnitine metabolic process#GO:0009437;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008396.1|UniProtKB=W5MP93 W5MP93 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000000558.1|UniProtKB=W5LWV9 W5LWV9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017943.1|UniProtKB=W5NN37 W5NN37 PTHR22752:SF5 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 61 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017650.1|UniProtKB=W5NM96 W5NM96 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003576.1|UniProtKB=W5M784 W5M784 PTHR13832:SF827 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1L catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000003886.1|UniProtKB=W5M8D5 W5M8D5 PTHR46319:SF5 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 9 ISOFORM X1 transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012020.1|UniProtKB=W5N2C2 W5N2C2 PTHR11866:SF14 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN D2 RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological quality#GO:0065008;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;positive regulation of cytosolic calcium ion concentration#GO:0007204;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011160.1|UniProtKB=W5MZA4 W5MZA4 PTHR24083:SF48 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 2 transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 CCKR signaling map#P06959>TAK1#P07170 LEPOC|Ensembl=ENSLOCG00000015045.1|UniProtKB=W5ND07 W5ND07 PTHR46314:SF2 SOLUTE CARRIER FAMILY 25 MEMBER 44 SOLUTE CARRIER FAMILY 25 MEMBER 44 branched-chain amino acid transmembrane transporter activity#GO:0015658;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857 nitrogen compound transport#GO:0071705;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;branched-chain amino acid transport#GO:0015803 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014432.1|UniProtKB=W5NAV5 W5NAV5 PTHR23402:SF28 PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED PYROGLUTAMYL-PEPTIDASE 1 ISOFORM X1 catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000011091.1|UniProtKB=W5MZ15 W5MZ15 PTHR46282:SF1 LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN LEPOC|Ensembl=ENSLOCG00000010930.1|UniProtKB=W5MYG6 W5MYG6 PTHR45929:SF2 JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE SIGNAL TRANSDUCING ADAPTER MOLECULE 1 establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular localization#GO:0051641;protein transport#GO:0015031;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017088.1|UniProtKB=W5NKF9 W5NKF9 PTHR18937:SF147 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1B nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008418.1|UniProtKB=W5MPC9 W5MPC9 PTHR10217:SF466 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED INWARDLY RECTIFYING POTASSIUM CHANNEL KCNH7 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000015879.1|UniProtKB=W5NFZ5 W5NFZ5 PTHR11220:SF24 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 1 heme binding#GO:0020037;binding#GO:0005488;tetrapyrrole binding#GO:0046906 LEPOC|Ensembl=ENSLOCG00000001585.1|UniProtKB=W5M0B1 W5M0B1 PTHR46052:SF3 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;9+0 non-motile cilium#GO:0097731 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Phosducin#P00758 LEPOC|Ensembl=ENSLOCG00000005797.1|UniProtKB=W5MF43 W5MF43 PTHR15427:SF43 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT B PRECURSOR signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;regulation of immune response#GO:0050776;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;humoral immune response#GO:0006959;biological regulation#GO:0065007;adaptive immune response#GO:0002250;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;complement activation#GO:0006956;immune response#GO:0006955;positive regulation of immune system process#GO:0002684 membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;protein-containing complex#GO:0032991;glutamatergic synapse#GO:0098978;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;extracellular protein-containing complex#GO:0140392;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006219.1|UniProtKB=W5MGK0 W5MGK0 PTHR32005:SF3 TRANSMEMBRANE PROTEIN 178B-RELATED SI:CH211-150G13.3-RELATED cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000001134.1|UniProtKB=W5LYT8 W5LYT8 PTHR43655:SF7 ATP-DEPENDENT PROTEASE MITOCHONDRIAL INNER MEMBRANE M-AAA PROTEASE COMPONENT AFG3L1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;peptidase complex#GO:1905368;cytoplasm#GO:0005737 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001438.1|UniProtKB=W5LZU4 W5LZU4 TNC PTHR46708:SF18 TENASCIN TENASCIN C-RELATED regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000002615.1|UniProtKB=W5M3W8 W5M3W8 PTHR11767:SF52 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 4 voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;transport#GO:0006810;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741 LEPOC|Ensembl=ENSLOCG00000016336.1|UniProtKB=W5NHQ8 W5NHQ8 PTHR10812:SF5 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-DELTA transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011413.1|UniProtKB=W5N070 W5N070 PTHR14186:SF19 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;tube development#GO:0035295;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000010373.1|UniProtKB=W5MWH5 W5MWH5 PTHR24222:SF93 ABC TRANSPORTER B FAMILY ABC-TYPE XENOBIOTIC TRANSPORTER primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000000718.1|UniProtKB=W5LXF2 W5LXF2 PTHR46199:SF2 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;intracellular signaling cassette#GO:0141124;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;nuclear division#GO:0000280;cytokinesis#GO:0000910;Rho protein signal transduction#GO:0007266;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;signaling#GO:0023052;mitotic spindle organization#GO:0007052;response to stimulus#GO:0050896;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;organelle assembly#GO:0070925;intracellular signal transduction#GO:0035556;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cell communication#GO:0007154;cell division#GO:0051301;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278 midbody#GO:0030496;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular protein-containing complex#GO:0140535;cleavage furrow#GO:0032154;membraneless organelle#GO:0043228 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000002688.1|UniProtKB=W5M460 W5M460 PTHR46877:SF13 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 5 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714 axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564 dendrite#GO:0030425;dendritic tree#GO:0097447;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007679.1|UniProtKB=W5MLR1 W5MLR1 PTHR13113:SF1 ECSIT EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAY, MITOCHONDRIAL positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of response to stress#GO:0080134;response to other organism#GO:0051707;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;toll-like receptor 4 signaling pathway#GO:0034142;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;activation of innate immune response#GO:0002218;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>ECSIT#P01349 LEPOC|Ensembl=ENSLOCG00000013289.1|UniProtKB=W5N6W3 W5N6W3 PTHR11630:SF93 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM6 DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;DNA damage response#GO:0006974;DNA recombination#GO:0006310;mitotic DNA replication#GO:1902969;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;MCM complex#GO:0042555 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005213.1|UniProtKB=W5MD16 W5MD16 PTHR19842:SF0 G BETA-LIKE PROTEIN GBL TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970;TOR signaling#GO:0031929;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 TOR complex#GO:0038201;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000016123.1|UniProtKB=W5NGW1 W5NGW1 PTHR21568:SF0 TRNA PSEUDOURIDINE SYNTHASE PUS10 TRNA PSEUDOURIDINE SYNTHASE PUS10 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;intramolecular transferase activity#GO:0016866;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;isomerase activity#GO:0016853 pseudouridine synthesis#GO:0001522;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;macromolecule modification#GO:0043412;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;tRNA modification#GO:0006400;negative regulation of metabolic process#GO:0009892;RNA modification#GO:0009451;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;primary miRNA processing#GO:0031053;tRNA processing#GO:0008033 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011326.1|UniProtKB=W5MZV6 W5MZV6 MYPN PTHR13817:SF67 TITIN MYOPALLADIN structural molecule activity#GO:0005198 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927 M band#GO:0031430;intracellular organelle#GO:0043229;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;A band#GO:0031672;contractile muscle fiber#GO:0043292;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005820.1|UniProtKB=W5MF72 W5MF72 PTHR10517:SF19 FOLATE RECEPTOR RETBINDIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;signaling receptor activity#GO:0038023;heterocyclic compound binding#GO:1901363;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;molecular transducer activity#GO:0060089 transport#GO:0006810;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234;vitamin transport#GO:0051180 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000011272.1|UniProtKB=W5MZP9 W5MZP9 PTHR21567:SF90 CLASP TOG ARRAY REGULATOR OF AXONEMAL MICROTUBULES PROTEIN 1 ISOFORM X1 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoplasmic microtubule#GO:0005881;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000012450.1|UniProtKB=W5N3X5 W5N3X5 PTHR11849:SF13 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-3 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000012735.1|UniProtKB=W5N4W0 W5N4W0 PTHR13563:SF19 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG B RNA binding#GO:0003723;tRNA binding#GO:0000049;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA methylation#GO:0001510;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000012003.1|UniProtKB=W5N2A5 W5N2A5 PTHR12360:SF1 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 NF-X1-TYPE ZINC FINGER PROTEIN NFXL1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008179.1|UniProtKB=W5MNG8 W5MNG8 PTHR43313:SF2 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 steroid metabolic process#GO:0008202;lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000008581.1|UniProtKB=W5MPY8 W5MPY8 PTHR45739:SF4 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 2 anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;epithelial structure maintenance#GO:0010669;homeostatic process#GO:0042592;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000565.1|UniProtKB=W5LWW6 W5LWW6 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune system process#GO:0002376;immune effector process#GO:0002252;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013068.1|UniProtKB=W5N636 W5N636 PTHR16717:SF7 CYTOCHROME C OXIDASE POLYPEPTIDE VIII COX8 DOMAIN-CONTAINING PROTEIN respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transporter complex#GO:1990351;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495 oxidase#PC00175;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006556.1|UniProtKB=W5MHR0 W5MHR0 PTHR23320:SF128 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A-LIKE transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005682.1|UniProtKB=W5MEQ1 W5MEQ1 PTHR21600:SF94 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD1 catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011108.1|UniProtKB=W5MZ49 W5MZ49 PTHR11502:SF6 40S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN ES6 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000010357.1|UniProtKB=W5MWC9 W5MWC9 PTHR24340:SF81 HOMEOBOX PROTEIN NKX H6 FAMILY HOMEOBOX 3B transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016217.1|UniProtKB=W5NH87 W5NH87 PTHR10258:SF3 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-4 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459 detection of chemical stimulus#GO:0009593;action potential#GO:0001508;metal ion transport#GO:0030001;response to stimulus#GO:0050896;nervous system process#GO:0050877;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cell communication#GO:0007154;localization#GO:0051179;response to calcium ion#GO:0051592;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;detection of stimulus#GO:0051606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;potassium ion transport#GO:0006813;transport#GO:0006810;response to metal ion#GO:0010038;system process#GO:0003008;transmission of nerve impulse#GO:0019226;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000001100.1|UniProtKB=W5LYN0 W5LYN0 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005227.1|UniProtKB=W5MD59 W5MD59 PTHR13084:SF4 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 1 biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000017889.1|UniProtKB=W5NMY3 W5NMY3 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 14A ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014461.1|UniProtKB=W5NAY9 W5NAY9 PTHR31199:SF1 ARPIN ARPIN regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin nucleation#GO:0051125;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;negative regulation of cytoskeleton organization#GO:0051494 LEPOC|Ensembl=ENSLOCG00000011488.1|UniProtKB=W5N0F9 W5N0F9 PTHR21017:SF19 NIPSNAP-RELATED NIPSNAP HOMOLOG 3A-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;process utilizing autophagic mechanism#GO:0061919;mitophagy#GO:0000423;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012209.1|UniProtKB=W5N312 W5N312 PTHR24248:SF146 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 4 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005788.1|UniProtKB=W5MF32 W5MF32 PTHR10210:SF29 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 2 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004530.1|UniProtKB=W5MAM0 W5MAM0 PTHR11255:SF38 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ALPHA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;neutral lipid metabolic process#GO:0006638;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016742.1|UniProtKB=W5NJ81 W5NJ81 PTHR10256:SF2 SELENIDE, WATER DIKINASE ZINCORE COMPONENT SEPHS1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011329.1|UniProtKB=W5MZX3 W5MZX3 PTHR45691:SF4 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 1 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 LEPOC|Ensembl=ENSLOCG00000000972.1|UniProtKB=W5LY84 W5LY84 PTHR45632:SF18 LD33804P KELCH-LIKE FAMILY MEMBER 43 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;protein metabolic process#GO:0019538;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of JNK cascade#GO:0046328;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006380.1|UniProtKB=W5MH64 W5MH64 PTHR13388:SF4 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132C cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000003792.1|UniProtKB=W5M839 W5M839 PTHR43150:SF1 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-2 alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;protein binding#GO:0005515;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;channel regulator activity#GO:0016247;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;binding#GO:0005488;potassium channel regulator activity#GO:0015459;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108 regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 transmembrane transporter complex#GO:1902495;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;transporter complex#GO:1990351;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;main axon#GO:0044304;neuron projection#GO:0043005;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000013418.1|UniProtKB=W5N7D9 W5N7D9 PTHR44099:SF2 RABCONNECTIN-3B, ISOFORM A WD REPEAT-CONTAINING PROTEIN 72 macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016458.1|UniProtKB=W5NI68 W5NI68 PTHR10841:SF6 SYNAPSIN SYNAPSIN-3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cytoskeletal adaptor activity#GO:0008093 synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;cell junction organization#GO:0034330;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;synapse organization#GO:0050808;organelle localization#GO:0051640 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009444.1|UniProtKB=W5MT33 W5MT33 PTHR46089:SF1 ALSIN HOMOLOG ALS2 C-TERMINAL-LIKE PROTEIN nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000012176.1|UniProtKB=W5N2W5 W5N2W5 PTHR24248:SF169 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 4 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010379.1|UniProtKB=W5MWG1 W5MWG1 PTHR45638:SF8 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL BETA-3 ligand-gated monoatomic ion channel activity#GO:0015276;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261;guanyl nucleotide binding#GO:0019001;gated channel activity#GO:0022836;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;monoatomic ion channel activity#GO:0005216;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;transporter complex#GO:1990351 ligand-gated ion channel#PC00141;ion channel#PC00133 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 LEPOC|Ensembl=ENSLOCG00000002742.1|UniProtKB=W5M4C1 W5M4C1 PTHR23235:SF175 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013811.1|UniProtKB=W5N8S4 W5N8S4 PTHR24214:SF7 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 3 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component organization#GO:0016043;circulatory system development#GO:0072359;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;organelle organization#GO:0006996;cellular process#GO:0009987;heart development#GO:0007507;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010 I band#GO:0031674;actin filament#GO:0005884;stress fiber#GO:0001725;cytoskeleton#GO:0005856;adherens junction#GO:0005912;cell junction#GO:0030054;sarcomere#GO:0030017;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;actomyosin#GO:0042641;cell-cell junction#GO:0005911;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000013441.1|UniProtKB=W5N7G3 W5N7G3 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198 multicellular organismal reproductive process#GO:0048609;binding of sperm to zona pellucida#GO:0007339;anatomical structure development#GO:0048856;cell recognition#GO:0008037;sexual reproduction#GO:0019953;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;reproductive process#GO:0022414;fertilization#GO:0009566;gamete generation#GO:0007276;cell differentiation#GO:0030154;germ cell development#GO:0007281;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;cell-cell recognition#GO:0009988;cellular developmental process#GO:0048869;developmental process#GO:0032502;sperm-egg recognition#GO:0035036;oogenesis#GO:0048477;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;single fertilization#GO:0007338 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 LEPOC|Ensembl=ENSLOCG00000015177.1|UniProtKB=W5NDG6 W5NDG6 PTHR32121:SF0 PCNA-INTERACTING PARTNER PCNA-INTERACTING PARTNER negative regulation of metabolic process#GO:0009892;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;negative regulation of DNA recombination#GO:0045910;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of double-strand break repair via homologous recombination#GO:2000042;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017538.1|UniProtKB=W5NLY4 W5NLY4 PTHR19297:SF96 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000008695.1|UniProtKB=W5MQC1 W5MQC1 PTHR13589:SF6 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 2 protein binding#GO:0005515;transcription coactivator activity#GO:0003713;DNA-binding transcription factor binding#GO:0140297;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;binding#GO:0005488;transcription regulator activity#GO:0140110 positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;cellular response to nitrogen compound#GO:1901699;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007193.1|UniProtKB=W5MJZ4 W5MJZ4 PTHR16551:SF1 AGOUTI RELATED AGOUTI-SIGNALING PROTEIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;neuropeptide receptor binding#GO:0071855;G protein-coupled receptor binding#GO:0001664;neuropeptide hormone activity#GO:0005184;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001846.1|UniProtKB=W5M178 W5M178 PTHR13544:SF7 SELENOPROTEIN T THIOREDOXIN REDUCTASE-LIKE SELENOPROTEIN T1A-RELATED disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 LEPOC|Ensembl=ENSLOCG00000006600.1|UniProtKB=W5MHW0 W5MHW0 PTHR45646:SF6 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK2 catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000014824.1|UniProtKB=W5NC95 W5NC95 PTHR12777:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;U4/U6 x U5 tri-snRNP complex#GO:0046540;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000008119.1|UniProtKB=W5MNA0 W5MNA0 PTHR13385:SF0 AUTOPHAGY PROTEIN 12 UBIQUITIN-LIKE PROTEIN ATG12 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;carbohydrate catabolic process#GO:0016052;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;piecemeal microautophagy of the nucleus#GO:0034727;carbohydrate metabolic process#GO:0005975;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;vacuole organization#GO:0007033;glycogen catabolic process#GO:0005980;macroautophagy#GO:0016236;generation of precursor metabolites and energy#GO:0006091;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170 vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000015941.1|UniProtKB=W5NG68 W5NG68 PTHR45776:SF1 MIP04163P TRANSCRIPTION FACTOR EC sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000010364.1|UniProtKB=W5MWE9 W5MWE9 PTHR23023:SF210 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012390.1|UniProtKB=W5N3P6 W5N3P6 PTHR18945:SF93 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-1 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;anatomical structure development#GO:0048856;localization#GO:0051179;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;system development#GO:0048731;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;synapse assembly#GO:0007416;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;nervous system development#GO:0007399;chloride transport#GO:0006821;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;cell junction#GO:0030054;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;dendrite#GO:0030425;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000017928.1|UniProtKB=W5NN22 W5NN22 PTHR46077:SF1 E3 UBIQUITIN-PROTEIN LIGASE TOPORS E3 UBIQUITIN-PROTEIN LIGASE TOPORS catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007832.1|UniProtKB=W5MM99 W5MM99 PTHR13275:SF4 YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840 ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000018116.1|UniProtKB=W5NNK8 W5NNK8 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017954.1|UniProtKB=W5NN48 W5NN48 PTHR22923:SF102 CEREBELLIN-RELATED CEREBELLIN 10 PRECURSOR-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012001.1|UniProtKB=W5N2A1 W5N2A1 PTHR45652:SF24 GLIAL FIBRILLARY ACIDIC PROTEIN ZGC:136930 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000016821.1|UniProtKB=W5NJI5 W5NJI5 PTHR14463:SF5 LIPASE MATURATION FACTOR LIPASE MATURATION FACTOR 2 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000013236.1|UniProtKB=W5N6Q3 W5N6Q3 PTHR23192:SF75 OLFACTOMEDIN-RELATED ADHESION G PROTEIN-COUPLED RECEPTOR L3 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000015213.1|UniProtKB=W5NDL1 W5NDL1 PTHR11964:SF73 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 nucleotidyltransferase#PC00174;transferase#PC00220 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 LEPOC|Ensembl=ENSLOCG00000010572.1|UniProtKB=W5MX42 W5MX42 PTHR22910:SF7 PROTEIN MGARP PWWP DOMAIN PROTEIN LEPOC|Ensembl=ENSLOCG00000011831.1|UniProtKB=W5N1R8 W5N1R8 PTHR11254:SF443 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;transporter regulator activity#GO:0141108;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;catalytic activity#GO:0003824;transferase activity#GO:0016740 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of dendrite morphogenesis#GO:0048814;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;regulation of developmental process#GO:0050793;macromolecule catabolic process#GO:0009057;regulation of cell projection organization#GO:0031344;metabolic process#GO:0008152;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule metabolic process#GO:0043170;regulation of plasma membrane bounded cell projection organization#GO:0120035;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010863.1|UniProtKB=W5MY58 W5MY58 PTHR48075:SF1 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN LAMBDA-CRYSTALLIN HOMOLOG oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000017029.1|UniProtKB=W5NK88 W5NK88 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 14A ISOFORM X1-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007720.1|UniProtKB=W5MLY3 W5MLY3 PTHR46256:SF4 AGAP011099-PA MYOSIN-IIIA protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;ATP-dependent activity#GO:0140657;protein serine/threonine kinase activity#GO:0004674;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;transferase activity#GO:0016740 positive regulation of cell projection organization#GO:0031346;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;regulation of cell projection assembly#GO:0060491;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;system process#GO:0003008;regulation of filopodium assembly#GO:0051489;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;sensory perception of sound#GO:0007605;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089 intracellular membraneless organelle#GO:0043232;neuron projection#GO:0043005;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;stereocilium#GO:0032420;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;photoreceptor inner segment#GO:0001917;filopodium#GO:0030175;intracellular organelle#GO:0043229 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000010110.1|UniProtKB=W5MVF4 W5MVF4 PTHR36649:SF28 UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000982.1|UniProtKB=W5LY96 W5LY96 PTHR42912:SF93 METHYLTRANSFERASE THIOL S-METHYLTRANSFERASE TMT1A transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824 methyltransferase#PC00155;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000012987.1|UniProtKB=W5N5T3 W5N5T3 PTHR46262:SF3 FORKHEAD BOX PROTEIN BINIOU FORKHEAD BOX PROTEIN F2 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000006221.1|UniProtKB=W5MGK3 W5MGK3 PTHR45996:SF1 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 3 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 LEPOC|Ensembl=ENSLOCG00000003995.1|UniProtKB=W5M8R1 W5M8R1 PTHR11010:SF117 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED SERINE PROTEASE 16 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000012575.1|UniProtKB=W5N4C1 W5N4C1 PTHR10352:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 2 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000003230.1|UniProtKB=W5M608 W5M608 PTHR24061:SF1 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL 2, RECEPTOR 2-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017677.1|UniProtKB=W5NMC3 W5NMC3 PTHR23267:SF486 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14_DELTA VARIABLE 4 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013672.1|UniProtKB=W5N894 W5N894 PTHR10807:SF39 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 10 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;dephosphorylation#GO:0016311;lipid modification#GO:0030258 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000006200.1|UniProtKB=W5MGH9 W5MGH9 PTHR12002:SF9 CLAUDIN CLAUDIN-18 cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000009966.1|UniProtKB=W5MUX8 W5MUX8 PTHR13864:SF15 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 HOMOLOG-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000001758.1|UniProtKB=W5M0W9 W5M0W9 PTHR15481:SF2 RIBONUCLEIC ACID BINDING PROTEIN S1 RNA-BINDING PROTEIN WITH SERINE-RICH DOMAIN 1 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000008788.1|UniProtKB=W5MQN8 W5MQN8 PTHR10165:SF209 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 3 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phospholipid metabolic process#GO:0006644;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;dephosphorylation#GO:0016311;cell communication#GO:0007154;cell adhesion#GO:0007155;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;cell-cell adhesion#GO:0098609;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002092.1|UniProtKB=W5M220 W5M220 PTHR46809:SF1 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000008269.1|UniProtKB=W5MNT2 W5MNT2 PTHR14787:SF1 C10ORF188 FAMILY MEMBER ATPASE PAAT hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000017728.1|UniProtKB=W5NMH3 W5NMH3 PTHR24235:SF15 NEUROPEPTIDE Y RECEPTOR 7 TRANSMEMBRANE RECEPTOR DOMAIN-CONTAINING PROTEIN peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004607.1|UniProtKB=W5MAV8 W5MAV8 PTHR15205:SF1 DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN DNA-BINDING DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN 2 signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;apoptotic signaling pathway#GO:0097190;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell communication#GO:0007154 membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000005132.1|UniProtKB=W5MCU8 W5MCU8 PTHR18952:SF104 CARBONIC ANHYDRASE CARBONIC ANHYDRASE-RELATED PROTEIN positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of calcium-mediated signaling#GO:0050850;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000004613.1|UniProtKB=W5MAW7 W5MAW7 PTHR11636:SF42 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000013083.1|UniProtKB=W5N656 W5N656 PTHR13386:SF1 HISTONE PARYLATION FACTOR 1 HISTONE PARYLATION FACTOR 1 binding#GO:0005488;carbohydrate derivative binding#GO:0097367;histone binding#GO:0042393;protein binding#GO:0005515 cellular response to stress#GO:0033554;response to stimulus#GO:0050896;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;response to stress#GO:0006950;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000004568.1|UniProtKB=W5MAR5 W5MAR5 PTHR22847:SF751 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 DNA-templated transcription initiation#GO:0006352;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;transcription initiation-coupled chromatin remodeling#GO:0045815;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;transcription by RNA polymerase II#GO:0006366 organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;NSL complex#GO:0044545;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Set1C/COMPASS complex#GO:0048188 LEPOC|Ensembl=ENSLOCG00000015827.1|UniProtKB=W5NFS3 W5NFS3 PTHR11635:SF156 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE II-BETA REGULATORY SUBUNIT enzyme inhibitor activity#GO:0004857;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;protein kinase A binding#GO:0051018;carbohydrate derivative binding#GO:0097367;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186 cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;GABA-B receptor II signaling#P05731>PKA#P05752;Endothelin signaling pathway#P00019>PKA#P00570;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Hedgehog signaling pathway#P00025>PKA#P00682;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491 LEPOC|Ensembl=ENSLOCG00000002924.1|UniProtKB=W5M4X9 W5M4X9 PTHR10993:SF12 OCTANOYLTRANSFERASE RIBONUCLEASE P_MRP PROTEIN SUBUNIT POP5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015847.1|UniProtKB=W5NFV7 W5NFV7 PTHR24060:SF26 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 8 glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;glutamate receptor signaling pathway#GO:0007215;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000005967.1|UniProtKB=W5MFQ9 W5MFQ9 PTHR13173:SF10 WW DOMAIN BINDING PROTEIN 4 WW DOMAIN-BINDING PROTEIN 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000004563.1|UniProtKB=W5MAV4 W5MAV4 MYH16 PTHR45615:SF50 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-16 polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000003041.1|UniProtKB=W5M5E7 W5M5E7 PTHR10063:SF0 TUBERIN TUBERIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;signaling#GO:0023052;positive regulation of macroautophagy#GO:0016239;response to stimulus#GO:0050896;negative regulation of TORC1 signaling#GO:1904262;regulation of macroautophagy#GO:0016241;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of autophagy#GO:0010508;intracellular signaling cassette#GO:0141124;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GTPase-activating protein#PC00257;G-protein modulator#PC00022 p53 pathway by glucose deprivation#P04397>TSC2#P04644;p53 pathway by glucose deprivation#P04397>TSC2#G04706;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC2#P04494 LEPOC|Ensembl=ENSLOCG00000005599.1|UniProtKB=W5MEF2 W5MEF2 PTHR46484:SF7 SI:CH211-171H4.5-RELATED MYELIN-ASSOCIATED GLYCOPROTEIN ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000013859.1|UniProtKB=W5N8Y2 W5N8Y2 PTHR14399:SF12 P53-INDUCED PROTEIN RELATED TRANSMEMBRANE PROTEIN 47 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 LEPOC|Ensembl=ENSLOCG00000014389.1|UniProtKB=W5NAQ4 W5NAQ4 PTHR16043:SF1 DALRD3 PROTEIN DALR ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 3 tRNA binding#GO:0000049;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399 LEPOC|Ensembl=ENSLOCG00000008645.1|UniProtKB=W5MQ71 W5MQ71 PTHR11480:SF104 SAPOSIN-RELATED SAPOSIN B-TYPE DOMAIN-CONTAINING PROTEIN primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008970.1|UniProtKB=W5MRF1 W5MRF1 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014526.1|UniProtKB=W5NB66 W5NB66 PTHR24180:SF45 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN 39 kinase modulator#PC00140;kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000011227.1|UniProtKB=W5MZI3 W5MZI3 PTHR31993:SF6 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000004543.1|UniProtKB=W5MAM4 W5MAM4 PTHR15961:SF3 PROTEIN EURL HOMOLOG PROTEIN EURL HOMOLOG multicellular organismal process#GO:0032501;brain development#GO:0007420;nervous system development#GO:0007399;head development#GO:0060322;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;central nervous system neuron differentiation#GO:0021953;neuron differentiation#GO:0030182;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;forebrain development#GO:0030900;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 LEPOC|Ensembl=ENSLOCG00000005548.1|UniProtKB=W5ME85 W5ME85 PTHR11818:SF8 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A3 structural molecule activity#GO:0005198 sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000012032.1|UniProtKB=W5N2E1 W5N2E1 RPSA PTHR11489:SF9 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;translation#GO:0006412;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000008444.1|UniProtKB=W5MPG1 W5MPG1 PTHR16736:SF1 CORTEXIN-1-RELATED CORTEXIN-3 LEPOC|Ensembl=ENSLOCG00000012231.1|UniProtKB=W5N334 W5N334 PTHR11814:SF31 SULFATE TRANSPORTER SULFATE ANION TRANSPORTER 1 chloride transmembrane transporter activity#GO:0015108;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;active transmembrane transporter activity#GO:0022804;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007762.1|UniProtKB=W5MM15 W5MM15 PTHR34756:SF1 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 3 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000010518.1|UniProtKB=W5MWX8 W5MWX8 PTHR15507:SF16 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN 654 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002413.1|UniProtKB=W5M374 W5M374 PTHR24230:SF78 G-PROTEIN COUPLED RECEPTOR KISS-1 RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;positive regulation of signaling#GO:0023056;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of hormone secretion#GO:0046883;regulation of signaling#GO:0023051;positive regulation of hormone secretion#GO:0046887;positive regulation of secretion#GO:0051047;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003925.1|UniProtKB=W5M8H7 W5M8H7 PTHR24366:SF177 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 53 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000001728.1|UniProtKB=W5M0V7 W5M0V7 PTHR36170:SF1 CENTROSOMAL PROTEIN OF 89 KDA CENTROSOMAL PROTEIN OF 89 KDA cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;mitochondrion organization#GO:0007005;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;ciliary transition fiber#GO:0097539;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000012845.1|UniProtKB=W5N5A1 W5N5A1 PTHR14030:SF29 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 BETA protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;chromosome organization#GO:0051276;regulation of mitotic nuclear division#GO:0007088;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;sister chromatid cohesion#GO:0007062;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;cellular process#GO:0009987;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;meiotic sister chromatid cohesion#GO:0051177;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;kinetochore#GO:0000776;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012712.1|UniProtKB=W5N4T2 W5N4T2 PTHR35255:SF1 TRANSMEMBRANE PROTEIN 71 TRANSMEMBRANE PROTEIN 71 LEPOC|Ensembl=ENSLOCG00000004163.1|UniProtKB=W5M9B9 W5M9B9 PTHR13966:SF5 ENDONUCLEASE RELATED ENDONUCLEASE G, MITOCHONDRIAL DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536 cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;catabolic process#GO:0009056;cell death#GO:0008219;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655 organelle membrane#GO:0031090;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;nucleus#GO:0005634;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739 Apoptosis signaling pathway#P00006>endoG#P00279 LEPOC|Ensembl=ENSLOCG00000001413.1|UniProtKB=W5LZQ3 W5LZQ3 PTHR22745:SF0 PROTHYMOSIN ALPHA PROTHYMOSIN ALPHA protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001080.1|UniProtKB=W5LYL0 W5LYL0 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015789.1|UniProtKB=W5NFM9 W5NFM9 PTHR11537:SF287 VOLTAGE-GATED POTASSIUM CHANNEL A-TYPE VOLTAGE-GATED POTASSIUM CHANNEL KCND1 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;action potential#GO:0001508;metal ion transport#GO:0030001;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell junction#GO:0030054;dendritic spine#GO:0043197;plasma membrane protein complex#GO:0098797;cell body#GO:0044297;postsynapse#GO:0098794;membrane protein complex#GO:0098796;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic tree#GO:0097447;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000000117.1|UniProtKB=W5LVH4 W5LVH4 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007756.1|UniProtKB=W5MM10 W5MM10 PTHR11442:SF41 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ZETA heme binding#GO:0020037;binding#GO:0005488;molecular carrier activity#GO:0140104;tetrapyrrole binding#GO:0046906 multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;transport#GO:0006810;developmental process#GO:0032502;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;localization#GO:0051179;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219;globin#PC00107 LEPOC|Ensembl=ENSLOCG00000008408.1|UniProtKB=W5MPB0 W5MPB0 PTHR10290:SF26 DNA TOPOISOMERASE I DNA TOPOISOMERASE I, MITOCHONDRIAL ISOFORM X1 isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;chromosome segregation#GO:0007059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 DNA topoisomerase#PC00017;DNA metabolism protein#PC00009 Huntington disease#P00029>Actin#P00807;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cadherin signaling pathway#P00012>F-actin#P00470 LEPOC|Ensembl=ENSLOCG00000009328.1|UniProtKB=W5MSL8 W5MSL8 PTHR47065:SF3 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9 EF-HAND DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 sperm motility#GO:0097722;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;flagellated sperm motility#GO:0030317;microtubule-based process#GO:0007017;cilium-dependent cell motility#GO:0060285 cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;sperm principal piece#GO:0097228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;9+2 motile cilium#GO:0097729;cilium#GO:0005929 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000007964.1|UniProtKB=W5MMR7 W5MMR7 PTHR12411:SF1048 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN K catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010909.1|UniProtKB=W5MYD5 W5MYD5 PTHR24095:SF83 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 nucleoside phosphate biosynthetic process#GO:1901293;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000007727.1|UniProtKB=W5MLZ2 W5MLZ2 ELOVL7 PTHR11157:SF118 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 7 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000003569.1|UniProtKB=W5M771 W5M771 PTHR46135:SF4 NME/NM23 FAMILY MEMBER 8 DYNEIN AXONEMAL ASSEMBLY FACTOR 8 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000014907.1|UniProtKB=W5NCK3 W5NCK3 PTHR11958:SF19 SODIUM/DICARBOXYLATE SYMPORTER-RELATED NEUTRAL AMINO ACID TRANSPORTER B(0) L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;C4-dicarboxylate transmembrane transporter activity#GO:0015556;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;L-alpha-amino acid transmembrane transport#GO:1902475;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179;L-glutamate import#GO:0051938;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;aspartate transmembrane transport#GO:0015810;L-amino acid transport#GO:0015807;establishment of localization#GO:0051234;import into cell#GO:0098657;amino acid transport#GO:0006865;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;carboxylic acid transport#GO:0046942 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000010570.1|UniProtKB=W5MX40 W5MX40 PTHR11309:SF150 FRIZZLED FRIZZLED CLASS RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;non-canonical Wnt signaling pathway#GO:0035567;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016020.1|UniProtKB=W5NGH3 W5NGH3 PTHR10971:SF2 MRNA EXPORT FACTOR AND BUB3 DYNEIN AXONEMAL ASSEMBLY FACTOR 10 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013779.1|UniProtKB=W5N8N6 W5N8N6 PTHR23389:SF21 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 5 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000009304.1|UniProtKB=W5MSI8 W5MSI8 PTHR47633:SF8 IMMUNOGLOBULIN SPEG NEIGHBOR PROTEIN LEPOC|Ensembl=ENSLOCG00000007459.1|UniProtKB=W5MKZ3 W5MKZ3 PTHR19143:SF479 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN 4 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000013497.1|UniProtKB=W5N7N8 W5N7N8 PTHR10288:SF92 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;developmental process#GO:0032502;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;cytosol#GO:0005829;nucleus#GO:0005634;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005337.1|UniProtKB=W5MDH3 W5MDH3 PTHR13844:SF1 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000016099.1|UniProtKB=W5NGS5 W5NGS5 PTHR24248:SF16 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1A ADRENERGIC RECEPTOR G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of biological quality#GO:0065008;adrenergic receptor signaling pathway#GO:0071875;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 LEPOC|Ensembl=ENSLOCG00000004614.1|UniProtKB=W5MAW6 W5MAW6 PTHR23505:SF79 SPINSTER PROTEIN SPINSTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003037.1|UniProtKB=W5M5D0 W5M5D0 PTHR11959:SF11 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000006031.1|UniProtKB=W5MFX8 W5MFX8 PTHR10884:SF17 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000004658.1|UniProtKB=W5MB75 W5MB75 PTHR13817:SF96 TITIN NEURAL CELL ADHESION MOLECULE 1 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011312.1|UniProtKB=W5MZU3 W5MZU3 PTHR23055:SF13 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 1 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;molecular function activator activity#GO:0140677;cation binding#GO:0043169;enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851;molecular function regulator activity#GO:0098772 sensory perception of light stimulus#GO:0050953;sensory perception#GO:0007600;nervous system process#GO:0050877;visual perception#GO:0007601;multicellular organismal process#GO:0032501;system process#GO:0003008 cilium#GO:0005929;photoreceptor inner segment#GO:0001917;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;9+0 non-motile cilium#GO:0097731;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;photoreceptor outer segment#GO:0001750;organelle#GO:0043226 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000009979.1|UniProtKB=W5MUZ3 W5MUZ3 PTHR11849:SF182 ETS SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000009678.1|UniProtKB=W5MTX6 W5MTX6 PTHR10502:SF17 ANNEXIN ANNEXIN A1 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phospholipid binding#GO:0005543 regulation of cellular process#GO:0050794;endocytosis#GO:0006897;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;localization#GO:0051179;cell communication#GO:0007154;response to steroid hormone#GO:0048545;cellular response to chemical stimulus#GO:0070887;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular response to steroid hormone stimulus#GO:0071383;phagocytosis#GO:0006909;transport#GO:0006810 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;nucleus#GO:0005634 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000004374.1|UniProtKB=W5MA38 W5MA38 PTHR11905:SF20 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 8 protein binding#GO:0005515;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;binding#GO:0005488;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;cell adhesion molecule binding#GO:0050839;catalytic activity#GO:0003824 regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;defense response#GO:0006952;regulation of catabolic process#GO:0009894;positive regulation of locomotion#GO:0040017;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of cell migration#GO:0030334;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of leukocyte migration#GO:0002685;primary metabolic process#GO:0044238;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;protein metabolic process#GO:0019538;regulation of cell motility#GO:2000145;inflammatory response#GO:0006954;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;regulation of proteolysis#GO:0030162;metabolic process#GO:0008152;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;proteolysis#GO:0006508 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000003993.1|UniProtKB=W5M8Q9 W5M8Q9 PTHR11675:SF38 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 17 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009049.1|UniProtKB=W5MRM3 W5MRM3 PTHR10890:SF27 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000013732.1|UniProtKB=W5N8H4 W5N8H4 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;aminoglycan biosynthetic process#GO:0006023;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011654.1|UniProtKB=W5N111 W5N111 PTHR23122:SF33 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 3 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003414.1|UniProtKB=W5M6N2 W5M6N2 PTHR23192:SF68 OLFACTOMEDIN-RELATED OLFACTOMEDIN-4-RELATED cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000017077.1|UniProtKB=W5NKE4 W5NKE4 PTHR22738:SF8 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 3 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002737.1|UniProtKB=W5M4B9 W5M4B9 PTHR11528:SF44 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN 75 KDA, MITOCHONDRIAL-RELATED ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;protein kinase binding#GO:0019901;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072;Hsp90 family chaperone#PC00028 LEPOC|Ensembl=ENSLOCG00000010275.1|UniProtKB=W5MW34 W5MW34 PTHR24020:SF37 COLLAGEN ALPHA VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 2 cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000017014.1|UniProtKB=W5NK73 W5NK73 PTHR45915:SF4 TRANSCRIPTION INTERMEDIARY FACTOR TRANSCRIPTION INTERMEDIARY FACTOR 1-ALPHA transcription coregulator activity#GO:0003712;transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;transcription regulator activity#GO:0140110;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein stability#GO:0031647;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003341.1|UniProtKB=W5M6E3 W5M6E3 PTHR45836:SF2 SLIT HOMOLOG SLIT HOMOLOG 2 PROTEIN signaling receptor binding#GO:0005102;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;heparin binding#GO:0008201;protein binding#GO:0005515 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cell growth#GO:0001558;taxis#GO:0042330;response to chemical#GO:0042221;chemotaxis#GO:0006935;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of growth#GO:0040008;locomotion#GO:0040011;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;negative regulation of cellular process#GO:0048523;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;negative regulation of cell growth#GO:0030308;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 LEPOC|Ensembl=ENSLOCG00000011444.1|UniProtKB=W5N0A6 W5N0A6 PTHR46228:SF3 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000005969.1|UniProtKB=W5MFT0 W5MFT0 PTHR31043:SF3 NEPHROCYSTIN-4 NEPHROCYSTIN-4 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;localization#GO:0051179;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;protein localization to cilium#GO:0061512;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular membraneless organelle#GO:0043232;ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815 LEPOC|Ensembl=ENSLOCG00000002087.1|UniProtKB=W5M261 W5M261 PTHR45674:SF20 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 3 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on DNA#GO:0140097 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA ligase#PC00012;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011880.1|UniProtKB=W5N1V3 W5N1V3 PTHR14885:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43 gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283 cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008565.1|UniProtKB=W5MPV7 W5MPV7 PTHR12824:SF2 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GROUP XIIB SECRETORY PHOSPHOLIPASE A2-LIKE PROTEIN lipid homeostasis#GO:0055088;triglyceride homeostasis#GO:0070328;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;homeostatic process#GO:0042592 phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014892.1|UniProtKB=W5NCH7 W5NCH7 PTHR11753:SF6 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-2 COMPLEX SUBUNIT SIGMA vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000016494.1|UniProtKB=W5NIC0 W5NIC0 PTHR46513:SF40 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6 nervous system development#GO:0007399;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>LRP5/6#P01431;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 LEPOC|Ensembl=ENSLOCG00000010353.1|UniProtKB=W5MWD5 W5MWD5 PTHR11537:SF182 VOLTAGE-GATED POTASSIUM CHANNEL A-TYPE VOLTAGE-GATED POTASSIUM CHANNEL KCND3 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transport#GO:0006813;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;action potential#GO:0001508;export from cell#GO:0140352;metal ion transport#GO:0030001;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812 transmembrane transporter complex#GO:1902495;dendritic tree#GO:0097447;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell body#GO:0044297;dendritic spine#GO:0043197;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;synaptic membrane#GO:0097060;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000011024.1|UniProtKB=W5MYR9 W5MYR9 PTHR23227:SF87 BUCENTAUR RELATED PROTEIN CFDP2 LEPOC|Ensembl=ENSLOCG00000017152.1|UniProtKB=W5NKN7 W5NKN7 PTHR43979:SF1 PRE-MRNA-PROCESSING FACTOR 17 PRE-MRNA-PROCESSING FACTOR 17 mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000013668.1|UniProtKB=W5N890 W5N890 PTHR22420:SF2 PROTEIN FAM81A PROTEIN FAM81A LEPOC|Ensembl=ENSLOCG00000004962.1|UniProtKB=W5MC70 W5MC70 PTHR11315:SF20 PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE GAMMA-GLUTAMYL HYDROLASE cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000003493.1|UniProtKB=W5M708 W5M708 PTHR22762:SF133 ALPHA-GLUCOSIDASE MALTASE-GLUCOAMYLASE-RELATED hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 glucosidase#PC00108 LEPOC|Ensembl=ENSLOCG00000009683.1|UniProtKB=W5MTX0 W5MTX0 PTHR22747:SF42 NUCLEOPLASMIN NUCLEOPHOSMIN binding#GO:0005488;nucleic acid binding#GO:0003676;histone binding#GO:0042393;chromatin binding#GO:0003682;protein binding#GO:0005515;RNA binding#GO:0003723 chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nuclear transport#GO:0051169;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;regulation of microtubule-based process#GO:0032886;organelle localization#GO:0051640;regulation of cell cycle process#GO:0010564;positive regulation of macromolecule metabolic process#GO:0010604;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cell cycle#GO:0051726;chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;establishment of organelle localization#GO:0051656;ribosomal large subunit export from nucleus#GO:0000055;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular localization#GO:0051641;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000010606.1|UniProtKB=W5MX83 W5MX83 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013721.1|UniProtKB=W5N8G1 W5N8G1 PTHR16155:SF3 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014833.1|UniProtKB=W5NCA8 W5NCA8 PTHR12283:SF6 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIKE PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;zinc ion binding#GO:0008270;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;acyltransferase activity#GO:0016746;cation binding#GO:0043169;metal ion binding#GO:0046872 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004031.1|UniProtKB=W5M8W3 W5M8W3 PTHR45838:SF3 HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER HISTONE-LYSINE N-METHYLTRANSFERASE 2B transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;histone H3K4 methyltransferase activity#GO:0042800;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993 positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000010011.1|UniProtKB=W5MV33 W5MV33 COQ2 PTHR11048:SF42 PRENYLTRANSFERASES 4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 ketone metabolic process#GO:0042180;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;cell periphery#GO:0071944;mitochondrial envelope#GO:0005740;plasma membrane#GO:0005886;cytoplasm#GO:0005737;organelle membrane#GO:0031090 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000014687.1|UniProtKB=W5NBS1 W5NBS1 PTHR23065:SF51 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 1 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003336.1|UniProtKB=W5M6D5 W5M6D5 PTHR22145:SF2 SI:CH211-266K22.6 PROTEIN FAM217B ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000000928.1|UniProtKB=W5LY60 W5LY60 PTHR24044:SF495 NOTCH LIGAND FAMILY MEMBER ATTRACTIN binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015937.1|UniProtKB=W5NG63 W5NG63 PTHR24240:SF2 OPSIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;detection of stimulus#GO:0051606;cellular process#GO:0009987;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;signal transduction#GO:0007165;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;signaling#GO:0023052;cellular response to radiation#GO:0071478;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000916.1|UniProtKB=W5LY14 W5LY14 PTHR47735:SF14 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1 transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000015480.1|UniProtKB=W5NEJ3 W5NEJ3 PTHR12705:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;nuclear origin of replication recognition complex#GO:0005664 replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000005145.1|UniProtKB=W5MCT2 W5MCT2 PTHR16083:SF87 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 20 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012142.1|UniProtKB=W5N2S7 W5N2S7 PTHR24340:SF31 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-6.1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002130.1|UniProtKB=W5M280 W5M280 PTHR11208:SF45 RNA-BINDING PROTEIN RELATED SPLICING FACTOR 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000006029.1|UniProtKB=W5MFX0 W5MFX0 PTHR13068:SF203 CGI-12 PROTEIN-RELATED TRANSCRIPTION TERMINATION FACTOR 4, MITOCHONDRIAL negative regulation of biological process#GO:0048519;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;mitochondrial ribosome assembly#GO:0061668;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000014462.1|UniProtKB=W5NB03 W5NB03 PTHR11533:SF259 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;catabolic process#GO:0009056;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010029.1|UniProtKB=W5MV51 W5MV51 PTHR22961:SF17 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 1 protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 regulation of biological process#GO:0050789;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;biological regulation#GO:0065007;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000010260.1|UniProtKB=W5MW03 W5MW03 PTHR22647:SF3 SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010733.1|UniProtKB=W5MXN6 W5MXN6 PTHR24246:SF1 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000012934.1|UniProtKB=W5N5M7 W5N5M7 PTHR24417:SF0 SERINE/THREONINE-PROTEIN KINASE LMTK1 SERINE_THREONINE-PROTEIN KINASE LMTK1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental process#GO:0032502;brain development#GO:0007420;multicellular organismal process#GO:0032501;head development#GO:0060322;nervous system development#GO:0007399;cellular process#GO:0009987;neuron apoptotic process#GO:0051402;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;central nervous system development#GO:0007417;programmed cell death#GO:0012501;apoptotic process#GO:0006915;cell death#GO:0008219 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001280.1|UniProtKB=W5LZ92 W5LZ92 PTHR21212:SF0 BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN SEIPIN cellular component organization#GO:0016043;organelle organization#GO:0006996;lipid droplet organization#GO:0034389;cellular process#GO:0009987;lipid storage#GO:0019915;cellular component organization or biogenesis#GO:0071840 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000003162.1|UniProtKB=W5M5S8 W5M5S8 PTHR11850:SF59 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000000969.1|UniProtKB=W5LY97 W5LY97 PTHR15680:SF21 RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007588.1|UniProtKB=W5MLF1 W5MLF1 PTHR22826:SF210 RHO GUANINE EXCHANGE FACTOR-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR (GEF) 25B-RELATED molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000013658.1|UniProtKB=W5N880 W5N880 PTHR13165:SF0 ARSENITE-RESISTANCE PROTEIN 2 SERRATE RNA EFFECTOR MOLECULE HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;primary miRNA processing#GO:0031053;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nuclear body#GO:0016604;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000012336.1|UniProtKB=W5N3H4 W5N3H4 PTHR15422:SF9 OS05G0565100 PROTEIN TRANSMEMBRANE REDUCTASE CYB561D1-RELATED LEPOC|Ensembl=ENSLOCG00000013473.1|UniProtKB=W5N7L1 W5N7L1 PTHR31915:SF10 SKICH DOMAIN-CONTAINING PROTEIN CALCIUM-BINDING AND COILED-COIL DOMAIN 2 LEPOC|Ensembl=ENSLOCG00000017545.1|UniProtKB=W5NLZ1 W5NLZ1 PTHR16840:SF7 GROWTH ARREST-SPECIFIC PROTEIN 1 GROWTH ARREST-SPECIFIC 1B biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000017363.1|UniProtKB=W5NLF9 W5NLF9 PTHR10155:SF15 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 5 signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 LEPOC|Ensembl=ENSLOCG00000014441.1|UniProtKB=W5NAX6 W5NAX6 PTHR23182:SF6 BREAKPOINT CLUSTER REGION PROTEIN BCR ACTIVE BREAKPOINT CLUSTER REGION-RELATED PROTEIN ISOFORM X1 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 postsynaptic density#GO:0014069;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;plasma membrane#GO:0005886;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000009985.1|UniProtKB=W5MV02 W5MV02 PTHR28489:SF3 RENTINAL DEGENERATION 3-LIKE PROTEIN RD3-LIKE LEPOC|Ensembl=ENSLOCG00000011441.1|UniProtKB=W5N0A2 W5N0A2 PTHR23222:SF0 PROHIBITIN PROHIBITIN 1 LEPOC|Ensembl=ENSLOCG00000014764.1|UniProtKB=W5NC26 W5NC26 PTHR13720:SF22 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004620.1|UniProtKB=W5MAX7 W5MAX7 PTHR21119:SF7 C2 DOMAIN-CONTAINING PROTEIN C2 DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000005202.1|UniProtKB=W5MD07 W5MD07 PTHR11254:SF127 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HECW2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 biological regulation#GO:0065007;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cell projection organization#GO:0031344;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of dendrite morphogenesis#GO:0048814;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008192.1|UniProtKB=W5MNI9 W5MNI9 PTHR24221:SF165 ATP-BINDING CASSETTE SUB-FAMILY B BILE SALT EXPORT PUMP primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000007442.1|UniProtKB=W5MKX8 W5MKX8 PTHR12308:SF15 ANOCTAMIN ANOCTAMIN intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011233.1|UniProtKB=W5MZJ2 W5MZJ2 PTHR24025:SF31 DESMOGLEIN FAMILY MEMBER NEURAL-CADHERIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000017093.1|UniProtKB=W5NKG8 W5NKG8 PTHR12482:SF40 LIPASE ROG1-RELATED-RELATED PROTEIN FAM135A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000006283.1|UniProtKB=W5MGT2 W5MGT2 PTHR22891:SF46 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 1 endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 sexual reproduction#GO:0019953;piRNA processing#GO:0034587;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental process#GO:0032502;spermatogenesis#GO:0007283;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;male gamete generation#GO:0048232;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000002842.1|UniProtKB=W5M4N3 W5M4N3 PTHR48051:SF77 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 30A cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011628.1|UniProtKB=W5N0Y1 W5N0Y1 PTHR24082:SF15 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217 negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;multicellular organismal-level homeostasis#GO:0048871;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of lipid metabolic process#GO:0019216;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 C4 zinc finger nuclear receptor#PC00169 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000016187.1|UniProtKB=W5NH45 W5NH45 PTHR11532:SF84 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE M catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009289.1|UniProtKB=W5MSG7 W5MSG7 PTHR14636:SF1 TPA-INDUCED TRANSMEMBRANE PROTEIN TPA-INDUCED TRANSMEMBRANE PROTEIN LEPOC|Ensembl=ENSLOCG00000009403.1|UniProtKB=W5MSW4 W5MSW4 PTHR23166:SF4 FILAMIN/GPBP-INTERACTING PROTEIN FILAMIN A-INTERACTING PROTEIN 1-LIKE protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to cytoskeleton#GO:0044380;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012048.1|UniProtKB=W5N2G2 W5N2G2 PTHR10075:SF23 BASIGIN RELATED MYOTILIN cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000140.1|UniProtKB=W5LVJ4 W5LVJ4 PTHR47306:SF2 SI:CH211-178J18.4-RELATED SET DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014942.1|UniProtKB=W5NCN7 W5NCN7 PTHR45877:SF4 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 Wnt signaling pathway#P00057>SIAH-1#P01433 LEPOC|Ensembl=ENSLOCG00000003930.1|UniProtKB=W5M8I9 W5M8I9 PTHR11675:SF37 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 18 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000003203.1|UniProtKB=W5M5Y1 W5M5Y1 PTHR34524:SF6 CALCYPHOSIN CALCYPHOSINE LIKE calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000001839.1|UniProtKB=W5M190 W5M190 PTHR43788:SF9 DNA2/NAM7 HELICASE FAMILY MEMBER 3'-5' EXORIBONUCLEASE HELZ2 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stress#GO:0006950;response to stimulus#GO:0050896 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011912.1|UniProtKB=W5N1Y6 W5N1Y6 PTHR13318:SF50 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000010175.1|UniProtKB=W5MVP8 W5MVP8 PTHR12374:SF63 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-BETA transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;binding#GO:0005488;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338 chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002752.1|UniProtKB=W5M4E0 W5M4E0 PTHR11827:SF6 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 8 active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;symporter activity#GO:0015293 monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transport#GO:0006813;cellular process#GO:0009987 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000006839.1|UniProtKB=W5MIR0 W5MIR0 PTHR14102:SF9 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG ALPHA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell junction organization#GO:0034330;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cell-cell junction maintenance#GO:0045217;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;establishment or maintenance of cell polarity#GO:0007163;cell-cell junction organization#GO:0045216 cell cortex#GO:0005938;apical plasma membrane#GO:0016324;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;apical part of cell#GO:0045177;transferase complex#GO:1990234;protein kinase complex#GO:1902911 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000010226.1|UniProtKB=W5MVV7 W5MVV7 PTHR24056:SF177 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012186.1|UniProtKB=W5N2X7 W5N2X7 PTHR46016:SF4 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF166 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000016554.1|UniProtKB=W5NII5 W5NII5 PTHR35541:SF1 RAD9, HUS1, RAD1-INTERACTING NUCLEAR ORPHAN PROTEIN 1 RAD9, HUS1, RAD1-INTERACTING NUCLEAR ORPHAN PROTEIN 1 cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;DNA integrity checkpoint signaling#GO:0031570;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of cell cycle#GO:0045786 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000003075.1|UniProtKB=W5M5I3 W5M5I3 PTHR23280:SF20 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 3 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 LEPOC|Ensembl=ENSLOCG00000015812.1|UniProtKB=W5NFQ8 W5NFQ8 PTHR12701:SF5 BCR-ASSOCIATED PROTEIN, BAP B-CELL RECEPTOR-ASSOCIATED PROTEIN 29 protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657 response to stimulus#GO:0050896;regulation of biological process#GO:0050789;protein transport#GO:0015031;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;proteasomal protein catabolic process#GO:0010498;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;macromolecule catabolic process#GO:0009057;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;primary metabolic process#GO:0044238;regulation of protein catabolic process#GO:0042176;ERAD pathway#GO:0036503;positive regulation of protein catabolic process#GO:0045732;protein metabolic process#GO:0019538;localization#GO:0051179;response to endoplasmic reticulum stress#GO:0034976;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;intracellular protein localization#GO:0008104;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008395.1|UniProtKB=W5MP92 W5MP92 PTHR19143:SF332 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN BETA CHAIN platelet aggregation#GO:0070527;metabolic process#GO:0008152;blood coagulation#GO:0007596;macromolecule metabolic process#GO:0043170;platelet activation#GO:0030168;coagulation#GO:0050817;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to wounding#GO:0009611;cell-cell adhesion#GO:0098609;response to stress#GO:0006950;biological regulation#GO:0065007;biosynthetic process#GO:0009058;homotypic cell-cell adhesion#GO:0034109;gene expression#GO:0010467;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell activation#GO:0001775;blood coagulation, fibrin clot formation#GO:0072378;regulation of biological quality#GO:0065008;wound healing#GO:0042060;cell-substrate adhesion#GO:0031589;protein activation cascade#GO:0072376;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;hemostasis#GO:0007599;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443;Blood coagulation#P00011>Fibrinogen#P00406;Blood coagulation#P00011>Fibrin monomer#P00418 LEPOC|Ensembl=ENSLOCG00000017535.1|UniProtKB=W5NLY1 W5NLY1 PTHR24070:SF178 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS2 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000002640.1|UniProtKB=W5M421 W5M421 PTHR22772:SF4 NOVEL ZZ TYPE ZINC FINGER DOMAIN CONTAINING PROTEIN ZINC FINGER ZZ-TYPE AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010804.1|UniProtKB=W5MXX7 W5MXX7 PTHR36690:SF2 PROTEIN FAM237A PROTEIN FAM237A LEPOC|Ensembl=ENSLOCG00000004522.1|UniProtKB=W5MAK1 W5MAK1 PTHR28360:SF1 DYNACTIN SUBUNIT 3 DYNACTIN SUBUNIT 3 cell cycle#GO:0007049;cytokinesis#GO:0000910;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301;cytoskeleton-dependent cytokinesis#GO:0061640 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000018142.1|UniProtKB=W5NNN4 W5NNN4 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000001055.1|UniProtKB=W5LYL3 W5LYL3 PTHR15905:SF5 GOLGI-ASSOCIATED KINASE 1B-RELATED GOLGI-ASSOCIATED KINASE 1A organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010077.1|UniProtKB=W5MVD4 W5MVD4 PTHR11647:SF54 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;dihydropyrimidinase activity#GO:0004157;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleobase catabolic process#GO:0046113;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339 LEPOC|Ensembl=ENSLOCG00000010309.1|UniProtKB=W5MW71 W5MW71 PTHR22999:SF43 PX SERINE/THREONINE KINASE PXK SORTING NEXIN-16 anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;ion binding#GO:0043167 intracellular transport#GO:0046907;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;metabolic process#GO:0008152;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;cellular localization#GO:0051641;macromolecule metabolic process#GO:0043170;localization#GO:0051179;endosomal transport#GO:0016197;early endosome to late endosome transport#GO:0045022;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;late endosome#GO:0005770 LEPOC|Ensembl=ENSLOCG00000007527.1|UniProtKB=W5ML73 W5ML73 PTHR24543:SF295 MULTICOPPER OXIDASE-RELATED RETINOSCHISIN sensory organ development#GO:0007423;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;camera-type eye morphogenesis#GO:0048593;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;retina development in camera-type eye#GO:0060041;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;visual system development#GO:0150063 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013744.1|UniProtKB=W5N8I6 W5N8I6 PTHR45716:SF10 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000000626.1|UniProtKB=W5LX35 W5LX35 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017461.1|UniProtKB=W5NLQ7 W5NLQ7 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005040.1|UniProtKB=W5MCG5 W5MCG5 PTHR23157:SF24 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GOLGIN SUBFAMILY A MEMBER 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000003423.1|UniProtKB=W5M6Q7 W5M6Q7 PTHR14343:SF3 VWFA DOMAIN-CONTAINING PROTEIN SIMILAR TO HUMAN CHROMOSOME 11 OPEN READING FRAME 16 LEPOC|Ensembl=ENSLOCG00000002658.1|UniProtKB=W5M425 W5M425 PTHR15742:SF6 GIRDIN MICROTUBULE CROSS-LINKING FACTOR 1 ISOFORM X1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular component organization or biogenesis#GO:0071840;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of bipolar cell polarity#GO:0061245;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 LEPOC|Ensembl=ENSLOCG00000017336.1|UniProtKB=W5NLD2 W5NLD2 PTHR21461:SF45 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008600.1|UniProtKB=W5MQ03 W5MQ03 PTHR15574:SF39 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 6 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000000919.1|UniProtKB=W5LY19 W5LY19 PTHR46160:SF9 ALPHA-TECTORIN-RELATED DENDRITE EXTENSION DEFECTIVE PROTEIN 1-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000013726.1|UniProtKB=W5N8H1 W5N8H1 PTHR23215:SF4 ZINC FINGER PROTEIN 207 BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cell cycle checkpoint signaling#GO:0000075;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;attachment of spindle microtubules to kinetochore#GO:0008608;spindle assembly#GO:0051225;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of cell cycle#GO:0045786;microtubule-based process#GO:0007017;metaphase chromosome alignment#GO:0051310;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic sister chromatid separation#GO:0010965;spindle organization#GO:0007051;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;microtubule cytoskeleton organization involved in mitosis#GO:1902850;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;organelle localization#GO:0051640;negative regulation of chromosome organization#GO:2001251;organelle assembly#GO:0070925;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;negative regulation of chromosome segregation#GO:0051985;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;mitotic spindle organization#GO:0007052;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;nuclear division#GO:0000280;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;chromosome organization#GO:0051276;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of mitotic sister chromatid segregation#GO:0033047 chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001458.1|UniProtKB=W5LZV6 W5LZV6 PTHR12458:SF11 ORF PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 20 cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722;anatomical structure morphogenesis#GO:0009653;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;motile cilium assembly#GO:0044458;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;microtubule-based process#GO:0007017;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;multicellular organismal process#GO:0032501;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;sperm flagellum#GO:0036126;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;microtubule#GO:0005874;intracellular organelle#GO:0043229;cilium#GO:0005929;9+2 motile cilium#GO:0097729 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 LEPOC|Ensembl=ENSLOCG00000004932.1|UniProtKB=W5MC23 W5MC23 PTHR12357:SF9 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-RNA adaptor activity#GO:0140517;RNA binding#GO:0003723 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007125.1|UniProtKB=W5MJR6 W5MJR6 PTHR11422:SF19 T-CELL SURFACE GLYCOPROTEIN CD4 LYMPHOCYTE ACTIVATION GENE 3 PROTEIN ISOFORM X1 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012352.1|UniProtKB=W5N3K5 W5N3K5 PTHR45888:SF10 HL01030P-RELATED ZINC FINGER PROTEIN DPF3 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000000209.1|UniProtKB=W5LVS6 W5LVS6 PTHR43827:SF10 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE ZGC:110366 reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000008105.1|UniProtKB=W5MN84 W5MN84 PTHR34768:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 89 COILED-COIL DOMAIN CONTAINING 89 LEPOC|Ensembl=ENSLOCG00000009580.1|UniProtKB=W5MTJ7 W5MTJ7 PTHR21663:SF1 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5A cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004906.1|UniProtKB=W5MBZ5 W5MBZ5 PTHR10285:SF68 URIDINE KINASE URIDINE-CYTIDINE KINASE-LIKE 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150 LEPOC|Ensembl=ENSLOCG00000015058.1|UniProtKB=W5ND27 W5ND27 PTHR19134:SF285 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 9 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006116.1|UniProtKB=W5MG83 W5MG83 PTHR19367:SF18 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 18 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012187.1|UniProtKB=W5N2Y1 W5N2Y1 PTHR11347:SF115 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 eye development#GO:0001654;negative regulation of cell communication#GO:0010648;system development#GO:0048731;negative regulation of intracellular signal transduction#GO:1902532;anatomical structure development#GO:0048856;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;camera-type eye development#GO:0043010;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;visual system development#GO:0150063;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;sensory organ development#GO:0007423;retina development in camera-type eye#GO:0060041;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;sensory system development#GO:0048880 plasma membrane region#GO:0098590;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929 phosphodiesterase#PC00185;hydrolase#PC00121 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEalphabeta#P00759 LEPOC|Ensembl=ENSLOCG00000007543.1|UniProtKB=W5ML90 W5ML90 PTHR15283:SF5 GREMLIN 1 NEUROBLASTOMA SUPPRESSOR OF TUMORIGENICITY 1 binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine binding#GO:0019955 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008556.1|UniProtKB=W5MPV2 W5MPV2 PTHR11523:SF10 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1 ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 export from cell#GO:0140352;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003 ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012149.1|UniProtKB=W5N2V4 W5N2V4 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011000.1|UniProtKB=W5MYN6 W5MYN6 PTHR19269:SF46 TROPOMYOSIN TROPOMYOSIN BETA CHAIN actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;muscle contraction#GO:0006936;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;muscle system process#GO:0003012;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;multicellular organismal process#GO:0032501 intracellular organelle#GO:0043229;actin filament#GO:0005884;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000008550.1|UniProtKB=W5MPU7 W5MPU7 PTHR24291:SF216 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450, FAMILY 4, SUBFAMILY B, POLYPEPTIDE 7 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000013437.1|UniProtKB=W5N7F9 W5N7F9 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 ISOFORM X1 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000008608.1|UniProtKB=W5MQ17 W5MQ17 PTHR11412:SF86 MACROGLOBULIN / COMPLEMENT COMPLEMENT C4-A-RELATED chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000013254.1|UniProtKB=W5N6T1 W5N6T1 PTHR15593:SF2 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 5 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 G protein-coupled receptor signaling pathway#GO:0007186;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;EGF receptor signaling pathway#P00018>PI3K#P00557;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PDGF signaling pathway#P00047>PI3K#P01168;p53 pathway feedback loops 2#P04398>PI3K#P04661;PI3 kinase pathway#P00048>p101#P01203;Axon guidance mediated by netrin#P00009>PI3K#P00363 LEPOC|Ensembl=ENSLOCG00000013208.1|UniProtKB=W5N6L1 W5N6L1 PTHR10556:SF27 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE TRANS-2,3-ENOYL-COA REDUCTASE-LIKE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014699.1|UniProtKB=W5NBT8 W5NBT8 PTHR12210:SF3 DULLARD PROTEIN PHOSPHATASE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM50 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000014329.1|UniProtKB=W5NAI3 W5NAI3 PTHR45711:SF7 CHLORIDE CHANNEL PROTEIN H(+)_CL(-) EXCHANGE TRANSPORTER 5 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic anion channel activity#GO:0008308;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 monoatomic anion transmembrane transport#GO:0098656;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;renal system process#GO:0003014;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;system process#GO:0003008;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;transport#GO:0006810 endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007451.1|UniProtKB=W5MKZ1 W5MKZ1 PTHR24356:SF153 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 32C transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000009853.1|UniProtKB=W5MUI5 W5MUI5 PTHR12479:SF6 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4B regulation of membrane permeability#GO:0090559;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002380.1|UniProtKB=W5M337 W5M337 PTHR12461:SF43 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HSPB1-ASSOCIATED PROTEIN 1 dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003614.1|UniProtKB=W5M7C8 W5M7C8 PTHR11108:SF1 FERROCHELATASE FERROCHELATASE, MITOCHONDRIAL lyase activity#GO:0016829;catalytic activity#GO:0003824 metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;porphyrin-containing compound biosynthetic process#GO:0006779;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 lyase#PC00144 Heme biosynthesis#P02746>Ferrochelatase#P02972 LEPOC|Ensembl=ENSLOCG00000001920.1|UniProtKB=W5M1I5 W5M1I5 PTHR46501:SF2 MYOMEGALIN MYOMEGALIN microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;centrosome cycle#GO:0007098;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;cell cycle#GO:0007049;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011829.1|UniProtKB=W5N1P3 W5N1P3 PTHR10217:SF468 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED INWARDLY RECTIFYING POTASSIUM CHANNEL KCNH6 transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;biological regulation#GO:0065007;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000018272.1|UniProtKB=W5NP14 W5NP14 PTHR28599:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 12 SMALL INTEGRAL MEMBRANE PROTEIN 12 LEPOC|Ensembl=ENSLOCG00000017204.1|UniProtKB=W5NKW1 W5NKW1 PTHR13769:SF1 APOLIPOPROTEIN B APOLIPOPROTEIN B-100 signaling receptor binding#GO:0005102;binding#GO:0005488;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipoprotein particle receptor binding#GO:0070325;lipid transfer activity#GO:0120013;protein binding#GO:0005515;sterol transfer activity#GO:0120015;transporter activity#GO:0005215;cholesterol transfer activity#GO:0120020 lipid transport#GO:0006869;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;sterol transport#GO:0015918;cholesterol homeostasis#GO:0042632;establishment of localization#GO:0051234;neutral lipid metabolic process#GO:0006638;intracellular protein localization#GO:0008104;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;triglyceride metabolic process#GO:0006641;transport#GO:0006810;glycerolipid metabolic process#GO:0046486;homeostatic process#GO:0042592;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;localization#GO:0051179;protein transport#GO:0015031;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;very-low-density lipoprotein particle#GO:0034361;plasma lipoprotein particle#GO:0034358;lipoprotein particle#GO:1990777;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994 apolipoprotein#PC00052;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000002771.1|UniProtKB=W5M4F5 W5M4F5 PTHR15729:SF3 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 31 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;cell leading edge#GO:0031252 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015908.1|UniProtKB=W5NG29 W5NG29 PTHR10574:SF279 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-4 cell motility#GO:0048870;system development#GO:0048731;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;tissue development#GO:0009888;extracellular matrix assembly#GO:0085029;cell migration#GO:0016477;axon development#GO:0061564;axon guidance#GO:0007411;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular component assembly#GO:0022607;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;substrate adhesion-dependent cell spreading#GO:0034446 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;basement membrane#GO:0005604;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000006390.1|UniProtKB=W5MH55 W5MH55 PTHR14963:SF4 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 40 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of biological quality#GO:0065008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of actin filament length#GO:0030832 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000012673.1|UniProtKB=W5N4N7 W5N4N7 PTHR46469:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591 General transcription by RNA polymerase I#P00022>TAF-IB#P00650;General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>TAF-IC#P00649;General transcription regulation#P00023>TBP-associated factors#P00658;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 LEPOC|Ensembl=ENSLOCG00000011975.1|UniProtKB=W5N263 W5N263 PTHR23164:SF30 EARLY ENDOSOME ANTIGEN 1 EARLY ENDOSOME ANTIGEN 1 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 import into cell#GO:0098657;endocytosis#GO:0006897;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010649.1|UniProtKB=W5MXD8 W5MXD8 PTHR12121:SF28 CARBON CATABOLITE REPRESSOR PROTEIN 4 RNA 2',3'-CYCLIC PHOSPHATASE ANGEL1 hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;3'-5'-RNA exonuclease activity#GO:0000175;binding#GO:0005488;mRNA binding#GO:0003729;exonuclease activity#GO:0004527;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;mRNA 3'-UTR binding#GO:0003730;phosphoric ester hydrolase activity#GO:0042578 positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;mitochondrial RNA processing#GO:0000963;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;nucleic acid biosynthetic process#GO:0141187;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;positive regulation of mRNA metabolic process#GO:1903313;nucleobase-containing compound biosynthetic process#GO:0034654;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA processing#GO:0006397;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;RNA 3'-end processing#GO:0031123;regulation of mRNA metabolic process#GO:1903311 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000014380.1|UniProtKB=W5NAP5 W5NAP5 PTHR13119:SF23 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 4 transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription repressor activity#GO:0001217 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription elongation#GO:0032784;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000017275.1|UniProtKB=W5NL59 W5NL59 PTHR15934:SF6 RNA 2',3'-CYCLIC PHOSPHODIESTERASE A-KINASE ANCHOR PROTEIN 7 ISOFORM GAMMA protein binding#GO:0005515;binding#GO:0005488;protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011972.1|UniProtKB=W5N264 W5N264 PTHR48207:SF3 SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE SUCCINYL-COA:GLUTARATE COA-TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 Carnitine metabolism#P02733>Carnitine dehydratase#P02866;Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864 LEPOC|Ensembl=ENSLOCG00000011184.1|UniProtKB=W5MZD2 W5MZD2 PTHR46908:SF10 CUBILIN-LIKE PROTEIN TUMOR NECROSIS FACTOR-INDUCIBLE GENE 6 PROTEIN regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013903.1|UniProtKB=W5N938 W5N938 PTHR15360:SF1 PLATELET-DERIVED GROWTH FACTOR RECEPTOR LIKE PLATELET-DERIVED GROWTH FACTOR RECEPTOR-LIKE PROTEIN tyrosine protein kinase receptor#PC00233 PDGF signaling pathway#P00047>PDGF receptor A#P01158;PDGF signaling pathway#P00047>PDGF receptor B#P01156 LEPOC|Ensembl=ENSLOCG00000004371.1|UniProtKB=W5MA11 W5MA11 PTHR24404:SF1 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 821 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010835.1|UniProtKB=W5MY87 W5MY87 PTHR24023:SF568 COLLAGEN ALPHA COLLAGEN ALPHA-2(I) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular component organization#GO:0016043;cellular process#GO:0009987;multicellular organismal process#GO:0032501;skin development#GO:0043588;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;external encapsulating structure organization#GO:0045229 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000002628.1|UniProtKB=W5M3Z7 W5M3Z7 PTHR14094:SF9 SIGNAL RECOGNITION PARTICLE 72 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72 ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;nucleic acid binding#GO:0003676;binding#GO:0005488 establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;cellular localization#GO:0051641;establishment of localization#GO:0051234;protein targeting to ER#GO:0045047 ribonucleoprotein complex#GO:1990904;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000008496.1|UniProtKB=W5MPN1 W5MPN1 PTHR33538:SF1 PROTEIN GAMETE EXPRESSED 1 PROTEIN BRAMBLEBERRY organelle fission#GO:0048285;sexual reproduction#GO:0019953;nuclear division#GO:0000280;reproductive process#GO:0022414;fertilization#GO:0009566;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;membrane assembly#GO:0071709;cellular component organization#GO:0016043;cell cycle#GO:0007049;nuclear envelope organization#GO:0006998;mitotic cell cycle process#GO:1903047;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;single fertilization#GO:0007338;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 LEPOC|Ensembl=ENSLOCG00000006798.1|UniProtKB=W5MIK4 W5MIK4 PTHR11954:SF49 D-DOPACHROME DECARBOXYLASE MACROPHAGE MIGRATION INHIBITORY FACTOR catalytic activity#GO:0003824;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;isomerase activity#GO:0016853;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;intramolecular oxidoreductase activity#GO:0016860;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;lyase#PC00144;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008706.1|UniProtKB=W5MQD5 W5MQD5 PTHR11886:SF91 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN-RELATED protein binding#GO:0005515;binding#GO:0005488 microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cilium assembly#GO:0060271;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;dynein complex#GO:0030286;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000011607.1|UniProtKB=W5N0W0 W5N0W0 PTHR43160:SF3 ACONITATE HYDRATASE B ACONITATE HYDRATASE, MITOCHONDRIAL catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;iron-sulfur cluster binding#GO:0051536 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 lyase#PC00144;hydratase#PC00120 TCA cycle#P00051>Aconitase#P01268 LEPOC|Ensembl=ENSLOCG00000002556.1|UniProtKB=W5M3S0 W5M3S0 PTHR24149:SF14 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000007223.1|UniProtKB=W5MK30 W5MK30 PTHR14098:SF19 SH2 DOMAIN CONTAINING PROTEIN B-CELL LINKER PROTEIN-RELATED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 B cell activation#P00010>BLNK#P00394 LEPOC|Ensembl=ENSLOCG00000015762.1|UniProtKB=W5NFJ5 W5NFJ5 PTHR46949:SF3 LEUCINE REPEAT ADAPTER PROTEIN 25 PROTEIN FAM89A scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003141.1|UniProtKB=W5M5U0 W5M5U0 PTHR34399:SF3 AVIDIN-RELATED AVIDIN-RELATED organic acid binding#GO:0043177;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363 LEPOC|Ensembl=ENSLOCG00000002846.1|UniProtKB=W5M4N9 W5M4N9 PTHR23050:SF549 CALCIUM BINDING PROTEIN AT22559P cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle assembly#GO:0070925;centriole replication#GO:0007099;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402 centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000014623.1|UniProtKB=W5NBJ2 W5NBJ2 PTHR11353:SF84 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000017169.1|UniProtKB=W5NKR3 W5NKR3 PTHR23351:SF25 FOS TRANSCRIPTION FACTOR-RELATED FOS-RELATED ANTIGEN 2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000017688.1|UniProtKB=W5NMD4 W5NMD4 PTHR40472:SF8 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 2 LEPOC|Ensembl=ENSLOCG00000002637.1|UniProtKB=W5M401 W5M401 PTHR11039:SF37 NEBULIN NEBULIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cardiac muscle cell differentiation#GO:0055007;cytoskeleton organization#GO:0007010;heart development#GO:0007507;cellular component assembly#GO:0022607;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell development#GO:0048468;actomyosin structure organization#GO:0031032;circulatory system development#GO:0072359;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;actin filament organization#GO:0007015;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;system development#GO:0048731;anatomical structure development#GO:0048856 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;I band#GO:0031674;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;Z disc#GO:0030018;contractile muscle fiber#GO:0043292 LEPOC|Ensembl=ENSLOCG00000002696.1|UniProtKB=W5M459 W5M459 PTHR45632:SF14 LD33804P KELCH-LIKE PROTEIN 33 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014466.1|UniProtKB=W5NAZ8 W5NAZ8 PTHR22624:SF35 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4A hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197 catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;autophagosome assembly#GO:0000045;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000004748.1|UniProtKB=W5MBD8 W5MBD8 PTHR15157:SF5 UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN phosphatidylinositol phosphate biosynthetic process#GO:0046854;process utilizing autophagic mechanism#GO:0061919;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;autophagy#GO:0006914;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;macroautophagy#GO:0016236;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610 transferase complex#GO:1990234;extrinsic component of membrane#GO:0019898;lytic vacuole#GO:0000323;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;phosphatidylinositol 3-kinase complex, class III#GO:0035032;endosome#GO:0005768;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011468.1|UniProtKB=W5N0D3 W5N0D3 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200 cellular process#GO:0009987;monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;carbohydrate kinase#PC00065;kinase#PC00137;metabolite interconversion enzyme#PC00262 Fructose galactose metabolism#P02744>Galactokinase#P02960 LEPOC|Ensembl=ENSLOCG00000001035.1|UniProtKB=W5LYE9 W5LYE9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000011217.1|UniProtKB=W5MZH5 W5MZH5 PTHR22996:SF1 MAHOGUNIN E3 UBIQUITIN LIGASE RNF157 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004647.1|UniProtKB=W5MB04 W5MB04 PTHR17384:SF7 P-SELECTIN GLYCOPROTEIN LIGAND-1 P-SELECTIN GLYCOPROTEIN LIGAND 1 leukocyte migration#GO:0050900;immune system process#GO:0002376;cell adhesion#GO:0007155;cell motility#GO:0048870;cell migration#GO:0016477;cell-cell adhesion#GO:0098609;leukocyte cell-cell adhesion#GO:0007159;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004743.1|UniProtKB=W5MBD4 W5MBD4 PTHR42693:SF47 ARYLSULFATASE FAMILY MEMBER N-ACETYLGALACTOSAMINE-6-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005873.1|UniProtKB=W5MFD7 W5MFD7 PTHR24418:SF245 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE HCK transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230 LEPOC|Ensembl=ENSLOCG00000011391.1|UniProtKB=W5N048 W5N048 PTHR13763:SF11 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN ubiquitin-protein transferase activity#GO:0004842;DNA binding#GO:0003677;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;nucleic acid binding#GO:0003676;binding#GO:0005488;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;damaged DNA binding#GO:0003684;transferase activity#GO:0016740;catalytic activity#GO:0003824 double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;recombinational repair#GO:0000725;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049 transferase complex#GO:1990234;condensed chromosome#GO:0000793;intracellular protein-containing complex#GO:0140535;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;DNA repair complex#GO:1990391;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016463.1|UniProtKB=W5NI80 W5NI80 PTHR13768:SF12 SOLUBLE NSF ATTACHMENT PROTEIN SNAP BETA-SOLUBLE NSF ATTACHMENT PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;protein-containing complex disassembly#GO:0032984;chemical synaptic transmission#GO:0007268;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;intracellular protein transport#GO:0006886;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular localization#GO:0051641;cellular component disassembly#GO:0022411;protein transport#GO:0015031 axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;synapse#GO:0045202;SNARE complex#GO:0031201;cell projection#GO:0042995;neuron projection terminus#GO:0044306;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell junction#GO:0030054;axon terminus#GO:0043679;membrane#GO:0016020;presynapse#GO:0098793;neuron projection#GO:0043005;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004260.1|UniProtKB=W5M9N6 W5M9N6 PTHR45664:SF12 PROTEIN ZERKNUELLT 1-RELATED PANCREAS_DUODENUM HOMEOBOX PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 cellular developmental process#GO:0048869;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;pancreas development#GO:0031016;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000012009.1|UniProtKB=W5N2C4 W5N2C4 PTHR24416:SF49 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;vascular endothelial growth factor receptor signaling pathway#GO:0048010;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;angiogenesis#GO:0001525;positive regulation of signaling#GO:0023056;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;tube development#GO:0035295;regulation of locomotion#GO:0040012;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of locomotion#GO:0040017 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VEGFR-2#P00222;VEGF signaling pathway#P00056>VEGFR-2#P01403 LEPOC|Ensembl=ENSLOCG00000003399.1|UniProtKB=W5M6L6 W5M6L6 PTHR10989:SF17 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN-DEPENDENT TFPI-REGULATING PROTEIN catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152 plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;membrane raft#GO:0045121;caveola#GO:0005901 LEPOC|Ensembl=ENSLOCG00000006990.1|UniProtKB=W5MJ98 W5MJ98 PTHR20968:SF2 ILGF DOMAIN-CONTAINING PROTEIN INSULIN-LIKE PEPTIDE INSL5 molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 LEPOC|Ensembl=ENSLOCG00000001956.1|UniProtKB=W5M1K6 W5M1K6 PTHR13313:SF0 CYTOCHROME C OXIDASE SUBUNIT VIIC CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000012767.1|UniProtKB=W5N508 W5N508 PTHR12881:SF13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297;binding#GO:0005488;transcription regulator activity#GO:0140110 cellular response to chemical stimulus#GO:0070887;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;response to hormone#GO:0009725;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000001527.1|UniProtKB=W5M039 W5M039 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000392.1|UniProtKB=W5LWC1 W5LWC1 PTHR23192:SF34 OLFACTOMEDIN-RELATED NOELIN cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016368.1|UniProtKB=W5NHV0 W5NHV0 PTHR11574:SF0 KIT LIGAND KIT LIGAND positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000012344.1|UniProtKB=W5N3K0 W5N3K0 PTHR24166:SF21 ROLLING PEBBLES, ISOFORM B PROTEIN TANC2 structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 regulation of cell projection organization#GO:0031344;regulation of synapse organization#GO:0050807;regulation of dendritic spine morphogenesis#GO:0061001;regulation of synapse structure or activity#GO:0050803;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biological quality#GO:0065008;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;regulation of neuron projection development#GO:0010975;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of developmental process#GO:0050793 somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection#GO:0043005;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015562.1|UniProtKB=W5NEV1 W5NEV1 PTHR43195:SF4 TRANSKETOLASE TRANSKETOLASE-LIKE PROTEIN 2 ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;transketolase activity#GO:0004802;cation binding#GO:0043169;catalytic activity#GO:0003824;transferase activity#GO:0016740;transketolase or transaldolase activity#GO:0016744;heterocyclic compound binding#GO:1901363 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transketolase#PC00221 LEPOC|Ensembl=ENSLOCG00000016739.1|UniProtKB=W5NJ78 W5NJ78 PTHR24393:SF151 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 956 transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000005038.1|UniProtKB=W5MCG0 W5MCG0 PTHR13278:SF0 ZINC FINGER PROTEIN 830 ZINC FINGER PROTEIN 830 regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cell cycle G2/M phase transition#GO:1902750;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;mitotic DNA replication checkpoint signaling#GO:0033314;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;mitotic cell cycle process#GO:1903047;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000006207.1|UniProtKB=W5MGJ0 W5MGJ0 PTHR11132:SF521 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E2A-RELATED active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000013338.1|UniProtKB=W5N738 W5N738 PTHR43977:SF2 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN LEPOC|Ensembl=ENSLOCG00000016101.1|UniProtKB=W5NGU3 W5NGU3 PTHR24006:SF827 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34 cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002294.1|UniProtKB=W5M2W5 W5M2W5 PTHR24416:SF643 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular response to nerve growth factor stimulus#GO:1990090;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;signaling#GO:0023052 axon#GO:0030424;signaling receptor complex#GO:0043235;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017870.1|UniProtKB=W5NMW4 W5NMW4 PTHR24399:SF14 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 26 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cytokine production#GO:0001817;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008637.1|UniProtKB=W5MQ42 W5MQ42 PTHR11818:SF12 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B1 structural molecule activity#GO:0005198 sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008321.1|UniProtKB=W5MP02 W5MP02 PTHR11669:SF1 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 3 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 LEPOC|Ensembl=ENSLOCG00000002794.1|UniProtKB=W5M4H7 W5M4H7 PTHR10204:SF34 NAD P H OXIDOREDUCTASE-RELATED NAD(P)H DEHYDROGENASE [QUINONE] 1 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007436.1|UniProtKB=W5MKW2 W5MKW2 PTHR12889:SF7 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cell communication#GO:0007154;protein metabolic process#GO:0019538;proteolysis#GO:0006508;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;signal transduction#GO:0007165;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012332.1|UniProtKB=W5N3G8 W5N3G8 PTHR15117:SF5 ATAXIN 7 RELATED ATAXIN-7-LIKE PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 LEPOC|Ensembl=ENSLOCG00000003545.1|UniProtKB=W5M731 W5M731 PTHR23085:SF7 GH28348P JUNCTOPHILIN-3 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000008385.1|UniProtKB=W5MP86 W5MP86 PTHR18966:SF108 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, DELTA-1 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987 protein-containing complex#GO:0032991;neuron projection#GO:0043005;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;neuron spine#GO:0044309;cell projection#GO:0042995;postsynapse#GO:0098794;dendritic spine#GO:0043197;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012131.1|UniProtKB=W5N2Q9 W5N2Q9 PTHR45712:SF4 AGAP008170-PA FIBROMODULIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003161.1|UniProtKB=W5M5S5 W5M5S5 PTHR24366:SF170 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS ELRR (EXTRACELLULAR LEUCINE-RICH REPEAT) ONLY immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000004812.1|UniProtKB=W5MBM0 W5MBM0 PTHR12411:SF1075 CYSTEINE PROTEASE FAMILY C1-RELATED COUNTING FACTOR ASSOCIATED PROTEIN D catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000005429.1|UniProtKB=W5MDT6 W5MDT6 PTHR16515:SF20 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 12 protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012058.1|UniProtKB=W5N2H4 W5N2H4 PTHR23240:SF6 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED DNA CROSS-LINK REPAIR 1A PROTEIN catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity#GO:0004529;damaged DNA binding#GO:0003684;DNA binding#GO:0003677;hydrolase activity#GO:0016787;5'-3' exonuclease activity#GO:0008409;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008180.1|UniProtKB=W5MNJ1 W5MNJ1 PTHR12195:SF4 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN 1 multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of protein metabolic process#GO:0051246;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;cell projection assembly#GO:0030031;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;lamellipodium assembly#GO:0030032;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;post-transcriptional regulation of gene expression#GO:0010608;plasma membrane bounded cell projection assembly#GO:0120031;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;axon guidance#GO:0007411;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 neuron projection#GO:0043005;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 LEPOC|Ensembl=ENSLOCG00000017775.1|UniProtKB=W5NMM0 W5NMM0 PTHR24232:SF1 G-PROTEIN COUPLED RECEPTOR N-ARACHIDONYL GLYCINE RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005207.1|UniProtKB=W5MD10 W5MD10 PTHR24418:SF23 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRMS catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715 regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000013978.1|UniProtKB=W5N9B9 W5N9B9 PTHR21281:SF1 CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 cilium movement#GO:0003341;cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 LEPOC|Ensembl=ENSLOCG00000010462.1|UniProtKB=W5MWR2 W5MWR2 PTHR38564:SF2 SI:CH73-250A16.5-RELATED IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013519.1|UniProtKB=W5N7R3 W5N7R3 PTHR19265:SF0 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cilium#GO:0005929;motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010965.1|UniProtKB=W5MYJ6 W5MYJ6 PTHR45697:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003179.1|UniProtKB=W5M5U7 W5M5U7 PTHR12173:SF3 GDNF SUBFAMILY OF TGF-BETA FAMILY NEURTURIN signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 generation of neurons#GO:0048699;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 neurotrophic factor#PC00163;growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007230.1|UniProtKB=W5MK38 W5MK38 PTHR24067:SF263 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G1 catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012805.1|UniProtKB=W5N549 W5N549 PTHR10722:SF0 60S RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN EL19 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000016303.1|UniProtKB=W5NHL3 W5NHL3 PTHR14063:SF4 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of growth#GO:0040008;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;regulation of synapse structure or activity#GO:0050803;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;regulation of cell junction assembly#GO:1901888;regulation of synapse assembly#GO:0051963;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;vesicle localization#GO:0051648;establishment of localization#GO:0051234;transport#GO:0006810;regulation of cellular component organization#GO:0051128;establishment of organelle localization#GO:0051656;export from cell#GO:0140352;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of biological process#GO:0050789;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of biological quality#GO:0065008;regulation of synapse organization#GO:0050807;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic vesicle transport#GO:0048489;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;basal part of cell#GO:0045178;membrane protein complex#GO:0098796;adherens junction#GO:0005912;cell junction#GO:0030054;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cell-cell junction#GO:0005911;membrane#GO:0016020;basolateral plasma membrane#GO:0016323 cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000012513.1|UniProtKB=W5N444 W5N444 PTHR11505:SF204 L1 TRANSPOSABLE ELEMENT-RELATED L1 TRANSPOSABLE ELEMENT RRM DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000007916.1|UniProtKB=W5MML1 W5MML1 HOOK2 PTHR18947:SF37 HOOK PROTEINS PROTEIN HOOK HOMOLOG 2 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cytoplasmic microtubule organization#GO:0031122 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017938.1|UniProtKB=W5NN32 W5NN32 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014073.1|UniProtKB=W5N9N7 W5N9N7 PTHR12369:SF42 CHONDROITIN SYNTHASE CHONDROITIN SULFATE SYNTHASE 1 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000002625.1|UniProtKB=W5M3Y8 W5M3Y8 PTHR13713:SF95 SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 4 sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016487.1|UniProtKB=W5NIA6 W5NIA6 PTHR24201:SF15 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 66 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000004526.1|UniProtKB=W5MAL3 W5MAL3 PTHR43557:SF7 APOPTOSIS-INDUCING FACTOR 1 RIESKE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016102.1|UniProtKB=W5NGS9 W5NGS9 PTHR45752:SF169 LEUCINE-RICH REPEAT-CONTAINING NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006063.1|UniProtKB=W5MG12 W5MG12 PTHR15678:SF6 ANTIGEN MLAA-22-RELATED BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2 LEPOC|Ensembl=ENSLOCG00000015677.1|UniProtKB=W5NF90 W5NF90 PTHR10338:SF14 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H2 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000006601.1|UniProtKB=W5MHW8 W5MHW8 PTHR24099:SF4 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 regulation of microtubule-based process#GO:0032886;regulation of cell division#GO:0051302;regulation of mitotic spindle organization#GO:0060236;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of spindle organization#GO:0090224;regulation of cellular process#GO:0050794 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009908.1|UniProtKB=W5MUQ6 W5MUQ6 PTHR11547:SF23 ARGININE OR CREATINE KINASE CREATINE KINASE B-TYPE phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;amino acid kinase#PC00045 LEPOC|Ensembl=ENSLOCG00000017579.1|UniProtKB=W5NM25 W5NM25 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H6 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015380.1|UniProtKB=W5NE70 W5NE70 PTHR22599:SF30 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 1A protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;hippo signaling#GO:0035329;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase activator#PC00138 CCKR signaling map#P06959>MOB1#G07283;CCKR signaling map#P06959>MOB1#G06990 LEPOC|Ensembl=ENSLOCG00000013122.1|UniProtKB=W5N6A5 W5N6A5 PTHR25465:SF10 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF-CONTAINING PROTEIN 16 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008684.1|UniProtKB=W5MQA3 W5MQA3 PTHR23329:SF1 TUFTELIN-INTERACTING PROTEIN 11-RELATED TUFTELIN-INTERACTING PROTEIN 11 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;protein-containing complex disassembly#GO:0032984 U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000016715.1|UniProtKB=W5NJ47 W5NJ47 PTHR43762:SF8 L-GULONOLACTONE OXIDASE L-GULONOLACTONE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 monosaccharide metabolic process#GO:0005996;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;L-ascorbic acid metabolic process#GO:0019852;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975 oxidoreductase#PC00176;oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007528.1|UniProtKB=W5ML71 W5ML71 PTHR15186:SF4 RE48077P BCL2_ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;organelle organization#GO:0006996;reticulophagy#GO:0061709;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;autophagy#GO:0006914;cellular process#GO:0009987;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;apoptotic mitochondrial changes#GO:0008637;macroautophagy#GO:0016236;process utilizing autophagic mechanism#GO:0061919;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000000495.1|UniProtKB=W5LWN7 W5LWN7 PTHR32094:SF5 FANCONI ANEMIA GROUP E PROTEIN FANCONI ANEMIA GROUP E PROTEIN Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000018282.1|UniProtKB=W5NP24 W5NP24 PTHR24233:SF6 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PLATELET-ACTIVATING FACTOR RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000002105.1|UniProtKB=W5M232 W5M232 PTHR31609:SF1 YDJC DEACETYLASE FAMILY MEMBER CARBOHYDRATE DEACETYLASE deacetylase activity#GO:0019213;deacylase activity#GO:0160215;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000017033.1|UniProtKB=W5NK95 W5NK95 PTHR42765:SF3 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;translation#GO:0006412 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000009249.1|UniProtKB=W5MSD9 W5MSD9 PTHR46022:SF5 PROTEIN PATCHED PROTEIN PATCHED HOMOLOG 1 binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 Hedgehog signaling pathway#P00025>Patched#P00689 LEPOC|Ensembl=ENSLOCG00000000591.1|UniProtKB=W5LWZ6 W5LWZ6 PTHR19971:SF24 SIGNAL-REGULATORY PROTEIN BETA IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005532.1|UniProtKB=W5ME89 W5ME89 PTHR10407:SF10 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN-INTERACTING PROTEIN 1-RELATED PROTEIN protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal adaptor activity#GO:0008093;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090 regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;actin filament organization#GO:0007015;establishment of localization#GO:0051234;transport#GO:0006810;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;positive regulation of cell communication#GO:0010647;regulation of ERBB signaling pathway#GO:1901184;positive regulation of signal transduction#GO:0009967;supramolecular fiber organization#GO:0097435;localization#GO:0051179;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051 cortical cytoskeleton#GO:0030863;intracellular vesicle#GO:0097708;actin cytoskeleton#GO:0015629;vesicle#GO:0031982;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;clathrin-coated vesicle#GO:0030136;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Huntington disease#P00029>Hip-12#P00763 LEPOC|Ensembl=ENSLOCG00000017947.1|UniProtKB=W5NN41 W5NN41 PTHR46375:SF5 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13-RELATED KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13 LEPOC|Ensembl=ENSLOCG00000015280.1|UniProtKB=W5NDU3 W5NDU3 PTHR14091:SF0 PERIODIC TRYPTOPHAN PROTEIN 1 PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase I#GO:0006356;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase I#GO:0045943;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000002602.1|UniProtKB=W5M3V4 W5M3V4 PTHR24133:SF59 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT AND FYVE DOMAIN CONTAINING 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005727.1|UniProtKB=W5MEV8 W5MEV8 PTHR13376:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036 motile cilium#GO:0031514;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intraciliary transport particle B#GO:0030992 LEPOC|Ensembl=ENSLOCG00000007637.1|UniProtKB=W5MLK8 W5MLK8 PTHR12001:SF89 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 LEPOC|Ensembl=ENSLOCG00000001632.1|UniProtKB=W5M0G9 W5M0G9 PTHR10395:SF11 URICASE AND TRANSTHYRETIN-RELATED 5-HYDROXYISOURATE HYDROLASE nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008010.1|UniProtKB=W5MMX3 W5MMX3 PTHR21228:SF29 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA stability#GO:0043487;mitochondrial RNA metabolic process#GO:0000959;regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488 membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011941.1|UniProtKB=W5N226 W5N226 PTHR11375:SF2 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER B protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012558.1|UniProtKB=W5N4B0 W5N4B0 PTHR45780:SF2 ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000001524.1|UniProtKB=W5M036 W5M036 PTHR12290:SF2 CORNICHON-RELATED PHOSPHOPANTOTHENATE--CYSTEINE LIGASE membrane traffic protein#PC00150 Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882 LEPOC|Ensembl=ENSLOCG00000011349.1|UniProtKB=W5MZZ1 W5MZZ1 PTHR48041:SF82 ABC TRANSPORTER G FAMILY MEMBER 28 ATP BINDING CASSETTE SUBFAMILY G MEMBER 2 ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015198.1|UniProtKB=W5NDJ9 W5NDJ9 PTHR24075:SF5 SEC63 DOMAIN-CONTAINING U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011137.1|UniProtKB=W5MZ82 W5MZ82 PTHR24347:SF384 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of signaling#GO:0023051;regulation of synaptic plasticity#GO:0048167;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008;regulation of neuronal synaptic plasticity#GO:0048168;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;postsynaptic density#GO:0014069;axon#GO:0030424;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;neuron projection#GO:0043005 non-receptor serine/threonine protein kinase#PC00167 Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847 LEPOC|Ensembl=ENSLOCG00000003147.1|UniProtKB=W5M5S0 W5M5S0 PTHR13140:SF289 MYOSIN UNCONVENTIONAL MYOSIN-XIX cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;actin cytoskeleton#GO:0015629 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000010893.1|UniProtKB=W5MY94 W5MY94 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006115.1|UniProtKB=W5MG82 W5MG82 PTHR43191:SF2 RRNA METHYLTRANSFERASE 3, RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002398.1|UniProtKB=W5M357 W5M357 PTHR11267:SF13 T-BOX PROTEIN-RELATED EOMESODERMIN HOMOLOG transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 formation of primary germ layer#GO:0001704;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;cell activation involved in immune response#GO:0002263;cell fate commitment#GO:0045165;mononuclear cell differentiation#GO:1903131;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;gastrulation#GO:0007369;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;cell fate specification#GO:0001708;endoderm development#GO:0007492;anatomical structure formation involved in morphogenesis#GO:0048646;mesoderm development#GO:0007498;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;cellular process#GO:0009987;lymphocyte activation involved in immune response#GO:0002285;embryo development#GO:0009790;endoderm formation#GO:0001706;T cell activation involved in immune response#GO:0002286;T cell differentiation#GO:0030217;lymphocyte activation#GO:0046649;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;mesoderm morphogenesis#GO:0048332;leukocyte activation#GO:0045321;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;immune response#GO:0006955;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;hemopoiesis#GO:0030097;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;tissue development#GO:0009888;regulation of nucleobase-containing compound metabolic process#GO:0019219;mesoderm formation#GO:0001707 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 LEPOC|Ensembl=ENSLOCG00000002178.1|UniProtKB=W5M2C9 W5M2C9 PTHR24229:SF32 NEUROPEPTIDES RECEPTOR G PROTEIN-COUPLED RECEPTOR 149-RELATED binding#GO:0005488;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012216.1|UniProtKB=W5N333 W5N333 PTHR20854:SF26 INOSITOL MONOPHOSPHATASE INOSITOL MONOPHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004694.1|UniProtKB=W5MB68 W5MB68 PTHR23236:SF27 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EMBRYONIC POLYADENYLATE-BINDING PROTEIN 2 poly(A) binding#GO:0008143;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011190.1|UniProtKB=W5MZF5 W5MZF5 PTHR45901:SF3 PROTEIN CBG12474 LIPOXYGENASE HOMOLOGY PLAT DOMAINS 1 LEPOC|Ensembl=ENSLOCG00000014140.1|UniProtKB=W5N9V8 W5N9V8 PTHR19964:SF14 MULTIPLE PDZ DOMAIN PROTEIN E3 UBIQUITIN-PROTEIN LIGASE LNX ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Notch signaling pathway#P00045>LNXp80#P01111 LEPOC|Ensembl=ENSLOCG00000004679.1|UniProtKB=W5MB43 W5MB43 PTHR10104:SF18 STATHMIN STATHMIN-2 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 regulation of microtubule-based process#GO:0032886;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;system development#GO:0048731;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;protein-containing complex disassembly#GO:0032984;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;microtubule polymerization or depolymerization#GO:0031109;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;protein depolymerization#GO:0051261;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular component disassembly#GO:0022411;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell development#GO:0048468;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;microtubule depolymerization#GO:0007019;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507 site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;growth cone#GO:0030426;axon#GO:0030424;cytoplasm#GO:0005737;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000014393.1|UniProtKB=W5NAR2 W5NAR2 PTHR24103:SF706 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM39 ISOFORM X1-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007222.1|UniProtKB=W5MK35 W5MK35 PTHR19304:SF9 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;Gonadotropin-releasing hormone receptor pathway#P06664>ATF2#P06732;Oxidative stress response#P00046>ATF2#P01126;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;CCKR signaling map#P06959>ATF2#P07078;Ras Pathway#P04393>ATF2#P04548 LEPOC|Ensembl=ENSLOCG00000004417.1|UniProtKB=W5MA70 W5MA70 PTHR24264:SF86 TRYPSIN-RELATED TRYPSIN-3 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000011909.1|UniProtKB=W5N1Y3 W5N1Y3 PTHR16866:SF2 GASTRIN-RELEASING PEPTIDE GASTRIN-RELEASING PEPTIDE regulation of response to stress#GO:0080134;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 LEPOC|Ensembl=ENSLOCG00000005026.1|UniProtKB=W5MCE1 W5MCE1 PTHR12366:SF33 ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE ASPARTYL_ASPARAGINYL BETA-HYDROXYLASE 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008334.1|UniProtKB=W5MP12 W5MP12 PTHR13069:SF35 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 TRNA METHYLTRANSFERASE 9B-RELATED RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA binding#GO:0000049;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723;methyltransferase activity#GO:0008168;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000017003.1|UniProtKB=W5NK70 W5NK70 PTHR10537:SF3 DNA PRIMASE LARGE SUBUNIT DNA PRIMASE LARGE SUBUNIT cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA replication initiation#GO:0006270;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;DNA-templated DNA replication#GO:0006261 transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;nuclear DNA-directed RNA polymerase complex#GO:0055029;replisome#GO:0030894;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-DNA complex#GO:0032993;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 primase#PC00189 DNA replication#P00017>Primase#P00528 LEPOC|Ensembl=ENSLOCG00000014482.1|UniProtKB=W5NB30 W5NB30 PTHR10338:SF115 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H3 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000010685.1|UniProtKB=W5MXH8 W5MXH8 PTHR19433:SF111 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 4 response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014419.1|UniProtKB=W5NAU1 W5NAU1 PTHR45752:SF5 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 28 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004249.1|UniProtKB=W5M9L9 W5M9L9 AK6 PTHR12595:SF0 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776;binding#GO:0005488;nucleobase-containing compound kinase activity#GO:0019205;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;kinase activity#GO:0016301 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001495.1|UniProtKB=W5M004 W5M004 PTHR22028:SF4 SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN SFI1 HOMOLOG protein binding#GO:0005515;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899 LEPOC|Ensembl=ENSLOCG00000001792.1|UniProtKB=W5M118 W5M118 PTHR42738:SF18 HYDROXYMETHYLGLUTARYL-COA LYASE HYDROXYMETHYLGLUTARYL-COA LYASE catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;lipid biosynthetic process#GO:0008610;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000010631.1|UniProtKB=W5MXA8 W5MXA8 PTHR45625:SF6 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG catalytic activity#GO:0003824;cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016735.1|UniProtKB=W5NJ75 W5NJ75 PTHR12431:SF16 SORTING NEXIN 17 AND 27 SORTING NEXIN-17 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;localization#GO:0051179;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;cellular localization#GO:0051641 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014349.1|UniProtKB=W5NAL0 W5NAL0 PTHR13596:SF0 SMALL EDRK-RICH FACTOR 1 SI:CH211-39K3.2-RELATED LEPOC|Ensembl=ENSLOCG00000006009.1|UniProtKB=W5MFV0 W5MFV0 PTHR24346:SF51 MAP/MICROTUBULE AFFINITY-REGULATING KINASE PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of carbohydrate metabolic process#GO:0006109;negative regulation of cellular process#GO:0048523;regulation of glycogen biosynthetic process#GO:0005979;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of polysaccharide metabolic process#GO:0032881;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of carbohydrate biosynthetic process#GO:0043255;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014927.1|UniProtKB=W5NCM1 W5NCM1 PTHR47979:SF69 DRAB11-RELATED RAS-RELATED PROTEIN RAB-39B purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;ribonucleotide binding#GO:0032553;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;myosin binding#GO:0017022;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 transport#GO:0006810;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017244.1|UniProtKB=W5NL19 W5NL19 PTHR12874:SF9 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 48 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000001229.1|UniProtKB=W5LZ34 W5LZ34 PTHR47231:SF1 UPF0722 PROTEIN C11ORF88 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN HOATZ LEPOC|Ensembl=ENSLOCG00000002698.1|UniProtKB=W5M464 W5M464 PTHR10024:SF175 SYNAPTOTAGMIN C2 DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;binding#GO:0005488;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 vesicle-mediated transport#GO:0016192;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of localization#GO:0032879;regulation of transport#GO:0051049;transport#GO:0006810;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;trans-synaptic signaling#GO:0099537 plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000002662.1|UniProtKB=W5M423 W5M423 PTHR44699:SF1 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015312.1|UniProtKB=W5NDY4 W5NDY4 PTHR19443:SF4 HEXOKINASE HEXOKINASE-2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;intracellular chemical homeostasis#GO:0055082;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;oxoacid metabolic process#GO:0043436;intracellular glucose homeostasis#GO:0001678;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;carbohydrate homeostasis#GO:0033500;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;ADP metabolic process#GO:0046031;cellular homeostasis#GO:0019725;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;ADP catabolic process#GO:0046032;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;glucose homeostasis#GO:0042593;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;pyruvate metabolic process#GO:0006090 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic side of membrane#GO:0098562;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966;Glycolysis#P00024>Hexokinase#P00677 LEPOC|Ensembl=ENSLOCG00000013261.1|UniProtKB=W5N6T9 W5N6T9 PTHR21292:SF13 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903 cytoplasm#GO:0005737;exocyst#GO:0000145;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001466.1|UniProtKB=W5LZX4 W5LZX4 PTHR19957:SF84 SYNTAXIN SYNTAXIN-1A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 secretion by cell#GO:0032940;protein transport#GO:0015031;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;vesicle fusion#GO:0006906;export from cell#GO:0140352;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;exocytosis#GO:0006887;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane fusion#GO:0061025 cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091 LEPOC|Ensembl=ENSLOCG00000014980.1|UniProtKB=W5NCT2 W5NCT2 PTHR11937:SF195 ACTIN BETA-CENTRACTIN structural molecule activity#GO:0005198;protein-membrane adaptor activity#GO:0043495;cytoskeletal adaptor activity#GO:0008093;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;structural constituent of cytoskeleton#GO:0005200 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;nuclear migration#GO:0007097;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;cellular localization#GO:0051641;localization#GO:0051179 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 LEPOC|Ensembl=ENSLOCG00000002029.1|UniProtKB=W5M1V0 W5M1V0 PTHR48013:SF21 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 3 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>MKK3#P01367;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891;Apoptosis signaling pathway#P00006>MKK3#P00314;EGF receptor signaling pathway#P00018>MKK3,6#P00540;Integrin signalling pathway#P00034>MEK#P00925;Ras Pathway#P04393>MKK3/6#P04568;FGF signaling pathway#P00021>MKK3,6#P00625;Gonadotropin-releasing hormone receptor pathway#P06664>MKK3/6#P06805;p38 MAPK pathway#P05918>MKK3#P06036;Oxidative stress response#P00046>MKK3/6#P01121 LEPOC|Ensembl=ENSLOCG00000018037.1|UniProtKB=W5NNC9 W5NNC9 PTHR26451:SF854 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003845.1|UniProtKB=W5M882 W5M882 PTHR31594:SF11 AIG1-TYPE G DOMAIN-CONTAINING PROTEIN CYTOLYTIC TOXIN-ALPHA ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000000762.1|UniProtKB=W5LXJ1 W5LXJ1 PTHR10030:SF45 ALPHA-L-FUCOSIDASE PLASMA ALPHA-L-FUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 hydrolase#PC00121;glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000011562.1|UniProtKB=W5N0Q5 W5N0Q5 PTHR31220:SF4 HYCCIN RELATED HYCCIN protein localization to membrane#GO:0072657;phosphorus metabolic process#GO:0006793;protein localization to plasma membrane#GO:0072659;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;localization within membrane#GO:0051668;phosphatidylinositol phosphate biosynthetic process#GO:0046854;localization#GO:0051179;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009473.1|UniProtKB=W5MT67 W5MT67 PTHR16036:SF2 ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 TRNA ENDONUCLEASE ANKZF1 RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;translational elongation#GO:0006414;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;rescue of stalled cytosolic ribosome#GO:0072344;protein biosynthetic process#GO:0160307;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cytoplasmic translation#GO:0002181;translation#GO:0006412;protein catabolic process#GO:0030163;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000016639.1|UniProtKB=W5NIU6 W5NIU6 PTHR11081:SF8 FLAP ENDONUCLEASE FAMILY MEMBER EXONUCLEASE 1 hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 LEPOC|Ensembl=ENSLOCG00000001329.1|UniProtKB=W5LZF5 W5LZF5 PTHR15751:SF11 TRAFFICKING KINESIN-BINDING PROTEIN TRAFFICKING KINESIN-BINDING PROTEIN 1 GABA receptor binding#GO:0050811;signaling receptor binding#GO:0005102;binding#GO:0005488;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 microtubule-based transport#GO:0099111;lysosomal transport#GO:0007041;animal gross anatomical part developmental process#GO:0160108;cellular localization#GO:0051641;cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656;protein targeting#GO:0006605;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of vesicle localization#GO:0051650;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;vesicle-mediated transport#GO:0016192;endosome to lysosome transport#GO:0008333;organelle localization#GO:0051640;system development#GO:0048731;localization#GO:0051179;anatomical structure development#GO:0048856;microtubule-based movement#GO:0007018;developmental process#GO:0032502;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;vesicle cytoskeletal trafficking#GO:0099518;mitochondrion localization#GO:0051646;neurogenesis#GO:0022008;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501 neuron projection#GO:0043005;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;mitochondrion#GO:0005739;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;dendrite#GO:0030425;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016385.1|UniProtKB=W5NHY0 W5NHY0 PTHR13146:SF0 SOLUTE CARRIER FAMILY 35 MEMBER F6-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F6 membrane#GO:0016020;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005052.1|UniProtKB=W5MCH0 W5MCH0 PTHR36129:SF2 ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA-RELATED RICIN B LECTIN DOMAIN-CONTAINING PROTEIN transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001720.1|UniProtKB=W5M0S9 W5M0S9 PTHR46756:SF14 TRANSGELIN GAS2-LIKE PROTEIN 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;actin filament organization#GO:0007015;intracellular protein localization#GO:0008104;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;protein localization to microtubule cytoskeleton#GO:0072698;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule-based process#GO:0032886;actin filament-based process#GO:0030029;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;supramolecular fiber organization#GO:0097435;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;protein localization to organelle#GO:0033365;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493 cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;microtubule end#GO:1990752;actin filament bundle#GO:0032432;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;actomyosin#GO:0042641;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;stress fiber#GO:0001725 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003758.1|UniProtKB=W5M7Y0 W5M7Y0 PTHR10983:SF9 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GAMMA acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000018187.1|UniProtKB=W5NNS9 W5NNS9 PTHR26450:SF44 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51M1 transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011681.1|UniProtKB=W5N148 W5N148 PTHR15902:SF1 NEURITIN-RELATED NEURITIN generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;developmental cell growth#GO:0048588;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;neuron projection morphogenesis#GO:0048812;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental growth#GO:0048589;cell growth#GO:0016049;cellular developmental process#GO:0048869;cellular process#GO:0009987;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000014514.1|UniProtKB=W5NB57 W5NB57 PTHR43272:SF22 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 4 ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;developmental process#GO:0032502;neuron differentiation#GO:0030182 lipid droplet#GO:0005811;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000007953.1|UniProtKB=W5MMR3 W5MMR3 PTHR45742:SF2 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C7 humoral immune response#GO:0006959;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of immune response#GO:0050778;positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune system process#GO:0002376;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;extracellular region#GO:0005576 complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000015996.1|UniProtKB=W5NGD8 W5NGD8 PTHR19143:SF189 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBROLEUKIN extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010503.1|UniProtKB=W5MWW5 W5MWW5 PTHR23192:SF8 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 3 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000015802.1|UniProtKB=W5NFQ4 W5NFQ4 PTHR13743:SF86 BEIGE/BEACH-RELATED LYSOSOMAL-TRAFFICKING REGULATOR cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;cellular component organization#GO:0016043;lysosome organization#GO:0007040;cellular process#GO:0009987;lytic vacuole organization#GO:0080171 lysosome#GO:0005764;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013251.1|UniProtKB=W5N6S5 W5N6S5 PTHR15715:SF22 CENTROSOMAL PROTEIN OF 170 KDA SARCOLEMMAL MEMBRANE-ASSOCIATED PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of membrane potential#GO:0042391;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007759.1|UniProtKB=W5MM13 W5MM13 PTHR16477:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 106 COILED-COIL DOMAIN-CONTAINING PROTEIN 106 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000010176.1|UniProtKB=W5MVP9 W5MVP9 PTHR43903:SF10 NEUROLIGIN NEUROLIGIN-4, Y-LINKED postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017045.1|UniProtKB=W5NKB4 W5NKB4 PTHR12011:SF40 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR B3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 anatomical structure maturation#GO:0071695;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;cell communication#GO:0007154;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cell maturation#GO:0048469;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 cell junction#GO:0030054;extracellular region#GO:0005576;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 p53 pathway#P00059>BAI-1#G04699 LEPOC|Ensembl=ENSLOCG00000003680.1|UniProtKB=W5M7P3 W5M7P3 PTHR21646:SF32 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 33 cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;nervous system development#GO:0007399;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;multicellular organism development#GO:0007275 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000000473.1|UniProtKB=W5LWL2 W5LWL2 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009290.1|UniProtKB=W5MSG9 W5MSG9 PTHR22437:SF1 WINGED HELIX DOMAIN-CONTAINING PROTEIN STORKHEAD-BOX PROTEIN 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000014676.1|UniProtKB=W5NBR1 W5NBR1 PTHR11384:SF21 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1 carboxylic acid transmembrane transporter activity#GO:0046943;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;transmembrane transporter activity#GO:0022857;nucleotide binding#GO:0000166;monocarboxylic acid transmembrane transporter activity#GO:0008028;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 cellular component organization or biogenesis#GO:0071840;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;fatty acid oxidation#GO:0019395;metabolic process#GO:0008152;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;lipid catabolic process#GO:0016042;organelle organization#GO:0006996;fatty acid catabolic process#GO:0009062;cellular localization#GO:0051641;transmembrane transport#GO:0055085;peroxisome organization#GO:0007031;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;small molecule catabolic process#GO:0044282;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;cellular component organization#GO:0016043;monocarboxylic acid metabolic process#GO:0032787;establishment of localization#GO:0051234;lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;transport#GO:0006810;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;intracellular transport#GO:0046907;monocarboxylic acid catabolic process#GO:0072329;lipid transport#GO:0006869;carboxylic acid catabolic process#GO:0046395;macromolecule localization#GO:0033036;peroxisomal transport#GO:0043574;monocarboxylic acid transport#GO:0015718;lipid oxidation#GO:0034440;localization#GO:0051179;fatty acid transport#GO:0015908;carboxylic acid transmembrane transport#GO:1905039;catabolic process#GO:0009056;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000011343.1|UniProtKB=W5MZY7 W5MZY7 PTHR10117:SF9 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 7 monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;binding#GO:0005488 cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;single fertilization#GO:0007338;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;sexual reproduction#GO:0019953;calcium ion homeostasis#GO:0055074;reproductive process#GO:0022414;fertilization#GO:0009566;metal ion transport#GO:0030001;homeostatic process#GO:0042592;regulation of cytosolic calcium ion concentration#GO:0051480;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000009430.1|UniProtKB=W5MSZ6 W5MSZ6 PTHR34491:SF156 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED AUGMIN COMPLEX SUBUNIT DGT5 LEPOC|Ensembl=ENSLOCG00000001482.1|UniProtKB=W5LZY9 W5LZY9 PTHR12984:SF15 SCY1-RELATED S/T PROTEIN KINASE-LIKE PROTEIN-ASSOCIATING WITH THE CARBOXYL-TERMINAL DOMAIN OF EZRIN non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000003113.1|UniProtKB=W5M5K4 W5M5K4 PTHR45869:SF2 C-REACTIVE PROTEIN-RELATED C-REACTIVE PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000003838.1|UniProtKB=W5M879 W5M879 PTHR11267:SF169 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR T-A RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 tissue development#GO:0009888;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;mesoderm formation#GO:0001707;epithelium development#GO:0060429;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;mesoderm morphogenesis#GO:0048332;heart morphogenesis#GO:0003007;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;tissue morphogenesis#GO:0048729;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389;heart development#GO:0007507;embryo development#GO:0009790;cellular process#GO:0009987;mesoderm development#GO:0007498;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;anterior/posterior pattern specification#GO:0009952;cell fate specification#GO:0001708;cell differentiation#GO:0030154;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;gastrulation#GO:0007369;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;formation of primary germ layer#GO:0001704 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000011185.1|UniProtKB=W5MZD0 W5MZD0 PTHR45793:SF2 HOMEOBOX PROTEIN HOMEOBOX PROTEIN OTX2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000001673.1|UniProtKB=W5M0N9 W5M0N9 PTHR45766:SF3 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;cellular process#GO:0009987;response to stress#GO:0006950;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000012018.1|UniProtKB=W5N2C6 W5N2C6 PTHR15228:SF19 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 24 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of small GTPase mediated signal transduction#GO:0051056;morphogenesis of an epithelium#GO:0002009;cellular process#GO:0009987;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;negative regulation of cell communication#GO:0010648;wound healing#GO:0042060;negative regulation of intracellular signal transduction#GO:1902532;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of plasma membrane bounded cell projection organization#GO:0120035;response to wounding#GO:0009611;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;epithelium development#GO:0060429;negative regulation of response to stimulus#GO:0048585;tissue development#GO:0009888;cell migration#GO:0016477;regulation of cell projection assembly#GO:0060491;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;negative regulation of cellular component organization#GO:0051129;regulation of cell communication#GO:0010646;cell motility#GO:0048870;regulation of cellular process#GO:0050794 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;anchoring junction#GO:0070161 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000007963.1|UniProtKB=W5MMR1 W5MMR1 PTHR45944:SF3 SCHNURRI, ISOFORM F ZINC FINGER PROTEIN 40 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001983.1|UniProtKB=W5M1Q0 W5M1Q0 PTHR15138:SF22 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TAFH DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011186.1|UniProtKB=W5MZD9 W5MZD9 PTHR12207:SF3 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN PROSTAGLANDIN F2 RECEPTOR NEGATIVE REGULATOR membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017787.1|UniProtKB=W5NMN2 W5NMN2 PTHR13864:SF10 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED HELIX-LOOP-HELIX PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000010865.1|UniProtKB=W5MY55 W5MY55 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000018342.1|UniProtKB=W5NP84 W5NP84 PTHR46341:SF2 PROTEIN FAM84B-RELATED PROTEIN LRATD2 LEPOC|Ensembl=ENSLOCG00000013467.1|UniProtKB=W5N7K7 W5N7K7 PTHR18896:SF121 PHOSPHOLIPASE D PHOSPHOLIPASE D2 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;lipase activity#GO:0016298;hydrolase activity#GO:0016787 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;regulation of cellular process#GO:0050794;organophosphate catabolic process#GO:0046434;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;regulation of localization#GO:0032879;regulation of transport#GO:0051049 membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 phospholipase#PC00186;lipase#PC00143 Angiogenesis#P00005>PLD#P00204;Parkinson disease#P00049>PLD2#P01207;Ras Pathway#P04393>PLD#P04574 LEPOC|Ensembl=ENSLOCG00000013725.1|UniProtKB=W5N8G2 W5N8G2 PTHR45973:SF9 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 46 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017892.1|UniProtKB=W5NMY6 W5NMY6 PTHR21734:SF10 INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN LEPOC|Ensembl=ENSLOCG00000017292.1|UniProtKB=W5NL88 W5NL88 PTHR45643:SF17 REVERSE TRANSCRIPTASE RIBONUCLEASE H reverse transcriptase#PC00200;viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000006040.1|UniProtKB=W5MFY3 W5MFY3 PTHR19343:SF13 T CELL RECEPTOR ALPHA VARIABLE 1-2 IG-LIKE DOMAIN-CONTAINING PROTEIN peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007255.1|UniProtKB=W5MK71 W5MK71 PTHR19944:SF86 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN protein-containing complex binding#GO:0044877;binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cell activation#GO:0050867;positive regulation of cellular process#GO:0048522;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of leukocyte activation#GO:0002696;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865 vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000015018.1|UniProtKB=W5NCX9 W5NCX9 PTHR10501:SF30 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B RNA BINDING PROTEIN, MRNA PROCESSING FACTOR 2-RELATED RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of biological process#GO:0048519;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;regulation of cell differentiation#GO:0045595;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of developmental process#GO:0050793 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017135.1|UniProtKB=W5NKL7 W5NKL7 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012177.1|UniProtKB=W5N2W3 W5N2W3 PTHR31841:SF1 PROTEIN FAM72A-RELATED PROTEIN FAM72A-RELATED cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000017195.1|UniProtKB=W5NKU5 W5NKU5 PTHR10915:SF5 SYNDECAN SYNDECAN-1 biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of organelle assembly#GO:1902115;positive regulation of biological process#GO:0048518;regulation of organelle organization#GO:0033043;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007948.1|UniProtKB=W5MMQ1 W5MMQ1 PTHR45720:SF3 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN CLC-KB monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic anion channel activity#GO:0008308;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011082.1|UniProtKB=W5MZ05 W5MZ05 PTHR11670:SF32 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER CYTOPLASMIC ACONITATE HYDRATASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;iron-sulfur cluster binding#GO:0051536;lyase activity#GO:0016829;RNA binding#GO:0003723 chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;cellular process#GO:0009987;intracellular monoatomic ion homeostasis#GO:0006873;carboxylic acid metabolic process#GO:0019752;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;small molecule metabolic process#GO:0044281;intracellular iron ion homeostasis#GO:0006879 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 LEPOC|Ensembl=ENSLOCG00000005164.1|UniProtKB=W5MCV9 W5MCV9 PTHR24323:SF8 CEH-10 HOMEODOMAIN-CONTAINING HOMOLOG VISUAL SYSTEM HOMEOBOX 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002113.1|UniProtKB=W5M240 W5M240 PTHR24366:SF154 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS NYCTALOPIN immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000011936.1|UniProtKB=W5N2L6 W5N2L6 PTHR45615:SF69 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-6 isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Wnt signaling pathway#P00057>NFAT Target Genes#G01559 LEPOC|Ensembl=ENSLOCG00000008348.1|UniProtKB=W5MP36 W5MP36 PTHR22100:SF13 WINGS APART-LIKE PROTEIN HOMOLOG WINGS APART-LIKE PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000017699.1|UniProtKB=W5NME5 W5NME5 PTHR24366:SF41 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000006030.1|UniProtKB=W5MG08 W5MG08 PTHR24198:SF199 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY ANKYRIN REPEAT SUBUNIT A ISOFORM X1 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000006726.1|UniProtKB=W5MIA9 W5MIA9 PTHR21527:SF6 NUCLEOPORIN NUP35 NUCLEOPORIN NUP35 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;cellular localization#GO:0051641;nuclear pore organization#GO:0006999;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;nucleus organization#GO:0006997;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;macromolecule localization#GO:0033036;organelle organization#GO:0006996;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011398.1|UniProtKB=W5N054 W5N054 PTHR43836:SF13 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE A catalytic activity#GO:0003824;O-methyltransferase activity#GO:0008171;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056;amine catabolic process#GO:0009310;metabolic process#GO:0008152;catecholamine metabolic process#GO:0006584 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000017612.1|UniProtKB=W5NM58 W5NM58 PTHR45134:SF5 OS08G0543275 PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007597.1|UniProtKB=W5MLF7 W5MLF7 PTHR23292:SF7 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR CELL DEATH-INDUCING P53-TARGET PROTEIN 1 metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;ion binding#GO:0043167;transition metal ion binding#GO:0046914 biological regulation#GO:0065007;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular process#GO:0009987;signal transduction#GO:0007165;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;signaling#GO:0023052;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;cytoplasmic side of membrane#GO:0098562;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vacuole#GO:0005773;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;nucleus#GO:0005634;side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;lysosome#GO:0005764 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017785.1|UniProtKB=W5NMN0 W5NMN0 PTHR14499:SF9 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010716.1|UniProtKB=W5MXN0 W5MXN0 FAM133B PTHR31911:SF1 PROTEIN FAM133 FAMILY WITH SEQUENCE SIMILARITY 133 MEMBER B-RELATED RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009983.1|UniProtKB=W5MV01 W5MV01 PTHR24388:SF109 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 221-RELATED binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000014924.1|UniProtKB=W5NCL5 W5NCL5 PTHR24241:SF201 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009332.1|UniProtKB=W5MSM8 W5MSM8 PTHR14628:SF1 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN 5 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 LEPOC|Ensembl=ENSLOCG00000004760.1|UniProtKB=W5MBF9 W5MBF9 PTHR46848:SF1 REGULATOR OF G-PROTEIN SIGNALING 3 REGULATOR OF G PROTEIN SIGNALING 3 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000014937.1|UniProtKB=W5NCN3 W5NCN3 PTHR24072:SF137 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 2 anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;establishment or maintenance of cell polarity#GO:0007163;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;actin filament organization#GO:0007015;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014913.1|UniProtKB=W5NCK5 W5NCK5 PTHR13809:SF19 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-8 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane protein complex#GO:0098796;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897 heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Enkephalin release#P05913>G-Protein (s)#P05977;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (i)#P05974;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436 LEPOC|Ensembl=ENSLOCG00000009797.1|UniProtKB=W5MUB4 W5MUB4 PTHR12021:SF5 THYMOSIN BETA THYMOSIN BETA protein binding#GO:0005515;molecular sequestering activity#GO:0140313;binding#GO:0005488;protein sequestering activity#GO:0140311;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin monomer binding#GO:0003785 biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000017054.1|UniProtKB=W5NKB6 W5NKB6 PTHR34399:SF3 AVIDIN-RELATED AVIDIN-RELATED organic acid binding#GO:0043177;ion binding#GO:0043167;binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363 LEPOC|Ensembl=ENSLOCG00000017317.1|UniProtKB=W5NLB3 W5NLB3 PTHR13147:SF5 FOUR-JOINTED BOX PROTEIN 1 FOUR-JOINTED BOX PROTEIN 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 LEPOC|Ensembl=ENSLOCG00000017499.1|UniProtKB=W5NLU5 W5NLU5 PTHR45773:SF4 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 2 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of cellular component biogenesis#GO:0044089;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;regulation of synapse organization#GO:0050807;cell differentiation#GO:0030154;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;cellular developmental process#GO:0048869;positive regulation of synapse assembly#GO:0051965;neurogenesis#GO:0022008;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;neuron projection morphogenesis#GO:0048812;regulation of synapse assembly#GO:0051963;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of cell junction assembly#GO:1901888;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202;glutamatergic synapse#GO:0098978 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017618.1|UniProtKB=W5NM64 W5NM64 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H6 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011664.1|UniProtKB=W5N121 W5N121 PTHR13456:SF0 UPF0729 PROTEIN C18ORF32 UPF0729 PROTEIN C18ORF32 LEPOC|Ensembl=ENSLOCG00000010273.1|UniProtKB=W5MW32 W5MW32 PTHR13723:SF33 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 9 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000015025.1|UniProtKB=W5NCY6 W5NCY6 PTHR12159:SF9 G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA N-glycosylase activity#GO:0019104 base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA glycosylase#PC00010;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011025.1|UniProtKB=W5MYS5 W5MYS5 PTHR13780:SF31 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-3 nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;cation binding#GO:0043169;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488 regulation of carbohydrate metabolic process#GO:0006109;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;response to nutrient levels#GO:0031667;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular response to glucose starvation#GO:0042149;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of carbohydrate biosynthetic process#GO:0043255 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000012258.1|UniProtKB=W5N372 W5N372 PTHR12427:SF1 ATP SYNTHASE E CHAIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT E, MITOCHONDRIAL channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;oxidative phosphorylation#GO:0006119;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753 membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;respiratory chain complex#GO:0098803;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351 ATP synthase#PC00002;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000005397.1|UniProtKB=W5MDP7 W5MDP7 PTHR45665:SF6 AQUAPORIN-8 AQP8A PROTEIN water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 transport#GO:0006810;fluid transport#GO:0042044;water transport#GO:0006833;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000017756.1|UniProtKB=W5NMK1 W5NMK1 PTHR24229:SF111 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;binding#GO:0005488 cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;regulation of insulin secretion#GO:0050796;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular response to steroid hormone stimulus#GO:0071383;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of protein transport#GO:0051223;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of hormone secretion#GO:0046883;biological regulation#GO:0065007;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;response to steroid hormone#GO:0048545;regulation of establishment of protein localization#GO:0070201;cell communication#GO:0007154;regulation of secretion#GO:0051046 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010851.1|UniProtKB=W5MY42 W5MY42 PTHR11711:SF146 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5B GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein localization to Golgi apparatus#GO:0034067;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000013671.1|UniProtKB=W5N893 W5N893 PTHR12190:SF8 A-KINASE ANCHOR PROTEIN AKAP 8 A KINASE (PRKA) ANCHOR PROTEIN 8-LIKE chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014224.1|UniProtKB=W5NA65 W5NA65 PTHR24543:SF317 MULTICOPPER OXIDASE-RELATED LACTADHERIN lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phospholipid binding#GO:0005543 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006786.1|UniProtKB=W5MIJ1 W5MIJ1 PTHR12681:SF0 ZINC FINGER-CONTAINING PROTEIN P48ZNF ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001317.1|UniProtKB=W5LZH0 W5LZH0 PTHR46833:SF1 TELOMERIC REPEAT-BINDING FACTOR 2 TERF2 TELOMERIC REPEAT-BINDING FACTOR 2 nucleic acid binding#GO:0003676;RNA-directed DNA polymerase activity#GO:0003964;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;binding#GO:0005488;single-stranded DNA binding#GO:0003697;transferase activity#GO:0016740;catalytic activity, acting on DNA#GO:0140097;telomerase activity#GO:0003720;DNA polymerase activity#GO:0034061;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162 cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;telomere capping#GO:0016233;organelle organization#GO:0006996;response to stress#GO:0006950;regulation of telomere maintenance via telomere lengthening#GO:1904356;cellular process#GO:0009987;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;regulation of telomere maintenance#GO:0032204;telomere maintenance#GO:0000723;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;localization#GO:0051179;telomere organization#GO:0032200;negative regulation of chromosome organization#GO:2001251;regulation of macromolecule metabolic process#GO:0060255;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;negative regulation of DNA recombination#GO:0045910;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;cellular response to stimulus#GO:0051716 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;nuclear telomere cap complex#GO:0000783;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000015305.1|UniProtKB=W5NDX5 W5NDX5 PTHR21244:SF1 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN US3M translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000001008.1|UniProtKB=W5LYC3 W5LYC3 PTHR28682:SF6 INHIBITORY SYNAPTIC FACTOR 2A-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4-LIKE LEPOC|Ensembl=ENSLOCG00000008819.1|UniProtKB=W5MQR8 W5MQR8 PTHR14224:SF9 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14 LEPOC|Ensembl=ENSLOCG00000001153.1|UniProtKB=W5LYU3 W5LYU3 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;immune response#GO:0006955;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;immune system process#GO:0002376;cell communication#GO:0007154 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004140.1|UniProtKB=W5M9A5 W5M9A5 PTHR12447:SF4 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016068.1|UniProtKB=W5NGP4 W5NGP4 PTHR13667:SF5 HOMOLOC-13 WD REPEAT-CONTAINING AND PLANAR CELL POLARITY EFFECTOR PROTEIN FRITZ HOMOLOG LEPOC|Ensembl=ENSLOCG00000016492.1|UniProtKB=W5NIB2 W5NIB2 PTHR31634:SF2 BLOC-1-RELATED COMPLEX SUBUNIT 5 BLOC-1-RELATED COMPLEX SUBUNIT 5 transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;regulation of transport#GO:0051049;regulation of localization#GO:0032879;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;lysosome localization#GO:0032418;cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;establishment of localization in cell#GO:0051649;organelle transport along microtubule#GO:0072384;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;regulation of microtubule-based movement#GO:0060632 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;side of membrane#GO:0098552;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic side of membrane#GO:0098562;cell junction#GO:0030054;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;secretory vesicle#GO:0099503;lysosomal membrane#GO:0005765;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133 LEPOC|Ensembl=ENSLOCG00000016298.1|UniProtKB=W5NHK5 W5NHK5 PTHR11361:SF148 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH6 ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;catalytic activity, acting on DNA#GO:0140097 nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;mismatch repair#GO:0006298;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001188.1|UniProtKB=W5LYZ1 W5LYZ1 PTHR11216:SF63 EH DOMAIN RALBP1-ASSOCIATED EPS DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;intracellular transport#GO:0046907;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000482.1|UniProtKB=W5LWM2 W5LWM2 PTHR13848:SF56 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 5 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006557.1|UniProtKB=W5MHR3 W5MHR3 PTHR11732:SF402 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1-A catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015717.1|UniProtKB=W5NFD8 W5NFD8 CCDC3 PTHR31663:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of gene expression#GO:0010629;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biological process#GO:0048519;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000004596.1|UniProtKB=W5MAU5 W5MAU5 PTHR15467:SF6 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 3 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015033.1|UniProtKB=W5NCZ6 W5NCZ6 PTHR46003:SF2 HOST CELL FACTOR HOST CELL FACTOR 2 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000015784.1|UniProtKB=W5NFM2 W5NFM2 PTHR23039:SF3 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000016096.1|UniProtKB=W5NGS3 W5NGS3 PTHR11384:SF24 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 2 carboxylic acid transmembrane transporter activity#GO:0046943;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monocarboxylic acid transmembrane transporter activity#GO:0008028;nucleotide binding#GO:0000166;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367 establishment of localization#GO:0051234;lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;transport#GO:0006810;fatty acid metabolic process#GO:0006631;intracellular transport#GO:0046907;monocarboxylic acid catabolic process#GO:0072329;lipid transport#GO:0006869;carboxylic acid catabolic process#GO:0046395;macromolecule localization#GO:0033036;peroxisomal transport#GO:0043574;monocarboxylic acid transport#GO:0015718;lipid oxidation#GO:0034440;localization#GO:0051179;fatty acid transport#GO:0015908;carboxylic acid transmembrane transport#GO:1905039;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;fatty acid oxidation#GO:0019395;metabolic process#GO:0008152;cellular process#GO:0009987;lipid catabolic process#GO:0016042;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;fatty acid catabolic process#GO:0009062;transmembrane transport#GO:0055085;cellular localization#GO:0051641;peroxisome organization#GO:0007031;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;cellular component organization#GO:0016043;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000001552.1|UniProtKB=W5M0B2 W5M0B2 PTHR22829:SF6 DEP DOMAIN PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 1 PROTEIN enzyme inhibitor activity#GO:0004857;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;kinase inhibitor activity#GO:0019210;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function inhibitor activity#GO:0140678;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;G protein-coupled receptor signaling pathway#GO:0007186;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GEF#P00875 LEPOC|Ensembl=ENSLOCG00000017225.1|UniProtKB=W5NKZ4 W5NKZ4 PTHR22444:SF1 GLUTAMATE-RICH PROTEIN 1 GLUTAMATE-RICH PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000001294.1|UniProtKB=W5LZB0 W5LZB0 PTHR13809:SF11 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-3 GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494 heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;GABA-B receptor II signaling#P05731>Ggamma#P05754;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448 LEPOC|Ensembl=ENSLOCG00000005549.1|UniProtKB=W5ME86 W5ME86 PTHR45713:SF8 FTP DOMAIN-CONTAINING PROTEIN SI:CH211-215K15.4 LEPOC|Ensembl=ENSLOCG00000002464.1|UniProtKB=W5M3E2 W5M3E2 PTHR44314:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cilium movement#GO:0003341;organelle assembly#GO:0070925;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium assembly#GO:0060271;cellular component organization#GO:0016043 organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004451.1|UniProtKB=W5MAB7 W5MAB7 PTHR19229:SF29 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA GLUCOSYLCERAMIDE TRANSPORTER ABCA12 protein binding#GO:0005515;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;signaling receptor binding#GO:0005102;binding#GO:0005488;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000017084.1|UniProtKB=W5NKF3 W5NKF3 PTHR16515:SF21 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 13 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000011206.1|UniProtKB=W5MZG1 W5MZG1 PTHR12080:SF59 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE HEPATIC AND GLIAL CELL ADHESION MOLECULE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 intracellular protein localization#GO:0008104;localization#GO:0051179;cell communication#GO:0007154;immune system process#GO:0002376;protein localization to cell junction#GO:1902414;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;immune response#GO:0006955;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule localization#GO:0033036 anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015458.1|UniProtKB=W5NEG5 W5NEG5 PTHR24241:SF164 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PYROGLUTAMYLATED RF-AMIDE PEPTIDE RECEPTOR ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001119.1|UniProtKB=W5LYU4 W5LYU4 PTHR10048:SF107 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;organophosphate metabolic process#GO:0019637;intracellular signaling cassette#GO:0141124;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol phosphate biosynthetic process#GO:0046854;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;cell motility#GO:0048870;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886 kinase#PC00137 Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;p53 pathway feedback loops 2#P04398>P110alpha#P04657;p53 pathway feedback loops 2#P04398>P110ALPHA#G04707;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>P110alpha#P04633;PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;Ras Pathway#P04393>PI3K#P04567;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823;Interleukin signaling pathway#P00036>PI3K#P00990;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>p110alpha#G04694;PI3 kinase pathway#P00048>P110ACT#P01177;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>p110alpha#G04676;VEGF signaling pathway#P00056>PI3K#P01413;PI3 kinase pathway#P00048>p110#P01192;FGF signaling pathway#P00021>PI3K#P00640;B cell activation#P00010>PI3K#P00391;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;T cell activation#P00053>PI3K#P01322;EGF receptor signaling pathway#P00018>PI3K#P00557;Angiogenesis#P00005>PI3K#P00236;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>P110alpha#P04498 LEPOC|Ensembl=ENSLOCG00000003593.1|UniProtKB=W5M7C2 W5M7C2 PTHR43900:SF103 GLUTATHIONE S-TRANSFERASE RHO GLUTATHIONE S-TRANSFERASE RHO small molecule binding#GO:0036094;binding#GO:0005488;glutathione transferase activity#GO:0004364;anion binding#GO:0043168;ion binding#GO:0043167;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000005101.1|UniProtKB=W5MCN2 W5MCN2 PTHR21021:SF16 GAF/PUTATIVE CYTOSKELETAL PROTEIN TIP41-LIKE PROTEIN enzyme activator activity#GO:0008047;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;phosphatase activator activity#GO:0019211;phosphatase regulator activity#GO:0019208;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;molecular function activator activity#GO:0140677;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;TOR signaling#GO:0031929;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000005336.1|UniProtKB=W5MDI2 W5MDI2 PTHR24393:SF5 ZINC FINGER PROTEIN PR_SET DOMAIN 16 transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015148.1|UniProtKB=W5NDD1 W5NDD1 PTHR12329:SF10 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 4 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 regulation of biological quality#GO:0065008;protein stabilization#GO:0050821;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 Apoptosis signaling pathway#P00006>SODD#P00320 LEPOC|Ensembl=ENSLOCG00000007380.1|UniProtKB=W5MKP0 W5MKP0 PTHR16019:SF6 SYNAPSE-ASSOCIATED PROTEIN SYNAPSE-ASSOCIATED PROTEIN 1 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of developmental process#GO:0050793;TORC2 signaling#GO:0038203;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of fat cell differentiation#GO:0045600;biological regulation#GO:0065007;TOR signaling#GO:0031929;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595 endomembrane system#GO:0012505;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010721.1|UniProtKB=W5MXM6 W5MXM6 PTHR21324:SF7 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED TRANSMEMBRANE PROTEIN 150C cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013245.1|UniProtKB=W5N6R6 W5N6R6 PTHR45620:SF2 PDF RECEPTOR-LIKE PROTEIN-RELATED CORTICOTROPIN-RELEASING HORMONE RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;binding#GO:0005488;molecular transducer activity#GO:0060089;hormone binding#GO:0042562;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 transmembrane signal receptor#PC00197 Cortocotropin releasing factor receptor signaling pathway#P04380>CRHR1#P04451 LEPOC|Ensembl=ENSLOCG00000012560.1|UniProtKB=W5N4A7 W5N4A7 PTHR11955:SF89 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, INTESTINAL lipid binding#GO:0008289;fatty acid binding#GO:0005504;organic acid binding#GO:0043177;binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 macromolecule localization#GO:0033036;lipid transport#GO:0006869;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000003394.1|UniProtKB=W5M6L0 W5M6L0 PTHR33504:SF1 NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4 SIMILAR TO HUMAN CHROMOSOME X OPEN READING FRAME 58 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010830.1|UniProtKB=W5MY15 W5MY15 PTHR11153:SF8 SIDEROFLEXIN SIDEROFLEXIN-1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;cellular localization#GO:0051641;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;establishment of localization#GO:0051234;intracellular transport#GO:0046907;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000005983.1|UniProtKB=W5MFS4 W5MFS4 PTHR11732:SF488 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1-B catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013252.1|UniProtKB=W5N6S4 W5N6S4 PTHR12000:SF23 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;catabolic process#GO:0009056;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;lysosome#GO:0005764 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002523.1|UniProtKB=W5M3K1 W5M3K1 PTHR12372:SF4 PECANEX PECANEX-LIKE PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000008003.1|UniProtKB=W5MMW3 W5MMW3 PTHR24366:SF70 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS RETICULON 4 RECEPTOR immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000006754.1|UniProtKB=W5MIE9 W5MIE9 PTHR12812:SF1 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016644.1|UniProtKB=W5NIZ3 W5NIZ3 PTHR46116:SF39 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME DUAL E2 UBIQUITIN-CONJUGATING ENZYME_E3 UBIQUITIN-PROTEIN LIGASE BIRC6 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007419.1|UniProtKB=W5MKU4 W5MKU4 PTHR12080:SF93 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of synapse assembly#GO:0051963;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;filopodium assembly#GO:0046847;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of synapse assembly#GO:0051965;plasma membrane bounded cell projection assembly#GO:0120031;positive regulation of developmental process#GO:0051094;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;cellular response to stimulus#GO:0051716;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;cell communication#GO:0007154;regulation of cell junction assembly#GO:1901888;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of nervous system development#GO:0051962;cell projection organization#GO:0030030;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;immune system process#GO:0002376;regulation of synapse organization#GO:0050807;positive regulation of cellular component organization#GO:0051130 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012386.1|UniProtKB=W5N3Q0 W5N3Q0 PTHR12939:SF6 SARCOGLYCAN DELTA-SARCOGLYCAN heart contraction#GO:0060047;system process#GO:0003008;cardiac muscle tissue development#GO:0048738;animal organ development#GO:0048513;multicellular organism development#GO:0007275;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;heart development#GO:0007507;blood circulation#GO:0008015;muscle tissue development#GO:0060537;system development#GO:0048731;anatomical structure development#GO:0048856;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;heart process#GO:0003015 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;sarcolemma#GO:0042383 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000001089.1|UniProtKB=W5LYM2 W5LYM2 PTHR10258:SF5 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-2 potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 nervous system process#GO:0050877;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;response to calcium ion#GO:0051592;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;detection of chemical stimulus#GO:0009593;action potential#GO:0001508;metal ion transport#GO:0030001;response to stimulus#GO:0050896;transport#GO:0006810;response to metal ion#GO:0010038;transmission of nerve impulse#GO:0019226;system process#GO:0003008;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;detection of stimulus#GO:0051606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;potassium ion transport#GO:0006813;response to chemical#GO:0042221 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000015811.1|UniProtKB=W5NFQ7 W5NFQ7 PTHR45885:SF6 CELL DIVISION CYCLE 5-LIKE PROTEIN CELL DIVISION CYCLE 5-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;regulation of transcription by RNA polymerase II#GO:0006357;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of DNA-templated transcription#GO:0006355;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000009837.1|UniProtKB=W5MUG3 W5MUG3 PTHR12112:SF49 BNIP - RELATED DHHA2 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008460.1|UniProtKB=W5MPI9 W5MPI9 PTHR14074:SF14 HELICASE WITH DEATH DOMAIN-RELATED INTERFERON-INDUCED HELICASE C DOMAIN-CONTAINING PROTEIN 1 double-stranded RNA binding#GO:0003725;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;cation binding#GO:0043169;RNA binding#GO:0003723;metal ion binding#GO:0046872;zinc ion binding#GO:0008270;single-stranded RNA binding#GO:0003727 defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;defense response to virus#GO:0051607;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;immune system process#GO:0002376;biological regulation#GO:0065007;response to other organism#GO:0051707;positive regulation of response to stimulus#GO:0048584;immune response#GO:0006955;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;intracellular receptor signaling pathway#GO:0030522;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;antiviral innate immune response#GO:0140374;innate immune response-activating signaling pathway#GO:0002758;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to virus#GO:0009615;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012365.1|UniProtKB=W5N3L5 W5N3L5 PTHR16022:SF0 WD REPEAT DOMAIN 60 CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;spindle pole#GO:0000922;membraneless organelle#GO:0043228;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;ciliary base#GO:0097546 LEPOC|Ensembl=ENSLOCG00000006852.1|UniProtKB=W5MIS9 W5MIS9 PTHR13439:SF20 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 3A lipid homeostasis#GO:0055088;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004029.1|UniProtKB=W5M8V7 W5M8V7 PTHR11715:SF3 GLYCINE CLEAVAGE SYSTEM H PROTEIN GLYCINE CLEAVAGE SYSTEM H PROTEIN-RELATED metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000017965.1|UniProtKB=W5NN59 W5NN59 PTHR24241:SF83 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 150-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006609.1|UniProtKB=W5MHX7 W5MHX7 PTHR11904:SF13 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;primary metabolic process#GO:0044238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000018336.1|UniProtKB=W5NP78 W5NP78 PTHR24247:SF193 5-HYDROXYTRYPTAMINE RECEPTOR BETA-2 ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;heterocyclic compound binding#GO:1901363;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;serotonin binding#GO:0051378;cation binding#GO:0043169;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001108.1|UniProtKB=W5LYN7 W5LYN7 PTHR46786:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 3 ZINC FINGER MATRIN-TYPE PROTEIN 3 RNA metabolism protein#PC00031;RNA processing factor#PC00147 p53 pathway#P00059>PAG608#G04690 LEPOC|Ensembl=ENSLOCG00000003872.1|UniProtKB=W5M8B7 W5M8B7 PTHR18945:SF196 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-3 signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;molecular transducer activity#GO:0060089;monoatomic anion channel activity#GO:0005253;ligand-gated monoatomic ion channel activity#GO:0015276 transport#GO:0006810;chloride transport#GO:0006821;establishment of localization#GO:0051234;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic anion transmembrane transport#GO:0098656;trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916 cell junction#GO:0030054;signaling receptor complex#GO:0043235;synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000013642.1|UniProtKB=W5N868 W5N868 PTHR16200:SF4 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE ARKADIA aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001760.1|UniProtKB=W5M0Y0 W5M0Y0 PTHR22883:SF417 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC20 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096 protein targeting to membrane#GO:0006612;developmental process#GO:0032502;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;vesicle organization#GO:0016050;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;developmental maturation#GO:0021700;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;protein targeting#GO:0006605 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003189.1|UniProtKB=W5M5Y0 W5M5Y0 PTHR13601:SF4 GAMETOGENETIN-BINDING PROTEIN 2 GAMETOGENETIN-BINDING PROTEIN 2 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of cell communication#GO:0010646 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007031.1|UniProtKB=W5MJF6 W5MJF6 PTHR19353:SF12 FATTY ACID DESATURASE 2 ACYL-COA 6-DESATURASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016036.1|UniProtKB=W5NGJ2 W5NGJ2 PTHR10188:SF16 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE- LIKE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009825.1|UniProtKB=W5MUF2 W5MUF2 PTHR10372:SF3 PLAKOPHILLIN-RELATED PLAKOPHILIN-1 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;nucleus#GO:0005634;cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 intermediate filament binding protein#PC00130;cytoskeletal protein#PC00085;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000017952.1|UniProtKB=W5NN46 W5NN46 PTHR48043:SF52 EG:EG0003.4 PROTEIN-RELATED UDP GLUCURONOSYLTRANSFERASE 5 FAMILY, POLYPEPTIDE B2-RELATED UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 LEPOC|Ensembl=ENSLOCG00000000323.1|UniProtKB=W5LW42 W5LW42 PTHR24394:SF33 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 8B DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011411.1|UniProtKB=W5N066 W5N066 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007059.1|UniProtKB=W5MJI7 W5MJI7 PTHR21538:SF27 ANILLIN/RHOTEKIN RTKN ANILLIN actomyosin contractile ring assembly#GO:0000915;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;septin cytoskeleton organization#GO:0032185;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;cell division#GO:0051301;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;mitotic cell cycle#GO:0000278;actomyosin structure organization#GO:0031032;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;actin filament-based process#GO:0030029;cytokinetic process#GO:0032506;cortical actin cytoskeleton organization#GO:0030866;septin ring organization#GO:0031106;cytoskeleton-dependent cytokinesis#GO:0061640 intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;contractile ring#GO:0070938;actomyosin contractile ring#GO:0005826;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;cell periphery#GO:0071944 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000010849.1|UniProtKB=W5MY40 W5MY40 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010506.1|UniProtKB=W5MWW6 W5MWW6 PTHR15692:SF8 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 3 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000008977.1|UniProtKB=W5MRD2 W5MRD2 PTHR13962:SF20 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000001833.1|UniProtKB=W5M184 W5M184 PTHR11945:SF25 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2C sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;sequence-specific double-stranded DNA binding#GO:1990837;histone deacetylase binding#GO:0042826;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;heart development#GO:0007507;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 MADS box transcription factor#PC00250 Oxidative stress response#P00046>MEF-2#P01128;p38 MAPK pathway#P05918>MEF#P06023;CCKR signaling map#P06959>MEF2C#P07222 LEPOC|Ensembl=ENSLOCG00000016362.1|UniProtKB=W5NHU9 W5NHU9 PTHR44395:SF1 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC3 LEPOC|Ensembl=ENSLOCG00000016958.1|UniProtKB=W5NK07 W5NK07 PTHR11783:SF107 SULFOTRANSFERASE SULT SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007833.1|UniProtKB=W5MMA0 W5MMA0 PTHR15821:SF0 PROTEIN MN1 TRANSCRIPTIONAL ACTIVATOR MN1 LEPOC|Ensembl=ENSLOCG00000014444.1|UniProtKB=W5NAW9 W5NAW9 PTHR18895:SF74 HEMK METHYLTRANSFERASE MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276 biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;protein-containing complex disassembly#GO:0032984;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;translation#GO:0006412;translational termination#GO:0006415 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008633.1|UniProtKB=W5MQ34 W5MQ34 PTHR15201:SF1 CRSP70 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000010437.1|UniProtKB=W5MWN1 W5MWN1 PTHR11334:SF57 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G PROTEIN-COUPLED RECEPTOR MEMBER D plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003137.1|UniProtKB=W5M5N4 W5M5N4 PTHR11640:SF164 NEPHRIN OPIOID BINDING PROTEIN_CELL ADHESION MOLECULE LIKE protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000007414.1|UniProtKB=W5MKT3 W5MKT3 PTHR23235:SF3 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP3 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 CCKR signaling map#P06959>SP3#P07041 LEPOC|Ensembl=ENSLOCG00000016210.1|UniProtKB=W5NH73 W5NH73 PTHR28592:SF2 ARMADILLO REPEAT-CONTAINING PROTEIN 1 ARMADILLO REPEAT-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009465.1|UniProtKB=W5MT47 W5MT47 PTHR21041:SF2 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN leukocyte differentiation#GO:0002521;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;cell development#GO:0048468;reproductive process#GO:0022414;fertilization#GO:0009566;cell-cell fusion#GO:0140253;sexual reproduction#GO:0019953;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;osteoclast differentiation#GO:0030316;single fertilization#GO:0007338;cellular process#GO:0009987;hemopoiesis#GO:0030097;developmental process#GO:0032502;cellular developmental process#GO:0048869 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cell surface#GO:0009986;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000016982.1|UniProtKB=W5NK33 W5NK33 PTHR24241:SF17 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V1A RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of biological quality#GO:0065008;cell communication#GO:0007154;circulatory system process#GO:0003013;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to hormone#GO:0009725;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007786.1|UniProtKB=W5MM44 W5MM44 PTHR12027:SF91 WNT RELATED PROTO-ONCOGENE WNT-1 signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 signaling#GO:0023052;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell fate commitment#GO:0045165;system development#GO:0048731;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 LEPOC|Ensembl=ENSLOCG00000002946.1|UniProtKB=W5M505 W5M505 PTHR24061:SF418 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007529.1|UniProtKB=W5ML78 W5ML78 PTHR22793:SF5 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN-RELATED TRANSCRIPTION FACTOR B muscle cell differentiation#GO:0042692;cellular process#GO:0009987;cell differentiation#GO:0030154;muscle structure development#GO:0061061;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000005904.1|UniProtKB=W5MFG7 W5MFG7 PTHR47978:SF4 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33B-LIKE hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553 regulation of secretion#GO:0051046;vacuole organization#GO:0007033;regulation of exocytosis#GO:0017157;process utilizing autophagic mechanism#GO:0061919;regulation of secretion by cell#GO:1903530;organelle assembly#GO:0070925;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;regulation of localization#GO:0032879;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;cellular component assembly#GO:0022607;biological regulation#GO:0065007;macroautophagy#GO:0016236;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000009771.1|UniProtKB=W5MU76 W5MU76 PTHR35449:SF1 PROTEIN SIX6OS1 PROTEIN SIX6OS1 macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;cellular developmental process#GO:0048869;meiotic nuclear division#GO:0140013;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;DNA repair#GO:0006281;developmental process#GO:0032502;spermatogenesis#GO:0007283;DNA damage response#GO:0006974;male gamete generation#GO:0048232;nucleobase-containing compound metabolic process#GO:0006139;anatomical structure development#GO:0048856;organelle fission#GO:0048285;multicellular organismal reproductive process#GO:0048609;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;germ cell development#GO:0007281;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;homologous chromosome pairing at meiosis#GO:0007129;oogenesis#GO:0048477;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;response to stimulus#GO:0050896;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle process#GO:0022402 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;central element#GO:0000801;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;synaptonemal structure#GO:0099086;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793 LEPOC|Ensembl=ENSLOCG00000001581.1|UniProtKB=W5M0A5 W5M0A5 PTHR11905:SF258 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 12 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013174.1|UniProtKB=W5N6H5 W5N6H5 PTHR14130:SF13 3BP-1 RELATED RHOGAP RHO GTPASE-ACTIVATING PROTEIN 44 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of actin cytoskeleton organization#GO:0032956;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of neuron projection development#GO:0010975;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of response to stimulus#GO:0048583;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;regulation of synapse structure or activity#GO:0050803;negative regulation of intracellular signal transduction#GO:1902532;regulation of synapse organization#GO:0050807;regulation of signaling#GO:0023051;regulation of dendritic spine morphogenesis#GO:0061001;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 cell junction#GO:0030054;presynaptic active zone#GO:0048786;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;presynapse#GO:0098793;cell periphery#GO:0071944;dendrite#GO:0030425;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794;dendritic spine#GO:0043197 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000016662.1|UniProtKB=W5NIX3 W5NIX3 PTHR10137:SF4 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C 2 monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078 transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000007404.1|UniProtKB=W5MKS8 W5MKS8 EIF3G PTHR10352:SF88 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000003456.1|UniProtKB=W5M6T6 W5M6T6 PTHR48024:SF28 GEO13361P1-RELATED RNA-BINDING PROTEIN 38 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000002679.1|UniProtKB=W5M455 W5M455 PTHR10846:SF28 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 3 ISOFORM X1 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;antiporter activity#GO:0015297;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000017432.1|UniProtKB=W5NLM8 W5NLM8 PTHR12002:SF225 CLAUDIN CLAUDIN cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular process#GO:0009987;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;transport#GO:0006810;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;paracellular transport#GO:0160184 tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000013053.1|UniProtKB=W5N623 W5N623 PTHR11771:SF96 LIPOXYGENASE ZGC:152891 catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;icosanoid metabolic process#GO:0006690;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;lipid oxidation#GO:0034440;arachidonate metabolic process#GO:0019369;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000009297.1|UniProtKB=W5MSI2 W5MSI2 PTHR21669:SF2 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS CAPZ-INTERACTING PROTEIN lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543 transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;protein localization to organelle#GO:0033365 intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018038.1|UniProtKB=W5NND0 W5NND0 PTHR24248:SF25 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2C ADRENERGIC RECEPTOR binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;cation binding#GO:0043169;hormone binding#GO:0042562;G protein-coupled amine receptor activity#GO:0008227;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 LEPOC|Ensembl=ENSLOCG00000000824.1|UniProtKB=W5LXR0 W5LXR0 PTHR10032:SF220 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS TRANSCRIPTION FACTOR OVO-LIKE PROTEIN 3-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;epidermis development#GO:0008544;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000011569.1|UniProtKB=W5N0Q7 W5N0Q7 PTHR46091:SF1 BLR7054 PROTEIN ALL-TRANS-RETINOL 13,14-REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 cellular process#GO:0009987;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281;olefinic compound metabolic process#GO:0120254;retinol metabolic process#GO:0042572;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010284.1|UniProtKB=W5MW39 W5MW39 PTHR18884:SF50 SEPTIN SEPTIN-10 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 macromolecule localization#GO:0033036;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;intracellular protein localization#GO:0008104;cytokinesis#GO:0000910 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;cell cortex#GO:0005938;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000007693.1|UniProtKB=W5MLT6 W5MLT6 PTHR11889:SF84 HEDGEHOG HEDGEHOG PROTEIN signaling receptor binding#GO:0005102;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169 cell surface receptor signaling pathway#GO:0007166;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;cell fate commitment#GO:0045165;smoothened signaling pathway#GO:0007224;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000012621.1|UniProtKB=W5N4I3 W5N4I3 PTHR10663:SF329 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 2 ruffle#GO:0001726;cell projection membrane#GO:0031253;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000013585.1|UniProtKB=W5N7Z6 W5N7Z6 PTHR13610:SF8 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN ATP SYNTHASE SUBUNIT C LYSINE N-METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of system process#GO:0044057 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013108.1|UniProtKB=W5N690 W5N690 PTHR11562:SF27 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A4-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;response to stimulus#GO:0050896;metal ion transport#GO:0030001;establishment of localization#GO:0051234;transport#GO:0006810;response to metal ion#GO:0010038;response to chemical#GO:0042221;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002758.1|UniProtKB=W5M4E3 W5M4E3 PTHR28623:SF1 PROTEIN FAM118B PROTEIN FAM118B hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824 defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 LEPOC|Ensembl=ENSLOCG00000012617.1|UniProtKB=W5N4H7 W5N4H7 PTHR23036:SF163 CYTOKINE RECEPTOR CYTOKINE RECEPTOR-LIKE FACTOR 2 signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016105.1|UniProtKB=W5NGT3 W5NGT3 PTHR11871:SF2 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B ALPHA ISOFORM phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629 LEPOC|Ensembl=ENSLOCG00000007356.1|UniProtKB=W5MKK2 W5MKK2 PTHR33776:SF3 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000001218.1|UniProtKB=W5LZ25 W5LZ25 PTHR42758:SF1 PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C LYSOPHOSPHOLIPASE D GDPD1 catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid catabolic process#GO:0016042;organophosphate metabolic process#GO:0019637;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;glycerophospholipid catabolic process#GO:0046475;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002748.1|UniProtKB=W5M4F2 W5M4F2 PTHR11132:SF238 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER H1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;nitrogen compound transport#GO:0071705;nucleotide-sugar transmembrane transport#GO:0015780;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010778.1|UniProtKB=W5MXU5 W5MXU5 PTHR10454:SF240 CASPASE CASPASE-10 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;biological regulation#GO:0065007;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;regulation of neuron apoptotic process#GO:0043523;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of apoptotic process#GO:0043065;positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981 intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 protein modifying enzyme#PC00260;protease#PC00190 Huntington disease#P00029>Caspase 8#P00808;FAS signaling pathway#P00020>Pro-Caspase10#P00598;Apoptosis signaling pathway#P00006>Caspase 10#P00295;Huntington disease#P00029>Pro-caspase 8#P00767;FAS signaling pathway#P00020>Caspase8#P00594;FAS signaling pathway#P00020>Pro-Caspase8#P00604;FAS signaling pathway#P00020>Caspase10#P00606;Apoptosis signaling pathway#P00006>Caspase 8#P00299 LEPOC|Ensembl=ENSLOCG00000004555.1|UniProtKB=W5MAN8 W5MAN8 PTHR24064:SF673 SOLUTE CARRIER FAMILY 22 MEMBER SYNAPTIC VESICLE 2-RELATED PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000015860.1|UniProtKB=W5NFW8 W5NFW8 PTHR23043:SF37 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN PROTEIN 4 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000013851.1|UniProtKB=W5N8X3 W5N8X3 PTHR22802:SF475 C-TYPE LECTIN SUPERFAMILY MEMBER CD302 ANTIGEN binding#GO:0005488;signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015041.1|UniProtKB=W5ND03 W5ND03 PTHR12137:SF32 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 11 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000010153.1|UniProtKB=W5MVM2 W5MVM2 PTHR17611:SF3 DNA SEGMENT, CHR 5, ERATO DOI 579, EXPRESSED KIAA0232 HOMOLOG LEPOC|Ensembl=ENSLOCG00000011384.1|UniProtKB=W5N035 W5N035 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005907.1|UniProtKB=W5MFH8 W5MFH8 PTHR46299:SF2 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2-RELATED VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2 LEPOC|Ensembl=ENSLOCG00000008172.1|UniProtKB=W5MNG3 W5MNG3 PTHR12622:SF7 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX1 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;developmental process#GO:0032502;cellular developmental process#GO:0048869;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;neurogenesis#GO:0022008;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;gliogenesis#GO:0042063;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;proteasomal protein catabolic process#GO:0010498;animal gross anatomical part developmental process#GO:0160108;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016973.1|UniProtKB=W5NK23 W5NK23 PTHR24418:SF468 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FRK catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;non-membrane spanning protein tyrosine kinase activity#GO:0004715;signaling receptor binding#GO:0005102;binding#GO:0005488 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Blk#P00390;Integrin signalling pathway#P00034>Src#P00940;Parkinson disease#P00049>Src kinase#P01230;Parkinson disease#P00049>Fyn kinase#P01235;Axon guidance mediated by semaphorins#P00007>Fyn#P00335;Cadherin signaling pathway#P00012>Fyn#P00464 LEPOC|Ensembl=ENSLOCG00000017319.1|UniProtKB=W5NLB5 W5NLB5 PTHR15478:SF8 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 2 LEPOC|Ensembl=ENSLOCG00000003735.1|UniProtKB=W5M7T1 W5M7T1 PTHR11599:SF40 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-7 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome complex#GO:0000502;nucleus#GO:0005634;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000000162.1|UniProtKB=W5LVM0 W5LVM0 PTHR48071:SF37 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009112.1|UniProtKB=W5MRV4 W5MRV4 PTHR45961:SF1 IP21249P DUAL SPECIFICITY PROTEIN PHOSPHATASE 18 ISOFORM X1 hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 LEPOC|Ensembl=ENSLOCG00000011741.1|UniProtKB=W5N1C9 W5N1C9 PTHR13664:SF0 BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR enzyme regulator activity#GO:0030234;protein-membrane adaptor activity#GO:0043495;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;cellular response to nutrient levels#GO:0031669;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;cellular response to starvation#GO:0009267;metabolic process#GO:0008152;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;localization#GO:0051179;cellular response to stress#GO:0033554;organelle localization#GO:0051640;organelle assembly#GO:0070925;protein-containing complex disassembly#GO:0032984;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594 membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;extrinsic component of membrane#GO:0019898;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;autophagosome#GO:0005776;transferase complex, transferring phosphorus-containing groups#GO:0061695;phosphatidylinositol 3-kinase complex, class III#GO:0035032;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000000941.1|UniProtKB=W5LY75 W5LY75 PTHR16777:SF2 PROTEIN ECT2 PROTEIN ECT2 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;cell periphery#GO:0071944;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007563.1|UniProtKB=W5MLB9 W5MLB9 PTHR14938:SF2 HCLS1-ASSOCIATED PROTEIN X-1 HCLS1-ASSOCIATED PROTEIN X-1 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;response to peptide#GO:1901652;regulation of actin filament length#GO:0030832;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament organization#GO:0110053;regulation of actin filament-based process#GO:0032970;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221 intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;actin cytoskeleton#GO:0015629;mitochondrion#GO:0005739;vesicle#GO:0031982;membraneless organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;apical part of cell#GO:0045177;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;sarcoplasmic reticulum#GO:0016529 LEPOC|Ensembl=ENSLOCG00000000669.1|UniProtKB=W5LXD2 W5LXD2 PTHR24394:SF0 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 40 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008548.1|UniProtKB=W5MPT9 W5MPT9 PTHR23167:SF52 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED SMOOTHELIN actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015551.1|UniProtKB=W5NET7 W5NET7 PTHR10666:SF437 UBIQUITIN POLYUBIQUITIN-B structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000011260.1|UniProtKB=W5MZM7 W5MZM7 PTHR14614:SF167 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTONE-ARGININE METHYLTRANSFERASE METTL23 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010581.1|UniProtKB=W5MX55 W5MX55 PTHR11849:SF10 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000012271.1|UniProtKB=W5N388 W5N388 PTHR21230:SF99 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 2 binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;SNAP receptor activity#GO:0005484 organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;intra-Golgi vesicle-mediated transport#GO:0006891;localization#GO:0051179 COPII-coated ER to Golgi transport vesicle#GO:0030134;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 membrane traffic protein#PC00150;SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000004002.1|UniProtKB=W5M8T6 W5M8T6 PTHR42918:SF16 LYSYL-TRNA SYNTHETASE LYSINE--TRNA LIGASE catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;nucleic acid binding#GO:0003676;adenylyltransferase activity#GO:0070566;RNA binding#GO:0003723;tRNA binding#GO:0000049;catalytic activity, acting on a tRNA#GO:0140101 organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;translation#GO:0006412;cell activation#GO:0001775;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;leukocyte activation#GO:0045321;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of cell activation#GO:0050867;amino acid metabolic process#GO:0006520;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637;tRNA aminoacylation#GO:0043039;nucleotide biosynthetic process#GO:0009165;cell activation involved in immune response#GO:0002263;nucleotide metabolic process#GO:0009117;RNA metabolic process#GO:0016070;immune system process#GO:0002376;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;protein biosynthetic process#GO:0160307;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;positive regulation of leukocyte activation#GO:0002696;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;regulation of multicellular organismal process#GO:0051239;myeloid leukocyte activation#GO:0002274;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;regulation of macrophage activation#GO:0043030;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013877.1|UniProtKB=W5N905 W5N905 PTHR24410:SF21 HL07962P-RELATED BTB DOMAIN-CONTAINING PROTEIN defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002750.1|UniProtKB=W5M4D2 W5M4D2 PTHR47120:SF1 THAP DOMAIN-CONTAINING PROTEIN 3 THAP DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000010934.1|UniProtKB=W5MYG1 W5MYG1 PTHR43866:SF3 MALONATE-SEMIALDEHYDE DEHYDROGENASE METHYLMALONATE-SEMIALDEHYDE_MALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;pyrimidine nucleobase catabolic process#GO:0006208;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;nucleobase catabolic process#GO:0046113;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 Pyrimidine Metabolism#P02771>Methylmalonate Semialdehyde Dehydrogenase#P03124 LEPOC|Ensembl=ENSLOCG00000007449.1|UniProtKB=W5ML05 W5ML05 PTHR10749:SF5 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA, LIVER ISOFORM intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 LEPOC|Ensembl=ENSLOCG00000002046.1|UniProtKB=W5M1W6 W5M1W6 PTHR13832:SF233 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1F catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 regulation of actin filament-based process#GO:0032970;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;cell communication#GO:0007154;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of actin filament bundle assembly#GO:0032231;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000011181.1|UniProtKB=W5MZC7 W5MZC7 PTHR24103:SF595 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 14 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000017106.1|UniProtKB=W5NKH8 W5NKH8 PTHR10283:SF63 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005230.1|UniProtKB=W5MD38 W5MD38 PTHR31978:SF3 INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;protein localization to cilium#GO:0061512;cellular component organization#GO:0016043;cilium assembly#GO:0060271;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006176.1|UniProtKB=W5MGF3 W5MGF3 PTHR23086:SF46 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE-LIKE PROTEIN 1 lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742 organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 kinase#PC00137;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000008153.1|UniProtKB=W5MND7 W5MND7 PTHR24245:SF6 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 26 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013534.1|UniProtKB=W5N7T2 W5N7T2 PTHR47958:SF90 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX5-RELATED catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000000442.1|UniProtKB=W5LWH9 W5LWH9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000018131.1|UniProtKB=W5NNM3 W5NNM3 PTHR10489:SF922 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 2 ISOFORM X1-RELATED cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515 regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012377.1|UniProtKB=W5N3N2 W5N3N2 PTHR10672:SF5 ADDUCIN GAMMA-ADDUCIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of protein depolymerization#GO:1901879;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament organization#GO:0110053;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903 organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000012718.1|UniProtKB=W5N4U3 W5N4U3 PTHR47966:SF66 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSINOGEN C catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;aspartic protease#PC00053 LEPOC|Ensembl=ENSLOCG00000009847.1|UniProtKB=W5MUI1 W5MUI1 PTHR22988:SF84 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE MRCK BETA catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011695.1|UniProtKB=W5N163 W5N163 PTHR13020:SF32 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6B PROTEIN positive regulation of mRNA catabolic process#GO:0061014;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;miRNA-mediated post-transcriptional gene silencing#GO:0035195;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311 cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016918.1|UniProtKB=W5NJW7 W5NJW7 PTHR24023:SF917 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000011347.1|UniProtKB=W5MZY6 W5MZY6 PTHR19969:SF13 SH2-SH3 ADAPTOR PROTEIN-RELATED OSTEOCLAST-STIMULATING FACTOR 1 receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;binding#GO:0005488 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017120.1|UniProtKB=W5NKJ8 W5NKJ8 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000012625.1|UniProtKB=W5N4I5 W5N4I5 PTHR23040:SF1 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4 OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007487.1|UniProtKB=W5ML30 W5ML30 PANX PTHR15759:SF5 PANNEXIN PANNEXIN-1 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008013.1|UniProtKB=W5MMX0 W5MMX0 PTHR15273:SF8 DAN DOMAIN FAMILY MEMBER 5 DAN DOMAIN FAMILY MEMBER 5 PRECURSOR LEPOC|Ensembl=ENSLOCG00000004259.1|UniProtKB=W5M9N5 W5M9N5 PTHR35480:SF1 MATERNAL EFFECT EMBRYO ARREST 22 MATERNAL EFFECT EMBRYO ARREST 22 LEPOC|Ensembl=ENSLOCG00000014793.1|UniProtKB=W5NC56 W5NC56 PTHR24329:SF588 HOMEOBOX PROTEIN ARISTALESS ARISTALESS RELATED HOMEOBOX double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000017335.1|UniProtKB=W5NLD1 W5NLD1 PTHR21461:SF45 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008487.1|UniProtKB=W5MPL6 W5MPL6 PTHR33558:SF1 GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008039.1|UniProtKB=W5MN17 W5MN17 PTHR46556:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 lysosome localization#GO:0032418;cellular process#GO:0009987;regulation of biological process#GO:0050789;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;organelle localization#GO:0051640;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179 endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000005813.1|UniProtKB=W5MF64 W5MF64 PTHR21405:SF0 CDNA SEQUENCE BC021608 TETRATRICOPEPTIDE REPEAT PROTEIN 36 LEPOC|Ensembl=ENSLOCG00000000494.1|UniProtKB=W5LWN1 W5LWN1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006135.1|UniProtKB=W5MGA4 W5MGA4 PTHR23227:SF87 BUCENTAUR RELATED PROTEIN CFDP2 LEPOC|Ensembl=ENSLOCG00000005027.1|UniProtKB=W5MCE5 W5MCE5 PTHR21243:SF21 PROTEIN SCAI PROTEIN SCAI transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015394.1|UniProtKB=W5NE83 W5NE83 PTHR24369:SF163 ANTIGEN BSP, PUTATIVE-RELATED MATRIX-REMODELING-ASSOCIATED PROTEIN 5 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008953.1|UniProtKB=W5MRA4 W5MRA4 PTHR45817:SF5 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 4 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000000264.1|UniProtKB=W5LVY1 W5LVY1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014598.1|UniProtKB=W5NBF6 W5NBF6 PTHR28314:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000003937.1|UniProtKB=W5M8K0 W5M8K0 PTHR45633:SF56 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 regulation of cell activation#GO:0050865;T cell activation#GO:0042110;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;positive regulation of metabolic process#GO:0009893;response to stress#GO:0006950;positive regulation of cell-cell adhesion#GO:0022409;regulation of multicellular organismal process#GO:0051239;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;positive regulation of leukocyte activation#GO:0002696;metabolic process#GO:0008152;positive regulation of cell adhesion#GO:0045785;cell death#GO:0008219;leukocyte activation#GO:0045321;positive regulation of cytokine production#GO:0001819;cell activation#GO:0001775;cellular response to unfolded protein#GO:0034620;protein metabolic process#GO:0019538;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;regulation of macromolecule biosynthetic process#GO:0010556;mitochondrial protein import pathway#GO:7770058;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;establishment of localization#GO:0051234;positive regulation of multicellular organismal process#GO:0051240;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;mitochondrial transport#GO:0006839;immune system process#GO:0002376;cellular localization#GO:0051641;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;organelle organization#GO:0006996;protein maturation#GO:0051604;gene expression#GO:0010467;lymphocyte activation#GO:0046649;positive regulation of macromolecule metabolic process#GO:0010604;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;positive regulation of type I interferon production#GO:0032481;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of macromolecule metabolic process#GO:0060255;cellular response to topologically incorrect protein#GO:0035967;positive regulation of lymphocyte activation#GO:0051251;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of cell activation#GO:0050867;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biosynthetic process#GO:0009058;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;transport#GO:0006810;intracellular transport#GO:0046907;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle lumen#GO:0043233;organelle membrane#GO:0031090;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000018083.1|UniProtKB=W5NNH5 W5NNH5 PTHR33332:SF54 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005741.1|UniProtKB=W5MEX6 W5MEX6 PTHR12156:SF22 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 3 LEPOC|Ensembl=ENSLOCG00000017951.1|UniProtKB=W5NN45 W5NN45 PTHR20937:SF17 IP14615P MESODERM POSTERIOR PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;mesoderm morphogenesis#GO:0048332;heart morphogenesis#GO:0003007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regionalization#GO:0003002;mesoderm formation#GO:0001707;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;formation of primary germ layer#GO:0001704;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;gastrulation#GO:0007369;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;mesoderm development#GO:0007498;anterior/posterior axis specification#GO:0009948;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anatomical structure formation involved in morphogenesis#GO:0048646;anterior/posterior pattern specification#GO:0009952;heart development#GO:0007507;embryo development#GO:0009790;embryonic pattern specification#GO:0009880 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001340.1|UniProtKB=W5LZG2 W5LZG2 PTHR15545:SF6 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 PDZ DOMAIN-CONTAINING RING FINGER PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000005975.1|UniProtKB=W5MFR0 W5MFR0 PTHR26451:SF886 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004627.1|UniProtKB=W5MAY5 W5MAY5 PTHR14948:SF1 NG5 TRAFFICKING REGULATOR OF GLUT4 1 cellular response to hormone stimulus#GO:0032870;endocytic recycling#GO:0032456;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to endogenous stimulus#GO:0009719;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;protein transport#GO:0015031;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;vesicle-mediated transport#GO:0016192;response to chemical#GO:0042221;response to hormone#GO:0009725;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular response to oxygen-containing compound#GO:1901701;establishment of protein localization#GO:0045184;endosomal transport#GO:0016197;protein localization to cell periphery#GO:1990778;intracellular protein transport#GO:0006886;cellular response to peptide hormone stimulus#GO:0071375;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;localization#GO:0051179;response to nitrogen compound#GO:1901698;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;cellular response to nitrogen compound#GO:1901699;response to peptide hormone#GO:0043434;macromolecule localization#GO:0033036;endosome to plasma membrane protein transport#GO:0099638;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;transport#GO:0006810;cellular response to insulin stimulus#GO:0032869 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular vesicle#GO:0097708;vesicle membrane#GO:0012506;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004580.1|UniProtKB=W5MAX0 W5MAX0 PTHR11405:SF58 CARBAMOYLTRANSFERASE FAMILY MEMBER CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925;Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845 LEPOC|Ensembl=ENSLOCG00000006781.1|UniProtKB=W5MII2 W5MII2 PTHR43963:SF4 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE (NADPH) alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005981.1|UniProtKB=W5MFS0 W5MFS0 PTHR11886:SF113 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 2, CYTOPLASMIC microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000014642.1|UniProtKB=W5NBL1 W5NBL1 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005885.1|UniProtKB=W5MFF8 W5MFF8 PTHR12276:SF50 EPSIN/ENT-RELATED EPSIN-2 lipid binding#GO:0008289;protein binding#GO:0005515;clathrin binding#GO:0030276;phospholipid binding#GO:0005543;binding#GO:0005488 import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;vesicle coat#GO:0030120;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle#GO:0030136;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;endosome#GO:0005768 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008694.1|UniProtKB=W5MQC4 W5MQC4 PTHR48092:SF19 KNIRPS-RELATED PROTEIN-RELATED MINERALOCORTICOID RECEPTOR sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;cellular response to steroid hormone stimulus#GO:0071383;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;regulation of nucleobase-containing compound metabolic process#GO:0019219;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;steroid hormone receptor signaling pathway#GO:0043401;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;response to steroid hormone#GO:0048545;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000016560.1|UniProtKB=W5NIJ5 W5NIJ5 PTHR16317:SF1 INTEGRIN ALPHA REPEAT DOMAIN-CONTAINING KICSTOR COMPLEX PROTEIN ITFG2 regulation of TORC1 signaling#GO:1903432;negative regulation of TORC1 signaling#GO:1904262;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to nutrient levels#GO:0031667;response to stress#GO:0006950;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;negative regulation of biological process#GO:0048519 protein-containing complex#GO:0032991 integrin#PC00126 LEPOC|Ensembl=ENSLOCG00000005324.1|UniProtKB=W5MDG2 W5MDG2 PTHR10749:SF8 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 LEPOC|Ensembl=ENSLOCG00000000092.1|UniProtKB=W5LWG7 W5LWG7 PTHR46096:SF1 PERFORIN-1 PERFORIN 1.5-RELATED passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 immune effector process#GO:0002252;cell killing#GO:0001906;cell-cell recognition#GO:0009988;defense response#GO:0006952;response to external stimulus#GO:0009605;cellular process#GO:0009987;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;adaptive immune response#GO:0002250;response to other organism#GO:0051707;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;cell activation#GO:0001775;cell recognition#GO:0008037;T cell mediated immunity#GO:0002456;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;response to virus#GO:0009615;leukocyte mediated cytotoxicity#GO:0001909;defense response to virus#GO:0051607;leukocyte activation#GO:0045321;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000011932.1|UniProtKB=W5N215 W5N215 PTHR15725:SF24 ZN-FINGER, C-X8-C-X5-C-X3-H TYPE-CONTAINING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 11A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000001396.1|UniProtKB=W5LZT2 W5LZT2 PTHR10574:SF445 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA 3 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 tissue development#GO:0009888;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000013618.1|UniProtKB=W5N832 W5N832 PTHR44464:SF1 WD REPEAT-CONTAINING PROTEIN 17 WD REPEAT-CONTAINING PROTEIN 17 LEPOC|Ensembl=ENSLOCG00000012089.1|UniProtKB=W5N2L9 W5N2L9 PTHR14753:SF3 F-BOX ONLY PROTEIN 38 F-BOX ONLY PROTEIN 38 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;positive regulation of adaptive immune response#GO:0002821;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of lymphocyte mediated immunity#GO:0002706;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of leukocyte mediated immunity#GO:0002703;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of response to biotic stimulus#GO:0002831;catabolic process#GO:0009056;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;biological regulation#GO:0065007;positive regulation of immune effector process#GO:0002699;post-translational protein modification#GO:0043687;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;protein K48-linked ubiquitination#GO:0070936;positive regulation of leukocyte mediated immunity#GO:0002705;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;positive regulation of response to biotic stimulus#GO:0002833;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000012859.1|UniProtKB=W5N5C2 W5N5C2 PTHR14440:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 cellular component biogenesis#GO:0044085;transcription by RNA polymerase I#GO:0006360;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase I promoter#GO:0006361;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000001891.1|UniProtKB=W5M1F7 W5M1F7 PTHR19876:SF1 COATOMER COATOMER SUBUNIT ALPHA retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 COPI-coated vesicle#GO:0030137;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000001890.1|UniProtKB=W5M1D5 W5M1D5 PTHR24336:SF12 TRANSCRIPTION FACTOR LBX TRANSCRIPTION FACTOR LBX2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010540.1|UniProtKB=W5MX10 W5MX10 PTHR42902:SF2 MALATE SYNTHASE MALATE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;glyoxylate metabolic process#GO:0046487;carbohydrate metabolic process#GO:0005975;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000008161.1|UniProtKB=W5MNE5 W5MNE5 PTHR37456:SF3 SI:CH211-266K2.1 COLLAGEN ALPHA-1(XXV) CHAIN binding#GO:0005488;peptide binding#GO:0042277 LEPOC|Ensembl=ENSLOCG00000001729.1|UniProtKB=W5M0U1 W5M0U1 PTHR14198:SF15 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 4 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000001683.1|UniProtKB=W5M0N0 W5M0N0 PTHR45699:SF3 60S ACIDIC RIBOSOMAL PROTEIN P0 LARGE RIBOSOMAL SUBUNIT PROTEIN UL10 structural constituent of ribosome#GO:0003735;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015998.1|UniProtKB=W5NGE3 W5NGE3 PTHR42884:SF13 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 2 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;proteolysis#GO:0006508;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;biological regulation#GO:0065007;peptide hormone processing#GO:0016486;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 neuron projection#GO:0043005;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 LEPOC|Ensembl=ENSLOCG00000009513.1|UniProtKB=W5MTC8 W5MTC8 PTHR13800:SF7 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 3 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262 transport#GO:0006810;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000018352.1|UniProtKB=W5NP94 W5NP94 PTHR47981:SF17 RAB FAMILY RAS-RELATED PROTEIN RAB-9B ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 cellular process#GO:0009987;lysosome organization#GO:0007040;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;transport#GO:0006810;lytic vacuole organization#GO:0080171;intracellular transport#GO:0046907;phagocytosis#GO:0006909;phagolysosome assembly#GO:0001845;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;endosomal transport#GO:0016197;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;vesicle fusion#GO:0006906;endocytosis#GO:0006897;organelle assembly#GO:0070925;vacuole organization#GO:0007033;cellular localization#GO:0051641;localization#GO:0051179 endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;late endosome#GO:0005770;cytoplasm#GO:0005737;vacuole#GO:0005773;lytic vacuole#GO:0000323;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000012185.1|UniProtKB=W5N2X5 W5N2X5 PTHR31774:SF0 PROTEIN SHISA-9-RELATED PROTEIN SHISA-6 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051;regulation of neuronal synaptic plasticity#GO:0048168;regulation of biological quality#GO:0065008 transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;cell leading edge#GO:0031252;neuron projection#GO:0043005;cell projection membrane#GO:0031253;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;neuron spine#GO:0044309;cell projection#GO:0042995;postsynapse#GO:0098794;dendritic spine#GO:0043197;signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 LEPOC|Ensembl=ENSLOCG00000013731.1|UniProtKB=W5N8H6 W5N8H6 PTHR16228:SF22 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008147.1|UniProtKB=W5MND4 W5MND4 PTHR23105:SF38 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER NHP2-LIKE PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA splicing, via transesterification reactions#GO:0000375;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;RNA splicing#GO:0008380;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;small nuclear ribonucleoprotein complex#GO:0030532;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012675.1|UniProtKB=W5N4N6 W5N4N6 PTHR12113:SF12 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 2 signaling receptor regulator activity#GO:0030545;binding#GO:0005488;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;signaling receptor inhibitor activity#GO:0030547 regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000013423.1|UniProtKB=W5N7E2 W5N7E2 PTHR46209:SF1 PX DOMAIN-CONTAINING PROTEIN SORTING NEXIN-11 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000010081.1|UniProtKB=W5MVC4 W5MVC4 PTHR46290:SF1 DI-N-ACETYLCHITOBIASE DI-N-ACETYLCHITOBIASE LEPOC|Ensembl=ENSLOCG00000001820.1|UniProtKB=W5M149 W5M149 PTHR45803:SF12 SOX100B SRY-BOX TRANSCRIPTION FACTOR 8A-RELATED DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 stem cell development#GO:0048864;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;mesenchyme development#GO:0060485;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;stem cell differentiation#GO:0048863;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;tissue development#GO:0009888;neural crest cell development#GO:0014032;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;mesenchymal cell differentiation#GO:0048762;neural crest cell differentiation#GO:0014033;morphogenesis of an epithelium#GO:0002009;animal organ development#GO:0048513;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000013762.1|UniProtKB=W5N8L1 W5N8L1 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003070.1|UniProtKB=W5M5F8 W5M5F8 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000829.1|UniProtKB=W5LXR9 W5LXR9 PTHR15362:SF7 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 2 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000006800.1|UniProtKB=W5MIM4 W5MIM4 PTHR20931:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 30 TETRATRICOPEPTIDE REPEAT PROTEIN 30 protein-containing complex binding#GO:0044877;binding#GO:0005488 organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoplasmic microtubule#GO:0005881;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;intraciliary transport particle#GO:0030990;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000012426.1|UniProtKB=W5N3U7 W5N3U7 PTHR11227:SF23 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 1 phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;polysaccharide catabolic process#GO:0000272;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;intracellular protein localization#GO:0008104;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;vacuole organization#GO:0007033;localization#GO:0051179;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;phagophore assembly site#GO:0000407 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002968.1|UniProtKB=W5M534 W5M534 PTHR46437:SF1 MORN REPEAT-CONTAINING PROTEIN 5 MORN REPEAT-CONTAINING PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000011376.1|UniProtKB=W5N021 W5N021 PTHR24355:SF27 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 5 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK5#P05940;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741 LEPOC|Ensembl=ENSLOCG00000015251.1|UniProtKB=W5NDQ8 W5NDQ8 PTHR11506:SF6 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 2 process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;cellular component disassembly#GO:0022411;cellular localization#GO:0051641;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;lysosomal transport#GO:0007041;protein targeting#GO:0006605;response to stimulus#GO:0050896;establishment of protein localization to vacuole#GO:0072666;cellular component organization#GO:0016043;protein localization to lysosome#GO:0061462;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular process#GO:0009987;autophagy#GO:0006914;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein targeting to vacuole#GO:0006623;response to stress#GO:0006950;protein metabolic process#GO:0019538;localization#GO:0051179;protein localization to vacuole#GO:0072665;protein-containing complex disassembly#GO:0032984;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to starvation#GO:0042594;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;transport#GO:0006810;vacuolar transport#GO:0007034;cellular response to nutrient levels#GO:0031669;intracellular transport#GO:0046907;autophagosome maturation#GO:0097352;cellular response to starvation#GO:0009267;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;response to nutrient levels#GO:0031667 intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;autophagosome#GO:0005776;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016263.1|UniProtKB=W5NHF2 W5NHF2 PTHR16517:SF2 TUBBY-RELATED TUBBY-RELATED PROTEIN 4 macromolecule localization#GO:0033036;protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104 cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004511.1|UniProtKB=W5MAJ8 W5MAJ8 PTHR11227:SF27 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;vacuole organization#GO:0007033;localization#GO:0051179;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;cellular component assembly#GO:0022607;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;phagophore assembly site#GO:0000407 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016777.1|UniProtKB=W5NJC8 W5NJC8 PTHR34488:SF1 SI:CH211-245H14.1-RELATED SI:CH211-245H14.1-RELATED LEPOC|Ensembl=ENSLOCG00000012671.1|UniProtKB=W5N4P5 W5N4P5 PTHR12444:SF1 PROTEIN EFR3 HOMOLOG CMP44E PROTEIN EFR3 HOMOLOG A protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008648.1|UniProtKB=W5MQ59 W5MQ59 PTHR13041:SF3 JTB PROTEIN-RELATED PROTEIN JTB mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000012486.1|UniProtKB=W5N410 W5N410 PTHR24342:SF16 SERINE/THREONINE-PROTEIN KINASE 17 SERINE_THREONINE-PROTEIN KINASE 17A kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000009577.1|UniProtKB=W5MTJ8 W5MTJ8 PTHR23257:SF992 SERINE-THREONINE PROTEIN KINASE SCAFFOLD PROTEIN ILK transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000003960.1|UniProtKB=W5M8M0 W5M8M0 PTHR21637:SF5 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED BTB_POZ DOMAIN-CONTAINING PROTEIN 10 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009482.1|UniProtKB=W5MT68 W5MT68 PTHR46608:SF3 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167 transport#GO:0006810;phagocytosis#GO:0006909;establishment of localization#GO:0051234;import into cell#GO:0098657;endocytosis#GO:0006897;localization#GO:0051179;apoptotic cell clearance#GO:0043277 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016377.1|UniProtKB=W5NHW7 W5NHW7 PTHR10159:SF45 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 6 protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of growth#GO:0040008;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000017133.1|UniProtKB=W5NKL8 W5NKL8 PTHR12619:SF28 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;glucose homeostasis#GO:0042593;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;chemical homeostasis#GO:0048878;developmental process#GO:0032502;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;carbohydrate homeostasis#GO:0033500;pancreas development#GO:0031016;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000003126.1|UniProtKB=W5M5M4 W5M5M4 PTHR22750:SF56 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009186.1|UniProtKB=W5MS45 W5MS45 PTHR24412:SF491 KELCH PROTEIN KELCH-LIKE PROTEIN 20 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 Apoptosis signaling pathway#P00006>Smac/Diablo#P00309 LEPOC|Ensembl=ENSLOCG00000013702.1|UniProtKB=W5N8D9 W5N8D9 PTHR46179:SF5 ZINC FINGER PROTEIN ZINC FINGER PROTEIN ZXDC transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000014863.1|UniProtKB=W5NCE4 W5NCE4 PTHR35441:SF2 CIRCADIAN-ASSOCIATED TRANSCRIPTIONAL REPRESSOR CIRCADIAN ASSOCIATED REPRESSOR OF TRANSCRIPTION A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;circadian rhythm#GO:0007623;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;rhythmic process#GO:0048511;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;circadian regulation of gene expression#GO:0032922;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012223.1|UniProtKB=W5N328 W5N328 PTHR31661:SF2 SIMILAR TO CDNA SEQUENCE BC052040 CDAN1-INTERACTING NUCLEASE 1 multicellular organismal-level homeostasis#GO:0048871;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;developmental process#GO:0032502;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376;cell development#GO:0048468;homeostatic process#GO:0042592;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000004450.1|UniProtKB=W5MAB1 W5MAB1 PTHR13199:SF12 GH03947P ATOS HOMOLOG PROTEIN B LEPOC|Ensembl=ENSLOCG00000005558.1|UniProtKB=W5ME97 W5ME97 PTHR14066:SF10 ATRIAL NATRIURETIC FACTOR PRECURSOR NATRIURETIC PEPTIDES B receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515 ribose phosphate biosynthetic process#GO:0046390;regulation of systemic arterial blood pressure#GO:0003073;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;regulation of biological quality#GO:0065008;nucleotide biosynthetic process#GO:0009165;regulation of blood pressure#GO:0008217;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;system process#GO:0003008;neuropeptide signaling pathway#GO:0007218;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;circulatory system process#GO:0003013;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000009530.1|UniProtKB=W5MTD9 W5MTD9 PTHR16523:SF6 PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014066.1|UniProtKB=W5N9M8 W5N9M8 PTHR15574:SF43 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 5 regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of lipid biosynthetic process#GO:0046890;negative regulation of metabolic process#GO:0009892;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001872.1|UniProtKB=W5M1A8 W5M1A8 PTHR12463:SF0 OXYGENASE-RELATED ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 contractile ring#GO:0070938;midbody#GO:0030496;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000015056.1|UniProtKB=W5ND23 W5ND23 PTHR31409:SF0 WASH COMPLEX SUBUNIT 4 WASH COMPLEX SUBUNIT 4 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010453.1|UniProtKB=W5MWT7 W5MWT7 PTHR48051:SF38 FAMILY NOT NAMED LEUCINE RICH REPEATS AND CALPONIN HOMOLOGY DOMAIN CONTAINING 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000013921.1|UniProtKB=W5N952 W5N952 PTHR24248:SF212 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000006113.1|UniProtKB=W5MG81 W5MG81 PTHR45638:SF16 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL BETA-1 channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;guanyl nucleotide binding#GO:0019001;gated channel activity#GO:0022836;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;purine ribonucleotide binding#GO:0032555;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076 cellular process#GO:0009987;homeostatic process#GO:0042592;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;transport#GO:0006810;tissue homeostasis#GO:0001894;monoatomic ion transport#GO:0006811;multicellular organismal-level homeostasis#GO:0048871;localization#GO:0051179;retina homeostasis#GO:0001895;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;transporter complex#GO:1990351;membrane protein complex#GO:0098796;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;transmembrane transporter complex#GO:1902495 ion channel#PC00133;ligand-gated ion channel#PC00141 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 LEPOC|Ensembl=ENSLOCG00000010646.1|UniProtKB=W5MXC6 W5MXC6 PTHR24241:SF89 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OXYTOCIN RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 regulation of biological quality#GO:0065008;cell communication#GO:0007154;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Oxytocin receptor mediated signaling pathway#P04391>Oxytocin Receptor#P04531 LEPOC|Ensembl=ENSLOCG00000000823.1|UniProtKB=W5LXR1 W5LXR1 PTHR23055:SF20 CALCIUM BINDING PROTEINS RECOVERIN ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Recoverin#P00756 LEPOC|Ensembl=ENSLOCG00000011516.1|UniProtKB=W5N0M1 W5N0M1 PTHR10082:SF42 INTEGRIN BETA SUBUNIT INTEGRIN BETA-4 protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;cell migration#GO:0016477;cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;cell junction#GO:0030054;anchoring junction#GO:0070161;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 LEPOC|Ensembl=ENSLOCG00000010440.1|UniProtKB=W5MWN4 W5MWN4 PTHR24070:SF189 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE NRAS ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552;Ras Pathway#P04393>Ras#P04547;Integrin signalling pathway#P00034>Ras#P00916;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;PI3 kinase pathway#P00048>Ras#P01182;B cell activation#P00010>Ras#P00376;Angiogenesis#P00005>Ras#P00238;p53 pathway feedback loops 2#P04398>Ras#P04651;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;FGF signaling pathway#P00021>Ras#P00633;Interleukin signaling pathway#P00036>Ras#P00977;T cell activation#P00053>Ras#P01306 LEPOC|Ensembl=ENSLOCG00000004361.1|UniProtKB=W5MA03 W5MA03 PTHR16184:SF6 ELONGATOR COMPLEX PROTEIN 6 ELONGATOR COMPLEX PROTEIN 6 protein-containing complex#GO:0032991;elongator holoenzyme complex#GO:0033588;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000007658.1|UniProtKB=W5MLN2 W5MLN2 PTHR28666:SF2 TRANSMEMBRANE PROTEIN 240 TRANSMEMBRANE PROTEIN 240-RELATED LEPOC|Ensembl=ENSLOCG00000010219.1|UniProtKB=W5MVV1 W5MVV1 PTHR24067:SF246 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 B transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;response to stimulus#GO:0050896;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;membraneless organelle#GO:0043228;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;chromatin#GO:0000785;chromosome#GO:0005694 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000017080.1|UniProtKB=W5NKF1 W5NKF1 HDHD5 PTHR14269:SF17 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING 5 metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011019.1|UniProtKB=W5MYS4 W5MYS4 PTHR40710:SF1 RIKEN CDNA E230025N22 GENE RIKEN CDNA E230025N22 GENE LEPOC|Ensembl=ENSLOCG00000008882.1|UniProtKB=W5MR16 W5MR16 PTHR13742:SF36 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-ASSOCIATED PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;regulation of mitotic cell cycle#GO:0007346;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell cycle process#GO:0010564;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;negative regulation of cell cycle#GO:0045786;neuron differentiation#GO:0030182;regulation of cell cycle#GO:0051726;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;neuron development#GO:0048666;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway feedback loops 2#P04398>Rb#P04654 LEPOC|Ensembl=ENSLOCG00000012065.1|UniProtKB=W5N2L3 W5N2L3 PTHR11453:SF12 ANION EXCHANGE PROTEIN BAND 3 ANION TRANSPORT PROTEIN active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108 biological regulation#GO:0065007;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000007690.1|UniProtKB=W5MLT2 W5MLT2 PTHR22776:SF9 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PLASMOLIPIN multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;myelination#GO:0042552;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;signaling#GO:0023052;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;myelin sheath#GO:0043209;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010966.1|UniProtKB=W5MYK1 W5MYK1 PTHR11947:SF22 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 4, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of biosynthetic process#GO:0009889;regulation of carbohydrate metabolic process#GO:0006109;cellular response to insulin stimulus#GO:0032869;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;regulation of lipid metabolic process#GO:0019216;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to chemical stimulus#GO:0070887;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008162.1|UniProtKB=W5MNH3 W5MNH3 PTHR11851:SF226 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585 transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275;endopeptidase complex#GO:1905369;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;membrane-enclosed lumen#GO:0031974;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015909.1|UniProtKB=W5NG38 W5NG38 PTHR11042:SF194 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011280.1|UniProtKB=W5MZQ1 W5MZQ1 PTHR24028:SF296 CADHERIN-87A PROTOCADHERIN 1 GAMMA 11 PRECURSOR-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002065.1|UniProtKB=W5M1Y6 W5M1Y6 PTHR15099:SF2 PROTEIN PM1 TRANSMEMBRANE PROTEIN 11, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;membrane organization#GO:0061024 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000015054.1|UniProtKB=W5ND17 W5ND17 PTHR10122:SF20 CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;organelle membrane#GO:0031090;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000004838.1|UniProtKB=W5MBQ2 W5MBQ2 PTHR45617:SF162 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING 32 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014385.1|UniProtKB=W5NAQ2 W5NAQ2 PTHR24026:SF38 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 3 animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;axon development#GO:0061564;cellular process#GO:0009987;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667 anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000006035.1|UniProtKB=W5MFY1 W5MFY1 PTHR14256:SF5 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE HYPOXIA ASSOCIATED SUBUNIT FA4L2 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003130.1|UniProtKB=W5M5N6 W5M5N6 PTHR10336:SF51 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ETA-1 phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;signaling#GO:0023052;cell-cell signaling#GO:0007267;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530 LEPOC|Ensembl=ENSLOCG00000011728.1|UniProtKB=W5N1B2 W5N1B2 PTHR45723:SF5 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE_THREONINE-PROTEIN KINASE RIO1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;preribosome#GO:0030684 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005732.1|UniProtKB=W5MEW9 W5MEW9 PTHR24174:SF20 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 CASKIN-1 ISOFORM X1 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000855.1|UniProtKB=W5LXU7 W5LXU7 PTHR12002:SF108 CLAUDIN CLAUDIN cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000011703.1|UniProtKB=W5N176 W5N176 PTHR13378:SF1 REGULATOR COMPLEX PROTEIN LAMTOR3 RAGULATOR COMPLEX PROTEIN LAMTOR3 positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of TORC1 signaling#GO:1904263 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005707.1|UniProtKB=W5MEV3 W5MEV3 PTHR46396:SF1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011875.1|UniProtKB=W5N1U8 W5N1U8 PTHR45962:SF7 N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D1 N-FATTY-ACYL-AMINO ACID SYNTHASE_HYDROLASE PM20D1.1-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005290.1|UniProtKB=W5MDB6 W5MDB6 PTHR24271:SF97 KALLIKREIN-RELATED MAST CELL PROTEASE 2 ISOFORM X1 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000012841.1|UniProtKB=W5N5A3 W5N5A3 PTHR24027:SF428 CADHERIN-23 CADHERIN-10 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 anatomical structure development#GO:0048856;synaptic membrane adhesion#GO:0099560;synapse organization#GO:0050808;cell adhesion#GO:0007155;cell motility#GO:0048870;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular process#GO:0009987 membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;anchoring junction#GO:0070161;adherens junction#GO:0005912 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000006742.1|UniProtKB=W5MID5 W5MID5 PTHR17614:SF13 ZINC FINGER-CONTAINING ZINC FINGER PROTEIN 804A intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015865.1|UniProtKB=W5NFX3 W5NFX3 PTHR10901:SF12 TROPOMODULIN LEIOMODIN-2 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle contraction#GO:0006936;developmental process#GO:0032502;actin filament organization#GO:0007015;system process#GO:0003008;cellular developmental process#GO:0048869;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;M band#GO:0031430;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;A band#GO:0031672 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000007294.1|UniProtKB=W5MKC4 W5MKC4 PTHR12861:SF3 TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004600.1|UniProtKB=W5MAW1 W5MAW1 PTHR24384:SF193 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED PR_SET DOMAIN 15 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000007461.1|UniProtKB=W5MKZ2 W5MKZ2 PTHR35263:SF1 TESTIS-EXPRESSED PROTEIN 49 SPERM MICROTUBULE INNER PROTEIN 11 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;microtubule#GO:0005874;cilium#GO:0005929;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;axonemal doublet microtubule#GO:0097545;supramolecular complex#GO:0099080;A axonemal microtubule#GO:0097649;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000005359.1|UniProtKB=W5MDJ8 W5MDJ8 PTHR10671:SF9 EPITHELIAL MEMBRANE PROTEIN-RELATED LENS FIBER MEMBRANE INTRINSIC PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000008780.1|UniProtKB=W5MQN0 W5MQN0 PTHR19969:SF12 SH2-SH3 ADAPTOR PROTEIN-RELATED CYTOPLASMIC PROTEIN NCK2 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090 positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of translation#GO:0045727;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of apoptotic signaling pathway#GO:2001233;response to endoplasmic reticulum stress#GO:0034976;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell motility#GO:0048870;ephrin receptor signaling pathway#GO:0048013;regulation of response to endoplasmic reticulum stress#GO:1905897;cellular response to stimulus#GO:0051716;regulation of intrinsic apoptotic signaling pathway#GO:2001242;positive regulation of signal transduction#GO:0009967;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;negative regulation of signal transduction#GO:0009968;positive regulation of macromolecule metabolic process#GO:0010604;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;regulation of cellular response to stress#GO:0080135;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of signaling#GO:0023056;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Nck#P01147;Angiogenesis#P00005>Nck#P00215;T cell activation#P00053>nck#P01314 LEPOC|Ensembl=ENSLOCG00000013025.1|UniProtKB=W5N5Z3 W5N5Z3 PTHR22625:SF7 PLEXIN PLEXIN-D1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component assembly#GO:0022607;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;regulation of axonogenesis#GO:0050770;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of cell shape#GO:0008360;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of nervous system development#GO:0051962;synapse assembly#GO:0007416;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;positive regulation of axonogenesis#GO:0050772;regulation of biological quality#GO:0065008;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;negative regulation of cell adhesion#GO:0007162;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;system development#GO:0048731 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015016.1|UniProtKB=W5NCX8 W5NCX8 PTHR12232:SF5 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN ADAPTER SH3BGRL ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-RNA adaptor activity#GO:0140517;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of translational initiation#GO:0006446;protein catabolic process#GO:0030163;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000012152.1|UniProtKB=W5N2T8 W5N2T8 PTHR11571:SF141 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE P transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364 sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009417.1|UniProtKB=W5MSX7 W5MSX7 PTHR15191:SF7 PROTEIN CBG20567 PTTG1 INTERACTING PROTEIN B PRECURSOR protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001887.1|UniProtKB=W5M1C9 W5M1C9 PTHR13070:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;lyase activity#GO:0016829;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101 RNA splicing#GO:0008380;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000004139.1|UniProtKB=W5M994 W5M994 PTHR16515:SF19 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 14 ISOFORM X1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000011551.1|UniProtKB=W5N0N2 W5N0N2 PTHR46722:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;biological regulation#GO:0065007 membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000015002.1|UniProtKB=W5NCW2 W5NCW2 PTHR22978:SF30 B-CELL TRANSLOCATION GENE PROTEIN BTG1 biological regulation#GO:0065007;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell population proliferation#GO:0008285;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000007129.1|UniProtKB=W5MJS7 W5MJS7 PTHR24033:SF151 EGF-LIKE DOMAIN-CONTAINING PROTEIN NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000011647.1|UniProtKB=W5N106 W5N106 PTHR11920:SF347 GUANYLYL CYCLASE GUANYLYL CYCLASE C phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;lyase activity#GO:0016829 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanylate cyclase#PC00114;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000011150.1|UniProtKB=W5MZ92 W5MZ92 PTHR16189:SF0 TRANSMEMBRANE PROTEIN 104-RELATED SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 12-RELATED LEPOC|Ensembl=ENSLOCG00000008445.1|UniProtKB=W5MPG8 W5MPG8 PTHR10048:SF122 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE BETA phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 animal gross anatomical part developmental process#GO:0160108;phosphatidylinositol phosphate biosynthetic process#GO:0046854;ear development#GO:0043583;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;metabolic process#GO:0008152;animal organ development#GO:0048513;cellular process#GO:0009987;signal transduction#GO:0007165;glycerophospholipid metabolic process#GO:0006650;organophosphate biosynthetic process#GO:0090407;anatomical structure development#GO:0048856;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;sensory organ development#GO:0007423;lipid metabolic process#GO:0006629;developmental process#GO:0032502;glycerophospholipid biosynthetic process#GO:0046474;inner ear development#GO:0048839;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000001122.1|UniProtKB=W5LYR4 W5LYR4 PTHR23193:SF5 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR ENVELOPE PORE MEMBRANE PROTEIN POM 121C-RELATED molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142;structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein transport#GO:0006886;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;protein import into nucleus#GO:0006606;nuclear export#GO:0051168;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007965.1|UniProtKB=W5MMR4 W5MMR4 PTHR16134:SF163 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 8 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014879.1|UniProtKB=W5NCG5 W5NCG5 PTHR31882:SF9 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3 INTERACTING PROTEIN 1 response to lipopolysaccharide#GO:0032496;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;cellular response to molecule of bacterial origin#GO:0071219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;response to bacterium#GO:0009617;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216 LEPOC|Ensembl=ENSLOCG00000010349.1|UniProtKB=W5MWC5 W5MWC5 PTHR24340:SF101 HOMEOBOX PROTEIN NKX H6 FAMILY HOMEOBOX 4 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000007766.1|UniProtKB=W5MM32 W5MM32 AGO2 PTHR22891:SF59 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-2 single-stranded RNA binding#GO:0003727;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000018221.1|UniProtKB=W5NNW3 W5NNW3 PTHR17068:SF3 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER HOMOLOG LEPOC|Ensembl=ENSLOCG00000007801.1|UniProtKB=W5MM60 W5MM60 PTHR32297:SF1 SODIUM CHANNEL MODIFIER 1 SODIUM CHANNEL MODIFIER 1 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000011287.1|UniProtKB=W5MZR7 W5MZR7 PTHR43721:SF9 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 1 translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000008450.1|UniProtKB=W5MPG9 W5MPG9 PTHR31449:SF3 UPF0598 PROTEIN C8ORF82 UPF0598 PROTEIN C8ORF82 LEPOC|Ensembl=ENSLOCG00000005019.1|UniProtKB=W5MCD3 W5MCD3 PTHR44167:SF34 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED DOUBLECORTIN-LIKE AND CAM KINASE-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005950.1|UniProtKB=W5MFN3 W5MFN3 PTHR13067:SF2 CASPASE-ACTIVATED DNASE DNAATION FACTOR-RELATED PROTEIN 4 DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;programmed cell death#GO:0012501;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>CAD#P00618 LEPOC|Ensembl=ENSLOCG00000017962.1|UniProtKB=W5NN56 W5NN56 PTHR48043:SF63 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 LEPOC|Ensembl=ENSLOCG00000013554.1|UniProtKB=W5N7W2 W5N7W2 PTHR11254:SF300 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF2 protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 negative regulation of signaling#GO:0023057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;negative regulation of BMP signaling pathway#GO:0030514;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 TGF-beta signaling pathway#P00052>Smurfs#P01279;Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000018218.1|UniProtKB=W5NNW0 W5NNW0 PTHR24235:SF20 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 2 peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007448.1|UniProtKB=W5MKX4 W5MKX4 PTHR46987:SF6 NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN R-SPONDIN-4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000018006.1|UniProtKB=W5NN98 W5NN98 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000008448.1|UniProtKB=W5MPH5 W5MPH5 PTHR46474:SF1 TWO PORE CALCIUM CHANNEL PROTEIN 1 TWO PORE CHANNEL PROTEIN 1 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vesicle membrane#GO:0012506;lysosomal membrane#GO:0005765 ion channel#PC00133 CCKR signaling map#P06959>TPC1/2#P07209 LEPOC|Ensembl=ENSLOCG00000011757.1|UniProtKB=W5N1E6 W5N1E6 PTHR16271:SF11 F-BOX ONLY PROTEIN 34/46 FAMILY MEMBER F-BOX ONLY PROTEIN 34 LEPOC|Ensembl=ENSLOCG00000014758.1|UniProtKB=W5NC12 W5NC12 PTHR45951:SF2 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED HOMOLOG 2 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000001180.1|UniProtKB=W5LYX1 W5LYX1 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016738.1|UniProtKB=W5NJ77 W5NJ77 PTHR17005:SF3 MALE-ENHANCED ANTIGEN-1 MALE-ENHANCED ANTIGEN 1 LEPOC|Ensembl=ENSLOCG00000010264.1|UniProtKB=W5MW08 W5MW08 PTHR31770:SF12 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER TAFA CHEMOKINE LIKE FAMILY MEMBER 3 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000015985.1|UniProtKB=W5NGC3 W5NGC3 PTHR11106:SF104 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED ADP-RIBOSE GLYCOHYDROLASE MACROD2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on a protein#GO:0140096 nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;cellular response to stimulus#GO:0051716;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine nucleoside metabolic process#GO:0042278;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000014651.1|UniProtKB=W5NBM8 W5NBM8 PTHR22576:SF38 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1-LIKE cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014675.1|UniProtKB=W5NBQ8 W5NBQ8 PTHR12552:SF14 OLIGOPHRENIN 1 OLIGOPHRENIN-1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000002473.1|UniProtKB=W5M3E4 W5M3E4 PTHR12943:SF5 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UBIQUITIN-LIKE DOMAIN MEMBER 2 PROTEIN intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950 LEPOC|Ensembl=ENSLOCG00000008870.1|UniProtKB=W5MQY8 W5MQY8 PTHR22192:SF17 SPERIOLIN SPERIOLIN C-TERMINAL DOMAIN-CONTAINING PROTEIN intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000000584.1|UniProtKB=W5LWZ4 W5LWZ4 EIF2C4 PTHR22891:SF26 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-4 RNA nuclease activity#GO:0004540;single-stranded RNA binding#GO:0003727;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000016017.1|UniProtKB=W5NGH1 W5NGH1 PTHR12826:SF13 RIBONUCLEASE Y RNA-BINDING PROTEIN PNO1 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000018195.1|UniProtKB=W5NNT7 W5NNT7 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016031.1|UniProtKB=W5NGI8 W5NGI8 PTHR10824:SF36 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COA THIOESTERASE 14 PRECURSOR-RELATED hydrolase activity#GO:0016787;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790 oxoacid metabolic process#GO:0043436;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000012812.1|UniProtKB=W5N553 W5N553 PTHR21514:SF0 AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cellular anatomical structure#GO:0110165;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 LEPOC|Ensembl=ENSLOCG00000014027.1|UniProtKB=W5N9I7 W5N9I7 PTHR12372:SF2 PECANEX PECANEX-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000011605.1|UniProtKB=W5N0V1 W5N0V1 PTHR46606:SF1 SHOOTIN-1 SHOOTIN-1 ISOFORM X1 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;system development#GO:0048731;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of neuron migration#GO:2001222;positive regulation of locomotion#GO:0040017;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501 site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;growth cone#GO:0030426;axonal growth cone#GO:0044295;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell leading edge#GO:0031252 LEPOC|Ensembl=ENSLOCG00000006894.1|UniProtKB=W5MIX7 W5MIX7 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016125.1|UniProtKB=W5NGW0 W5NGW0 PTHR32005:SF1 TRANSMEMBRANE PROTEIN 178B-RELATED TRANSMEMBRANE PROTEIN 178B membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010640.1|UniProtKB=W5MXB9 W5MXB9 PTHR23248:SF38 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;endomembrane system organization#GO:0010256;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;lipid localization#GO:0010876;plasma membrane organization#GO:0007009;localization#GO:0051179;regulation of biological quality#GO:0065008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005926.1|UniProtKB=W5MFJ5 W5MFJ5 PTHR10036:SF13 CD59 GLYCOPROTEIN MAC-INHIBITORY PROTEIN LEPOC|Ensembl=ENSLOCG00000001030.1|UniProtKB=W5LYF0 W5LYF0 PTHR47115:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 183 COILED-COIL DOMAIN-CONTAINING PROTEIN 183 LEPOC|Ensembl=ENSLOCG00000005656.1|UniProtKB=W5MEM0 W5MEM0 PTHR14926:SF1 M-PHASE PHOSPHOPROTEIN 9 M-PHASE PHOSPHOPROTEIN 9 centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000004243.1|UniProtKB=W5M9L4 W5M9L4 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004212.1|UniProtKB=W5M9I1 W5M9I1 PTHR23136:SF10 TAX1-BINDING PROTEIN 3-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 6 LEPOC|Ensembl=ENSLOCG00000003635.1|UniProtKB=W5M7F0 W5M7F0 PTHR14057:SF10 TRANSCRIPTION FACTOR ONECUT ONE CUT DOMAIN FAMILY MEMBER 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015048.1|UniProtKB=W5ND22 W5ND22 PTHR12844:SF12 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS TESTIS EXPRESSED GENE 16 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013648.1|UniProtKB=W5N872 W5N872 PTHR10388:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR 1 ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488;nucleic acid binding#GO:0003676;translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000016523.1|UniProtKB=W5NIE8 W5NIE8 PTHR12486:SF5 APRATAXIN-RELATED ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006953.1|UniProtKB=W5MJ54 W5MJ54 PTHR23277:SF106 NECTIN-RELATED NECTIN 1A-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011310.1|UniProtKB=W5MZU0 W5MZU0 PTHR11346:SF198 GALECTIN GALECTIN binding#GO:0005488;laminin binding#GO:0043236;protein binding#GO:0005515;extracellular matrix binding#GO:0050840;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000005887.1|UniProtKB=W5MFF2 W5MFF2 PTHR12374:SF85 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-ALPHA chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338 intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;SAGA-type complex#GO:0070461;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006378.1|UniProtKB=W5MH42 W5MH42 PTHR21052:SF0 SPERMATOGENESIS ASSOCIATED 11-RELATED RNA DEMETHYLASE ALKBH7, MITOCHONDRIAL oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010675.1|UniProtKB=W5MXH0 W5MXH0 PTHR23077:SF12 AAA-FAMILY ATPASE PEROXISOMAL ATPASE PEX1 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887 organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;cellular component organization#GO:0016043;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;peroxisomal transport#GO:0043574;peroxisome organization#GO:0007031 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;cytosol#GO:0005829;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015230.1|UniProtKB=W5NDN5 W5NDN5 PTHR10372:SF25 PLAKOPHILLIN-RELATED PLAKOPHILIN-2 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;heart development#GO:0007507;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell-cell adhesion#GO:0098609;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;intermediate filament bundle assembly#GO:0045110;protein localization to cell periphery#GO:1990778;intermediate filament cytoskeleton organization#GO:0045104;circulatory system development#GO:0072359;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cellular localization#GO:0051641;cell adhesion#GO:0007155;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell junction organization#GO:0034330;protein localization to plasma membrane#GO:0072659;system development#GO:0048731;supramolecular fiber organization#GO:0097435;localization#GO:0051179;anatomical structure development#GO:0048856;localization within membrane#GO:0051668 cell periphery#GO:0071944;nucleus#GO:0005634;cell-cell junction#GO:0005911;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cell-cell contact zone#GO:0044291;adherens junction#GO:0005912;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intercalated disc#GO:0014704;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 intermediate filament binding protein#PC00130;cytoskeletal protein#PC00085;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000008345.1|UniProtKB=W5MP24 W5MP24 PTHR24173:SF23 ANKYRIN REPEAT CONTAINING UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;negative regulation of intracellular signal transduction#GO:1902532;intrinsic apoptotic signaling pathway#GO:0097193;negative regulation of cell communication#GO:0010648;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;negative regulation of biological process#GO:0048519;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of response to external stimulus#GO:0032101;negative regulation of signal transduction#GO:0009968;negative regulation of response to external stimulus#GO:0032102;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013979.1|UniProtKB=W5N9C2 W5N9C2 PTHR12659:SF2 RHO-TYPE GTPASE ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 7 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of signaling#GO:0023051;actin filament-based process#GO:0030029;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cell communication#GO:0010646;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023 membrane microdomain#GO:0098857;anchoring junction#GO:0070161;cell junction#GO:0030054;membrane#GO:0016020;membrane raft#GO:0045121;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000000939.1|UniProtKB=W5LY40 W5LY40 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010369.1|UniProtKB=W5MWE6 W5MWE6 PTHR24247:SF212 5-HYDROXYTRYPTAMINE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018268.1|UniProtKB=W5NP10 W5NP10 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006475.1|UniProtKB=W5MHF9 W5MHF9 PTHR10336:SF84 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN INACTIVE PHOSPHOLIPASE C-LIKE PROTEIN 2 lipase activity#GO:0016298;hydrolase activity#GO:0016787;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 cell communication#GO:0007154;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412 LEPOC|Ensembl=ENSLOCG00000004646.1|UniProtKB=W5MB09 W5MB09 PTHR15829:SF2 PROTEIN KINASE PKN/PRK1, EFFECTOR RHO FAMILY-INTERACTING CELL POLARIZATION REGULATOR 2 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000006146.1|UniProtKB=W5MGB6 W5MGB6 PTHR22589:SF16 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016936.1|UniProtKB=W5NJX9 W5NJX9 PTHR32428:SF4 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED PROLINE-RICH PROTEIN 5 protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;TORC2 signaling#GO:0038203;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;TOR signaling#GO:0031929;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 protein-containing complex#GO:0032991;TOR complex#GO:0038201;intracellular protein-containing complex#GO:0140535 PDGF signaling pathway#P00047>Rho#P01174;VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520 LEPOC|Ensembl=ENSLOCG00000010268.1|UniProtKB=W5MW31 W5MW31 PTHR46089:SF3 ALSIN HOMOLOG ALSIN enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000011978.1|UniProtKB=W5N277 W5N277 PTHR32083:SF0 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58 intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004129.1|UniProtKB=W5M988 W5M988 PTHR11861:SF1 MELANOCYTE PROTEIN PMEL 17-RELATED MELANOCYTE PROTEIN PMEL cellular pigmentation#GO:0033059;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;pigmentation#GO:0043473;melanosome organization#GO:0032438 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;melanosome#GO:0042470;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000018224.1|UniProtKB=W5NNW6 W5NNW6 PTHR23226:SF438 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 436 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000017644.1|UniProtKB=W5NM90 W5NM90 PTHR26451:SF869 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 530-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005668.1|UniProtKB=W5MEN4 W5MEN4 PTHR11955:SF67 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, LIVER-RELATED organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;fatty acid binding#GO:0005504 lipid transport#GO:0006869;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000003119.1|UniProtKB=W5M5N0 W5M5N0 LONP1 PTHR43718:SF2 LON PROTEASE LON PROTEASE HOMOLOG, MITOCHONDRIAL DNA binding#GO:0003677;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cellular process#GO:0009987;organelle organization#GO:0006996;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007126.1|UniProtKB=W5MJR9 W5MJR9 PTHR12622:SF5 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX4 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005957.1|UniProtKB=W5MFN5 W5MFN5 PTHR13366:SF0 MALARIA ANTIGEN-RELATED HEAT REPEAT-CONTAINING PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000012225.1|UniProtKB=W5N329 W5N329 PTHR22738:SF9 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 5 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016952.1|UniProtKB=W5NJZ7 W5NJZ7 PTHR46105:SF8 AGAP004733-PA TRANSCRIPTION REGULATOR PROTEIN BACH2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000007739.1|UniProtKB=W5MLY5 W5MLY5 PTHR14815:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 17 DDB1- AND CUL4-ASSOCIATED FACTOR 17 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 LEPOC|Ensembl=ENSLOCG00000015872.1|UniProtKB=W5NFY2 W5NFY2 PTHR21074:SF0 IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN IQ MOTIF AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;secretory vesicle#GO:0099503;endomembrane system#GO:0012505;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000007615.1|UniProtKB=W5MLI3 W5MLI3 PTHR10747:SF4 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE3 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 P53-like transcription factor#PC00253;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000005121.1|UniProtKB=W5MCR4 W5MCR4 PTHR44549:SF1 ENDOTHELIAL CELL-SELECTIVE ADHESION MOLECULE ENDOTHELIAL CELL-SELECTIVE ADHESION MOLECULE cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515 cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009452.1|UniProtKB=W5MT29 W5MT29 PTHR23068:SF4 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED PWWP DOMAIN-CONTAINING PROTEIN 2A protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA methyltransferase#PC00013 LEPOC|Ensembl=ENSLOCG00000014508.1|UniProtKB=W5NB48 W5NB48 PTHR13944:SF18 AGAP007712-PA A-KINASE ANCHOR PROTEIN 13 molecular function regulator activity#GO:0098772;structural molecule activity#GO:0005198;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;MAP kinase scaffold activity#GO:0005078;protein complex scaffold activity#GO:0140378;molecular adaptor activity#GO:0060090;enzyme regulator activity#GO:0030234;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;positive regulation of response to stimulus#GO:0048584;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of signaling#GO:0023056 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membrane#GO:0016020;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000018279.1|UniProtKB=W5NP21 W5NP21 PTHR20855:SF96 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER VII, A transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;lipid binding#GO:0008289;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;steroid binding#GO:0005496;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;response to chemical#GO:0042221;response to lipid#GO:0033993;response to endogenous stimulus#GO:0009719;response to steroid hormone#GO:0048545;response to hormone#GO:0009725 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009519.1|UniProtKB=W5MTC4 W5MTC4 PTHR12473:SF8 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED LEPOC|Ensembl=ENSLOCG00000012997.1|UniProtKB=W5N5V2 W5N5V2 PTHR24031:SF91 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX24 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015261.1|UniProtKB=W5NDS1 W5NDS1 PTHR45636:SF6 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-8 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006917.1|UniProtKB=W5MJ01 W5MJ01 PTHR12015:SF108 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 20 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 LEPOC|Ensembl=ENSLOCG00000006351.1|UniProtKB=W5MH11 W5MH11 PTHR11802:SF434 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE CARBOXYPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000012966.1|UniProtKB=W5N5Q9 W5N5Q9 PTHR21245:SF6 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 47 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014671.1|UniProtKB=W5NBQ3 W5NBQ3 PTHR34252:SF1 UPF0705 PROTEIN C11ORF49 CENTRIOLAR SATELLITE-ASSOCIATED TUBULIN POLYGLUTAMYLASE COMPLEX REGULATOR 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 LEPOC|Ensembl=ENSLOCG00000003747.1|UniProtKB=W5M7V7 W5M7V7 PTHR13325:SF3 PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASE metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to endoplasmic reticulum stress#GO:1905897;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cellular response to stress#GO:0080135;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;proteolysis#GO:0006508 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014537.1|UniProtKB=W5NB87 W5NB87 PTHR19328:SF58 HEDGEHOG-INTERACTING PROTEIN HHIP-LIKE PROTEIN 1 ISOFORM X1 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005693.1|UniProtKB=W5MER9 W5MER9 PTHR15897:SF2 ANKYRIN REPEAT AND MYND DOMAIN PROTEIN 1 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000014259.1|UniProtKB=W5NA95 W5NA95 PTHR12731:SF1 TRANSLOCON-ASSOCIATED PROTEIN, DELTA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT DELTA cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000003115.1|UniProtKB=W5M5M9 W5M5M9 PTHR24269:SF26 KREMEN PROTEIN KRINGLE-CONTAINING PROTEIN MARKING THE EYE AND THE NOSE transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016724.1|UniProtKB=W5NJ53 W5NJ53 PTHR46956:SF1 NUCLEOSIDE DIPHOSPHATE KINASE 6 NUCLEOSIDE DIPHOSPHATE KINASE 6, MITOCHONDRIAL phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824 negative regulation of mitotic cell cycle#GO:0045930;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of mitotic nuclear division#GO:0045839;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic cell cycle#GO:0007346;regulation of cell growth#GO:0001558;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;negative regulation of cell growth#GO:0030308;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 LEPOC|Ensembl=ENSLOCG00000011904.1|UniProtKB=W5N1Y0 W5N1Y0 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 ISOFORM X1 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000010795.1|UniProtKB=W5MXW7 W5MXW7 PTHR10083:SF352 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED TISSUE FACTOR PATHWAY INHIBITOR 2 serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017812.1|UniProtKB=W5NMQ7 W5NMQ7 PTHR17602:SF4 RIBOSOME BIOGENESIS REGULATORY PROTEIN RIBOSOME BIOGENESIS REGULATORY PROTEIN HOMOLOG cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014665.1|UniProtKB=W5NBP2 W5NBP2 PTHR24238:SF57 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 83 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013878.1|UniProtKB=W5N913 W5N913 PTHR10353:SF336 GLYCOSYL HYDROLASE LACTASE-LIKE PROTEIN glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 hydrolase#PC00121;glycosidase#PC00110;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003392.1|UniProtKB=W5M6L4 W5M6L4 PTHR10751:SF100 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 1 ISOFORM X1-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 G-protein#PC00020;heterotrimeric G-protein#PC00117 LEPOC|Ensembl=ENSLOCG00000007838.1|UniProtKB=W5MMA3 W5MMA3 PTHR14297:SF8 MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER ENDOPLASMIC RETICULUM MEMBRANE ADAPTER PROTEIN XK molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000006075.1|UniProtKB=W5MG28 W5MG28 PTHR45620:SF21 PDF RECEPTOR-LIKE PROTEIN-RELATED CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008687.1|UniProtKB=W5MQA9 W5MQA9 PTHR16253:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 22 TETRATRICOPEPTIDE REPEAT PROTEIN 22 LEPOC|Ensembl=ENSLOCG00000014691.1|UniProtKB=W5NBS7 W5NBS7 PTHR45776:SF3 MIP04163P TRANSCRIPTION FACTOR E3 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008165.1|UniProtKB=W5MNF1 W5MNF1 CNN3 PTHR46756:SF4 TRANSGELIN CALPONIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 microtubule bundle formation#GO:0001578;actin filament-based process#GO:0030029;regulation of microtubule-based process#GO:0032886;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;intracellular protein localization#GO:0008104;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;protein localization to microtubule cytoskeleton#GO:0072698 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432;microtubule#GO:0005874;microtubule end#GO:1990752;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;stress fiber#GO:0001725;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;actomyosin#GO:0042641;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000000067.1|UniProtKB=W5LVB9 W5LVB9 PTHR46780:SF21 PROTEIN EVA-1 D-GALACTOSIDE-SPECIFIC LECTIN ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000008797.1|UniProtKB=W5MQP8 W5MQP8 PTHR11852:SF4 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE LITTLE ELONGATION COMPLEX SUBUNIT 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase III#GO:0042796;nucleic acid biosynthetic process#GO:0141187;snRNA transcription#GO:0009301;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase II#GO:0042795;transcription by RNA polymerase III#GO:0006383;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014253.1|UniProtKB=W5NA88 W5NA88 PTHR45827:SF3 SORTING NEXIN SORTING NEXIN-33 ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;membrane invagination#GO:0010324;endocytosis#GO:0006897;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;cellular localization#GO:0051641;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;plasma membrane organization#GO:0007009;cytokinesis#GO:0000910;cytokinetic process#GO:0032506 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008376.1|UniProtKB=W5MP68 W5MP68 PTHR24366:SF129 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT CONTAINING 24 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000004306.1|UniProtKB=W5M9T9 W5M9T9 PTHR10867:SF32 NNMT/PNMT/TEMT FAMILY MEMBER MGC107884 PROTEIN N-methyltransferase activity#GO:0008170;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 LEPOC|Ensembl=ENSLOCG00000012600.1|UniProtKB=W5N4F4 W5N4F4 PTHR46880:SF6 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 385C LEPOC|Ensembl=ENSLOCG00000001570.1|UniProtKB=W5M0A0 W5M0A0 PTHR22968:SF25 PROTEIN KINASE C, MU PROTEIN KINASE D4 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011777.1|UniProtKB=W5N1H2 W5N1H2 PTHR11860:SF120 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 5-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007286.1|UniProtKB=W5MKB3 W5MKB3 PTHR15564:SF2 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;cell differentiation#GO:0030154;central nervous system development#GO:0007417;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;generation of neurons#GO:0048699;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;negative regulation of mitotic cell cycle#GO:0045930;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;nervous system development#GO:0007399;response to chemical#GO:0042221;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;negative regulation of cell cycle#GO:0045786;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;cellular developmental process#GO:0048869 dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;cell body#GO:0044297;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000003270.1|UniProtKB=W5M663 W5M663 PTHR11958:SF67 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 4 solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;solute:monoatomic cation symporter activity#GO:0015294;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;L-glutamate import#GO:0051938;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;acidic amino acid transport#GO:0015800;carboxylic acid transport#GO:0046942 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 LEPOC|Ensembl=ENSLOCG00000007507.1|UniProtKB=W5ML59 W5ML59 PTHR45668:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 1 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000013041.1|UniProtKB=W5N613 W5N613 PTHR11339:SF374 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED ZONADHESIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000007421.1|UniProtKB=W5MKZ4 W5MKZ4 PTHR10629:SF61 CYTOSINE-SPECIFIC METHYLTRANSFERASE DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA methyltransferase#PC00013 LEPOC|Ensembl=ENSLOCG00000007809.1|UniProtKB=W5MM78 W5MM78 PTHR12893:SF1 GOLGI REASSEMBLY STACKING PROTEIN GRASP GOLGI REASSEMBLY-STACKING PROTEIN 2 organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000014058.1|UniProtKB=W5N9L7 W5N9L7 PTHR23339:SF123 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE DOMAIN-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004901.1|UniProtKB=W5MBY3 W5MBY3 PTHR11909:SF7 CASEIN KINASE-RELATED CELL DIVISION CYCLE 7-RELATED PROTEIN KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;cell communication#GO:0007154 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011406.1|UniProtKB=W5N062 W5N062 PTHR24073:SF315 DRAB5-RELATED RAS-RELATED PROTEIN RAB-29 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000016539.1|UniProtKB=W5NIG6 W5NIG6 PTHR46109:SF3 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG B RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;RNA biosynthetic process#GO:0032774;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007030.1|UniProtKB=W5MJF4 W5MJF4 PTHR21180:SF33 ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1 ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009762.1|UniProtKB=W5MU68 W5MU68 PTHR48129:SF1 60S RIBOSOMAL PROTEIN L37A LARGE RIBOSOMAL SUBUNIT PROTEIN EL43 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000015876.1|UniProtKB=W5NFZ2 W5NFZ2 PTHR24322:SF734 PKSB SI:DKEY-221H15.4 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000002395.1|UniProtKB=W5M352 W5M352 PTHR12626:SF4 PROGRAMMED CELL DEATH 4 PROGRAMMED CELL DEATH PROTEIN 4 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000000679.1|UniProtKB=W5LX94 W5LX94 PTHR48066:SF2 CARNOSINE SYNTHASE 1 CARNOSINE SYNTHASE-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000001576.1|UniProtKB=W5M094 W5M094 PTHR11132:SF427 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E1 antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015568.1|UniProtKB=W5NEV5 W5NEV5 PTHR24346:SF56 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE MARK2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011456.1|UniProtKB=W5N0B6 W5N0B6 PTHR23343:SF117 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 1-LIKE binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198 cell-cell recognition#GO:0009988;binding of sperm to zona pellucida#GO:0007339;sexual reproduction#GO:0019953;cell activation#GO:0001775;cell recognition#GO:0008037;sperm-egg recognition#GO:0035036;biological regulation#GO:0065007;fertilization#GO:0009566;reproductive process#GO:0022414;regulation of reproductive process#GO:2000241;multicellular organismal process#GO:0032501;regulation of biological process#GO:0050789;cellular process#GO:0009987;negative regulation of biological process#GO:0048519;single fertilization#GO:0007338 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 LEPOC|Ensembl=ENSLOCG00000012870.1|UniProtKB=W5N5C9 W5N5C9 PTHR46018:SF2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000011812.1|UniProtKB=W5N1L7 W5N1L7 PTHR28348:SF1 UPF0193 PROTEIN EVG1 UPF0193 PROTEIN EVG1 LEPOC|Ensembl=ENSLOCG00000001071.1|UniProtKB=W5LYJ8 W5LYJ8 PTHR24349:SF468 SERINE/THREONINE-PROTEIN KINASE RIBOSOMAL PROTEIN S6 KINASE, POLYPEPTIDE 4 calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000244.1|UniProtKB=W5LVW1 W5LVW1 PTHR11818:SF103 BETA/GAMMA CRYSTALLIN BETA_GAMMA CRYSTALLIN 'GREEK KEY' DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198 lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005659.1|UniProtKB=W5MEM4 W5MEM4 PTHR23359:SF271 NUCLEOTIDE KINASE ADENYLATE KINASE 8 phosphotransferase activity, phosphate group as acceptor#GO:0016776;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740 ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;organophosphate biosynthetic process#GO:0090407 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153;De novo purine biosynthesis#P02738>Adenylate kinase#P02896 LEPOC|Ensembl=ENSLOCG00000000455.1|UniProtKB=W5LWJ1 W5LWJ1 PTHR11224:SF39 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007025.1|UniProtKB=W5MJF1 W5MJF1 PTHR23293:SF9 FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE BIFUNCTIONAL FAD DIPHOSPHATASE_FAD SYNTHASE adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;flavin-containing compound metabolic process#GO:0042726;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165 transferase#PC00220;metabolite interconversion enzyme#PC00262 Flavin biosynthesis#P02741>FAD synthetase#P02936 LEPOC|Ensembl=ENSLOCG00000011850.1|UniProtKB=W5N1Q7 W5N1Q7 PTHR10903:SF206 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000014426.1|UniProtKB=W5NAV1 W5NAV1 PTHR24006:SF860 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITINYL HYDROLASE 1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012898.1|UniProtKB=W5N5G7 W5N5G7 PTHR17085:SF3 NUCLEAR RECEPTOR COACTIVATOR 4 NUCLEAR RECEPTOR COACTIVATOR 4 response to chemical#GO:0042221;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000007834.1|UniProtKB=W5MMB3 W5MMB3 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000016657.1|UniProtKB=W5NIW7 W5NIW7 PTHR23055:SF79 CALCIUM BINDING PROTEINS HIPPOCALCIN-LIKE PROTEIN 1 metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000005030.1|UniProtKB=W5MCE9 W5MCE9 PTHR12835:SF5 BIOTIN PROTEIN LIGASE BIOTIN--PROTEIN LIGASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a protein#GO:0140096;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000008164.1|UniProtKB=W5MNF6 W5MNF6 PTHR19302:SF33 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 5 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cellular process#GO:0009987;spindle assembly#GO:0051225;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;reproductive process#GO:0022414;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226 microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000009416.1|UniProtKB=W5MSY0 W5MSY0 PTHR43139:SF52 SI:DKEY-122A22.2 MESODERM-SPECIFIC TRANSCRIPT PROTEIN protein modifying enzyme#PC00260;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000011907.1|UniProtKB=W5N1Y1 W5N1Y1 PTHR12297:SF18 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 2A protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000309.1|UniProtKB=W5LW29 W5LW29 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000001678.1|UniProtKB=W5M0M6 W5M0M6 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of immune response#GO:0050776;cell communication#GO:0007154 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009699.1|UniProtKB=W5MTY4 W5MTY4 PTHR45617:SF175 LEUCINE RICH REPEAT FAMILY PROTEIN CARBOXYPEPTIDASE N SUBUNIT 2 PRECURSOR scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016787.1|UniProtKB=W5NJE5 W5NJE5 PTHR11675:SF8 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 14 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004623.1|UniProtKB=W5MAY3 W5MAY3 PTHR10856:SF10 CORONIN CORONIN-1C actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;stem cell development#GO:0048864;actin filament-based process#GO:0030029;tissue development#GO:0009888;neural crest cell development#GO:0014032;cell migration#GO:0016477;cytoskeleton organization#GO:0007010;stem cell differentiation#GO:0048863;organelle organization#GO:0006996;cellular process#GO:0009987;neural crest cell migration#GO:0001755;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;mesenchyme development#GO:0060485;actin filament organization#GO:0007015;mesenchymal cell differentiation#GO:0048762;neural crest cell differentiation#GO:0014033;developmental process#GO:0032502 supramolecular complex#GO:0099080;lamellipodium#GO:0030027;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;actin filament#GO:0005884;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000001132.1|UniProtKB=W5LYU6 W5LYU6 PTHR46841:SF4 OX-2 MEMBRANE GLYCOPROTEIN SC:D189 LEPOC|Ensembl=ENSLOCG00000007800.1|UniProtKB=W5MM56 W5MM56 PTHR10252:SF153 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED CHROMATIN ACCESSIBILITY COMPLEX PROTEIN 1 cellular process#GO:0009987;DNA replication#GO:0006260;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;chromatin remodeling#GO:0006338;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ISWI-type complex#GO:0031010;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016677.1|UniProtKB=W5NIZ5 W5NIZ5 PTHR15223:SF1 NADH-UBIQUINONE OXIDOREDUCTASE AGGG SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2, MITOCHONDRIAL electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007799.1|UniProtKB=W5MM71 W5MM71 PTHR11905:SF112 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 12 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010789.1|UniProtKB=W5MXX0 W5MXX0 PTHR46530:SF1 PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP4 PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP4 glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 FAS signaling pathway#P00020>PARP#P00600 LEPOC|Ensembl=ENSLOCG00000014274.1|UniProtKB=W5NAB6 W5NAB6 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003626.1|UniProtKB=W5M7F3 W5M7F3 PTHR44188:SF3 GDAP1, ISOFORM A GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 1 cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular process#GO:0009987;organelle fusion#GO:0048284;mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 LEPOC|Ensembl=ENSLOCG00000004488.1|UniProtKB=W5MAF5 W5MAF5 PTHR24278:SF38 COAGULATION FACTOR TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 4 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000014144.1|UniProtKB=W5N9W5 W5N9W5 PTHR24377:SF1040 IP01015P-RELATED ZINC FINGER PROTEIN 467 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000016221.1|UniProtKB=W5NH94 W5NH94 PTHR23115:SF188 TRANSLATION FACTOR HBS1-LIKE PROTEIN hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;translation#GO:0006412;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;rescue of stalled cytosolic ribosome#GO:0072344;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;translational elongation#GO:0006414;gene expression#GO:0010467;biosynthetic process#GO:0009058;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000017043.1|UniProtKB=W5NKA3 W5NKA3 PTHR24033:SF234 EGF-LIKE DOMAIN-CONTAINING PROTEIN SUSHI, NIDOGEN AND EGF LIKE DOMAINS 1 neurogenesis#GO:0022008;vasculature development#GO:0001944;system development#GO:0048731;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;cell differentiation#GO:0030154;blood vessel development#GO:0001568;cellular process#GO:0009987 Angiogenesis#P00005>Notch#P00255;Notch signaling pathway#P00045>Notch#P01099;Notch signaling pathway#P00045>NIct#P01119;Alzheimer disease-presenilin pathway#P00004>Notch C-terminal fragment#P00120;Alzheimer disease-presenilin pathway#P00004>Notch transmembrane fragment#P00135;Notch signaling pathway#P00045>Next#P01103;Alzheimer disease-presenilin pathway#P00004>Notch extracellular fragment#P00179;Alzheimer disease-presenilin pathway#P00004>NICD#P00122;Alzheimer disease-presenilin pathway#P00004>Notch N-terminal fragment#P00171;Notch signaling pathway#P00045>NIcs#P01120;Notch signaling pathway#P00045>Ntm#P01114;Alzheimer disease-presenilin pathway#P00004>Notch#P00176;Alzheimer disease-presenilin pathway#P00004>Notch fragment#P00154 LEPOC|Ensembl=ENSLOCG00000011435.1|UniProtKB=W5N094 W5N094 PTHR35255:SF1 TRANSMEMBRANE PROTEIN 71 TRANSMEMBRANE PROTEIN 71 LEPOC|Ensembl=ENSLOCG00000007822.1|UniProtKB=W5MM88 W5MM88 PTHR12736:SF29 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 3 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular response to alcohol#GO:1905957;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to alcohol#GO:1901419;regulation of abscisic acid-activated signaling pathway#GO:0009787;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 LEPOC|Ensembl=ENSLOCG00000012010.1|UniProtKB=W5N2C9 W5N2C9 PTHR45615:SF16 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-9 binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000006931.1|UniProtKB=W5MJ23 W5MJ23 MOCS2 PTHR33359:SF1 MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT metabolic process#GO:0008152;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000011550.1|UniProtKB=W5N0N7 W5N0N7 PTHR24232:SF22 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 4 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Blood coagulation#P00011>PAR-4#P00461 LEPOC|Ensembl=ENSLOCG00000010144.1|UniProtKB=W5MVK8 W5MVK8 PTHR45882:SF1 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>PITX#P06722 LEPOC|Ensembl=ENSLOCG00000017390.1|UniProtKB=W5NLI6 W5NLI6 PTHR24232:SF90 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 5B transmembrane signaling receptor activity#GO:0004888;bioactive lipid receptor activity#GO:0045125;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002370.1|UniProtKB=W5M328 W5M328 PTHR11267:SF104 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000012500.1|UniProtKB=W5N424 W5N424 PTHR12669:SF5 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 3 translation regulator activity#GO:0045182;protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000012464.1|UniProtKB=W5N3Z3 W5N3Z3 PTHR12625:SF1 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR LIMB REGION 1 PROTEIN HOMOLOG transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000380.1|UniProtKB=W5LWA8 W5LWA8 PTHR45639:SF2 HSC70CB, ISOFORM G-RELATED HEAT SHOCK PROTEIN 105 KDA nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp70 family chaperone#PC00027 LEPOC|Ensembl=ENSLOCG00000005947.1|UniProtKB=W5MFM1 W5MFM1 PTHR11829:SF142 FORKHEAD BOX PROTEIN FORK-HEAD DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000006153.1|UniProtKB=W5MGC3 W5MGC3 PTHR46147:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 SET-BINDING PROTEIN catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;histone H3K4 methyltransferase activity#GO:0042800;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000556.1|UniProtKB=W5LWV7 W5LWV7 PTHR21063:SF4 LFA-3 CD48 ANTIGEN ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000001166.1|UniProtKB=W5LYV9 W5LYV9 PTHR12326:SF3 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN DIFFERENTIALLY EXPRESSED IN FDCP 8 HOMOLOG LEPOC|Ensembl=ENSLOCG00000010141.1|UniProtKB=W5MVL8 W5MVL8 PTHR42693:SF9 ARYLSULFATASE FAMILY MEMBER STERYL-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008770.1|UniProtKB=W5MQM3 W5MQM3 PTHR12305:SF99 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE TPTE2-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Hypoxia response via HIF activation#P00030>PTEN#P00824;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway#P00059>PTEN#P01480;p53 pathway feedback loops 2#P04398>PTEN#P04658;p53 pathway#P00059>PTEN#G01579;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;p53 pathway feedback loops 2#P04398>PTEN#G04714 LEPOC|Ensembl=ENSLOCG00000002412.1|UniProtKB=W5M3D2 W5M3D2 PTHR11453:SF139 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;bicarbonate transmembrane transporter activity#GO:0015106;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;localization#GO:0051179;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007 apical part of cell#GO:0045177;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;apical plasma membrane#GO:0016324;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000006391.1|UniProtKB=W5MH60 W5MH60 PTHR12400:SF51 INOSITOL POLYPHOSPHATE KINASE INOSITOL POLYPHOSPHATE MULTIKINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000017687.1|UniProtKB=W5NMD3 W5NMD3 PTHR40472:SF10 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 5 LEPOC|Ensembl=ENSLOCG00000005611.1|UniProtKB=W5MEG6 W5MEG6 PTHR46507:SF4 AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN SYNOVIAL SARCOMA, X BREAKPOINT 2 INTERACTING PROTEIN B cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;intraciliary transport involved in cilium assembly#GO:0035735;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;cilium assembly#GO:0060271 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;centriolar satellite#GO:0034451;cell projection#GO:0042995;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000002039.1|UniProtKB=W5M1V4 W5M1V4 PTHR24231:SF14 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR SUCCINATE RECEPTOR 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016848.1|UniProtKB=W5NJL8 W5NJL8 PTHR47977:SF104 RAS-RELATED PROTEIN RAB CALCIUM RELEASE-ACTIVATED CHANNEL REGULATOR 2AB-RELATED guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 transport#GO:0006810;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000005713.1|UniProtKB=W5MEU0 W5MEU0 PTHR45808:SF6 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096 intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of transport#GO:0051051;signaling#GO:0023052;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174;VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520 LEPOC|Ensembl=ENSLOCG00000007409.1|UniProtKB=W5MKU3 W5MKU3 PTHR12997:SF10 TYPE I INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE INOSITOL POLYPHOSPHATE-5-PHOSPHATASE A phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007716.1|UniProtKB=W5MLW2 W5MLW2 PTHR13363:SF6 RING FINGER AND SRY DOMAIN-CONTAINING RING FINGER AND SPRY DOMAIN-CONTAINING PROTEIN 1 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000006421.1|UniProtKB=W5MH98 W5MH98 PTHR11955:SF152 FATTY ACID BINDING PROTEIN CELLULAR RETINOIC ACID-BINDING PROTEIN 2 organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;binding#GO:0005488;lipid binding#GO:0008289;fatty acid binding#GO:0005504 carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000000393.1|UniProtKB=W5LWC2 W5LWC2 PTHR19944:SF86 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823;protein-containing complex binding#GO:0044877 positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;regulation of immune response#GO:0050776;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cell adhesion#GO:0045785;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;immune system process#GO:0002376;regulation of lymphocyte activation#GO:0051249;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of leukocyte activation#GO:0002696;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684 vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000015971.1|UniProtKB=W5NGB0 W5NGB0 PTHR13693:SF56 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 3 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 sphingoid biosynthetic process#GO:0046520;ceramide metabolic process#GO:0006672;ceramide biosynthetic process#GO:0046513;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000003599.1|UniProtKB=W5M7A7 W5M7A7 PTHR11685:SF314 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING SI:CH211-212K18.15 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;regulation of trans-synaptic signaling#GO:0099177;macroautophagy#GO:0016236;biological regulation#GO:0065007;cellular process#GO:0009987;autophagy#GO:0006914;mitophagy#GO:0000423;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;autophagy of mitochondrion#GO:0000422;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005216.1|UniProtKB=W5MD27 W5MD27 PTHR21716:SF4 TRANSMEMBRANE PROTEIN TRANSMEMBRANE PROTEIN 245 organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011110.1|UniProtKB=W5MZ41 W5MZ41 PTHR21585:SF0 FULL-LENGTH CDNA CLONE CS0DC025YL05 OF NEUROBLASTOMA ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000017997.1|UniProtKB=W5NN89 W5NN89 PTHR24034:SF137 EGF-LIKE DOMAIN-CONTAINING PROTEIN SI:DKEY-163F14.6 cytokine binding#GO:0019955;growth factor binding#GO:0019838;protein binding#GO:0005515;transforming growth factor beta binding#GO:0050431;binding#GO:0005488 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000008080.1|UniProtKB=W5MN53 W5MN53 PTHR35253:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 152 COILED-COIL DOMAIN-CONTAINING PROTEIN 152 LEPOC|Ensembl=ENSLOCG00000003509.1|UniProtKB=W5M705 W5M705 PTHR10127:SF860 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING TOLLOID-LIKE PROTEIN 1 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 dorsal/ventral pattern formation#GO:0009953;primary metabolic process#GO:0044238;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;pattern specification process#GO:0007389;proteolysis#GO:0006508;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;regionalization#GO:0003002;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;developmental process#GO:0032502;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000016488.1|UniProtKB=W5NIA9 W5NIA9 PTHR10127:SF828 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000011911.1|UniProtKB=W5N210 W5N210 PTHR24023:SF912 COLLAGEN ALPHA COLLAGEN ALPHA-1(XV) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000014348.1|UniProtKB=W5NAL5 W5NAL5 PTHR13906:SF12 PORCUPINE PROTEIN-SERINE O-PALMITOLEOYLTRANSFERASE PORCUPINE binding#GO:0005488;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 signal release#GO:0023061;cell communication#GO:0007154;protein secretion#GO:0009306;localization#GO:0051179;secretion#GO:0046903;secretion by cell#GO:0032940;protein transport#GO:0015031;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein localization to extracellular region#GO:0071692;signaling#GO:0023052;export from cell#GO:0140352;metabolic process#GO:0008152;transport#GO:0006810;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000012917.1|UniProtKB=W5N5L0 W5N5L0 PTHR24085:SF8 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR ALPHA binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor binding#GO:0140297;nuclear receptor binding#GO:0016922;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837 response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;cellular response to endogenous stimulus#GO:0071495;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009442.1|UniProtKB=W5MT13 W5MT13 PTHR24270:SF47 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 12 neuron migration#GO:0001764;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell migration#GO:0016477;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell motility#GO:0048870;cell development#GO:0048468;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transfer/carrier protein#PC00219;apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000015785.1|UniProtKB=W5NFM4 W5NFM4 PTHR15592:SF13 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L-LIKE RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000003806.1|UniProtKB=W5M831 W5M831 PTHR12297:SF23 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A, MITOCHONDRIAL cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004016.1|UniProtKB=W5M8U4 W5M8U4 PTHR10807:SF34 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR6 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid modification#GO:0030258;dephosphorylation#GO:0016311 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane#GO:0016020;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000017235.1|UniProtKB=W5NL08 W5NL08 PTHR24300:SF302 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015350.1|UniProtKB=W5NE30 W5NE30 PTHR22603:SF91 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000007988.1|UniProtKB=W5MMU3 W5MMU3 PTHR15136:SF9 STROMAL INTERACTION MOLECULE HOMOLOG STROMAL INTERACTION MOLECULE 1 cation binding#GO:0043169;channel regulator activity#GO:0016247;metal ion binding#GO:0046872;transporter regulator activity#GO:0141108;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246 intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012154.1|UniProtKB=W5N2T9 W5N2T9 PTHR45752:SF48 LEUCINE-RICH REPEAT-CONTAINING MALIGNANT FIBROUS HISTIOCYTOMA-AMPLIFIED SEQUENCE 1 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;immune system process#GO:0002376;inflammatory response#GO:0006954;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;immune response#GO:0006955;signal transduction#GO:0007165;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological regulation#GO:0065007;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003638.1|UniProtKB=W5M7H5 W5M7H5 PTHR24351:SF58 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-3 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 TORC1 signaling#GO:0038202;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;TOR signaling#GO:0031929;biological regulation#GO:0065007;signaling#GO:0023052 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;CCKR signaling map#P06959>RSK1/2#P07153;Interleukin signaling pathway#P00036>p90RSK#P00964;Ras Pathway#P04393>p90RSK#P04541;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 LEPOC|Ensembl=ENSLOCG00000009490.1|UniProtKB=W5MT90 W5MT90 PTHR12199:SF4 INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN 2 carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;glycosaminoglycan binding#GO:0005539;ion binding#GO:0043167;organic acid binding#GO:0043177;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000007035.1|UniProtKB=W5MJG8 W5MJG8 PTHR24057:SF8 GLYCOGEN SYNTHASE KINASE-3 ALPHA GLYCOGEN SYNTHASE KINASE-3 BETA protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;beta-catenin binding#GO:0008013;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;insulin receptor signaling pathway#GO:0008286;negative regulation of cell communication#GO:0010648;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of Wnt signaling pathway#GO:0030111;negative regulation of cellular process#GO:0048523;positive regulation of neuron apoptotic process#GO:0043525;regulation of cell projection organization#GO:0031344;regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869;positive regulation of catabolic process#GO:0009896;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of microtubule-based process#GO:0032886;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;regulation of protein metabolic process#GO:0051246;response to hormone#GO:0009725;regulation of neuron apoptotic process#GO:0043523;positive regulation of autophagy#GO:0010508;regulation of TOR signaling#GO:0032006;response to chemical#GO:0042221;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of intracellular signal transduction#GO:1902531;negative regulation of canonical Wnt signaling pathway#GO:0090090;positive regulation of protein metabolic process#GO:0051247;response to oxygen-containing compound#GO:1901700;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;response to endogenous stimulus#GO:0009719;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of programmed cell death#GO:0043067;positive regulation of programmed cell death#GO:0043068;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;developmental process#GO:0032502;cellular developmental process#GO:0048869;negative regulation of Wnt signaling pathway#GO:0030178;cellular response to nitrogen compound#GO:1901699;regulation of signal transduction#GO:0009966;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cell communication#GO:0007154;regulation of protein catabolic process#GO:0042176;response to nitrogen compound#GO:1901698;positive regulation of protein catabolic process#GO:0045732;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;negative regulation of TOR signaling#GO:0032007;regulation of cytoskeleton organization#GO:0051493;cellular response to peptide hormone stimulus#GO:0071375 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;dendrite#GO:0030425;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;dendritic tree#GO:0097447;axon#GO:0030424;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cell junction#GO:0030054;intracellular protein-containing complex#GO:0140535;glutamatergic synapse#GO:0098978;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cytosol#GO:0005829;nucleus#GO:0005634;neuron projection#GO:0043005 non-receptor serine/threonine protein kinase#PC00167 Cadherin signaling pathway#P00012>GSK3beta#P00477;Hedgehog signaling pathway#P00025>GSK3#P00692;Interleukin signaling pathway#P00036>GSK3#P00976;Ras Pathway#P04393>GSK3#P04546;CCKR signaling map#P06959>GSK3beta#P07199;Gonadotropin-releasing hormone receptor pathway#P06664>GSK3#P06827;Angiogenesis#P00005>GSK3beta#P00211;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GSK#P00714;Wnt signaling pathway#P00057>Glycogen Synthase Kinase-3Beta#P01441;Alzheimer disease-presenilin pathway#P00004>GSK-3beta#P00175;PI3 kinase pathway#P00048>GSK3#P01181;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;PDGF signaling pathway#P00047>GSK3#P01153 LEPOC|Ensembl=ENSLOCG00000002253.1|UniProtKB=W5M2L8 W5M2L8 PTHR12650:SF15 40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI RIBOSOMAL PROTEIN S30, ISOFORM A ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000016156.1|UniProtKB=W5NH00 W5NH00 PTHR14002:SF71 ENDOGLIN/TGF-BETA RECEPTOR TYPE III PANCREATIC SECRETORY GRANULE MEMBRANE MAJOR GLYCOPROTEIN GP2 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001922.1|UniProtKB=W5M1G4 W5M1G4 PTHR45134:SF5 OS08G0543275 PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000006580.1|UniProtKB=W5MHU7 W5MHU7 PTHR10033:SF15 CALSEQUESTRIN CALSEQUESTRIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;molecular sequestering activity#GO:0140313 regulation of heart contraction#GO:0008016;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;regulation of muscle system process#GO:0090257;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of muscle contraction#GO:0006937;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of monoatomic ion transport#GO:0043269;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;signal transduction#GO:0007165;regulation of release of sequestered calcium ion into cytosol#GO:0051279;calcium-mediated signaling#GO:0019722;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of system process#GO:0044057;regulation of monoatomic cation transmembrane transport#GO:1904062 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;supramolecular complex#GO:0099080;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;sarcoplasmic reticulum#GO:0016529;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;membraneless organelle#GO:0043228;sarcomere#GO:0030017;endoplasmic reticulum#GO:0005783;I band#GO:0031674 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000013056.1|UniProtKB=W5N620 W5N620 PTHR13416:SF2 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 43 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000011464.1|UniProtKB=W5N0C4 W5N0C4 PTHR44942:SF6 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN NOVEL PROTEIN LEPOC|Ensembl=ENSLOCG00000001759.1|UniProtKB=W5M0X9 W5M0X9 PTHR17616:SF6 YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER WW DOMAIN-CONTAINING TRANSCRIPTION REGULATOR PROTEIN 1 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;hippo signaling#GO:0035329;positive regulation of macromolecule metabolic process#GO:0010604;regulation of signaling#GO:0023051;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000010867.1|UniProtKB=W5MY80 W5MY80 PTHR24416:SF564 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE-STIMULATING PROTEIN RECEPTOR transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;localization#GO:0051179;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell migration#GO:0016477;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;phagocytosis#GO:0006909;multicellular organism development#GO:0007275;establishment of localization#GO:0051234;import into cell#GO:0098657 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004534.1|UniProtKB=W5MAW8 W5MAW8 PTHR21725:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR4 E3 UBIQUITIN-PROTEIN LIGASE UBR4 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008862.1|UniProtKB=W5MQX8 W5MQX8 PTHR14191:SF6 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF3-RELATED protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular process#GO:0009987;protein localization to plasma membrane#GO:0072659;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009499.1|UniProtKB=W5MT98 W5MT98 PTHR46485:SF3 LIM DOMAIN KINASE 1 DUAL SPECIFICITY TESTIS-SPECIFIC PROTEIN KINASE 1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 organelle organization#GO:0006996;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;positive regulation of actin filament bundle assembly#GO:0032233;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;actin filament-based process#GO:0030029;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000015144.1|UniProtKB=W5NDC9 W5NDC9 PTHR13516:SF5 RIBONUCLEASE P SUBUNIT P25 RIBONUCLEASE P PROTEIN SUBUNIT P25 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172 RNA metabolism protein#PC00031;endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000006921.1|UniProtKB=W5MJ07 W5MJ07 PTHR38706:SF3 SI:CH211-198C19.1-RELATED SI:CH211-198C19.1 LEPOC|Ensembl=ENSLOCG00000015128.1|UniProtKB=W5NDA7 W5NDA7 PTHR42681:SF8 MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015070.1|UniProtKB=W5ND42 W5ND42 PTHR11547:SF24 ARGININE OR CREATINE KINASE CREATINE KINASE U-TYPE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;modified amino acid metabolic process#GO:0006575;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;amino acid kinase#PC00045 LEPOC|Ensembl=ENSLOCG00000009667.1|UniProtKB=W5MTV0 W5MTV0 PTHR23055:SF82 CALCIUM BINDING PROTEINS A-TYPE POTASSIUM CHANNEL MODULATORY PROTEIN KCNIP1 protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;channel regulator activity#GO:0016247;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;potassium channel regulator activity#GO:0015459;calcium ion binding#GO:0005509;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106 regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of localization#GO:0032879;regulation of transport#GO:0051049 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000010670.1|UniProtKB=W5MXF9 W5MXF9 PTHR12062:SF11 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN MGAT4E acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000013628.1|UniProtKB=W5N843 W5N843 PTHR15025:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762 monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;sarcolemma#GO:0042383;transporter complex#GO:1990351;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009173.1|UniProtKB=W5MS29 W5MS29 PTHR28630:SF34 FAMILY NOT NAMED PEROXIREDOXIN-LIKE 2C LEPOC|Ensembl=ENSLOCG00000005120.1|UniProtKB=W5MCS1 W5MCS1 PTHR23411:SF36 TAPASIN IMMUNOGLOBULIN KAPPA CONSTANT immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012680.1|UniProtKB=W5N4P4 W5N4P4 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000411.1|UniProtKB=W5LWE2 W5LWE2 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000008783.1|UniProtKB=W5MQN4 W5MQN4 MED10 PTHR13345:SF13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013704.1|UniProtKB=W5N8E3 W5N8E3 PTHR14374:SF0 FOIE GRAS TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11 LEPOC|Ensembl=ENSLOCG00000016077.1|UniProtKB=W5NGQ2 W5NGQ2 PTHR23358:SF4 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET3 dioxygenase activity#GO:0051213;catalytic activity, acting on DNA#GO:0140097;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008267.1|UniProtKB=W5MNS7 W5MNS7 PTHR23193:SF23 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP153 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198;molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;intracellular protein transport#GO:0006886;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012641.1|UniProtKB=W5N4J7 W5N4J7 PTHR11256:SF41 BCL-2 RELATED BCL-2 HOMOLOGOUS ANTAGONIST_KILLER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;organelle organization#GO:0006996;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of cellular process#GO:0048522;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 Apoptosis signaling pathway#P00006>Bak#P00275 LEPOC|Ensembl=ENSLOCG00000007659.1|UniProtKB=W5MLN7 W5MLN7 PTHR11216:SF64 EH DOMAIN RALBP1-ASSOCIATED EPS DOMAIN-CONTAINING PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;import into cell#GO:0098657;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008543.1|UniProtKB=W5MPT8 W5MPT8 PTHR10730:SF28 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN GALACTOSYLTRANSFERASE 1 galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005001.1|UniProtKB=W5MCB3 W5MCB3 PTHR15417:SF4 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1A enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;phosphatase inhibitor#PC00183;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000003367.1|UniProtKB=W5M6H4 W5M6H4 PTHR22909:SF24 GOLGI INTEGRAL MEMBRANE PROTEIN 4 GOLGI INTEGRAL MEMBRANE PROTEIN 4A ISOFORM X1-RELATED cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000012339.1|UniProtKB=W5N3I5 W5N3I5 PTHR18934:SF95 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX15 isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007147.1|UniProtKB=W5MJU3 W5MJU3 PTHR43391:SF8 RETINOL DEHYDROGENASE-RELATED RETINOL DEHYDROGENASE 8 all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000016654.1|UniProtKB=W5NIW5 W5NIW5 PTHR10877:SF185 POLYCYSTIN FAMILY MEMBER POLYCYSTIN FAMILY RECEPTOR FOR EGG JELLY monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to mechanical stimulus#GO:0009612;detection of mechanical stimulus#GO:0050982;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000012731.1|UniProtKB=W5N4V7 W5N4V7 PTHR15143:SF0 TELETHONIN TELETHONIN protein binding#GO:0005515;structural molecule activity#GO:0005198;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;response to mechanical stimulus#GO:0009612;anatomical structure development#GO:0048856;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;neuromuscular process#GO:0050905;muscle structure development#GO:0061061;animal organ morphogenesis#GO:0009887;striated muscle contraction#GO:0006941;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;protein-containing complex organization#GO:0043933;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;muscle organ development#GO:0007517;striated muscle tissue development#GO:0014706;cardiac muscle cell differentiation#GO:0055007;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;nervous system process#GO:0050877;response to stimulus#GO:0050896;cell development#GO:0048468;response to abiotic stimulus#GO:0009628;anatomical structure morphogenesis#GO:0009653;protein-containing complex assembly#GO:0065003;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;system process#GO:0003008;heart contraction#GO:0060047;response to external stimulus#GO:0009605;detection of mechanical stimulus#GO:0050982;developmental process#GO:0032502;muscle contraction#GO:0006936;tissue development#GO:0009888;blood circulation#GO:0008015;detection of stimulus#GO:0051606;tissue morphogenesis#GO:0048729;system development#GO:0048731;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;circulatory system process#GO:0003013;organelle assembly#GO:0070925;cardiac muscle contraction#GO:0060048;actin cytoskeleton organization#GO:0030036;heart morphogenesis#GO:0003007;myofibril assembly#GO:0030239;animal organ development#GO:0048513;heart development#GO:0007507;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;circulatory system development#GO:0072359;cell differentiation#GO:0030154;skeletal muscle contraction#GO:0003009;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;heart process#GO:0003015;muscle system process#GO:0003012 myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;I band#GO:0031674;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;Z disc#GO:0030018;contractile muscle fiber#GO:0043292 LEPOC|Ensembl=ENSLOCG00000015897.1|UniProtKB=W5NG18 W5NG18 PTHR22912:SF151 DISULFIDE OXIDOREDUCTASE DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000000366.1|UniProtKB=W5LW93 W5LW93 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007582.1|UniProtKB=W5MLD9 W5MLD9 PTHR11537:SF61 VOLTAGE-GATED POTASSIUM CHANNEL DELAYED-RECTIFIER POTASSIUM CHANNEL REGULATORY SUBUNIT KCNS1 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108 action potential#GO:0001508;metal ion transport#GO:0030001;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000017684.1|UniProtKB=W5NMD0 W5NMD0 PTHR40472:SF9 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN RAPUNZEL 4 LEPOC|Ensembl=ENSLOCG00000009077.1|UniProtKB=W5MRQ0 W5MRQ0 PTHR46105:SF1 AGAP004733-PA TRANSCRIPTION REGULATOR PROTEIN BACH1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002770.1|UniProtKB=W5M4F3 W5M4F3 PTHR48614:SF1 AT03386P MAPK REGULATED COREPRESSOR INTERACTING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000005050.1|UniProtKB=W5MCG9 W5MCG9 PTHR20914:SF24 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 LYMPHOCYTE ANTIGEN 6 FAMILY MEMBER M2-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001970.1|UniProtKB=W5M1N5 W5M1N5 PTHR11616:SF44 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT TRANSPORTER XTRP3 neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324 import into cell#GO:0098657;establishment of localization#GO:0051234;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;glycine transport#GO:0015816;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;L-alpha-amino acid transmembrane transport#GO:1902475 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 LEPOC|Ensembl=ENSLOCG00000008728.1|UniProtKB=W5MQG0 W5MQG0 PTHR22802:SF475 C-TYPE LECTIN SUPERFAMILY MEMBER CD302 ANTIGEN signaling receptor activity#GO:0038023;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008884.1|UniProtKB=W5MR04 W5MR04 PTHR12802:SF189 SWI/SNF COMPLEX-RELATED DEUBIQUITINASE MYSM1 protein binding#GO:0005515;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;histone binding#GO:0042393;binding#GO:0005488;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003709.1|UniProtKB=W5M7Q9 W5M7Q9 PTHR28608:SF1 INTEGRATOR COMPLEX SUBUNIT 2 INTEGRATOR COMPLEX SUBUNIT 2 transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound catabolic process#GO:0034655;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;DNA-templated transcription initiation#GO:0006352 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;integrator complex#GO:0032039;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000016327.1|UniProtKB=W5NHP7 W5NHP7 PTHR12496:SF9 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25-RELATED RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000008983.1|UniProtKB=W5MRE2 W5MRE2 PTHR45889:SF7 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 2B ISOFORM X1 cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609 LEPOC|Ensembl=ENSLOCG00000013426.1|UniProtKB=W5N7E8 W5N7E8 MTAP PTHR42679:SF2 S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 Purine metabolism#P02769>Nucleoside Phosphorylase#P03115 LEPOC|Ensembl=ENSLOCG00000016793.1|UniProtKB=W5NJE7 W5NJE7 PTHR12121:SF27 CARBON CATABOLITE REPRESSOR PROTEIN 4 RNA 2',3'-CYCLIC PHOSPHATASE ANGEL2 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;hydrolase activity#GO:0016787;mRNA 3'-UTR binding#GO:0003730;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;phosphoric ester hydrolase activity#GO:0042578;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;mRNA binding#GO:0003729;binding#GO:0005488;nuclease activity#GO:0004518 biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;mitochondrial RNA 3'-end processing#GO:0000965;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;mRNA processing#GO:0006397;regulation of mRNA metabolic process#GO:1903311;RNA 3'-end processing#GO:0031123;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial RNA processing#GO:0000963;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;nucleic acid biosynthetic process#GO:0141187 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000008948.1|UniProtKB=W5MRA3 W5MRA3 PTHR45739:SF15 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 3 PRECURSOR epithelial structure maintenance#GO:0010669;homeostatic process#GO:0042592;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;cellular process#GO:0009987;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000001408.1|UniProtKB=W5LZR6 W5LZR6 PTHR11566:SF225 DYNAMIN INTERFERON-INDUCED GTP-BINDING PROTEIN MX-RELATED pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;tubulin binding#GO:0015631;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787 defense response#GO:0006952;vesicle budding from membrane#GO:0006900;response to external stimulus#GO:0009605;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;response to other organism#GO:0051707;membrane organization#GO:0061024;synaptic vesicle recycling#GO:0036465;vesicle localization#GO:0051648;response to virus#GO:0009615;localization#GO:0051179;organelle localization#GO:0051640;response to external biotic stimulus#GO:0043207;synaptic vesicle endocytosis#GO:0048488;vesicle organization#GO:0016050;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;response to stress#GO:0006950;synaptic vesicle transport#GO:0048489;response to biotic stimulus#GO:0009607;organelle organization#GO:0006996;cellular localization#GO:0051641;biological process involved in interspecies interaction between organisms#GO:0044419;establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;response to stimulus#GO:0050896;cellular component organization#GO:0016043;defense response to virus#GO:0051607 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001990.1|UniProtKB=W5M1P2 W5M1P2 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000009492.1|UniProtKB=W5MT85 W5MT85 PTHR46608:SF3 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;anion binding#GO:0043168 establishment of localization#GO:0051234;import into cell#GO:0098657;endocytosis#GO:0006897;apoptotic cell clearance#GO:0043277;localization#GO:0051179;transport#GO:0006810;phagocytosis#GO:0006909 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015101.1|UniProtKB=W5ND82 W5ND82 PTHR10110:SF94 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 6 metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;recycling endosome#GO:0055037 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000007632.1|UniProtKB=W5MLJ7 W5MLJ7 PTHR46460:SF1 METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004536.1|UniProtKB=W5MAL4 W5MAL4 PTHR10709:SF10 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1B Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cortical actin cytoskeleton organization#GO:0030866 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912;Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876 LEPOC|Ensembl=ENSLOCG00000006677.1|UniProtKB=W5MI74 W5MI74 PTHR10183:SF402 CALPAIN CALPAIN-5 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000011001.1|UniProtKB=W5MYN4 W5MYN4 PTHR11759:SF1 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;translation#GO:0006412;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000017566.1|UniProtKB=W5NM12 W5NM12 PTHR24225:SF56 CHEMOTACTIC RECEPTOR C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of biological quality#GO:0065008;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006169.1|UniProtKB=W5MGE2 W5MGE2 PTHR10224:SF5 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL GLUTAMINE AMIDOTRANSFERASE LIKE CLASS 1 DOMAIN CONTAINING 3A-LIKE1-RELATED LEPOC|Ensembl=ENSLOCG00000013547.1|UniProtKB=W5N7V2 W5N7V2 PTHR46349:SF2 CINGULIN-LIKE PROTEIN 1-RELATED CINGULIN-LIKE PROTEIN 1 intracellular protein localization#GO:0008104;localization#GO:0051179;macromolecule localization#GO:0033036;protein localization to cell junction#GO:1902414 cellular anatomical structure#GO:0110165;tight junction#GO:0070160;bicellular tight junction#GO:0005923;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;apical junction complex#GO:0043296 LEPOC|Ensembl=ENSLOCG00000009727.1|UniProtKB=W5MU17 W5MU17 PTHR10288:SF229 KH DOMAIN CONTAINING RNA BINDING PROTEIN RNA-BINDING PROTEIN NOVA-1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;animal gross anatomical part developmental process#GO:0160108;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nervous system development#GO:0007399;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;developmental process#GO:0032502;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016944.1|UniProtKB=W5NJY7 W5NJY7 PTHR13675:SF0 LYR MOTIF-CONTAINING PROTEIN 2 LYR MOTIF-CONTAINING PROTEIN 2 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001144.1|UniProtKB=W5LYT7 W5LYT7 PTHR12460:SF3 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 1B enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015542.1|UniProtKB=W5NES2 W5NES2 PTHR20908:SF4 LD15586P TRANSMEMBRANE PROTEIN 53 LEPOC|Ensembl=ENSLOCG00000014493.1|UniProtKB=W5NB29 W5NB29 PTHR20937:SF17 IP14615P MESODERM POSTERIOR PROTEIN 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;epithelium development#GO:0060429;mesoderm formation#GO:0001707;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regionalization#GO:0003002;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;tissue morphogenesis#GO:0048729;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;heart morphogenesis#GO:0003007;mesoderm morphogenesis#GO:0048332;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;anterior/posterior pattern specification#GO:0009952;anatomical structure formation involved in morphogenesis#GO:0048646;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;mesoderm development#GO:0007498;anterior/posterior axis specification#GO:0009948;animal organ development#GO:0048513;embryonic pattern specification#GO:0009880;embryo development#GO:0009790;heart development#GO:0007507;formation of primary germ layer#GO:0001704;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;gastrulation#GO:0007369;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000017396.1|UniProtKB=W5NLJ2 W5NLJ2 PTHR24369:SF240 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-LIKE cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000014694.1|UniProtKB=W5NBS9 W5NBS9 PTHR11240:SF85 RIBONUCLEASE T2 RIBONUCLEASE T2-LIKE PRECURSOR catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000004574.1|UniProtKB=W5MAR7 W5MAR7 PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 CILIARY MICROTUBULE INNER PROTEIN 2B LEPOC|Ensembl=ENSLOCG00000004919.1|UniProtKB=W5MC06 W5MC06 PTHR13455:SF3 TRANSCRIPTIONAL REPRESSOR P66-RELATED TRANSCRIPTIONAL REPRESSOR P66-ALPHA DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000005688.1|UniProtKB=W5MER1 W5MER1 PTHR23106:SF24 ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1 ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1 multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;tube development#GO:0035295;blood vessel morphogenesis#GO:0048514;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008458.1|UniProtKB=W5MPI7 W5MPI7 PTHR11042:SF160 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005945.1|UniProtKB=W5MFQ8 W5MFQ8 PTHR10554:SF2 SYNTROPHIN GAMMA-1-SYNTROPHIN plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002581.1|UniProtKB=W5M3S2 W5M3S2 PTHR24067:SF258 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G1 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000013408.1|UniProtKB=W5N7D1 W5N7D1 PTHR43157:SF27 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED NADP-RETINOL DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000016063.1|UniProtKB=W5NGN6 W5NGN6 PTHR23382:SF34 MALATE DEHYDROGENASE MALATE DEHYDROGENASE, CYTOPLASMIC oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing compound metabolic process#GO:0006139;pyridine-containing compound metabolic process#GO:0072524;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 TCA cycle#P00051>Malate Dehydrogenase#P01270 LEPOC|Ensembl=ENSLOCG00000012518.1|UniProtKB=W5N457 W5N457 PTHR45956:SF9 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN AND FYVE DOMAIN-CONTAINING 1 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;regulation of localization#GO:0032879;regulation of transport#GO:0051049;transport#GO:0006810;regulation of endocytosis#GO:0030100 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009614.1|UniProtKB=W5MTN2 W5MTN2 PTHR45893:SF3 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 3 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000013077.1|UniProtKB=W5N648 W5N648 PTHR24412:SF510 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 12 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010301.1|UniProtKB=W5MW59 W5MW59 PTHR14167:SF62 SH3 DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE SH3RF3 molecular adaptor activity#GO:0060090;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;protein-macromolecule adaptor activity#GO:0030674;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006525.1|UniProtKB=W5MHM7 W5MHM7 PTHR24168:SF24 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 4 negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;negative regulation of protein polymerization#GO:0032272;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of cellular component organization#GO:0051129;regulation of protein-containing complex assembly#GO:0043254;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000011836.1|UniProtKB=W5N1P5 W5N1P5 PTHR46092:SF3 HOMEOBOX PROTEIN HOX-A11-RELATED HOMEOBOX PROTEIN HOX-A11 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;skeletal system morphogenesis#GO:0048705 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000018235.1|UniProtKB=W5NNX7 W5NNX7 PTHR24392:SF39 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 518A DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000010212.1|UniProtKB=W5MVU2 W5MVU2 PTHR46593:SF1 TRANSMEMBRANE PROTEIN 64 TRANSMEMBRANE PROTEIN 64 calcium ion homeostasis#GO:0055074;regulation of myeloid cell differentiation#GO:0045637;inorganic ion homeostasis#GO:0098771;regulation of bone resorption#GO:0045124;intracellular monoatomic ion homeostasis#GO:0006873;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;intracellular calcium ion homeostasis#GO:0006874;chemical homeostasis#GO:0048878;positive regulation of cell differentiation#GO:0045597;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;monoatomic ion homeostasis#GO:0050801;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;regulation of hemopoiesis#GO:1903706;regulation of tissue remodeling#GO:0034103;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;homeostatic process#GO:0042592;regulation of cytosolic calcium ion concentration#GO:0051480;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;regulation of cell differentiation#GO:0045595;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;positive regulation of developmental process#GO:0051094;biological regulation#GO:0065007;regulation of bone remodeling#GO:0046850;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;positive regulation of myeloid cell differentiation#GO:0045639 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000013491.1|UniProtKB=W5N7P3 W5N7P3 PTHR11915:SF248 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, ERYTHROCYTIC binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029 cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000007371.1|UniProtKB=W5MKM8 W5MKM8 PTHR13151:SF2 CBF1 INTERACTING COREPRESSOR CIR COREPRESSOR OF RBPJ AND SPLICING REGULATOR transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 Notch signaling pathway#P00045>CoR#P01112 LEPOC|Ensembl=ENSLOCG00000017935.1|UniProtKB=W5NN29 W5NN29 PTHR24062:SF158 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005285.1|UniProtKB=W5MDA7 W5MDA7 PTHR24229:SF11 NEUROPEPTIDES RECEPTOR NOCICEPTIN RECEPTOR G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;binding#GO:0005488;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;system process#GO:0003008;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;sensory perception of pain#GO:0019233;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000003097.1|UniProtKB=W5M5I7 W5M5I7 PTHR33198:SF26 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005126.1|UniProtKB=W5MCR0 W5MCR0 PTHR31501:SF3 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000010809.1|UniProtKB=W5MXZ4 W5MXZ4 PTHR23282:SF140 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM AND LDL-RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 1 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000009096.1|UniProtKB=W5MRT2 W5MRT2 PTHR11388:SF160 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002162.1|UniProtKB=W5M2A7 W5M2A7 PTHR10666:SF424 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN EL40 FUSION PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987 ribosome#GO:0005840;nucleus#GO:0005634;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000015352.1|UniProtKB=W5NE33 W5NE33 PTHR19877:SF13 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000005253.1|UniProtKB=W5MD73 W5MD73 SHANK2 PTHR24135:SF17 SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 2 signaling adaptor activity#GO:0035591;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;cellular component organization#GO:0016043;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501;synapse organization#GO:0050808;nervous system process#GO:0050877;cognition#GO:0050890;system process#GO:0003008;cellular component organization or biogenesis#GO:0071840 dendritic tree#GO:0097447;postsynaptic density#GO:0014069;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 Ionotropic glutamate receptor pathway#P00037>PSD95#P00999 LEPOC|Ensembl=ENSLOCG00000013776.1|UniProtKB=W5N8N3 W5N8N3 PTHR12787:SF0 RIBOSOMAL RNA-PROCESSING PROTEIN 8 RIBOSOMAL RNA-PROCESSING PROTEIN 8 catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;nucleolus organization#GO:0007000 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000010103.1|UniProtKB=W5MVG3 W5MVG3 PTHR12683:SF13 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;response to stimulus#GO:0050896;DNA-templated transcription initiation#GO:0006352;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654 transcription factor TFIIH holo complex#GO:0005675;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012455.1|UniProtKB=W5N3Y2 W5N3Y2 PTHR15427:SF57 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER MULTIMERIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004084.1|UniProtKB=W5M920 W5M920 PTHR16052:SF4 TBCC DOMAIN-CONTAINING PROTEIN 1 TBCC DOMAIN-CONTAINING PROTEIN 1 organelle localization#GO:0051640;cellular process#GO:0009987;cellular localization#GO:0051641;localization#GO:0051179;centrosome localization#GO:0051642 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000012414.1|UniProtKB=W5N3S3 W5N3S3 PTHR21236:SF5 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF7 vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane fusion#GO:0061025;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;vesicle fusion#GO:0006906;Golgi organization#GO:0007030;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014626.1|UniProtKB=W5NBJ4 W5NBJ4 PTHR11242:SF13 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 9B metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein modification process#GO:0036211;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 membrane#GO:0016020;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017816.1|UniProtKB=W5NMR1 W5NMR1 PTHR23334:SF3 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN DELTA RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cell differentiation#GO:0045595;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000013888.1|UniProtKB=W5N916 W5N916 PTHR11818:SF15 BETA/GAMMA CRYSTALLIN BETAGAMMAX-CRYSTALLIN structural molecule activity#GO:0005198 sensory system development#GO:0048880;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008839.1|UniProtKB=W5MQU8 W5MQU8 PTHR12757:SF3 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8 regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Huntington disease#P00029>FIP-2#P00772 LEPOC|Ensembl=ENSLOCG00000003012.1|UniProtKB=W5M586 W5M586 PTHR10476:SF17 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1A protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;late endosome to vacuole transport#GO:0045324;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003102.1|UniProtKB=W5M5J2 W5M5J2 PTHR48422:SF2 PROTEIN EVA-1 HOMOLOG B-RELATED PROTEIN EVA-1 HOMOLOG B LEPOC|Ensembl=ENSLOCG00000011273.1|UniProtKB=W5MZP4 W5MZP4 PTHR24369:SF204 ANTIGEN BSP, PUTATIVE-RELATED EXTRACELLULAR LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN CONTAINING 2A PRECURSOR-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005531.1|UniProtKB=W5ME64 W5ME64 PTHR24173:SF44 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 13 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008195.1|UniProtKB=W5MNK6 W5MNK6 PTHR15367:SF4 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC7-LIKE RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991 DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000005914.1|UniProtKB=W5MFI5 W5MFI5 PTHR22767:SF5 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 16, NATA AUXILIARY SUBUNIT enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000014490.1|UniProtKB=W5NB22 W5NB22 CTDNEP1 PTHR12210:SF70 DULLARD PROTEIN PHOSPHATASE CTD NUCLEAR ENVELOPE PHOSPHATASE 1 protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000016109.1|UniProtKB=W5NGU1 W5NGU1 PTHR24366:SF182 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 4 LIKE 2 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000009767.1|UniProtKB=W5MU80 W5MU80 PTHR10408:SF6 STEROL O-ACYLTRANSFERASE STEROL O-ACYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;heterocyclic compound binding#GO:1901363;alcohol binding#GO:0043178;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;steroid binding#GO:0005496;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;sterol binding#GO:0032934;acyltransferase activity#GO:0016746;ion binding#GO:0043167;cholesterol binding#GO:0015485;lipid binding#GO:0008289 secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;lipid localization#GO:0010876;steroid metabolic process#GO:0008202;lipid transport#GO:0006869;cholesterol efflux#GO:0033344;cellular process#GO:0009987;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;sterol metabolic process#GO:0016125;sterol transport#GO:0015918;establishment of localization#GO:0051234;cholesterol metabolic process#GO:0008203;transport#GO:0006810;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 LEPOC|Ensembl=ENSLOCG00000004610.1|UniProtKB=W5MAW5 W5MAW5 PTHR11242:SF2 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED ARYL-HYDROCARBON-INTERACTING PROTEIN-LIKE 1 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011693.1|UniProtKB=W5N160 W5N160 PTHR14336:SF15 TANDEM PH DOMAIN CONTAINING PROTEIN DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE anion binding#GO:0043168;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003560.1|UniProtKB=W5M764 W5M764 PTHR45920:SF3 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FH1_FH2 DOMAIN-CONTAINING PROTEIN 3 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cardiac muscle cell differentiation#GO:0055007;heart development#GO:0007507;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;circulatory system development#GO:0072359;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;positive regulation of organelle organization#GO:0010638;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;positive regulation of actin filament bundle assembly#GO:0032233;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;regulation of supramolecular fiber organization#GO:1902903;muscle cell development#GO:0055001;regulation of stress fiber assembly#GO:0051492;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;muscle tissue development#GO:0060537;system development#GO:0048731;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010810.1|UniProtKB=W5MXY8 W5MXY8 PTHR10605:SF55 HEPARAN SULFATE SULFOTRANSFERASE SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000012785.1|UniProtKB=W5N523 W5N523 PTHR10185:SF27 PHOSPHOLIPASE D - RELATED 5'-3' EXONUCLEASE PLD4 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000015035.1|UniProtKB=W5ND01 W5ND01 PTHR12997:SF9 TYPE I INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE INOSITOL-POLYPHOSPHATE 5-PHOSPHATASE catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005469.1|UniProtKB=W5MDY5 W5MDY5 PTHR10442:SF0 40S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN ES21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;rRNA processing#GO:0006364;protein metabolic process#GO:0019538;translation#GO:0006412;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000018004.1|UniProtKB=W5NN96 W5NN96 PTHR11537:SF171 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNF1 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000011489.1|UniProtKB=W5N0G6 W5N0G6 PTHR13710:SF152 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q5 macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;response to stimulus#GO:0050896 chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003597.1|UniProtKB=W5M7E6 W5M7E6 PTHR11412:SF160 MACROGLOBULIN / COMPLEMENT ALPHA-2-MACROGLOBULIN-LIKE PROTEIN 1 ISOFORM X1 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000018173.1|UniProtKB=W5NNR5 W5NNR5 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003796.1|UniProtKB=W5M821 W5M821 PTHR14491:SF3 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHB LEPOC|Ensembl=ENSLOCG00000002388.1|UniProtKB=W5M336 W5M336 PTHR26451:SF860 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013892.1|UniProtKB=W5N921 W5N921 PTHR13703:SF70 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;molecular function regulator activity#GO:0098772;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to growth factor stimulus#GO:0071363;signal transduction#GO:0007165;cellular process#GO:0009987;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000011215.1|UniProtKB=W5MZH9 W5MZH9 PTHR18864:SF1 KINECTIN KINECTIN LEPOC|Ensembl=ENSLOCG00000000139.1|UniProtKB=W5LVJ5 W5LVJ5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000005366.1|UniProtKB=W5MDL4 W5MDL4 PTHR12560:SF8 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 5 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007876.1|UniProtKB=W5MMG6 W5MMG6 PTHR15350:SF10 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 CONSTITUTIVE PHOTOMORPHOGENIC HOMOLOG SUBUNIT 7A macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987 COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000012219.1|UniProtKB=W5N326 W5N326 PTHR43880:SF21 ALCOHOL DEHYDROGENASE S-(HYDROXYMETHYL)GLUTATHIONE DEHYDROGENASE cation binding#GO:0043169;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;small molecule binding#GO:0036094;binding#GO:0005488;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;zinc ion binding#GO:0008270;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 small molecule catabolic process#GO:0044282;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;response to toxic substance#GO:0009636;cellular response to stimulus#GO:0051716;cellular detoxification of aldehyde#GO:0110095;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000000705.1|UniProtKB=W5LXC6 W5LXC6 PTHR22747:SF13 NUCLEOPLASMIN NUCLEOPLASMIN-3 binding#GO:0005488;nucleic acid binding#GO:0003676;histone binding#GO:0042393;chromatin binding#GO:0003682;protein binding#GO:0005515;RNA binding#GO:0003723 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004639.1|UniProtKB=W5MB03 W5MB03 PTHR18934:SF136 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX35-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007534.1|UniProtKB=W5ML79 W5ML79 PTHR24180:SF58 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 49 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 kinase inhibitor#PC00139;kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000016346.1|UniProtKB=W5NHS6 W5NHS6 PTHR10334:SF577 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN 3 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000009504.1|UniProtKB=W5MTB8 W5MTB8 PTHR43066:SF1 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 4 serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000013432.1|UniProtKB=W5N7F2 W5N7F2 PTHR45946:SF5 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-B1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013837.1|UniProtKB=W5N8W3 W5N8W3 PTHR24035:SF127 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 11 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 membrane organization#GO:0061024;cellular process#GO:0009987;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;phagocytosis#GO:0006909;transport#GO:0006810;membrane invagination#GO:0010324;substrate adhesion-dependent cell spreading#GO:0034446;endocytosis#GO:0006897;cellular component organization#GO:0016043;localization#GO:0051179;cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000005958.1|UniProtKB=W5MFN4 W5MFN4 PTHR12413:SF2 DOLICHYL GLYCOSYLTRANSFERASE DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000003099.1|UniProtKB=W5M5J9 W5M5J9 PTHR10997:SF8 IMPORTIN-7, 8, 11 EXPORTIN-2 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;protein import into nucleus#GO:0006606;nuclear export#GO:0051168;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;cytosol#GO:0005829 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007328.1|UniProtKB=W5MKG6 W5MKG6 PTHR10845:SF32 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 13 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 LEPOC|Ensembl=ENSLOCG00000011868.1|UniProtKB=W5N1T2 W5N1T2 PTHR46260:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 8A LEPOC|Ensembl=ENSLOCG00000010489.1|UniProtKB=W5MWU5 W5MWU5 PTHR12558:SF50 CELL DIVISION CYCLE 16,23,27 SI:DKEY-12J5.1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 cellular process#GO:0009987;cell division#GO:0051301 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012799.1|UniProtKB=W5N539 W5N539 PTHR24243:SF207 G-PROTEIN COUPLED RECEPTOR NEUROTENSIN RECEPTOR TYPE 1-LIKE transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013917.1|UniProtKB=W5N945 W5N945 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE LEPOC|Ensembl=ENSLOCG00000003696.1|UniProtKB=W5M7N8 W5M7N8 PTHR30336:SF20 INNER MEMBRANE PROTEIN, PROBABLE PERMEASE DUF218 DOMAIN-CONTAINING PROTEIN transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001793.1|UniProtKB=W5M141 W5M141 PTHR18884:SF64 SEPTIN SEPTIN-2 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 macromolecule localization#GO:0033036;cell cycle#GO:0007049;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012844.1|UniProtKB=W5N5A2 W5N5A2 PTHR10996:SF230 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009585.1|UniProtKB=W5MTK0 W5MTK0 PTHR10634:SF26 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000000504.1|UniProtKB=W5LWQ2 W5LWQ2 PTHR22891:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-3 RNA binding#GO:0003723;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA nuclease activity#GO:0004540;single-stranded RNA binding#GO:0003727;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000017418.1|UniProtKB=W5NLL4 W5NLL4 PTHR24247:SF34 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1F G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 LEPOC|Ensembl=ENSLOCG00000014243.1|UniProtKB=W5NA81 W5NA81 PTHR23113:SF157 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 4 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of lymphocyte mediated immunity#GO:0002706;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;intracellular signaling cassette#GO:0141124;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of response to biotic stimulus#GO:0002831;cellular response to stimulus#GO:0051716;regulation of natural killer cell mediated immunity#GO:0002715;regulation of leukocyte mediated immunity#GO:0002703;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;positive regulation of innate immune response#GO:0045089 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 LEPOC|Ensembl=ENSLOCG00000002082.1|UniProtKB=W5M252 W5M252 PTHR21567:SF28 CLASP CLIP-ASSOCIATING PROTEIN 1 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 establishment of spindle localization#GO:0051293;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051;establishment of localization#GO:0051234;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;organelle assembly#GO:0070925;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;mitotic spindle organization#GO:0007052;establishment of organelle localization#GO:0051656;nuclear division#GO:0000280;spindle localization#GO:0051653;cellular localization#GO:0051641 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;spindle#GO:0005819;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;mitotic spindle#GO:0072686;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;kinetochore#GO:0000776;basal part of cell#GO:0045178;chromosome#GO:0005694;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000003754.1|UniProtKB=W5M7W6 W5M7W6 PTHR11524:SF12 60S RIBOSOMAL PROTEIN L7 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000006597.1|UniProtKB=W5MHX5 W5MHX5 PTHR12083:SF9 BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE nucleobase-containing compound kinase activity#GO:0019205;hydrolase activity#GO:0016787;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 nucleotide phosphatase#PC00173;phosphatase#PC00181;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012463.1|UniProtKB=W5N3Y5 W5N3Y5 PTHR22012:SF2 FIBROUS SHEATH INTERACTING PROTEIN 1 FIBROUS SHEATH-INTERACTING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006457.1|UniProtKB=W5MHD8 W5MHD8 PTHR33865:SF3 PROTEIN FAM183B CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 144 ciliary base#GO:0097546;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000006054.1|UniProtKB=W5MG00 W5MG00 PTHR12011:SF454 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G2 ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013438.1|UniProtKB=W5N7G6 W5N7G6 PTHR48041:SF92 ABC TRANSPORTER G FAMILY MEMBER 28 BROAD SUBSTRATE SPECIFICITY ATP-BINDING CASSETTE TRANSPORTER ABCG2 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;efflux transmembrane transporter activity#GO:0015562;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 export from cell#GO:0140352;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;localization#GO:0051179;circulatory system process#GO:0003013;detoxification#GO:0098754;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;cellular process#GO:0009987;detoxification of inorganic compound#GO:0061687;system process#GO:0003008;establishment of localization#GO:0051234;transport#GO:0006810;xenobiotic transport#GO:0042908 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017909.1|UniProtKB=W5NN03 W5NN03 PTHR11537:SF24 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 1 gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 action potential#GO:0001508;metal ion transport#GO:0030001;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;potassium ion transport#GO:0006813;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell body#GO:0044297;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;main axon#GO:0044304;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell junction#GO:0030054 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000002241.1|UniProtKB=W5M2J9 W5M2J9 PTHR12753:SF1 AD-003 - RELATED N-TERMINAL XAA-PRO-LYS N-METHYLTRANSFERASE 1 protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096 cytoskeleton organization#GO:0007010;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009197.1|UniProtKB=W5MS59 W5MS59 PTHR11711:SF357 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 1 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 LEPOC|Ensembl=ENSLOCG00000002441.1|UniProtKB=W5M3A6 W5M3A6 PTHR11588:SF247 TUBULIN TUBULIN BETA-4B CHAIN ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 tubulin#PC00228;cytoskeletal protein#PC00085 Huntington disease#P00029>Microtubule#P00780;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>beta-Tubulin#P00790 LEPOC|Ensembl=ENSLOCG00000016603.1|UniProtKB=W5NIP7 W5NIP7 PTHR45963:SF1 RE52028P SORTING NEXIN-3 phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;early endosome membrane#GO:0031901;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000012015.1|UniProtKB=W5N2E9 W5N2E9 PTHR36983:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001752.1|UniProtKB=W5M0W7 W5M0W7 PTHR15140:SF69 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE COFACTOR E-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016055.1|UniProtKB=W5NGM5 W5NGM5 PTHR37402:SF1 GRAM DOMAIN-CONTAINING PROTEIN 4 GRAM DOMAIN-CONTAINING PROTEIN 4 positive regulation of apoptotic process#GO:0043065;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017888.1|UniProtKB=W5NMY2 W5NMY2 PTHR24249:SF426 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR SI:DKEY-7C18.19 PROTEIN-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005591.1|UniProtKB=W5MEE3 W5MEE3 PTHR24366:SF39 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT, IG-LIKE AND TRANSMEMBRANE DOMAINS 2 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000016573.1|UniProtKB=W5NIL2 W5NIL2 PTHR47688:SF1 NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000005473.1|UniProtKB=W5MDZ5 W5MDZ5 PTHR12107:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-3 SUBUNIT transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;system process#GO:0003008;transmission of nerve impulse#GO:0019226;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;cell communication#GO:0007154;localization#GO:0051179;regulation of synaptic transmission, glutamatergic#GO:0051966;nervous system process#GO:0050877;regulation of signaling#GO:0023051;localization within membrane#GO:0051668;positive regulation of synaptic transmission#GO:0050806 cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;transmembrane transporter complex#GO:1902495;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794 voltage-gated ion channel#PC00241;transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000016841.1|UniProtKB=W5NJK8 W5NJK8 PTHR19282:SF41 TETRASPANIN TETRASPANIN-9 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006302.1|UniProtKB=W5MGV1 W5MGV1 PTHR21245:SF8 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN APOBEC1 COMPLEMENTATION FACTOR RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008498.1|UniProtKB=W5MPN3 W5MPN3 PTHR24104:SF58 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 2 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Alzheimer disease-presenilin pathway#P00004>HAC1#P00131 LEPOC|Ensembl=ENSLOCG00000000468.1|UniProtKB=W5LWK5 W5LWK5 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000010211.1|UniProtKB=W5MVU8 W5MVU8 PTHR24366:SF75 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEATS AND IMMUNOGLOBULIN LIKE DOMAINS 1 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000007666.1|UniProtKB=W5MLQ7 W5MLQ7 PTHR45899:SF6 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1-RELATED ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;enzyme regulator activity#GO:0030234;lipid binding#GO:0008289;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;phosphatidylinositol phosphate binding#GO:1901981;molecular function regulator activity#GO:0098772 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000006731.1|UniProtKB=W5MIE0 W5MIE0 PTHR22168:SF3 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26 LEPOC|Ensembl=ENSLOCG00000013827.1|UniProtKB=W5N8U4 W5N8U4 PTHR12296:SF16 DENN DOMAIN-CONTAINING PROTEIN 4 C-MYC PROMOTER-BINDING PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000011944.1|UniProtKB=W5N228 W5N228 PTHR19290:SF150 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED ATONAL BHLH TRANSCRIPTION FACTOR 1B binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000002774.1|UniProtKB=W5M4G2 W5M4G2 PTHR24412:SF255 KELCH PROTEIN KELCH-LIKE PROTEIN 21 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008594.1|UniProtKB=W5MPZ0 W5MPZ0 PTHR11653:SF12 PARVALBUMIN ALPHA PARVALBUMIN calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000013073.1|UniProtKB=W5N646 W5N646 PTHR16064:SF3 BTB POZ DOMAIN CONTAINING 7 BTB_POZ DOMAIN-CONTAINING PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000006414.1|UniProtKB=W5MH91 W5MH91 PTHR10218:SF217 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-15 GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111 G protein-coupled dopamine receptor signaling pathway#GO:0007212;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of membrane potential#GO:0042391;regulation of biological process#GO:0050789;action potential#GO:0001508;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;regulation of biological quality#GO:0065008 cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Wnt signaling pathway#P00057>Galpha#P01451;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826 LEPOC|Ensembl=ENSLOCG00000015224.1|UniProtKB=W5NDN1 W5NDN1 PTHR23042:SF48 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS BASIC HELIX-LOOP-HELIX ARNT-LIKE PROTEIN 2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000005629.1|UniProtKB=W5MEK7 W5MEK7 PTHR11864:SF0 PRE-MRNA-PROCESSING PROTEIN PRP40 PRE-MRNA-PROCESSING FACTOR 40 HOMOLOG A RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681 LEPOC|Ensembl=ENSLOCG00000005044.1|UniProtKB=W5MCG6 W5MCG6 PTHR12830:SF9 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;positive regulation of cell cycle process#GO:0090068;protein polyubiquitination#GO:0000209;regulation of organelle organization#GO:0033043;protein K11-linked ubiquitination#GO:0070979;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;regulation of chromosome separation#GO:1905818;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;regulation of mitotic metaphase/anaphase transition#GO:0030071;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic nuclear division#GO:0007088;positive regulation of mitotic cell cycle#GO:0045931;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of mitotic sister chromatid separation#GO:0010965;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000012552.1|UniProtKB=W5N4A5 W5N4A5 PTHR34531:SF1 ZGC:153352 CHROMOSOME 5 OPEN READING FRAME 34 LEPOC|Ensembl=ENSLOCG00000004492.1|UniProtKB=W5MAG2 W5MAG2 PTHR20855:SF107 ADIPOR/PROGESTIN RECEPTOR-RELATED MONOCYTE TO MACROPHAGE DIFFERENTIATION FACTOR 2 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018309.1|UniProtKB=W5NP51 W5NP51 PTHR24028:SF236 CADHERIN-87A PROTOCADHERIN ALPHA-C1 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000013195.1|UniProtKB=W5N6K8 W5N6K8 PTHR10037:SF223 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 4 SUBUNIT ALPHA monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081 metal ion transport#GO:0030001;membrane depolarization#GO:0051899;sensory perception of pain#GO:0019233;action potential#GO:0001508;sodium ion transport#GO:0006814;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;system process#GO:0003008;transport#GO:0006810 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000005350.1|UniProtKB=W5MDK8 W5MDK8 PTHR24085:SF2 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 3 sequence-specific double-stranded DNA binding#GO:1990837;transcription factor binding#GO:0008134;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;nuclear receptor binding#GO:0016922;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 response to peptide hormone#GO:0043434;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 C4 zinc finger nuclear receptor#PC00169;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012247.1|UniProtKB=W5N362 W5N362 PTHR43272:SF112 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 5 catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;organophosphate biosynthetic process#GO:0090407;positive regulation of cellular process#GO:0048522;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;acyl-CoA metabolic process#GO:0006637;nucleoside phosphate biosynthetic process#GO:1901293;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;regulation of localization#GO:0032879;regulation of transport#GO:0051049 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000006930.1|UniProtKB=W5MJ22 W5MJ22 PTHR11481:SF132 IMMUNOGLOBULIN FC RECEPTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;immune response#GO:0006955;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007517.1|UniProtKB=W5ML63 W5ML63 PTHR10796:SF60 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005409.1|UniProtKB=W5MDT0 W5MDT0 PTHR11140:SF0 PRE-MRNA SPLICING FACTOR PRP8 PRE-MRNA-PROCESSING-SPLICING FACTOR 8 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;U5 snRNP#GO:0005682;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000009932.1|UniProtKB=W5MUT3 W5MUT3 PTHR23341:SF1 HIGH MOBILITY GROUP PROTEINS HMG-A AND C HIGH MOBILITY GROUP PROTEIN HMG-I_HMG-Y DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000010724.1|UniProtKB=W5MXN8 W5MXN8 PTHR13116:SF10 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;EMC complex#GO:0072546 LEPOC|Ensembl=ENSLOCG00000002565.1|UniProtKB=W5M3R7 W5M3R7 PTHR11824:SF20 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000005658.1|UniProtKB=W5MEM1 W5MEM1 PTHR23235:SF16 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 Huntington disease#P00029>Sp1#P00803;Gonadotropin-releasing hormone receptor pathway#P06664>SP1#P06846;CCKR signaling map#P06959>SP1#P07203 LEPOC|Ensembl=ENSLOCG00000009630.1|UniProtKB=W5MTQ8 W5MTQ8 PTHR23105:SF54 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 2 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;snRNA processing#GO:0016180;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013397.1|UniProtKB=W5N7A2 W5N7A2 PTHR23268:SF102 T-CELL RECEPTOR BETA CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013459.1|UniProtKB=W5N7J6 W5N7J6 PTHR24083:SF42 NUCLEAR HORMONE RECEPTOR HEPATOCYTE NUCLEAR FACTOR 4-GAMMA signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000016215.1|UniProtKB=W5NH83 W5NH83 PTHR44499:SF1 JOUBERIN JOUBERIN plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000015868.1|UniProtKB=W5NFX8 W5NFX8 PTHR24103:SF673 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 54 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003324.1|UniProtKB=W5M6C3 W5M6C3 PTHR21545:SF10 TRANSCRIPTION FACTOR MLR1/2 LIGAND-DEPENDENT NUCLEAR RECEPTOR COREPRESSOR-LIKE PROTEIN regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011660.1|UniProtKB=W5N118 W5N118 PTHR16231:SF0 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 8 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209;signal transduction#GO:0007165;cellular process#GO:0009987;response to tumor necrosis factor#GO:0034612;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000013270.1|UniProtKB=W5N6U5 W5N6U5 PTHR11711:SF110 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 4 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 LEPOC|Ensembl=ENSLOCG00000008553.1|UniProtKB=W5MPU5 W5MPU5 PTHR16320:SF9 SPHINGOMYELINASE FAMILY MEMBER SPHINGOMYELIN PHOSPHODIESTERASE 5 phospholipid metabolic process#GO:0006644;sphingomyelin metabolic process#GO:0006684;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008343.1|UniProtKB=W5MP22 W5MP22 PTHR14571:SF13 HISTONE-LYSINE N-METHYLTRANSFERASE SET-26-RELATED PHD FINGER PROTEIN 13 binding#GO:0005488;chromatin binding#GO:0003682 organelle fission#GO:0048285;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000002101.1|UniProtKB=W5M231 W5M231 PTHR48012:SF17 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCKR#P00311 LEPOC|Ensembl=ENSLOCG00000013607.1|UniProtKB=W5N831 W5N831 PTHR23239:SF347 INTERMEDIATE FILAMENT KERATIN 93-RELATED organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000004560.1|UniProtKB=W5MAQ0 W5MAQ0 PTHR13356:SF3 OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED SOSS COMPLEX SUBUNIT B1 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;response to radiation#GO:0009314;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;response to ionizing radiation#GO:0010212;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000000465.1|UniProtKB=W5LWK0 W5LWK0 USB1 PTHR13522:SF3 U6 SNRNA PHOSPHODIESTERASE 1 U6 SNRNA PHOSPHODIESTERASE 1 RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007620.1|UniProtKB=W5MLI6 W5MLI6 PTHR23255:SF66 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1-LIKE transferase activity#GO:0016740;transforming growth factor beta receptor activity#GO:0005024;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;molecular transducer activity#GO:0060089 cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;angiogenesis#GO:0001525;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;transforming growth factor beta receptor signaling pathway#GO:0007179;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;dorsal/ventral pattern formation#GO:0009953;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;BMP signaling pathway#GO:0030509;cellular response to transforming growth factor beta stimulus#GO:0071560;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;pattern specification process#GO:0007389;response to transforming growth factor beta#GO:0071559;regionalization#GO:0003002;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;cellular developmental process#GO:0048869;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;developmental process#GO:0032502 signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 LEPOC|Ensembl=ENSLOCG00000016894.1|UniProtKB=W5NJU1 W5NJU1 PTHR37412:SF2 C2 DOMAIN-CONTAINING PROTEIN 5 C2 DOMAIN-CONTAINING PROTEIN 5 phospholipid binding#GO:0005543;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;lipid binding#GO:0008289;cation binding#GO:0043169 protein localization to cell periphery#GO:1990778;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;intracellular protein transmembrane transport#GO:0065002;positive regulation of vesicle fusion#GO:0031340;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of transport#GO:0051050;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cellular component organization#GO:0051130;transmembrane transport#GO:0055085;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;regulation of protein localization#GO:0032880;protein transport#GO:0015031;protein localization to membrane#GO:0072657;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;localization within membrane#GO:0051668;localization#GO:0051179;regulation of establishment of protein localization#GO:0070201;regulation of transmembrane transport#GO:0034762;protein localization to plasma membrane#GO:0072659;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000018253.1|UniProtKB=W5NNZ5 W5NNZ5 PTHR24248:SF54 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-1 ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227 system process#GO:0003008;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of anatomical structure size#GO:0090066;biological regulation#GO:0065007;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;adrenergic receptor signaling pathway#GO:0071875;regulation of biological quality#GO:0065008;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;signaling#GO:0023052;vasodilation#GO:0042311;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Beta1 adrenergic receptor signaling pathway#P04377>Beta1#P04433 LEPOC|Ensembl=ENSLOCG00000011583.1|UniProtKB=W5N0S2 W5N0S2 PTHR11861:SF11 MELANOCYTE PROTEIN PMEL 17-RELATED TRANSMEMBRANE GLYCOPROTEIN NMB protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000000700.1|UniProtKB=W5LXC1 W5LXC1 PTHR11599:SF6 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-2 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634 protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001747.1|UniProtKB=W5M0W0 W5M0W0 PTHR12294:SF3 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 2, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 mitochondrial calcium ion homeostasis#GO:0051560;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular process#GO:0009987;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003 cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;transporter complex#GO:1990351;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000012733.1|UniProtKB=W5N4W6 W5N4W6 PTHR11699:SF209 ALDEHYDE DEHYDROGENASE-RELATED RETINALDEHYDE DEHYDROGENASE 3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 regulation of hormone levels#GO:0010817;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;isoprenoid biosynthetic process#GO:0008299;terpenoid metabolic process#GO:0006721;oxoacid metabolic process#GO:0043436;regulation of biological quality#GO:0065008;isoprenoid metabolic process#GO:0006720;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;aldehyde catabolic process#GO:0046185;biological regulation#GO:0065007;biosynthetic process#GO:0009058;terpenoid biosynthetic process#GO:0016114;lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;diterpenoid biosynthetic process#GO:0016102;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;monocarboxylic acid biosynthetic process#GO:0072330;retinoid metabolic process#GO:0001523 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000003248.1|UniProtKB=W5M630 W5M630 PTHR22894:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF170 LEPOC|Ensembl=ENSLOCG00000005737.1|UniProtKB=W5MEX1 W5MEX1 PTHR10845:SF277 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 20 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;negative regulation of cell communication#GO:0010648 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000008845.1|UniProtKB=W5MQX5 W5MQX5 PTHR47695:SF4 PID DOMAIN-CONTAINING PROTEIN DISABLED HOMOLOG 1 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;generation of neurons#GO:0048699;neuron migration#GO:0001764;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;cellular process#GO:0009987;cell differentiation#GO:0030154;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cell motility#GO:0048870;nervous system development#GO:0007399 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005761.1|UniProtKB=W5MEZ9 W5MEZ9 PTHR46770:SF1 HOMEOBOX PROTEIN ORTHOPEDIA HOMEOBOX PROTEIN ORTHOPEDIA DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 neurogenesis#GO:0022008;system development#GO:0048731;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;cellular process#GO:0009987 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000011097.1|UniProtKB=W5MZ28 W5MZ28 PTHR24416:SF53 TYROSINE-PROTEIN KINASE RECEPTOR PLATELET-DERIVED GROWTH FACTOR RECEPTOR BETA protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 angiogenesis#GO:0001525;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell chemotaxis#GO:0060326;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;chemotaxis#GO:0006935;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;locomotion#GO:0040011;cell motility#GO:0048870;regulation of cellular process#GO:0050794;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;developmental process#GO:0032502;regulation of cell migration#GO:0030334;tube development#GO:0035295;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cell migration#GO:0016477;multicellular organismal process#GO:0032501;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 PDGF signaling pathway#P00047>PDGF receptor B#P01156;Angiogenesis#P00005>PDGFR#P00230 LEPOC|Ensembl=ENSLOCG00000006430.1|UniProtKB=W5MHE8 W5MHE8 CACNA1A PTHR45628:SF3 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT P_Q-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1A metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245 signaling#GO:0023052;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;anterograde trans-synaptic signaling#GO:0098916;import across plasma membrane#GO:0098739;regulation of biological process#GO:0050789;calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588;chemical synaptic transmission#GO:0007268;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;calcium ion transmembrane import into cytosol#GO:0097553;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810 membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;cell body#GO:0044297;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351 voltage-gated ion channel#PC00241 Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;GABA-B receptor II signaling#P05731>Ca channel#P05753;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051 LEPOC|Ensembl=ENSLOCG00000016572.1|UniProtKB=W5NIL0 W5NIL0 PTHR15344:SF3 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 3 small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089;regulation of anatomical structure size#GO:0090066;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;Rho protein signal transduction#GO:0007266;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;small GTPase-mediated signal transduction#GO:0007264;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;positive regulation of cell projection organization#GO:0031346;intracellular signal transduction#GO:0035556;regulation of cell projection assembly#GO:0060491;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004705.1|UniProtKB=W5MB78 W5MB78 PTHR15326:SF8 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC SPERMATOGENESIS-ASSOCIATED PROTEIN 2 signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to external stimulus#GO:0032101;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to cytokine stimulus#GO:0060759;regulation of programmed cell death#GO:0043067;regulation of cytokine-mediated signaling pathway#GO:0001959;regulation of defense response#GO:0031347;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;regulation of signaling#GO:0023051;regulation of response to stress#GO:0080134 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002038.1|UniProtKB=W5M1V5 W5M1V5 PTHR24219:SF3 LIM DOMAIN-CONTAINING PROTEIN JUB LIM DOMAIN-CONTAINING PROTEIN 1 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of response to stimulus#GO:0048583;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of hippo signaling#GO:0035330;negative regulation of metabolic process#GO:0009892;regulation of signaling#GO:0023051;negative regulation of translation#GO:0017148;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331 intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membrane-bounded organelle#GO:0043227;P-body#GO:0000932;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;cell junction#GO:0030054;adherens junction#GO:0005912;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell-cell junction#GO:0005911;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000010056.1|UniProtKB=W5MV95 W5MV95 PTHR16795:SF13 LIMBIN/ELLIS-VAN CREVELD PROTEIN EVC COMPLEX MEMBER EVC cell surface receptor signaling pathway#GO:0007166;smoothened signaling pathway#GO:0007224;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;membrane#GO:0016020;cell periphery#GO:0071944;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 LEPOC|Ensembl=ENSLOCG00000002684.1|UniProtKB=W5M463 W5M463 PTHR11455:SF9 CRYPTOCHROME CRYPTOCHROME CIRCADIAN REGULATOR 5 lyase activity#GO:0016829;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;carbon-carbon lyase activity#GO:0016830;DNA binding#GO:0003677;ion binding#GO:0043167;deoxyribodipyrimidine photo-lyase activity#GO:0003904;anion binding#GO:0043168;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 DNA photolyase#PC00014 Circadian clock system#P00015>cry#G01497;Circadian clock system#P00015>cry#G01501;Circadian clock system#P00015>Cry#P00505 LEPOC|Ensembl=ENSLOCG00000015134.1|UniProtKB=W5NDB7 W5NDB7 PTHR45686:SF1 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 3 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012521.1|UniProtKB=W5N466 W5N466 PTHR11537:SF40 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY V MEMBER 2 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108 metal ion transport#GO:0030001;action potential#GO:0001508;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000004995.1|UniProtKB=W5MCB6 W5MCB6 PTHR12233:SF5 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26B cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;cytosolic transport#GO:0016482;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;retromer complex#GO:0030904;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012136.1|UniProtKB=W5N2S6 W5N2S6 PTHR24058:SF103 DUAL SPECIFICITY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018167.1|UniProtKB=W5NNQ9 W5NNQ9 PTHR11786:SF3 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE, PINEAL GLAND ISOZYME NAT-3-RELATED N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000006440.1|UniProtKB=W5MHC1 W5MHC1 PTHR10969:SF14 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 ALPHA ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515;lipid binding#GO:0008289;microtubule binding#GO:0008017;binding#GO:0005488;enzyme binding#GO:0019899 cellular response to stress#GO:0033554;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;response to stress#GO:0006950;macroautophagy#GO:0016236;cellular component assembly#GO:0022607 autophagosome#GO:0005776;intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000010293.1|UniProtKB=W5MW52 W5MW52 PTHR23122:SF34 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 4 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;adherens junction#GO:0005912;anchoring junction#GO:0070161 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015606.1|UniProtKB=W5NF04 W5NF04 PTHR10529:SF341 AP COMPLEX SUBUNIT MU AP-3 COMPLEX SUBUNIT MU-2 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vacuolar transport#GO:0007034 Golgi apparatus#GO:0005794;AP-type membrane coat adaptor complex#GO:0030119;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009944.1|UniProtKB=W5MUV4 W5MUV4 PTHR10556:SF31 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE VERY-LONG-CHAIN ENOYL-COA REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000018321.1|UniProtKB=W5NP63 W5NP63 PTHR10489:SF686 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 5-LIKE-RELATED signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;locomotion#GO:0040011;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;cell communication#GO:0007154;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017799.1|UniProtKB=W5NMP4 W5NMP4 PTHR10270:SF328 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-1 transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000004904.1|UniProtKB=W5MBY8 W5MBY8 PTHR46612:SF1 XYLOSIDE XYLOSYLTRANSFERASE 1 XYLOSIDE XYLOSYLTRANSFERASE 1 glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000014220.1|UniProtKB=W5NA54 W5NA54 PTHR11953:SF1 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP46 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 gene expression#GO:0010467;RNA processing#GO:0006396;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;snRNA 3'-end processing#GO:0034472;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;snRNA processing#GO:0016180;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA metabolic process#GO:0016073 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000008538.1|UniProtKB=W5MPS7 W5MPS7 PTHR24291:SF216 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450, FAMILY 4, SUBFAMILY B, POLYPEPTIDE 7 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002284.1|UniProtKB=W5M2R7 W5M2R7 PTHR11461:SF30 SERINE PROTEASE INHIBITOR, SERPIN HEPARIN COFACTOR 2 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>HCII#P00456 LEPOC|Ensembl=ENSLOCG00000004537.1|UniProtKB=W5MAL8 W5MAL8 PTHR23235:SF49 KRUEPPEL-LIKE TRANSCRIPTION FACTOR WILMS TUMOR PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000010894.1|UniProtKB=W5MY95 W5MY95 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005451.1|UniProtKB=W5MDW7 W5MDW7 PTHR19308:SF53 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN CERAMIDE TRANSFER PROTEIN intracellular transport#GO:0046907;lipid localization#GO:0010876;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;lipid transport#GO:0006869;ceramide transport#GO:0035627 LEPOC|Ensembl=ENSLOCG00000012026.1|UniProtKB=W5N2D8 W5N2D8 PTHR22699:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 16 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 16 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007719.1|UniProtKB=W5MLW5 W5MLW5 PTHR24193:SF86 ANKYRIN REPEAT PROTEIN GA-BINDING PROTEIN SUBUNIT BETA-2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006729.1|UniProtKB=W5MIB5 W5MIB5 PTHR20859:SF98 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON GAMMA RECEPTOR 2 PRECURSOR-RELATED immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005249.1|UniProtKB=W5MD66 W5MD66 PTHR24027:SF273 CADHERIN-23 CADHERIN-8 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell migration#GO:0016477;cellular component assembly#GO:0022607;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell adhesion#GO:0007155 axon#GO:0030424;extracellular region#GO:0005576;anchoring junction#GO:0070161;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron projection terminus#GO:0044306;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;axon terminus#GO:0043679;membrane#GO:0016020;cell-cell junction#GO:0005911;neuron projection#GO:0043005;presynapse#GO:0098793;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000001982.1|UniProtKB=W5M1N4 W5M1N4 PTHR10334:SF62 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR R3HDML extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000592.1|UniProtKB=W5LX15 W5LX15 PTHR24416:SF631 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE STYK1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000840.1|UniProtKB=W5LXT4 W5LXT4 PTHR10131:SF146 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR tumor necrosis factor receptor superfamily binding#GO:0032813;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;molecular adaptor activity#GO:0060090;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;ubiquitin-like protein transferase activity#GO:0019787 regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of signal transduction#GO:0009967;response to peptide#GO:1901652;tumor necrosis factor-mediated signaling pathway#GO:0033209;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;response to cytokine#GO:0034097;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;response to tumor necrosis factor#GO:0034612;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of intracellular signal transduction#GO:1902533 membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008200.1|UniProtKB=W5MNJ7 W5MNJ7 PTHR22883:SF8 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC1 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 response to other organism#GO:0051707;defense response to other organism#GO:0098542;immune response#GO:0006955;establishment of protein localization#GO:0045184;defense response to symbiont#GO:0140546;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;establishment of localization#GO:0051234;innate immune response#GO:0045087;protein targeting to membrane#GO:0006612;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;protein targeting#GO:0006605;antiviral innate immune response#GO:0140374;defense response to virus#GO:0051607;localization#GO:0051179;response to virus#GO:0009615;cellular localization#GO:0051641;localization within membrane#GO:0051668;immune system process#GO:0002376 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017754.1|UniProtKB=W5NMJ9 W5NMJ9 PTHR24241:SF195 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR 2A-LIKE G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017476.1|UniProtKB=W5NLS2 W5NLS2 PTHR45629:SF13 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;DNA translocase activity#GO:0015616;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000012990.1|UniProtKB=W5N5T8 W5N5T8 PTHR11829:SF385 FORKHEAD BOX PROTEIN FORKHEAD BOX Q1A-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000013673.1|UniProtKB=W5N899 W5N899 PTHR23119:SF33 DISCS LARGE DISKS LARGE HOMOLOG 4 structural constituent of synapse#GO:0098918;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;structural molecule activity#GO:0005198 intracellular protein localization#GO:0008104;developmental process#GO:0032502;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;membrane organization#GO:0061024;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036;system development#GO:0048731;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;localization within membrane#GO:0051668;synapse organization#GO:0050808;establishment or maintenance of bipolar cell polarity#GO:0061245;protein localization to cell junction#GO:1902414;establishment or maintenance of apical/basal cell polarity#GO:0035088;trans-synaptic signaling#GO:0099537;postsynapse organization#GO:0099173;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;chemical synaptic transmission#GO:0007268;multicellular organism development#GO:0007275;protein localization to synapse#GO:0035418;cellular component organization or biogenesis#GO:0071840;nervous system development#GO:0007399;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;receptor clustering#GO:0043113;cell adhesion#GO:0007155;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043 synaptic membrane#GO:0097060;neuromuscular junction#GO:0031594;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279 scaffold/adaptor protein#PC00226 Huntington disease#P00029>PSD-95#P00789 LEPOC|Ensembl=ENSLOCG00000013667.1|UniProtKB=W5N8A9 W5N8A9 PTHR46357:SF1 TRANSCRIPTIONAL REGULATOR ATRX CHROMATIN REMODELER ATRX DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;replication fork processing#GO:0031297;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;DNA replication#GO:0006260;cellular process#GO:0009987;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;heterochromatin#GO:0000792 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000002965.1|UniProtKB=W5M533 W5M533 PTHR46427:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1 STRUCTURE-SPECIFIC ENDONUCLEASE ANKLE1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;resolution of meiotic recombination intermediates#GO:0000712;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000008949.1|UniProtKB=W5MR94 W5MR94 QTRT1 PTHR43530:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007914.1|UniProtKB=W5MMK2 W5MMK2 PTHR45622:SF75 UBIQUITIN-PROTEIN LIGASE E3A-RELATED X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 modification-dependent macromolecule catabolic process#GO:0043632;nervous system process#GO:0050877;microtubule-based transport#GO:0099111;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;cilium organization#GO:0044782;cellular localization#GO:0051641;protein modification by small protein conjugation#GO:0032446;cellular component organization#GO:0016043;cell projection organization#GO:0030030;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;protein ubiquitination#GO:0016567;sensory perception#GO:0007600;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;localization#GO:0051179;modification-dependent protein catabolic process#GO:0019941;sensory perception of light stimulus#GO:0050953;protein modification process#GO:0036211;primary metabolic process#GO:0044238;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;catabolic process#GO:0009056;visual perception#GO:0007601;transport#GO:0006810;intracellular transport#GO:0046907;ubiquitin-dependent protein catabolic process#GO:0006511;system process#GO:0003008;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;macromolecule metabolic process#GO:0043170;plasma membrane bounded cell projection organization#GO:0120036;post-translational protein modification#GO:0043687;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501 Golgi apparatus#GO:0005794;9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007575.1|UniProtKB=W5MLE4 W5MLE4 PTHR11347:SF74 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4A phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000009098.1|UniProtKB=W5MRU1 W5MRU1 PTHR47219:SF7 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE RAB GTPASE-ACTIVATING PROTEIN 1-LIKE enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677 biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of biological process#GO:0050789 GTPase-activating protein#PC00257;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000001459.1|UniProtKB=W5LZX1 W5LZX1 PTHR46571:SF1 SORTING NEXIN-8 SORTING NEXIN-8 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cytosolic transport#GO:0016482;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002445.1|UniProtKB=W5M3B1 W5M3B1 PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;amidase activity#GO:0004040;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000006574.1|UniProtKB=W5MHS5 W5MHS5 PTHR20886:SF8 VANG-LIKE PROTEIN VANG-LIKE PROTEIN 1 morphogenesis of an epithelium#GO:0002009;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;epithelium development#GO:0060429;tissue development#GO:0009888;signal transduction#GO:0007165;cellular process#GO:0009987;tissue morphogenesis#GO:0048729;cell communication#GO:0007154;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004253.1|UniProtKB=W5M9M8 W5M9M8 PTHR24339:SF29 HOMEOBOX PROTEIN EMX-RELATED GS HOMEOBOX 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;animal organ development#GO:0048513;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009824.1|UniProtKB=W5MUE5 W5MUE5 PTHR22749:SF14 RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE RIBOFLAVIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;flavin-containing compound metabolic process#GO:0042726;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 Flavin biosynthesis#P02741>FAD synthetase#P02936;Flavin biosynthesis#P02741>Riboflavin kinase#P02934 LEPOC|Ensembl=ENSLOCG00000016669.1|UniProtKB=W5NIY6 W5NIY6 PTHR15720:SF13 GREB1-RELATED PROTEIN GREB1 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;epithelium development#GO:0060429 LEPOC|Ensembl=ENSLOCG00000017780.1|UniProtKB=W5NMM5 W5NMM5 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014108.1|UniProtKB=W5N9S2 W5N9S2 PTHR16290:SF4 TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 MRNA-DECAPPING ENZYME 1A RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA catabolic process#GO:0006401;RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;mRNA capping factor#PC00145 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000002249.1|UniProtKB=W5M2L4 W5M2L4 PTHR21314:SF0 QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 LEPOC|Ensembl=ENSLOCG00000014556.1|UniProtKB=W5NBB1 W5NBB1 PTHR15859:SF5 SETA BINDING PROTEIN 1 SH3KBP1-BINDING PROTEIN 1 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of response to stimulus#GO:0048584;regulation of cell communication#GO:0010646;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of signal transduction#GO:0009967;regulation of ERBB signaling pathway#GO:1901184;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000365.1|UniProtKB=W5LW91 W5LW91 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015722.1|UniProtKB=W5NFE4 W5NFE4 PTHR28647:SF2 UNIQUE CARTILAGE MATRIX-ASSOCIATED PROTEIN UNIQUE CARTILAGE MATRIX-ASSOCIATED PROTEIN embryo development#GO:0009790;multicellular organismal process#GO:0032501;system development#GO:0048731;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;developmental process#GO:0032502;embryo development ending in birth or egg hatching#GO:0009792;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 LEPOC|Ensembl=ENSLOCG00000007558.1|UniProtKB=W5MLC3 W5MLC3 PTHR15377:SF5 TRANSCRIPTION ELONGATION REGULATOR 1 TRANSCRIPTION ELONGATION REGULATOR 1-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000016035.1|UniProtKB=W5NGJ4 W5NGJ4 PTHR13902:SF48 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010743.1|UniProtKB=W5MXQ6 W5MXQ6 PTHR48033:SF3 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012422.1|UniProtKB=W5N3V9 W5N3V9 PTHR45816:SF1 MIR DOMAIN-CONTAINING PROTEIN INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR LEPOC|Ensembl=ENSLOCG00000015415.1|UniProtKB=W5NEB5 W5NEB5 PTHR11347:SF104 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;cyclic-nucleotide phosphodiesterase activity#GO:0004112 regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000013335.1|UniProtKB=W5N731 W5N731 PTHR11267:SF125 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX21 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;mononuclear cell migration#GO:0071674;immune system process#GO:0002376;cell migration#GO:0016477;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;lymphocyte migration#GO:0072676;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;leukocyte migration#GO:0050900;cell fate specification#GO:0001708;developmental process#GO:0032502 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 LEPOC|Ensembl=ENSLOCG00000017286.1|UniProtKB=W5NL75 W5NL75 PTHR24249:SF417 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 11 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000047.1|UniProtKB=W5LV99 W5LV99 PTHR14819:SF5 GTP-BINDING INTERFERON-INDUCED VERY LARGE GTPASE 1 LEPOC|Ensembl=ENSLOCG00000010362.1|UniProtKB=W5MWF0 W5MWF0 PTHR16560:SF2 ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;enzyme binding#GO:0019899;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function inhibitor activity#GO:0140678;lipoprotein particle receptor binding#GO:0070325;signaling receptor inhibitor activity#GO:0030547;protein binding#GO:0005515 regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;negative regulation of transport#GO:0051051;regulation of receptor-mediated endocytosis#GO:0048259;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;cis-Golgi network#GO:0005801;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle lumen#GO:0043233;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;rough endoplasmic reticulum#GO:0005791;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000018303.1|UniProtKB=W5NP45 W5NP45 PTHR21428:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893 nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000008432.1|UniProtKB=W5MPE3 W5MPE3 PTHR45706:SF3 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 21 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000000948.1|UniProtKB=W5LY48 W5LY48 PTHR46780:SF22 PROTEIN EVA-1 PROTEIN EVA-1 HOMOLOG A LEPOC|Ensembl=ENSLOCG00000015790.1|UniProtKB=W5NFN1 W5NFN1 PTHR22973:SF11 LD35087P GOLGI RESIDENT PROTEIN GCP60 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005455.1|UniProtKB=W5MDW8 W5MDW8 PTHR45762:SF14 ZINC FINGER RNA-BINDING PROTEIN SI:CH211-197H24.6 double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011105.1|UniProtKB=W5MZ34 W5MZ34 PTHR46173:SF1 CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL RNA binding#GO:0003723;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;tRNA 3'-end processing#GO:0042780;mitochondrial RNA 3'-end processing#GO:0000965 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017216.1|UniProtKB=W5NKX6 W5NKX6 PTHR10816:SF11 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000003604.1|UniProtKB=W5M7B1 W5M7B1 PTHR13453:SF1 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000004671.1|UniProtKB=W5MB38 W5MB38 PTHR13341:SF6 MIR-INTERACTING SAPOSIN-LIKE PROTEIN PROTEIN CANOPY HOMOLOG 2 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008302.1|UniProtKB=W5MNX8 W5MNX8 PTHR19232:SF1 CENTROCORTIN FAMILY MEMBER CEREBELLAR DEGENERATION-RELATED PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000004446.1|UniProtKB=W5MAD9 W5MAD9 PTHR19384:SF66 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE 3 ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;oxidoreductase activity, acting on NAD(P)H#GO:0016651;ribonucleotide binding#GO:0032553;monooxygenase activity#GO:0004497;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363 regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;carboxylic acid metabolic process#GO:0019752;response to endogenous stimulus#GO:0009719;small molecule catabolic process#GO:0044282;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;regulation of biological quality#GO:0065008;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607;arginine metabolic process#GO:0006525;intracellular signaling cassette#GO:0141124;response to lipid#GO:0033993;response to chemical#GO:0042221;metabolic process#GO:0008152;response to lipopolysaccharide#GO:0032496;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;circulatory system process#GO:0003013;response to bacterium#GO:0009617;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;carboxylic acid catabolic process#GO:0046395;regulation of blood pressure#GO:0008217;amino acid metabolic process#GO:0006520;response to other organism#GO:0051707;biosynthetic process#GO:0009058;biological regulation#GO:0065007;proteinogenic amino acid metabolic process#GO:0170039;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;system process#GO:0003008;response to external stimulus#GO:0009605 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Angiogenesis#P00005>eNOS#P00210;Endothelin signaling pathway#P00019>eNOS#P00578;PI3 kinase pathway#P00048>NOS#P01205;VEGF signaling pathway#P00056>eNOS#P01422;Interleukin signaling pathway#P00036>eNOS#P00986 LEPOC|Ensembl=ENSLOCG00000009852.1|UniProtKB=W5MUI8 W5MUI8 PTHR10218:SF213 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-14 ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of membrane potential#GO:0042391;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;response to oxygen-containing compound#GO:1901700;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;action potential#GO:0001508;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 heterotrimeric G-protein#PC00117;G-protein#PC00020 PI3 kinase pathway#P00048>Galpha#P01199;Wnt signaling pathway#P00057>Galpha#P01451;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Endothelin signaling pathway#P00019>Gq#P00586;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073 LEPOC|Ensembl=ENSLOCG00000005011.1|UniProtKB=W5MCE3 W5MCE3 PTHR46489:SF2 STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL ISOFORM X1 binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934;alcohol binding#GO:0043178;steroid binding#GO:0005496;lipid binding#GO:0008289;cholesterol binding#GO:0015485 regulation of lipid biosynthetic process#GO:0046890;lipid transport#GO:0006869;regulation of steroid biosynthetic process#GO:0050810;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;regulation of metabolic process#GO:0019222;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of localization#GO:0051234;sterol transport#GO:0015918;regulation of biosynthetic process#GO:0009889;intracellular transport#GO:0046907;transport#GO:0006810;regulation of cellular process#GO:0050794;intracellular sterol transport#GO:0032366;regulation of biological process#GO:0050789;localization#GO:0051179;cellular localization#GO:0051641;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;regulation of lipid metabolic process#GO:0019216 LEPOC|Ensembl=ENSLOCG00000010043.1|UniProtKB=W5MV78 W5MV78 PTHR12447:SF39 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13C molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;biological regulation#GO:0065007;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of endocytosis#GO:0030100 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;late endosome#GO:0005770;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000464.1|UniProtKB=W5LWK1 W5LWK1 PTHR14241:SF1 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 LEPOC|Ensembl=ENSLOCG00000011494.1|UniProtKB=W5N0G5 W5N0G5 PTHR14107:SF5 WD REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 20 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;peptidase activator activity#GO:0016504 negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of catabolic process#GO:0009894;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of cellular process#GO:0048523;negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule metabolic process#GO:0010605 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000332.1|UniProtKB=W5LW53 W5LW53 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000064.1|UniProtKB=W5LVB7 W5LVB7 PTHR15298:SF17 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000008380.1|UniProtKB=W5MP89 W5MP89 PTHR15696:SF7 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 NONSENSE-MEDIATED MRNA DECAY FACTOR binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;RNA binding#GO:0003723;DNA binding#GO:0003677 negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003644.1|UniProtKB=W5M7H2 W5M7H2 PTHR11848:SF166 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 11 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;response to transforming growth factor beta#GO:0071559;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000009262.1|UniProtKB=W5MSE9 W5MSE9 CEP350 PTHR13958:SF3 CENTROSOME-ASSOCIATED PROTEIN 350 CAP-GLY DOMAIN-CONTAINING PROTEIN-RELATED non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000009759.1|UniProtKB=W5MU62 W5MU62 PTHR11153:SF3 SIDEROFLEXIN SIDEROFLEXIN-4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810;intracellular transport#GO:0046907;mitochondrial transport#GO:0006839;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000004991.1|UniProtKB=W5MCA8 W5MCA8 PTHR17972:SF0 NUCLEOLAR RNA-ASSOCIATED PROTEIN NUCLEOLAR PROTEIN 6 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014766.1|UniProtKB=W5NC21 W5NC21 PTHR22776:SF4 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PROTEOLIPID PROTEIN 2 immune system process#GO:0002376;immune response#GO:0006955;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003801.1|UniProtKB=W5M833 W5M833 PTHR24391:SF26 HISTONE H4 TRANSCRIPTION FACTOR-RELATED HISTONE H4 TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008956.1|UniProtKB=W5MRA7 W5MRA7 PTHR18947:SF36 HOOK PROTEINS PROTEIN HOOK HOMOLOG 1 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 microtubule-based process#GO:0007017;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;cytoskeleton organization#GO:0007010;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;localization#GO:0051179;cytoplasmic microtubule organization#GO:0031122;cellular component organization#GO:0016043 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017096.1|UniProtKB=W5NKG7 W5NKG7 COQ3 PTHR43464:SF104 METHYLTRANSFERASE UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;ketone metabolic process#GO:0042180;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000015968.1|UniProtKB=W5NGA2 W5NGA2 PTHR24410:SF27 HL07962P-RELATED BTB DOMAIN CONTAINING 3 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011801.1|UniProtKB=W5N1K1 W5N1K1 PTHR45664:SF11 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B3 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;skeletal system morphogenesis#GO:0048705;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anterior/posterior pattern specification#GO:0009952;embryo development#GO:0009790;skeletal system development#GO:0001501;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000001066.1|UniProtKB=W5LYJ4 W5LYJ4 PTHR13017:SF0 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE-RELATED METHENYLTETRAHYDROFOLATE SYNTHASE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000005180.1|UniProtKB=W5MCZ4 W5MCZ4 PTHR24061:SF441 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 2.1-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011644.1|UniProtKB=W5N114 W5N114 PTHR10672:SF4 ADDUCIN ALPHA-ADDUCIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;regulation of cell development#GO:0060284;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;regulation of protein depolymerization#GO:1901879;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of actin filament depolymerization#GO:0030834;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein-containing complex assembly#GO:0031333;regulation of epithelial cell differentiation#GO:0030856;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;positive regulation of cell differentiation#GO:0045597;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008 plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000017479.1|UniProtKB=W5NLS5 W5NLS5 PTHR10614:SF2 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 4 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159 response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;response to endogenous stimulus#GO:0009719;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular response to endogenous stimulus#GO:0071495;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020 scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899 LEPOC|Ensembl=ENSLOCG00000001727.1|UniProtKB=W5M0T5 W5M0T5 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000014487.1|UniProtKB=W5NB19 W5NB19 PTHR16768:SF4 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A ACTIN-ASSOCIATED PROTEIN FAM107A ISOFORM X1 regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;actin filament polymerization#GO:0030041;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;actin filament bundle organization#GO:0061572;regulation of organelle organization#GO:0033043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;protein polymerization#GO:0051258;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;actin filament bundle#GO:0032432;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;actomyosin#GO:0042641;neuron projection#GO:0043005;membraneless organelle#GO:0043228;cell junction#GO:0030054;stress fiber#GO:0001725;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000005496.1|UniProtKB=W5ME23 W5ME23 PTHR45973:SF36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED CENTRIOLIN phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012713.1|UniProtKB=W5N4T6 W5N4T6 PTHR16056:SF18 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 3 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;spindle pole#GO:0000922;mitochondrion#GO:0005739;microtubule#GO:0005874;spindle microtubule#GO:0005876;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;spindle#GO:0005819;cytoskeleton#GO:0005856 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000012849.1|UniProtKB=W5N5A6 W5N5A6 PTHR10605:SF53 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 2 catalytic activity#GO:0003824;deacylase activity#GO:0160215;transferase activity#GO:0016740;deacetylase activity#GO:0019213;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000002282.1|UniProtKB=W5M2Q4 W5M2Q4 PTHR24060:SF177 METABOTROPIC GLUTAMATE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066 regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012951.1|UniProtKB=W5N5P4 W5N5P4 PTHR10678:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome complex#GO:0000502;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000015622.1|UniProtKB=W5NF24 W5NF24 PTHR16133:SF4 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED ZINC TRANSPORTER ZIP9 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000011156.1|UniProtKB=W5MZ99 W5MZ99 PTHR12207:SF21 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 3 membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007232.1|UniProtKB=W5MK42 W5MK42 PTHR10266:SF3 CYTOCHROME C1 CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 Huntington disease#P00029>Cytochrome c#P00785;FAS signaling pathway#P00020>CytochromeC#P00620;ATP synthesis#P02721>Cyt bc1#P02799 LEPOC|Ensembl=ENSLOCG00000005765.1|UniProtKB=W5MF04 W5MF04 PTHR23059:SF4 CYSTEINE AND HISTIDINE-RICH PROTEIN 1 ZINC FINGER TRAF-TYPE-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010901.1|UniProtKB=W5MYB8 W5MYB8 PTHR10132:SF17 ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER EPSILON-SARCOGLYCAN cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000006592.1|UniProtKB=W5MHV4 W5MHV4 PTHR15937:SF3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 negative regulation of cellular process#GO:0048523;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000010313.1|UniProtKB=W5MW84 W5MW84 PTHR11702:SF43 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED GTP-BINDING PROTEIN 10 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000000470.1|UniProtKB=W5LWK7 W5LWK7 PTHR22883:SF348 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC18-B acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000866.1|UniProtKB=W5LXV8 W5LXV8 PTHR12752:SF2 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PDZ AND PLECKSTRIN HOMOLOGY DOMAINS 1 LEPOC|Ensembl=ENSLOCG00000013722.1|UniProtKB=W5N8G3 W5N8G3 PTHR43161:SF29 SORBITOL DEHYDROGENASE SORBITOL DEHYDROGENASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022 carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;hexose biosynthetic process#GO:0019319;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate catabolic process#GO:0016052 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000002032.1|UniProtKB=W5M1X2 W5M1X2 PTHR24223:SF187 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000005956.1|UniProtKB=W5MFN6 W5MFN6 PTHR31488:SF2 DPY-19-LIKE 1, LIKE (H. SAPIENS) C-MANNOSYLTRANSFERASE DPY19L4-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000008081.1|UniProtKB=W5MN57 W5MN57 PTHR10907:SF47 REGUCALCIN REGUCALCIN catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of calcium-mediated signaling#GO:0050848;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 esterase#PC00097;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000539.1|UniProtKB=W5LWT9 W5LWT9 PTHR23266:SF420 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000008168.1|UniProtKB=W5MNF3 W5MNF3 PTHR11360:SF239 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 14 monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003327.1|UniProtKB=W5M6F4 W5M6F4 PTHR45656:SF23 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 3 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000008876.1|UniProtKB=W5MR02 W5MR02 PTHR23063:SF57 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000005964.1|UniProtKB=W5MFP0 W5MFP0 PTHR19367:SF18 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 18 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010109.1|UniProtKB=W5MVG0 W5MVG0 PTHR18935:SF6 GOLGIN SUBFAMILY A MEMBER 4-LIKE ISOFORM X1 JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;GABA receptor binding#GO:0050811 LEPOC|Ensembl=ENSLOCG00000006570.1|UniProtKB=W5MHS1 W5MHS1 PTHR31266:SF4 TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A FAMILY MEMBER TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A LEPOC|Ensembl=ENSLOCG00000002439.1|UniProtKB=W5M3B7 W5M3B7 PTHR10539:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;intracellular protein-containing complex#GO:0140535;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Parkinson disease#P00049>19S proteasome#P01209 LEPOC|Ensembl=ENSLOCG00000001738.1|UniProtKB=W5M0V0 W5M0V0 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED SI:DKEYP-69E1.8 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000008467.1|UniProtKB=W5MPJ1 W5MPJ1 PTHR31598:SF1 IQ DOMAIN-CONTAINING PROTEIN D DYNEIN REGULATORY COMPLEX SUBUNIT 10 LEPOC|Ensembl=ENSLOCG00000000120.1|UniProtKB=W5LVK5 W5LVK5 PTHR19134:SF542 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;synaptic membrane adhesion#GO:0099560;cell communication#GO:0007154;cell adhesion#GO:0007155;synapse organization#GO:0050808;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000000873.1|UniProtKB=W5LXW3 W5LXW3 PTHR24232:SF85 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005331.1|UniProtKB=W5MDG4 W5MDG4 PTHR46242:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 ZCCHC9 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000016050.1|UniProtKB=W5NGL2 W5NGL2 PTHR22957:SF255 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 22A GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000001363.1|UniProtKB=W5LZI5 W5LZI5 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017323.1|UniProtKB=W5NLB9 W5NLB9 PTHR22923:SF121 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 4 regulation of cytokine-mediated signaling pathway#GO:0001959;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;regulation of response to cytokine stimulus#GO:0060759;positive regulation of cytokine-mediated signaling pathway#GO:0001961;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of non-canonical NF-kappaB signal transduction#GO:1901222 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008184.1|UniProtKB=W5MNH7 W5MNH7 PTHR13439:SF49 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 4-B homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;chemical homeostasis#GO:0048878 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017972.1|UniProtKB=W5NN64 W5NN64 PTHR11711:SF427 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 14 ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014252.1|UniProtKB=W5NAA0 W5NAA0 PTHR10166:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-2 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803 calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005417.1|UniProtKB=W5MDS9 W5MDS9 PTHR11700:SF8 30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US10 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000004418.1|UniProtKB=W5MA74 W5MA74 PTHR15351:SF2 ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG ERLIN-1 alcohol binding#GO:0043178;lipid binding#GO:0008289;cholesterol binding#GO:0015485;steroid binding#GO:0005496;small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;SREBP signaling pathway#GO:0032933;biological regulation#GO:0065007;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896;signaling#GO:0023052 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 LEPOC|Ensembl=ENSLOCG00000002177.1|UniProtKB=W5M2E8 W5M2E8 PTHR11203:SF37 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER INTEGRATOR COMPLEX SUBUNIT 11 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000005270.1|UniProtKB=W5MDC8 W5MDC8 PTHR23113:SF187 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000008530.1|UniProtKB=W5MPS5 W5MPS5 PTHR43109:SF2 NUCLEOSIDE DIPHOSPHATE KINASE 7 NUCLEOSIDE DIPHOSPHATE KINASE 7 cytoplasmic microtubule#GO:0005881;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 transferase#PC00220;kinase#PC00137 De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907 LEPOC|Ensembl=ENSLOCG00000013914.1|UniProtKB=W5N944 W5N944 PTHR14465:SF0 IQ DOMAIN-CONTAINING PROTEIN H IQ DOMAIN-CONTAINING PROTEIN H LEPOC|Ensembl=ENSLOCG00000009356.1|UniProtKB=W5MSQ4 W5MSQ4 PTHR23277:SF12 NECTIN-RELATED NECTIN-3 protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical junction complex#GO:0043296;cell junction#GO:0030054;adherens junction#GO:0005912;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000003408.1|UniProtKB=W5M6M5 W5M6M5 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000010072.1|UniProtKB=W5MVB0 W5MVB0 PTHR46169:SF17 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004036.1|UniProtKB=W5M8Y7 W5M8Y7 PTHR43377:SF2 BILIVERDIN REDUCTASE A BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00560)-RELATED dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000011078.1|UniProtKB=W5MZ16 W5MZ16 PTHR24416:SF47 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714 cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;myeloid cell differentiation#GO:0030099;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;leukocyte differentiation#GO:0002521;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell migration#GO:0016477;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;hemopoiesis#GO:0030097;biological regulation#GO:0065007;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;osteoclast differentiation#GO:0030316;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016870.1|UniProtKB=W5NJP5 W5NJP5 PTHR11829:SF167 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-BETA RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007283.1|UniProtKB=W5MKB2 W5MKB2 PTHR23233:SF51 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 1 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008323.1|UniProtKB=W5MP05 W5MP05 PTHR12845:SF2 GUANINE NUCLEOTIDE EXCHANGE FACTOR DH DOMAIN-CONTAINING PROTEIN-RELATED guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 regulation of actin filament-based process#GO:0032970;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000009821.1|UniProtKB=W5MUE3 W5MUE3 PTHR16089:SF11 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006753.1|UniProtKB=W5MIF5 W5MIF5 PTHR24253:SF163 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 4A ISOFORM X1-RELATED peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013661.1|UniProtKB=W5N883 W5N883 PTHR24203:SF14 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 10 LEPOC|Ensembl=ENSLOCG00000001939.1|UniProtKB=W5M1J3 W5M1J3 PTHR10802:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40B transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013938.1|UniProtKB=W5N974 W5N974 PTHR10797:SF79 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;CCR4-NOT complex#GO:0030014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000004234.1|UniProtKB=W5M9K6 W5M9K6 PTHR11011:SF119 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579 LEPOC|Ensembl=ENSLOCG00000016577.1|UniProtKB=W5NIM1 W5NIM1 KMO PTHR46028:SF2 KYNURENINE 3-MONOOXYGENASE KYNURENINE 3-MONOOXYGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001735.1|UniProtKB=W5M0U6 W5M0U6 PTHR11214:SF234 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;biosynthetic process#GO:0009058;aminoglycan biosynthetic process#GO:0006023;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000000290.1|UniProtKB=W5LW25 W5LW25 PTHR11984:SF1 CONNEXIN GAP JUNCTION EPSILON-1 PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 cell junction#GO:0030054;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000005380.1|UniProtKB=W5MDM5 W5MDM5 PTHR12642:SF0 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000017094.1|UniProtKB=W5NKG4 W5NKG4 PTHR11732:SF294 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009996.1|UniProtKB=W5MV13 W5MV13 PTHR12454:SF5 TRIMERIC INTRACELLULAR CATION CHANNEL TRIMERIC INTRACELLULAR CATION CHANNEL TYPE B potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017;cytoplasm#GO:0005737;membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000012695.1|UniProtKB=W5N4R1 W5N4R1 PTHR13023:SF3 APYRASE SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE 1 pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110 biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 membrane#GO:0016020;cellular anatomical structure#GO:0110165 nucleotide phosphatase#PC00173;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014167.1|UniProtKB=W5N9Z3 W5N9Z3 PTHR24240:SF65 OPSIN NOVEL OPSIN-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to radiation#GO:0071478;signaling#GO:0023052;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signal transduction#GO:0007165;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214 photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011281.1|UniProtKB=W5MZQ5 W5MZQ5 PTHR43015:SF1 D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000013119.1|UniProtKB=W5N698 W5N698 PTHR19353:SF13 FATTY ACID DESATURASE 2 FATTY ACID DESATURASE 6 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008187.1|UniProtKB=W5MNI1 W5MNI1 PTHR18945:SF29 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT BETA channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;ligand-gated channel activity#GO:0022834;chloride channel activity#GO:0005254 monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;organelle#GO:0043226;synaptic membrane#GO:0097060;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;cell junction#GO:0030054 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000011282.1|UniProtKB=W5MZR6 W5MZR6 PTHR17204:SF5 PRE-MRNA PROCESSING PROTEIN PRP39-RELATED PRE-MRNA-PROCESSING FACTOR 39 RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;nucleic acid binding#GO:0003676 gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;ribonucleoprotein complex biogenesis#GO:0022613;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015954.1|UniProtKB=W5NG86 W5NG86 PTHR46787:SF1 SYNDROMES PUTATIVE CHAPERONIN-RELATED MOLECULAR CHAPERONE MKKS organelle assembly#GO:0070925;chaperone-mediated protein complex assembly#GO:0051131;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cilium#GO:0005929;intracellular organelle#GO:0043229;cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000006838.1|UniProtKB=W5MIU0 W5MIU0 PTHR22754:SF38 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG B ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 regulation of nervous system development#GO:0051960;regulation of cell size#GO:0008361;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;cellular component organization#GO:0016043;negative regulation of cellular component organization#GO:0051129;regulation of neurogenesis#GO:0050767;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of axonogenesis#GO:0050770;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of anatomical structure size#GO:0090066;regulation of cell differentiation#GO:0045595;regulation of cell growth#GO:0001558;regulation of multicellular organismal process#GO:0051239;negative regulation of cell growth#GO:0030308;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of cell development#GO:0060284;regulation of neuron projection development#GO:0010975 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000007551.1|UniProtKB=W5ML98 W5ML98 PTHR33524:SF2 C5ORF35 SET DOMAIN-CONTAINING PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000016792.1|UniProtKB=W5NJE6 W5NJE6 PTHR10157:SF41 DOPAMINE BETA HYDROXYLASE RELATED DBH-LIKE MONOOXYGENASE PROTEIN 2 HOMOLOG oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;extracellular region#GO:0005576;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 hydroxylase#PC00122 LEPOC|Ensembl=ENSLOCG00000013004.1|UniProtKB=W5N5V5 W5N5V5 PTHR41693:SF2 HEME-BINDING PROTEIN 1 SI:DKEY-282H22.5 LEPOC|Ensembl=ENSLOCG00000016558.1|UniProtKB=W5NIJ4 W5NIJ4 PTHR20856:SF5 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA2 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 LEPOC|Ensembl=ENSLOCG00000013105.1|UniProtKB=W5N684 W5N684 PTHR12271:SF127 POLY A POLYMERASE CID PAP -RELATED SPECKLE TARGETED PIP5K1A-REGULATED POLY(A) POLYMERASE catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;positive regulation of macromolecule metabolic process#GO:0010604;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;membraneless organelle#GO:0043228;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000013709.1|UniProtKB=W5N8E6 W5N8E6 CFAP100 PTHR21683:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED CILIA AND FLAGELLA ASSOCIATED PROTEIN 100 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005582.1|UniProtKB=W5MEC8 W5MEC8 PTHR45857:SF5 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular process#GO:0009987;cell motility#GO:0048870;cell migration#GO:0016477 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000008365.1|UniProtKB=W5MP52 W5MP52 PTHR10529:SF373 AP COMPLEX SUBUNIT MU AP-2 COMPLEX SUBUNIT MU cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 post-Golgi vesicle-mediated transport#GO:0006892;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;clathrin-dependent endocytosis#GO:0072583;postsynaptic neurotransmitter receptor internalization#GO:0098884;endocytosis#GO:0006897;vacuolar transport#GO:0007034;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;receptor internalization#GO:0031623;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192 clathrin vesicle coat#GO:0030125;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;cell junction#GO:0030054;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;vesicle coat#GO:0030120;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;endocytic vesicle#GO:0030139;coated membrane#GO:0048475;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;synapse#GO:0045202;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytosol#GO:0005829;vesicle membrane#GO:0012506;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;synaptic vesicle#GO:0008021;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 CCKR signaling map#P06959>AP2M1#P07067 LEPOC|Ensembl=ENSLOCG00000017599.1|UniProtKB=W5NM45 W5NM45 PTHR11214:SF91 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 9 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;biosynthetic process#GO:0009058;aminoglycan biosynthetic process#GO:0006023;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000004751.1|UniProtKB=W5MBD9 W5MBD9 PTHR15672:SF14 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN CAMP-REGULATED PHOSPHOPROTEIN 21 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006059.1|UniProtKB=W5MG14 W5MG14 PTHR11680:SF28 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363 amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 LEPOC|Ensembl=ENSLOCG00000015019.1|UniProtKB=W5NCY1 W5NCY1 PTHR11245:SF1 STANNIOCALCIN STANNIOCALCIN-1 intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000009688.1|UniProtKB=W5MTY3 W5MTY3 PTHR10745:SF0 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 GLYCINE--TRNA LIGASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011416.1|UniProtKB=W5N074 W5N074 PTHR10250:SF4 MICROSOMAL GLUTATHIONE S-TRANSFERASE LEUKOTRIENE C4 SYNTHASE oxidoreductase activity#GO:0016491;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;transferase activity#GO:0016740;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846;glutathione transferase activity#GO:0004364 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967 transferase#PC00220 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 LEPOC|Ensembl=ENSLOCG00000000267.1|UniProtKB=W5LVZ4 W5LVZ4 PTHR10459:SF118 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 2 glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 LEPOC|Ensembl=ENSLOCG00000002779.1|UniProtKB=W5M4G8 W5M4G8 PTHR10826:SF1 COMPLEMENT COMPONENT 1 COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-RNA adaptor activity#GO:0140517 macromolecule metabolic process#GO:0043170;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 complement component#PC00078;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000308.1|UniProtKB=W5LW28 W5LW28 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010976.1|UniProtKB=W5MYK2 W5MYK2 PTHR31345:SF3 CENTROMERE PROTEIN Q CENTROMERE PROTEIN Q chromosome localization#GO:0050000;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;cellular process#GO:0009987;cell cycle process#GO:0022402;localization#GO:0051179;metaphase chromosome alignment#GO:0051310;organelle localization#GO:0051640;chromosome segregation#GO:0007059 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007850.1|UniProtKB=W5MMC2 W5MMC2 PTHR46545:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51 intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;axoneme#GO:0005930 LEPOC|Ensembl=ENSLOCG00000004711.1|UniProtKB=W5MB86 W5MB86 PTHR24404:SF46 ZINC FINGER PROTEIN ZINC FINGER PROTEIN GFI-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008981.1|UniProtKB=W5MRD8 W5MRD8 PTHR21437:SF2 WIDE AWAKE ANKYRIN REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 1-LIKE regulation of cellular process#GO:0050794;establishment of organelle localization#GO:0051656;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell cycle process#GO:0022402;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;spindle localization#GO:0051653;cellular localization#GO:0051641;localization#GO:0051179;organelle localization#GO:0051640;establishment or maintenance of cell polarity#GO:0007163;regulation of establishment or maintenance of cell polarity#GO:0032878;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;mitotic cell cycle process#GO:1903047 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000017802.1|UniProtKB=W5NMP7 W5NMP7 PTHR13563:SF5 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG C tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013103.1|UniProtKB=W5N681 W5N681 PTHR31328:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 localization#GO:0051179;cellular localization#GO:0051641;organelle localization#GO:0051640;pigmentation#GO:0043473;establishment of organelle localization#GO:0051656;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;establishment of vesicle localization#GO:0051650;cellular pigmentation#GO:0033059;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987 cell-cell contact zone#GO:0044291;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;neuromuscular junction#GO:0031594;cell junction#GO:0030054;cytoskeleton#GO:0005856;stress fiber#GO:0001725;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133;actomyosin#GO:0042641;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;BLOC-1 complex#GO:0031083;membrane-bounded organelle#GO:0043227;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000002974.1|UniProtKB=W5M573 W5M573 PTHR12726:SF0 CERAMIDE GLUCOSYLTRANSFERASE CERAMIDE GLUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;glycolipid biosynthetic process#GO:0009247;glycosphingolipid biosynthetic process#GO:0006688 membrane#GO:0016020;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000000123.1|UniProtKB=W5LVH9 W5LVH9 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED binding#GO:0005488;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010872.1|UniProtKB=W5MY60 W5MY60 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017789.1|UniProtKB=W5NMN4 W5NMN4 PTHR11984:SF13 CONNEXIN GAP JUNCTION ALPHA-5 PROTEIN channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;animal gross anatomical part developmental process#GO:0160108;regulation of heart contraction#GO:0008016;signaling#GO:0023052;circulatory system development#GO:0072359;regulation of biological process#GO:0050789;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of system process#GO:0044057;regulation of multicellular organismal process#GO:0051239;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular process#GO:0009987 anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000015496.1|UniProtKB=W5NEL3 W5NEL3 PTHR24055:SF146 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 12 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;p38 MAPK pathway#P05918>p38gamma#P06015;Ras Pathway#P04393>p38#P04558;Oxidative stress response#P00046>p38#P01135;B cell activation#P00010>p38#P00384;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;EGF receptor signaling pathway#P00018>p38#P00562;TGF-beta signaling pathway#P00052>P38#P01275;Parkinson disease#P00049>SAPK#P01219;FGF signaling pathway#P00021>p38#P00644;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831 LEPOC|Ensembl=ENSLOCG00000010912.1|UniProtKB=W5MYB9 W5MYB9 PTHR13713:SF60 SIALYLTRANSFERASE LACTOSYLCERAMIDE ALPHA-2,3-SIALYLTRANSFERASE sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017990.1|UniProtKB=W5NN82 W5NN82 PTHR24246:SF21 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE A2C RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005882.1|UniProtKB=W5MFE5 W5MFE5 PTHR43986:SF1 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000003551.1|UniProtKB=W5M736 W5M736 PTHR24206:SF95 OS06G0237300 PROTEIN CYTOSKELETON-ASSOCIATED LIM DOMAIN PROTEIN-RELATED cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000016185.1|UniProtKB=W5NH42 W5NH42 PTHR23197:SF8 TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 skeletal muscle tissue development#GO:0007519;tissue development#GO:0009888;muscle structure development#GO:0061061;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;muscle organ development#GO:0007517;muscle tissue development#GO:0060537;animal organ development#GO:0048513;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000004360.1|UniProtKB=W5MA00 W5MA00 PTHR21590:SF3 SEA DOMAIN-CONTAINING PROTEIN UPF0606 PROTEIN KIAA1549L LEPOC|Ensembl=ENSLOCG00000010491.1|UniProtKB=W5MWU9 W5MWU9 PTHR14499:SF28 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD16 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of biological process#GO:0050789;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731 postsynapse#GO:0098794;presynaptic active zone membrane#GO:0048787;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic membrane#GO:0045211;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cell junction#GO:0030054;presynaptic active zone#GO:0048786 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003232.1|UniProtKB=W5M609 W5M609 PTHR12876:SF10 N4BP1-RELATED ENDORIBONUCLEASE ZC3H12A catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;nuclease activity#GO:0004518;RNA binding#GO:0003723 positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000016999.1|UniProtKB=W5NK56 W5NK56 PTHR24070:SF17 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAB-42 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GTP#P01280;Integrin signalling pathway#P00034>Ras#P00916;Ras Pathway#P04393>Ras#P04547;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;EGF receptor signaling pathway#P00018>Ras#P00552;PDGF signaling pathway#P00047>Ras#P01154;p53 pathway feedback loops 2#P04398>Ras#P04651;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;FGF signaling pathway#P00021>Ras#P00633;PI3 kinase pathway#P00048>Ras#P01182 LEPOC|Ensembl=ENSLOCG00000002864.1|UniProtKB=W5M4S1 W5M4S1 PTHR19957:SF334 SYNTAXIN SYNTAXIN-1B SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;vesicle fusion#GO:0006906;export from cell#GO:0140352;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;secretion by cell#GO:0032940;protein transport#GO:0015031;macromolecule localization#GO:0033036;organelle organization#GO:0006996;membrane fusion#GO:0061025;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;exocytosis#GO:0006887;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050 cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;endomembrane system#GO:0012505;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 LEPOC|Ensembl=ENSLOCG00000015922.1|UniProtKB=W5NG46 W5NG46 PTHR21663:SF2 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5B vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000000956.1|UniProtKB=W5LY71 W5LY71 PTHR24221:SF664 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane#GO:0016020;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000007235.1|UniProtKB=W5MK48 W5MK48 PTHR12391:SF0 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010 Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Integrin signalling pathway#P00034>Arp2/3#P00912;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 LEPOC|Ensembl=ENSLOCG00000011853.1|UniProtKB=W5N1R6 W5N1R6 PTHR10903:SF206 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017288.1|UniProtKB=W5NL77 W5NL77 PTHR24249:SF415 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000018215.1|UniProtKB=W5NNV7 W5NNV7 PTHR26451:SF991 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005099.1|UniProtKB=W5MCP0 W5MCP0 PTHR11049:SF24 ACYL COENZYME A THIOESTER HYDROLASE CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000007302.1|UniProtKB=W5MKE1 W5MKE1 PTHR14093:SF19 HLA CLASS II GAMMA CHAIN THYROGLOBULIN biological regulation#GO:0065007;hormone metabolic process#GO:0042445;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;modified amino acid metabolic process#GO:0006575;regulation of biological quality#GO:0065008;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007119.1|UniProtKB=W5MJR1 W5MJR1 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN LEPOC|Ensembl=ENSLOCG00000017203.1|UniProtKB=W5NKV7 W5NKV7 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000016360.1|UniProtKB=W5NHV2 W5NHV2 PTHR10724:SF10 30S RIBOSOMAL PROTEIN S1 S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000011437.1|UniProtKB=W5N0A0 W5N0A0 PTHR11073:SF11 CALRETICULIN AND CALNEXIN CALNEXIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 response to chemical#GO:0042221;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008769.1|UniProtKB=W5MQL8 W5MQL8 PTHR46464:SF1 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN AND ARMADILLO REPEAT-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016200.1|UniProtKB=W5NH66 W5NH66 PTHR12352:SF21 SECRETED MODULAR CALCIUM-BINDING PROTEIN SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 2 extracellular matrix binding#GO:0050840;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;heparin binding#GO:0008201 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000014761.1|UniProtKB=W5NC23 W5NC23 PTHR21229:SF52 LUNG SEVEN TRANSMEMBRANE RECEPTOR TRANSMEMBRANE PROTEIN 87A-LIKE ISOFORM X1 intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012150.1|UniProtKB=W5N2T7 W5N2T7 PTHR24403:SF63 ZINC FINGER PROTEIN SI:DKEY-154P10.3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000013848.1|UniProtKB=W5N8X0 W5N8X0 PTHR47577:SF1 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN-CONTAINING PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000003180.1|UniProtKB=W5M5V0 W5M5V0 PTHR17573:SF0 UROPLAKIN II UROPLAKIN-2 cellular process#GO:0009987;epithelium development#GO:0060429;cell differentiation#GO:0030154;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000002599.1|UniProtKB=W5M3U8 W5M3U8 PTHR10762:SF2 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2 cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 LEPOC|Ensembl=ENSLOCG00000015207.1|UniProtKB=W5NDK3 W5NDK3 PTHR28358:SF1 TRANSMEMBRANE PROTEIN 127 TRANSMEMBRANE PROTEIN 127 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of TOR signaling#GO:0032006;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000017026.1|UniProtKB=W5NK85 W5NK85 PTHR19957:SF90 SYNTAXIN SYNTAXIN-7 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;vesicle fusion#GO:0006906 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503 SNARE protein#PC00034 Parkinson disease#P00049>Syntaxin#P01215;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 LEPOC|Ensembl=ENSLOCG00000015385.1|UniProtKB=W5NE73 W5NE73 PTHR43128:SF2 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE B CHAIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000004189.1|UniProtKB=W5M9E3 W5M9E3 PTHR45636:SF17 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-3 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009260.1|UniProtKB=W5MSD5 W5MSD5 PTHR15951:SF2 T-CELL RECEPTOR-ASSOCIATED TRANSMEMBRANE ADAPTER 1 T-CELL RECEPTOR-ASSOCIATED TRANSMEMBRANE ADAPTER 1 negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;positive regulation of immune system process#GO:0002684;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 signaling receptor complex#GO:0043235;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005644.1|UniProtKB=W5MEL9 W5MEL9 PTHR10822:SF19 GLYPICAN GLYPICAN 2 positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of biological process#GO:0048518;regulation of protein localization to membrane#GO:1905475;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of localization#GO:0032879;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of protein localization#GO:0032880;regulation of signaling#GO:0023051 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017577.1|UniProtKB=W5NM23 W5NM23 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005332.1|UniProtKB=W5MDG6 W5MDG6 PTHR45904:SF1 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG B RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000001285.1|UniProtKB=W5LZ96 W5LZ96 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;immune response#GO:0006955;signal transduction#GO:0007165;cell communication#GO:0007154;immune system process#GO:0002376 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013037.1|UniProtKB=W5N608 W5N608 PTHR24240:SF15 OPSIN RHODOPSIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;detection of stimulus#GO:0051606;signal transduction#GO:0007165;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;signaling#GO:0023052;cellular response to radiation#GO:0071478 non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin#P00747 LEPOC|Ensembl=ENSLOCG00000012305.1|UniProtKB=W5N3D0 W5N3D0 PTHR46144:SF8 ZINC FINGER PROTEIN 385B-LIKE ZINC FINGER PROTEIN 346 LEPOC|Ensembl=ENSLOCG00000009690.1|UniProtKB=W5MTX5 W5MTX5 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000005568.1|UniProtKB=W5MEB7 W5MEB7 PTHR23288:SF9 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;snRNA transcription#GO:0009301;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;regulation of DNA-templated transcription elongation#GO:0032784;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;positive regulation of biosynthetic process#GO:0009891;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000008934.1|UniProtKB=W5MR80 W5MR80 PTHR19328:SF27 HEDGEHOG-INTERACTING PROTEIN HEDGEHOG-INTERACTING PROTEIN protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000000131.1|UniProtKB=W5LVI5 W5LVI5 PTHR14241:SF1 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 LEPOC|Ensembl=ENSLOCG00000003286.1|UniProtKB=W5M673 W5M673 PTHR45787:SF2 LD11652P RHOMBOTIN-1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000012543.1|UniProtKB=W5N490 W5N490 PTHR11006:SF49 PROTEIN ARGININE N-METHYLTRANSFERASE HISTONE-ARGININE METHYLTRANSFERASE CARM1 ISOFORM X1 protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993 chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007296.1|UniProtKB=W5MKC5 W5MKC5 PTHR10845:SF155 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 18 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 negative regulation of cell communication#GO:0010648;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744 cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 GTPase-activating protein#PC00257 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000004571.1|UniProtKB=W5MAR8 W5MAR8 PTHR43294:SF15 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;export from cell#GO:0140352;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;transmembrane transport#GO:0055085;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000004628.1|UniProtKB=W5MAY9 W5MAY9 PTHR18875:SF8 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO COILED-COIL DOMAIN-CONTAINING PROTEIN 18 intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;centriolar satellite#GO:0034451;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010519.1|UniProtKB=W5MWX9 W5MWX9 PTHR46820:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD7 HISTONE-LYSINE N-METHYLTRANSFERASE SETD7 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;heterochromatin organization#GO:0070828;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000004170.1|UniProtKB=W5M9C4 W5M9C4 PTHR12730:SF0 HSDA/SDA1-RELATED PROTEIN SDA1 HOMOLOG establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;ribosomal large subunit export from nucleus#GO:0000055;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal large subunit biogenesis#GO:0042273;organelle localization#GO:0051640;ribosome biogenesis#GO:0042254;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000014079.1|UniProtKB=W5N9P0 W5N9P0 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013876.1|UniProtKB=W5N901 W5N901 PTHR16275:SF9 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 establishment of localization#GO:0051234;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regionalization#GO:0003002;epithelium development#GO:0060429;tube development#GO:0035295;plasma membrane bounded cell projection organization#GO:0120036;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;localization#GO:0051179;axoneme assembly#GO:0035082;system development#GO:0048731;organelle assembly#GO:0070925;embryonic organ development#GO:0048568;microtubule bundle formation#GO:0001578;pattern specification process#GO:0007389;microtubule-based movement#GO:0007018;animal organ morphogenesis#GO:0009887;tube morphogenesis#GO:0035239;determination of left/right symmetry#GO:0007368;heart morphogenesis#GO:0003007;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;morphogenesis of an epithelium#GO:0002009;microtubule-based process#GO:0007017;left/right pattern formation#GO:0060972;heart development#GO:0007507;cellular component assembly#GO:0022607;determination of bilateral symmetry#GO:0009855;embryo development#GO:0009790;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium organization#GO:0044782;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;cilium movement#GO:0003341;cell projection organization#GO:0030030;circulatory system development#GO:0072359;cilium assembly#GO:0060271;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000001829.1|UniProtKB=W5M165 W5M165 PTHR10507:SF0 CDC45-RELATED PROTEIN CELL DIVISION CONTROL PROTEIN 45 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;DNA replication origin binding#GO:0003688;single-stranded DNA binding#GO:0003697;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 recombinational repair#GO:0000725;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitotic cell cycle#GO:0000278;DNA damage response#GO:0006974;DNA repair#GO:0006281;cell cycle DNA replication#GO:0044786;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;double-strand break repair via break-induced replication#GO:0000727;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;cellular component organization#GO:0016043;response to stimulus#GO:0050896;DNA recombination#GO:0006310;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;protein-containing complex organization#GO:0043933;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607 nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;DNA replication preinitiation complex#GO:0031261;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231 replication origin binding protein#PC00199;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000016540.1|UniProtKB=W5NIG8 W5NIG8 PTHR11254:SF363 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HACE1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;Golgi organization#GO:0007030;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005039.1|UniProtKB=W5MCF8 W5MCF8 PTHR23010:SF1 MIDNOLIN MIDNOLIN cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008832.1|UniProtKB=W5MQT9 W5MQT9 PTHR18640:SF5 SOLUTE CARRIER FAMILY 10 MEMBER 7 SODIUM_BILE ACID COTRANSPORTER 7 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000015347.1|UniProtKB=W5NE28 W5NE28 PTHR45789:SF3 FI18025P1 TRANSCRIPTION FACTOR SOX-5 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001230.1|UniProtKB=W5LZ58 W5LZ58 PTHR23192:SF37 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 2B cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006977.1|UniProtKB=W5MJ85 W5MJ85 PTHR11679:SF27 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 2 SNARE binding#GO:0000149;binding#GO:0005488;syntaxin binding#GO:0019905;protein binding#GO:0005515 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;regulation of biological process#GO:0050789;export from cell#GO:0140352;signaling#GO:0023052;establishment of organelle localization#GO:0051656;secretion by cell#GO:0032940;protein transport#GO:0015031;cellular localization#GO:0051641;vesicle localization#GO:0051648;macromolecule localization#GO:0033036;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;intracellular transport#GO:0046907;calcium-ion regulated exocytosis#GO:0017156;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903 membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000005316.1|UniProtKB=W5MDE3 W5MDE3 PTHR43908:SF8 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY B MEMBER 12 heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;cellular response to misfolded protein#GO:0071218;macromolecule metabolic process#GO:0043170;response to misfolded protein#GO:0051788;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000015803.1|UniProtKB=W5NFP8 W5NFP8 PTHR11908:SF80 XANTHINE DEHYDROGENASE XANTHINE DEHYDROGENASE_OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;purine-containing compound catabolic process#GO:0072523;purine nucleobase catabolic process#GO:0006145;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;primary metabolic process#GO:0044238;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Purine metabolism#P02769>Xanthine Oxidase#P03116;Adenine and hypoxanthine salvage pathway#P02723>Xanthine dehydrogenase#P02809 LEPOC|Ensembl=ENSLOCG00000005313.1|UniProtKB=W5MDG5 W5MDG5 PTHR22692:SF24 MYOSIN VII, XV MYOSIN VIIB actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000000759.1|UniProtKB=W5LXI7 W5LXI7 PTHR22572:SF104 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE REGULATORY SUBUNIT ALPHA catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 LEPOC|Ensembl=ENSLOCG00000001028.1|UniProtKB=W5LYE4 W5LYE4 PTHR34033:SF1 AP-5 COMPLEX SUBUNIT BETA-1 AP-5 COMPLEX SUBUNIT BETA-1 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119 LEPOC|Ensembl=ENSLOCG00000003511.1|UniProtKB=W5M6Z5 W5M6Z5 PTHR31131:SF3 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 1 amino acid binding#GO:0016597;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;organic acid binding#GO:0043177 cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of TORC1 signaling#GO:1904262;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;response to nitrogen compound#GO:1901698;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000012107.1|UniProtKB=W5N2N4 W5N2N4 PTHR21472:SF18 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000011809.1|UniProtKB=W5N1L3 W5N1L3 PTHR34038:SF1 ATP SYNTHASE MEMBRANE SUBUNIT DAPIT, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT K, MITOCHONDRIAL membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;catalytic complex#GO:1902494;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000005508.1|UniProtKB=W5ME36 W5ME36 PTHR11920:SF497 GUANYLYL CYCLASE GUANYLATE CYCLASE molecular transducer activity#GO:0060089;lyase activity#GO:0016829;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;peptide receptor activity#GO:0001653;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023 carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;cell communication#GO:0007154;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanylate cyclase#PC00114;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000010731.1|UniProtKB=W5MXP3 W5MXP3 PTHR24092:SF79 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VB intramembrane lipid carrier activity#GO:0140303;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;macromolecule localization#GO:0033036;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008358.1|UniProtKB=W5MP61 W5MP61 PTHR19143:SF338 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN GAMMA CHAIN hemostasis#GO:0007599;primary metabolic process#GO:0044238;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;blood coagulation, fibrin clot formation#GO:0072378;cell activation#GO:0001775;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;protein metabolic process#GO:0019538;cell-substrate adhesion#GO:0031589;protein activation cascade#GO:0072376;regulation of biological quality#GO:0065008;wound healing#GO:0042060;cell-cell adhesion#GO:0098609;response to wounding#GO:0009611;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;coagulation#GO:0050817;protein maturation#GO:0051604;gene expression#GO:0010467;multicellular organismal process#GO:0032501;homotypic cell-cell adhesion#GO:0034109;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;platelet aggregation#GO:0070527;macromolecule metabolic process#GO:0043170;platelet activation#GO:0030168;blood coagulation#GO:0007596 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443;Blood coagulation#P00011>Fibrinogen#P00406;Blood coagulation#P00011>Fibrin monomer#P00418 LEPOC|Ensembl=ENSLOCG00000010257.1|UniProtKB=W5MW10 W5MW10 PTHR15036:SF40 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 4 developmental process#GO:0032502;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000016886.1|UniProtKB=W5NJR8 W5NJR8 PTHR12369:SF15 CHONDROITIN SYNTHASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE 3 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000007189.1|UniProtKB=W5MJZ9 W5MJZ9 PTHR13859:SF12 ATROPHIN-RELATED ARGININE-GLUTAMIC ACID DIPEPTIDE REPEATS PROTEIN transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000012659.1|UniProtKB=W5N4L9 W5N4L9 PTHR44427:SF5 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000593.1|UniProtKB=W5LX17 W5LX17 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011365.1|UniProtKB=W5N015 W5N015 PTHR10627:SF59 SCP160 BICAUDAL C HOMOLOG 2 ISOFORM X2 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009716.1|UniProtKB=W5MU09 W5MU09 PTHR28004:SF2 ZGC:162816-RELATED D-SERINE DEHYDRATASE lyase activity#GO:0016829;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 LEPOC|Ensembl=ENSLOCG00000017465.1|UniProtKB=W5NLR1 W5NLR1 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012399.1|UniProtKB=W5N3R7 W5N3R7 PTHR16199:SF4 CONDENSIN-2 COMPLEX SUBUNIT G2 CONDENSIN-2 COMPLEX SUBUNIT G2 organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;nuclear division#GO:0000280 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;condensin complex#GO:0000796;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000008057.1|UniProtKB=W5MN37 W5MN37 PTHR10972:SF194 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 2 steroid binding#GO:0005496;cholesterol binding#GO:0015485;lipid binding#GO:0008289;alcohol binding#GO:0043178;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000017062.1|UniProtKB=W5NKE2 W5NKE2 PTHR24023:SF938 COLLAGEN ALPHA COLLAGEN ALPHA-1(XIX) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000000545.1|UniProtKB=W5LWY3 W5LWY3 PTHR11003:SF21 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 2 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000003901.1|UniProtKB=W5M8E7 W5M8E7 PTHR23419:SF2 DIVALENT CATION TOLERANCE CUTA-RELATED CUTA DIVALENT CATION TOLERANCE HOMOLOG-LIKE transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;copper ion binding#GO:0005507;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000017778.1|UniProtKB=W5NMM3 W5NMM3 PTHR45773:SF7 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 1 plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;neurogenesis#GO:0022008;positive regulation of synapse assembly#GO:0051965;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell junction assembly#GO:1901888;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;positive regulation of cellular component biogenesis#GO:0044089;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;regulation of synapse organization#GO:0050807;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;GABA-ergic synapse#GO:0098982;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;membrane#GO:0016020;cell periphery#GO:0071944;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008293.1|UniProtKB=W5MNW8 W5MNW8 PTHR12659:SF6 RHO-TYPE GTPASE ACTIVATING PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 13 enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of signaling#GO:0023051;actin filament-based process#GO:0030029;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cell communication#GO:0010646;actin cytoskeleton organization#GO:0030036;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000005229.1|UniProtKB=W5MD37 W5MD37 PTHR21004:SF0 SERINE PROTEASE-RELATED PEROXISOMAL LEADER PEPTIDE-PROCESSING PROTEASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;regulation of lipid catabolic process#GO:0050994;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;proteolysis#GO:0006508;regulation of lipid metabolic process#GO:0019216;protein metabolic process#GO:0019538;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000011946.1|UniProtKB=W5N240 W5N240 PTHR11177:SF406 CHITINASE ACIDIC MAMMALIAN CHITINASE-RELATED hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009893.1|UniProtKB=W5MUN4 W5MUN4 PTHR14699:SF2 STI2 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 21A intracellular protein localization#GO:0008104;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;spermatogenesis#GO:0007283;intracellular transport#GO:0046907;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;male gamete generation#GO:0048232;macromolecule localization#GO:0033036;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;localization#GO:0051179;spermatid development#GO:0007286;sexual reproduction#GO:0019953;reproductive process#GO:0022414;intraciliary transport#GO:0042073;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;microtubule-based movement#GO:0007018;cell motility#GO:0048870;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular localization#GO:0051641;cilium-dependent cell motility#GO:0060285;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;microtubule-based transport#GO:0099111;spermatid differentiation#GO:0048515;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;intraciliary retrograde transport#GO:0035721;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;sperm motility#GO:0097722;cellular component organization#GO:0016043 intraciliary transport particle#GO:0030990;intraciliary transport particle A#GO:0030991;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000001875.1|UniProtKB=W5M1C6 W5M1C6 PTHR24342:SF18 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000010256.1|UniProtKB=W5MVZ3 W5MVZ3 PTHR24056:SF159 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 15 protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;cyclin binding#GO:0030332;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 protein kinase complex#GO:1902911;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013326.1|UniProtKB=W5N715 W5N715 PTHR11205:SF19 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7M structural molecule activity#GO:0005198;RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 intracellular organelle#GO:0043229;ribosome#GO:0005840;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000011902.1|UniProtKB=W5N1X7 W5N1X7 PTHR47222:SF3 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 532 LEPOC|Ensembl=ENSLOCG00000002804.1|UniProtKB=W5M4K0 W5M4K0 PTHR31742:SF1 RPA-INTERACTING PROTEIN RPAIN RPA-INTERACTING PROTEIN macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000005188.1|UniProtKB=W5MD28 W5MD28 PTHR13743:SF123 BEIGE/BEACH-RELATED PROTEIN FAN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002367.1|UniProtKB=W5M317 W5M317 PTHR28605:SF1 CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE) CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;positive regulation of DNA metabolic process#GO:0051054;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000005730.1|UniProtKB=W5MEW6 W5MEW6 PTHR24254:SF10 PROTHROMBIN PROTHROMBIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 platelet activation#GO:0030168;blood coagulation#GO:0007596;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;multicellular organismal process#GO:0032501;regulation of response to external stimulus#GO:0032101;positive regulation of response to stimulus#GO:0048584;regulation of coagulation#GO:0050818;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;response to stress#GO:0006950;response to wounding#GO:0009611;regulation of response to wounding#GO:1903034;regulation of hemostasis#GO:1900046;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;coagulation#GO:0050817;wound healing#GO:0042060;regulation of biological quality#GO:0065008;positive regulation of coagulation#GO:0050820;cell activation#GO:0001775;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;response to stimulus#GO:0050896;regulation of wound healing#GO:0061041;hemostasis#GO:0007599;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 Blood coagulation#P00011>Prothrombin#P00416;Blood coagulation#P00011>Thrombin#P00414 LEPOC|Ensembl=ENSLOCG00000017989.1|UniProtKB=W5NN81 W5NN81 PTHR21426:SF12 EXOCYST COMPLEX COMPONENT 8 EXOCYST COMPLEX COMPONENT 8 vesicle-mediated transport#GO:0016192;Golgi to plasma membrane transport#GO:0006893;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;post-Golgi vesicle-mediated transport#GO:0006892;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization within membrane#GO:0051668 cell periphery#GO:0071944;cell cortex#GO:0005938;cytoplasm#GO:0005737;exocyst#GO:0000145;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 LEPOC|Ensembl=ENSLOCG00000011623.1|UniProtKB=W5N0X8 W5N0X8 PTHR24103:SF668 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF CONTAINING 65 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008155.1|UniProtKB=W5MNE2 W5MNE2 PTHR45845:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 4B guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000007044.1|UniProtKB=W5MJG5 W5MJG5 PTHR22802:SF404 C-TYPE LECTIN SUPERFAMILY MEMBER SI:DKEY-9I23.4-RELATED molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004648.1|UniProtKB=W5MB05 W5MB05 PTHR13059:SF13 HMG-BOX TRANSCRIPTION FACTOR BBX PROTEIN CAPICUA HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000002161.1|UniProtKB=W5M2D4 W5M2D4 PTHR13315:SF0 METALLO PHOSPHOESTERASE RELATED METALLOPHOSPHOESTERASE 1 metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008299.1|UniProtKB=W5MNX0 W5MNX0 CFAP418 PTHR33958:SF1 PROTEIN C8ORF37 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 418 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;multicellular organismal process#GO:0032501 ciliary base#GO:0097546;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000013092.1|UniProtKB=W5N677 W5N677 PTHR45627:SF26 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 1 lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975 organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;CCKR signaling map#P06959>Adenylate cyclase#P07127;Gonadotropin-releasing hormone receptor pathway#P06664>AC#P06699;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760 LEPOC|Ensembl=ENSLOCG00000002239.1|UniProtKB=W5M2J1 W5M2J1 PTHR21348:SF4 FAMILY NOT NAMED SULFIREDOXIN-1 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491 cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to oxidative stress#GO:0034599 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000018054.1|UniProtKB=W5NNE6 W5NNE6 PTHR11829:SF392 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN E1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000005482.1|UniProtKB=W5ME22 W5ME22 PTHR12035:SF125 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 5 organic acid binding#GO:0043177;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;binding#GO:0005488;anion binding#GO:0043168;carbohydrate derivative binding#GO:0097367;ion binding#GO:0043167 cell adhesion#GO:0007155;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004350.1|UniProtKB=W5M9Z0 W5M9Z0 PTHR44942:SF9 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN NOVEL PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000000510.1|UniProtKB=W5LWS8 W5LWS8 PTHR12776:SF1 KAZRIN-RELATED KAZRIN LEPOC|Ensembl=ENSLOCG00000012772.1|UniProtKB=W5N515 W5N515 PTHR19134:SF328 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 9 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000005517.1|UniProtKB=W5ME56 W5ME56 PTHR13020:SF28 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6A PROTEIN negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;miRNA-mediated post-transcriptional gene silencing#GO:0035195;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009434.1|UniProtKB=W5MT10 W5MT10 PTHR21669:SF38 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS WASH COMPLEX SUBUNIT 2A-RELATED binding#GO:0005488;phospholipid binding#GO:0005543;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 cytosolic transport#GO:0016482;protein localization to organelle#GO:0033365;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907 intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016467.1|UniProtKB=W5NI86 W5NI86 PTHR47028:SF1 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE O RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE O hydrolase activity, acting on ester bonds#GO:0016788;cell adhesion molecule binding#GO:0050839;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;binding#GO:0005488;phosphoprotein phosphatase activity#GO:0004721;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;neuron development#GO:0048666;axonogenesis#GO:0007409;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell development#GO:0048468;regulation of Wnt signaling pathway#GO:0030111;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;renal system development#GO:0072001;neuron projection development#GO:0031175;kidney development#GO:0001822;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of system process#GO:0044057;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;epithelium development#GO:0060429 cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006523.1|UniProtKB=W5MHL8 W5MHL8 PTHR11348:SF20 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;signaling receptor binding#GO:0005102;integrin binding#GO:0005178;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;carbohydrate derivative binding#GO:0097367 positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of developmental process#GO:0050793;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell motility#GO:2000147 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000011344.1|UniProtKB=W5MZY8 W5MZY8 PTHR10574:SF268 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-3 cell motility#GO:0048870;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;cell-substrate adhesion#GO:0031589;system development#GO:0048731;external encapsulating structure organization#GO:0045229;tissue development#GO:0009888;multicellular organismal process#GO:0032501;extracellular matrix assembly#GO:0085029;cell migration#GO:0016477;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell adhesion#GO:0007155;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;substrate adhesion-dependent cell spreading#GO:0034446 supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000007337.1|UniProtKB=W5MKH8 W5MKH8 PTHR14611:SF1 TECTONIC FAMILY MEMBER TECTONIC-1 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;localization#GO:0051179;organelle assembly#GO:0070925 ciliary transition zone#GO:0035869;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000009845.1|UniProtKB=W5MUH5 W5MUH5 PTHR24034:SF155 EGF-LIKE DOMAIN-CONTAINING PROTEIN MATRILIN 2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000009992.1|UniProtKB=W5MV27 W5MV27 PTHR18934:SF113 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE TDRD9 nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000011103.1|UniProtKB=W5MZ31 W5MZ31 PTHR13044:SF2 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-4 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Apoptosis signaling pathway#P00006>ATF#P00302 LEPOC|Ensembl=ENSLOCG00000012667.1|UniProtKB=W5N4N3 W5N4N3 PTHR11055:SF17 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;oxoacid metabolic process#GO:0043436;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;sulfur compound metabolic process#GO:0006790;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167 LEPOC|Ensembl=ENSLOCG00000008865.1|UniProtKB=W5MQZ1 W5MQZ1 PTHR47979:SF6 DRAB11-RELATED RAB11A, MEMBER RAS ONCOGENE FAMILY, LIKE ISOFORM X1 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 cellular localization#GO:0051641;secretion by cell#GO:0032940;protein transport#GO:0015031;regulation of biological quality#GO:0065008;endocytic recycling#GO:0032456;establishment of organelle localization#GO:0051656;export from cell#GO:0140352;protein localization to membrane#GO:0072657;protein localization to synapse#GO:0035418;endosomal transport#GO:0016197;exocytosis#GO:0006887;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;protein localization to cell periphery#GO:1990778;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;cellular pigmentation#GO:0033059;establishment of protein localization to membrane#GO:0090150;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;secretion#GO:0046903;protein localization to cell junction#GO:1902414;organelle localization#GO:0051640;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;pigmentation#GO:0043473;protein localization to plasma membrane#GO:0072659;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;transport#GO:0006810;biological regulation#GO:0065007;macromolecule localization#GO:0033036;vesicle localization#GO:0051648;endosome to plasma membrane protein transport#GO:0099638 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell junction#GO:0030054;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000014415.1|UniProtKB=W5NAV4 W5NAV4 PTHR23220:SF118 INTEGRIN ALPHA INTEGRIN SUBUNIT ALPHA D signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 cell adhesion molecule#PC00069;integrin#PC00126 LEPOC|Ensembl=ENSLOCG00000014158.1|UniProtKB=W5N9Y2 W5N9Y2 PTHR13723:SF310 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE 5 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000016984.1|UniProtKB=W5NK35 W5NK35 PTHR11348:SF3 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CELLULAR COMMUNICATION NETWORK FACTOR 6 integrin binding#GO:0005178;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;carbohydrate derivative binding#GO:0097367;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;signaling receptor binding#GO:0005102 positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;signaling#GO:0023052 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010636.1|UniProtKB=W5MXC3 W5MXC3 PTHR11685:SF463 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING ANKYRIN REPEAT AND IBR DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003036.1|UniProtKB=W5M5C7 W5M5C7 PTHR11903:SF6 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G_H SYNTHASE 1 dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;fatty acid biosynthetic process#GO:0006633;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;unsaturated fatty acid biosynthetic process#GO:0006636;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;arachidonate metabolic process#GO:0019369;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;prostaglandin metabolic process#GO:0006693 cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 oxygenase#PC00177;oxidoreductase#PC00176 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cyclooxygenase#P00845 LEPOC|Ensembl=ENSLOCG00000017251.1|UniProtKB=W5NL30 W5NL30 PTHR13465:SF3 UPF0183 PROTEIN PROTEIN BROAD-MINDED cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;cellular component organization or biogenesis#GO:0071840 LEPOC|Ensembl=ENSLOCG00000009871.1|UniProtKB=W5MUK7 W5MUK7 PTHR16222:SF23 ADP-RIBOSYLGLYCOHYDROLASE INACTIVE ADP-RIBOSYLTRANSFERASE ARH2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014779.1|UniProtKB=W5NC41 W5NC41 PTHR45805:SF13 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-ALPHA A-RELATED transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000015904.1|UniProtKB=W5NG25 W5NG25 PTHR12430:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20 establishment of RNA localization#GO:0051236;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane translocase complex#GO:0005742 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002436.1|UniProtKB=W5M3B4 W5M3B4 PTHR24073:SF588 DRAB5-RELATED RAS-RELATED PROTEIN RAB-31 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;protein localization to cell periphery#GO:1990778;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;localization#GO:0051179;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;late endosome#GO:0005770;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;early endosome#GO:0005769;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000016667.1|UniProtKB=W5NIX9 W5NIX9 PTHR16525:SF0 PROTEIN C12ORF4 FERRY ENDOSOMAL RAB5 EFFECTOR COMPLEX SUBUNIT 3 regulation of secretion#GO:0051046;regulation of immune effector process#GO:0002697;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of vesicle-mediated transport#GO:0060627;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002893.1|UniProtKB=W5M4V1 W5M4V1 PTHR24061:SF358 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;calcium ion binding#GO:0005509;transmembrane signaling receptor activity#GO:0004888;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;molecular transducer activity#GO:0060089;metal ion binding#GO:0046872 cellular homeostasis#GO:0019725;regulation of transport#GO:0051049;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;regulation of localization#GO:0032879;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;response to metal ion#GO:0010038;response to chemical#GO:0042221;regulation of monoatomic ion transport#GO:0043269;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;detection of stimulus#GO:0051606;response to calcium ion#GO:0051592;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;detection of chemical stimulus#GO:0009593;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015414.1|UniProtKB=W5NEB1 W5NEB1 PTHR45632:SF11 LD33804P KELCH-LIKE PROTEIN 13 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul3-RING ubiquitin ligase complex#GO:0031463;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014499.1|UniProtKB=W5NB39 W5NB39 PTHR45983:SF4 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 18 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011657.1|UniProtKB=W5N117 W5N117 PTHR10693:SF21 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 1 macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;isomerase activity#GO:0016853;helicase activity#GO:0004386;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;DNA helicase activity#GO:0003678;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;binding#GO:0005488;ATP-dependent activity, acting on DNA#GO:0008094 membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840 cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002499.1|UniProtKB=W5M3H5 W5M3H5 PTHR15016:SF6 BREAST CARCINOMA-AMPLIFIED SEQUENCE 1 BREAST CARCINOMA-AMPLIFIED SEQUENCE 1 anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;myelination#GO:0042552;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000001722.1|UniProtKB=W5M0T6 W5M0T6 PTHR46021:SF5 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1 molecular function regulator activity#GO:0098772;phosphatidylinositol phosphate binding#GO:1901981;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;enzyme regulator activity#GO:0030234;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000005209.1|UniProtKB=W5MD21 W5MD21 PTHR10625:SF42 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 7 histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118 CCKR signaling map#P06959>HDAC7#P07235 LEPOC|Ensembl=ENSLOCG00000008651.1|UniProtKB=W5MQ66 W5MQ66 PTHR10361:SF19 SODIUM-BILE ACID COTRANSPORTER ILEAL SODIUM_BILE ACID COTRANSPORTER secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic cation transmembrane transporter activity#GO:0008324;bile acid transmembrane transporter activity#GO:0015125;solute:sodium symporter activity#GO:0015370 bile acid and bile salt transport#GO:0015721;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000003553.1|UniProtKB=W5M746 W5M746 PTHR24246:SF18 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A2B G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;vasodilation#GO:0042311;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of anatomical structure size#GO:0090066;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;blood circulation#GO:0008015;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000010323.1|UniProtKB=W5MW89 W5MW89 PTHR24245:SF7 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 78 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009401.1|UniProtKB=W5MSV8 W5MSV8 PTHR22918:SF1 SEMINAL PLASMA PROTEIN FIBRONECTIN TYPE-II DOMAIN-CONTAINING PROTEIN sperm capacitation#GO:0048240;developmental maturation#GO:0021700;male gamete generation#GO:0048232;cellular process#GO:0009987;cell maturation#GO:0048469;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatid development#GO:0007286;spermatid differentiation#GO:0048515 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000012590.1|UniProtKB=W5N4F0 W5N4F0 PTHR11153:SF20 SIDEROFLEXIN SIDEROFLEXIN-3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular transport#GO:0046907;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;organic acid transport#GO:0015849;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial transmembrane transport#GO:1990542;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000007977.1|UniProtKB=W5MMT4 W5MMT4 PTHR11036:SF85 SEMAPHORIN SEMAPHORIN-1A signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;taxis#GO:0042330;chemotaxis#GO:0006935;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000017429.1|UniProtKB=W5NLM5 W5NLM5 PTHR12002:SF191 CLAUDIN CLAUDIN cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;transport#GO:0006810;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;paracellular transport#GO:0160184;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000003354.1|UniProtKB=W5M6G6 W5M6G6 PTHR14429:SF24 FIBROSIN FAMILY MEMBER FIBROSIN LEPOC|Ensembl=ENSLOCG00000015570.1|UniProtKB=W5NEW1 W5NEW1 PTHR24248:SF145 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(4) DOPAMINE RECEPTOR neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;adrenergic receptor signaling pathway#GO:0071875;negative regulation of cell communication#GO:0010648;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;G protein-coupled dopamine receptor signaling pathway#GO:0007212;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;negative regulation of cellular process#GO:0048523;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015228.1|UniProtKB=W5NDN0 W5NDN0 PTHR24089:SF246 SOLUTE CARRIER FAMILY 25 SOLUTE CARRIER FAMILY 25 MEMBER 43 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000006887.1|UniProtKB=W5MIX1 W5MIX1 PTHR24403:SF36 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 335 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;positive regulation of nervous system development#GO:0051962;central nervous system development#GO:0007417;chromatin remodeling#GO:0006338;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011737.1|UniProtKB=W5N1C7 W5N1C7 PTHR11039:SF48 NEBULIN NEBULETTE protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488 multicellular organismal process#GO:0032501;tissue development#GO:0009888;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;actin filament organization#GO:0007015;developmental process#GO:0032502;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure development#GO:0048856;system development#GO:0048731;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;cellular component assembly#GO:0022607;heart development#GO:0007507;cytoskeleton organization#GO:0007010;cardiac muscle cell differentiation#GO:0055007;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;striated muscle tissue development#GO:0014706;cell differentiation#GO:0030154;circulatory system development#GO:0072359;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108 Z disc#GO:0030018;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;I band#GO:0031674;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017 LEPOC|Ensembl=ENSLOCG00000002515.1|UniProtKB=W5M3I9 W5M3I9 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010514.1|UniProtKB=W5MWX1 W5MWX1 PTHR10250:SF13 MICROSOMAL GLUTATHIONE S-TRANSFERASE MICROSOMAL GLUTATHIONE S-TRANSFERASE 2 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829;glutathione transferase activity#GO:0004364;oxidoreductase activity#GO:0016491;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009177.1|UniProtKB=W5MS36 W5MS36 PTHR19443:SF28 HEXOKINASE HEXOKINASE HKDC1 hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;intracellular chemical homeostasis#GO:0055082;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;carbohydrate metabolic process#GO:0005975;homeostatic process#GO:0042592;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;carbohydrate homeostasis#GO:0033500;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;intracellular glucose homeostasis#GO:0001678;oxoacid metabolic process#GO:0043436;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;cellular homeostasis#GO:0019725;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing small molecule metabolic process#GO:0055086;glucose homeostasis#GO:0042593;purine nucleoside diphosphate catabolic process#GO:0009137;ADP catabolic process#GO:0046032;pyruvate metabolic process#GO:0006090;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytosol#GO:0005829;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasmic side of membrane#GO:0098562 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Hexokinase#P00677;Fructose galactose metabolism#P02744>Hexokinase#P02966;Pentose phosphate pathway#P02762>Hexokinase#P03079 LEPOC|Ensembl=ENSLOCG00000006056.1|UniProtKB=W5MG01 W5MG01 PTHR19343:SF13 T CELL RECEPTOR ALPHA VARIABLE 1-2 IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823;peptide binding#GO:0042277 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001993.1|UniProtKB=W5M1P4 W5M1P4 PTHR12828:SF3 PROTEASOME MATURATION PROTEIN UMP1 PROTEASOME MATURATION PROTEIN cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000010046.1|UniProtKB=W5MV85 W5MV85 PTHR15691:SF6 WASH COMPLEX SUBUNIT 5 WASH COMPLEX SUBUNIT 5 cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;actin filament-based process#GO:0030029;organelle fission#GO:0048285;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;endosome organization#GO:0007032;actin filament organization#GO:0007015 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008917.1|UniProtKB=W5MR50 W5MR50 PTHR35352:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 150 COILED-COIL DOMAIN-CONTAINING PROTEIN 150 LEPOC|Ensembl=ENSLOCG00000005666.1|UniProtKB=W5MEM9 W5MEM9 PTHR28309:SF1 REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014801.1|UniProtKB=W5NC68 W5NC68 PTHR13367:SF9 UBIQUITIN THIOESTERASE OTU DOMAIN-CONTAINING PROTEIN 7A hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 catabolic process#GO:0009056;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002262.1|UniProtKB=W5M2P6 W5M2P6 PTHR10288:SF356 KH DOMAIN CONTAINING RNA BINDING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012014.1|UniProtKB=W5N2C0 W5N2C0 PTHR12183:SF37 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 PROTEIN MDM4 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of developmental process#GO:0051094;negative regulation of cellular process#GO:0048523;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mitochondrion organization#GO:0010821;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of protein stability#GO:0031647;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;protein stabilization#GO:0050821;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of metabolic process#GO:0009892;positive regulation of mitochondrial fission#GO:0090141;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of cellular component organization#GO:0051130 transcription regulator complex#GO:0005667;transcription repressor complex#GO:0017053;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;mitochondrion#GO:0005739;organelle lumen#GO:0043233 p53 pathway#P00059>Mdm2#P01483;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#G04674;P53 pathway feedback loops 1#P04392>Mdm2#P04536;P53 pathway feedback loops 1#P04392>MDM-2#G04682;p53 pathway feedback loops 2#P04398>MDM-2#G04709;p53 pathway feedback loops 2#P04398>Mdm2#P04663;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#P04496;p53 pathway#P00059>MDM-2#G01563 LEPOC|Ensembl=ENSLOCG00000009408.1|UniProtKB=W5MSX3 W5MSX3 PTHR24134:SF33 ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043 CYCLIN-DEPENDENT KINASE 4 INHIBITOR C LEPOC|Ensembl=ENSLOCG00000002539.1|UniProtKB=W5M3N5 W5M3N5 PTHR10625:SF37 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 1 catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215 negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667 p53 pathway#P00059>HDAC1#P04612;Wnt signaling pathway#P00057>Histone deacetylase#P01472 LEPOC|Ensembl=ENSLOCG00000005888.1|UniProtKB=W5MFF3 W5MFF3 PTHR38503:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 1 SMALL INTEGRAL MEMBRANE PROTEIN 1 immune system process#GO:0002376;developmental process#GO:0032502;homeostasis of number of cells#GO:0048872;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;erythrocyte differentiation#GO:0030218;multicellular organismal-level homeostasis#GO:0048871;cellular process#GO:0009987;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;myeloid cell differentiation#GO:0030099;hemopoiesis#GO:0030097;homeostatic process#GO:0042592;cell development#GO:0048468 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000000734.1|UniProtKB=W5LXF4 W5LXF4 PTHR16675:SF237 MHC CLASS I-RELATED MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 major histocompatibility complex protein#PC00149;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005059.1|UniProtKB=W5MCI2 W5MCI2 PTHR23043:SF19 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA SINGLE-MINDED HOMOLOG 2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000015703.1|UniProtKB=W5NFC3 W5NFC3 PTHR15394:SF3 SERINE HYDROLASE RBBP9 SERINE HYDROLASE RBBP9 LEPOC|Ensembl=ENSLOCG00000005712.1|UniProtKB=W5MET8 W5MET8 PTHR23084:SF263 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED MORN REPEAT-CONTAINING PROTEIN 1 kinase#PC00137;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004879.1|UniProtKB=W5MBW0 W5MBW0 PTHR13339:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013403.1|UniProtKB=W5N7B5 W5N7B5 PTHR11043:SF4 ZETA-COAT PROTEIN COATOMER SUBUNIT ZETA-2 intra-Golgi vesicle-mediated transport#GO:0006891;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;COPI-coated vesicle#GO:0030137;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000013641.1|UniProtKB=W5N869 W5N869 PTHR46462:SF1 UPSET, ISOFORM A HISTONE-LYSINE N-METHYLTRANSFERASE SETD5 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 chromosome#GO:0005694;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Rpd3L-Expanded complex#GO:0070210;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000007408.1|UniProtKB=W5MKS9 W5MKS9 PTHR36427:SF5 54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000005759.1|UniProtKB=W5MEZ4 W5MEZ4 PIK3R3 PTHR10155:SF2 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cellular response to peptide hormone stimulus#GO:0071375;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868 membrane protein complex#GO:0098796;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PDGF signaling pathway#P00047>PI3K#P01168;Angiogenesis#P00005>PI3K#P00236;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;PI3 kinase pathway#P00048>p85#P01202;Integrin signalling pathway#P00034>PI3K#P00936;VEGF signaling pathway#P00056>PI3K#P01413;Axon guidance mediated by netrin#P00009>PI3K#P00363;T cell activation#P00053>PI3K#P01322;p53 pathway feedback loops 2#P04398>PI3K#P04661 LEPOC|Ensembl=ENSLOCG00000005335.1|UniProtKB=W5MDH0 W5MDH0 PTHR13509:SF26 SEC61 SUBUNIT BETA PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;localization within membrane#GO:0051668;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of protein localization to endoplasmic reticulum#GO:0072599;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;rough endoplasmic reticulum#GO:0005791;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010500.1|UniProtKB=W5MWW0 W5MWW0 PTHR45752:SF21 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 63 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004190.1|UniProtKB=W5M9E6 W5M9E6 PTHR24409:SF445 ZINC FINGER PROTEIN 142 TRANSCRIPTION FACTOR IIIA DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000017744.1|UniProtKB=W5NMI9 W5NMI9 PTHR24123:SF105 ANKYRIN REPEAT-CONTAINING CARD- AND ANK-DOMAIN CONTAINING INFLAMMASOME ADAPTER PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000198.1|UniProtKB=W5LVR4 W5LVR4 USPL1 PTHR15294:SF3 RETINOVIN-RELATED SUMO-SPECIFIC ISOPEPTIDASE USPL1 binding#GO:0005488;protein binding#GO:0005515 organelle organization#GO:0006996;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular component organization#GO:0016043;cellular process#GO:0009987;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000007560.1|UniProtKB=W5MLB3 W5MLB3 PTHR11576:SF3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA GLYCOPROTEIN 3F, TANDEM DUPLICATE 1 PRECURSOR-RELATED LEPOC|Ensembl=ENSLOCG00000002003.1|UniProtKB=W5M1Q3 W5M1Q3 PTHR23338:SF18 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U4 snRNP#GO:0005687;U2 snRNP#GO:0005686;U5 snRNP#GO:0005682;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;cytoplasm#GO:0005737 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007924.1|UniProtKB=W5MMM7 W5MMM7 PTHR11139:SF133 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE ATR protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 DNA integrity checkpoint signaling#GO:0031570;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;intracellular signal transduction#GO:0035556;telomere organization#GO:0032200;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;organelle organization#GO:0006996;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;double-strand break repair#GO:0006302;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to stress#GO:0033554 chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway#P00059>ATM/ATR#P01481;p53 pathway feedback loops 2#P04398>ATM#P04669 LEPOC|Ensembl=ENSLOCG00000003844.1|UniProtKB=W5M880 W5M880 PTHR13958:SF3 CENTROSOME-ASSOCIATED PROTEIN 350 CAP-GLY DOMAIN-CONTAINING PROTEIN-RELATED non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000003449.1|UniProtKB=W5M6T8 W5M6T8 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000010960.1|UniProtKB=W5MYI9 W5MYI9 PTHR24192:SF3 ANKYRIN REPEAT DOMAIN 40 ANKYRIN REPEAT DOMAIN 40 LEPOC|Ensembl=ENSLOCG00000011920.1|UniProtKB=W5N202 W5N202 PTHR24214:SF0 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 7 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;circulatory system development#GO:0072359;cellular component organization#GO:0016043;system development#GO:0048731;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular process#GO:0009987;organelle organization#GO:0006996;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;myofibril#GO:0030016;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;actomyosin#GO:0042641;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;stress fiber#GO:0001725;I band#GO:0031674;actin filament#GO:0005884;cell junction#GO:0030054;sarcomere#GO:0030017;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;adherens junction#GO:0005912 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000012509.1|UniProtKB=W5N442 W5N442 PTHR31888:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 19 SMALL INTEGRAL MEMBRANE PROTEIN 19 LEPOC|Ensembl=ENSLOCG00000010892.1|UniProtKB=W5MY96 W5MY96 PTHR11783:SF64 SULFOTRANSFERASE SULT SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004829.1|UniProtKB=W5MBP3 W5MBP3 PTHR13624:SF4 RE42071P TRANSMEMBRANE PROTEIN 161A LEPOC|Ensembl=ENSLOCG00000006230.1|UniProtKB=W5MGN8 W5MGN8 PTHR24271:SF80 KALLIKREIN-RELATED GRANZYME 3, TANDEM DUPLICATE 1 ISOFORM X1-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000015093.1|UniProtKB=W5ND73 W5ND73 PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED INTEGRATOR COMPLEX SUBUNIT 6-LIKE protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;integrator complex#GO:0032039;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000000856.1|UniProtKB=W5LXU6 W5LXU6 PTHR40240:SF1 PLEXUS, ISOFORM A PLEXUS, ISOFORM A LEPOC|Ensembl=ENSLOCG00000002935.1|UniProtKB=W5M501 W5M501 PTHR32035:SF3 AURORA KINASE A-INTERACTING PROTEIN SMALL RIBOSOMAL SUBUNIT PROTEIN BS22, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000014701.1|UniProtKB=W5NBT7 W5NBT7 PTHR12697:SF20 PBS LYASE HEAT-LIKE PROTEIN HEAT REPEAT-CONTAINING PROTEIN 4 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000014709.1|UniProtKB=W5NBV0 W5NBV0 PTHR46458:SF2 BLR2807 PROTEIN X GLOBIN molecular carrier activity#GO:0140104;binding#GO:0005488;small molecule binding#GO:0036094 transport#GO:0006810;response to hypoxia#GO:0001666;localization#GO:0051179;establishment of localization#GO:0051234;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002608.1|UniProtKB=W5M3X3 W5M3X3 PTHR11711:SF147 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5A ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166 protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to Golgi apparatus#GO:0034067 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi apparatus subcompartment#GO:0098791 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000010913.1|UniProtKB=W5MYC0 W5MYC0 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010696.1|UniProtKB=W5MXJ0 W5MXJ0 PTHR14971:SF2 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN BINDING PROTEIN VOPP1 protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;vacuole#GO:0005773;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902 LEPOC|Ensembl=ENSLOCG00000006387.1|UniProtKB=W5MH53 W5MH53 PTHR46165:SF2 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 PROTEIN-LYSINE N-METHYLTRANSFERASE SMYD4 protein binding#GO:0005515;histone deacetylase binding#GO:0042826;binding#GO:0005488;enzyme binding#GO:0019899 multicellular organismal process#GO:0032501;heart development#GO:0007507;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system development#GO:0048731 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000009684.1|UniProtKB=W5MTZ2 W5MTZ2 PTHR24020:SF29 COLLAGEN ALPHA COLLAGEN ALPHA-2(VI) CHAIN cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000011053.1|UniProtKB=W5MYV9 W5MYV9 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004209.1|UniProtKB=W5M9H8 W5M9H8 PTHR10217:SF641 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED DELAYED RECTIFIER POTASSIUM CHANNEL KCNH4 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249 transport#GO:0006810;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;potassium ion transport#GO:0006813 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000005468.1|UniProtKB=W5MDZ9 W5MDZ9 PTHR24418:SF42 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE LYN protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;immune response-activating signaling pathway#GO:0002757;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;leukocyte differentiation#GO:0002521;cellular component organization#GO:0016043;immune response-regulating signaling pathway#GO:0002764;mononuclear cell differentiation#GO:1903131;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;cellular response to stress#GO:0033554;immune system development#GO:0002520;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;plasma membrane bounded cell projection organization#GO:0120036;regulation of signal transduction#GO:0009966;immune response-regulating cell surface receptor signaling pathway#GO:0002768;hemopoiesis#GO:0030097;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;DNA damage response#GO:0006974;positive regulation of immune response#GO:0050778;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cell communication#GO:0010646;regulation of B cell receptor signaling pathway#GO:0050855;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of immune response#GO:0050776;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Lyn#P00374;CCKR signaling map#P06959>LYN#P07141;Parkinson disease#P00049>Src kinase#P01230;Cadherin signaling pathway#P00012>Yes#P00476 LEPOC|Ensembl=ENSLOCG00000020998.1|UniProtKB=Q8HQM2 Q8HQM2 PTHR11435:SF1 NADH UBIQUINONE OXIDOREDUCTASE SUBUNIT ND6 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017558.1|UniProtKB=W5NM04 W5NM04 PTHR14499:SF7 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD11 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012847.1|UniProtKB=W5N5B0 W5N5B0 PTHR12424:SF6 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 2 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;chloride channel activity#GO:0005254;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000000500.1|UniProtKB=W5LWP3 W5LWP3 PTHR45786:SF74 DNA BINDING PROTEIN-LIKE ATP-DEPENDENT DNA HELICASE LEPOC|Ensembl=ENSLOCG00000005200.1|UniProtKB=W5MD01 W5MD01 PTHR46902:SF1 DOMON DOMAIN-CONTAINING PROTEIN FRRS1L DOMON DOMAIN-CONTAINING PROTEIN FRRS1L regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000002033.1|UniProtKB=W5M1W0 W5M1W0 PTHR12203:SF18 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 3 glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015626.1|UniProtKB=W5NF29 W5NF29 PTHR46538:SF4 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN STE20-LIKE SERINE_THREONINE-PROTEIN KINASE ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000001454.1|UniProtKB=W5LZW9 W5LZW9 PTHR23280:SF24 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 1 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Nicotine pharmacodynamics pathway#P06587>EPB41L1#P06599;Dopamine receptor mediated signaling pathway#P05912>EPB41L1#P05953;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 LEPOC|Ensembl=ENSLOCG00000015200.1|UniProtKB=W5NDJ8 W5NDJ8 PTHR23344:SF1 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 3 phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000003795.1|UniProtKB=W5M819 W5M819 PTHR15860:SF1 UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNFT1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of ERAD pathway#GO:1904292;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein metabolic process#GO:0051247;regulation of protein catabolic process#GO:0042176;regulation of cellular response to stress#GO:0080135;positive regulation of protein catabolic process#GO:0045732;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of response to stimulus#GO:0048584;regulation of proteasomal protein catabolic process#GO:0061136;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000003867.1|UniProtKB=W5M8B4 W5M8B4 PTHR10281:SF121 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED VACUOLE MEMBRANE PROTEIN 1 intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 Golgi organization#GO:0007030;cellular component organization#GO:0016043;catabolic process#GO:0009056;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macroautophagy#GO:0016236;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007165.1|UniProtKB=W5MK01 W5MK01 PTHR42861:SF18 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE-RELATED primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829 macroautophagy#GO:0016236;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;calcium-mediated signaling#GO:0019722;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;regulation of system process#GO:0044057;regulation of heart contraction#GO:0008016;homeostatic process#GO:0042592;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;vacuole organization#GO:0007033;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;organelle assembly#GO:0070925;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;monoatomic cation transmembrane transport#GO:0098655;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;signal transduction#GO:0007165;autophagy#GO:0006914;monoatomic ion homeostasis#GO:0050801;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;calcium ion transport#GO:0006816;autophagosome assembly#GO:0000045;intracellular calcium ion homeostasis#GO:0006874;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of muscle system process#GO:0090257;monoatomic ion transport#GO:0006811;process utilizing autophagic mechanism#GO:0061919;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;regulation of muscle contraction#GO:0006937 membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000009268.1|UniProtKB=W5MSE3 W5MSE3 PTHR31919:SF1 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013717.1|UniProtKB=W5N8G0 W5N8G0 PTHR12994:SF16 SECERNIN SECERNIN-2 LEPOC|Ensembl=ENSLOCG00000006259.1|UniProtKB=W5MGQ1 W5MGQ1 PTHR21290:SF28 SPHINGOMYELIN SYNTHETASE PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 ceramide metabolic process#GO:0006672;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 LEPOC|Ensembl=ENSLOCG00000009607.1|UniProtKB=W5MTM8 W5MTM8 PTHR14362:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 81 COILED-COIL DOMAIN-CONTAINING PROTEIN 81 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000006736.1|UniProtKB=W5MIC8 W5MIC8 PTHR11485:SF49 TRANSFERRIN OTOLITH MATRIX PROTEIN 1 iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;extracellular region#GO:0005576;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;recycling endosome#GO:0055037 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000000486.1|UniProtKB=W5LWS6 W5LWS6 PTHR24320:SF304 RETINOL DEHYDROGENASE WW DOMAIN-CONTAINING OXIDOREDUCTASE catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 response to endogenous stimulus#GO:0009719;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to growth factor stimulus#GO:0071363 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004689.1|UniProtKB=W5MB57 W5MB57 PTHR11422:SF3 T-CELL SURFACE GLYCOPROTEIN CD4 G6F-LIKE ISOFORM X1 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000012420.1|UniProtKB=W5N3T7 W5N3T7 PTHR46049:SF5 AGAP003327-PA PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000016186.1|UniProtKB=W5NH41 W5NH41 PTHR12183:SF37 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 PROTEIN MDM4 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;positive regulation of developmental process#GO:0051094;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of mitochondrion organization#GO:0010821;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein stability#GO:0031647;positive regulation of biological process#GO:0048518;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of anatomical structure morphogenesis#GO:0022603;protein stabilization#GO:0050821;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;positive regulation of mitochondrial fission#GO:0090141;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;transcription regulator complex#GO:0005667;transcription repressor complex#GO:0017053;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 p53 pathway#P00059>Mdm2#P01483;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#G04674;P53 pathway feedback loops 1#P04392>Mdm2#P04536;P53 pathway feedback loops 1#P04392>MDM-2#G04682;p53 pathway feedback loops 2#P04398>MDM-2#G04709;p53 pathway feedback loops 2#P04398>Mdm2#P04663;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#P04496;p53 pathway#P00059>MDM-2#G01563 LEPOC|Ensembl=ENSLOCG00000013202.1|UniProtKB=W5N6K1 W5N6K1 PTHR23318:SF3 ATP SYNTHASE GAMMA-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3A phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular response to stress#GO:0033554;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of DNA metabolic process#GO:0051052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of response to stress#GO:0080134;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007 organelle#GO:0043226;nucleoplasm#GO:0005654;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000003719.1|UniProtKB=W5M7R1 W5M7R1 PTHR20899:SF1 PIERCE HOMOLOG PIERCER OF MICROTUBULE WALL 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000005247.1|UniProtKB=W5MD61 W5MD61 PTHR12651:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369 protein modifying enzyme#PC00260;protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000013502.1|UniProtKB=W5N7P6 W5N7P6 PTHR15852:SF49 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN PROTEIN SSUH2 HOMOLOG LEPOC|Ensembl=ENSLOCG00000013448.1|UniProtKB=W5N7H0 W5N7H0 PTHR45659:SF11 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B7 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003862.1|UniProtKB=W5M8G1 W5M8G1 PTHR23317:SF71 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 10 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;synapse organization#GO:0050808;regulation of cell communication#GO:0010646;postsynapse organization#GO:0099173;dendritic spine morphogenesis#GO:0060997;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;dendrite morphogenesis#GO:0048813;dendritic spine development#GO:0060996;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;neuron development#GO:0048666;dendrite development#GO:0016358;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;cell development#GO:0048468;cell morphogenesis#GO:0000902;regulation of Rho protein signal transduction#GO:0035023;cell projection organization#GO:0030030;cell differentiation#GO:0030154;neuron projection organization#GO:0106027;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;regulation of small GTPase mediated signal transduction#GO:0051056;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;dendritic spine organization#GO:0097061;neuron projection development#GO:0031175 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000008342.1|UniProtKB=W5MP26 W5MP26 PTHR45849:SF7 FACT COMPLEX SUBUNIT SSRP1 FACT COMPLEX SUBUNIT SSRP1 binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491 biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of chromatin organization#GO:1902275 membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000016576.1|UniProtKB=W5NIL6 W5NIL6 PTHR14517:SF10 RIB43A-RELATED RIB43A-LIKE WITH COILED-COILS PROTEIN 2 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000013548.1|UniProtKB=W5N7U8 W5N7U8 PTHR15109:SF2 AGAP004327-PA PROTEIN FAM193A LEPOC|Ensembl=ENSLOCG00000014867.1|UniProtKB=W5NCF0 W5NCF0 PTHR11003:SF264 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 13 potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215 monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000014022.1|UniProtKB=W5N9I0 W5N9I0 PTHR24173:SF23 ANKYRIN REPEAT CONTAINING UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;apoptotic signaling pathway#GO:0097190;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;negative regulation of intracellular signal transduction#GO:1902532;intrinsic apoptotic signaling pathway#GO:0097193;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;regulation of response to external stimulus#GO:0032101;negative regulation of response to external stimulus#GO:0032102;negative regulation of signal transduction#GO:0009968;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016289.1|UniProtKB=W5NHJ2 W5NHJ2 PTHR21569:SF16 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000006201.1|UniProtKB=W5MGI1 W5MGI1 PTHR23291:SF18 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 2 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 response to unfolded protein#GO:0006986;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;negative regulation of signal transduction#GO:0009968;negative regulation of neuron apoptotic process#GO:0043524;response to stress#GO:0006950;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;endoplasmic reticulum unfolded protein response#GO:0030968;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011415.1|UniProtKB=W5N073 W5N073 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009091.1|UniProtKB=W5MRT8 W5MRT8 PTHR22957:SF536 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 9 enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000011141.1|UniProtKB=W5MZ78 W5MZ78 PTHR13843:SF5 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1B microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;tubulin binding#GO:0015631;protein binding#GO:0005515 regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;dendrite development#GO:0016358;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;neuron projection development#GO:0031175;organelle organization#GO:0006996;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;neuron projection#GO:0043005;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell body#GO:0044297;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;dendrite#GO:0030425 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000009843.1|UniProtKB=W5MUH7 W5MUH7 PTHR20837:SF7 CENTROSOMAL PROTEIN-RELATED COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 2A cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000011294.1|UniProtKB=W5MZS4 W5MZS4 PTHR33662:SF3 OTU DEUBIQUITINASE WITH LINEAR LINKAGE-SPECIFICITY A-RELATED FIBROUS SHEATH CABYR-BINDING PROTEIN ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000016027.1|UniProtKB=W5NGI3 W5NGI3 PTHR11309:SF22 FRIZZLED FRIZZLED-3 Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;non-canonical Wnt signaling pathway#GO:0035567;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>Frizzled#P00475;Angiogenesis#P00005>Fzd#P00189;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Angiogenesis#P00005>FRP#P00237;Wnt signaling pathway#P00057>Frizzled#P01428 LEPOC|Ensembl=ENSLOCG00000001803.1|UniProtKB=W5M140 W5M140 PTHR16089:SF12 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 2 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000007796.1|UniProtKB=W5MM65 W5MM65 PTHR10110:SF61 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 9 potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003 endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;recycling endosome#GO:0055037;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000011714.1|UniProtKB=W5N193 W5N193 PTHR46251:SF4 RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3 RUN DOMAIN-CONTAINING PROTEIN 3A LEPOC|Ensembl=ENSLOCG00000011855.1|UniProtKB=W5N1S1 W5N1S1 PTHR10173:SF37 METHIONINE SULFOXIDE REDUCTASE METHIONINE-R-SULFOXIDE REDUCTASE B2, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000003335.1|UniProtKB=W5M6D3 W5M6D3 PTHR12015:SF155 SMALL INDUCIBLE CYTOKINE A CHEMOKINE (C-C MOTIF) LIGAND 44 cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000001616.1|UniProtKB=W5M0E9 W5M0E9 PTHR13814:SF19 FETUIN FETUIN B endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000017474.1|UniProtKB=W5NLS0 W5NLS0 PTHR31746:SF3 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229B LEPOC|Ensembl=ENSLOCG00000016713.1|UniProtKB=W5NJ41 W5NJ41 PTHR46380:SF2 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004111.1|UniProtKB=W5M973 W5M973 PTHR46184:SF2 UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN UNCONVENTIONAL MYOSIN-IXB ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;cytoskeletal motor activity#GO:0003774;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;ATP binding#GO:0005524;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;actin filament binding#GO:0051015;anion binding#GO:0043168;small molecule binding#GO:0036094;polypeptide conformation or assembly isomerase activity#GO:0120544;ion binding#GO:0043167;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787 plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cellular process#GO:0009987;actin filament-based movement#GO:0030048;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;actin filament-based process#GO:0030029;developmental process#GO:0032502 cytoskeleton#GO:0005856;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;ruffle#GO:0001726;cell leading edge#GO:0031252;supramolecular complex#GO:0099080;lamellipodium#GO:0030027;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000016112.1|UniProtKB=W5NGU4 W5NGU4 PTHR43563:SF14 AMINE OXIDASE AMINE OXIDASE oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000011501.1|UniProtKB=W5N0H3 W5N0H3 PTHR19368:SF15 XLR/SCP3/FAM9 SYNAPTONEMAL COMPLEX PROTEIN 3 spermatogenesis#GO:0007283;developmental process#GO:0032502;meiotic cell cycle#GO:0051321;cellular developmental process#GO:0048869;cellular process#GO:0009987;male gamete generation#GO:0048232;sexual reproduction#GO:0019953;spermatid development#GO:0007286;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;germ cell development#GO:0007281;cell cycle#GO:0007049;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell differentiation#GO:0030154;gamete generation#GO:0007276 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;synaptonemal structure#GO:0099086;condensed chromosome#GO:0000793;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;chromosome#GO:0005694;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000000826.1|UniProtKB=W5LXR5 W5LXR5 PTHR11353:SF22 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ETA macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000004999.1|UniProtKB=W5MCA9 W5MCA9 PTHR19300:SF34 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000818.1|UniProtKB=W5LXQ2 W5LXQ2 PTHR20995:SF17 F-BOX/WD REPEAT-CONTAINING PROTEIN 5 F-BOX_WD REPEAT-CONTAINING PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000000091.1|UniProtKB=W5LVE6 W5LVE6 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013885.1|UniProtKB=W5N914 W5N914 PTHR10281:SF23 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 1 membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010857.1|UniProtKB=W5MY47 W5MY47 PTHR14388:SF5 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 4A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014819.1|UniProtKB=W5NC89 W5NC89 PTHR11683:SF17 MYELIN PROTEOLIPID DMALPHA1 structural molecule activity#GO:0005198 plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;oligodendrocyte differentiation#GO:0048709;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;gliogenesis#GO:0042063;neurogenesis#GO:0022008;myelination#GO:0042552;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cellular component organization#GO:0016043;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;myelin sheath#GO:0043209;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000010267.1|UniProtKB=W5MW19 W5MW19 PTHR23322:SF57 FAS-ASSOCIATED PROTEIN SI:CH73-173P19.1 protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012427.1|UniProtKB=W5N3U0 W5N3U0 PTHR43948:SF6 DNAJ HOMOLOG SUBFAMILY B DNAJ HOMOLOG SUBFAMILY B MEMBER 6 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001351.1|UniProtKB=W5LZI1 W5LZI1 PTHR10130:SF1 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 PEX5-RELATED PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signal sequence receptor activity#GO:0005048 macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;peroxisome organization#GO:0007031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;peroxisomal transport#GO:0043574;protein transport#GO:0015031 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;cytosol#GO:0005829;peroxisome#GO:0005777 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010410.1|UniProtKB=W5MWK3 W5MWK3 PTHR16099:SF5 8-OXO-DGTP DIPHOSPHATES NUDT15 NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15 LEPOC|Ensembl=ENSLOCG00000010818.1|UniProtKB=W5MY01 W5MY01 PTHR24028:SF361 CADHERIN-87A CADHERIN RELATED FAMILY MEMBER 17 cell adhesion#GO:0007155;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000017663.1|UniProtKB=W5NMA9 W5NMA9 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015691.1|UniProtKB=W5NFA6 W5NFA6 MGME1 PTHR31340:SF3 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527 LEPOC|Ensembl=ENSLOCG00000003863.1|UniProtKB=W5M8B8 W5M8B8 PTHR47300:SF1 PROTEIN KASH5 PROTEIN KASH5 binding#GO:0005488;protein-containing complex binding#GO:0044877 chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;actin filament organization#GO:0007015;meiotic nuclear division#GO:0140013;spindle organization#GO:0007051;reproductive process#GO:0022414;actin cytoskeleton organization#GO:0030036;telomere localization#GO:0034397;cell cycle#GO:0007049;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;actin filament-based process#GO:0030029;sexual reproduction#GO:0019953;organelle localization#GO:0051640;organelle assembly#GO:0070925;meiosis I cell cycle process#GO:0061982;chromosome localization#GO:0050000;homologous chromosome pairing at meiosis#GO:0007129;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;cell cycle process#GO:0022402;membraneless organelle assembly#GO:0140694;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;spindle localization#GO:0051653;nuclear division#GO:0000280 microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;synaptonemal structure#GO:0099086;nuclear envelope#GO:0005635;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;nuclear protein-containing complex#GO:0140513;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;bounding membrane of organelle#GO:0098588;nuclear membrane#GO:0031965;organelle lumen#GO:0043233;spindle pole#GO:0000922;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle lumen#GO:0070013;outer membrane#GO:0019867;intracellular organelle#GO:0043229;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;nuclear chromosome#GO:0000228;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;chromosome#GO:0005694;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000004529.1|UniProtKB=W5MAN3 W5MAN3 PTHR24416:SF90 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;signaling receptor binding#GO:0005102;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;catalytic activity#GO:0003824;growth factor receptor binding#GO:0070851;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199 system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;epidermal growth factor receptor signaling pathway#GO:0007173;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;multicellular organism development#GO:0007275;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165 signaling receptor complex#GO:0043235;membrane#GO:0016020;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>EGFR#P00466;Alzheimer disease-presenilin pathway#P00004>Erb-B4 transmembrane fragment#P00113;Alzheimer disease-presenilin pathway#P00004>Erb-B4 C-terminal fragment#P00163;Alzheimer disease-presenilin pathway#P00004>Erb-B4#P00128;Alzheimer disease-presenilin pathway#P00004>Erb-B4 N-terminal fragment#P00148;EGF receptor signaling pathway#P00018>EGFR#P00542 LEPOC|Ensembl=ENSLOCG00000004905.1|UniProtKB=W5MBY9 W5MBY9 PTHR46643:SF1 HOMEOBOX PROTEIN GOOSECOID-RELATED HOMEOBOX PROTEIN GOOSECOID-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000017517.1|UniProtKB=W5NLW3 W5NLW3 PTHR10489:SF735 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 10 protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;locomotion#GO:0040011;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000011945.1|UniProtKB=W5N231 W5N231 PTHR12375:SF28 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN LUC7-LIKE 2-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006981.1|UniProtKB=W5MJA2 W5MJA2 PTHR10913:SF13 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 1 developmental process#GO:0032502;cellular process#GO:0009987;cell differentiation#GO:0030154;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 LEPOC|Ensembl=ENSLOCG00000002257.1|UniProtKB=W5M2P1 W5M2P1 PTHR21077:SF6 EME1 PROTEIN STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT EME2 DNA damage checkpoint signaling#GO:0000077;replication fork processing#GO:0031297;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA integrity checkpoint signaling#GO:0031570;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;resolution of meiotic recombination intermediates#GO:0000712;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;homologous recombination#GO:0035825;reproductive process#GO:0022414;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;DNA replication#GO:0006260;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;meiotic cell cycle process#GO:1903046;negative regulation of cell cycle phase transition#GO:1901988;meiosis I#GO:0007127;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;DNA-templated DNA replication#GO:0006261;negative regulation of mitotic cell cycle#GO:0045930;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554 endonuclease complex#GO:1905348;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000000440.1|UniProtKB=W5LWH3 W5LWH3 PTHR10129:SF54 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAF RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011995.1|UniProtKB=W5N296 W5N296 PTHR23073:SF12 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 8 macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000008912.1|UniProtKB=W5MR43 W5MR43 PTHR13254:SF2 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 GOLGIN SUBFAMILY A MEMBER 7B protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000000121.1|UniProtKB=W5LVH7 W5LVH7 PTHR46013:SF9 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000013799.1|UniProtKB=W5N8Q5 W5N8Q5 PTHR10159:SF305 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 7 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000007183.1|UniProtKB=W5MJY8 W5MJY8 PTHR24068:SF211 UBIQUITIN-CONJUGATING ENZYME E2 AKT-INTERACTING PROTEIN acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015247.1|UniProtKB=W5NDQ6 W5NDQ6 PTHR11523:SF12 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT PROTEIN ATP1B4 ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 import into cell#GO:0098657;chemical homeostasis#GO:0048878;monoatomic cation transmembrane transport#GO:0098655;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;export from cell#GO:0140352;import across plasma membrane#GO:0098739;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;regulation of gene expression#GO:0010468;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;potassium ion homeostasis#GO:0055075;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of DNA-templated transcription#GO:0006355;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 transporter complex#GO:1990351;organelle membrane#GO:0031090;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;nuclear envelope#GO:0005635;membrane#GO:0016020;organelle inner membrane#GO:0019866;cell periphery#GO:0071944;nucleus#GO:0005634;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011071.1|UniProtKB=W5MYZ8 W5MYZ8 PTHR11106:SF72 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000001389.1|UniProtKB=W5LZN6 W5LZN6 PTHR23222:SF1 PROHIBITIN PROHIBITIN-2 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000001085.1|UniProtKB=W5LYL7 W5LYL7 PTHR21669:SF12 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS UBINUCLEIN-1 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005782.1|UniProtKB=W5MF23 W5MF23 PTHR15427:SF29 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT C molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;regulation of immune response#GO:0050776;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;adaptive immune response#GO:0002250;positive regulation of immune system process#GO:0002684;complement activation#GO:0006956;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;immune response#GO:0006955 cellular anatomical structure#GO:0110165;synapse#GO:0045202;extracellular region#GO:0005576;plasma membrane region#GO:0098590;glutamatergic synapse#GO:0098978;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;extracellular protein-containing complex#GO:0140392;synaptic membrane#GO:0097060 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013147.1|UniProtKB=W5N6E6 W5N6E6 PTHR43448:SF2 PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014;cellular process#GO:0009987;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;porphyrin-containing compound biosynthetic process#GO:0006779;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 Heme biosynthesis#P02746>Protoheme IX farnesyl transferase#P02982 LEPOC|Ensembl=ENSLOCG00000012554.1|UniProtKB=W5N4A2 W5N4A2 PTHR11937:SF514 ACTIN ACTIN-RELATED PROTEIN 3B protein binding#GO:0005515;protein-containing complex binding#GO:0044877;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;structural molecule activity#GO:0005198;cytoskeletal protein binding#GO:0008092 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cortical actin cytoskeleton organization#GO:0030866;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 LEPOC|Ensembl=ENSLOCG00000010654.1|UniProtKB=W5MXE3 W5MXE3 PTHR13340:SF2 GATA ZINC FINGER DOMAIN-CONTAINING GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000642.1|UniProtKB=W5LX52 W5LX52 PTHR11505:SF204 L1 TRANSPOSABLE ELEMENT-RELATED L1 TRANSPOSABLE ELEMENT RRM DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000012994.1|UniProtKB=W5N5V7 W5N5V7 PTHR13043:SF1 EXOCYST COMPLEX COMPONENT SEC5 EXOCYST COMPLEX COMPONENT 2 export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;secretion by cell#GO:0032940;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;transport#GO:0006810 vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;exocyst#GO:0000145;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell cortex#GO:0005938;cell periphery#GO:0071944 Ras Pathway#P04393>Sec5#P04545 LEPOC|Ensembl=ENSLOCG00000009700.1|UniProtKB=W5MTZ8 W5MTZ8 PTHR22968:SF9 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE D1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 CCKR signaling map#P06959>PRKD1#P07103;EGF receptor signaling pathway#P00018>PKC#P00565;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 LEPOC|Ensembl=ENSLOCG00000010702.1|UniProtKB=W5MXK0 W5MXK0 PTHR11890:SF51 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR TYPE 1 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005743.1|UniProtKB=W5MEX8 W5MEX8 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;regulation of biological process#GO:0050789;cell communication#GO:0007154;immune system process#GO:0002376 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007596.1|UniProtKB=W5MLF5 W5MLF5 PTHR26451:SF998 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005998.1|UniProtKB=W5MFU2 W5MFU2 PTHR15135:SF2 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN 3 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246 positive regulation of cellular process#GO:0048522;regulation of protein localization to membrane#GO:1905475;positive regulation of biological process#GO:0048518;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;muscle contraction#GO:0006936;system process#GO:0003008;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;muscle system process#GO:0003012;regulation of cellular process#GO:0050794;striated muscle contraction#GO:0006941;skeletal muscle contraction#GO:0003009;nervous system process#GO:0050877;neuromuscular process#GO:0050905;regulation of protein localization#GO:0032880 cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015323.1|UniProtKB=W5NDZ5 W5NDZ5 PTHR45652:SF13 GLIAL FIBRILLARY ACIDIC PROTEIN LOW MOLECULAR WEIGHT NEURONAL INTERMEDIATE FILAMENT structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 cytoskeletal protein#PC00085;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000001800.1|UniProtKB=W5M164 W5M164 PTHR13384:SF19 G PATCH DOMAIN-CONTAINING PROTEIN 1 G PATCH DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003893.1|UniProtKB=W5M8D6 W5M8D6 PTHR24081:SF0 NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B MEMBER 2 transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922 rhythmic process#GO:0048511;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;circadian regulation of gene expression#GO:0032922;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000012363.1|UniProtKB=W5N3M2 W5N3M2 PTHR11616:SF261 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000005254.1|UniProtKB=W5MD83 W5MD83 PTHR23113:SF24 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 3 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of angiogenesis#GO:0045765;positive regulation of angiogenesis#GO:0045766;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of vasculature development#GO:1901342;positive regulation of developmental process#GO:0051094;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000003762.1|UniProtKB=W5M7X2 W5M7X2 PTHR46013:SF9 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000010456.1|UniProtKB=W5MWQ5 W5MWQ5 PTHR46981:SF1 BIS(5'-ADENOSYL)-TRIPHOSPHATASE BIS(5'-ADENOSYL)-TRIPHOSPHATASE hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ubiquitin protein ligase binding#GO:0031625 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;nucleotide catabolic process#GO:0009166;regulation of catabolic process#GO:0009894;apoptotic signaling pathway#GO:0097190;cellular response to stimulus#GO:0051716;cell death#GO:0008219;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;nucleoside phosphate metabolic process#GO:0006753;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteasomal protein catabolic process#GO:1901799;nucleoside phosphate catabolic process#GO:1901292;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;intracellular signal transduction#GO:0035556;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cell communication#GO:0007154;organophosphate catabolic process#GO:0046434;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of protein metabolic process#GO:0051246;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound metabolic process#GO:0072521;apoptotic process#GO:0006915;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;small molecule metabolic process#GO:0044281;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;response to stimulus#GO:0050896;signal transduction by p53 class mediator#GO:0072331;intrinsic apoptotic signaling pathway#GO:0097193;nucleotide metabolic process#GO:0009117 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015042.1|UniProtKB=W5ND11 W5ND11 PTHR23063:SF37 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007352.1|UniProtKB=W5MKL0 W5MKL0 PTHR42735:SF1 FAMILY NOT NAMED PYRIDOXAL-DEPENDENT DECARBOXYLASE DOMAIN-CONTAINING PROTEIN 1-RELATED carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829 catabolic process#GO:0009056;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000013669.1|UniProtKB=W5N896 W5N896 PTHR13524:SF2 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR14 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000011754.1|UniProtKB=W5N1E7 W5N1E7 PTHR45620:SF18 PDF RECEPTOR-LIKE PROTEIN-RELATED PARATHYROID HORMONE_PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005510.1|UniProtKB=W5ME45 W5ME45 PTHR28618:SF1 CENTROSOMAL PROTEIN POC5 CENTROSOMAL PROTEIN POC5 LEPOC|Ensembl=ENSLOCG00000009193.1|UniProtKB=W5MS51 W5MS51 PTHR47966:SF66 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSINOGEN C peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;aspartic protease#PC00053 LEPOC|Ensembl=ENSLOCG00000017385.1|UniProtKB=W5NLI1 W5NLI1 PTHR28612:SF1 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 organelle organization#GO:0006996;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;endomembrane system organization#GO:0010256;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;cellular component organization or biogenesis#GO:0071840;ceramide metabolic process#GO:0006672 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000757.1|UniProtKB=W5LXI4 W5LXI4 PTHR13109:SF8 NEUROCHONDRIN NEUROCHONDRIN cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;cell development#GO:0048468;regulation of cell communication#GO:0010646;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987;regulation of neuronal synaptic plasticity#GO:0048168;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of synaptic plasticity#GO:0048167;neuron differentiation#GO:0030182;developmental process#GO:0032502 neuron projection#GO:0043005;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014667.1|UniProtKB=W5NBP6 W5NBP6 PTHR47437:SF3 JNK-INTERACTING PROTEIN 1-LIKE PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 1 MAP kinase scaffold activity#GO:0005078;structural molecule activity#GO:0005198;molecular adaptor activity#GO:0060090;protein complex scaffold activity#GO:0140378;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000013886.1|UniProtKB=W5N923 W5N923 PTHR12429:SF14 NEURALIZED NEURALIZED-LIKE PROTEIN 4 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 LEPOC|Ensembl=ENSLOCG00000014484.1|UniProtKB=W5NB18 W5NB18 PTHR15641:SF1 ELONGATOR COMPLEX PROTEIN 5 ELONGATOR COMPLEX PROTEIN 5 RNA binding#GO:0003723;tRNA binding#GO:0000049;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;elongator holoenzyme complex#GO:0033588 LEPOC|Ensembl=ENSLOCG00000004074.1|UniProtKB=W5M908 W5M908 PTHR12114:SF6 PARVIN ALPHA-PARVIN binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 cell-substrate adhesion#GO:0031589;cilium organization#GO:0044782;regulation of biological quality#GO:0065008;establishment or maintenance of cell polarity#GO:0007163;organelle assembly#GO:0070925;cell adhesion#GO:0007155;actin filament-based process#GO:0030029;cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036;regulation of developmental process#GO:0050793;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;plasma membrane bounded cell projection assembly#GO:0120031;substrate adhesion-dependent cell spreading#GO:0034446;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987 actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;membraneless organelle#GO:0043228;cell junction#GO:0030054 actin or actin-binding cytoskeletal protein#PC00041;actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Parvin#P00945 LEPOC|Ensembl=ENSLOCG00000006663.1|UniProtKB=W5MI36 W5MI36 PTHR15348:SF2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3C nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000013638.1|UniProtKB=W5N860 W5N860 PTHR22993:SF10 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 3 DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;DNA N-glycosylase activity#GO:0019104;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000004308.1|UniProtKB=W5M9V7 W5M9V7 PTHR14559:SF14 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 11 ISOFORM X1 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of canonical NF-kappaB signal transduction#GO:0043123 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013595.1|UniProtKB=W5N805 W5N805 PTHR28624:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 51 MITOCHONDRIAL POTASSIUM CHANNEL LEPOC|Ensembl=ENSLOCG00000010995.1|UniProtKB=W5MYM8 W5MYM8 PTHR20952:SF4 ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN RETICULOPHAGY REGULATOR 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 process utilizing autophagic mechanism#GO:0061919;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;endoplasmic reticulum tubular network organization#GO:0071786;catabolic process#GO:0009056;endoplasmic reticulum membrane organization#GO:0090158;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;autophagy#GO:0006914;reticulophagy#GO:0061709;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000008413.1|UniProtKB=W5MPB9 W5MPB9 PTHR18063:SF7 NF-E2 INDUCIBLE PROTEIN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-1 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;deubiquitinase activity#GO:0101005 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000013626.1|UniProtKB=W5N840 W5N840 PTHR18063:SF8 NF-E2 INDUCIBLE PROTEIN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-2 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000005277.1|UniProtKB=W5MD98 W5MD98 PTHR31626:SF2 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171B LEPOC|Ensembl=ENSLOCG00000012179.1|UniProtKB=W5N2X1 W5N2X1 PTHR31855:SF2 GUANINE NUCLEOTIDE EXCHANGE C9ORF72 GUANINE NUCLEOTIDE EXCHANGE FACTOR C9ORF72 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;localization#GO:0051179;regulation of metabolic process#GO:0019222;regulation of TOR signaling#GO:0032006;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;transport#GO:0006810;regulation of response to stimulus#GO:0048583;import into cell#GO:0098657;establishment of localization#GO:0051234;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;autophagosome#GO:0005776;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000017302.1|UniProtKB=W5NL98 W5NL98 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009287.1|UniProtKB=W5MSG5 W5MSG5 PTHR36961:SF1 LEUKEMIA-ASSOCIATED PROTEIN 7 LEUKEMIA-ASSOCIATED PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000007148.1|UniProtKB=W5MJU6 W5MJU6 PTHR15614:SF2 INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intraciliary transport particle B#GO:0030992;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000013165.1|UniProtKB=W5N6F7 W5N6F7 PTHR22791:SF14 RING-TYPE DOMAIN-CONTAINING PROTEIN RING FINGER PROTEIN 227 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014557.1|UniProtKB=W5NBB3 W5NBB3 PTHR10267:SF0 DNA POLYMERASE SUBUNIT GAMMA-1 DNA POLYMERASE SUBUNIT GAMMA-1 transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA-directed DNA polymerase activity#GO:0003887;hydrolase activity#GO:0016787;DNA exonuclease activity#GO:0004529;transferase activity#GO:0016740;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;exonuclease activity#GO:0004527;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;mitochondrial DNA metabolic process#GO:0032042;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000009003.1|UniProtKB=W5MRF9 W5MRF9 PTHR10183:SF382 CALPAIN CALPAIN-15 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000014992.1|UniProtKB=W5NCV5 W5NCV5 PTHR10476:SF2 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1B-RELATED late endosome to vacuole transport#GO:0045324;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;macromolecule localization#GO:0033036;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104 vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008202.1|UniProtKB=W5MNK4 W5MNK4 PTHR11941:SF12 ENOYL-COA HYDRATASE-RELATED METHYLGLUTACONYL-COA HYDRATASE, MITOCHONDRIAL hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007687.1|UniProtKB=W5MLT9 W5MLT9 PTHR11848:SF44 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 5 signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 positive regulation of developmental process#GO:0051094;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signaling#GO:0023052;regulation of developmental process#GO:0050793;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;BMP signaling pathway#GO:0030509;response to endogenous stimulus#GO:0009719 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000005778.1|UniProtKB=W5MF20 W5MF20 PTHR11259:SF6 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN C binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of catabolic process#GO:0009895;positive regulation of TOR signaling#GO:0032008;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;positive regulation of TORC1 signaling#GO:1904263;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;nucleus#GO:0005634;lysosome#GO:0005764 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000002133.1|UniProtKB=W5M279 W5M279 PTHR48041:SF90 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 lipid localization#GO:0010876;transmembrane transport#GO:0055085;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;transport#GO:0006810;cholesterol homeostasis#GO:0042632;sterol transport#GO:0015918;establishment of localization#GO:0051234;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cholesterol efflux#GO:0033344;cellular process#GO:0009987;lipid transport#GO:0006869 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017350.1|UniProtKB=W5NLE6 W5NLE6 PTHR19290:SF96 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED OLIGODENDROCYTE TRANSCRIPTION FACTOR 3 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000008001.1|UniProtKB=W5MMW0 W5MMW0 PTHR11959:SF10 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE-LIKE PROTEIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000002899.1|UniProtKB=W5M4W8 W5M4W8 PTHR11584:SF391 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 6 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;p38MAPK cascade#GO:0038066;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>MEKK1-5#P00634 LEPOC|Ensembl=ENSLOCG00000017891.1|UniProtKB=W5NMY5 W5NMY5 PTHR24235:SF19 NEUROPEPTIDE Y RECEPTOR PROLACTIN RELEASING PEPTIDE RECEPTOR-LIKE molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007501.1|UniProtKB=W5ML46 W5ML46 PTHR23024:SF108 ARYLACETAMIDE DEACETYLASE NEUTRAL CHOLESTEROL ESTER HYDROLASE 1 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 membrane#GO:0016020;cellular anatomical structure#GO:0110165 deacetylase#PC00087 LEPOC|Ensembl=ENSLOCG00000002155.1|UniProtKB=W5M2A4 W5M2A4 PTHR46754:SF1 MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000000859.1|UniProtKB=W5LXU9 W5LXU9 PTHR24232:SF85 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003748.1|UniProtKB=W5M7W1 W5M7W1 PTHR46013:SF9 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005839.1|UniProtKB=W5MF89 W5MF89 PTHR24409:SF438 ZINC FINGER PROTEIN 142 CHROMATIN MODIFICATION-RELATED PROTEIN YNG2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000005735.1|UniProtKB=W5MEX0 W5MEX0 PTHR17469:SF1 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN TESPA1 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular component assembly#GO:0022607;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000016416.1|UniProtKB=W5NI16 W5NI16 PTHR28654:SF1 AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;specification of symmetry#GO:0009799;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of protein modification process#GO:0031399;negative regulation of MAPK cascade#GO:0043409;dorsal/ventral pattern formation#GO:0009953;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;regulation of cell communication#GO:0010646;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of protein metabolic process#GO:0051246;negative regulation of signal transduction#GO:0009968;determination of bilateral symmetry#GO:0009855;regulation of MAPK cascade#GO:0043408;regulation of JNK cascade#GO:0046328;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011917.1|UniProtKB=W5N1Z3 W5N1Z3 PTHR46271:SF3 HOMEOBOX PROTEIN, PUTATIVE-RELATED RETINAL HOMEOBOX PROTEIN RX cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011845.1|UniProtKB=W5N1R7 W5N1R7 PTHR18914:SF24 ALPHA CATENIN CATENIN ALPHA-1 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;beta-catenin binding#GO:0008013 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;cell motility#GO:0048870;cell migration#GO:0016477 cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;anchoring junction#GO:0070161;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 Wnt signaling pathway#P00057>alpha-catenin#P01471;Alzheimer disease-presenilin pathway#P00004>alpha-catenin#P00133;Cadherin signaling pathway#P00012>alpha-catenin#P00467 LEPOC|Ensembl=ENSLOCG00000003902.1|UniProtKB=W5M8G0 W5M8G0 PTHR11640:SF136 NEPHRIN NEPHRIN protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000005744.1|UniProtKB=W5MEZ0 W5MEZ0 PTHR24351:SF241 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003749.1|UniProtKB=W5M7V5 W5M7V5 PTHR24369:SF174 ANTIGEN BSP, PUTATIVE-RELATED RETICULON-4 RECEPTOR organic acid binding#GO:0043177;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;lipid binding#GO:0008289;carbohydrate derivative binding#GO:0097367 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015391.1|UniProtKB=W5NE87 W5NE87 PTHR11905:SF262 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 9 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005360.1|UniProtKB=W5MDK1 W5MDK1 PTHR11679:SF85 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole#GO:0000323;vesicle tethering complex#GO:0099023;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000006164.1|UniProtKB=W5MGD7 W5MGD7 SCP2 PTHR24314:SF20 NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED STEROL CARRIER PROTEIN 2 microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000004338.1|UniProtKB=W5M9W9 W5M9W9 PTHR46095:SF1 ZINC FINGER PROTEIN 593 ZINC FINGER PROTEIN 593 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000010906.1|UniProtKB=W5MYC1 W5MYC1 PTHR16027:SF13 DILUTE DOMAIN-CONTAINING PROTEIN YPR089W RAS-ASSOCIATING AND DILUTE DOMAIN-CONTAINING PROTEIN ISOFORM X1-RELATED protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 cell development#GO:0048468;cell differentiation#GO:0030154;cell motility#GO:0048870;cell adhesion#GO:0007155;stem cell development#GO:0048864;animal gross anatomical part developmental process#GO:0160108;cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;cellular process#GO:0009987;neural crest cell migration#GO:0001755;stem cell differentiation#GO:0048863;tissue development#GO:0009888;cell migration#GO:0016477;neural crest cell development#GO:0014032;substrate adhesion-dependent cell spreading#GO:0034446;neural crest cell differentiation#GO:0014033;developmental process#GO:0032502;mesenchymal cell differentiation#GO:0048762;mesenchyme development#GO:0060485;cellular developmental process#GO:0048869;animal organ development#GO:0048513 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000001248.1|UniProtKB=W5LZ59 W5LZ59 PTHR14789:SF2 CHONDROLECTIN VARIANT CHODLFDELTAE. LAYILIN ion binding#GO:0043167;carboxylic acid binding#GO:0031406;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;organic acid binding#GO:0043177 LEPOC|Ensembl=ENSLOCG00000003109.1|UniProtKB=W5M5K6 W5M5K6 PTHR24103:SF688 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000549.1|UniProtKB=W5LWY6 W5LWY6 PTHR24384:SF218 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 519 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000017001.1|UniProtKB=W5NK61 W5NK61 PTHR10694:SF17 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5A histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000006407.1|UniProtKB=W5MH80 W5MH80 PTHR45664:SF5 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-D3 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;skeletal system morphogenesis#GO:0048705;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;embryo development#GO:0009790;anterior/posterior pattern specification#GO:0009952;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;skeletal system development#GO:0001501 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007073.1|UniProtKB=W5MJL2 W5MJL2 PTHR10201:SF29 MATRIX METALLOPROTEINASE 72 KDA TYPE IV COLLAGENASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 multicellular organismal process#GO:0032501;response to stress#GO:0006950;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;response to hypoxia#GO:0001666;metabolic process#GO:0008152;catabolic process#GO:0009056;response to stimulus#GO:0050896;tissue remodeling#GO:0048771;response to abiotic stimulus#GO:0009628;cellular component organization#GO:0016043;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000002275.1|UniProtKB=W5M2R8 W5M2R8 PTHR45677:SF1 GLUTAMATE DECARBOXYLASE-RELATED ACIDIC AMINO ACID DECARBOXYLASE GADL1 carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;lyase activity#GO:0016829 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 LEPOC|Ensembl=ENSLOCG00000006091.1|UniProtKB=W5MG49 W5MG49 PTHR10707:SF13 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 aerobic respiration#GO:0009060;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900 mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transporter complex#GO:1990351;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000000933.1|UniProtKB=W5LY36 W5LY36 PTHR24103:SF326 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM50 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004654.1|UniProtKB=W5MB15 W5MB15 PTHR45255:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 24 DNAJ HOMOLOG SUBFAMILY C MEMBER 24 ferrous iron binding#GO:0008198;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;molecular function activator activity#GO:0140677;metal ion binding#GO:0046872 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001421.1|UniProtKB=W5LZR5 W5LZR5 PTHR13589:SF14 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 1 DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712 response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;cellular response to nitrogen compound#GO:1901699;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>TORC1#P06788 LEPOC|Ensembl=ENSLOCG00000013962.1|UniProtKB=W5N9A4 W5N9A4 PTHR11486:SF72 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 20 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;nervous system development#GO:0007399;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 extracellular region#GO:0005576;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000016874.1|UniProtKB=W5NJQ4 W5NJQ4 PTHR12341:SF41 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;exonuclease activity#GO:0004527;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409 catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 exoribonuclease#PC00099;RNA metabolism protein#PC00031 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 LEPOC|Ensembl=ENSLOCG00000003019.1|UniProtKB=W5M5A2 W5M5A2 PTHR16200:SF2 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE RNF43 G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;signaling receptor binding#GO:0005102;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515 regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000002562.1|UniProtKB=W5M3P8 W5M3P8 PTHR26450:SF429 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003526.1|UniProtKB=W5M710 W5M710 PTHR13481:SF0 SREBP REGULATING GENE PROTEIN SREBP REGULATING GENE PROTEIN LEPOC|Ensembl=ENSLOCG00000005381.1|UniProtKB=W5MDM9 W5MDM9 PTHR13600:SF33 LEUCINE CARBOXYL METHYLTRANSFERASE LEUCINE CARBOXYL METHYLTRANSFERASE 1 O-methyltransferase activity#GO:0008171;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of cell communication#GO:0010646;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular component organization#GO:0051128;regulation of response to stimulus#GO:0048583;regulation of chromosome segregation#GO:0051983;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic cell cycle#GO:0007346;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of signal transduction#GO:0009966;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of chromosome separation#GO:1905818 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000005806.1|UniProtKB=W5MF49 W5MF49 PTHR23320:SF178 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 8-RELATED transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011308.1|UniProtKB=W5MZT8 W5MZT8 PTHR14728:SF2 PROTEIN AURORA BOREALIS PROTEIN AURORA BOREALIS protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900 regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of spindle organization#GO:0090224;regulation of cellular component organization#GO:0051128;regulation of nuclear division#GO:0051783;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of organelle organization#GO:0033043;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;regulation of mitotic spindle organization#GO:0060236;regulation of mitotic nuclear division#GO:0007088;regulation of microtubule-based process#GO:0032886 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013715.1|UniProtKB=W5N8F8 W5N8F8 PTHR24064:SF696 SOLUTE CARRIER FAMILY 22 MEMBER ETT ERGOTHIONEINE TRANSPORTER quaternary ammonium group transmembrane transporter activity#GO:0015651;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014277.1|UniProtKB=W5NAC8 W5NAC8 PTHR12358:SF95 SPHINGOSINE KINASE CERAMIDE KINASE FAMILY PROTEIN lipid kinase activity#GO:0001727;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000007638.1|UniProtKB=W5MLL0 W5MLL0 PTHR45729:SF3 RABPHILIN, ISOFORM A RABPHILIN-3A chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;regulation of exocytosis#GO:0017157;localization#GO:0051179;regulation of secretion#GO:0051046;cell communication#GO:0007154;secretion#GO:0046903;positive regulation of cellular process#GO:0048522;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component organization#GO:0051128;positive regulation of secretion#GO:0051047;positive regulation of cellular component organization#GO:0051130;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulated exocytosis#GO:0045055;positive regulation of vesicle fusion#GO:0031340;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;vesicle-mediated transport in synapse#GO:0099003 postsynaptic membrane#GO:0045211;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;postsynapse#GO:0098794;intracellular vesicle#GO:0097708;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;synaptic membrane#GO:0097060;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;organelle membrane#GO:0031090;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000014855.1|UniProtKB=W5NCD0 W5NCD0 PTHR34490:SF3 PROTEIN CBG12054-RELATED GALAXIN-LIKE REPEATS DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012178.1|UniProtKB=W5N2W6 W5N2W6 PTHR11937:SF592 ACTIN ACTIN, ALPHA, CARDIAC MUSCLE 2 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470 LEPOC|Ensembl=ENSLOCG00000008025.1|UniProtKB=W5MMY5 W5MMY5 PTHR11523:SF47 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3 ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;homeostatic process#GO:0042592;export from cell#GO:0140352;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;potassium ion homeostasis#GO:0055075;inorganic ion homeostasis#GO:0098771 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cation-transporting ATPase complex#GO:0090533;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000012047.1|UniProtKB=W5N2F9 W5N2F9 PTHR46269:SF5 EPIPHYCAN-RELATED OPTICIN bone development#GO:0060348;tissue development#GO:0009888;multicellular organismal process#GO:0032501;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;cartilage development#GO:0051216;connective tissue development#GO:0061448;system development#GO:0048731;animal organ development#GO:0048513;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015741.1|UniProtKB=W5NFG8 W5NFG8 PTHR12241:SF118 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL2-RELATED binding#GO:0005488;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000009963.1|UniProtKB=W5MUX3 W5MUX3 PTHR13100:SF10 CELL GROWTH-REGULATING NUCLEOLAR PROTEIN LYAR CELL GROWTH-REGULATING NUCLEOLAR PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;rRNA processing#GO:0006364;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;negative regulation of DNA-templated transcription#GO:0045892;RNA metabolic process#GO:0016070;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000017524.1|UniProtKB=W5NLX0 W5NLX0 PTHR19297:SF7 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 4 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000001903.1|UniProtKB=W5M1F4 W5M1F4 PTHR32123:SF11 BICD FAMILY-LIKE CARGO ADAPTER BICD FAMILY-LIKE CARGO ADAPTER 2 microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013003.1|UniProtKB=W5N5W0 W5N5W0 PTHR16399:SF18 GASDERMIN GASDERMIN-A transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009713.1|UniProtKB=W5MU10 W5MU10 PTHR45984:SF3 RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG SPERM-ASSOCIATED ANTIGEN 1 protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488 protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003169.1|UniProtKB=W5M5T5 W5M5T5 PTHR20920:SF4 RPE-SPONDIN SMB DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000001667.1|UniProtKB=W5M0M5 W5M0M5 PTHR21433:SF1 TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA TRANSMEMBRANE PROTEIN 120A developmental process#GO:0032502;cellular process#GO:0009987;fat cell differentiation#GO:0045444;cell differentiation#GO:0030154;cellular developmental process#GO:0048869 nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010278.1|UniProtKB=W5MW25 W5MW25 PTHR14491:SF4 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHC LEPOC|Ensembl=ENSLOCG00000007589.1|UniProtKB=W5MLE9 W5MLE9 PTHR24255:SF18 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1S SUBCOMPONENT serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000004824.1|UniProtKB=W5MBN2 W5MBN2 PTHR15729:SF11 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 33 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000000328.1|UniProtKB=W5LW48 W5LW48 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 ISOFORM X1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000005633.1|UniProtKB=W5MEI9 W5MEI9 PTHR31671:SF4 DIABETES AND OBESITY REGULATED, ISOFORM G SI:CH211-260E23.9 transcription regulator activity#GO:0140110;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;transcription coregulator activity#GO:0003712;protein-membrane adaptor activity#GO:0043495;transcription coactivator activity#GO:0003713 regulation of RNA metabolic process#GO:0051252;vacuole organization#GO:0007033;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;organelle assembly#GO:0070925;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macroautophagy#GO:0016236;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;process utilizing autophagic mechanism#GO:0061919;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;autophagosome#GO:0005776;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012838.1|UniProtKB=W5N596 W5N596 PTHR24126:SF3 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016871.1|UniProtKB=W5NJP6 W5NJP6 PTHR45636:SF15 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 embryo development#GO:0009790;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;skeletal system development#GO:0001501;embryo development ending in birth or egg hatching#GO:0009792;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002340.1|UniProtKB=W5M303 W5M303 PTHR23319:SF3 GRAM DOMAIN CONTAINING 1B, ISOFORM E PROTEIN ASTER-B sterol binding#GO:0032934;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;small molecule binding#GO:0036094;binding#GO:0005488;lipid transfer activity#GO:0120013;cholesterol binding#GO:0015485;lipid binding#GO:0008289;transporter activity#GO:0005215;sterol transfer activity#GO:0120015;steroid binding#GO:0005496;alcohol binding#GO:0043178;cholesterol transfer activity#GO:0120020 organic hydroxy compound transport#GO:0015850;sterol transport#GO:0015918;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;lipid localization#GO:0010876;intracellular sterol transport#GO:0032366;lipid transport#GO:0006869;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;organelle membrane contact site#GO:0044232 LEPOC|Ensembl=ENSLOCG00000002165.1|UniProtKB=W5M2B7 W5M2B7 PTHR11586:SF43 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER TYROSINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013287.1|UniProtKB=W5N6X4 W5N6X4 PTHR46961:SF17 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN DYNEIN HEAVY CHAIN, CYTOPLASMIC-LIKE PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008853.1|UniProtKB=W5MQX2 W5MQX2 PTHR19854:SF15 TRANSDUCIN BETA-LIKE 3 TRANSDUCIN BETA-LIKE PROTEIN 3 U3 snoRNA binding#GO:0034511;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;binding#GO:0005488 ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;90S preribosome#GO:0030686;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009957.1|UniProtKB=W5MUW6 W5MUW6 PTHR47266:SF33 ENDONUCLEASE-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000000489.1|UniProtKB=W5LWM8 W5LWM8 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 antigen binding#GO:0003823;binding#GO:0005488 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015810.1|UniProtKB=W5NFQ3 W5NFQ3 PTHR24392:SF60 ZINC FINGER PROTEIN ZINC FINGER Y-CHROMOSOMAL PROTEIN 1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000015900.1|UniProtKB=W5NG27 W5NG27 PTHR10574:SF233 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-1 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515 generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;substrate adhesion-dependent cell spreading#GO:0034446;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular component assembly#GO:0022607;system development#GO:0048731;external encapsulating structure organization#GO:0045229;cell-substrate adhesion#GO:0031589;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;cell motility#GO:0048870;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;extracellular matrix assembly#GO:0085029;cell migration#GO:0016477;multicellular organismal process#GO:0032501;tissue development#GO:0009888 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000002424.1|UniProtKB=W5M387 W5M387 PTHR19836:SF31 30S RIBOSOMAL PROTEIN S14 SMALL RIBOSOMAL SUBUNIT PROTEIN US14M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058 membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000008346.1|UniProtKB=W5MP42 W5MP42 PTHR43107:SF10 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 6 ligase activity, forming carbon-sulfur bonds#GO:0016877;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;monocarboxylic acid transmembrane transporter activity#GO:0008028;catalytic activity#GO:0003824;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857 import into cell#GO:0098657;establishment of localization#GO:0051234;organic acid transport#GO:0015849;lipid metabolic process#GO:0006629;transport#GO:0006810;carboxylic acid transport#GO:0046942;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000016814.1|UniProtKB=W5NJH0 W5NJH0 PTHR11723:SF5 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-2 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nervous system development#GO:0007399;neuron differentiation#GO:0030182;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Id2#P06804 LEPOC|Ensembl=ENSLOCG00000017968.1|UniProtKB=W5NN62 W5NN62 PTHR11462:SF51 JUN TRANSCRIPTION FACTOR-RELATED JUNE PROTO-ONCOGENE, AP-1 TRANSCRIPTION FACTOR SUBUNIT ISOFORM 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 positive regulation of transcription by RNA polymerase II#GO:0045944;response to lipid#GO:0033993;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;response to steroid hormone#GO:0048545;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013398.1|UniProtKB=W5N7A5 W5N7A5 PTHR23268:SF102 T-CELL RECEPTOR BETA CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016878.1|UniProtKB=W5NJQ3 W5NJQ3 PTHR24055:SF260 MITOGEN-ACTIVATED PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE ICK catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular localization#GO:0051641;cilium organization#GO:0044782;microtubule-based transport#GO:0099111;response to stimulus#GO:0050896;cell projection organization#GO:0030030;signaling#GO:0023052;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;localization#GO:0051179;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;organelle assembly#GO:0070925;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;intraciliary transport#GO:0042073;cellular response to stimulus#GO:0051716;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007 cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000014390.1|UniProtKB=W5NAR4 W5NAR4 IMPDH PTHR11911:SF121 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate biosynthetic process#GO:1901293;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 LEPOC|Ensembl=ENSLOCG00000013589.1|UniProtKB=W5N7Z9 W5N7Z9 PTHR11616:SF286 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT NEUTRAL AND BASIC AMINO ACID TRANSPORTER B(0+) neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;quaternary ammonium group transmembrane transporter activity#GO:0015651;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;branched-chain amino acid transmembrane transporter activity#GO:0015658;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324 sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;import into cell#GO:0098657;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000016959.1|UniProtKB=W5NK06 W5NK06 PTHR13572:SF1 ENDO-ALPHA-1,2-MANNOSIDASE GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000017451.1|UniProtKB=W5NLP7 W5NLP7 PTHR26451:SF860 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007478.1|UniProtKB=W5ML25 W5ML25 PTHR13710:SF167 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q4 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;telomere maintenance#GO:0000723;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;telomere organization#GO:0032200 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003910.1|UniProtKB=W5M8F8 W5M8F8 PTHR35085:SF1 KERATINOCYTE DIFFERENTIATION FACTOR 1 KERATINOCYTE DIFFERENTIATION FACTOR 1 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell division#GO:0051302;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000000882.1|UniProtKB=W5LXX9 W5LXX9 PTHR11662:SF459 SOLUTE CARRIER FAMILY 17 SIALIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000015202.1|UniProtKB=W5NDK0 W5NDK0 PTHR12308:SF28 ANOCTAMIN ANOCTAMIN-4 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular process#GO:0009987;macromolecule localization#GO:0033036;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000006519.1|UniProtKB=W5MHL2 W5MHL2 PTHR21399:SF0 CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN METHYLOSOME SUBUNIT PICLN RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 spliceosomal complex#GO:0005681;cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016881.1|UniProtKB=W5NJQ8 W5NJQ8 PTHR16299:SF2 CENTROSOMAL PROTEIN KIZUNA CENTROSOMAL PROTEIN KIZUNA cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000001717.1|UniProtKB=W5M0T7 W5M0T7 PTHR10104:SF17 STATHMIN STATHMIN-3 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;neuron development#GO:0048666;cellular component disassembly#GO:0022411;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;protein depolymerization#GO:0051261;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;microtubule polymerization or depolymerization#GO:0031109;system development#GO:0048731;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;regulation of microtubule-based process#GO:0032886;protein-containing complex disassembly#GO:0032984;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000011383.1|UniProtKB=W5N050 W5N050 PTHR10625:SF41 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 9 catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012306.1|UniProtKB=W5N3E0 W5N3E0 PTHR13024:SF1 MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN, LARGE SUBUNIT MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN LARGE SUBUNIT primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;cellular process#GO:0009987;lipoprotein metabolic process#GO:0042157;homeostatic process#GO:0042592;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;basal part of cell#GO:0045178;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015219.1|UniProtKB=W5NDM4 W5NDM4 PTHR24356:SF160 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 38-LIKE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;establishment or maintenance of cell polarity#GO:0007163;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000003817.1|UniProtKB=W5M847 W5M847 PTHR11537:SF134 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 2 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;action potential#GO:0001508;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;dendritic tree#GO:0097447;dendrite#GO:0030425;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;cell body#GO:0044297;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000014469.1|UniProtKB=W5NB00 W5NB00 PTHR24166:SF28 ROLLING PEBBLES, ISOFORM B ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 46 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009515.1|UniProtKB=W5MTF8 W5MTF8 PTHR13817:SF52 TITIN ROUNDABOUT, AXON GUIDANCE RECEPTOR, HOMOLOG 1 (DROSOPHILA) structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001921.1|UniProtKB=W5M1G8 W5M1G8 PTHR11486:SF30 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;dorsal/ventral pattern formation#GO:0009953;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;pattern specification process#GO:0007389;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;regionalization#GO:0003002;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;response to fibroblast growth factor#GO:0071774;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004979.1|UniProtKB=W5MC90 W5MC90 PTHR19375:SF144 HEAT SHOCK PROTEIN 70KDA ENDOPLASMIC RETICULUM CHAPERONE BIP ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;gene expression#GO:0010467;protein maturation#GO:0051604;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;response to unfolded protein#GO:0006986;protein refolding#GO:0042026;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;protein folding#GO:0006457;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;biosynthetic process#GO:0009058;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule biosynthetic process#GO:0009059;cell communication#GO:0007154;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;endoplasmic reticulum lumen#GO:0005788;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 LEPOC|Ensembl=ENSLOCG00000011704.1|UniProtKB=W5N179 W5N179 PTHR11360:SF14 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 5-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007660.1|UniProtKB=W5MLN9 W5MLN9 PTHR46257:SF4 TYROSINE-PROTEIN PHOSPHATASE CORKSCREW TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6 binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 mitotic cell cycle#GO:0000278;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular process#GO:0009987;cell cycle#GO:0007049 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Interferon-gamma signaling pathway#P00035>PTP#P00960;Angiogenesis#P00005>SHP2#P00181;FGF signaling pathway#P00021>SHP2#P00647;B cell activation#P00010>SHP-1#P00378 LEPOC|Ensembl=ENSLOCG00000017296.1|UniProtKB=W5NL92 W5NL92 PTHR13759:SF9 TWINFILIN TWINFILIN-2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin monomer binding#GO:0003785;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;positive regulation of cell projection organization#GO:0031346;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;regulation of cell projection assembly#GO:0060491;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;protein-containing complex disassembly#GO:0032984;regulation of actin filament depolymerization#GO:0030834;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;protein depolymerization#GO:0051261;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;positive regulation of neuron projection development#GO:0010976;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;cellular component disassembly#GO:0022411;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of anatomical structure size#GO:0090066;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;actin filament depolymerization#GO:0030042;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956 cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;actin filament#GO:0005884 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000005187.1|UniProtKB=W5MCY3 W5MCY3 PTHR14167:SF52 SH3 DOMAIN-CONTAINING ENDOPHILIN-B1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010354.1|UniProtKB=W5MWD0 W5MWD0 PTHR24347:SF391 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005980.1|UniProtKB=W5MFR9 W5MFR9 PTHR31007:SF1 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2 CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2 binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887 kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000015003.1|UniProtKB=W5NCW4 W5NCW4 PTHR24038:SF12 STABILIN STABILIN 2 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000002514.1|UniProtKB=W5M3I8 W5M3I8 PTHR13372:SF3 GEMININ MULTICILIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 cell projection organization#GO:0030030;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of DNA-templated DNA replication#GO:0090329;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;regulation of DNA replication#GO:0006275;organelle assembly#GO:0070925;biological regulation#GO:0065007;regulation of DNA-templated DNA replication initiation#GO:0030174;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000004028.1|UniProtKB=W5M8V2 W5M8V2 PTHR43677:SF13 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016933.1|UniProtKB=W5NK45 W5NK45 PTHR23169:SF24 ENVOPLAKIN DYSTONIN binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 wound healing#GO:0042060;cellular component organization or biogenesis#GO:0071840;intermediate filament-based process#GO:0045103;cytoskeleton organization#GO:0007010;response to stimulus#GO:0050896;intermediate filament cytoskeleton organization#GO:0045104;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;response to wounding#GO:0009611;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;intermediate filament#GO:0005882;cytoskeleton#GO:0005856 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000004202.1|UniProtKB=W5M9G1 W5M9G1 PTHR23003:SF45 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE_ARGININE-RICH SPLICING FACTOR 4 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000004164.1|UniProtKB=W5M9C0 W5M9C0 PTHR11346:SF21 GALECTIN GRIFIN carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000004750.1|UniProtKB=W5MBD7 W5MBD7 PTHR19300:SF67 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 5 galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017188.1|UniProtKB=W5NKT4 W5NKT4 PTHR43157:SF72 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 14-LIKE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000014371.1|UniProtKB=W5NAN7 W5NAN7 PTHR15635:SF11 COILED-COIL DOMAIN CONTAINING PROTEIN 9 COILED-COIL DOMAIN-CONTAINING PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000003651.1|UniProtKB=W5M7H7 W5M7H7 PTHR22984:SF11 SERINE/THREONINE-PROTEIN KINASE PIM PKC_LIKE DOMAIN-CONTAINING PROTEIN ISOFORM X1-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017675.1|UniProtKB=W5NMC1 W5NMC1 PTHR24225:SF48 CHEMOTACTIC RECEPTOR FORMYL PEPTIDE RECEPTOR 2-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;immune response-activating signaling pathway#GO:0002757;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of biological quality#GO:0065008;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003359.1|UniProtKB=W5M6G2 W5M6G2 PTHR24346:SF29 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE NIM1 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;intracellular signal transduction#GO:0035556;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000003620.1|UniProtKB=W5M7D5 W5M7D5 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;sensory system development#GO:0048880;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016505.1|UniProtKB=W5NIC8 W5NIC8 PTHR17223:SF0 PARATHYROID HORMONE-RELATED PARATHYROID HORMONE-RELATED PROTEIN hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;hormone receptor binding#GO:0051427;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 skeletal system development#GO:0001501;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;osteoblast differentiation#GO:0001649;response to stimulus#GO:0050896;cell differentiation#GO:0030154;ossification#GO:0001503;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;signaling#GO:0023052;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;signal transduction#GO:0007165;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000010531.1|UniProtKB=W5MWZ8 W5MWZ8 PTHR45846:SF1 TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000014137.1|UniProtKB=W5N9V4 W5N9V4 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183-LIKE-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012235.1|UniProtKB=W5N341 W5N341 PTHR20854:SF44 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;biological regulation#GO:0065007;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;glycerophospholipid biosynthetic process#GO:0046474;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000016565.1|UniProtKB=W5NIJ9 W5NIJ9 PTHR46470:SF3 N-ACYLNEURAMINATE-9-PHOSPHATASE N-ACYLNEURAMINATE-9-PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000002812.1|UniProtKB=W5M4R4 W5M4R4 PTHR46141:SF1 SODIUM LEAK CHANNEL NON-SELECTIVE PROTEIN SODIUM LEAK CHANNEL NALCN monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of synaptic transmission#GO:0050806 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000007549.1|UniProtKB=W5MLA3 W5MLA3 PTHR15046:SF1 GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN BETA-1,4 N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;glycolipid biosynthetic process#GO:0009247;glycosphingolipid biosynthetic process#GO:0006688;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000000901.1|UniProtKB=W5LXZ4 W5LXZ4 PTHR24232:SF85 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011034.1|UniProtKB=W5MYT0 W5MYT0 PTHR22803:SF155 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED PULMONARY SURFACTANT-ASSOCIATED PROTEIN A-LIKE membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000015593.1|UniProtKB=W5NEY9 W5NEY9 PTHR10653:SF2 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-2 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of actin filament depolymerization#GO:0030834;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835 cell periphery#GO:0071944;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000006744.1|UniProtKB=W5MID8 W5MID8 PTHR24067:SF252 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 U aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 DNA metabolic process#GO:0006259;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to stress#GO:0006950;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;response to stimulus#GO:0050896;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000639.1|UniProtKB=W5LX49 W5LX49 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001000.1|UniProtKB=W5LYB7 W5LYB7 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000008685.1|UniProtKB=W5MQA4 W5MQA4 PTHR19277:SF1 PENTRAXIN NEURONAL PENTRAXIN-2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008388.1|UniProtKB=W5MP80 W5MP80 PTHR45622:SF82 UBIQUITIN-PROTEIN LIGASE E3A-RELATED UBIQUITIN-PROTEIN LIGASE E3A catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 biological regulation#GO:0065007;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000013381.1|UniProtKB=W5N784 W5N784 PTHR23268:SF31 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 30 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014352.1|UniProtKB=W5NAL4 W5NAL4 PTHR46512:SF2 PEPTIDYLPROLYL ISOMERASE PEPTIDYLPROLYL ISOMERASE macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cytosol#GO:0005829;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015284.1|UniProtKB=W5NDU5 W5NDU5 PTHR13450:SF4 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L42 LARGE RIBOSOMAL SUBUNIT PROTEIN ML42 membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000018094.1|UniProtKB=W5NNI6 W5NNI6 PTHR17068:SF2 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER-RELATED LEPOC|Ensembl=ENSLOCG00000000898.1|UniProtKB=W5LXZ2 W5LXZ2 PTHR10924:SF2 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED CHOLINE_ETHANOLAMINE TRANSPORTER FLVCR1 tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488 iron ion transport#GO:0006826;homeostasis of number of cells#GO:0048872;transition metal ion transport#GO:0000041;immune system process#GO:0002376;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;cellular localization#GO:0051641;homeostatic process#GO:0042592;metal ion transport#GO:0030001;cell development#GO:0048468;mitochondrial transport#GO:0006839;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;developmental process#GO:0032502;transport#GO:0006810;iron coordination entity transport#GO:1901678;intracellular transport#GO:0046907;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000018205.1|UniProtKB=W5NNU7 W5NNU7 PTHR26451:SF886 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012782.1|UniProtKB=W5N522 W5N522 PTHR23037:SF27 CYTOKINE RECEPTOR INTERLEUKIN-7 RECEPTOR SUBUNIT ALPHA molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 anatomical structure development#GO:0048856;cell communication#GO:0007154;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cytokine-mediated signaling pathway#GO:0019221;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;developmental process#GO:0032502;biological regulation#GO:0065007;hemopoiesis#GO:0030097;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cell development#GO:0048468;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;interleukin-7-mediated signaling pathway#GO:0038111;cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012334.1|UniProtKB=W5N3H8 W5N3H8 PTHR46379:SF1 ZINC FINGER MYND DOMAIN-CONTAINING ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11 protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;RNA biosynthetic process#GO:0032774;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000004724.1|UniProtKB=W5MBA4 W5MBA4 PTHR10985:SF150 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY-RELATED 2 ISOFORM X1-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000002372.1|UniProtKB=W5M323 W5M323 PTHR12533:SF4 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;calcium-mediated signaling#GO:0019722;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;calcineurin-mediated signaling#GO:0097720;calcineurin-NFAT signaling cascade#GO:0033173;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;intracellular signaling cassette#GO:0141124;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of transcription by RNA polymerase II#GO:0045944;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264;immunoglobulin fold transcription factor#PC00251 Axon guidance mediated by netrin#P00009>NFAT#P00359;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367;Wnt signaling pathway#P00057>NFAT#P01452;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;CCKR signaling map#P06959>NFAT1#P07176 LEPOC|Ensembl=ENSLOCG00000016834.1|UniProtKB=W5NJJ7 W5NJJ7 PTHR31576:SF6 TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription by RNA polymerase I#GO:0006360;rRNA transcription#GO:0009303;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 General transcription by RNA polymerase I#P00022>TAF-IB#P00650 LEPOC|Ensembl=ENSLOCG00000006528.1|UniProtKB=W5MHM8 W5MHM8 PTHR10794:SF39 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD15 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000017219.1|UniProtKB=W5NKY1 W5NKY1 PTHR15431:SF9 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 43 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000015095.1|UniProtKB=W5ND68 W5ND68 PTHR43648:SF3 ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279 regulation of catabolic process#GO:0009894;negative regulation of catabolic process#GO:0009895;regulation of lipid metabolic process#GO:0019216;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of lipid catabolic process#GO:0050994 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000014967.1|UniProtKB=W5NCR7 W5NCR7 PTHR12084:SF0 NUCLEAR PORE GLYCOPROTEIN P62-RELATED NUCLEAR PORE GLYCOPROTEIN P62 binding#GO:0005488;phospholipid binding#GO:0005543;structural molecule activity#GO:0005198;lipid binding#GO:0008289;structural constituent of nuclear pore#GO:0017056 RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear export#GO:0051168;nuclear transport#GO:0051169;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104 nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005148.1|UniProtKB=W5MCU3 W5MCU3 PTHR11447:SF8 CELLULAR TUMOR ANTIGEN P53 TUMOR PROTEIN 63 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 positive regulation of macromolecule metabolic process#GO:0010604;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of apoptotic process#GO:0042981;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;intrinsic apoptotic signaling pathway#GO:0097193;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;regulation of gene expression#GO:0010468;DNA damage response#GO:0006974;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;programmed cell death#GO:0012501;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;P53-like transcription factor#PC00253 Huntington disease#P00029>p53#P00797;p53 pathway#P00059>p53#P01485;p53 pathway feedback loops 2#P04398>p53#P04668;P53 pathway feedback loops 1#P04392>p73DeltaN#G04685;P53 pathway feedback loops 1#P04392>p73DeltaN#P04537;p53 pathway#P00059>p53#G04702;P53 pathway feedback loops 1#P04392>p53#P04539;p53 pathway by glucose deprivation#P04397>p53#P04640 LEPOC|Ensembl=ENSLOCG00000001662.1|UniProtKB=W5M0L2 W5M0L2 PTHR24002:SF5 SOLUTE CARRIER FAMILY 22 MEMBER 18 SOLUTE CARRIER FAMILY 67 MEMBER A1 export from cell#GO:0140352;detoxification#GO:0098754;response to toxic substance#GO:0009636;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;xenobiotic transport#GO:0042908 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014776.1|UniProtKB=W5NC37 W5NC37 PTHR15818:SF2 G PATCH AND KOW-CONTAINING G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000010877.1|UniProtKB=W5MY70 W5MY70 PTHR11119:SF57 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 3 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008560.1|UniProtKB=W5MPV4 W5MPV4 PTHR11653:SF12 PARVALBUMIN ALPHA PARVALBUMIN small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000014742.1|UniProtKB=W5NBZ1 W5NBZ1 PTHR24073:SF315 DRAB5-RELATED RAS-RELATED PROTEIN RAB-29 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000015180.1|UniProtKB=W5NDH1 W5NDH1 PTHR46845:SF3 INSULIN-LIKE GROWTH FACTOR I INSULIN-LIKE GROWTH FACTOR 1 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;insulin-like growth factor receptor signaling pathway#GO:0048009;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell population proliferation#GO:0008283;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896 LEPOC|Ensembl=ENSLOCG00000005236.1|UniProtKB=W5MD53 W5MD53 PTHR10816:SF10 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000014143.1|UniProtKB=W5N9W4 W5N9W4 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015537.1|UniProtKB=W5NER7 W5NER7 PTHR12302:SF2 EBNA2 BINDING PROTEIN P100 STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1 RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000000358.1|UniProtKB=W5LW83 W5LW83 PTHR48071:SF37 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003823.1|UniProtKB=W5M868 W5M868 PTHR24351:SF48 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE BETA-1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;TORC1 signaling#GO:0038202;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to insulin stimulus#GO:0032869;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;TOR signaling#GO:0031929;biological regulation#GO:0065007 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;PI3 kinase pathway#P00048>S6K#P01194;CCKR signaling map#P06959>p70S6K1#P07031;p53 pathway by glucose deprivation#P04397>S6K#P04636;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 LEPOC|Ensembl=ENSLOCG00000013035.1|UniProtKB=W5N605 W5N605 PTHR14920:SF0 OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN WD REPEAT DOMAIN 19 cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;intraciliary transport#GO:0042073;cilium assembly#GO:0060271;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810 intraciliary transport particle#GO:0030990;cilium#GO:0005929;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000007667.1|UniProtKB=W5MLP3 W5MLP3 PTHR20383:SF9 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;termination of RNA polymerase II transcription#GO:0006369;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription termination#GO:0006353;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000005812.1|UniProtKB=W5MF62 W5MF62 PTHR15963:SF1 GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED CYTOHESIN-INTERACTING PROTEIN regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789 cell cortex#GO:0005938;cell periphery#GO:0071944;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015609.1|UniProtKB=W5NF06 W5NF06 PTHR44390:SF1 CENTROSOMAL PROTEIN OF 41 KDA CENTROSOMAL PROTEIN OF 41 KDA cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000016836.1|UniProtKB=W5NJK2 W5NJK2 PTHR16263:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 38 TETRATRICOPEPTIDE REPEAT PROTEIN 38 LEPOC|Ensembl=ENSLOCG00000017750.1|UniProtKB=W5NMJ5 W5NMJ5 PTHR16100:SF4 PHOSPHOINOSITIDE-INTERACTING PROTEIN FAMILY MEMBER PHOSPHOINOSITIDE-INTERACTING PROTEIN ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;transmembrane transporter binding#GO:0044325;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515 regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of system process#GO:0044057 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000011507.1|UniProtKB=W5N0I1 W5N0I1 PTHR21181:SF7 ER membrane protein complex subunit 5-related ER MEMBRANE PROTEIN COMPLEX SUBUNIT 5 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 membrane organization#GO:0061024;endomembrane system organization#GO:0010256;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668 membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000007950.1|UniProtKB=W5MMP9 W5MMP9 PTHR14913:SF0 TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901 cell communication#GO:0007154;apoptotic signaling pathway#GO:0097190;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915;programmed cell death#GO:0012501 signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991 Apoptosis signaling pathway#P00006>TRADD#P00319 LEPOC|Ensembl=ENSLOCG00000000066.1|UniProtKB=W5LVC0 W5LVC0 PTHR15298:SF17 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000015322.1|UniProtKB=W5NDZ7 W5NDZ7 PTHR24418:SF92 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BTK transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Btk#P00400 LEPOC|Ensembl=ENSLOCG00000011200.1|UniProtKB=W5MZG2 W5MZG2 PTHR11532:SF92 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE E catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;carboxypeptidase activity#GO:0004180 peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 Vasopressin synthesis#P04395>Exopeptidase#P04592;CCKR signaling map#P06959>Carboxypeptidase E#P07026 LEPOC|Ensembl=ENSLOCG00000006511.1|UniProtKB=W5MHM5 W5MHM5 PTHR11904:SF26 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278;organophosphate biosynthetic process#GO:0090407;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164;nucleotide metabolic process#GO:0009117 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 kinase#PC00137;nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000017573.1|UniProtKB=W5NM19 W5NM19 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015656.1|UniProtKB=W5NF62 W5NF62 PROSC PTHR10146:SF18 PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363 metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007997.1|UniProtKB=W5MMV5 W5MMV5 PTHR11492:SF3 NUCLEAR FACTOR I NUCLEAR FACTOR 1 X-TYPE DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007552.1|UniProtKB=W5ML97 W5ML97 PTHR12800:SF3 CDC37-RELATED HSP90 CO-CHAPERONE CDC37 heat shock protein binding#GO:0031072;binding#GO:0005488;protein binding#GO:0005515 regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;protein folding#GO:0006457;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of protein stability#GO:0031647;regulation of response to cytokine stimulus#GO:0060759;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to external stimulus#GO:0032101;gene expression#GO:0010467;protein maturation#GO:0051604;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;metabolic process#GO:0008152;protein stabilization#GO:0050821;regulation of cytokine-mediated signaling pathway#GO:0001959;regulation of innate immune response#GO:0045088;macromolecule metabolic process#GO:0043170 protein folding chaperone complex#GO:0101031;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003195.1|UniProtKB=W5M5W6 W5M5W6 PTHR44086:SF14 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED RHODANESE DOMAIN-CONTAINING PROTEIN thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009104.1|UniProtKB=W5MRU6 W5MRU6 PTHR10625:SF33 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 4 deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 cellular process#GO:0009987;regulation of biological process#GO:0050789;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000004397.1|UniProtKB=W5MA41 W5MA41 PTHR48051:SF3 FAMILY NOT NAMED VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8E cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000014938.1|UniProtKB=W5NCN6 W5NCN6 PTHR46983:SF2 CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 INTEGRIN SUBUNIT BETA 1 BINDING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000000250.1|UniProtKB=W5LVW6 W5LVW6 PTHR11599:SF53 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-8 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368 protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009830.1|UniProtKB=W5MUF5 W5MUF5 PTHR12112:SF11 BNIP - RELATED PROTEIN PRUNE HOMOLOG 2 programmed cell death#GO:0012501;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018284.1|UniProtKB=W5NP26 W5NP26 PTHR46272:SF4 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000003111.1|UniProtKB=W5M5L6 W5M5L6 PTHR22028:SF5 SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 191 protein binding#GO:0005515;binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899 LEPOC|Ensembl=ENSLOCG00000005082.1|UniProtKB=W5MCL0 W5MCL0 PTHR14879:SF3 CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF34 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of extrinsic apoptotic signaling pathway#GO:2001236;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013428.1|UniProtKB=W5N7I7 W5N7I7 PTHR10183:SF329 CALPAIN CALPAIN-3 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000014321.1|UniProtKB=W5NAH8 W5NAH8 PTHR43157:SF26 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007577.1|UniProtKB=W5MLD2 W5MLD2 PTHR23235:SF28 KRUEPPEL-LIKE TRANSCRIPTION FACTOR SP5 TRANSCRIPTION FACTOR-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000009773.1|UniProtKB=W5MU82 W5MU82 PTHR48033:SF1 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A_B RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008222.1|UniProtKB=W5MNP0 W5MNP0 PTHR15362:SF15 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 1 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000014959.1|UniProtKB=W5NCR1 W5NCR1 PTHR23336:SF22 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 4 histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone H3 reader activity#GO:0140006;chromatin-protein adaptor activity#GO:0140463 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000004101.1|UniProtKB=W5M943 W5M943 PTHR23504:SF34 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 HIPPOCAMPUS ABUNDANT TRANSCRIPT 1 PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009414.1|UniProtKB=W5MSZ0 W5MSZ0 PTHR46728:SF1 AN1-TYPE ZINC FINGER PROTEIN 4 AN1-TYPE ZINC FINGER PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000014246.1|UniProtKB=W5NA85 W5NA85 PTHR45892:SF1 AMINOACYLASE-1 AMINOACYLASE-1 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 LEPOC|Ensembl=ENSLOCG00000009788.1|UniProtKB=W5MUA6 W5MUA6 PTHR24215:SF23 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 1 structural molecule activity#GO:0005198;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 tissue development#GO:0009888;cellular developmental process#GO:0048869;developmental process#GO:0032502;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108 sarcomere#GO:0030017;membraneless organelle#GO:0043228;I band#GO:0031674;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;nucleus#GO:0005634;Z disc#GO:0030018;myofibril#GO:0030016;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000016252.1|UniProtKB=W5NHD4 W5NHD4 PTHR11533:SF294 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238 metabolic process#GO:0008152;proteolysis#GO:0006508;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004152.1|UniProtKB=W5M9A9 W5M9A9 PTHR43344:SF2 PHOSPHOSERINE PHOSPHATASE PHOSPHOSERINE PHOSPHATASE cation binding#GO:0043169;magnesium ion binding#GO:0000287;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 Serine glycine biosynthesis#P02776>Phosphoserine phosphatase#P03159 LEPOC|Ensembl=ENSLOCG00000001705.1|UniProtKB=W5M0Q9 W5M0Q9 PTHR12939:SF4 SARCOGLYCAN GAMMA-SARCOGLYCAN tissue development#GO:0009888;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;heart development#GO:0007507;animal organ development#GO:0048513;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;heart contraction#GO:0060047;system process#GO:0003008;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;circulatory system development#GO:0072359;heart process#GO:0003015;anatomical structure development#GO:0048856;system development#GO:0048731;muscle tissue development#GO:0060537;animal gross anatomical part developmental process#GO:0160108;circulatory system process#GO:0003013 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;sarcolemma#GO:0042383 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010433.1|UniProtKB=W5MWN0 W5MWN0 PTHR15286:SF16 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 8 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009175.1|UniProtKB=W5MS33 W5MS33 PTHR24346:SF80 MAP/MICROTUBULE AFFINITY-REGULATING KINASE HORMONALLY UP-REGULATED NEU TUMOR-ASSOCIATED KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000004890.1|UniProtKB=W5MBX6 W5MBX6 PTHR11680:SF59 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;carboxylic acid biosynthetic process#GO:0046394;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652 mitochondrion#GO:0005739;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 LEPOC|Ensembl=ENSLOCG00000008509.1|UniProtKB=W5MPQ3 W5MPQ3 PTHR24388:SF45 ZINC FINGER PROTEIN POGO TRANSPOSABLE ELEMENT WITH ZNF DOMAIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000015921.1|UniProtKB=W5NG44 W5NG44 PTHR11848:SF141 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-2 PROPROTEIN signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;response to transforming growth factor beta#GO:0071559;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>TGFbeta#P06778 LEPOC|Ensembl=ENSLOCG00000015956.1|UniProtKB=W5NG88 W5NG88 PTHR28557:SF1 PROTEIN SLX4IP PROTEIN SLX4IP LEPOC|Ensembl=ENSLOCG00000012749.1|UniProtKB=W5N4Y5 W5N4Y5 PTHR14365:SF1 APOPTOSIS REGULATORY PROTEIN SIVA APOPTOSIS REGULATORY PROTEIN SIVA regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;negative regulation of cellular process#GO:0048523;T cell receptor signaling pathway#GO:0050852;multicellular organismal-level homeostasis#GO:0048871;apoptotic signaling pathway#GO:0097190;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cell communication#GO:0010646;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of immune response#GO:0050776;homeostasis of number of cells#GO:0048872;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;lymphocyte homeostasis#GO:0002260;negative regulation of signal transduction#GO:0009968;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;signaling#GO:0023052;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 LEPOC|Ensembl=ENSLOCG00000012548.1|UniProtKB=W5N493 W5N493 PTHR24201:SF7 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR D enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 p53 pathway#P00059>ARF#P01482;p53 pathway#P00059>ARF#G01574 LEPOC|Ensembl=ENSLOCG00000001498.1|UniProtKB=W5M013 W5M013 PTHR24356:SF140 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 3 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell cycle#GO:0051726;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000007034.1|UniProtKB=W5MJK1 W5MJK1 PTHR45703:SF22 DYNEIN HEAVY CHAIN CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000015575.1|UniProtKB=W5NEX0 W5NEX0 PTHR24147:SF53 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN 26 LEPOC|Ensembl=ENSLOCG00000014512.1|UniProtKB=W5NB51 W5NB51 PTHR24410:SF10 HL07962P-RELATED KELCH-LIKE PROTEIN 25 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of lipid metabolic process#GO:0019216;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;positive regulation of metabolic process#GO:0009893 catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005149.1|UniProtKB=W5MCU0 W5MCU0 PTHR12479:SF2 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 5 molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of membrane permeability#GO:0090559 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016138.1|UniProtKB=W5NGX7 W5NGX7 PTHR11909:SF100 CASEIN KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE VRK2 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;response to stress#GO:0006950;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cell communication#GO:0007154 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000008945.1|UniProtKB=W5MR88 W5MR88 PTHR24173:SF14 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG C molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001305.1|UniProtKB=W5LZC5 W5LZC5 PTHR46239:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C DNA REPAIR PROTEIN RAD51 HOMOLOG 3 endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;four-way junction DNA binding#GO:0000400;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 homologous recombination#GO:0035825;reproductive process#GO:0022414;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;sexual reproduction#GO:0019953;nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA repair#GO:0006281;DNA damage response#GO:0006974;response to stimulus#GO:0050896;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;double-strand break repair#GO:0006302;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000013297.1|UniProtKB=W5N6X3 W5N6X3 PTHR14076:SF2 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;coreceptor activity#GO:0015026 signaling#GO:0023052;endocytosis#GO:0006897;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;protein transport#GO:0015031;monoatomic ion transport#GO:0006811;cellular localization#GO:0051641;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;vesicle-mediated transport#GO:0016192;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;establishment of protein localization#GO:0045184;response to hormone#GO:0009725;receptor internalization#GO:0031623;calcium ion transport#GO:0006816;import into cell#GO:0098657;protein localization to cell periphery#GO:1990778;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;localization within membrane#GO:0051668;biological regulation#GO:0065007;macromolecule localization#GO:0033036;receptor-mediated endocytosis#GO:0006898;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810 signaling receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012908.1|UniProtKB=W5N5I6 W5N5I6 PTHR48078:SF19 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED L-SERINE DEAMINASE catalytic activity#GO:0003824;lyase activity#GO:0016829 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039 lyase#PC00144;dehydratase#PC00091 Isoleucine biosynthesis#P02748>Threonine dehydratase#P02995 LEPOC|Ensembl=ENSLOCG00000006046.1|UniProtKB=W5MG32 W5MG32 PTHR11139:SF68 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;somatic cell DNA recombination#GO:0016444;multicellular organismal process#GO:0032501;DNA damage response#GO:0006974;developmental process#GO:0032502;DNA repair#GO:0006281;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;apoptotic signaling pathway#GO:0097190;somatic diversification of immune receptors#GO:0002200;cellular response to stimulus#GO:0051716;cell death#GO:0008219;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;system development#GO:0048731;telomere organization#GO:0032200;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;signal transduction#GO:0007165;somatic recombination of immunoglobulin gene segments#GO:0016447;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;response to stress#GO:0006950;gene expression#GO:0010467;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;V(D)J recombination#GO:0033151;apoptotic process#GO:0006915;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;cellular response to stress#GO:0033554;immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;immune system development#GO:0002520;intrinsic apoptotic signaling pathway#GO:0097193 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000007426.1|UniProtKB=W5MKV9 W5MKV9 PTHR13347:SF1 HEAT REPEAT-CONTAINING PROTEIN 3 HEAT REPEAT-CONTAINING PROTEIN 3 ribonucleoprotein complex biogenesis#GO:0022613;protein localization to organelle#GO:0033365;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;cellular component biogenesis#GO:0044085;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 LEPOC|Ensembl=ENSLOCG00000012385.1|UniProtKB=W5N3P3 W5N3P3 KATNAL2 PTHR23074:SF78 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 2 ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;meiotic cell cycle#GO:0051321;sexual reproduction#GO:0019953;cytoskeleton organization#GO:0007010;reproductive process#GO:0022414;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cellular process#GO:0009987;cell cycle process#GO:0022402 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008301.1|UniProtKB=W5MNX5 W5MNX5 PTHR10165:SF13 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 4 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 developmental process#GO:0032502;lipid metabolic process#GO:0006629;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;lipid modification#GO:0030258;cellular developmental process#GO:0048869;organophosphate metabolic process#GO:0019637;axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;system development#GO:0048731;cell communication#GO:0007154;dephosphorylation#GO:0016311;anatomical structure development#GO:0048856;phospholipid dephosphorylation#GO:0046839;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;metabolic process#GO:0008152;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;phosphate-containing compound metabolic process#GO:0006796;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004917.1|UniProtKB=W5MC16 W5MC16 PTHR19327:SF0 GOLGIN GOLGIN SUBFAMILY A MEMBER 4 small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016551.1|UniProtKB=W5NII2 W5NII2 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000011891.1|UniProtKB=W5N1W0 W5N1W0 PTHR28643:SF1 SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;positive regulation of macromolecule metabolic process#GO:0010604;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;DNA repair#GO:0006281;DNA damage response#GO:0006974;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;recombinational repair#GO:0000725;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000015835.1|UniProtKB=W5NFT6 W5NFT6 PTHR43816:SF3 NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740 purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004090.1|UniProtKB=W5M945 W5M945 PTHR12207:SF8 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4 membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015885.1|UniProtKB=W5NG05 W5NG05 PTHR24390:SF70 ZINC FINGER PROTEIN FEZ FAMILY ZINC FINGER PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002209.1|UniProtKB=W5M2F7 W5M2F7 PTHR46006:SF5 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000001228.1|UniProtKB=W5LZ47 W5LZ47 PTHR11909:SF157 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-2 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 LEPOC|Ensembl=ENSLOCG00000015232.1|UniProtKB=W5NDN4 W5NDN4 PTHR16148:SF15 NF-KAPPA-B-REPRESSING FACTOR-RELATED NF-KAPPA-B-REPRESSING FACTOR ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;molecular function activator activity#GO:0140677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000001476.1|UniProtKB=W5LZZ9 W5LZZ9 PTHR11036:SF72 SEMAPHORIN SEMAPHORIN-4F signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neurogenesis#GO:0022008;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;cellular developmental process#GO:0048869;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;chemotaxis#GO:0006935;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000013699.1|UniProtKB=W5N8D4 W5N8D4 PTHR21275:SF1 RWD DOMAIN-CONTAINING PROTEIN 4 RWD DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000011010.1|UniProtKB=W5MYQ1 W5MYQ1 PTHR15615:SF127 FAMILY NOT NAMED PROTEIN CNPPD1 protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000006807.1|UniProtKB=W5MIL5 W5MIL5 PTHR24103:SF568 E3 UBIQUITIN-PROTEIN LIGASE TRIM B BOX AND SPRY DOMAIN-CONTAINING PROTEIN ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004970.1|UniProtKB=W5MC71 W5MC71 PTHR24373:SF262 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004207.1|UniProtKB=W5M9H0 W5M9H0 PTHR20859:SF55 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON LAMBDA RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375 response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;biological regulation#GO:0065007;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018350.1|UniProtKB=W5NP92 W5NP92 PTHR23349:SF64 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TWIST-RELATED PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000003397.1|UniProtKB=W5M6L2 W5M6L2 PTHR13088:SF3 FAS APOPTOTIC INHIBITORY MOLECULE FAIM FAS APOPTOTIC INHIBITORY MOLECULE 1 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of programmed cell death#GO:0043067;regulation of extrinsic apoptotic signaling pathway#GO:2001236;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of programmed cell death#GO:0043069;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583 LEPOC|Ensembl=ENSLOCG00000013152.1|UniProtKB=W5N6E4 W5N6E4 PTHR22802:SF463 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009960.1|UniProtKB=W5MUY2 W5MUY2 PTHR21345:SF8 SPIRE PROTEIN SPIRE HOMOLOG 1 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 localization#GO:0051179;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;multicellular organismal reproductive process#GO:0048609;organelle localization#GO:0051640;sexual reproduction#GO:0019953;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;reproductive process#GO:0022414;cell cycle#GO:0007049;cell division#GO:0051301;meiotic nuclear division#GO:0140013;establishment of localization#GO:0051234;actin filament organization#GO:0007015;intracellular transport#GO:0046907;transport#GO:0006810;membrane organization#GO:0061024;establishment of spindle localization#GO:0051293;cytoskeleton-dependent cytokinesis#GO:0061640;cellular localization#GO:0051641;spindle localization#GO:0051653;cytokinesis#GO:0000910;nuclear division#GO:0000280;cytokinetic process#GO:0032506;establishment of organelle localization#GO:0051656;gamete generation#GO:0007276;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;meiotic cell cycle#GO:0051321;membrane invagination#GO:0010324;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000002976.1|UniProtKB=W5M547 W5M547 ACTR3 PTHR11937:SF175 ACTIN ACTIN-RELATED PROTEIN 3 structural molecule activity#GO:0005198;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;actin binding#GO:0003779;actin filament binding#GO:0051015 cortical actin cytoskeleton organization#GO:0030866;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987 intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 actin and actin related protein#PC00039 LEPOC|Ensembl=ENSLOCG00000018138.1|UniProtKB=W5NNN0 W5NNN0 PTHR22650:SF7 GLYCOPROTEIN IB BETA PLATELET GLYCOPROTEIN IB BETA CHAIN Blood coagulation#P00011>GP 1bbeta#P00436 LEPOC|Ensembl=ENSLOCG00000011631.1|UniProtKB=W5N0Y8 W5N0Y8 PTHR23504:SF121 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 SOLUTE CARRIER FAMILY 75 MEMBER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cell projection membrane#GO:0031253;cluster of actin-based cell projections#GO:0098862;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;brush border membrane#GO:0031526;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;apical plasma membrane#GO:0016324;membrane#GO:0016020;cell periphery#GO:0071944;brush border#GO:0005903 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000005963.1|UniProtKB=W5MFP1 W5MFP1 PTHR11848:SF130 TGF-BETA FAMILY INHIBIN BETA C CHAIN cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000015858.1|UniProtKB=W5NFW5 W5NFW5 PTHR11769:SF20 HYALURONIDASE HYALURONIDASE PH-20 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;glycosaminoglycan catabolic process#GO:0006027 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000016519.1|UniProtKB=W5NIE5 W5NIE5 PTHR13370:SF3 RNA METHYLASE-RELATED TRNA (GUANINE(10)-N(2))-METHYLTRANSFERASE TRMT11 methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000009857.1|UniProtKB=W5MUJ0 W5MUJ0 PTHR11481:SF112 IMMUNOGLOBULIN FC RECEPTOR BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN ISOFORM X1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;immune response#GO:0006955;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007978.1|UniProtKB=W5MMU5 W5MMU5 PTHR24416:SF306 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672 multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tube development#GO:0035295;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;blood vessel morphogenesis#GO:0048514;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011528.1|UniProtKB=W5N0K9 W5N0K9 PTHR12385:SF12 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002169.1|UniProtKB=W5M2B3 W5M2B3 PTHR24399:SF27 ZINC FINGER AND BTB DOMAIN-CONTAINING HYPERMETHYLATED IN CANCER 2 PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000009768.1|UniProtKB=W5MU79 W5MU79 PTHR43853:SF8 3-KETOACYL-COA THIOLASE, PEROXISOMAL 3-KETOACYL-COA THIOLASE, PEROXISOMAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258 microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000004466.1|UniProtKB=W5MAG5 W5MAG5 PTHR10480:SF8 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG B calmodulin binding#GO:0005516;SNARE binding#GO:0000149;binding#GO:0005488;syntaxin binding#GO:0019905;protein binding#GO:0005515 secretion by cell#GO:0032940;cellular localization#GO:0051641;signaling#GO:0023052;export from cell#GO:0140352;establishment of organelle localization#GO:0051656;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic transmission, glutamatergic#GO:0035249;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;vesicle localization#GO:0051648 neuromuscular junction#GO:0031594;axon terminus#GO:0043679;organelle membrane#GO:0031090;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;axon#GO:0030424;distal axon#GO:0150034;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;neuron projection terminus#GO:0044306;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;synaptic membrane#GO:0097060;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell projection#GO:0042995;intracellular vesicle#GO:0097708 Synaptic vesicle trafficking#P05734>Munc13#P05773 LEPOC|Ensembl=ENSLOCG00000007580.1|UniProtKB=W5MLF9 W5MLF9 PTHR10293:SF74 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-3 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491 inorganic ion homeostasis#GO:0098771;intracellular iron ion homeostasis#GO:0006879;iron-sulfur cluster assembly#GO:0016226;homeostatic process#GO:0042592;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization or biogenesis#GO:0071840;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;cellular component assembly#GO:0022607;monoatomic ion homeostasis#GO:0050801;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000016087.1|UniProtKB=W5NGS1 W5NGS1 PTHR24115:SF398 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF21A protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000007475.1|UniProtKB=W5ML14 W5ML14 PTHR11211:SF3 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX HOMEOBOX PROTEIN MOHAWK cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;muscle organ development#GO:0007517;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008719.1|UniProtKB=W5MQF8 W5MQF8 PTHR44215:SF1 WD REPEAT-CONTAINING PROTEIN 75 WD REPEAT-CONTAINING PROTEIN 75 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase I#GO:0045943;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002286.1|UniProtKB=W5M2W1 W5M2W1 PTHR12809:SF2 MEDIATOR COMPLEX SUBUNIT MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004756.1|UniProtKB=W5MBE9 W5MBE9 PTHR12505:SF21 PHD FINGER TRANSCRIPTION FACTOR TRINUCLEOTIDE REPEAT-CONTAINING GENE 18 PROTEIN DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000014317.1|UniProtKB=W5NAH3 W5NAH3 PTHR10177:SF214 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B3 cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000016695.1|UniProtKB=W5NJ18 W5NJ18 PTHR11766:SF0 TYROSYL-TRNA SYNTHETASE TYROSINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;translation#GO:0006412;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000000191.1|UniProtKB=W5LVQ6 W5LVQ6 PTHR24377:SF1040 IP01015P-RELATED ZINC FINGER PROTEIN 467 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000014394.1|UniProtKB=W5NAR3 W5NAR3 PTHR11588:SF239 TUBULIN TUBULIN ALPHA CHAIN structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 tubulin#PC00228;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000000373.1|UniProtKB=W5LW99 W5LW99 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013862.1|UniProtKB=W5N8Y6 W5N8Y6 PTHR14826:SF6 ANGIOMOTIN ANGIOMOTIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell migration#GO:0016477;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;regulation of cell migration#GO:0030334;developmental process#GO:0032502;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cellular process#GO:0050794;establishment of cell polarity#GO:0030010;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;system development#GO:0048731;intracellular signal transduction#GO:0035556;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;hippo signaling#GO:0035329;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;circulatory system development#GO:0072359;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cytoplasm#GO:0005737;bicellular tight junction#GO:0005923;lamellipodium#GO:0030027 LEPOC|Ensembl=ENSLOCG00000001056.1|UniProtKB=W5LYI4 W5LYI4 PTHR15729:SF12 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 30 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009055.1|UniProtKB=W5NCF3 W5NCF3 PTHR23050:SF427 CALCIUM BINDING PROTEIN CALMODULIN-3 calcium ion binding#GO:0005509;ion binding#GO:0043167;kinase activator activity#GO:0019209;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;signal transduction#GO:0007165;detection of stimulus#GO:0051606;intracellular signaling cassette#GO:0141124;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;response to chemical#GO:0042221;regulation of monoatomic ion transport#GO:0043269;response to metal ion#GO:0010038;regulation of monoatomic cation transmembrane transport#GO:1904062;calcium-mediated signaling#GO:0019722;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular response to stimulus#GO:0051716;detection of chemical stimulus#GO:0009593;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;calcineurin-mediated signaling#GO:0097720;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to calcium ion#GO:0051592 organelle#GO:0043226;cellular anatomical structure#GO:0110165;myelin sheath#GO:0043209;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 calcium-binding protein#PC00060;calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 LEPOC|Ensembl=ENSLOCG00000012489.1|UniProtKB=W5N414 W5N414 PTHR11040:SF211 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP11 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000005231.1|UniProtKB=W5MD39 W5MD39 PTHR31525:SF1 HEME TRANSPORTER HRG1 HEME TRANSPORTER HRG1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;heme binding#GO:0020037;binding#GO:0005488;tetrapyrrole binding#GO:0046906 metal ion transport#GO:0030001;nitrogen compound transport#GO:0071705;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;iron coordination entity transport#GO:1901678;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810 vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011748.1|UniProtKB=W5N1D6 W5N1D6 PTHR43675:SF37 ARSENITE METHYLTRANSFERASE ARSENITE METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;small molecule metabolic process#GO:0044281;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;secondary metabolic process#GO:0019748;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000007781.1|UniProtKB=W5MM52 W5MM52 PTHR45954:SF3 LD33695P G PROTEIN-SIGNALING MODULATOR 2 binding#GO:0005488;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;spindle localization#GO:0051653;localization#GO:0051179;organelle localization#GO:0051640;establishment or maintenance of cell polarity#GO:0007163;establishment of organelle localization#GO:0051656;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell cycle process#GO:0022402;establishment of cell polarity#GO:0030010;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;cellular component organization or biogenesis#GO:0071840;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cytoskeleton organization#GO:0007010;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of spindle localization#GO:0051293 cell periphery#GO:0071944;cell cortex#GO:0005938;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>AGS3#P00715;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>AGS3#P00739 LEPOC|Ensembl=ENSLOCG00000015555.1|UniProtKB=W5NEU1 W5NEU1 PTHR43381:SF20 TRANSLATION INITIATION FACTOR IF-2-RELATED TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000013520.1|UniProtKB=W5N7R2 W5N7R2 PTHR12696:SF2 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 2 cellular component assembly#GO:0022607;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein modification by small protein conjugation#GO:0032446;protein-containing complex assembly#GO:0065003;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001068.1|UniProtKB=W5LYL2 W5LYL2 PTHR13140:SF663 MYOSIN UNCONVENTIONAL MYOSIN-IF isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;cytoskeleton organization#GO:0007010;transport#GO:0006810;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000008174.1|UniProtKB=W5MNG5 W5MNG5 PTHR23163:SF2 RING FINGER PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE BRE1A catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000002184.1|UniProtKB=W5M2F8 W5M2F8 PTHR46304:SF1 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004299.1|UniProtKB=W5M9T0 W5M9T0 PTHR45889:SF3 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 4 protein binding#GO:0005515;growth factor receptor binding#GO:0070851;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488 regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of small GTPase mediated signal transduction#GO:0051056;cellular process#GO:0009987;regulation of response to wounding#GO:1903034;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of wound healing#GO:0061041;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cell-cell contact zone#GO:0044291;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 LEPOC|Ensembl=ENSLOCG00000018364.1|UniProtKB=W5NPA6 W5NPA6 PTHR13832:SF779 PROTEIN PHOSPHATASE 2C [PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000012822.1|UniProtKB=W5N566 W5N566 PTHR24346:SF122 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000003182.1|UniProtKB=W5M5V5 W5M5V5 PTHR15722:SF7 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;microtubule-based transport#GO:0099111;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630;intraciliary transport particle A#GO:0030991;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014177.1|UniProtKB=W5NA14 W5NA14 PTHR24416:SF45 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301 regulation of vasculature development#GO:1901342;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;endothelial cell differentiation#GO:0045446;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;epithelium development#GO:0060429;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;cell migration#GO:0016477;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;regulation of angiogenesis#GO:0045765;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;angiogenesis#GO:0001525;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;positive regulation of angiogenesis#GO:0045766;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;cell differentiation#GO:0030154;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VEGFR-2#P00222;VEGF signaling pathway#P00056>VEGFR-2#P01403 LEPOC|Ensembl=ENSLOCG00000014264.1|UniProtKB=W5NA99 W5NA99 PTHR23280:SF34 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000013330.1|UniProtKB=W5N721 W5N721 PTHR20932:SF4 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 2-RELATED LEPOC|Ensembl=ENSLOCG00000014536.1|UniProtKB=W5NB83 W5NB83 PTHR13374:SF3 DET1 HOMOLOG DE-ETIOLATED-1 HOMOLOG DET1 HOMOLOG enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like protein ligase binding#GO:0044389;molecular adaptor activity#GO:0060090;ubiquitin protein ligase binding#GO:0031625;enzyme binding#GO:0019899;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein binding#GO:0005515 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;primary metabolic process#GO:0044238;protein modification process#GO:0036211;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;metabolic process#GO:0008152;regulation of ubiquitin-dependent protein catabolic process#GO:2000058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017406.1|UniProtKB=W5NLK2 W5NLK2 PTHR24228:SF11 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR TYPE-1 ANGIOTENSIN II RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;renal system development#GO:0072001;kidney development#GO:0001822;response to hormone#GO:0009725;response to stress#GO:0006950;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;response to nitrogen compound#GO:1901698;circulatory system process#GO:0003013;inflammatory response#GO:0006954;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;regulation of blood pressure#GO:0008217;system process#GO:0003008;defense response#GO:0006952;developmental process#GO:0032502 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>AT1-R#P05924 LEPOC|Ensembl=ENSLOCG00000004102.1|UniProtKB=W5M950 W5M950 PTHR23167:SF39 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL2 actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;protein depolymerization#GO:0051261;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;cellular component organization#GO:0016043;organelle organization#GO:0006996 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005662.1|UniProtKB=W5MEN2 W5MEN2 PTHR24055:SF380 MITOGEN-ACTIVATED PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE NLK protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Nemo-like Kinase#P01449 LEPOC|Ensembl=ENSLOCG00000006934.1|UniProtKB=W5MJ35 W5MJ35 PTHR24240:SF126 OPSIN NOVOPSIN-10 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;biological regulation#GO:0065007;detection of stimulus#GO:0051606;signal transduction#GO:0007165;response to radiation#GO:0009314;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016376.1|UniProtKB=W5NHW9 W5NHW9 PTHR11757:SF23 PROTEASE FAMILY S9A OLIGOPEPTIDASE PROLYL ENDOPEPTIDASE-LIKE Golgi vesicle transport#GO:0048193;transport#GO:0006810;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;Golgi to plasma membrane protein transport#GO:0043001;cytosolic transport#GO:0016482;Golgi to plasma membrane transport#GO:0006893 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoskeleton#GO:0005856 serine protease#PC00203 Vasopressin synthesis#P04395>Endo Peptidase#P04596 LEPOC|Ensembl=ENSLOCG00000016283.1|UniProtKB=W5NHI2 W5NHI2 PTHR10024:SF239 SYNAPTOTAGMIN SYNAPTOTAGMIN-1 protein binding#GO:0005515;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 signal release#GO:0023061;trans-synaptic signaling#GO:0099537;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;signaling#GO:0023052;export from cell#GO:0140352;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of cellular component organization#GO:0051128;regulation of neurotransmitter secretion#GO:0046928;regulated exocytosis#GO:0045055;positive regulation of vesicle fusion#GO:0031340;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177 organelle membrane#GO:0031090;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;neuron projection#GO:0043005;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell projection#GO:0042995;intracellular vesicle#GO:0097708 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000017949.1|UniProtKB=W5NN43 W5NN43 PTHR24156:SF6 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN 34C LEPOC|Ensembl=ENSLOCG00000009975.1|UniProtKB=W5MUY9 W5MUY9 PTHR12247:SF139 POLYCOMB GROUP PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING 1A-RELATED binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008282.1|UniProtKB=W5MNX6 W5MNX6 PTHR43568:SF2 P PROTEIN P PROTEIN biosynthetic process#GO:0009058;cellular process#GO:0009987;developmental pigmentation#GO:0048066;melanocyte differentiation#GO:0030318;phenol-containing compound biosynthetic process#GO:0046189;pigment metabolic process#GO:0042440;secondary metabolic process#GO:0019748;cellular developmental process#GO:0048869;developmental process#GO:0032502;pigment biosynthetic process#GO:0046148;metabolic process#GO:0008152;secondary metabolite biosynthetic process#GO:0044550;cell differentiation#GO:0030154;phenol-containing compound metabolic process#GO:0018958;melanin biosynthetic process#GO:0042438;pigmentation#GO:0043473 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;melanosome#GO:0042470;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011271.1|UniProtKB=W5MZP3 W5MZP3 PTHR11085:SF9 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1 transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407;transferase activity#GO:0016740;deacylase activity#GO:0160215;transcription coregulator activity#GO:0003712;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;transcription regulator activity#GO:0140110;acyltransferase activity#GO:0016746;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213 cellular process#GO:0009987;response to stress#GO:0006950;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 heterochromatin#GO:0000792;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;nucleus#GO:0005634;chromatin#GO:0000785;organelle inner membrane#GO:0019866;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;organelle envelope#GO:0031967;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 p53 pathway#P00059>SIRT-1#P04632 LEPOC|Ensembl=ENSLOCG00000016085.1|UniProtKB=W5NGR0 W5NGR0 PTHR12307:SF15 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3C carbohydrate binding#GO:0030246;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;polysaccharide binding#GO:0030247;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899 regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000011800.1|UniProtKB=W5N1J7 W5N1J7 PTHR31159:SF1 COMM DOMAIN-CONTAINING PROTEIN 3 COMM DOMAIN-CONTAINING PROTEIN 3 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000016295.1|UniProtKB=W5NHJ9 W5NHJ9 PTHR24399:SF0 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 2 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008680.1|UniProtKB=W5MQC8 W5MQC8 PTHR11733:SF127 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED EEF1AKMT4-ECE2 READTHROUGH TRANSCRIPT PROTEIN-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 LEPOC|Ensembl=ENSLOCG00000011835.1|UniProtKB=W5N1P6 W5N1P6 PTHR43104:SF2 L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000012929.1|UniProtKB=W5N5L2 W5N5L2 PTHR17469:SF14 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN ITPRID1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000017090.1|UniProtKB=W5NKG5 W5NKG5 PTHR31518:SF3 ARGININE/SERINE-RICH PROTEIN PNISR ARGININE_SERINE-RICH PROTEIN PNISR LEPOC|Ensembl=ENSLOCG00000017185.1|UniProtKB=W5NKT1 W5NKT1 PTHR14196:SF5 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED-RELATED 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;kidney development#GO:0001822;renal system development#GO:0072001;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014003.1|UniProtKB=W5N9F3 W5N9F3 PTHR23404:SF3 MOLYBDOPTERIN SYNTHASE RELATED MAP3K12-BINDING INHIBITORY PROTEIN 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000010204.1|UniProtKB=W5MVT3 W5MVT3 PTHR15106:SF4 RETINOIC ACID RECEPTOR RESPONDER PROTEIN 2 RETINOIC ACID RECEPTOR RESPONDER PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000008379.1|UniProtKB=W5MP73 W5MP73 PTHR16230:SF6 CAPPUCCINO BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 4 cellular pigmentation#GO:0033059;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;pigmentation#GO:0043473;melanosome organization#GO:0032438 BLOC-1 complex#GO:0031083;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000009257.1|UniProtKB=W5MSD1 W5MSD1 PTHR35347:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 175 COILED-COIL DOMAIN-CONTAINING PROTEIN 175 LEPOC|Ensembl=ENSLOCG00000015408.1|UniProtKB=W5NEA9 W5NEA9 PTHR11388:SF99 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1C1 active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016760.1|UniProtKB=W5NJA6 W5NJA6 PTHR10270:SF210 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-7 sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676 positive regulation of RNA metabolic process#GO:0051254;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000015172.1|UniProtKB=W5NDG0 W5NDG0 PTHR11473:SF44 AROMATIC AMINO ACID HYDROXYLASE PHENYLALANINE-4-HYDROXYLASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;aromatic amino acid biosynthetic process#GO:0009073;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011616.1|UniProtKB=W5N0W6 W5N0W6 PTHR45624:SF61 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179 establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;cellular localization#GO:0051641;mitochondrial transmembrane transport#GO:1990542;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;L-alpha-amino acid transmembrane transport#GO:1902475 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005377.1|UniProtKB=W5MDM7 W5MDM7 PTHR13923:SF22 SEC31-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC31B establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114;cellular component organization#GO:0016043 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796 membrane traffic protein#PC00150;vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000009429.1|UniProtKB=W5MT03 W5MT03 PTHR24240:SF178 OPSIN ADENOSINE RECEPTOR A3 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to radiation#GO:0071478;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;cellular process#GO:0009987;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;signal transduction#GO:0007165;detection of stimulus#GO:0051606;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013096.1|UniProtKB=W5N672 W5N672 PTHR24343:SF477 SERINE/THREONINE KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008547.1|UniProtKB=W5MPT5 W5MPT5 PTHR22792:SF71 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 6 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014293.1|UniProtKB=W5NAD7 W5NAD7 PTHR21646:SF6 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000010495.1|UniProtKB=W5MWV8 W5MWV8 PTHR21614:SF0 SHORT COILED COIL PROTEIN SHORT COILED-COIL PROTEIN organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000009477.1|UniProtKB=W5MT58 W5MT58 PTHR18945:SF883 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A ISOFORM X1 monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276 metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;response to nitrogen compound#GO:1901698;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;establishment of localization#GO:0051234;transport#GO:0006810;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;signaling receptor complex#GO:0043235;cation channel complex#GO:0034703;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000012796.1|UniProtKB=W5N564 W5N564 PTHR13140:SF356 MYOSIN UNCONVENTIONAL MYOSIN-VB macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 membrane#GO:0016020;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000006346.1|UniProtKB=W5MH01 W5MH01 PTHR10224:SF16 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000001977.1|UniProtKB=W5M1N0 W5M1N0 PTHR24126:SF69 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 65-LIKE LEPOC|Ensembl=ENSLOCG00000013640.1|UniProtKB=W5N863 W5N863 PTHR23239:SF180 INTERMEDIATE FILAMENT KERATIN 96-RELATED structural molecule activity#GO:0005198 anatomical structure morphogenesis#GO:0009653;epithelium development#GO:0060429;tissue development#GO:0009888;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;morphogenesis of an epithelium#GO:0002009 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000009361.1|UniProtKB=W5MSQ8 W5MSQ8 PTHR11934:SF0 RIBOSE-5-PHOSPHATE ISOMERASE RIBOSE-5-PHOSPHATE ISOMERASE intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;ribose-5-phosphate isomerase activity#GO:0004751 nucleotide metabolic process#GO:0009117;NADPH regeneration#GO:0006740;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pyridine-containing compound metabolic process#GO:0072524;pentose-phosphate shunt#GO:0006098;pentose-phosphate shunt, non-oxidative branch#GO:0009052;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;generation of precursor metabolites and energy#GO:0006091;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;isomerase#PC00135 Pentose phosphate pathway#P02762>Ribulose 5-P Isomerase#P03071 LEPOC|Ensembl=ENSLOCG00000009167.1|UniProtKB=W5MS20 W5MS20 PTHR12825:SF0 BNIP1-RELATED VESICLE TRANSPORT PROTEIN SEC20 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;SNARE complex#GO:0031201;membrane protein complex#GO:0098796;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000016506.1|UniProtKB=W5NID5 W5NID5 PTHR11208:SF42 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING RNA-BINDING PROTEIN QKI RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000002152.1|UniProtKB=W5M2A0 W5M2A0 PTHR43442:SF3 GLUCONOKINASE-RELATED GLUCONOKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;nucleotide metabolic process#GO:0009117;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;pentose-phosphate shunt#GO:0006098;oxoacid metabolic process#GO:0043436;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000012549.1|UniProtKB=W5N494 W5N494 PTHR15941:SF9 MYOZENIN MYOZENIN-2 molecular condensate scaffold activity#GO:0140693;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 muscle cell development#GO:0055001;cellular response to stimulus#GO:0051716;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;skeletal muscle tissue development#GO:0007519;multicellular organismal process#GO:0032501;tissue development#GO:0009888;developmental process#GO:0032502;cellular developmental process#GO:0048869;system process#GO:0003008;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;actomyosin structure organization#GO:0031032;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;muscle organ development#GO:0007517;cellular anatomical entity morphogenesis#GO:0032989;striated muscle tissue development#GO:0014706;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;sarcomere#GO:0030017;membraneless organelle#GO:0043228;I band#GO:0031674;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000009396.1|UniProtKB=W5MSV2 W5MSV2 PTHR13372:SF2 GEMININ GEMININ COILED-COIL DOMAIN-CONTAINING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA replication#GO:0006275;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated DNA replication initiation#GO:0030174;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016103.1|UniProtKB=W5NGT4 W5NGT4 PTHR11339:SF289 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED VWFD DOMAIN-CONTAINING PROTEIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000002060.1|UniProtKB=W5M213 W5M213 PTHR45872:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 12 guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;signaling receptor binding#GO:0005102;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000010561.1|UniProtKB=W5MX41 W5MX41 PTHR13585:SF31 CHASCON, ISOFORM D-RELATED ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13 mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080 LEPOC|Ensembl=ENSLOCG00000004477.1|UniProtKB=W5MAE6 W5MAE6 PTHR45834:SF5 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 13 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;lamellipodium assembly#GO:0030032;cell projection assembly#GO:0030031;filopodium assembly#GO:0046847;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000005767.1|UniProtKB=W5MF10 W5MF10 PTHR13230:SF5 GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;rRNA transcription#GO:0009303;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384 protein-containing complex#GO:0032991;transcription factor TFIIIC complex#GO:0000127;transcription regulator complex#GO:0005667 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000008947.1|UniProtKB=W5MR89 W5MR89 PTHR47085:SF2 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 15 ZINC FINGER MYND-TYPE CONTAINING 15 LEPOC|Ensembl=ENSLOCG00000004696.1|UniProtKB=W5MB66 W5MB66 PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000009045.1|UniProtKB=W5MRL6 W5MRL6 PTHR23052:SF1 AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1 AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017814.1|UniProtKB=W5NMQ9 W5NMQ9 PTHR19290:SF52 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 22 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000016756.1|UniProtKB=W5NJA1 W5NJA1 PTHR23005:SF3 RETINITIS PIGMENTOSA 1 PROTEIN RETINITIS PIGMENTOSA 1-LIKE 1 PROTEIN generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cilium organization#GO:0044782;neuron development#GO:0048666;eye development#GO:0001654;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;neuron differentiation#GO:0030182;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;sensory system development#GO:0048880;cytoskeleton organization#GO:0007010;retina development in camera-type eye#GO:0060041;nervous system development#GO:0007399;cellular component assembly#GO:0022607;anatomical structure homeostasis#GO:0060249;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;camera-type eye development#GO:0043010;system development#GO:0048731;axoneme assembly#GO:0035082;tissue homeostasis#GO:0001894;retina homeostasis#GO:0001895;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;visual system development#GO:0150063;homeostatic process#GO:0042592;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;sensory organ development#GO:0007423;neurogenesis#GO:0022008;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501 ciliary transition zone#GO:0035869;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000004475.1|UniProtKB=W5MAF4 W5MAF4 PTHR10742:SF423 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A protein demethylase activity#GO:0140457;heterocyclic compound binding#GO:1901363;demethylase activity#GO:0032451;histone demethylase activity#GO:0032452;histone modifying activity#GO:0140993;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;chromatin binding#GO:0003682 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000007012.1|UniProtKB=W5MJD0 W5MJD0 PTHR14389:SF15 SI:CH1073-475A24.1 SERINE PROTEASE FAM111A-RELATED catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016438.1|UniProtKB=W5NI44 W5NI44 PTHR46107:SF1 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 4 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000016136.1|UniProtKB=W5NGX5 W5NGX5 PTHR47056:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39 regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000004808.1|UniProtKB=W5MBL2 W5MBL2 PTHR21529:SF4 MAMMARY TURMOR VIRUS RECEPTOR HOMOLOG 1, 2 MTVR1, 2 TPR AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000018025.1|UniProtKB=W5NNB7 W5NNB7 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007432.1|UniProtKB=W5MKV2 W5MKV2 PTHR23068:SF6 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED PWWP DOMAIN-CONTAINING PROTEIN 2B membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 DNA methyltransferase#PC00013 LEPOC|Ensembl=ENSLOCG00000015013.1|UniProtKB=W5NCX3 W5NCX3 PTHR45758:SF4 MITOFERRIN-1-RELATED MITOFERRIN-1 transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;iron ion transmembrane transporter activity#GO:0005381;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;transition metal ion transport#GO:0000041;iron ion transmembrane transport#GO:0034755;iron ion transport#GO:0006826;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000015756.1|UniProtKB=W5NFI8 W5NFI8 PTHR44523:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 13 TETRATRICOPEPTIDE REPEAT PROTEIN 13 LEPOC|Ensembl=ENSLOCG00000014477.1|UniProtKB=W5NB17 W5NB17 PTHR12103:SF19 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING 2 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 phosphatase#PC00181;hydrolase#PC00121;nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000017150.1|UniProtKB=W5NKN5 W5NKN5 PTHR24064:SF186 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 16 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;quaternary ammonium group transmembrane transporter activity#GO:0015651 quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000003312.1|UniProtKB=W5M6A6 W5M6A6 PTHR28656:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 153 DYNEIN REGULATORY COMPLEX PROTEIN 12 LEPOC|Ensembl=ENSLOCG00000001348.1|UniProtKB=W5LZG8 W5LZG8 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006613.1|UniProtKB=W5MHY5 W5MHY5 PTHR10410:SF41 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED MPN DOMAIN-CONTAINING PROTEIN deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000006734.1|UniProtKB=W5MIE1 W5MIE1 PTHR24025:SF1 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-2 small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000001422.1|UniProtKB=W5LZR0 W5LZR0 PTHR14499:SF122 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD7 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017487.1|UniProtKB=W5NLT3 W5NLT3 PTHR24231:SF45 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CYSTEINYL LEUKOTRIENE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006968.1|UniProtKB=W5MJ72 W5MJ72 PTHR46967:SF1 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN,N-TERMINAL SI:DKEY-21A6.5 LEPOC|Ensembl=ENSLOCG00000003328.1|UniProtKB=W5M6D0 W5M6D0 PTHR11430:SF133 LIPOCALIN LIPOCALIN-LIKE PRECURSOR transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014078.1|UniProtKB=W5N9P2 W5N9P2 PTHR28621:SF1 SELENOPROTEIN S SELENOPROTEIN S establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;transport#GO:0006810;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;protein metabolic process#GO:0019538;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;establishment of protein localization#GO:0045184;response to unfolded protein#GO:0006986;protein transport#GO:0015031;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of biological process#GO:0050789 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000007835.1|UniProtKB=W5MMA2 W5MMA2 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001813.1|UniProtKB=W5M132 W5M132 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;immune response#GO:0006955;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;immune system process#GO:0002376 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003296.1|UniProtKB=W5M6F8 W5M6F8 PTHR23175:SF16 PDZ DOMAIN-CONTAINING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 21 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 microtubule-based transport#GO:0099111;organelle localization#GO:0051640;cellular localization#GO:0051641;localization#GO:0051179;Golgi organization#GO:0007030;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;organelle transport along microtubule#GO:0072384;endomembrane system organization#GO:0010256;cytoskeleton-dependent intracellular transport#GO:0030705 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;cell junction#GO:0030054;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008292.1|UniProtKB=W5MNW5 W5MNW5 PTHR22939:SF13 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA1 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;cell death#GO:0008219;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;protein metabolic process#GO:0019538;proteolysis#GO:0006508;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of apoptotic process#GO:0043065;macromolecule metabolic process#GO:0043170;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013817.1|UniProtKB=W5N8S9 W5N8S9 PTHR31395:SF27 SHISA PROTEIN SHISA-5 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014047.1|UniProtKB=W5N9L0 W5N9L0 PTHR11461:SF49 SERINE PROTEASE INHIBITOR, SERPIN PLASMINOGEN ACTIVATOR INHIBITOR 1 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 regulation of vasculature development#GO:1901342;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;negative regulation of blood coagulation#GO:0030195;regulation of response to stimulus#GO:0048583;negative regulation of angiogenesis#GO:0016525;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;negative regulation of wound healing#GO:0061045;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of hemostasis#GO:1900046;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to stimulus#GO:0048585;regulation of coagulation#GO:0050818;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of angiogenesis#GO:0045765;negative regulation of multicellular organismal process#GO:0051241;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;regulation of developmental process#GO:0050793;regulation of proteolysis#GO:0030162;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of response to wounding#GO:1903035;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of response to wounding#GO:1903034;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;positive regulation of coagulation#GO:0050820;negative regulation of hemostasis#GO:1900047;negative regulation of coagulation#GO:0050819;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;regulation of wound healing#GO:0061041;negative regulation of metabolic process#GO:0009892 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>PAI-1#P00411;p53 pathway#P00059>PAI#G04700;Plasminogen activating cascade#P00050>PAI-1#P01245;CCKR signaling map#P06959>PAI1#G07281;CCKR signaling map#P06959>PAI1#G06987 LEPOC|Ensembl=ENSLOCG00000005606.1|UniProtKB=W5MEH5 W5MEH5 PTHR45754:SF3 METHYLENETETRAHYDROFOLATE REDUCTASE METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH) oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;tetrahydrofolate biosynthetic process#GO:0046654;tetrahydrofolate metabolic process#GO:0046653;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;sulfur compound metabolic process#GO:0006790;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000010961.1|UniProtKB=W5MYJ0 W5MYJ0 PTHR11311:SF15 SPONDIN SPONDIN-2 cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000012436.1|UniProtKB=W5N3V3 W5N3V3 PTHR11606:SF13 GLUTAMATE DEHYDROGENASE GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 LEPOC|Ensembl=ENSLOCG00000006453.1|UniProtKB=W5MHD3 W5MHD3 PTHR14882:SF5 COILED-COIL DOMAIN-CONTAINING 74A COILED-COIL DOMAIN CONTAINING 74A LEPOC|Ensembl=ENSLOCG00000001739.1|UniProtKB=W5M0V5 W5M0V5 PTHR10231:SF90 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-SUGAR TRANSPORTER PROTEIN SLC35A5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011720.1|UniProtKB=W5N1A1 W5N1A1 PTHR10337:SF4 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell surface receptor signaling pathway#GO:0007166;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Shc#P01175;FGF signaling pathway#P00021>Shc#P00639;EGF receptor signaling pathway#P00018>Shc#P00554 LEPOC|Ensembl=ENSLOCG00000005170.1|UniProtKB=W5MD76 W5MD76 PTHR13817:SF103 TITIN HEMICENTIN 2 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000012228.1|UniProtKB=W5N335 W5N335 PTHR43880:SF21 ALCOHOL DEHYDROGENASE S-(HYDROXYMETHYL)GLUTATHIONE DEHYDROGENASE ion binding#GO:0043167;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;metal ion binding#GO:0046872;cation binding#GO:0043169;zinc ion binding#GO:0008270;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491 small molecule catabolic process#GO:0044282;response to toxic substance#GO:0009636;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;cellular detoxification of aldehyde#GO:0110095;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;detoxification#GO:0098754;response to chemical#GO:0042221;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;cellular response to oxygen-containing compound#GO:1901701;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000009802.1|UniProtKB=W5MUE6 W5MUE6 PTHR10972:SF200 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9 sterol binding#GO:0032934;binding#GO:0005488;lipid binding#GO:0008289;steroid binding#GO:0005496 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000005851.1|UniProtKB=W5MFA2 W5MFA2 PTHR19343:SF13 T CELL RECEPTOR ALPHA VARIABLE 1-2 IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;peptide binding#GO:0042277;antigen binding#GO:0003823 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015384.1|UniProtKB=W5NE75 W5NE75 PTHR21705:SF9 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 2B LEPOC|Ensembl=ENSLOCG00000010659.1|UniProtKB=W5MXF2 W5MXF2 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012446.1|UniProtKB=W5N3W2 W5N3W2 PTHR13866:SF31 SPARC OSTEONECTIN SPARC-LIKE PROTEIN 1 calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000005309.1|UniProtKB=W5MDE2 W5MDE2 PTHR12411:SF965 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L.1 ISOFORM X1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012301.1|UniProtKB=W5N3C9 W5N3C9 PTHR48051:SF33 FAMILY NOT NAMED LEUCINE-RICH REPEAT PROTEIN SHOC-2 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016647.1|UniProtKB=W5NIV5 W5NIV5 PTHR12027:SF87 WNT RELATED PROTEIN WNT-5B signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cell fate commitment#GO:0045165;system development#GO:0048731;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 LEPOC|Ensembl=ENSLOCG00000015695.1|UniProtKB=W5NFB1 W5NFB1 PTHR22957:SF193 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN USP6 N-TERMINAL-LIKE PROTEIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular process#GO:0009987;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000018239.1|UniProtKB=W5NNY1 W5NNY1 PTHR38325:SF1 MCG55969 GENE, 17455-RELATED LEPOC|Ensembl=ENSLOCG00000015765.1|UniProtKB=W5NFJ9 W5NFJ9 PTHR23170:SF2 NY-REN-58 ANTIGEN CENTROSOMAL PROTEIN OF 83 KDA plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;plasma membrane bounded cell projection assembly#GO:0120031;centrosome localization#GO:0051642;cell projection organization#GO:0030030;establishment of organelle localization#GO:0051656;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;organelle assembly#GO:0070925;organelle localization#GO:0051640 cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cytoskeleton#GO:0005856;centrosome#GO:0005813;Golgi apparatus#GO:0005794;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;ciliary transition fiber#GO:0097539;microtubule cytoskeleton#GO:0015630;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814 LEPOC|Ensembl=ENSLOCG00000006929.1|UniProtKB=W5MJ29 W5MJ29 PTHR11909:SF99 CASEIN KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE VRK3 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;response to stress#GO:0006950;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000003453.1|UniProtKB=W5M6T4 W5M6T4 PTHR47979:SF5 DRAB11-RELATED RAS-RELATED PROTEIN RAB-42 anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000002843.1|UniProtKB=W5M4N8 W5M4N8 PTHR43884:SF42 ACYL-COA DEHYDROGENASE SHORT-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;short-chain fatty acid catabolic process#GO:0019626;fatty acid catabolic process#GO:0009062 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014571.1|UniProtKB=W5NBC6 W5NBC6 PTHR18945:SF907 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-7 ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230 anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;metal ion transport#GO:0030001;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;synaptic transmission, cholinergic#GO:0007271;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell body#GO:0044297;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;axon#GO:0030424;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;presynaptic membrane#GO:0042734;membrane#GO:0016020;neuron projection#GO:0043005;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079 LEPOC|Ensembl=ENSLOCG00000000104.1|UniProtKB=W5LVF6 W5LVF6 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008328.1|UniProtKB=W5MP07 W5MP07 PTHR24208:SF115 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX5 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000000423.1|UniProtKB=W5LWK3 W5LWK3 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000005047.1|UniProtKB=W5MCK4 W5MCK4 PTHR12093:SF9 NCK-ASSOCIATED PROTEIN 1 NCK-ASSOCIATED PROTEIN 1-LIKE cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell migration#GO:0016477;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;anatomical structure development#GO:0048856;cortical actin cytoskeleton organization#GO:0030866;system development#GO:0048731;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000005224.1|UniProtKB=W5MD45 W5MD45 PTHR42840:SF3 NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000011491.1|UniProtKB=W5N0G3 W5N0G3 PTHR12369:SF20 CHONDROITIN SYNTHASE CHONDROITIN SULFATE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194 proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000004375.1|UniProtKB=W5MA14 W5MA14 PTHR24412:SF490 KELCH PROTEIN BTB DOMAIN-CONTAINING PROTEIN enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015943.1|UniProtKB=W5NG72 W5NG72 PTHR43085:SF55 HEXOKINASE FAMILY MEMBER KETOHEXOKINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;regulation of carbohydrate biosynthetic process#GO:0043255;carbohydrate metabolic process#GO:0005975;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;small molecule metabolic process#GO:0044281;regulation of glycogen biosynthetic process#GO:0005979;monosaccharide metabolic process#GO:0005996;regulation of carbohydrate metabolic process#GO:0006109;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065;metabolite interconversion enzyme#PC00262;transferase#PC00220 Fructose galactose metabolism#P02744>Ketohexokinase#P02963 LEPOC|Ensembl=ENSLOCG00000010073.1|UniProtKB=W5MVB1 W5MVB1 PTHR14421:SF3 SPERMATOGENESIS-ASSOCIATED PROTEIN 1 SPERMATOGENESIS-ASSOCIATED PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000015498.1|UniProtKB=W5NEL6 W5NEL6 PTHR13832:SF872 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1G catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000014485.1|UniProtKB=W5NB16 W5NB16 PTHR31666:SF0 PROTEIN CXORF40A-RELATED PROTEIN EOLA1-RELATED LEPOC|Ensembl=ENSLOCG00000017220.1|UniProtKB=W5NKY5 W5NKY5 PTHR11360:SF322 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 10 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;monocarboxylic acid transmembrane transporter activity#GO:0008028 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018265.1|UniProtKB=W5NP07 W5NP07 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015310.1|UniProtKB=W5NDY1 W5NDY1 PTHR48208:SF2 CENTROMERE PROTEIN I CENTROMERE PROTEIN I mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;organelle fission#GO:0048285;kinetochore organization#GO:0051383;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle assembly#GO:0070925;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059 condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776;organelle#GO:0043226;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000007787.1|UniProtKB=W5MM40 W5MM40 PTHR11442:SF7 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT BETA-RELATED tetrapyrrole binding#GO:0046906;molecular carrier activity#GO:0140104;binding#GO:0005488;heme binding#GO:0020037 myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;localization#GO:0051179;cellular process#GO:0009987;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 globin#PC00107;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000009796.1|UniProtKB=W5MUC1 W5MUC1 PTHR11455:SF64 CRYPTOCHROME CRYPTOCHROME DASH nucleoside phosphate binding#GO:1901265;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;ion binding#GO:0043167;nucleic acid binding#GO:0003676;deoxyribodipyrimidine photo-lyase activity#GO:0003904;anion binding#GO:0043168;small molecule binding#GO:0036094;DNA binding#GO:0003677;damaged DNA binding#GO:0003684;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nucleotide binding#GO:0000166 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;photoreactive repair#GO:0000719;pyrimidine dimer repair#GO:0006290;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 DNA photolyase#PC00014 LEPOC|Ensembl=ENSLOCG00000010603.1|UniProtKB=W5MX78 W5MX78 PTHR43818:SF2 BCDNA.GH03377 GLUCOSE-FRUCTOSE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000016694.1|UniProtKB=W5NJ15 W5NJ15 PTHR10265:SF9 CYCLIN-DEPENDENT KINASE INHIBITOR 1 CYCLIN-DEPENDENT KINASE INHIBITOR 1B kinase inhibitor activity#GO:0019210;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle#GO:0045786;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase inhibitor#PC00139;kinase modulator#PC00140 Interleukin signaling pathway#P00036>p27KIP1#P00982 LEPOC|Ensembl=ENSLOCG00000013679.1|UniProtKB=W5N8A3 W5N8A3 PTHR18884:SF128 SEPTIN SI:CH211-282J17.13-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;intracellular protein localization#GO:0008104;cytokinesis#GO:0000910;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cell division#GO:0051301;cellular process#GO:0009987;cell cycle process#GO:0022402 cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000001416.1|UniProtKB=W5LZQ5 W5LZQ5 PTHR11819:SF151 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;localization#GO:0051179;renal absorption#GO:0070293;system process#GO:0003008;transport#GO:0006810;carbohydrate transport#GO:0008643;multicellular organismal process#GO:0032501;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;cellular process#GO:0009987;renal system process#GO:0003014;D-glucose transmembrane transport#GO:1904659 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000011840.1|UniProtKB=W5N1P9 W5N1P9 PTHR32261:SF3 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 2 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016026.1|UniProtKB=W5NGI2 W5NGI2 PTHR11850:SF126 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS1 sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790;head development#GO:0060322;nervous system development#GO:0007399;embryonic pattern specification#GO:0009880;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;angiogenesis#GO:0001525;eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell development#GO:0048468;positive regulation of cell population proliferation#GO:0008284;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;hemopoiesis#GO:0030097;regulation of RNA biosynthetic process#GO:2001141;tube development#GO:0035295;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015293.1|UniProtKB=W5NDV5 W5NDV5 PTHR46343:SF3 HYR DOMAIN-CONTAINING PROTEIN SUSHI REPEAT-CONTAINING PROTEIN SRPX2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of synapse assembly#GO:0051965;positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;regulation of multicellular organismal process#GO:0051239;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of synapse assembly#GO:0051963;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cell-cell adhesion#GO:0098609;regulation of biological quality#GO:0065008;regulation of nervous system development#GO:0051960;regulation of synapse structure or activity#GO:0050803;regulation of cell motility#GO:2000145;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;positive regulation of cellular component organization#GO:0051130;cell adhesion#GO:0007155;regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147 LEPOC|Ensembl=ENSLOCG00000014139.1|UniProtKB=W5N9V6 W5N9V6 PTHR15730:SF8 EXPERIMENTAL AUTOIMMUNE PROSTATITIS ANTIGEN 2-RELATED TRPM8 CHANNEL-ASSOCIATED FACTOR HOMOLOG-RELATED transmembrane transporter binding#GO:0044325;binding#GO:0005488;protein binding#GO:0005515 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000005500.1|UniProtKB=W5ME38 W5ME38 PTHR23236:SF2 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4B binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000004773.1|UniProtKB=W5MBH7 W5MBH7 PTHR23257:SF1005 SERINE-THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000001461.1|UniProtKB=W5LZW3 W5LZW3 PTHR46485:SF2 LIM DOMAIN KINASE 1 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000001836.1|UniProtKB=W5M1E0 W5M1E0 PTHR45861:SF1 DNA POLYMERASE ALPHA CATALYTIC SUBUNIT DNA POLYMERASE ALPHA CATALYTIC SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;DNA-directed DNA polymerase activity#GO:0003887;DNA binding#GO:0003677;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;transferase activity#GO:0016740;single-stranded DNA binding#GO:0003697;DNA replication origin binding#GO:0003688;binding#GO:0005488 DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle lumen#GO:0043233;chromosome#GO:0005694;replisome#GO:0030894;nuclear DNA-directed RNA polymerase complex#GO:0055029;replication fork#GO:0005657;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535 DNA metabolism protein#PC00009 DNA replication#P00017>Pol alpha#P00531 LEPOC|Ensembl=ENSLOCG00000012482.1|UniProtKB=W5N422 W5N422 PTHR23206:SF8 MASK PROTEIN ANKYRIN REPEAT AND KH DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000009731.1|UniProtKB=W5MU24 W5MU24 PTHR10665:SF3 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;Notch signaling pathway#GO:0007219;cell surface receptor signaling pathway#GO:0007166 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Notch signaling pathway#P00045>Su(H)#P01101;Angiogenesis#P00005>CSL#P00233 LEPOC|Ensembl=ENSLOCG00000015181.1|UniProtKB=W5NDH3 W5NDH3 PTHR45727:SF3 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC1-LIKE INTRACELLULAR CHOLESTEROL TRANSPORTER 1 steroid binding#GO:0005496;lipid binding#GO:0008289;cholesterol binding#GO:0015485;alcohol binding#GO:0043178;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094 system process#GO:0003008;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;sterol transport#GO:0015918;localization#GO:0051179;transport#GO:0006810;chemical homeostasis#GO:0048878;lipid localization#GO:0010876;homeostatic process#GO:0042592;multicellular organismal process#GO:0032501;lipid transport#GO:0006869;digestion#GO:0007586;lipid homeostasis#GO:0055088;macromolecule localization#GO:0033036 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000017000.1|UniProtKB=W5NK55 W5NK55 PTHR12876:SF11 N4BP1-RELATED RIBONUCLEASE ZC3H12D-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540 positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;nucleus#GO:0005634 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000002114.1|UniProtKB=W5M247 W5M247 PTHR11576:SF15 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 structural molecule activity#GO:0005198;protein binding#GO:0005515;enzyme binding#GO:0019899;extracellular matrix structural constituent#GO:0005201;binding#GO:0005488 sexual reproduction#GO:0019953;cell recognition#GO:0008037;anatomical structure development#GO:0048856;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;germ cell development#GO:0007281;cell differentiation#GO:0030154;gamete generation#GO:0007276;fertilization#GO:0009566;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;sperm-egg recognition#GO:0035036;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell-cell recognition#GO:0009988;single fertilization#GO:0007338;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;biological regulation#GO:0065007;oogenesis#GO:0048477 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 LEPOC|Ensembl=ENSLOCG00000010858.1|UniProtKB=W5MY53 W5MY53 PTHR15415:SF7 MITOFILIN MICOS COMPLEX SUBUNIT MIC60 LEPOC|Ensembl=ENSLOCG00000008593.1|UniProtKB=W5MPZ3 W5MPZ3 PTHR13462:SF16 CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;cellular process#GO:0009987 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703;transporter complex#GO:1990351;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000008988.1|UniProtKB=W5MRF7 W5MRF7 PTHR11751:SF469 ALANINE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE 2 ISOFORM X1-RELATED transaminase#PC00216;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000008391.1|UniProtKB=W5MP83 W5MP83 PTHR12040:SF8 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1A protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014159.1|UniProtKB=W5N9Y6 W5N9Y6 PTHR11671:SF5 V-TYPE ATP SYNTHASE SUBUNIT D V-TYPE PROTON ATPASE SUBUNIT D monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 vacuolar acidification#GO:0007035;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of intracellular pH#GO:0051453;homeostatic process#GO:0042592;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000007150.1|UniProtKB=W5MJU4 W5MJU4 PTHR46169:SF31 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A SIN3-HDAC COMPLEX-ASSOCIATED FACTOR,-LIKE-RELATED regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011776.1|UniProtKB=W5N1H3 W5N1H3 PTHR48014:SF20 SERINE/THREONINE-PROTEIN KINASE FRAY2 STE20-RELATED KINASE ADAPTER PROTEIN ALPHA kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887 nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein export from nucleus#GO:0006611;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 protein-containing complex#GO:0032991;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000014559.1|UniProtKB=W5NBA7 W5NBA7 PTHR43836:SF10 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE B catalytic activity#GO:0003824;O-methyltransferase activity#GO:0008171;transferase activity#GO:0016740;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 catecholamine metabolic process#GO:0006584;metabolic process#GO:0008152;amine catabolic process#GO:0009310;catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576;amine metabolic process#GO:0009308;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000002834.1|UniProtKB=W5M4M1 W5M4M1 PTHR10458:SF2 PEPTIDE DEFORMYLASE PEPTIDE DEFORMYLASE, MITOCHONDRIAL cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013791.1|UniProtKB=W5N8Q4 W5N8Q4 PTHR13817:SF95 TITIN IMMUNOGLOBULIN SUPERFAMILY DCC SUBCLASS MEMBER 4 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010042.1|UniProtKB=W5MV71 W5MV71 PTHR12832:SF14 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11 HOMOLOG regulation of cell differentiation#GO:0045595;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of cell development#GO:0060284;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of reproductive process#GO:2000241;regulation of multicellular organismal process#GO:0051239;signaling#GO:0023052;biological regulation#GO:0065007;regulation of developmental process#GO:0050793 cytoplasm#GO:0005737;sperm flagellum#GO:0036126;endomembrane system#GO:0012505;secretory vesicle#GO:0099503;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000000207.1|UniProtKB=W5LVS3 W5LVS3 PTHR46780:SF21 PROTEIN EVA-1 D-GALACTOSIDE-SPECIFIC LECTIN ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000005389.1|UniProtKB=W5MDN8 W5MDN8 PTHR13299:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX16 PEROXISOMAL MEMBRANE PROTEIN PEX16 organelle organization#GO:0006996;cellular component organization#GO:0016043;peroxisome organization#GO:0007031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840 peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010530.1|UniProtKB=W5MX00 W5MX00 PTHR13778:SF3 GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000002291.1|UniProtKB=W5M2S0 W5M2S0 PTHR11537:SF167 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL REGULATORY SUBUNIT KCNG4 channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106 transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;action potential#GO:0001508;metal ion transport#GO:0030001 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000004191.1|UniProtKB=W5M9G0 W5M9G0 PTHR21508:SF4 MITOGUARDIN MITOGUARDIN 2 cellular process#GO:0009987;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;organelle fusion#GO:0048284 LEPOC|Ensembl=ENSLOCG00000000221.1|UniProtKB=W5LVT8 W5LVT8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010166.1|UniProtKB=W5MVP1 W5MVP1 PTHR23255:SF63 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-2 transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;transforming growth factor beta receptor activity#GO:0005024;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;blood vessel development#GO:0001568;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;vasculature development#GO:0001944;multicellular organism development#GO:0007275 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740 LEPOC|Ensembl=ENSLOCG00000014872.1|UniProtKB=W5NCF7 W5NCF7 PTHR10224:SF11 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL SI:CH211-153B23.5 LEPOC|Ensembl=ENSLOCG00000007086.1|UniProtKB=W5MJM1 W5MJM1 PTHR25466:SF4 T-LYMPHOCYTE ACTIVATION ANTIGEN T-LYMPHOCYTE ACTIVATION ANTIGEN CD80 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>B7#P01337 LEPOC|Ensembl=ENSLOCG00000005388.1|UniProtKB=W5MDN9 W5MDN9 PTHR45616:SF9 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 8-RELATED structural molecule activity#GO:0005198 cell differentiation#GO:0030154;intermediate filament cytoskeleton organization#GO:0045104;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;intermediate filament organization#GO:0045109;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament-based process#GO:0045103;skin development#GO:0043588;cytoskeleton organization#GO:0007010;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;epithelium development#GO:0060429;cellular process#GO:0009987;organelle organization#GO:0006996;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;epidermis development#GO:0008544 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000008337.1|UniProtKB=W5MP19 W5MP19 PTHR42874:SF1 URICASE URICASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;purine-containing compound catabolic process#GO:0072523;purine nucleobase catabolic process#GO:0006145;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000017520.1|UniProtKB=W5NLW6 W5NLW6 PTHR11984:SF5 CONNEXIN GAP JUNCTION DELTA-3 PROTEIN passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000008091.1|UniProtKB=W5MN74 W5MN74 PTHR26451:SF854 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017811.1|UniProtKB=W5NMQ6 W5NMQ6 PTHR14388:SF18 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SUPPRESSOR OF CYTOKINE SIGNALING 6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001964.1|UniProtKB=W5M1L4 W5M1L4 PTHR24233:SF10 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 13 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007923.1|UniProtKB=W5MML6 W5MML6 PTHR24390:SF83 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002369.1|UniProtKB=W5M324 W5M324 PTHR44783:SF1 CXADR-LIKE MEMBRANE PROTEIN CXADR-LIKE MEMBRANE PROTEIN LEPOC|Ensembl=ENSLOCG00000010350.1|UniProtKB=W5MWC6 W5MWC6 PTHR36473:SF1 CHROMOSOME 3 OPEN READING FRAME 49 GENE 11100-RELATED LEPOC|Ensembl=ENSLOCG00000008910.1|UniProtKB=W5MR49 W5MR49 PTHR22770:SF45 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED RANBP-TYPE AND C3HC4-TYPE ZINC FINGER-CONTAINING PROTEIN 1-RELATED acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 proteasomal protein catabolic process#GO:0010498;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000006873.1|UniProtKB=W5MIV4 W5MIV4 PTHR43917:SF9 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE THETA-1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007731.1|UniProtKB=W5MLX8 W5MLX8 PTHR22142:SF2 KINETOCHORE PROTEIN SPC24 KINETOCHORE PROTEIN SPC24 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cellular process#GO:0009987;cell cycle process#GO:0022402;chromosome segregation#GO:0007059;cell cycle#GO:0007049 organelle#GO:0043226;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012980.1|UniProtKB=W5N5S8 W5N5S8 PTHR14096:SF59 APOLIPOPROTEIN L APOLIPOPROTEIN L1 ISOFORM X1 lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical structure#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000012353.1|UniProtKB=W5N3K3 W5N3K3 PTHR11359:SF3 AMP DEAMINASE AMP DEAMINASE 2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814 organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;IMP metabolic process#GO:0046040;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693 deaminase#PC00088 LEPOC|Ensembl=ENSLOCG00000004551.1|UniProtKB=W5MAN4 W5MAN4 PTHR45682:SF6 AGAP008228-PA DUAL SPECIFICITY PHOSPHATASE 29 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000000439.1|UniProtKB=W5LWH2 W5LWH2 PTHR19433:SF111 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 4 response to stimulus#GO:0050896;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007782.1|UniProtKB=W5MM38 W5MM38 PTHR10529:SF234 AP COMPLEX SUBUNIT MU AP-1 COMPLEX SUBUNIT MU-2 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;cellular localization#GO:0051641;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 membrane protein complex#GO:0098796;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;clathrin-coated vesicle#GO:0030136;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular organelle#GO:0043229;coated membrane#GO:0048475;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;vesicle coat#GO:0030120;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009052.1|UniProtKB=W5MRM2 W5MRM2 PTHR19972:SF15 CALBINDIN SECRETAGOGIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection terminus#GO:0044306;cell projection#GO:0042995;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;axon terminus#GO:0043679;cytosol#GO:0005829;presynapse#GO:0098793;neuron projection#GO:0043005;nucleus#GO:0005634;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000004402.1|UniProtKB=W5MA50 W5MA50 PTHR11783:SF212 SULFOTRANSFERASE SULT SULFOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000013955.1|UniProtKB=W5N990 W5N990 PTHR46456:SF2 DNA REPAIR PROTEIN RAD51 HOMOLOG 2 DNA REPAIR PROTEIN RAD51 HOMOLOG 2 catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;four-way junction DNA binding#GO:0000400;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;replication fork#GO:0005657;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002945.1|UniProtKB=W5M507 W5M507 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000008625.1|UniProtKB=W5MQ27 W5MQ27 PTHR11818:SF19 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A4 structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;sensory system development#GO:0048880;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception of light stimulus#GO:0050953;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006651.1|UniProtKB=W5MI22 W5MI22 PTHR10333:SF41 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 5 chromatin-protein adaptor activity#GO:0140463;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090;chromatin binding#GO:0003682;histone reader activity#GO:0140566 regulation of apoptotic process#GO:0042981;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;positive regulation of programmed cell death#GO:0043068;regulation of response to stimulus#GO:0048583;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;regulation of apoptotic signaling pathway#GO:2001233;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of signal transduction#GO:0009967;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010600.1|UniProtKB=W5MX73 W5MX73 PTHR24028:SF9 CADHERIN-87A PROTOCADHERIN-18 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000013121.1|UniProtKB=W5N6A6 W5N6A6 PTHR23077:SF117 AAA-FAMILY ATPASE ATPASE FAMILY GENE 2 PROTEIN HOMOLOG B pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010247.1|UniProtKB=W5MVY8 W5MVY8 PTHR23504:SF32 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 SOLUTE CARRIER FAMILY 71 MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014783.1|UniProtKB=W5NC43 W5NC43 PTHR14633:SF3 LITTLE ELONGATION COMPLEX SUBUNIT 2 LITTLE ELONGATION COMPLEX SUBUNIT 2 positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;transcription by RNA polymerase II#GO:0006366;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;regulation of DNA-templated transcription#GO:0006355;snRNA transcription by RNA polymerase III#GO:0042796;snRNA metabolic process#GO:0016073;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;snRNA transcription#GO:0009301;transcription by RNA polymerase III#GO:0006383;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;nucleic acid biosynthetic process#GO:0141187 LEPOC|Ensembl=ENSLOCG00000009629.1|UniProtKB=W5MTR3 W5MTR3 PTHR43389:SF5 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B, BRAIN ISOFORM monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;proton transmembrane transport#GO:1902600;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453 ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cation-transporting ATPase complex#GO:0090533;apical plasma membrane#GO:0016324;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;apical part of cell#GO:0045177;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068;ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000012488.1|UniProtKB=W5N434 W5N434 PTHR11616:SF249 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;amino acid transport#GO:0006865;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000008451.1|UniProtKB=W5MPH2 W5MPH2 PTHR12636:SF5 NEP1/MRA1 RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1 RNA binding#GO:0003723;catalytic activity, acting on a rRNA#GO:0140102;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;rRNA binding#GO:0019843;transferase activity#GO:0016740 rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;rRNA base methylation#GO:0070475;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040 transferase#PC00220;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000015136.1|UniProtKB=W5NDB8 W5NDB8 PTHR21734:SF11 INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN LEPOC|Ensembl=ENSLOCG00000005376.1|UniProtKB=W5MDM0 W5MDM0 PTHR13483:SF3 BOX C_D SNORNA PROTEIN 1-RELATED BOX C_D SNORNA PROTEIN 1 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000014475.1|UniProtKB=W5NB09 W5NB09 PTHR13117:SF5 ENDOPLASMIC RETICULUM MULTISPAN TRANSMEMBRANE PROTEIN-RELATED MAN(5)GLCNAC(2)-PP-DOLICHOL TRANSLOCATION PROTEIN RFT1 membrane organization#GO:0061024;lipid translocation#GO:0034204;biological regulation#GO:0065007;lipid transport#GO:0006869;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007288.1|UniProtKB=W5MKB5 W5MKB5 PTHR43243:SF17 INNER MEMBRANE TRANSPORTER YGJI-RELATED SOLUTE CARRIER FAMILY 7 MEMBER 14 amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 amino acid transport#GO:0006865;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 amino acid transporter#PC00046;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000004687.1|UniProtKB=W5MB81 W5MB81 PTHR10509:SF14 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000007366.1|UniProtKB=W5MKM9 W5MKM9 PTHR11902:SF10 ENOLASE GAMMA-ENOLASE catalytic activity#GO:0003824;phosphopyruvate hydratase activity#GO:0004634;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;nicotinamide nucleotide metabolic process#GO:0046496;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281 catalytic complex#GO:1902494;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 lyase#PC00144;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Enolase#P00678 LEPOC|Ensembl=ENSLOCG00000015493.1|UniProtKB=W5NEK8 W5NEK8 PTHR24044:SF380 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;negative regulation of Notch signaling pathway#GO:0045746;negative regulation of cellular process#GO:0048523;Notch signaling pathway#GO:0007219 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 LEPOC|Ensembl=ENSLOCG00000008443.1|UniProtKB=W5MPF5 W5MPF5 PTHR14619:SF9 NEURON-DERIVED NEUROTROPHIC FACTOR PROTEIN NDNF heparin binding#GO:0008201;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539 LEPOC|Ensembl=ENSLOCG00000003276.1|UniProtKB=W5M657 W5M657 PTHR43296:SF12 PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING] catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000004532.1|UniProtKB=W5MAL2 W5MAL2 PTHR10411:SF3 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 ALPHA molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;regulation of JNK cascade#GO:0046328;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 p53 pathway#P00059>GADD45#G01575;PI3 kinase pathway#P00048>GADD45#G01544;p38 MAPK pathway#P05918>GADD45#P06044;p53 pathway#P00059>GADD45#P04626 LEPOC|Ensembl=ENSLOCG00000013088.1|UniProtKB=W5N665 W5N665 PTHR45869:SF7 C-REACTIVE PROTEIN-RELATED PENTRAXIN FAMILY MEMBER LEPOC|Ensembl=ENSLOCG00000003691.1|UniProtKB=W5M7U1 W5M7U1 PTHR10807:SF4 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 13 guanyl-nucleotide exchange factor activity#GO:0005085;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;phosphoric ester hydrolase activity#GO:0042578;molecular function regulator activity#GO:0098772 phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;dephosphorylation#GO:0016311;lipid modification#GO:0030258;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000016690.1|UniProtKB=W5NJ11 W5NJ11 PTHR46876:SF1 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LEPOC|Ensembl=ENSLOCG00000009437.1|UniProtKB=W5MT08 W5MT08 PTHR11955:SF69 FATTY ACID BINDING PROTEIN GASTROTROPIN lipid binding#GO:0008289;fatty acid binding#GO:0005504;organic acid binding#GO:0043177;ion binding#GO:0043167;carboxylic acid binding#GO:0031406;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;establishment of localization#GO:0051234;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000010903.1|UniProtKB=W5MYA8 W5MYA8 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010741.1|UniProtKB=W5MXP7 W5MXP7 PTHR36466:SF2 BCL-2-LIKE PROTEIN 15 BCL2 LIKE 15 LEPOC|Ensembl=ENSLOCG00000006948.1|UniProtKB=W5MJ53 W5MJ53 PTHR10836:SF111 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891 purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676 LEPOC|Ensembl=ENSLOCG00000005831.1|UniProtKB=W5MFB3 W5MFB3 PTHR21610:SF9 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010401.1|UniProtKB=W5MWJ1 W5MWJ1 PTHR28651:SF1 TRANSMEMBRANE PROTEIN 232 TRANSMEMBRANE PROTEIN 232 LEPOC|Ensembl=ENSLOCG00000008603.1|UniProtKB=W5MPZ9 W5MPZ9 PTHR21564:SF4 BRAKELESS PROTEIN ZINC FINGER PROTEIN 608 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000006913.1|UniProtKB=W5MJ02 W5MJ02 PTHR15185:SF5 BCL9 B-CELL CLL_LYMPHOMA 9 PROTEIN binding#GO:0005488;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;canonical Wnt signaling pathway#GO:0060070;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 Wnt signaling pathway#P00057>Bcl9#P01450 LEPOC|Ensembl=ENSLOCG00000018040.1|UniProtKB=W5NND2 W5NND2 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000015046.1|UniProtKB=W5ND10 W5ND10 PTHR11636:SF80 POU DOMAIN HIGHLY DIVERGENT HOMEOBOX transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000010673.1|UniProtKB=W5MXH4 W5MXH4 PTHR23255:SF61 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-1 molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;activin binding#GO:0048185;transforming growth factor beta receptor activity#GO:0005024 transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;signal transduction#GO:0007165;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;animal organ development#GO:0048513;multicellular organism development#GO:0007275;endothelial cell proliferation#GO:0001935;epithelial cell proliferation#GO:0050673;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;activin receptor signaling pathway#GO:0032924;cellular response to growth factor stimulus#GO:0071363;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to transforming growth factor beta#GO:0071559;cell population proliferation#GO:0008283;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731 membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695;signaling receptor complex#GO:0043235;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 LEPOC|Ensembl=ENSLOCG00000016575.1|UniProtKB=W5NIL7 W5NIL7 PTHR11818:SF2 BETA/GAMMA CRYSTALLIN BETA_GAMMA CRYSTALLIN DOMAIN-CONTAINING PROTEIN 1 structural molecule activity#GO:0005198 nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sensory system development#GO:0048880;multicellular organismal process#GO:0032501 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008480.1|UniProtKB=W5MPL1 W5MPL1 PTHR11003:SF32 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 10 potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843 cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016718.1|UniProtKB=W5NJ45 W5NJ45 PTHR24113:SF12 RAN GTPASE-ACTIVATING PROTEIN 1 RAN GTPASE-ACTIVATING PROTEIN 1 enzyme binding#GO:0019899;binding#GO:0005488;molecular function activator activity#GO:0140677;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nuclear transport#GO:0051169;nuclear export#GO:0051168;intracellular transport#GO:0046907;transport#GO:0006810;nucleocytoplasmic transport#GO:0006913 perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013740.1|UniProtKB=W5N8I9 W5N8I9 PTHR48105:SF37 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN-DISULFIDE REDUCTASE (NADPH) antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725 mitochondrion#GO:0005739;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017751.1|UniProtKB=W5NMJ6 W5NMJ6 PTHR28613:SF7 SI:CH211-232M10.4-RELATED TRANSMEMBRANE PROTEIN 238-LIKE LEPOC|Ensembl=ENSLOCG00000015773.1|UniProtKB=W5NFK8 W5NFK8 PTHR10155:SF7 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 2 cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;negative regulation of cellular process#GO:0048523;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;response to cytokine#GO:0034097;response to chemical#GO:0042221;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;cytokine-mediated signaling pathway#GO:0019221;negative regulation of signaling#GO:0023057;response to peptide#GO:1901652;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 LEPOC|Ensembl=ENSLOCG00000017193.1|UniProtKB=W5NKU0 W5NKU0 PTHR24020:SF12 COLLAGEN ALPHA MATRILIN-3 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000010413.1|UniProtKB=W5MWM2 W5MWM2 PTHR12913:SF1 UNR PROTEIN N-RAS UPSTREAM GENE PROTEIN COLD SHOCK DOMAIN-CONTAINING PROTEIN E1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517 positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;RNA stabilization#GO:0043489;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000016249.1|UniProtKB=W5NHD0 W5NHD0 PTHR11473:SF16 AROMATIC AMINO ACID HYDROXYLASE TRYPTOPHAN 5-HYDROXYLASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 phenol-containing compound biosynthetic process#GO:0046189;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;serotonin biosynthetic process#GO:0042427;biosynthetic process#GO:0009058;metabolic process#GO:0008152;serotonin metabolic process#GO:0042428 neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 5-Hydroxytryptamine biosynthesis#P04371>Tryptophan hydroxylase#P04399 LEPOC|Ensembl=ENSLOCG00000001467.1|UniProtKB=W5LZX2 W5LZX2 PTHR21496:SF0 FERREDOXIN-RELATED RIESKE DOMAIN-CONTAINING PROTEIN small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010989.1|UniProtKB=W5MYL8 W5MYL8 PTHR14089:SF6 PRE-MRNA-SPLICING FACTOR RBM22 PRE-MRNA-SPLICING FACTOR RBM22 binding#GO:0005488;pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069 catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009778.1|UniProtKB=W5MU89 W5MU89 PTHR24377:SF1028 IP01015P-RELATED ZINC FINGER PROTEIN 84 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013487.1|UniProtKB=W5N7L8 W5N7L8 PTHR15416:SF2 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 kinase inhibitor#PC00139;kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000018238.1|UniProtKB=W5NNY0 W5NNY0 PTHR21011:SF17 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000016998.1|UniProtKB=W5NK53 W5NK53 PTHR46253:SF2 TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 2 protein binding#GO:0005515;modification-dependent protein binding#GO:0140030;binding#GO:0005488;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;polyubiquitin modification-dependent protein binding#GO:0031593 regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;positive regulation of signaling#GO:0023056;anatomical structure development#GO:0048856;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;heart development#GO:0007507;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;animal organ development#GO:0048513;multicellular organism development#GO:0007275 p38 MAPK pathway#P05918>TAB2#P06033 LEPOC|Ensembl=ENSLOCG00000007583.1|UniProtKB=W5MLE5 W5MLE5 PTHR12474:SF4 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-3 catalytic activity#GO:0003824;amino acid binding#GO:0016597;oxidoreductase activity#GO:0016491;organic acid binding#GO:0043177;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;cation binding#GO:0043169 response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;positive regulation of macroautophagy#GO:0016239;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to amino acid starvation#GO:0034198;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;regulation of macroautophagy#GO:0016241;negative regulation of TORC1 signaling#GO:1904262;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000017198.1|UniProtKB=W5NKV2 W5NKV2 PTHR10742:SF342 FLAVIN MONOAMINE OXIDASE L-AMINO-ACID OXIDASE ISOFORM X1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 oxidase#PC00175 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 LEPOC|Ensembl=ENSLOCG00000012814.1|UniProtKB=W5N557 W5N557 PTHR13080:SF16 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE F(0) COMPLEX SUBUNIT F, MITOCHONDRIAL proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252 nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521 respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000002185.1|UniProtKB=W5M2D8 W5M2D8 PTHR23039:SF6 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000007016.1|UniProtKB=W5MJE1 W5MJE1 PTHR10658:SF28 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN ALPHA ISOFORM anion binding#GO:0043168;small molecule binding#GO:0036094;lipid carrier activity#GO:0005319;phosphatidylcholine intramembrane carrier activity#GO:0008525;ion binding#GO:0043167;intramembrane lipid carrier activity#GO:0140303;cation binding#GO:0043169;phospholipid binding#GO:0005543;phosphatidylinositol binding#GO:0035091;phosphatidylcholine binding#GO:0031210;phosphatidylinositol transfer activity#GO:0008526;binding#GO:0005488;molecular carrier activity#GO:0140104;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;transporter activity#GO:0005215 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010172.1|UniProtKB=W5MVN6 W5MVN6 PTHR12015:SF217 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE-RELATED cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000002807.1|UniProtKB=W5M4J4 W5M4J4 PTHR13594:SF3 CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA ISOFORM X1 cell projection organization#GO:0030030;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;organelle assembly#GO:0070925;centriole replication#GO:0007099;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000002289.1|UniProtKB=W5M2S3 W5M2S3 PTHR46047:SF2 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;phosphoprotein phosphatase activity#GO:0004721;protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;regulation of response to endoplasmic reticulum stress#GO:1905897;negative regulation of biological process#GO:0048519;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cellular response to stress#GO:0080135;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of response to stimulus#GO:0048585;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134 intracellular organelle#GO:0043229;endosome#GO:0005768;endoplasmic reticulum#GO:0005783;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Cadherin signaling pathway#P00012>Tyrosine phosphatases#P00472 LEPOC|Ensembl=ENSLOCG00000007395.1|UniProtKB=W5MKR6 W5MKR6 PTHR24340:SF21 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-6.2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009461.1|UniProtKB=W5MT44 W5MT44 PTHR11129:SF3 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000012860.1|UniProtKB=W5N5D4 W5N5D4 PTHR10336:SF10 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-2 phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787;lipase activity#GO:0016298 calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;metabolic process#GO:0008152;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;signal transduction#GO:0007165;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;establishment of localization#GO:0051234;transport#GO:0006810;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;organophosphate metabolic process#GO:0019637;intracellular signal transduction#GO:0035556;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143 Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Wnt signaling pathway#P00057>Phospholipase C#P01443;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Endogenous cannabinoid signaling#P05730>PLC#P05746;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Endothelin signaling pathway#P00019>PLCbeta#P00591;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744 LEPOC|Ensembl=ENSLOCG00000018061.1|UniProtKB=W5NNF3 W5NNF3 PTHR24228:SF9 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR C-X-C CHEMOKINE RECEPTOR GPR25 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009846.1|UniProtKB=W5MUH3 W5MUH3 PTHR31220:SF3 HYCCIN RELATED HYCCIN 2 protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphatidylinositol phosphate biosynthetic process#GO:0046854;localization within membrane#GO:0051668;localization#GO:0051179;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;protein localization to cell periphery#GO:1990778;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;intracellular protein localization#GO:0008104 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015914.1|UniProtKB=W5NG37 W5NG37 PTHR22878:SF64 DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED DYNEIN AXONEMAL HEAVY CHAIN 14 LEPOC|Ensembl=ENSLOCG00000009380.1|UniProtKB=W5MST4 W5MST4 PTHR24247:SF211 5-HYDROXYTRYPTAMINE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011352.1|UniProtKB=W5MZZ6 W5MZZ6 PTHR22855:SF13 ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005803.1|UniProtKB=W5MF51 W5MF51 PTHR23113:SF35 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 Ras Pathway#P04393>RalGDS#P04551 LEPOC|Ensembl=ENSLOCG00000002175.1|UniProtKB=W5M2C3 W5M2C3 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007495.1|UniProtKB=W5ML55 W5ML55 PTHR23113:SF175 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000009037.1|UniProtKB=W5MRK8 W5MRK8 PTHR13471:SF0 TETRATRICOPEPTIDE-LIKE HELICAL NUCLEAR EXOSOME REGULATOR NRDE2 negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892 LEPOC|Ensembl=ENSLOCG00000014063.1|UniProtKB=W5N9M0 W5N9M0 PTHR47403:SF3 LOC100145250 PROTEIN N-ACETYLTRANSFERASE 16-RELATED LEPOC|Ensembl=ENSLOCG00000015497.1|UniProtKB=W5NEL4 W5NEL4 PTHR11371:SF11 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;DNA binding#GO:0003677;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000004133.1|UniProtKB=W5M979 W5M979 PTHR33962:SF1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 RMI2 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 response to stress#GO:0006950;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;regulation of chromosome organization#GO:0033044;DNA damage response#GO:0006974;regulation of chromosome segregation#GO:0051983;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;cellular response to stress#GO:0033554 intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear speck#GO:0016607;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000016214.1|UniProtKB=W5NH85 W5NH85 PTHR12029:SF11 RNA METHYLTRANSFERASE TRNA (GUANOSINE(18)-2'-O)-METHYLTRANSFERASE TARBP1 tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA methylation#GO:0001510;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002870.1|UniProtKB=W5M4R1 W5M4R1 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED LEPOC|Ensembl=ENSLOCG00000003649.1|UniProtKB=W5M7H8 W5M7H8 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006455.1|UniProtKB=W5MHD4 W5MHD4 PTHR15854:SF4 THAP4 PROTEIN PEROXYNITRITE ISOMERASE THAP4 LEPOC|Ensembl=ENSLOCG00000010510.1|UniProtKB=W5MWX5 W5MWX5 PTHR10155:SF3 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to oxygen-containing compound#GO:1901700 extrinsic component of membrane#GO:0019898;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020 kinase modulator#PC00140 CCKR signaling map#P06959>p85#P07212;T cell activation#P00053>PI3K#P01322;p53 pathway feedback loops 2#P04398>PI3K#P04661;Integrin signalling pathway#P00034>PI3K#P00936;VEGF signaling pathway#P00056>PI3K#P01413;Gonadotropin-releasing hormone receptor pathway#P06664>PI3K#P06766;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;PI3 kinase pathway#P00048>p85#P01202;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;PDGF signaling pathway#P00047>PI3K#P01168 LEPOC|Ensembl=ENSLOCG00000008559.1|UniProtKB=W5MPU9 W5MPU9 PTHR13135:SF0 CYTOSOLIC RESINIFERATOXIN BINDING PROTEIN RBP-26 PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010647.1|UniProtKB=W5MXC8 W5MXC8 PTHR14491:SF2 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHA Ubiquitin proteasome pathway#P00060>E2#P01491 LEPOC|Ensembl=ENSLOCG00000008096.1|UniProtKB=W5MN79 W5MN79 PTHR11384:SF62 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 3 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carboxylic acid transmembrane transporter activity#GO:0046943;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;monocarboxylic acid transmembrane transporter activity#GO:0008028;nucleotide binding#GO:0000166;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857 intracellular transport#GO:0046907;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;transport#GO:0006810;lipid modification#GO:0030258;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;carboxylic acid catabolic process#GO:0046395;lipid transport#GO:0006869;monocarboxylic acid catabolic process#GO:0072329;localization#GO:0051179;fatty acid transport#GO:0015908;lipid oxidation#GO:0034440;monocarboxylic acid transport#GO:0015718;peroxisomal transport#GO:0043574;primary metabolic process#GO:0044238;catabolic process#GO:0009056;carboxylic acid transmembrane transport#GO:1905039;metabolic process#GO:0008152;fatty acid oxidation#GO:0019395;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;lipid catabolic process#GO:0016042;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;peroxisome organization#GO:0007031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;cellular component organization#GO:0016043;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282 membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000003023.1|UniProtKB=W5M5A1 W5M5A1 PTHR13809:SF6 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-10 ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494 heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Enkephalin release#P05913>G-Protein (s)#P05977;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (i)#P05974;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Wnt signaling pathway#P00057>Ggamma#P01465;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002 LEPOC|Ensembl=ENSLOCG00000010202.1|UniProtKB=W5MVT4 W5MVT4 PTHR24072:SF17 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOJ pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515 transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;actin filament organization#GO:0007015;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;cell communication#GO:0007154;localization#GO:0051179;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507;EGF receptor signaling pathway#P00018>Rac#P00564 LEPOC|Ensembl=ENSLOCG00000009677.1|UniProtKB=W5MTW3 W5MTW3 PTHR10686:SF44 FOLATE TRANSPORTER SOLUTE CARRIER FAMILY 19 MEMBER 3A cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011285.1|UniProtKB=W5MZR3 W5MZR3 PTHR18919:SF175 ACETYL-COA C-ACYLTRANSFERASE 3-KETOACYL-COA THIOLASE, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000017705.1|UniProtKB=W5NMF1 W5NMF1 PTHR11711:SF480 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 6 GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;regulation of biological process#GO:0050789;protein localization to organelle#GO:0033365;regulation of developmental process#GO:0050793 ruffle#GO:0001726;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;recycling endosome#GO:0055037;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf6#P00919 LEPOC|Ensembl=ENSLOCG00000012434.1|UniProtKB=W5N3U6 W5N3U6 PTHR10361:SF40 SODIUM-BILE ACID COTRANSPORTER HEPATIC SODIUM_BILE ACID COTRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;bile acid transmembrane transporter activity#GO:0015125;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;localization#GO:0051179;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;lipid transport#GO:0006869 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000014290.1|UniProtKB=W5NAD2 W5NAD2 PTHR15454:SF47 NISCHARIN RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 23 ISOFORM X1 flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;microtubule bundle formation#GO:0001578;cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003;sperm motility#GO:0097722;cell projection organization#GO:0030030;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012856.1|UniProtKB=W5N5C3 W5N5C3 PTHR12442:SF7 DYNEIN INTERMEDIATE CHAIN DYNEIN AXONEMAL INTERMEDIATE CHAIN 2 binding#GO:0005488;protein binding#GO:0005515 protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;cilium movement#GO:0003341;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cilium assembly#GO:0060271 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;outer dynein arm#GO:0036157;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axonemal dynein complex#GO:0005858;dynein complex#GO:0030286 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000017845.1|UniProtKB=W5NMT9 W5NMT9 PTHR24230:SF123 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010565.1|UniProtKB=W5MX34 W5MX34 PTHR12439:SF32 PLACENTAL PROTEIN 11-RELATED URIDYLATE-SPECIFIC ENDORIBONUCLEASE B catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 LEPOC|Ensembl=ENSLOCG00000018261.1|UniProtKB=W5NP03 W5NP03 PTHR22650:SF6 GLYCOPROTEIN IB BETA PLATELET GLYCOPROTEIN IX Blood coagulation#P00011>GP IX#P00455 LEPOC|Ensembl=ENSLOCG00000016974.1|UniProtKB=W5NK22 W5NK22 PTHR31581:SF1 KICSTOR COMPLEX PROTEIN C12ORF66 KICSTOR SUBUNIT 2 localization#GO:0051179;protein localization to vacuole#GO:0072665;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;intracellular protein localization#GO:0008104;regulation of TORC1 signaling#GO:1903432;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;response to nutrient levels#GO:0031667;macromolecule localization#GO:0033036;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;protein localization to lysosome#GO:0061462;negative regulation of TORC1 signaling#GO:1904262;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to stress#GO:0006950 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000005279.1|UniProtKB=W5MDD0 W5MDD0 PTHR16220:SF1 WD REPEAT PROTEIN 8-RELATED WD REPEAT-CONTAINING PROTEIN WRAP73 mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;mitotic spindle assembly#GO:0090307;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007173.1|UniProtKB=W5MJX1 W5MJX1 PTHR11848:SF144 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 3 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000016193.1|UniProtKB=W5NH53 W5NH53 PTHR18919:SF107 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000006083.1|UniProtKB=W5MG44 W5MG44 PTHR11952:SF6 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLHEXOSAMINE PYROPHOSPHORYLASE-LIKE PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleotide-sugar metabolic process#GO:0009225;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006919.1|UniProtKB=W5MJ15 W5MJ15 PTHR10048:SF35 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;organophosphate metabolic process#GO:0019637;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;cell motility#GO:0048870;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 kinase#PC00137 Integrin signalling pathway#P00034>PI3K#P00936;Axon guidance mediated by netrin#P00009>PI3K#P00363;p53 pathway feedback loops 2#P04398>PI3K#P04661;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823;PDGF signaling pathway#P00047>PI3K#P01168;Ras Pathway#P04393>PI3K#P04567;Apoptosis signaling pathway#P00006>PI3K#P00310;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;VEGF signaling pathway#P00056>PI3K#P01413;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;T cell activation#P00053>PI3K#P01322;FGF signaling pathway#P00021>PI3K#P00640;B cell activation#P00010>PI3K#P00391;EGF receptor signaling pathway#P00018>PI3K#P00557;Angiogenesis#P00005>PI3K#P00236 LEPOC|Ensembl=ENSLOCG00000012786.1|UniProtKB=W5N526 W5N526 PTHR15135:SF5 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN 2 molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 regulation of cellular process#GO:0050794;striated muscle contraction#GO:0006941;skeletal muscle contraction#GO:0003009;regulation of biological process#GO:0050789;muscle system process#GO:0003012;regulation of protein localization#GO:0032880;nervous system process#GO:0050877;neuromuscular process#GO:0050905;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of protein localization to membrane#GO:1905475;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;system process#GO:0003008;regulation of localization#GO:0032879;muscle contraction#GO:0006936 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562 LEPOC|Ensembl=ENSLOCG00000003114.1|UniProtKB=W5M5L7 W5M5L7 PTHR24099:SF8 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FSD1-LIKE PROTEIN ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000002598.1|UniProtKB=W5M3U6 W5M3U6 PTHR46724:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000015823.1|UniProtKB=W5NFR9 W5NFR9 PTHR32289:SF3 PROTEIN FAM167A PROTEIN FAM167A LEPOC|Ensembl=ENSLOCG00000001725.1|UniProtKB=W5M0T2 W5M0T2 PTHR46963:SF3 SIMILAR TO RIKEN CDNA E130308A19 ZMYM2-LIKE_QRICH1 C-TERMINAL DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015446.1|UniProtKB=W5NEF1 W5NEF1 PTHR48134:SF2 GLYCOPROTEIN 96-92-RELATED-RELATED TITIN-LIKE LEPOC|Ensembl=ENSLOCG00000001974.1|UniProtKB=W5M1R2 W5M1R2 PTHR45625:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2 isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;cis-trans isomerase activity#GO:0016859;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001663.1|UniProtKB=W5M0L1 W5M0L1 PTHR24083:SF168 NUCLEAR HORMONE RECEPTOR COUP TRANSCRIPTION FACTOR 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;nervous system development#GO:0007399;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000010105.1|UniProtKB=W5MVF6 W5MVF6 PTHR10755:SF0 COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;cellular process#GO:0009987;porphyrin-containing compound biosynthetic process#GO:0006779;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidase#PC00175;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Heme biosynthesis#P02746>Coproporphyrinogen Oxidase (oxygen dependent)#P02980 LEPOC|Ensembl=ENSLOCG00000005648.1|UniProtKB=W5MEN6 W5MEN6 PTHR10336:SF166 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ETA-2 lipase activity#GO:0016298;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;cell communication#GO:0007154 lipase#PC00143;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003393.1|UniProtKB=W5M6L3 W5M6L3 PTHR10340:SF25 SPHINGOMYELIN PHOSPHODIESTERASE ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3B phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000010187.1|UniProtKB=W5MVR6 W5MVR6 PTHR13803:SF1 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24A metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;SNARE binding#GO:0000149;zinc ion binding#GO:0008270 cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vesicle coat#GO:0030120;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;coated membrane#GO:0048475 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000010259.1|UniProtKB=W5MW02 W5MW02 PTHR11746:SF147 O-METHYLTRANSFERASE ACETYLSEROTONIN O-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;O-methyltransferase activity#GO:0008171;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 metabolic process#GO:0008152;regulation of biological quality#GO:0065008;methylation#GO:0032259;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;indole-containing compound metabolic process#GO:0042430;biosynthetic process#GO:0009058;hormone biosynthetic process#GO:0042446;biological regulation#GO:0065007;hormone metabolic process#GO:0042445 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000008698.1|UniProtKB=W5MQD3 W5MQD3 PTHR13271:SF159 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE ACTIN-HISTIDINE N-METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 biological regulation#GO:0065007;regulation of smooth muscle contraction#GO:0006940;regulation of multicellular organismal process#GO:0051239;regulation of muscle system process#GO:0090257;regulation of muscle contraction#GO:0006937;regulation of system process#GO:0044057;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transferase#PC00220;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000006377.1|UniProtKB=W5MH48 W5MH48 PTHR11802:SF471 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE CARBOXYPEPTIDASE carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000002223.1|UniProtKB=W5M2H9 W5M2H9 PTHR22710:SF2 X-RAY RADIATION RESISTANCE ASSOCIATED PROTEIN 1 XRRA1 X-RAY RADIATION RESISTANCE-ASSOCIATED PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008715.1|UniProtKB=W5MQF0 W5MQF0 PTHR12929:SF6 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 3-B-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 nitrogen compound transport#GO:0071705;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;vitamin transport#GO:0051180 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000002078.1|UniProtKB=W5M209 W5M209 PTHR44196:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B PEROXISOMAL REDUCTASE ACTIVATING PPAR-GAMMA membrane#GO:0016020;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000017956.1|UniProtKB=W5NN50 W5NN50 PTHR46291:SF1 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4D LEPOC|Ensembl=ENSLOCG00000016550.1|UniProtKB=W5NII8 W5NII8 PTHR24075:SF6 SEC63 DOMAIN-CONTAINING ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3 ATP-dependent activity, acting on DNA#GO:0008094;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002642.1|UniProtKB=W5M415 W5M415 PTHR24416:SF317 TYROSINE-PROTEIN KINASE RECEPTOR MUSCLE, SKELETAL RECEPTOR TYROSINE-PROTEIN KINASE signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016447.1|UniProtKB=W5NI59 W5NI59 HAAO PTHR15497:SF1 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000001253.1|UniProtKB=W5LZ80 W5LZ80 PTHR43795:SF17 BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE-LIKE PROTEIN 1 lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000015886.1|UniProtKB=W5NG06 W5NG06 PTHR48106:SF18 QUINONE OXIDOREDUCTASE PIG3-RELATED QUINONE OXIDOREDUCTASE PIG3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 LEPOC|Ensembl=ENSLOCG00000006963.1|UniProtKB=W5MJ62 W5MJ62 PTHR10812:SF9 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2 GAMMA transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of cell population proliferation#GO:0042127;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003470.1|UniProtKB=W5M6W2 W5M6W2 PTHR13890:SF0 RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;magnesium ion transmembrane transporter activity#GO:0015095;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;magnesium ion transport#GO:0015693 membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000007027.1|UniProtKB=W5MJE7 W5MJE7 PTHR15298:SF17 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000013238.1|UniProtKB=W5N6P8 W5N6P8 PTHR11848:SF137 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 6 signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP6/7#P06752;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000017089.1|UniProtKB=W5NKF8 W5NKF8 PTHR24006:SF858 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000007746.1|UniProtKB=W5MM07 W5MM07 PTHR10857:SF3 COPINE COPINE-2 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 response to calcium ion#GO:0051592;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to metal ion#GO:0010038;cellular response to chemical stimulus#GO:0070887 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000007627.1|UniProtKB=W5MLJ4 W5MLJ4 PTHR43313:SF60 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C D-BETA-HYDROXYBUTYRATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000009324.1|UniProtKB=W5MSP2 W5MSP2 PTHR23317:SF74 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 8 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of locomotion#GO:0040017;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of signal transduction#GO:0009966;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of cell activation#GO:0050867;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;regulation of cell motility#GO:2000145;positive regulation of lymphocyte activation#GO:0051251;regulation of lymphocyte migration#GO:2000401;regulation of cell communication#GO:0010646;regulation of leukocyte migration#GO:0002685;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;positive regulation of cell adhesion#GO:0045785;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of leukocyte activation#GO:0002696;regulation of multicellular organismal process#GO:0051239;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;regulation of establishment or maintenance of cell polarity#GO:0032878;positive regulation of biological process#GO:0048518;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of lymphocyte activation#GO:0051249;regulation of Rho protein signal transduction#GO:0035023;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;positive regulation of cell motility#GO:2000147;regulation of leukocyte activation#GO:0002694 cellular anatomical structure#GO:0110165;cell leading edge#GO:0031252 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000005256.1|UniProtKB=W5MD71 W5MD71 PTHR14002:SF24 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011613.1|UniProtKB=W5N0X2 W5N0X2 PTHR45641:SF22 TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870) NEPHROCYSTIN-3 anatomical structure morphogenesis#GO:0009653;determination of left/right symmetry#GO:0007368;pattern specification process#GO:0007389;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;renal system development#GO:0072001;kidney development#GO:0001822;determination of bilateral symmetry#GO:0009855;regionalization#GO:0003002;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;developmental process#GO:0032502;left/right pattern formation#GO:0060972;specification of symmetry#GO:0009799;morphogenesis of an epithelium#GO:0002009;animal organ development#GO:0048513;multicellular organism development#GO:0007275 ciliary base#GO:0097546;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000015490.1|UniProtKB=W5NEK6 W5NEK6 PTHR15976:SF17 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;intracellular receptor signaling pathway#GO:0030522;nuclear receptor-mediated signaling pathway#GO:0141193;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010464.1|UniProtKB=W5MWR4 W5MWR4 PTHR12982:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS C PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000005931.1|UniProtKB=W5MFJ9 W5MFJ9 PTHR14611:SF6 TECTONIC FAMILY MEMBER TECTONIC-2 organelle assembly#GO:0070925;cell communication#GO:0007154;localization#GO:0051179;cilium organization#GO:0044782;smoothened signaling pathway#GO:0007224;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;response to stimulus#GO:0050896;cell projection organization#GO:0030030;protein localization to cilium#GO:0061512;signaling#GO:0023052;plasma membrane bounded cell projection assembly#GO:0120031;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012242.1|UniProtKB=W5N354 W5N354 PTHR24253:SF91 TRANSMEMBRANE PROTEASE SERINE COMPLEMENT FACTOR I catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016902.1|UniProtKB=W5NJT6 W5NJT6 PTHR16181:SF31 PROTEIN FAM83A-RELATED PROTEIN FAM83B protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000016074.1|UniProtKB=W5NGP5 W5NGP5 PTHR45793:SF9 HOMEOBOX PROTEIN HOMEOBOX PROTEIN OTX1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 developmental process#GO:0032502;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;head development#GO:0060322;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>OTX#P06818 LEPOC|Ensembl=ENSLOCG00000002084.1|UniProtKB=W5M212 W5M212 PTHR12101:SF15 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166 developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of membrane potential#GO:0042391;animal organ development#GO:0048513;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;heart development#GO:0007507;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological quality#GO:0065008;muscle cell differentiation#GO:0042692;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle structure development#GO:0061061 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;sarcolemma#GO:0042383 LEPOC|Ensembl=ENSLOCG00000012297.1|UniProtKB=W5N3C4 W5N3C4 PTHR12192:SF26 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1 catalytic activity#GO:0003824;lyase activity#GO:0016829 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;cellular process#GO:0009987;catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005841.1|UniProtKB=W5MF94 W5MF94 PTHR46838:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 regulation of cell population proliferation#GO:0042127;regulation of immune effector process#GO:0002697;negative regulation of T cell activation#GO:0050868;regulation of T cell proliferation#GO:0042129;regulation of macromolecule metabolic process#GO:0060255;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of multicellular organismal process#GO:0051241;regulation of biosynthetic process#GO:0009889;negative regulation of cell activation#GO:0050866;positive regulation of locomotion#GO:0040017;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of immune effector process#GO:0002699;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;negative regulation of cell population proliferation#GO:0008285;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cytokine production involved in immune response#GO:0002718;response to stimulus#GO:0050896;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;defense response to Gram-positive bacterium#GO:0050830;positive regulation of multicellular organismal process#GO:0051240;regulation of leukocyte proliferation#GO:0070663;negative regulation of T cell proliferation#GO:0042130;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of biological process#GO:0048518;positive regulation of biosynthetic process#GO:0009891;regulation of cell motility#GO:2000145;response to bacterium#GO:0009617;regulation of lymphocyte migration#GO:2000401;regulation of leukocyte migration#GO:0002685;positive regulation of cytokine production#GO:0001819;response to external biotic stimulus#GO:0043207;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to external stimulus#GO:0009605;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of cell adhesion#GO:0007162;response to other organism#GO:0051707;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of metabolic process#GO:0009893;defense response to bacterium#GO:0042742;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to Gram-negative bacterium#GO:0050829;regulation of lymphocyte activation#GO:0051249;positive regulation of cell motility#GO:2000147;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;negative regulation of cell-cell adhesion#GO:0022408;regulation of T cell activation#GO:0050863;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005940.1|UniProtKB=W5MFL4 W5MFL4 PTHR11537:SF38 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY V MEMBER 1 ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 metal ion transport#GO:0030001;action potential#GO:0001508;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000004994.1|UniProtKB=W5MCA5 W5MCA5 PTHR46647:SF1 RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS LEPOC|Ensembl=ENSLOCG00000011927.1|UniProtKB=W5N205 W5N205 PTHR11193:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;cytoplasm#GO:0005737;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000013636.1|UniProtKB=W5N858 W5N858 PTHR11360:SF123 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 8 monocarboxylic acid transmembrane transporter activity#GO:0008028;active transmembrane transporter activity#GO:0022804;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 regulation of hormone levels#GO:0010817;transport#GO:0006810;hormone transport#GO:0009914;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;localization#GO:0051179;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000886.1|UniProtKB=W5LXZ0 W5LXZ0 PTHR12002:SF27 CLAUDIN CLAUDIN-19 paracellular tight junction channel activity#GO:0160187;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;transporter activity#GO:0005215;binding#GO:0005488;cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515 cellular component biogenesis#GO:0044085;sensory system development#GO:0048880;cellular process#GO:0009987;cellular component assembly#GO:0022607;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;retina development in camera-type eye#GO:0060041;sensory organ development#GO:0007423;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;transport#GO:0006810;cell-cell junction assembly#GO:0007043;multicellular organism development#GO:0007275;paracellular transport#GO:0160184;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;establishment of localization#GO:0051234;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell junction organization#GO:0034330;visual system development#GO:0150063;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;apical junction complex#GO:0043296 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000007635.1|UniProtKB=W5MLK4 W5MLK4 PTHR21463:SF0 ANGIOPOIETIN-LIKE PROTEIN 8 ANGIOPOIETIN-LIKE PROTEIN 8 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 chemical homeostasis#GO:0048878;triglyceride homeostasis#GO:0070328;regulation of lipid metabolic process#GO:0019216;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;lipid homeostasis#GO:0055088;regulation of protein metabolic process#GO:0051246 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000009789.1|UniProtKB=W5MUA9 W5MUA9 PTHR10760:SF3 TORSIN TORSIN-3A endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788;nucleus#GO:0005634;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005597.1|UniProtKB=W5MEE9 W5MEE9 PTHR13348:SF0 RIBONUCLEASE P SUBUNIT P29 RIBONUCLEASE P PROTEIN SUBUNIT P29 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;ribonuclease P complex#GO:0030677;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000006959.1|UniProtKB=W5MJ68 W5MJ68 PTHR22780:SF30 ADAPTIN, ALPHA/GAMMA/EPSILON AP-2 COMPLEX SUBUNIT ALPHA-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;membrane coat#GO:0030117;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;coated vesicle membrane#GO:0030662;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;coated membrane#GO:0048475;coated vesicle#GO:0030135;endocytic vesicle#GO:0030139;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vesicle coat#GO:0030120;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated endocytic vesicle#GO:0045334;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin vesicle coat#GO:0030125 membrane traffic protein#PC00150 Huntington disease#P00029>alpha-Adaptin#P00782 LEPOC|Ensembl=ENSLOCG00000011683.1|UniProtKB=W5N174 W5N174 PTHR10972:SF15 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 3 alcohol binding#GO:0043178;steroid binding#GO:0005496;lipid binding#GO:0008289;cholesterol binding#GO:0015485;binding#GO:0005488;small molecule binding#GO:0036094;sterol binding#GO:0032934 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;cytosol#GO:0005829;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000015839.1|UniProtKB=W5NFT8 W5NFT8 PTHR43289:SF14 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000018084.1|UniProtKB=W5NNH6 W5NNH6 PTHR11937:SF573 ACTIN ACTIN, CYTOPLASMIC 1 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470 LEPOC|Ensembl=ENSLOCG00000002256.1|UniProtKB=W5M2M5 W5M2M5 PTHR15446:SF2 UROPLAKIN III UROPLAKIN-3B-LIKE PROTEIN 1-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017926.1|UniProtKB=W5NN20 W5NN20 PTHR31922:SF2 TRANSMEMBRANE PROTEIN 215 TRANSMEMBRANE PROTEIN 215 LEPOC|Ensembl=ENSLOCG00000017689.1|UniProtKB=W5NMD5 W5NMD5 PTHR40472:SF7 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN PROTEIN RAPUNZEL-RELATED LEPOC|Ensembl=ENSLOCG00000000776.1|UniProtKB=W5LXK3 W5LXK3 PTHR23044:SF84 3'-5' EXONUCLEASE ERI1-RELATED ERI1 EXORIBONUCLEASE 2 RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527 positive regulation of biosynthetic process#GO:0009891;rRNA processing#GO:0006364;regulation of chromatin organization#GO:1902275;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of cellular component organization#GO:0051129;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular component organization#GO:0051128;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000007298.1|UniProtKB=W5MKD0 W5MKD0 PTHR10985:SF136 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED C-HAIRY1A-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of neurogenesis#GO:0050767;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000000674.1|UniProtKB=W5LX88 W5LX88 PTHR11153:SF14 SIDEROFLEXIN SIDEROFLEXIN-2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;intracellular transport#GO:0046907;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular localization#GO:0051641;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;mitochondrial transmembrane transport#GO:1990542 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000005834.1|UniProtKB=W5MF85 W5MF85 PTHR13439:SF5 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 1 cellular process#GO:0009987;membrane assembly#GO:0071709;lipid homeostasis#GO:0055088;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;homeostatic process#GO:0042592;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;membrane organization#GO:0061024;cellular component assembly#GO:0022607;chemical homeostasis#GO:0048878;regulation of membrane lipid distribution#GO:0097035;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003183.1|UniProtKB=W5M5V2 W5M5V2 PTHR11537:SF292 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 1 potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;action potential#GO:0001508;metal ion transport#GO:0030001 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000002043.1|UniProtKB=W5M1W2 W5M1W2 PTHR46061:SF1 THYROTROPIN-RELEASING HORMONE RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH Receptor#P04580 LEPOC|Ensembl=ENSLOCG00000002528.1|UniProtKB=W5M3L0 W5M3L0 PTHR14096:SF59 APOLIPOPROTEIN L APOLIPOPROTEIN L1 ISOFORM X1 lipid binding#GO:0008289;binding#GO:0005488 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000003513.1|UniProtKB=W5M717 W5M717 PTHR13992:SF5 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR NUCLEAR RECEPTOR COREPRESSOR 1 binding#GO:0005488;transcription regulator activity#GO:0140110;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>N-CoR#P00770 LEPOC|Ensembl=ENSLOCG00000007465.1|UniProtKB=W5ML00 W5ML00 PTHR31169:SF2 OS05G0300700 PROTEIN CELL DIVISION CYCLE-ASSOCIATED PROTEIN 7 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000011606.1|UniProtKB=W5N0V8 W5N0V8 PTHR45624:SF3 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 47 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008858.1|UniProtKB=W5MQX1 W5MQX1 PTHR24403:SF62 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 827 double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000010604.1|UniProtKB=W5MX76 W5MX76 PTHR13491:SF0 ZCCHC10 PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10 LEPOC|Ensembl=ENSLOCG00000009748.1|UniProtKB=W5MU74 W5MU74 PTHR11915:SF448 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000000296.1|UniProtKB=W5LW15 W5LW15 PTHR25466:SF11 T-LYMPHOCYTE ACTIVATION ANTIGEN GALECTIN 17-RELATED signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015940.1|UniProtKB=W5NG66 W5NG66 PTHR15304:SF0 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR DOMAIN-CONTAINING PROTEIN regulation of biosynthetic process#GO:0009889;regulation of JNK cascade#GO:0046328;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000004215.1|UniProtKB=W5M9I5 W5M9I5 EIF3B PTHR14068:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000006943.1|UniProtKB=W5MJ59 W5MJ59 PTHR10024:SF115 SYNAPTOTAGMIN SYNAPTOTAGMIN-11 molecular function regulator activity#GO:0098772;lipid binding#GO:0008289;molecular sensor activity#GO:0140299;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543 export from cell#GO:0140352;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular component organization#GO:0016043;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;positive regulation of cellular component organization#GO:0051130;organelle membrane fusion#GO:0090174;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;synaptic vesicle exocytosis#GO:0016079;positive regulation of biological process#GO:0048518;synaptic signaling#GO:0099536;organelle organization#GO:0006996;vesicle organization#GO:0016050;exocytosis#GO:0006887;positive regulation of vesicle fusion#GO:0031340;regulation of localization#GO:0032879;regulation of transport#GO:0051049;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;regulated exocytosis#GO:0045055;vesicle fusion#GO:0006906;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of exocytosis#GO:0017157;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;regulation of secretion#GO:0051046;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;positive regulation of cellular process#GO:0048522;membrane fusion#GO:0061025;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;exocytic vesicle#GO:0070382;axon#GO:0030424;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;neuron projection#GO:0043005;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell junction#GO:0030054 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000007709.1|UniProtKB=W5MLU5 W5MLU5 PTHR11394:SF72 TASTE RECEPTOR TYPE 2 OLFACTORY RECEPTOR CLASS A-LIKE PROTEIN 4 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009466.1|UniProtKB=W5MT48 W5MT48 PTHR12011:SF305 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G7 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014408.1|UniProtKB=W5NAT5 W5NAT5 PTHR11945:SF637 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2A DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;histone deacetylase binding#GO:0042826 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;Oxidative stress response#P00046>MEF-2#P01128 LEPOC|Ensembl=ENSLOCG00000017550.1|UniProtKB=W5NLZ6 W5NLZ6 PTHR12002:SF3 CLAUDIN CLAUDIN-23 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000013660.1|UniProtKB=W5N889 W5N889 PTHR19325:SF549 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING BETA-2-GLYCOPROTEIN 1 defense/immunity protein#PC00090;complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000001888.1|UniProtKB=W5M1F8 W5M1F8 PTHR44303:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;regulation of biological quality#GO:0065008;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;metabolic process#GO:0008152;biological regulation#GO:0065007;macroautophagy#GO:0016236;catabolic process#GO:0009056;regulation of cellular component size#GO:0032535;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017214.1|UniProtKB=W5NKX4 W5NKX4 PTHR21581:SF34 D-ALANYL-D-ALANINE CARBOXYPEPTIDASE TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12 TRAPP complex#GO:0030008;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015831.1|UniProtKB=W5NFT3 W5NFT3 PTHR10741:SF5 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN-ASSOCIATED PROTEIN X catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;RNA binding#GO:0003723 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015595.1|UniProtKB=W5NEZ1 W5NEZ1 PTHR22625:SF61 PLEXIN HEPATOCYTE GROWTH FACTOR RECEPTOR transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cell migration#GO:0030334;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;synapse assembly#GO:0007416;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006621.1|UniProtKB=W5MHY7 W5MHY7 PTHR45864:SF3 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 2 protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488;actin binding#GO:0003779;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;cytoskeletal protein binding#GO:0008092;phosphatase activity#GO:0016791 negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 LEPOC|Ensembl=ENSLOCG00000014498.1|UniProtKB=W5NB33 W5NB33 PTHR10338:SF157 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA (GLOBULIN) INHIBITOR H3 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005056.1|UniProtKB=W5MCK0 W5MCK0 PTHR22115:SF1 C3ORF6 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 50 enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000015844.1|UniProtKB=W5NFU7 W5NFU7 PTHR21847:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;cilium movement#GO:0003341;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;radial spoke#GO:0001534;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000017129.1|UniProtKB=W5NKL2 W5NKL2 PTHR24061:SF5 CALCIUM-SENSING RECEPTOR-RELATED G PROTEIN-COUPLED RECEPTOR FAMILY C GROUP 6 MEMBER A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014012.1|UniProtKB=W5N9G5 W5N9G5 PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004700.1|UniProtKB=W5MB76 W5MB76 PTHR24058:SF12 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1B catalytic activity#GO:0003824;transferase activity#GO:0016740;transcription coregulator activity#GO:0003712;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713;protein serine/threonine kinase activity#GO:0004674;transcription regulator activity#GO:0140110;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009566.1|UniProtKB=W5MTI1 W5MTI1 PTHR45882:SF2 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003469.1|UniProtKB=W5M6W0 W5M6W0 PTHR10971:SF11 MRNA EXPORT FACTOR AND BUB3 MRNA EXPORT FACTOR RAE1 RNA binding#GO:0003723;protein binding#GO:0005515;ubiquitin binding#GO:0043130;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;cellular component organization#GO:0016043;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;nitrogen compound transport#GO:0071705;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008636.1|UniProtKB=W5MQ40 W5MQ40 PTHR10082:SF11 INTEGRIN BETA SUBUNIT INTEGRIN BETA-6 protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839 cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;cell migration#GO:0016477 anchoring junction#GO:0070161;cell junction#GO:0030054;integrin complex#GO:0008305;signaling receptor complex#GO:0043235;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;membrane protein complex#GO:0098796;membrane#GO:0016020 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 LEPOC|Ensembl=ENSLOCG00000010140.1|UniProtKB=W5MVK3 W5MVK3 PTHR11607:SF28 ALPHA-MANNOSIDASE EPIDIDYMIS-SPECIFIC ALPHA-MANNOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121;glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000010986.1|UniProtKB=W5MYL7 W5MYL7 PTHR24366:SF64 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEATS AND IMMUNOGLOBULIN LIKE DOMAINS 2 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000003008.1|UniProtKB=W5M590 W5M590 PTHR12247:SF78 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 4 protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004549.1|UniProtKB=W5MAM8 W5MAM8 PTHR10709:SF11 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1A cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cortical actin cytoskeleton organization#GO:0030866;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 Huntington disease#P00029>Arp2/3 complex#P00811;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 LEPOC|Ensembl=ENSLOCG00000003061.1|UniProtKB=W5M5D8 W5M5D8 PTHR10969:SF4 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 2 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular response to nutrient levels#GO:0031669;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;protein-containing complex disassembly#GO:0032984;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;autophagosome membrane#GO:0000421;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;autophagosome#GO:0005776;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane#GO:0016020 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008181.1|UniProtKB=W5MNH4 W5MNH4 PTHR23503:SF124 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 3 ISOFORM X1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 import across plasma membrane#GO:0098739;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;carbohydrate transport#GO:0008643;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009571.1|UniProtKB=W5MTJ2 W5MTJ2 PTHR46029:SF1 C-TERMINAL-BINDING PROTEIN C-TERMINAL BINDING PROTEIN-LIKE transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000006595.1|UniProtKB=W5MHY0 W5MHY0 PTHR12203:SF126 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 1 pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-xylosyltransferase activity#GO:0035252;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of Notch signaling pathway#GO:0045747;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000015749.1|UniProtKB=W5NFH9 W5NFH9 METAP2 PTHR45777:SF2 METHIONINE AMINOPEPTIDASE 2 METHIONINE AMINOPEPTIDASE 2 exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009321.1|UniProtKB=W5MSL1 W5MSL1 PTHR20859:SF48 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-20 RECEPTOR SUBUNIT BETA cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002926.1|UniProtKB=W5M4Y8 W5M4Y8 PTHR11157:SF171 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000017781.1|UniProtKB=W5NMM6 W5NMM6 PTHR24028:SF260 CADHERIN-87A PROTOCADHERIN-20 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cadherin#PC00057;cell adhesion molecule#PC00069 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000002837.1|UniProtKB=W5M4M8 W5M4M8 PTHR13006:SF7 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 ZINC FINGER PROTEIN 704 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000000567.1|UniProtKB=W5LWX0 W5LWX0 PTHR45944:SF1 SCHNURRI, ISOFORM F TRANSCRIPTION FACTOR HIVEP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000005620.1|UniProtKB=W5MEH7 W5MEH7 PTHR23255:SF49 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ANTI-MUELLERIAN HORMONE TYPE-2 RECEPTOR transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transforming growth factor beta receptor activity#GO:0005024;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>MISRII#P06792 LEPOC|Ensembl=ENSLOCG00000015701.1|UniProtKB=W5NFC0 W5NFC0 PTHR12780:SF1 RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001537.1|UniProtKB=W5M047 W5M047 PTHR11214:SF368 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;aminoglycan biosynthetic process#GO:0006023;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000012747.1|UniProtKB=W5N4X8 W5N4X8 PTHR10913:SF68 FOLLISTATIN-RELATED TOMOREGULIN-1 ISOFORM X1-RELATED developmental process#GO:0032502;cellular process#GO:0009987;cell differentiation#GO:0030154;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000005694.1|UniProtKB=W5MER4 W5MER4 PTHR12245:SF16 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014914.1|UniProtKB=W5NCL1 W5NCL1 PTHR21444:SF16 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 RECEPTOR FOR RETINOL UPTAKE STRA6 establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000001516.1|UniProtKB=W5M035 W5M035 PTHR18898:SF8 NUCLEOPROTEIN TPR-RELATED NUCLEOPROTEIN TPR structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;gene expression#GO:0010467;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of mitotic spindle assembly#GO:1901673;metabolic process#GO:0008152;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular localization#GO:0051641;regulation of mitotic spindle organization#GO:0060236;regulation of spindle assembly#GO:0090169;mRNA export from nucleus#GO:0006406;biological regulation#GO:0065007;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;regulation of organelle assembly#GO:1902115;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA localization#GO:0006403;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;nucleobase-containing compound transport#GO:0015931;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;regulation of microtubule-based process#GO:0032886 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000013729.1|UniProtKB=W5N8H2 W5N8H2 PTHR23235:SF1 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000009618.1|UniProtKB=W5MTR4 W5MTR4 PTHR15653:SF3 STRIATIN STRIATIN-3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 dendritic tree#GO:0097447;dendrite#GO:0030425;cell junction#GO:0030054;cell body#GO:0044297;neuron projection#GO:0043005;postsynapse#GO:0098794;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015950.1|UniProtKB=W5NG81 W5NG81 PTHR23420:SF2 ADENOSYLHOMOCYSTEINASE S-ADENOSYLHOMOCYSTEINE HYDROLASE-LIKE PROTEIN 2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011863.1|UniProtKB=W5N1T1 W5N1T1 PTHR12550:SF42 HEPATOMA-DERIVED GROWTH FACTOR-RELATED PC4 AND SFRS1-INTERACTING PROTEIN cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000010122.1|UniProtKB=W5MVI2 W5MVI2 PTHR13098:SF3 WOLFRAMIN WOLFRAMIN monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to unfolded protein#GO:0006986;cellular response to topologically incorrect protein#GO:0035967;inorganic ion homeostasis#GO:0098771;cellular response to stress#GO:0033554;calcium ion homeostasis#GO:0055074;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;homeostatic process#GO:0042592;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000016437.1|UniProtKB=W5NI42 W5NI42 PTHR10336:SF12 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-1 lipase activity#GO:0016298;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787;calmodulin binding#GO:0005516;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;metabolic process#GO:0008152;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;signal transduction#GO:0007165;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;calcium ion transmembrane transport#GO:0070588;system process#GO:0003008;establishment of localization#GO:0051234;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;intracellular signal transduction#GO:0035556;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;cognition#GO:0050890;phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear speck#GO:0016607;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186 Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;CCKR signaling map#P06959>PLC_beta#P07110;Gonadotropin-releasing hormone receptor pathway#P06664>PLCbeta#P06705;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;Endogenous cannabinoid signaling#P05730>PLC#P05746;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Endothelin signaling pathway#P00019>PLCbeta#P00591;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744 LEPOC|Ensembl=ENSLOCG00000013172.1|UniProtKB=W5N6G4 W5N6G4 PTHR11691:SF62 TYPE I INTERFERON INTERFERON PHI 2-RELATED response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;leukocyte activation#GO:0045321;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cell activation#GO:0001775;cytokine-mediated signaling pathway#GO:0019221;biological regulation#GO:0065007;response to other organism#GO:0051707;adaptive immune response#GO:0002250;multicellular organismal process#GO:0032501;immune response#GO:0006955;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to peptide#GO:1901652;cell activation involved in immune response#GO:0002263;immune system process#GO:0002376;B cell activation involved in immune response#GO:0002312;type I interferon-mediated signaling pathway#GO:0060337;T cell activation involved in immune response#GO:0002286;response to cytokine#GO:0034097;response to chemical#GO:0042221;lymphocyte activation#GO:0046649;defense response to other organism#GO:0098542;signal transduction#GO:0007165;lymphocyte activation involved in immune response#GO:0002285;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;B cell activation#GO:0042113;natural killer cell activation#GO:0030101;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;leukocyte activation involved in immune response#GO:0002366;humoral immune response#GO:0006959 cytokine#PC00083;interferon superfamily#PC00127 LEPOC|Ensembl=ENSLOCG00000007697.1|UniProtKB=W5MLZ6 W5MLZ6 PTHR45653:SF1 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 1 protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cell differentiation#GO:0030154;cell migration#GO:0016477;muscle structure development#GO:0061061;cell motility#GO:0048870;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;myoblast fusion#GO:0007520;striated muscle cell differentiation#GO:0051146;syncytium formation by cell-cell fusion#GO:0000768;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;developmental process#GO:0032502;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 Integrin signalling pathway#P00034>Dock180#P00930 LEPOC|Ensembl=ENSLOCG00000013307.1|UniProtKB=W5N6Y9 W5N6Y9 PTHR24327:SF21 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-4 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;embryo development#GO:0009790;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;embryo development ending in birth or egg hatching#GO:0009792;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000006226.1|UniProtKB=W5MGM5 W5MGM5 PTHR24056:SF599 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 11A-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA processing#GO:0050684;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007813.1|UniProtKB=W5MM86 W5MM86 PTHR10658:SF27 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN BETA ISOFORM lipid binding#GO:0008289;lipid transfer activity#GO:0120013;binding#GO:0005488;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;cation binding#GO:0043169;intramembrane lipid carrier activity#GO:0140303;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylcholine intramembrane carrier activity#GO:0008525;lipid carrier activity#GO:0005319;ion binding#GO:0043167;phosphatidylinositol transfer activity#GO:0008526;phosphatidylcholine binding#GO:0031210;phospholipid binding#GO:0005543;phosphatidylinositol binding#GO:0035091 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005938.1|UniProtKB=W5MFL7 W5MFL7 PTHR45718:SF2 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTION ACTIVATOR GLI1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;smoothened signaling pathway#GO:0007224;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690 LEPOC|Ensembl=ENSLOCG00000015419.1|UniProtKB=W5NEB9 W5NEB9 PTHR45673:SF2 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT GAMMA ISOFORM calmodulin binding#GO:0005516;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;calcineurin-mediated signaling#GO:0097720;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 protein phosphatase#PC00195 B cell activation#P00010>Calcineurin#P00386;Wnt signaling pathway#P00057>Calcineurin#P01446;T cell activation#P00053>Calcineurin#P01315 LEPOC|Ensembl=ENSLOCG00000006062.1|UniProtKB=W5MG18 W5MG18 PTHR23195:SF7 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;SAGA-type complex#GO:0070461;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;nucleus#GO:0005634;chromatin#GO:0000785 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000008000.1|UniProtKB=W5MMV9 W5MMV9 PTHR24023:SF1143 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXIV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000011653.1|UniProtKB=W5N110 W5N110 PTHR10533:SF5 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PRO-NEUROPEPTIDE Y molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;neuropeptide hormone activity#GO:0005184;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855 cell communication#GO:0007154;feeding behavior#GO:0007631;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015052.1|UniProtKB=W5ND14 W5ND14 PTHR28674:SF1 SIMILAR TO DNA SEGMENT, CHR 10, WAYNE STATE UNIVERSITY 102,-EXPRESSED NOP PROTEIN CHAPERONE 1 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-RNA complex assembly#GO:0022618;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000000903.1|UniProtKB=W5LXZ6 W5LXZ6 PTHR11782:SF31 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 8 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462 metabolic process#GO:0008152;nucleoside diphosphate metabolic process#GO:0009132;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate catabolic process#GO:0046434;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000010341.1|UniProtKB=W5MWD4 W5MWD4 PTHR23023:SF204 DIMETHYLANILINE MONOOXYGENASE SI:DKEY-239I20.4 ISOFORM X1 monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015951.1|UniProtKB=W5NG80 W5NG80 PTHR11060:SF0 PROTEIN MEMO1 PROTEIN MEMO1 LEPOC|Ensembl=ENSLOCG00000011742.1|UniProtKB=W5N1D0 W5N1D0 PTHR13284:SF9 GH01354P SELENOCYSTEINE INSERTION SEQUENCE-BINDING PROTEIN 2 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;mRNA 3'-UTR binding#GO:0003730;protein-containing complex binding#GO:0044877 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;translational elongation#GO:0006414;metabolic process#GO:0008152;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008367.1|UniProtKB=W5MP54 W5MP54 PTHR28398:SF1 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 2 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;central element#GO:0000801;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;synaptonemal complex#GO:0000795;condensed chromosome#GO:0000793;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000000880.1|UniProtKB=W5LXW9 W5LXW9 PTHR13962:SF26 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED SI:CH211-145O7.3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000004960.1|UniProtKB=W5MC53 W5MC53 PTHR24208:SF106 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012783.1|UniProtKB=W5N533 W5N533 PTHR23042:SF6 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR 2 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000016864.1|UniProtKB=W5NJN7 W5NJN7 PTHR22968:SF26 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE D3 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>PKC#P00565;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 LEPOC|Ensembl=ENSLOCG00000015266.1|UniProtKB=W5NDT7 W5NDT7 PTHR11200:SF176 INOSITOL 5-PHOSPHATASE INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 membrane#GO:0016020;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000001869.1|UniProtKB=W5M1A9 W5M1A9 PTHR15970:SF8 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR 1 transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000008849.1|UniProtKB=W5MQV7 W5MQV7 PTHR13950:SF12 RABCONNECTIN-RELATED DMX-LIKE PROTEIN 1 localization#GO:0051179;cellular localization#GO:0051641;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000018213.1|UniProtKB=W5NNV5 W5NNV5 PTHR26451:SF866 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003830.1|UniProtKB=W5M8C1 W5M8C1 PTHR24123:SF124 ANKYRIN REPEAT-CONTAINING TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY A MEMBER 1 transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267 response to stimulus#GO:0050896;metal ion transport#GO:0030001;sensory perception of pain#GO:0019233;calcium ion transmembrane transport#GO:0070588;detection of chemical stimulus#GO:0009593;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;cellular process#GO:0009987;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;system process#GO:0003008;calcium ion transport#GO:0006816;sensory perception of chemical stimulus#GO:0007606;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008056.1|UniProtKB=W5MN39 W5MN39 PTHR23036:SF108 CYTOKINE RECEPTOR GROWTH HORMONE RECEPTOR cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089 response to peptide#GO:1901652;positive regulation of signaling#GO:0023056;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;cell surface receptor signaling pathway#GO:0007166;response to cytokine#GO:0034097;response to chemical#GO:0042221;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cytokine-mediated signaling pathway#GO:0019221;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;positive regulation of response to stimulus#GO:0048584;cellular response to nitrogen compound#GO:1901699;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011670.1|UniProtKB=W5N133 W5N133 PTHR14130:SF12 3BP-1 RELATED RHOGAP BARGIN-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000003478.1|UniProtKB=W5M6W9 W5M6W9 PTHR14132:SF24 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transmembrane transport#GO:0034765;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of transmembrane transport#GO:0034762 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015193.1|UniProtKB=W5NDI4 W5NDI4 PTHR11849:SF17 ETS TRANSCRIPTION FACTOR SPI-C DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 Interleukin signaling pathway#P00036>Ets#P00989 LEPOC|Ensembl=ENSLOCG00000012759.1|UniProtKB=W5N4Y9 W5N4Y9 PTHR24394:SF20 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 42 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000005825.1|UniProtKB=W5MF84 W5MF84 PTHR15346:SF0 DYNACTIN SUBUNIT DYNACTIN SUBUNIT 2 protein-membrane adaptor activity#GO:0043495;cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell cycle process#GO:0022402;nuclear migration#GO:0007097;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;localization#GO:0051179;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;intracellular transport#GO:0046907;transport#GO:0006810 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;organelle#GO:0043226 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000016797.1|UniProtKB=W5NJF2 W5NJF2 PTHR18916:SF77 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 3 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cell periphery#GO:0071944;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;microtubule end#GO:1990752;cell cortex#GO:0005938 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004458.1|UniProtKB=W5MAD0 W5MAD0 PTHR12601:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3 CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 organelle localization#GO:0051640;localization#GO:0051179;mitochondrion localization#GO:0051646 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000009144.1|UniProtKB=W5MRY8 W5MRY8 PTHR15718:SF6 G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH C-TERMINAL DOMAIN-CONTAINING PROTEIN G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 3 neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000273.1|UniProtKB=W5LVZ1 W5LVZ1 PTHR48071:SF15 SRCR DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR FAMILY 12 SUBFAMILY J MEMBER 2 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004410.1|UniProtKB=W5MA61 W5MA61 PTHR13398:SF0 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000007131.1|UniProtKB=W5MJS6 W5MJS6 PTHR12566:SF7 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 3 mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182;translation factor activity#GO:0180051;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological quality#GO:0065008;nervous system process#GO:0050877;regulation of synapse organization#GO:0050807;negative regulation of translation#GO:0017148;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of synapse structure or activity#GO:0050803;cognition#GO:0050890;regulation of cell junction assembly#GO:1901888;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;system process#GO:0003008;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;intracellular organelle#GO:0043229;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection#GO:0043005;nucleus#GO:0005634 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000006114.1|UniProtKB=W5MG84 W5MG84 PTHR21481:SF0 PROTEIN CLEC16A PROTEIN CLEC16A regulation of metabolic process#GO:0019222;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;intracellular transport#GO:0046907;transport#GO:0006810;regulation of autophagosome maturation#GO:1901096;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;regulation of catabolic process#GO:0009894;regulation of macroautophagy#GO:0016241;endosomal transport#GO:0016197;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;cellular localization#GO:0051641;localization#GO:0051179 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000005563.1|UniProtKB=W5MEA6 W5MEA6 PTHR23343:SF31 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 4 structural molecule activity#GO:0005198;protein binding#GO:0005515;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;binding#GO:0005488 single fertilization#GO:0007338;negative regulation of biological process#GO:0048519;cellular process#GO:0009987;regulation of biological process#GO:0050789;multicellular organismal process#GO:0032501;regulation of reproductive process#GO:2000241;reproductive process#GO:0022414;fertilization#GO:0009566;biological regulation#GO:0065007;sperm-egg recognition#GO:0035036;cell activation#GO:0001775;cell recognition#GO:0008037;sexual reproduction#GO:0019953;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003538.1|UniProtKB=W5M758 W5M758 PTHR11793:SF10 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR 4 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694 basic helix-loop-helix transcription factor#PC00055 CCKR signaling map#P06959>TCF7L2#P07126 LEPOC|Ensembl=ENSLOCG00000014218.1|UniProtKB=W5NA53 W5NA53 PTHR22804:SF42 AGGRECAN/VERSICAN PROTEOGLYCAN AGGRECAN CORE PROTEIN central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cell junction#GO:0030054;extracellular region#GO:0005576;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;membrane#GO:0016020;cell periphery#GO:0071944 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000006797.1|UniProtKB=W5MIK2 W5MIK2 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000001336.1|UniProtKB=W5LZH6 W5LZH6 PTHR23255:SF64 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-2A molecular transducer activity#GO:0060089;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;signaling receptor activity#GO:0038023;activin binding#GO:0048185;kinase activity#GO:0016301;transferase activity#GO:0016740 signaling#GO:0023052;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;pattern specification process#GO:0007389;activin receptor signaling pathway#GO:0032924;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;catalytic complex#GO:1902494;transferase complex#GO:1990234;signaling receptor complex#GO:0043235;transferase complex, transferring phosphorus-containing groups#GO:0061695;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII/IIB#P06780;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII#P06747 LEPOC|Ensembl=ENSLOCG00000001198.1|UniProtKB=W5LYZ0 W5LYZ0 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000001293.1|UniProtKB=W5LZB7 W5LZB7 HCRTR1 PTHR24241:SF30 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OREXIN_HYPOCRETIN RECEPTOR TYPE 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 neuropeptide signaling pathway#GO:0007218;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009579.1|UniProtKB=W5MTK1 W5MTK1 PTHR12412:SF3 CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule localization#GO:0033036;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;negative regulation of cellular process#GO:0048523;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;catabolic process#GO:0009056;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;RNA localization#GO:0006403;regulation of cellular process#GO:0050794;RNA transport#GO:0050658;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;regulation of mRNA metabolic process#GO:1903311;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000000915.1|UniProtKB=W5LY15 W5LY15 PTHR45810:SF12 HISTONE H3.2 HISTONE H3 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016542.1|UniProtKB=W5NIH9 W5NIH9 PTHR18966:SF38 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2 transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;sodium ion transmembrane transporter activity#GO:0015081;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;molecular transducer activity#GO:0060089 synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268 asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;sodium channel complex#GO:0034706;postsynaptic density membrane#GO:0098839;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA2#P01003;Ionotropic glutamate receptor pathway#P00037>KA#P01026;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 LEPOC|Ensembl=ENSLOCG00000002743.1|UniProtKB=W5M4C0 W5M4C0 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED reverse transcriptase#PC00200;viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000004928.1|UniProtKB=W5MC19 W5MC19 PTHR43157:SF44 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 13 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000010374.1|UniProtKB=W5MWG5 W5MWG5 PTHR22840:SF12 WD REPEAT-CONTAINING PROTEIN 36 WD REPEAT-CONTAINING PROTEIN 36 metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000014468.1|UniProtKB=W5NB04 W5NB04 PTHR24356:SF365 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C DELTA TYPE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs(3)#P06850;Gonadotropin-releasing hormone receptor pathway#P06664>nPKCs#P06852;Apoptosis signaling pathway#P00006>PKCs#P00318;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;B cell activation#P00010>PKC#P00373;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Endothelin signaling pathway#P00019>PKC#P00568;CCKR signaling map#P06959>PKCdelta#P07134;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 LEPOC|Ensembl=ENSLOCG00000013277.1|UniProtKB=W5N6U7 W5N6U7 PTHR12121:SF37 CARBON CATABOLITE REPRESSOR PROTEIN 4 2',5'-PHOSPHODIESTERASE 12 RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000010311.1|UniProtKB=W5MW79 W5MW79 PTHR14145:SF1 26S PROTESOME SUBUNIT 6 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;proteasome regulatory particle, lid subcomplex#GO:0008541 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000003207.1|UniProtKB=W5M5Y5 W5M5Y5 PTHR28652:SF3 TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN TRANSMEMBRANE PROTEIN 59 positive regulation of catabolic process#GO:0009896;positive regulation of metabolic process#GO:0009893;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;positive regulation of autophagy#GO:0010508;regulation of autophagy#GO:0010506;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;lytic vacuole#GO:0000323;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000014241.1|UniProtKB=W5NA77 W5NA77 PTHR15422:SF21 OS05G0565100 PROTEIN TRANSMEMBRANE REDUCTASE CYB561D2 heme binding#GO:0020037;binding#GO:0005488;catalytic activity#GO:0003824;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491 homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;carbohydrate homeostasis#GO:0033500 LEPOC|Ensembl=ENSLOCG00000018023.1|UniProtKB=W5NNB5 W5NNB5 PTHR24072:SF158 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOG catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;chemotaxis#GO:0006935;cortical cytoskeleton organization#GO:0030865;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cell migration#GO:0016477;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;response to external stimulus#GO:0009605;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cellular response to chemical stimulus#GO:0070887;establishment or maintenance of cell polarity#GO:0007163;regulation of biological quality#GO:0065008;Rac protein signal transduction#GO:0016601;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;intracellular signaling cassette#GO:0141124;cytoskeleton organization#GO:0007010;taxis#GO:0042330;response to chemical#GO:0042221;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 small GTPase#PC00208;G-protein#PC00020 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Huntington disease#P00029>Rac#P00775;EGF receptor signaling pathway#P00018>Rac#P00564 LEPOC|Ensembl=ENSLOCG00000013087.1|UniProtKB=W5N669 W5N669 PTHR10529:SF270 AP COMPLEX SUBUNIT MU AP-4 COMPLEX SUBUNIT MU-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 protein targeting#GO:0006605;cytosolic transport#GO:0016482;lysosomal transport#GO:0007041;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vacuolar transport#GO:0007034;establishment of localization#GO:0051234 AP-type membrane coat adaptor complex#GO:0030119;Golgi apparatus#GO:0005794;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006165.1|UniProtKB=W5MGD4 W5MGD4 PTHR19855:SF40 WD40 REPEAT PROTEIN 12, 37 RIBOSOME BIOGENESIS PROTEIN WDR12 metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;90S preribosome#GO:0030686;organelle lumen#GO:0043233;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000001976.1|UniProtKB=W5M1N9 W5M1N9 PTHR45872:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 11 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;signaling receptor binding#GO:0005102;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000009780.1|UniProtKB=W5MUA2 W5MUA2 PTHR24361:SF838 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 22 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000004445.1|UniProtKB=W5MAA1 W5MAA1 PTHR47385:SF10 CALPONIN TRANSGELIN-3 cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 LEPOC|Ensembl=ENSLOCG00000015029.1|UniProtKB=W5ND04 W5ND04 PTHR11670:SF31 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER IRON-RESPONSIVE ELEMENT-BINDING PROTEIN 2 iron-sulfur cluster binding#GO:0051536;RNA binding#GO:0003723;lyase activity#GO:0016829;binding#GO:0005488;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;mRNA binding#GO:0003729;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 LEPOC|Ensembl=ENSLOCG00000013573.1|UniProtKB=W5N7X5 W5N7X5 PTHR46231:SF1 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 1 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012369.1|UniProtKB=W5N3M7 W5N3M7 PTHR11943:SF1 GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate catabolic process#GO:0016052 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992;Fructose galactose metabolism#P02744>Hexose 1-P uridyltransferase#P02964 LEPOC|Ensembl=ENSLOCG00000009877.1|UniProtKB=W5MUL1 W5MUL1 PTHR11454:SF9 INSULIN/INSULIN GROWTH FACTOR INSULIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896 LEPOC|Ensembl=ENSLOCG00000014564.1|UniProtKB=W5NBC1 W5NBC1 PTHR11915:SF461 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 4 ISOFORM X1 binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000010582.1|UniProtKB=W5MX58 W5MX58 PTHR44981:SF4 PERICENTRIN-LIKE PROTEIN, ISOFORM F A-KINASE ANCHOR PROTEIN 9 ISOFORM X1 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;centrosome localization#GO:0051642;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;supramolecular fiber organization#GO:0097435;organelle localization#GO:0051640 LEPOC|Ensembl=ENSLOCG00000010823.1|UniProtKB=W5MY14 W5MY14 PTHR10520:SF12 TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 purine nucleobase metabolic process#GO:0006144;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 De novo purine biosynthesis#P02738>Phosphoribosylamine glycine ligase#P02908 LEPOC|Ensembl=ENSLOCG00000009081.1|UniProtKB=W5MRR0 W5MRR0 PTHR24019:SF13 ADIPOLIN ADIPOLIN hormone activity#GO:0005179;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000015483.1|UniProtKB=W5NEJ6 W5NEJ6 PTHR12489:SF13 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 3 PROTEIN system process#GO:0003008;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004966.1|UniProtKB=W5MC60 W5MC60 PTHR12233:SF2 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26C cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006426.1|UniProtKB=W5MHA4 W5MHA4 PTHR14499:SF3 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015612.1|UniProtKB=W5NF14 W5NF14 PTHR10261:SF0 COATOMER SUBUNIT GAMMA COATOMER SUBUNIT GAMMA-2 Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vesicle coat#GO:0030120;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;COPI-coated vesicle#GO:0030137;endoplasmic reticulum#GO:0005783;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000011030.1|UniProtKB=W5MYU2 W5MYU2 PTHR39319:SF1 SI:DKEY-256H2.1 SI:DKEY-256H2.1 LEPOC|Ensembl=ENSLOCG00000011142.1|UniProtKB=W5MZ81 W5MZ81 PTHR12673:SF13 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 5 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000008664.1|UniProtKB=W5MQ84 W5MQ84 PTHR11909:SF78 CASEIN KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE VRK1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cell communication#GO:0007154 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016163.1|UniProtKB=W5NH09 W5NH09 PTHR23101:SF51 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR 2 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;cytosol#GO:0005829;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000015758.1|UniProtKB=W5NFJ1 W5NFJ1 PTHR17613:SF8 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN PROTEIN 3 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013834.1|UniProtKB=W5N8V2 W5N8V2 PTHR28593:SF6 METEORIN-LIKE PROTEIN METEORIN-LIKE PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;multicellular organismal-level homeostasis#GO:0048871 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013478.1|UniProtKB=W5N7L2 W5N7L2 PTHR18881:SF2 POLYAMINE-MODULATED FACTOR 1-BINDING PROTEIN 1-RELATED POLYAMINE-MODULATED FACTOR 1-BINDING PROTEIN 1 male gamete generation#GO:0048232;gamete generation#GO:0007276;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;developmental process#GO:0032502;spermatogenesis#GO:0007283 cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006216.1|UniProtKB=W5MGK2 W5MGK2 PTHR12011:SF216 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR D1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014677.1|UniProtKB=W5NBR8 W5NBR8 PTHR11616:SF237 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810;amino acid transport#GO:0006865 cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000013071.1|UniProtKB=W5N643 W5N643 PTHR11614:SF198 PHOSPHOLIPASE-RELATED MONOGLYCERIDE LIPASE lipase activity#GO:0016298;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;membrane#GO:0016020 lipase#PC00143;phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000017126.1|UniProtKB=W5NKK4 W5NKK4 PTHR23316:SF10 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-6 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015506.1|UniProtKB=W5NEM2 W5NEM2 PTHR15493:SF8 F-BOX ONLY PROTEIN 5 AND 43 F-BOX ONLY PROTEIN 5 enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of mitotic nuclear division#GO:0045839;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;negative regulation of cell cycle#GO:0045786;G1/S transition of mitotic cell cycle#GO:0000082;negative regulation of chromosome segregation#GO:0051985;regulation of chromosome segregation#GO:0051983;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic sister chromatid segregation#GO:0033047;mitotic cell cycle phase transition#GO:0044772;negative regulation of chromosome organization#GO:2001251;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of reproductive process#GO:2000241;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;regulation of mitotic sister chromatid separation#GO:0010965;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948 intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005973.1|UniProtKB=W5MFS1 W5MFS1 PTHR24166:SF23 ROLLING PEBBLES, ISOFORM B PROTEIN TANC1 regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175 postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;glutamatergic synapse#GO:0098978;intracellular membraneless organelle#GO:0043232;postsynapse#GO:0098794;cell junction#GO:0030054;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013614.1|UniProtKB=W5N823 W5N823 PTHR10855:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome complex#GO:0000502;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000014188.1|UniProtKB=W5NA19 W5NA19 PTHR14217:SF1 INOSITOL-TETRAKISPHOSPHATE 1-KINASE INOSITOL-TETRAKISPHOSPHATE 1-KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000014900.1|UniProtKB=W5NCI8 W5NCI8 PTHR21258:SF63 DOCKING PROTEIN RELATED DOCKING PROTEIN 1-RELATED cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001417.1|UniProtKB=W5LZQ9 W5LZQ9 PTHR16112:SF18 METHYL-CPG BINDING PROTEIN, DROSOPHILA METHYL-CPG-BINDING DOMAIN PROTEIN 5 chromatin binding#GO:0003682;binding#GO:0005488 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000013010.1|UniProtKB=W5N5W6 W5N5W6 PTHR11999:SF68 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE HISTIDINE DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amine metabolic process#GO:0009308;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 lyase#PC00144;decarboxylase#PC00089 CCKR signaling map#P06959>HDC#G07262;CCKR signaling map#P06959>HDC#G06969;Histamine synthesis#P04387>Histidine decarboxylase#P04493 LEPOC|Ensembl=ENSLOCG00000006190.1|UniProtKB=W5MGG8 W5MGG8 PTHR13473:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L48 LARGE RIBOSOMAL SUBUNIT PROTEIN ML48 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000011062.1|UniProtKB=W5MYX0 W5MYX0 PTHR24124:SF3 ANKYRIN REPEAT FAMILY A ANKYRIN REPEAT FAMILY A PROTEIN 2 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005048.1|UniProtKB=W5MCH8 W5MCH8 PTHR46961:SF8 DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN DYNEIN HEAVY CHAIN DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000012303.1|UniProtKB=W5N3D6 W5N3D6 PTHR22741:SF5 P140CAP/SNIP-RELATED SRC KINASE SIGNALING INHIBITOR 1 regulation of cell projection organization#GO:0031344;regulation of dendritic spine morphogenesis#GO:0061001;regulation of synapse organization#GO:0050807;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of developmental process#GO:0050793 postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000008527.1|UniProtKB=W5MPR4 W5MPR4 EEF1D PTHR11595:SF21 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-DELTA guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000005651.1|UniProtKB=W5MEL4 W5MEL4 PTHR12138:SF162 PRIMATE-EXPANDED PROTEIN FAMILY COILED-COIL DOMAIN CONTAINING 122 LEPOC|Ensembl=ENSLOCG00000001169.1|UniProtKB=W5LYW0 W5LYW0 PTHR23282:SF129 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. APICAL ENDOSOMAL GLYCOPROTEIN LEPOC|Ensembl=ENSLOCG00000005699.1|UniProtKB=W5MEV1 W5MEV1 PTHR11477:SF1 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000017600.1|UniProtKB=W5NM46 W5NM46 PTHR24230:SF128 G-PROTEIN COUPLED RECEPTOR BLT1-LIKE1 PROTEIN-RELATED G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004886.1|UniProtKB=W5MBW6 W5MBW6 PTHR24331:SF6 DBX HOMEOBOX PROTEIN DBX1 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357 LEPOC|Ensembl=ENSLOCG00000016966.1|UniProtKB=W5NK13 W5NK13 PTHR24245:SF1 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 63-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003293.1|UniProtKB=W5M679 W5M679 PTHR45740:SF7 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE TIPARP pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000015855.1|UniProtKB=W5NFX0 W5NFX0 PTHR10285:SF69 URIDINE KINASE URIDINE-CYTIDINE KINASE intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000016887.1|UniProtKB=W5NJR5 W5NJR5 PTHR21178:SF8 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 cilium#GO:0005929;9+2 motile cilium#GO:0097729;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006196.1|UniProtKB=W5MGH6 W5MGH6 PTHR12619:SF23 RFX TRANSCRIPTION FACTOR FAMILY MHC CLASS II REGULATORY FACTOR RFX1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000016737.1|UniProtKB=W5NJ80 W5NJ80 PTHR35068:SF1 BEN DOMAIN-CONTAINING PROTEIN 7 BEN DOMAIN-CONTAINING PROTEIN 7 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;regulation of biological process#GO:0050789;hemostasis#GO:0007599;wound healing#GO:0042060;regulation of biological quality#GO:0065008;cell communication#GO:0007154;cell activation#GO:0001775;immune system process#GO:0002376;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;immune response#GO:0006955;coagulation#GO:0050817;cellular process#GO:0009987;response to wounding#GO:0009611;response to stress#GO:0006950;blood coagulation#GO:0007596;platelet activation#GO:0030168 LEPOC|Ensembl=ENSLOCG00000012144.1|UniProtKB=W5N2T0 W5N2T0 PTHR11571:SF141 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE P catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016617.1|UniProtKB=W5NIS7 W5NIS7 PTHR45628:SF10 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1C transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;calcium ion import#GO:0070509;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 Nicotine pharmacodynamics pathway#P06587>CACNA#P06600;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096 LEPOC|Ensembl=ENSLOCG00000003689.1|UniProtKB=W5M7M3 W5M7M3 PTHR20648:SF13 ELONGIN-C ELONGIN-C molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000004632.1|UniProtKB=W5MAZ1 W5MAZ1 PTHR12383:SF16 PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004455.1|UniProtKB=W5MAB6 W5MAB6 PTHR31671:SF2 DIABETES AND OBESITY REGULATED, ISOFORM G TUMOR PROTEIN P53-INDUCIBLE NUCLEAR PROTEIN 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495;transcription coactivator activity#GO:0003713 positive regulation of biological process#GO:0048518;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;macroautophagy#GO:0016236;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;vacuole organization#GO:0007033;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;autophagosome#GO:0005776;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002310.1|UniProtKB=W5M2U6 W5M2U6 PTHR33887:SF5 PB1 DOMAIN-CONTAINING PROTEIN PB1 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007104.1|UniProtKB=W5MJP6 W5MJP6 PTHR15492:SF1 CYCLIN D1-BINDING PROTEIN 1 CYCLIN-D1-BINDING PROTEIN 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000018119.1|UniProtKB=W5NNL1 W5NNL1 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 antigen binding#GO:0003823;binding#GO:0005488 leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000801.1|UniProtKB=W5LXN5 W5LXN5 PTHR39267:SF1 SURVIVAL MOTOR NEURON-LIKE PROTEIN 1 SURVIVAL OF MOTOR NEURON LEPOC|Ensembl=ENSLOCG00000007167.1|UniProtKB=W5MJW2 W5MJW2 PTHR24109:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 31 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 31 LEPOC|Ensembl=ENSLOCG00000017277.1|UniProtKB=W5NL61 W5NL61 PTHR12247:SF72 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008586.1|UniProtKB=W5MPX8 W5MPX8 PTHR15871:SF1 PH DOMAIN-CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY O MEMBER 1 biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;ruffle#GO:0001726;cell projection membrane#GO:0031253 LEPOC|Ensembl=ENSLOCG00000008880.1|UniProtKB=W5MQZ8 W5MQZ8 PTHR11781:SF20 IODOTHYRONINE DEIODINASE TYPE II IODOTHYRONINE DEIODINASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 modified amino acid metabolic process#GO:0006575;phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;metabolic process#GO:0008152;regulation of biological quality#GO:0065008 metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009206.1|UniProtKB=W5MS75 W5MS75 PTHR22594:SF56 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000002751.1|UniProtKB=W5M4C9 W5M4C9 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013506.1|UniProtKB=W5N7P1 W5N7P1 PTHR31504:SF2 ZW10 INTERACTOR ZWINT SI:DKEY-225F5.4 LEPOC|Ensembl=ENSLOCG00000014981.1|UniProtKB=W5NCT4 W5NCT4 PTHR14136:SF17 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 LEPOC|Ensembl=ENSLOCG00000003764.1|UniProtKB=W5M7Y1 W5M7Y1 PTHR10177:SF60 CYCLINS CYCLIN-G2 enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000006157.1|UniProtKB=W5MGD0 W5MGD0 PTHR24078:SF553 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 13 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004204.1|UniProtKB=W5M9G2 W5M9G2 PTHR28474:SF1 TRANSMEMBRANE PROTEIN 72 TRANSMEMBRANE PROTEIN 72 LEPOC|Ensembl=ENSLOCG00000017879.1|UniProtKB=W5NMX3 W5NMX3 PTHR11984:SF105 CONNEXIN GAP JUNCTION PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cell communication#GO:0007154;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;anchoring junction#GO:0070161 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000009529.1|UniProtKB=W5MTE4 W5MTE4 PTHR14514:SF2 PKA ANCHORING PROTEIN A-KINASE ANCHOR PROTEIN 6 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of membrane potential#GO:0042391;regulation of system process#GO:0044057;regulation of monoatomic cation transmembrane transport#GO:1904062;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of multicellular organismal process#GO:0051239;regulation of monoatomic ion transport#GO:0043269;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of biological quality#GO:0065008;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of muscle system process#GO:0090257;regulation of transmembrane transport#GO:0034762 sarcoplasmic reticulum#GO:0016529;nucleus#GO:0005634;membrane#GO:0016020;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;sarcoplasm#GO:0016528;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016300.1|UniProtKB=W5NHK7 W5NHK7 PTHR46957:SF1 CYTOKINE RECEPTOR PHOSPHATIDYLINOSITOL PHOSPHATASE PTPRQ nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;detection of mechanical stimulus#GO:0050982;response to external stimulus#GO:0009605;system process#GO:0003008;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605;response to stimulus#GO:0050896 signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003369.1|UniProtKB=W5M6I0 W5M6I0 PTHR42854:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED translation initiation factor activity#GO:0003743;tRNA binding#GO:0000049;RNA binding#GO:0003723;translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676 cytoplasmic translational initiation#GO:0002183;translational initiation#GO:0006413;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000004136.1|UniProtKB=W5M995 W5M995 PTHR10947:SF0 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 PHENYLALANINE--TRNA LIGASE BETA SUBUNIT catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014864.1|UniProtKB=W5NCE6 W5NCE6 PTHR34490:SF1 PROTEIN CBG12054-RELATED GALAXIN-LIKE LEPOC|Ensembl=ENSLOCG00000004634.1|UniProtKB=W5MAZ5 W5MAZ5 PTHR12736:SF5 LANC-LIKE PROTEIN GLUTATHIONE S-TRANSFERASE LANCL1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 response to stimulus#GO:0050896;response to toxic substance#GO:0009636;regulation of cellular response to alcohol#GO:1905957;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of response to alcohol#GO:1901419;cellular response to chemical stimulus#GO:0070887;regulation of abscisic acid-activated signaling pathway#GO:0009787;cellular detoxification#GO:1990748;regulation of signaling#GO:0023051;response to chemical#GO:0042221;detoxification#GO:0098754;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to toxic substance#GO:0097237;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583 LEPOC|Ensembl=ENSLOCG00000002006.1|UniProtKB=W5M1R5 W5M1R5 PTHR24070:SF199 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-B ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 Ras Pathway#P04393>Ral#P04550 LEPOC|Ensembl=ENSLOCG00000012080.1|UniProtKB=W5N2L1 W5N2L1 PTHR24169:SF9 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;response to peptide#GO:1901652;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;intracellular signaling cassette#GO:0141124;defense response to other organism#GO:0098542;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular process#GO:0009987;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;non-canonical NF-kappaB signal transduction#GO:0038061;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;response to other organism#GO:0051707;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;canonical NF-kappaB signal transduction#GO:0007249;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Apoptosis signaling pathway#P00006>NFkappaB#P00297;B cell activation#P00010>NFkappaB#P00370;Toll receptor signaling pathway#P00054>NFkappaB#P01354;T cell activation#P00053>NFkappaB#P01298 LEPOC|Ensembl=ENSLOCG00000018163.1|UniProtKB=W5NNQ5 W5NNQ5 PTHR10489:SF922 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 2 ISOFORM X1-RELATED protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896 response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;cell communication#GO:0007154;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;locomotion#GO:0040011;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000013643.1|UniProtKB=W5N859 W5N859 PTHR45931:SF30 SI:CH211-59O9.10 RING-TYPE E3 UBIQUITIN TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000005901.1|UniProtKB=W5MFH2 W5MFH2 PTHR15921:SF3 PRE-MRNA CLEAVAGE COMPLEX II PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11 enzyme binding#GO:0019899;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA polymerase II complex binding#GO:0000993;RNA binding#GO:0003723;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;RNA polymerase core enzyme binding#GO:0043175 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;macromolecule metabolic process#GO:0043170;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004677.1|UniProtKB=W5MB44 W5MB44 PTHR23410:SF12 RIBOSOMAL PROTEIN L5-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL18 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of protein metabolic process#GO:0051247;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;ribosomal large subunit assembly#GO:0000027 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000002830.1|UniProtKB=W5M4N0 W5M4N0 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010358.1|UniProtKB=W5MWD8 W5MWD8 PTHR24064:SF682 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 5-LIKE transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;quaternary ammonium group transmembrane transporter activity#GO:0015651 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000001411.1|UniProtKB=W5LZQ4 W5LZQ4 PTHR12814:SF2 RNA-BINDING PROTEIN NOB1 RNA-BINDING PROTEIN NOB1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000012069.1|UniProtKB=W5N2J2 W5N2J2 PTHR47014:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY S MEMBER 1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY S MEMBER 1 LEPOC|Ensembl=ENSLOCG00000012971.1|UniProtKB=W5N5S4 W5N5S4 PTHR11347:SF85 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8A cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular response to growth factor stimulus#GO:0071363;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;response to endogenous stimulus#GO:0009719;positive regulation of MAPK cascade#GO:0043410;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009882.1|UniProtKB=W5MUQ9 W5MUQ9 PTHR46276:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR5 E3 UBIQUITIN-PROTEIN LIGASE UBR5 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 regulation of signaling#GO:0023051;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;positive regulation of canonical Wnt signaling pathway#GO:0090263;macromolecule metabolic process#GO:0043170;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;post-translational protein modification#GO:0043687;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 Hedgehog signaling pathway#P00025>Ubiquitin ligase#P00693 LEPOC|Ensembl=ENSLOCG00000006494.1|UniProtKB=W5MHI6 W5MHI6 PTHR10558:SF1 SOMATOSTATIN CORTISTATIN signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;neuropeptide hormone activity#GO:0005184 regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000002483.1|UniProtKB=W5M3G0 W5M3G0 PTHR11267:SF209 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX20 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cell fate specification#GO:0001708;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 LEPOC|Ensembl=ENSLOCG00000016108.1|UniProtKB=W5NGT8 W5NGT8 PTHR11339:SF289 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED VWFD DOMAIN-CONTAINING PROTEIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000016781.1|UniProtKB=W5NJD5 W5NJD5 PTHR47507:SF2 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR-LIKE PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793 LEPOC|Ensembl=ENSLOCG00000002028.1|UniProtKB=W5M1U9 W5M1U9 PTHR45718:SF6 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTION ACTIVATOR GLI2 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 smoothened signaling pathway#GO:0007224;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690 LEPOC|Ensembl=ENSLOCG00000007999.1|UniProtKB=W5MMV2 W5MMV2 PTHR11071:SF292 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015905.1|UniProtKB=W5NG30 W5NG30 PTHR11202:SF1 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER PROTEIN ENABLED HOMOLOG protein binding#GO:0005515;binding#GO:0005488 neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;actin polymerization or depolymerization#GO:0008154;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;system development#GO:0048731;anatomical structure development#GO:0048856;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cytoskeleton organization#GO:0007010;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030 anchoring junction#GO:0070161;cell junction#GO:0030054;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 Axon guidance mediated by Slit/Robo#P00008>Mena#P00345;Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516;Axon guidance mediated by netrin#P00009>Ena#P00361 LEPOC|Ensembl=ENSLOCG00000004862.1|UniProtKB=W5MBS8 W5MBS8 PTHR20843:SF1 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 10 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000001715.1|UniProtKB=W5M0S8 W5M0S8 PTHR22896:SF1 CDK5 AND ABL1 ENZYME SUBSTRATE 1 CDK5 AND ABL1 ENZYME SUBSTRATE 1 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;nervous system development#GO:0007399;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000012402.1|UniProtKB=W5N3R6 W5N3R6 PTHR46362:SF1 GEM-ASSOCIATED PROTEIN 5 GEM-ASSOCIATED PROTEIN 5 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;SMN complex#GO:0032797;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 LEPOC|Ensembl=ENSLOCG00000015687.1|UniProtKB=W5NFA1 W5NFA1 PTHR24365:SF522 TOLL-LIKE RECEPTOR TIR DOMAIN-CONTAINING PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 toll-like receptor signaling pathway#GO:0002224;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;cell communication#GO:0007154;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011170.1|UniProtKB=W5MZB5 W5MZB5 PTHR13274:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN MS25 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000012310.1|UniProtKB=W5N3D2 W5N3D2 PTHR28596:SF1 BBSOME-INTERACTING PROTEIN 1 BBSOME-INTERACTING PROTEIN 1 cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;organelle assembly#GO:0070925;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cilium assembly#GO:0060271;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;ciliary membrane#GO:0060170;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;BBSome#GO:0034464;plasma membrane region#GO:0098590;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000001266.1|UniProtKB=W5LZ78 W5LZ78 PTHR24329:SF576 HOMEOBOX PROTEIN ARISTALESS SI:DKEY-43P13.5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000008409.1|UniProtKB=W5MPC4 W5MPC4 PTHR45638:SF6 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ALPHA-3 channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553 sensory system development#GO:0048880;cellular process#GO:0009987;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;retina development in camera-type eye#GO:0060041;monoatomic cation transmembrane transport#GO:0098655;sensory perception of chemical stimulus#GO:0007606;sensory organ development#GO:0007423;transport#GO:0006810;developmental process#GO:0032502;animal organ development#GO:0048513;establishment of localization#GO:0051234;multicellular organism development#GO:0007275;system process#GO:0003008;visual system development#GO:0150063;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;transmembrane transport#GO:0055085;anatomical structure development#GO:0048856;monoatomic cation transport#GO:0006812;localization#GO:0051179;eye development#GO:0001654;monoatomic ion transport#GO:0006811;system development#GO:0048731 cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141;ion channel#PC00133 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 LEPOC|Ensembl=ENSLOCG00000018137.1|UniProtKB=W5NNM9 W5NNM9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010045.1|UniProtKB=W5MV76 W5MV76 PTHR14614:SF13 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE METHYLTRANSFERASE METTL21C lysine N-methyltransferase activity#GO:0016278;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007420.1|UniProtKB=W5MKU8 W5MKU8 PTHR12121:SF35 CARBON CATABOLITE REPRESSOR PROTEIN 4 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;CCR4-NOT complex#GO:0030014;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000006617.1|UniProtKB=W5MI13 W5MI13 PTHR45750:SF2 GH11602P HISTONE ACETYLTRANSFERASE KAT2B acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;chromatin remodeling#GO:0006338;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248 p53 pathway#P00059>PCAF#P04629;Gonadotropin-releasing hormone receptor pathway#P06664>Pcaf#P06715 LEPOC|Ensembl=ENSLOCG00000013361.1|UniProtKB=W5N761 W5N761 PTHR24251:SF24 OVOCHYMASE-RELATED PROCOLLAGEN C-ENDOPEPTIDASE ENHANCER 1 collagen binding#GO:0005518;binding#GO:0005488;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme activator activity#GO:0008047;peptidase activator activity#GO:0016504;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016378.1|UniProtKB=W5NHX0 W5NHX0 PTHR10151:SF77 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 1 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;regulation of developmental process#GO:0050793;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;localization#GO:0051179;regulation of bone mineralization#GO:0030500;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;establishment of localization#GO:0051234;negative regulation of cellular process#GO:0048523;transport#GO:0006810;regulation of cell differentiation#GO:0045595;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;nucleotide metabolic process#GO:0009117;inorganic anion transport#GO:0015698;ribonucleotide metabolic process#GO:0009259;regulation of multicellular organismal process#GO:0051239;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152 extracellular region#GO:0005576;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane region#GO:0098590 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011914.1|UniProtKB=W5N1Y9 W5N1Y9 PTHR24237:SF44 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001111.1|UniProtKB=W5LYP1 W5LYP1 PTHR34762:SF1 SMALL VASOHIBIN-BINDING PROTEIN SMALL VASOHIBIN-BINDING PROTEIN transport#GO:0006810;regulation of protein ubiquitination#GO:0031396;negative regulation of cellular process#GO:0048523;establishment of protein localization to extracellular region#GO:0035592;regulation of protein modification process#GO:0031399;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;establishment of protein localization#GO:0045184;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;biological regulation#GO:0065007;negative regulation of protein ubiquitination#GO:0031397;protein transport#GO:0015031;secretion by cell#GO:0032940;secretion#GO:0046903;regulation of post-translational protein modification#GO:1901873;localization#GO:0051179;protein secretion#GO:0009306;protein localization to extracellular region#GO:0071692;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;export from cell#GO:0140352;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177 LEPOC|Ensembl=ENSLOCG00000001740.1|UniProtKB=W5M0Y9 W5M0Y9 PTHR22589:SF74 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 1, LIVER ISOFORM acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carnitine metabolic process#GO:0009437;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012022.1|UniProtKB=W5N2C8 W5N2C8 PTHR24020:SF37 COLLAGEN ALPHA VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 2 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000016073.1|UniProtKB=W5NGP9 W5NGP9 PTHR21584:SF10 DIFFERENTIAL DISPLAY AND ACTIVATED BY P53 DDA3 /G2 S PHASE EXPRESSED 1 G2 AND S PHASE-EXPRESSED PROTEIN 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoplasmic microtubule#GO:0005881;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 p53 pathway#P00059>B99#G04697;p53 pathway#P00059>B99#P04613 LEPOC|Ensembl=ENSLOCG00000016928.1|UniProtKB=W5NJW8 W5NJW8 PTHR11956:SF11 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000011819.1|UniProtKB=W5N1M1 W5N1M1 PTHR45659:SF10 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000005920.1|UniProtKB=W5MFK4 W5MFK4 PTHR13371:SF0 GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN CENTROSOMAL PROTEIN OF 104 KDA cilium#GO:0005929;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011775.1|UniProtKB=W5N1H1 W5N1H1 PTHR31837:SF3 CYTOCHROME B-245 CHAPERONE 1 CYTOCHROME B-245 CHAPERONE 1 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;cellular process#GO:0009987;defense response to other organism#GO:0098542;response to other organism#GO:0051707;metabolic process#GO:0008152;immune effector process#GO:0002252;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012724.1|UniProtKB=W5N4V6 W5N4V6 PTHR11958:SF24 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 1 sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;solute:monoatomic cation symporter activity#GO:0015294;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;sodium ion transmembrane transporter activity#GO:0015081;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857 nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;aspartate transmembrane transport#GO:0015810;cellular process#GO:0009987;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;import into cell#GO:0098657;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;L-glutamate import#GO:0051938;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 LEPOC|Ensembl=ENSLOCG00000007717.1|UniProtKB=W5MLV7 W5MLV7 PTHR19818:SF167 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 4 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011767.1|UniProtKB=W5N1G0 W5N1G0 PTHR11346:SF190 GALECTIN GALECTIN carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000008275.1|UniProtKB=W5MNU5 W5MNU5 PTHR45949:SF3 SORTING NEXIN-4 SORTING NEXIN-7 mitophagy#GO:0000423;establishment of localization#GO:0051234;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;reticulophagy#GO:0061709;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;localization within membrane#GO:0051668;endocytic recycling#GO:0032456;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;phagophore assembly site#GO:0000407 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015273.1|UniProtKB=W5NDT3 W5NDT3 PTHR12611:SF4 PUR-TRANSCRIPTIONAL ACTIVATOR TRANSCRIPTIONAL REGULATOR PROTEIN PUR-BETA transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007379.1|UniProtKB=W5MKN9 W5MKN9 PTHR12498:SF0 N-TERMINAL ASPARAGINE AMIDOHYDROLASE PROTEIN N-TERMINAL ASPARAGINE AMIDOHYDROLASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000574.1|UniProtKB=W5LWX8 W5LWX8 PTHR10779:SF31 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 binding#GO:0005488;protein binding#GO:0005515 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dynein complex#GO:0030286 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008149.1|UniProtKB=W5MND6 W5MND6 PTHR10411:SF4 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of JNK cascade#GO:0046328;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;positive regulation of JNK cascade#GO:0046330;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 p53 pathway#P00059>GADD45#G01575;p53 pathway#P00059>GADD45#P04626 LEPOC|Ensembl=ENSLOCG00000003298.1|UniProtKB=W5M681 W5M681 PTHR31120:SF7 METALLOPROTEASE TIKI METALLOPROTEASE TIKI1 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000001946.1|UniProtKB=W5M1K0 W5M1K0 PTHR14689:SF0 PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 82 LEPOC|Ensembl=ENSLOCG00000004502.1|UniProtKB=W5MAG9 W5MAG9 PTHR31573:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2 DNA OXIDATIVE DEMETHYLASE ALKBH2 transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;cation binding#GO:0043169;hydrolase activity#GO:0016787;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;binding#GO:0005488;metal ion binding#GO:0046872;ferrous iron binding#GO:0008198;catalytic activity, acting on DNA#GO:0140097;demethylase activity#GO:0032451;iron ion binding#GO:0005506 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000009617.1|UniProtKB=W5MTP3 W5MTP3 PTHR32343:SF6 SERINE/ARGININE-RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 11 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000010840.1|UniProtKB=W5MY28 W5MY28 PTHR12300:SF189 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum tubular network organization#GO:0071786;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;endoplasmic reticulum tubular network#GO:0071782;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic microtubule#GO:0005881;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008427.1|UniProtKB=W5MPF4 W5MPF4 PTHR46785:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B LEPOC|Ensembl=ENSLOCG00000013858.1|UniProtKB=W5N8Y7 W5N8Y7 PTHR47448:SF2 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000010380.1|UniProtKB=W5MWF8 W5MWF8 PTHR11494:SF10 CYTOTOXIC T-LYMPHOCYTE PROTEIN CYTOTOXIC T-LYMPHOCYTE PROTEIN 4 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;immune system process#GO:0002376;cell communication#GO:0007154;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;T cell receptor signaling pathway#GO:0050852;immune response-activating signaling pathway#GO:0002757 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017856.1|UniProtKB=W5NMV0 W5NMV0 PTHR22750:SF10 G-PROTEIN COUPLED RECEPTOR CANNABINOID RECEPTOR 2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001470.1|UniProtKB=W5LZX5 W5LZX5 PTHR11848:SF78 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 15 signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000006425.1|UniProtKB=W5MHA3 W5MHA3 PTHR46505:SF1 OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012535.1|UniProtKB=W5N480 W5N480 PTHR43108:SF6 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-SULPHOGLUCOSAMINE SULPHOHYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;protein catabolic process#GO:0030163;glycosaminoglycan catabolic process#GO:0006027;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007872.1|UniProtKB=W5MMF1 W5MMF1 PTHR13261:SF0 BRCA2 AND CDKN1A INTERACTING PROTEIN BRCA2 AND CDKN1A-INTERACTING PROTEIN kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 microtubule cytoskeleton organization#GO:0000226;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;regulation of protein modification process#GO:0031399;microtubule anchoring#GO:0034453;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;mitotic spindle pole#GO:0097431;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000013490.1|UniProtKB=W5N7M3 W5N7M3 PTHR13555:SF25 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1A C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000010792.1|UniProtKB=W5MXW8 W5MXW8 PTHR13710:SF166 DNA HELICASE RECQ FAMILY MEMBER BIFUNCTIONAL 3'-5' EXONUCLEASE_ATP-DEPENDENT HELICASE WRN helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;telomere organization#GO:0032200;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 chromosome#GO:0005694;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228 DNA helicase#PC00011;DNA metabolism protein#PC00009 p53 pathway#P00059>WRN#P04617 LEPOC|Ensembl=ENSLOCG00000018332.1|UniProtKB=W5NP74 W5NP74 PTHR46473:SF14 GH08155P LEUCINE RICH REPEAT CONTAINING 3B binding#GO:0005488;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;potassium channel regulator activity#GO:0015459;protein binding#GO:0005515;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;molecular function activator activity#GO:0140677;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;potassium channel activity#GO:0005267;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;channel regulator activity#GO:0016247;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 LEPOC|Ensembl=ENSLOCG00000017338.1|UniProtKB=W5NLD4 W5NLD4 PTHR24203:SF75 ANKYRIN REPEAT FAMILY PROTEIN NOTCH-REGULATED ANKYRIN REPEAT-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007330.1|UniProtKB=W5MKG5 W5MKG5 PTHR21713:SF3 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM protein targeting#GO:0006605;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000001485.1|UniProtKB=W5M002 W5M002 PTHR12734:SF0 METHYLTRANSFERASE-RELATED 18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE rRNA methyltransferase activity#GO:0008649;rRNA (guanine) methyltransferase activity#GO:0016435;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;organelle localization#GO:0051640;nuclear export#GO:0051168;rRNA processing#GO:0006364;nuclear transport#GO:0051169;localization#GO:0051179;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;rRNA metabolic process#GO:0016072;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005168.1|UniProtKB=W5MCX0 W5MCX0 PTHR23280:SF18 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 4B cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cell adhesion#GO:0045785;organelle organization#GO:0006996;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000003736.1|UniProtKB=W5M7T2 W5M7T2 PTHR46013:SF9 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000014816.1|UniProtKB=W5NC85 W5NC85 PTHR24028:SF276 CADHERIN-87A PROTOCADHERIN-20 cell adhesion#GO:0007155;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000017455.1|UniProtKB=W5NLQ1 W5NLQ1 PTHR26451:SF847 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000867.1|UniProtKB=W5LXV9 W5LXV9 PTHR45828:SF44 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000016128.1|UniProtKB=W5NGW3 W5NGW3 PTHR12301:SF8 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 5 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000005643.1|UniProtKB=W5MEK6 W5MEK6 PTHR15496:SF2 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 transcription factor TFIIIC complex#GO:0000127;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007608.1|UniProtKB=W5MLH0 W5MLH0 PTHR24327:SF33 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;skeletal system development#GO:0001501;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development ending in birth or egg hatching#GO:0009792;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000010876.1|UniProtKB=W5MY68 W5MY68 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004908.1|UniProtKB=W5MBZ4 W5MBZ4 PTHR46309:SF28 PHD FINGER PROTEIN 12 PHD FINGER PROTEIN 12 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;chromosome#GO:0005694;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016800.1|UniProtKB=W5NJF6 W5NJF6 PTHR47141:SF1 CYSTATIN-F CYSTATIN-F endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 regulation of system process#GO:0044057;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of cell activation#GO:0050866;regulation of macrophage activation#GO:0043030;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of nervous system development#GO:0051960;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;negative regulation of inflammatory response#GO:0050728;regulation of immune system process#GO:0002682;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole#GO:0000323;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000012940.1|UniProtKB=W5N5N7 W5N5N7 PTHR14058:SF11 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 2 binding#GO:0005488;peptide binding#GO:0042277 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126 LEPOC|Ensembl=ENSLOCG00000010233.1|UniProtKB=W5MVX4 W5MVX4 PTHR45667:SF9 S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN MITOCHONDRIAL S-ADENOSYLMETHIONINE CARRIER PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 mitochondrial carrier protein#PC00158 LEPOC|Ensembl=ENSLOCG00000014810.1|UniProtKB=W5NC75 W5NC75 PTHR10185:SF16 PHOSPHOLIPASE D - RELATED 5'-3' EXONUCLEASE PLD3 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000008031.1|UniProtKB=W5MMZ7 W5MMZ7 PTHR10556:SF59 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE VERY-LONG-CHAIN ENOYL-COA REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000018013.1|UniProtKB=W5NNA5 W5NNA5 PTHR22750:SF47 G-PROTEIN COUPLED RECEPTOR CANNABINOID RECEPTOR 1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Endogenous cannabinoid signaling#P05730>CB1#P05743 LEPOC|Ensembl=ENSLOCG00000001455.1|UniProtKB=W5LZW0 W5LZW0 PTHR47965:SF40 ASPARTYL PROTEASE-RELATED BETA-SECRETASE 2 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;membrane protein ectodomain proteolysis#GO:0006509;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 protease#PC00190 Alzheimer disease-presenilin pathway#P00004>Pro-BACE-1#P00162;Alzheimer disease-amyloid secretase pathway#P00003>Pro-BACE-1#P00081;Alzheimer disease-presenilin pathway#P00004>BACE-1 pro-domain#P00178;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1 pro-domain#P00094;Alzheimer disease-presenilin pathway#P00004>BACE-1#P00172;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1#P00101 LEPOC|Ensembl=ENSLOCG00000002467.1|UniProtKB=W5M3D6 W5M3D6 PTHR24393:SF151 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 956 transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000007961.1|UniProtKB=W5MMR0 W5MMR0 PTHR45917:SF15 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 2A ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;system process#GO:0003008;response to external stimulus#GO:0009605;response to abiotic stimulus#GO:0009628;sensory perception of light stimulus#GO:0050953;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;sensory perception of sound#GO:0007605;visual perception#GO:0007601;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;signaling#GO:0023052;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;cell communication#GO:0007154 LEPOC|Ensembl=ENSLOCG00000010612.1|UniProtKB=W5MX97 W5MX97 PTHR45678:SF13 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED MITOCHONDRIAL GLUTAMATE CARRIER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014877.1|UniProtKB=W5NCG3 W5NCG3 PTHR10083:SF391 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED BPTI_KUNITZ DOMAIN-CONTAINING PROTEIN PRECURSOR serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000014403.1|UniProtKB=W5NAU0 W5NAU0 PTHR11920:SF349 GUANYLYL CYCLASE RETINAL GUANYLYL CYCLASE 2 lyase activity#GO:0016829;molecular transducer activity#GO:0060089;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653 nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cyclic nucleotide biosynthetic process#GO:0009190;nervous system process#GO:0050877;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;sensory perception#GO:0007600;nucleoside phosphate metabolic process#GO:0006753;visual perception#GO:0007601;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;sensory perception of light stimulus#GO:0050953;system process#GO:0003008;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;multicellular organismal process#GO:0032501;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260 cilium#GO:0005929;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750 lyase#PC00144;guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000015763.1|UniProtKB=W5NFJ8 W5NFJ8 PTHR23113:SF168 GUANINE NUCLEOTIDE EXCHANGE FACTOR SON OF SEVENLESS HOMOLOG 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 CCKR signaling map#P06959>SOS1#P07061;B cell activation#P00010>SOS#P00379;Angiogenesis#P00005>SOS-1#P00193;PDGF signaling pathway#P00047>SOS#P01159;EGF receptor signaling pathway#P00018>SOS#P00558;Integrin signalling pathway#P00034>SOS#P00920;PI3 kinase pathway#P00048>SOS#P01185;FGF signaling pathway#P00021>SOS#P00641;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883;T cell activation#P00053>SOS#P01307;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Sos#P00850;Gonadotropin-releasing hormone receptor pathway#P06664>Sos#P06849;Ras Pathway#P04393>SOS#P04552;Interleukin signaling pathway#P00036>SOS#P00981 LEPOC|Ensembl=ENSLOCG00000013168.1|UniProtKB=W5N6G5 W5N6G5 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 carbohydrate kinase#PC00065;metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 Fructose galactose metabolism#P02744>Galactokinase#P02960 LEPOC|Ensembl=ENSLOCG00000018139.1|UniProtKB=W5NNN1 W5NNN1 PTHR12002:SF35 CLAUDIN CLAUDIN-5 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000003173.1|UniProtKB=W5M5U9 W5M5U9 PTHR24416:SF125 TYROSINE-PROTEIN KINASE RECEPTOR ANGIOPOIETIN-1 RECEPTOR catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;positive regulation of cell motility#GO:2000147;blood vessel morphogenesis#GO:0048514;positive regulation of angiogenesis#GO:0045766;positive regulation of signaling#GO:0023056;angiogenesis#GO:0001525;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;epithelial cell proliferation#GO:0050673;endothelial cell proliferation#GO:0001935;regulation of anatomical structure morphogenesis#GO:0022603;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;positive regulation of signal transduction#GO:0009967;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;system development#GO:0048731;regulation of angiogenesis#GO:0045765;regulation of cell motility#GO:2000145;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell population proliferation#GO:0008283;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of locomotion#GO:0040017;positive regulation of MAPK cascade#GO:0043410;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of vasculature development#GO:1901342 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Tie2#P00247 LEPOC|Ensembl=ENSLOCG00000016741.1|UniProtKB=W5NJ84 W5NJ84 PTHR11685:SF234 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING RBR-TYPE E3 UBIQUITIN TRANSFERASE protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016664.1|UniProtKB=W5NIX7 W5NIX7 PTHR15361:SF4 RAD51/NUKS-INTERACTING PROTEIN RAD51-ASSOCIATED PROTEIN 1 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974 LEPOC|Ensembl=ENSLOCG00000009870.1|UniProtKB=W5MUL5 W5MUL5 PTHR24257:SF22 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 3B serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009569.1|UniProtKB=W5MTI7 W5MTI7 PTHR43268:SF6 THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2 THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004001.1|UniProtKB=W5M8R4 W5M8R4 PTHR20973:SF0 NON-SMC ELEMENT 1-RELATED NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000006558.1|UniProtKB=W5MHR2 W5MHR2 PTHR24390:SF135 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 740 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000018344.1|UniProtKB=W5NP86 W5NP86 PTHR13976:SF83 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RNA BINDING MOTIF PROTEIN 12B-RELATED RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001282.1|UniProtKB=W5LZ91 W5LZ91 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015131.1|UniProtKB=W5NDB5 W5NDB5 PTHR23065:SF14 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 2 phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 regulation of transport#GO:0051049;regulation of localization#GO:0032879;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840;regulation of endocytosis#GO:0030100;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000018341.1|UniProtKB=W5NP83 W5NP83 PTHR11537:SF60 VOLTAGE-GATED POTASSIUM CHANNEL DELAYED-RECTIFIER POTASSIUM CHANNEL REGULATORY SUBUNIT KCNS2 potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;potassium ion transport#GO:0006813;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;action potential#GO:0001508;metal ion transport#GO:0030001 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000000484.1|UniProtKB=W5LWM5 W5LWM5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000016613.1|UniProtKB=W5NIR2 W5NIR2 PTHR24412:SF10 KELCH PROTEIN KELCH-LIKE PROTEIN 29 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002484.1|UniProtKB=W5M3F5 W5M3F5 PTHR45925:SF4 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 217 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002781.1|UniProtKB=W5M4I1 W5M4I1 PTHR10165:SF41 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;signal transduction#GO:0007165;lipid modification#GO:0030258;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004663.1|UniProtKB=W5MB23 W5MB23 PTHR15925:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S23 SMALL RIBOSOMAL SUBUNIT PROTEIN MS23 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000007456.1|UniProtKB=W5MKZ6 W5MKZ6 PTHR13817:SF44 TITIN FIBRONECTIN TYPE III DOMAIN CONTAINING 3B structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000007904.1|UniProtKB=W5MMI9 W5MMI9 PTHR10681:SF161 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-2 peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular process#GO:0009987;cellular oxidant detoxification#GO:0098869;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;cellular homeostasis#GO:0019725;response to reactive oxygen species#GO:0000302;cell redox homeostasis#GO:0045454;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;superoxide metabolic process#GO:0006801;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000006260.1|UniProtKB=W5MGQ4 W5MGQ4 PTHR15732:SF4 PROTEIN MOONRAKER PROTEIN MOONRAKER protein localization to organelle#GO:0033365;protein localization to microtubule organizing center#GO:1905508;localization#GO:0051179;protein localization to microtubule cytoskeleton#GO:0072698;intracellular protein localization#GO:0008104;protein localization to cytoskeleton#GO:0044380;macromolecule localization#GO:0033036 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002706.1|UniProtKB=W5M488 W5M488 PTHR10082:SF26 INTEGRIN BETA SUBUNIT INTEGRIN BETA-5 integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488 actin filament-based process#GO:0030029;response to transforming growth factor beta#GO:0071559;supramolecular fiber organization#GO:0097435;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;actin filament bundle assembly#GO:0051017;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cell adhesion mediated by integrin#GO:0033627;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;actin filament organization#GO:0007015;biological regulation#GO:0065007;cell migration#GO:0016477;contractile actin filament bundle assembly#GO:0030038;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cellular response to growth factor stimulus#GO:0071363;stress fiber assembly#GO:0043149;regulation of biological process#GO:0050789;actin filament bundle organization#GO:0061572;response to endogenous stimulus#GO:0009719;cellular component organization#GO:0016043;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;actomyosin structure organization#GO:0031032;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell-cell adhesion#GO:0098609;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091 signaling receptor complex#GO:0043235;cell junction#GO:0030054;integrin complex#GO:0008305;anchoring junction#GO:0070161;membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;plasma membrane#GO:0005886 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 LEPOC|Ensembl=ENSLOCG00000010944.1|UniProtKB=W5MYH3 W5MYH3 PTHR45679:SF5 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1 biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000010466.1|UniProtKB=W5MWS4 W5MWS4 PTHR46926:SF2 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 2 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 2 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016940.1|UniProtKB=W5NJY0 W5NJY0 PTHR12316:SF24 NINJURIN-RELATED NINJURIN-2 binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 cellular process#GO:0009987;cell death#GO:0008219;cell adhesion#GO:0007155;programmed cell death#GO:0012501 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000014192.1|UniProtKB=W5NA24 W5NA24 PTHR11778:SF23 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, MITOCHONDRIAL RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000003761.1|UniProtKB=W5M7X9 W5M7X9 PTHR46315:SF1 SPERMINE SYNTHASE SPERMINE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000006042.1|UniProtKB=W5MFY8 W5MFY8 PTHR46874:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;death receptor activity#GO:0005035 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;necroptotic process#GO:0070266;multicellular organismal-level homeostasis#GO:0048871;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of cell communication#GO:0010646;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;cell communication#GO:0007154;homeostasis of number of cells#GO:0048872;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;lymphocyte homeostasis#GO:0002260;regulation of apoptotic process#GO:0042981;regulation of MAPK cascade#GO:0043408;signaling#GO:0023052;response to stimulus#GO:0050896;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of cellular response to stress#GO:0080135;neuron apoptotic process#GO:0051402;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376 external side of plasma membrane#GO:0009897;membrane microdomain#GO:0098857;side of membrane#GO:0098552;membrane protein complex#GO:0098796;membrane#GO:0016020;membrane raft#GO:0045121;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 p53 pathway#P00059>FAS#G01571;FAS signaling pathway#P00020>Fas#P00612;Apoptosis signaling pathway#P00006>FAS#P00289 LEPOC|Ensembl=ENSLOCG00000013653.1|UniProtKB=W5N882 W5N882 PTHR15751:SF14 TRAFFICKING KINESIN-BINDING PROTEIN HUNTINGTIN-ASSOCIATED PROTEIN 1 myosin binding#GO:0017022;binding#GO:0005488;signaling receptor binding#GO:0005102;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;establishment of protein localization#GO:0045184;organelle transport along microtubule#GO:0072384;nervous system development#GO:0007399;establishment of vesicle localization#GO:0051650;microtubule-based transport#GO:0099111;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;cellular localization#GO:0051641;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;protein targeting#GO:0006605;establishment of organelle localization#GO:0051656;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;mitochondrion localization#GO:0051646;neurogenesis#GO:0022008;vesicle cytoskeletal trafficking#GO:0099518;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;vesicle localization#GO:0051648;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;organelle localization#GO:0051640;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;localization#GO:0051179;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848 cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;mitochondrion#GO:0005739;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;neuron projection#GO:0043005 membrane traffic protein#PC00150 Huntington disease#P00029>HAP1#P00762 LEPOC|Ensembl=ENSLOCG00000017242.1|UniProtKB=W5NL17 W5NL17 PTHR18945:SF757 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;acetylcholine receptor activity#GO:0015464;postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;neuromuscular synaptic transmission#GO:0007274;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;response to nitrogen compound#GO:1901698;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;trans-synaptic signaling#GO:0099537;modulation of chemical synaptic transmission#GO:0050804;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268 cell junction#GO:0030054;transporter complex#GO:1990351;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000006337.1|UniProtKB=W5MGZ5 W5MGZ5 PTHR24350:SF5 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE A protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 microtubule cytoskeleton organization#GO:0000226;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776;microtubule#GO:0005874;spindle microtubule#GO:0005876;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008721.1|UniProtKB=W5MQJ6 W5MQJ6 PTHR12552:SF15 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 10 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000015916.1|UniProtKB=W5NG50 W5NG50 PTHR45653:SF7 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 4 enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 cell chemotaxis#GO:0060326;response to external stimulus#GO:0009605;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;cell motility#GO:0048870;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;response to stimulus#GO:0050896;locomotion#GO:0040011;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000009101.1|UniProtKB=W5MRU0 W5MRU0 PTHR23250:SF3 DYSFERLIN-RELATED FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000011998.1|UniProtKB=W5N294 W5N294 PTHR10489:SF664 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 9 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930 cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000004672.1|UniProtKB=W5MB35 W5MB35 PTHR10271:SF25 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 8 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 response to other organism#GO:0051707;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;antiviral innate immune response#GO:0140374;cellular response to cytokine stimulus#GO:0071345;defense response to virus#GO:0051607;response to peptide#GO:1901652;response to virus#GO:0009615;immune system process#GO:0002376 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015065.1|UniProtKB=W5ND33 W5ND33 PTHR12675:SF3 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000015175.1|UniProtKB=W5NDG5 W5NDG5 PTHR19443:SF3 HEXOKINASE HEXOKINASE-4 phosphotransferase activity, alcohol group as acceptor#GO:0016773;hexokinase activity#GO:0004396;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of biological quality#GO:0065008;nucleotide metabolic process#GO:0009117;regulation of hormone secretion#GO:0046883;carbohydrate catabolic process#GO:0016052;regulation of signaling#GO:0023051;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyruvate metabolic process#GO:0006090;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;monocarboxylic acid metabolic process#GO:0032787;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;glucose homeostasis#GO:0042593;ADP catabolic process#GO:0046032;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;regulation of insulin secretion#GO:0050796;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nucleoside triphosphate metabolic process#GO:0009141;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;regulation of cellular process#GO:0050794;nucleoside phosphate catabolic process#GO:1901292;regulation of protein secretion#GO:0050708;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular homeostasis#GO:0019725;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;biological regulation#GO:0065007;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;regulation of secretion by cell#GO:1903530;regulation of protein localization#GO:0032880;intracellular glucose homeostasis#GO:0001678;oxoacid metabolic process#GO:0043436;pyridine nucleotide catabolic process#GO:0019364;regulation of protein transport#GO:0051223;small molecule metabolic process#GO:0044281;carbohydrate homeostasis#GO:0033500;ribonucleoside diphosphate metabolic process#GO:0009185;regulation of hormone levels#GO:0010817;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;regulation of localization#GO:0032879;regulation of transport#GO:0051049;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;chemical homeostasis#GO:0048878;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;regulation of establishment of protein localization#GO:0070201;cellular respiration#GO:0045333;regulation of secretion#GO:0051046;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate metabolic process#GO:0006753;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;glucose 6-phosphate metabolic process#GO:0051156;catabolic process#GO:0009056;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;intracellular chemical homeostasis#GO:0055082;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655 side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic side of membrane#GO:0098562;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011554.1|UniProtKB=W5N0N9 W5N0N9 PTHR14167:SF64 SH3 DOMAIN-CONTAINING SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor complex adaptor activity#GO:0030159;signaling adaptor activity#GO:0035591 organelle organization#GO:0006996;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-substrate adhesion#GO:0031589;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008159.1|UniProtKB=W5MNE4 W5MNE4 ELOF1 PTHR20934:SF0 TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000011470.1|UniProtKB=W5N0C8 W5N0C8 PTHR15863:SF2 MRN COMPLEX-INTERACTING PROTEIN MRN COMPLEX-INTERACTING PROTEIN chromatin binding#GO:0003682;binding#GO:0005488 response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;cellular response to stress#GO:0033554;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013820.1|UniProtKB=W5N8T1 W5N8T1 PTHR10846:SF36 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 1 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;antiporter activity#GO:0015297;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261 negative regulation of biological process#GO:0048519;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological process#GO:0050789;calcium ion homeostasis#GO:0055074;positive regulation of synaptic transmission#GO:0050806;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;positive regulation of signaling#GO:0023056;negative regulation of cell communication#GO:0010648;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of trans-synaptic signaling#GO:0099177;monoatomic cation transmembrane transport#GO:0098655;chemical homeostasis#GO:0048878;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;metal ion transport#GO:0030001;homeostatic process#GO:0042592;modulation of chemical synaptic transmission#GO:0050804;monoatomic cation transport#GO:0006812;localization#GO:0051179;positive regulation of cellular process#GO:0048522;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of synaptic plasticity#GO:0048167;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000017529.1|UniProtKB=W5NLX5 W5NLX5 PTHR11863:SF106 STEROL DESATURASE CHOLESTEROL 25-HYDROXYLASE-LIKE PROTEIN 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238;secondary alcohol biosynthetic process#GO:1902653;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000009201.1|UniProtKB=W5MS61 W5MS61 PTHR31740:SF2 CENTROMERE PROTEIN L CENTROMERE PROTEIN L LEPOC|Ensembl=ENSLOCG00000015892.1|UniProtKB=W5NG13 W5NG13 PTHR11214:SF219 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000018017.1|UniProtKB=W5NNA9 W5NNA9 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 14A ISOFORM X1-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011718.1|UniProtKB=W5N197 W5N197 PTHR12924:SF2 TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA ISOFORM X1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006313.1|UniProtKB=W5MGY7 W5MGY7 PTHR10980:SF8 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 3 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000004267.1|UniProtKB=W5M9R1 W5M9R1 PTHR14248:SF32 CYCLIN Y, ISOFORM A CYCLIN-Y-LIKE PROTEIN 1 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006288.1|UniProtKB=W5MGT7 W5MGT7 PTHR14969:SF17 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE INACTIVE PHOSPHOLIPID PHOSPHATASE 7 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;dephosphorylation#GO:0016311;primary metabolic process#GO:0044238;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839 nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004779.1|UniProtKB=W5MBH3 W5MBH3 PTHR21146:SF3 MEF2B PROTEIN BLOC-1-RELATED COMPLEX SUBUNIT 8 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 p38 MAPK pathway#P05918>MEF#P06023 LEPOC|Ensembl=ENSLOCG00000009213.1|UniProtKB=W5MS78 W5MS78 PTHR11086:SF14 DEOXYCYTIDYLATE DEAMINASE-RELATED DCTP DEAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 deaminase#PC00088;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013002.1|UniProtKB=W5N5V6 W5N5V6 PTHR23343:SF31 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 4 structural molecule activity#GO:0005198;protein binding#GO:0005515;enzyme binding#GO:0019899;extracellular matrix structural constituent#GO:0005201;binding#GO:0005488 multicellular organismal process#GO:0032501;regulation of reproductive process#GO:2000241;reproductive process#GO:0022414;fertilization#GO:0009566;biological regulation#GO:0065007;single fertilization#GO:0007338;negative regulation of biological process#GO:0048519;cellular process#GO:0009987;regulation of biological process#GO:0050789;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988;sperm-egg recognition#GO:0035036;cell activation#GO:0001775;cell recognition#GO:0008037;sexual reproduction#GO:0019953 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011648.1|UniProtKB=W5N100 W5N100 PTHR24336:SF9 TRANSCRIPTION FACTOR LBX TRANSCRIPTION FACTOR LBX1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004640.1|UniProtKB=W5MAZ7 W5MAZ7 PTHR15617:SF1 TRANSCRIPTION FACTOR GIBBIN TRANSCRIPTION FACTOR GIBBIN LEPOC|Ensembl=ENSLOCG00000011070.1|UniProtKB=W5MYY9 W5MYY9 PTHR18952:SF283 CARBONIC ANHYDRASE CARBONIC ANHYDRASE XB-RELATED metabolite interconversion enzyme#PC00262;dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000004008.1|UniProtKB=W5M8S8 W5M8S8 PTHR10689:SF9 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 PROSTAGLANDIN E SYNTHASE catalytic activity#GO:0003824;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;prostaglandin metabolic process#GO:0006693;oxoacid metabolic process#GO:0043436;unsaturated fatty acid biosynthetic process#GO:0006636;fatty acid biosynthetic process#GO:0006633;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;icosanoid metabolic process#GO:0006690;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016663.1|UniProtKB=W5NIX5 W5NIX5 PTHR45815:SF3 PROTEIN DISULFIDE-ISOMERASE A6 PROTEIN DISULFIDE-ISOMERASE A6 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012091.1|UniProtKB=W5N2N0 W5N2N0 PTHR45615:SF44 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-13 microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 system process#GO:0003008;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;muscle contraction#GO:0006936 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000013141.1|UniProtKB=W5N6C8 W5N6C8 PTHR23176:SF104 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 27 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000003943.1|UniProtKB=W5M8J9 W5M8J9 PTHR20921:SF0 TRANSMEMBRANE PROTEIN 222 TRANSMEMBRANE PROTEIN 222 LEPOC|Ensembl=ENSLOCG00000007009.1|UniProtKB=W5MJC8 W5MJC8 PTHR23429:SF7 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GDH_6PGL ENDOPLASMIC BIFUNCTIONAL PROTEIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;glucose-6-phosphate dehydrogenase activity#GO:0004345;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;glucose metabolic process#GO:0006006;generation of precursor metabolites and energy#GO:0006091;pentose-phosphate shunt, oxidative branch#GO:0009051;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;nucleobase-containing compound metabolic process#GO:0006139;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;hexose metabolic process#GO:0019318;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000011022.1|UniProtKB=W5MYR8 W5MYR8 PTHR13137:SF6 DC11 ACN9 HOMOLOG SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 3, MITOCHONDRIAL cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex II assembly#GO:0034553;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010021.1|UniProtKB=W5MV46 W5MV46 PTHR13218:SF8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11 protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 general transcription factor#PC00259;RNA metabolism protein#PC00031 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 LEPOC|Ensembl=ENSLOCG00000009892.1|UniProtKB=W5MUM8 W5MUM8 PTHR24340:SF34 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-3.2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009424.1|UniProtKB=W5MT06 W5MT06 PTHR46049:SF4 AGAP003327-PA UNCONVENTIONAL MYOSIN-X cellular developmental process#GO:0048869;developmental growth#GO:0048589;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;anatomical structure development#GO:0048856;system development#GO:0048731;developmental cell growth#GO:0048588;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell growth#GO:0016049;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;axon extension#GO:0048675;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;neuron development#GO:0048666;axonogenesis#GO:0007409;developmental growth involved in morphogenesis#GO:0060560;neuron projection extension#GO:1990138;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;site of polarized growth#GO:0030427;growth cone#GO:0030426;axonal growth cone#GO:0044295;axon#GO:0030424 LEPOC|Ensembl=ENSLOCG00000002889.1|UniProtKB=W5M4U4 W5M4U4 PTHR42944:SF1 ADENINE DNA GLYCOSYLASE ADENINE DNA GLYCOSYLASE DNA binding#GO:0003677;hydrolase activity#GO:0016787;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;damaged DNA binding#GO:0003684 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mismatch repair#GO:0006298;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA glycosylase#PC00010;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000017631.1|UniProtKB=W5NM77 W5NM77 PTHR24410:SF8 HL07962P-RELATED PEROXISOMAL BIOSIS FACTOR 11 GAMMA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000012530.1|UniProtKB=W5N476 W5N476 PTHR15941:SF11 MYOZENIN MYOZENIN-1 molecular condensate scaffold activity#GO:0140693;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;striated muscle tissue development#GO:0014706;cellular anatomical entity morphogenesis#GO:0032989;muscle organ development#GO:0007517;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;cell development#GO:0048468;actomyosin structure organization#GO:0031032;response to stimulus#GO:0050896;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;system process#GO:0003008;cellular developmental process#GO:0048869;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;skeletal muscle tissue development#GO:0007519;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cellular response to stimulus#GO:0051716;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001 cytoskeleton#GO:0005856;I band#GO:0031674;sarcomere#GO:0030017;membraneless organelle#GO:0043228;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000015281.1|UniProtKB=W5NDU7 W5NDU7 PTHR12301:SF14 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM AND SH3 DOMAIN-CONTAINING 3 positive regulation of leukocyte activation#GO:0002696;regulation of B cell proliferation#GO:0030888;regulation of leukocyte proliferation#GO:0070663;positive regulation of mononuclear cell proliferation#GO:0032946;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of mononuclear cell proliferation#GO:0032944;regulation of B cell activation#GO:0050864;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;positive regulation of cell population proliferation#GO:0008284;regulation of leukocyte activation#GO:0002694;regulation of lymphocyte activation#GO:0051249;positive regulation of adaptive immune response#GO:0002821;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of leukocyte proliferation#GO:0070665;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cell activation#GO:0050867;positive regulation of immune effector process#GO:0002699;positive regulation of response to stimulus#GO:0048584;regulation of lymphocyte proliferation#GO:0050670;regulation of immune response#GO:0050776;positive regulation of lymphocyte proliferation#GO:0050671;positive regulation of biosynthetic process#GO:0009891;positive regulation of lymphocyte activation#GO:0051251;regulation of cell population proliferation#GO:0042127;regulation of immune effector process#GO:0002697;positive regulation of B cell proliferation#GO:0030890;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 LEPOC|Ensembl=ENSLOCG00000015963.1|UniProtKB=W5NG97 W5NG97 PTHR15835:SF6 NUCLEAR-INTERACTING PARTNER OF ALK ZINC FINGER C3HC-TYPE PROTEIN 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000010585.1|UniProtKB=W5MX72 W5MX72 PTHR11827:SF47 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 7 symporter activity#GO:0015293;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;chloride transport#GO:0006821 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000006956.1|UniProtKB=W5MJ60 W5MJ60 PTHR46568:SF1 ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000017353.1|UniProtKB=W5NLE9 W5NLE9 PTHR31703:SF2 UPF0669 PROTEIN C6ORF120 UPF0669 PROTEIN C6ORF120 LEPOC|Ensembl=ENSLOCG00000011035.1|UniProtKB=W5MYT3 W5MYT3 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011394.1|UniProtKB=W5N059 W5N059 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000735.1|UniProtKB=W5LXF6 W5LXF6 PTHR12281:SF10 RP42 RELATED DCN1-LIKE PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787 positive regulation of protein metabolic process#GO:0051247;regulation of protein modification process#GO:0031399;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009082.1|UniProtKB=W5MRR2 W5MRR2 PTHR45894:SF1 RNA-BINDING PROTEIN 8A RNA-BINDING PROTEIN 8A nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000008834.1|UniProtKB=W5MQU0 W5MQU0 PTHR11211:SF13 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;neuron differentiation#GO:0030182 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000000001.1|UniProtKB=W5LV44 W5LV44 PTHR19300:SF33 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 3 galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000000871.1|UniProtKB=W5LY02 W5LY02 PTHR45615:SF1 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-7 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;actin filament binding#GO:0051015;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146 circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;system development#GO:0048731;muscle system process#GO:0003012;heart process#GO:0003015;circulatory system development#GO:0072359;actin-mediated cell contraction#GO:0070252;striated muscle contraction#GO:0006941;developmental process#GO:0032502;muscle contraction#GO:0006936;multicellular organism development#GO:0007275;animal organ development#GO:0048513;heart contraction#GO:0060047;system process#GO:0003008;cellular process#GO:0009987;actin filament-based movement#GO:0030048;blood circulation#GO:0008015;heart development#GO:0007507;multicellular organismal process#GO:0032501 actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 LEPOC|Ensembl=ENSLOCG00000000300.1|UniProtKB=W5LW64 W5LW64 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002276.1|UniProtKB=W5M2Q0 W5M2Q0 PTHR15446:SF2 UROPLAKIN III UROPLAKIN-3B-LIKE PROTEIN 1-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004198.1|UniProtKB=W5M9F6 W5M9F6 PTHR46037:SF7 PROTEIN ENHANCER OF SEVENLESS 2B SRC-LIKE-ADAPTER 2 growth factor receptor binding#GO:0070851;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;regulation of intracellular signal transduction#GO:1902531 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000002756.1|UniProtKB=W5M4D3 W5M4D3 PTHR37557:SF4 115 KDA PROTEIN IN TYPE-1 RETROTRANSPOSABLE ELEMENT R1DM-LIKE PROTEIN-RELATED-RELATED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000006285.1|UniProtKB=W5MGT1 W5MGT1 PTHR13097:SF7 TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TFIIE#P00666;General transcription regulation#P00023>TFIIEalpha#P00669;Transcription regulation by bZIP transcription factor#P00055>TFIIEalpha#P01398;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395 LEPOC|Ensembl=ENSLOCG00000009816.1|UniProtKB=W5MUD2 W5MUD2 PTHR24133:SF16 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 9 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014044.1|UniProtKB=W5N9K2 W5N9K2 PTHR23257:SF717 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017322.1|UniProtKB=W5NLB8 W5NLB8 PTHR10704:SF36 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 amino sugar metabolic process#GO:0006040;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011503.1|UniProtKB=W5N0K2 W5N0K2 PTHR45703:SF12 DYNEIN HEAVY CHAIN DYNEIN AXONEMAL HEAVY CHAIN 11 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000017523.1|UniProtKB=W5NLW9 W5NLW9 PTHR24156:SF1 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 34B LEPOC|Ensembl=ENSLOCG00000011266.1|UniProtKB=W5MZM9 W5MZM9 PTHR44500:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003087.1|UniProtKB=W5M5H6 W5M5H6 PTHR19818:SF69 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000007365.1|UniProtKB=W5MKN6 W5MKN6 PTHR13944:SF20 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;intracellular signaling cassette#GO:0141124;cytoskeleton organization#GO:0007010;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435;regulation of intracellular signal transduction#GO:1902531;actin filament-based process#GO:0030029;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;actin cytoskeleton organization#GO:0030036;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;ruffle membrane#GO:0032587;ruffle#GO:0001726;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013362.1|UniProtKB=W5N767 W5N767 PTHR13140:SF313 MYOSIN UNCONVENTIONAL MYOSIN-VC cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 actin cytoskeleton#GO:0015629;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000017848.1|UniProtKB=W5NMU2 W5NMU2 PTHR22796:SF14 URG4-RELATED INTERFERON-INDUCED VERY LARGE GTPASE 1-RELATED LEPOC|Ensembl=ENSLOCG00000003157.1|UniProtKB=W5M5R9 W5M5R9 PTHR19143:SF156 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-1 receptor tyrosine kinase binding#GO:0030971;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;signaling#GO:0023052;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;tube development#GO:0035295;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 intercellular signal molecule#PC00207 Angiogenesis#P00005>Ang-1#P00248 LEPOC|Ensembl=ENSLOCG00000014849.1|UniProtKB=W5NCC3 W5NCC3 PTHR24169:SF18 NUCLEAR FACTOR NF-KAPPA-B PROTEIN TRANSCRIPTION FACTOR RELB cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 immune system process#GO:0002376;response to peptide#GO:1901652;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;non-canonical NF-kappaB signal transduction#GO:0038061;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;intracellular signaling cassette#GO:0141124;defense response to other organism#GO:0098542;positive regulation of macromolecule metabolic process#GO:0010604;response to cytokine#GO:0034097;response to chemical#GO:0042221;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;defense response#GO:0006952;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;innate immune response#GO:0045087;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;response to other organism#GO:0051707;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;canonical NF-kappaB signal transduction#GO:0007249;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Apoptosis signaling pathway#P00006>NFkappaB#P00297 LEPOC|Ensembl=ENSLOCG00000002460.1|UniProtKB=W5M3I6 W5M3I6 PTHR10648:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 LEPOC|Ensembl=ENSLOCG00000000837.1|UniProtKB=W5LXS8 W5LXS8 PTHR23227:SF88 BUCENTAUR RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007137.1|UniProtKB=W5MJT2 W5MJT2 PTHR11561:SF18 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP] transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;lyase activity#GO:0016829;metal ion binding#GO:0046872;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 response to carbohydrate#GO:0009743;response to monosaccharide#GO:0034284;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;liver development#GO:0001889;glucose homeostasis#GO:0042593;multicellular organism development#GO:0007275;cellular response to steroid hormone stimulus#GO:0071383;alcohol metabolic process#GO:0006066;carbohydrate biosynthetic process#GO:0016051;cellular response to lipid#GO:0071396;alcohol biosynthetic process#GO:0046165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;anatomical structure development#GO:0048856;response to steroid hormone#GO:0048545;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular homeostasis#GO:0019725;cellular response to insulin stimulus#GO:0032869;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;response to peptide hormone#GO:0043434;epithelium development#GO:0060429;response to glucose#GO:0009749;epithelial cell differentiation#GO:0030855;multicellular organismal process#GO:0032501;intracellular glucose homeostasis#GO:0001678;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;small molecule metabolic process#GO:0044281;carbohydrate homeostasis#GO:0033500;response to endogenous stimulus#GO:0009719;response to hexose#GO:0009746;carboxylic acid metabolic process#GO:0019752;animal organ development#GO:0048513;glucose metabolic process#GO:0006006;chemical homeostasis#GO:0048878;cellular response to glucose stimulus#GO:0071333;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;response to chemical#GO:0042221;response to lipid#GO:0033993;gluconeogenesis#GO:0006094;response to stress#GO:0006950;response to hormone#GO:0009725;system development#GO:0048731;response to nitrogen compound#GO:1901698;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;cellular response to peptide hormone stimulus#GO:0071375;hexose biosynthetic process#GO:0019319;response to starvation#GO:0042594;intracellular chemical homeostasis#GO:0055082;cellular developmental process#GO:0048869;developmental process#GO:0032502;small molecule biosynthetic process#GO:0044283;cellular response to nitrogen compound#GO:1901699;tissue development#GO:0009888;response to nutrient levels#GO:0031667 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 Pyruvate metabolism#P02772>Phosphoenolpyruvate Carboxykinase#P03135 LEPOC|Ensembl=ENSLOCG00000001750.1|UniProtKB=W5M0W3 W5M0W3 PTHR48011:SF4 CCR4-NOT TRANSCRIPTIONAL COMPLEX SUBUNIT CAF120-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19 catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 LEPOC|Ensembl=ENSLOCG00000008223.1|UniProtKB=W5MNN0 W5MNN0 PTHR24044:SF467 NOTCH LIGAND FAMILY MEMBER DELTA AND NOTCH-LIKE EPIDERMAL GROWTH FACTOR-RELATED RECEPTOR protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003495.1|UniProtKB=W5M6Z1 W5M6Z1 PTHR46160:SF9 ALPHA-TECTORIN-RELATED DENDRITE EXTENSION DEFECTIVE PROTEIN 1-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000012967.1|UniProtKB=W5N5R1 W5N5R1 PTHR11461:SF399 SERINE PROTEASE INHIBITOR, SERPIN LEUKOCYTE ELASTASE INHIBITOR-RELATED enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000003544.1|UniProtKB=W5M730 W5M730 PTHR28498:SF1 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000017551.1|UniProtKB=W5NLZ7 W5NLZ7 PTHR24241:SF127 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 22 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016457.1|UniProtKB=W5NI75 W5NI75 PTHR22958:SF43 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1 hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 glycerophospholipid catabolic process#GO:0046475;organophosphate catabolic process#GO:0046434;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000001620.1|UniProtKB=W5M0F9 W5M0F9 PTHR27001:SF118 OS01G0253100 PROTEIN INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 ISOFORM X1 protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000011929.1|UniProtKB=W5N207 W5N207 PTHR12964:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013125.1|UniProtKB=W5N6A7 W5N6A7 PTHR12817:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;cis-Golgi network#GO:0005801;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008036.1|UniProtKB=W5MN00 W5MN00 PTHR34833:SF1 GENE, 17359-RELATED PROTEIN SPMIP2 LEPOC|Ensembl=ENSLOCG00000005518.1|UniProtKB=W5ME53 W5ME53 PTHR10704:SF60 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 3 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 amino sugar metabolic process#GO:0006040;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;sulfur compound metabolic process#GO:0006790;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000016470.1|UniProtKB=W5NI89 W5NI89 PTHR15922:SF2 NEUROBLASTOMA-AMPLIFIED SEQUENCE NBAS SUBUNIT OF NRZ TETHERING COMPLEX protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;vesicle tethering complex#GO:0099023;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000017271.1|UniProtKB=W5NL54 W5NL54 PTHR11132:SF515 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER D3 active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005369.1|UniProtKB=W5MDL3 W5MDL3 PTHR15600:SF43 SACSIN HEPN DOMAIN-CONTAINING PROTEIN Hsp70 protein binding#GO:0030544;protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 LEPOC|Ensembl=ENSLOCG00000009610.1|UniProtKB=W5MTN5 W5MTN5 PTHR45620:SF24 PDF RECEPTOR-LIKE PROTEIN-RELATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002332.1|UniProtKB=W5M2Z4 W5M2Z4 PTHR44163:SF1 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;rRNA metabolic process#GO:0016072;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;rRNA processing#GO:0006364;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;t-UTP complex#GO:0034455;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000009940.1|UniProtKB=W5MUU2 W5MUU2 PTHR47730:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 29 SMALL INTEGRAL MEMBRANE PROTEIN 29 LEPOC|Ensembl=ENSLOCG00000013372.1|UniProtKB=W5N772 W5N772 PTHR48051:SF64 FAMILY NOT NAMED LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 4 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002567.1|UniProtKB=W5M3S4 W5M3S4 PTHR24271:SF100 KALLIKREIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000014183.1|UniProtKB=W5NA20 W5NA20 PTHR19302:SF27 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 4 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000017122.1|UniProtKB=W5NKK0 W5NKK0 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011267.1|UniProtKB=W5MZN6 W5MZN6 PTHR23172:SF34 AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED CYCLIN-G-ASSOCIATED KINASE protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component disassembly#GO:0022411;receptor-mediated endocytosis#GO:0006898;protein-containing complex organization#GO:0043933;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015489.1|UniProtKB=W5NEK3 W5NEK3 PTHR13326:SF31 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE 7 HOMOLOG isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;RNA modification#GO:0009451;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000014869.1|UniProtKB=W5NCF8 W5NCF8 PTHR21646:SF115 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000003671.1|UniProtKB=W5M7M9 W5M7M9 PTHR44099:SF3 RABCONNECTIN-3B, ISOFORM A WD REPEAT-CONTAINING PROTEIN 7 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014463.1|UniProtKB=W5NAZ1 W5NAZ1 PTHR10270:SF283 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-19A-RELATED sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000003860.1|UniProtKB=W5M899 W5M899 PTHR28595:SF1 39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML54 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006120.1|UniProtKB=W5MG88 W5MG88 PTHR23098:SF7 AGAP001331-PA-RELATED NUCLEAR APOPTOSIS-INDUCING FACTOR 1 LEPOC|Ensembl=ENSLOCG00000008615.1|UniProtKB=W5MQ13 W5MQ13 PTHR12937:SF0 VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 catabolic process#GO:0009056;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of protein localization to vacuole#GO:0072666;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;cellular localization#GO:0051641;protein transport#GO:0015031;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;endosomal transport#GO:0016197;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886 vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;ESCRT I complex#GO:0000813;membrane#GO:0016020;cytosol#GO:0005829;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003861.1|UniProtKB=W5M8A6 W5M8A6 PTHR44054:SF2 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE NADPH-DEPENDENT QUINONE OXIDOREDUCTASE VAT1L-RELATED Huntington disease#P00029>PIG3#G01535 LEPOC|Ensembl=ENSLOCG00000017588.1|UniProtKB=W5NM34 W5NM34 PTHR11786:SF8 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE 1 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000017287.1|UniProtKB=W5NL76 W5NL76 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016330.1|UniProtKB=W5NHP9 W5NHP9 PTHR11805:SF2 CYSTEINE-RICH PDZ-BINDING PROTEIN CYSTEINE-RICH PDZ-BINDING PROTEIN protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 dendrite#GO:0030425;dendritic tree#GO:0097447;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477 LEPOC|Ensembl=ENSLOCG00000001265.1|UniProtKB=W5LZ74 W5LZ74 PTHR34488:SF1 SI:CH211-245H14.1-RELATED SI:CH211-245H14.1-RELATED LEPOC|Ensembl=ENSLOCG00000009063.1|UniProtKB=W5MRN4 W5MRN4 PTHR10333:SF85 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 1 chromatin-protein adaptor activity#GO:0140463;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017708.1|UniProtKB=W5NMF4 W5NMF4 PTHR10155:SF21 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 4 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to chemical#GO:0042221;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 LEPOC|Ensembl=ENSLOCG00000002168.1|UniProtKB=W5M2D1 W5M2D1 PTHR13723:SF20 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 13 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000009998.1|UniProtKB=W5MV18 W5MV18 PTHR15959:SF0 SYNTAXIN-18 SYNTAXIN-18 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 membrane traffic protein#PC00150;SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000017649.1|UniProtKB=W5NM95 W5NM95 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009722.1|UniProtKB=W5MU14 W5MU14 PTHR24238:SF81 G-PROTEIN COUPLED RECEPTOR GASTRIN_CHOLECYSTOKININ TYPE B RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015158.1|UniProtKB=W5NDE8 W5NDE8 PTHR46489:SF3 STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL cholesterol binding#GO:0015485;lipid binding#GO:0008289;steroid binding#GO:0005496;alcohol binding#GO:0043178;sterol binding#GO:0032934;small molecule binding#GO:0036094;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;intracellular sterol transport#GO:0032366;regulation of lipid metabolic process#GO:0019216;lipid localization#GO:0010876;cellular localization#GO:0051641;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;cholesterol transport#GO:0030301;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of steroid biosynthetic process#GO:0050810;regulation of lipid biosynthetic process#GO:0046890;lipid transport#GO:0006869;biological regulation#GO:0065007;intracellular transport#GO:0046907;transport#GO:0006810;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;sterol transport#GO:0015918 LEPOC|Ensembl=ENSLOCG00000000012.1|UniProtKB=W5LV61 W5LV61 PTHR10644:SF27 DNA REPAIR/RNA PROCESSING CPSF FAMILY DNA DAMAGE-BINDING PROTEIN 1 modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;proteasomal protein catabolic process#GO:0010498;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000010123.1|UniProtKB=W5MVJ2 W5MVJ2 PTHR10694:SF3 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5B catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;protein demethylase activity#GO:0140457;dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000001074.1|UniProtKB=W5LYJ9 W5LYJ9 PTHR15663:SF4 COMM DOMAIN-CONTAINING PROTEIN 9 COMM DOMAIN-CONTAINING PROTEIN 9 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000012660.1|UniProtKB=W5N4M2 W5N4M2 PTHR21290:SF24 SPHINGOMYELIN SYNTHETASE PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity#GO:0016740;catalytic activity#GO:0003824 sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;ceramide metabolic process#GO:0006672 plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 LEPOC|Ensembl=ENSLOCG00000002878.1|UniProtKB=W5M4T1 W5M4T1 PTHR11380:SF17 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13 transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000006626.1|UniProtKB=W5MHZ8 W5MHZ8 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014203.1|UniProtKB=W5NA49 W5NA49 PTHR12750:SF11 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 nucleotide kinase#PC00172;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000016714.1|UniProtKB=W5NJ42 W5NJ42 PTHR28603:SF1 TRANSMEMBRANE PROTEIN 243 TRANSMEMBRANE PROTEIN 243 LEPOC|Ensembl=ENSLOCG00000017877.1|UniProtKB=W5NMX1 W5NMX1 PTHR10489:SF959 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 6A immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;response to chemical#GO:0042221;taxis#GO:0042330;cell migration#GO:0016477;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;immune response#GO:0006955;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;chemotaxis#GO:0006935;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;locomotion#GO:0040011;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011058.1|UniProtKB=W5MYW7 W5MYW7 PTHR16484:SF4 PARTITIONING DEFECTIVE 3 RELATED PARTITIONING DEFECTIVE 3 HOMOLOG B phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;apical part of cell#GO:0045177;apical junction complex#GO:0043296;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;cell-cell junction#GO:0005911;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000000632.1|UniProtKB=W5LX40 W5LX40 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014880.1|UniProtKB=W5NCG8 W5NCG8 PTHR18952:SF19 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 12 catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 monoatomic ion homeostasis#GO:0050801;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592 basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical part of cell#GO:0045177 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000302.1|UniProtKB=W5LW22 W5LW22 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005590.1|UniProtKB=W5MEE8 W5MEE8 PTHR46711:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 histone H3K36 methyltransferase activity#GO:0046975;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000014476.1|UniProtKB=W5NB10 W5NB10 PTHR23248:SF57 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE intramembrane lipid carrier activity#GO:0140303;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128 cellular process#GO:0009987;macromolecule localization#GO:0033036;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;endomembrane system organization#GO:0010256;phospholipid transport#GO:0015914;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component organization#GO:0016043;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011474.1|UniProtKB=W5N0E2 W5N0E2 PTHR11075:SF54 PEPTIDE CHAIN RELEASE FACTOR LARGE RIBOSOMAL SUBUNIT PROTEIN ML62 catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;translation factor activity#GO:0180051;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;carboxylic ester hydrolase activity#GO:0052689 translation release factor#PC00225 LEPOC|Ensembl=ENSLOCG00000015769.1|UniProtKB=W5NFK4 W5NFK4 PTHR46944:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 33 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 33 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000016396.1|UniProtKB=W5NHZ0 W5NHZ0 PTHR11528:SF79 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-BETA-RELATED heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ATP-dependent activity#GO:0140657;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;binding#GO:0005488;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 metabolic process#GO:0008152;protein stabilization#GO:0050821;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of protein stability#GO:0031647;response to stress#GO:0006950;response to heat#GO:0009408;cellular response to heat#GO:0034605;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;protein maturation#GO:0051604;gene expression#GO:0010467;cellular response to stress#GO:0033554;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;protein folding#GO:0006457;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Hsp90 family chaperone#PC00028;chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016497.1|UniProtKB=W5NIB7 W5NIB7 PTHR45813:SF4 IG-LIKE DOMAIN-CONTAINING PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR F5 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017256.1|UniProtKB=W5NL35 W5NL35 PTHR10383:SF15 SERINE INCORPORATOR SERINE INCORPORATOR 1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008950.1|UniProtKB=W5MR96 W5MR96 PTHR23320:SF178 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 8-RELATED transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000018169.1|UniProtKB=W5NNR1 W5NNR1 PTHR24225:SF83 CHEMOTACTIC RECEPTOR CHEMERIN-LIKE RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375 regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of biological quality#GO:0065008;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;immune response-activating signaling pathway#GO:0002757;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of immune response#GO:0050778 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000900.1|UniProtKB=W5LXZ3 W5LXZ3 PTHR14083:SF2 YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN PROTEIN YIF1A intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016598.1|UniProtKB=W5NIP0 W5NIP0 PTHR12358:SF116 SPHINGOSINE KINASE ACYLGLYCEROL KINASE, MITOCHONDRIAL lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingoid biosynthetic process#GO:0046520;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015330.1|UniProtKB=W5NE05 W5NE05 PTHR10369:SF3 60S RIBOSOMAL PROTEIN L36A/L44 RIBOSOMAL PROTEIN L36A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000017345.1|UniProtKB=W5NLE1 W5NLE1 PTHR24231:SF35 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010777.1|UniProtKB=W5MXU2 W5MXU2 PTHR46263:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 7 ARMADILLO REPEAT-CONTAINING PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000001033.1|UniProtKB=W5LYI6 W5LYI6 PTHR23169:SF10 ENVOPLAKIN PERIPLAKIN cellular process#GO:0009987;response to stress#GO:0006950;response to wounding#GO:0009611;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;response to stimulus#GO:0050896;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament-based process#GO:0045103;wound healing#GO:0042060;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane#GO:0016020 intermediate filament#PC00129;intermediate filament binding protein#PC00130 LEPOC|Ensembl=ENSLOCG00000015813.1|UniProtKB=W5NFQ9 W5NFQ9 PTHR11380:SF16 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION PROTEIN SPT3 HOMOLOG transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000016150.1|UniProtKB=W5NGY9 W5NGY9 PTHR10173:SF56 METHIONINE SULFOXIDE REDUCTASE METHIONINE-R-SULFOXIDE REDUCTASE B3 oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000016868.1|UniProtKB=W5NJP8 W5NJP8 PTHR23331:SF5 CXYORF1 WAS PROTEIN FAMILY HOMOLOG 2-RELATED transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;exocytosis#GO:0006887;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;actin filament-based process#GO:0030029;secretion by cell#GO:0032940;supramolecular fiber organization#GO:0097435;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;cellular component organization#GO:0016043;export from cell#GO:0140352;cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;recycling endosome#GO:0055037;intracellular organelle#GO:0043229;endosome#GO:0005768 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018071.1|UniProtKB=W5NNG3 W5NNG3 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED SI:DKEYP-69E1.8 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000014289.1|UniProtKB=W5NAD4 W5NAD4 PTHR24068:SF33 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015731.1|UniProtKB=W5NFF7 W5NFF7 PTHR45726:SF7 LEUKOTRIENE A-4 HYDROLASE LEUKOTRIENE A-4 HYDROLASE exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ether hydrolase activity#GO:0016803;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177 peptide metabolic process#GO:0006518;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;icosanoid metabolic process#GO:0006690;biosynthetic process#GO:0009058;icosanoid biosynthetic process#GO:0046456;carboxylic acid metabolic process#GO:0019752;peptide catabolic process#GO:0043171;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000002500.1|UniProtKB=W5M3I2 W5M3I2 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015295.1|UniProtKB=W5NDV9 W5NDV9 PTHR13217:SF6 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 LEPOC|Ensembl=ENSLOCG00000007399.1|UniProtKB=W5MKS3 W5MKS3 OLA1 PTHR23305:SF11 OBG GTPASE FAMILY OBG-LIKE ATPASE 1 ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000010340.1|UniProtKB=W5MWC3 W5MWC3 PTHR46189:SF3 LD41958P WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 2 positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;positive regulation of fat cell differentiation#GO:0045600 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000003214.1|UniProtKB=W5M672 W5M672 PTHR16166:SF141 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13D phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215 cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;lipid transport#GO:0006869;transport#GO:0006810;metabolic process#GO:0008152;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;catabolic process#GO:0009056;lipid localization#GO:0010876;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179 cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;mitochondrion#GO:0005739;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;outer membrane#GO:0019867;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007364.1|UniProtKB=W5MKL8 W5MKL8 PTHR48016:SF31 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 8 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Toll receptor signaling pathway#P00054>TPL2#P01364 LEPOC|Ensembl=ENSLOCG00000013305.1|UniProtKB=W5N6Z3 W5N6Z3 PTHR24291:SF43 CYTOCHROME P450 FAMILY 4 AROMATASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 anatomical structure development#GO:0048856;reproductive system development#GO:0061458;system development#GO:0048731;female gonad development#GO:0008585;animal gross anatomical part developmental process#GO:0160108;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;reproductive process#GO:0022414;reproductive structure development#GO:0048608;developmental process involved in reproduction#GO:0003006;animal organ development#GO:0048513;multicellular organism development#GO:0007275;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;response to lipid#GO:0033993;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to estradiol#GO:0032355;gonad development#GO:0008406;sex differentiation#GO:0007548 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 Androgen/estrogene/progesterone biosynthesis#P02727>Aromatase#P02828 LEPOC|Ensembl=ENSLOCG00000016964.1|UniProtKB=W5NK18 W5NK18 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000003587.1|UniProtKB=W5M7B3 W5M7B3 ABR PTHR23182:SF5 BREAKPOINT CLUSTER REGION PROTEIN BCR ACTIVE BREAKPOINT CLUSTER REGION-RELATED PROTEIN enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056 cell junction#GO:0030054;postsynaptic density#GO:0014069;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;asymmetric synapse#GO:0032279;organelle#GO:0043226;glutamatergic synapse#GO:0098978;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794 G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000015696.1|UniProtKB=W5NFB3 W5NFB3 PTHR20916:SF26 CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096 LEPOC|Ensembl=ENSLOCG00000011004.1|UniProtKB=W5MYP0 W5MYP0 PTHR16771:SF0 26 PROTEASOME COMPLEX SUBUNIT DSS1 26S PROTEASOME COMPLEX SUBUNIT SEM1 double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 intracellular protein-containing complex#GO:0140535;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000488.1|UniProtKB=W5LWM7 W5LWM7 PTHR21472:SF26 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN CONTAINING 1 LEPOC|Ensembl=ENSLOCG00000012843.1|UniProtKB=W5N597 W5N597 PTHR46374:SF3 PROTEIN CBG07384 STAR-RELATED LIPID TRANSFER PROTEIN 5 molecular carrier activity#GO:0140104;sterol binding#GO:0032934;lipid carrier activity#GO:0005319;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;cholesterol binding#GO:0015485;transporter activity#GO:0005215;sterol transfer activity#GO:0120015;steroid binding#GO:0005496;alcohol binding#GO:0043178;cholesterol transfer activity#GO:0120020 lipid transport#GO:0006869;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;localization#GO:0051179;establishment of localization#GO:0051234;sterol transport#GO:0015918;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;transport#GO:0006810 LEPOC|Ensembl=ENSLOCG00000017978.1|UniProtKB=W5NN70 W5NN70 PTHR24366:SF127 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS SI:CH211-180F4.1 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000007750.1|UniProtKB=W5MM12 W5MM12 PTHR10730:SF6 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE 2 dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002327.1|UniProtKB=W5M2Y3 W5M2Y3 PTHR23316:SF8 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-7 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 nucleocytoplasmic transport#GO:0006913;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000794.1|UniProtKB=W5LXM4 W5LXM4 PTHR10489:SF618 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 5 protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine receptor activity#GO:0004896 positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;chemotaxis#GO:0006935;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000008890.1|UniProtKB=W5MR17 W5MR17 PTHR13304:SF0 GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN GPI-ANCHOR TRANSAMIDASE COMPONENT GPAA1 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;GPI anchored protein biosynthesis#GO:0180046;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endopeptidase complex#GO:1905369;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;peptidase complex#GO:1905368;cytoplasm#GO:0005737;caspase complex#GO:0008303;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000006155.1|UniProtKB=W5MGC7 W5MGC7 PTHR23267:SF486 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14_DELTA VARIABLE 4 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006367.1|UniProtKB=W5MH27 W5MH27 PTHR47224:SF1 TRANSMEMBRANE PROTEIN 25 TRANSMEMBRANE PROTEIN 25 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of system process#GO:0044057;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of signal transduction#GO:0009966;regulation of multicellular organismal process#GO:0051239;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000004900.1|UniProtKB=W5MBX9 W5MBX9 PTHR14097:SF7 OXIDOREDUCTASE HTATIP2 PROTEIN HTATIP2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012447.1|UniProtKB=W5N3W4 W5N3W4 PTHR11360:SF20 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 7 transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013343.1|UniProtKB=W5N737 W5N737 PTHR14432:SF2 PROSAPIP2 PROTEIN/5-AZACYTIDINE INDUCED GENE 2 TANK-BINDING KINASE 1-BINDING PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010425.1|UniProtKB=W5MWM0 W5MWM0 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 LEPOC|Ensembl=ENSLOCG00000011600.1|UniProtKB=W5N0U5 W5N0U5 PTHR10055:SF1 TRYPTOPHANYL-TRNA SYNTHETASE TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012954.1|UniProtKB=W5N5P1 W5N5P1 PTHR12582:SF7 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5C molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 LEPOC|Ensembl=ENSLOCG00000017540.1|UniProtKB=W5NLY6 W5NLY6 PTHR46291:SF9 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4C LEPOC|Ensembl=ENSLOCG00000001371.1|UniProtKB=W5LZK1 W5LZK1 PTHR12976:SF0 RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE DELTA-SUBUNIT RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT DELTA cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000001236.1|UniProtKB=W5LZ49 W5LZ49 PTHR22684:SF0 NULP1-RELATED RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000012148.1|UniProtKB=W5N2T3 W5N2T3 PTHR11593:SF10 60S RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN UL22 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000013900.1|UniProtKB=W5N931 W5N931 PTHR46899:SF4 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 27 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 27 enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;protein binding#GO:0005515 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000005427.1|UniProtKB=W5MDT9 W5MDT9 PTHR24178:SF2 MOLTING PROTEIN MLT-4 INVERSIN developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;intracellular protein localization#GO:0008104;system development#GO:0048731;animal organ development#GO:0048513;anatomical structure development#GO:0048856;localization#GO:0051179;multicellular organism development#GO:0007275;macromolecule localization#GO:0033036;kidney development#GO:0001822;renal system development#GO:0072001;protein localization to cilium#GO:0061512;multicellular organismal process#GO:0032501;protein localization to organelle#GO:0033365 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000012453.1|UniProtKB=W5N3X4 W5N3X4 PTHR15741:SF25 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MAX-LIKE PROTEIN X sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001680.1|UniProtKB=W5M0M2 W5M0M2 PTHR11188:SF183 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010498.1|UniProtKB=W5MWW1 W5MWW1 PTHR21236:SF6 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF5 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle organization#GO:0016050;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;regulation of cellular process#GO:0050794;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179 Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016006.1|UniProtKB=W5NGF1 W5NGF1 PTHR21315:SF2 APRATAXIN AND PNK-LIKE FACTOR-RELATED APRATAXIN AND PNK-LIKE FACTOR nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000016349.1|UniProtKB=W5NHT0 W5NHT0 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012308.1|UniProtKB=W5N3F9 W5N3F9 PTHR22754:SF33 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG C ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000013219.1|UniProtKB=W5N6M3 W5N6M3 PTHR21472:SF20 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000007868.1|UniProtKB=W5MMD7 W5MMD7 PTHR11442:SF88 HEMOGLOBIN FAMILY MEMBER SUPEROXIDE DISMUTASE heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488;tetrapyrrole binding#GO:0046906 transport#GO:0006810;developmental process#GO:0032502;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;multicellular organismal-level homeostasis#GO:0048871;cellular process#GO:0009987;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;localization#GO:0051179;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell development#GO:0048468;homeostatic process#GO:0042592 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219;globin#PC00107 LEPOC|Ensembl=ENSLOCG00000005726.1|UniProtKB=W5MF11 W5MF11 PTHR12546:SF62 FER-1-LIKE MYOFERLIN anatomical structure development#GO:0048856;plasma membrane organization#GO:0007009;wound healing#GO:0042060;animal gross anatomical part developmental process#GO:0160108;muscle structure development#GO:0061061;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;cellular component organization#GO:0016043;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;response to wounding#GO:0009611;response to stress#GO:0006950;membrane fusion#GO:0061025;cellular process#GO:0009987 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000001286.1|UniProtKB=W5LZ99 W5LZ99 PTHR13615:SF3 GLYCOSYLTRANSFERASE-LIKE 1 TRNA-QUEUOSINE ALPHA-MANNOSYLTRANSFERASE glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000013985.1|UniProtKB=W5N9C9 W5N9C9 PTHR23002:SF117 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN CCHC-TYPE ZINC FINGER NUCLEIC ACID BINDING PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of translation#GO:0045727;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014171.1|UniProtKB=W5N9Z8 W5N9Z8 PTHR24416:SF323 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR UFO transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714 cellular response to stimulus#GO:0051716;hemostasis#GO:0007599;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;transport#GO:0006810;negative regulation of cellular process#GO:0048523;blood coagulation#GO:0007596;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cell development#GO:0048468;endocytosis#GO:0006897;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;wound healing#GO:0042060;regulation of biological quality#GO:0065008;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;lymphocyte activation#GO:0046649;multicellular organism development#GO:0007275;leukocyte activation#GO:0045321;positive regulation of cell communication#GO:0010647;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;system development#GO:0048731;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;localization#GO:0051179;response to wounding#GO:0009611;regulation of signal transduction#GO:0009966;hemopoiesis#GO:0030097;cell migration#GO:0016477;negative regulation of apoptotic process#GO:0043066;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;phagocytosis#GO:0006909;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;platelet activation#GO:0030168;mononuclear cell differentiation#GO:1903131;leukocyte differentiation#GO:0002521;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;regulation of body fluid levels#GO:0050878;cell differentiation#GO:0030154;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;coagulation#GO:0050817;response to stress#GO:0006950;regulation of apoptotic process#GO:0042981;natural killer cell activation#GO:0030101;cell surface receptor signaling pathway#GO:0007166;import into cell#GO:0098657 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014589.1|UniProtKB=W5NBE7 W5NBE7 PTHR12125:SF12 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX PROTEIN 44 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007602.1|UniProtKB=W5MLG3 W5MLG3 PTHR24168:SF0 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 negative regulation of cell cycle#GO:0045786;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cell cycle process#GO:0010564;regulation of actin cytoskeleton organization#GO:0032956;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of mitotic cell cycle#GO:0045930;regulation of intracellular signal transduction#GO:1902531;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of gene expression#GO:0010468;regulation of actin filament-based process#GO:0032970;negative regulation of cell cycle process#GO:0010948;regulation of actin filament polymerization#GO:0030833;regulation of signal transduction#GO:0009966;regulation of actin polymerization or depolymerization#GO:0008064;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of actin filament organization#GO:0110053;regulation of mitotic cell cycle#GO:0007346;negative regulation of cytoskeleton organization#GO:0051494;regulation of DNA-templated transcription#GO:0006355;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;negative regulation of RNA metabolic process#GO:0051253;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of actin filament length#GO:0030832;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of actin filament polymerization#GO:0030837;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell population proliferation#GO:0042127;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of protein-containing complex assembly#GO:0031333;regulation of RNA metabolic process#GO:0051252;negative regulation of protein polymerization#GO:0032272;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell communication#GO:0010646;regulation of cell cycle phase transition#GO:1901987;negative regulation of organelle organization#GO:0010639 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000011134.1|UniProtKB=W5MZ67 W5MZ67 PTHR21393:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN MS27 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000014413.1|UniProtKB=W5NAT3 W5NAT3 PTHR12400:SF47 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;glycerophospholipid biosynthetic process#GO:0046474;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000000405.1|UniProtKB=W5LWD4 W5LWD4 PTHR24208:SF118 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000012525.1|UniProtKB=W5N472 W5N472 PTHR11814:SF282 SULFATE TRANSPORTER SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010008.1|UniProtKB=W5MV26 W5MV26 PTHR24338:SF8 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008034.1|UniProtKB=W5MMZ5 W5MMZ5 PTHR24229:SF91 NEUROPEPTIDES RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;peptide binding#GO:0042277;neuropeptide binding#GO:0042923 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001158.1|UniProtKB=W5LYU5 W5LYU5 PTHR31395:SF11 SHISA PROTEIN SHISA-LIKE-1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005670.1|UniProtKB=W5MEP1 W5MEP1 PTHR10278:SF0 CORTICOTROPIN-RELEASING FACTOR-BINDING PROTEIN CORTICOTROPIN-RELEASING HORMONE-BINDING PROTEIN peptide hormone binding#GO:0017046;binding#GO:0005488;hormone binding#GO:0042562 biological regulation#GO:0065007;regulation of system process#GO:0044057;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;negative regulation of multicellular organismal process#GO:0051241;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of multicellular organismal process#GO:0051239;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;regulation of localization#GO:0032879;regulation of transport#GO:0051049;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;negative regulation of cell communication#GO:0010648;regulation of hormone secretion#GO:0046883;hormone-mediated signaling pathway#GO:0009755;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002850.1|UniProtKB=W5M4P0 W5M4P0 PTHR45710:SF8 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN CONTAINING 5A-RELATED cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002359.1|UniProtKB=W5M308 W5M308 PTHR16127:SF12 TAXILIN ALPHA-TAXILIN membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004119.1|UniProtKB=W5M984 W5M984 PTHR24412:SF480 KELCH PROTEIN KELCH-LIKE PROTEIN 8 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006058.1|UniProtKB=W5MG05 W5MG05 PTHR14471:SF6 MARCH7/10 E3 UBIQUITIN PROTEIN LIGASE FAMILY MEMBER RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008085.1|UniProtKB=W5MN60 W5MN60 PTHR11071:SF594 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002746.1|UniProtKB=W5M4C6 W5M4C6 PTHR10730:SF9 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER INACTIVE GLYCOSYLTRANSFERASE 25 FAMILY MEMBER 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002731.1|UniProtKB=W5M4A5 W5M4A5 PTHR18884:SF6 SEPTIN SEPTIN-1 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cell cycle#GO:0007049;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cell cycle process#GO:0022402;cell division#GO:0051301;regulation of cellular process#GO:0050794;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;regulation of secretion#GO:0051046;localization#GO:0051179;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;macromolecule localization#GO:0033036;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of localization#GO:0032879;intracellular protein localization#GO:0008104 cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;presynapse#GO:0098793;secretory vesicle#GO:0099503;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic vesicle#GO:0008021;cell cortex#GO:0005938;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 LEPOC|Ensembl=ENSLOCG00000015923.1|UniProtKB=W5NG45 W5NG45 PTHR23227:SF87 BUCENTAUR RELATED PROTEIN CFDP2 LEPOC|Ensembl=ENSLOCG00000016325.1|UniProtKB=W5NHP3 W5NHP3 PTHR24329:SF520 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN UNC-42 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;cell development#GO:0048468;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006578.1|UniProtKB=W5MHT6 W5MHT6 PTHR45775:SF2 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN REM 1 anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;calcium channel regulator activity#GO:0005246;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000012272.1|UniProtKB=W5N393 W5N393 PTHR13462:SF6 CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL CALCIUM UNIPORTER REGULATORY SUBUNIT MCUB, MITOCHONDRIAL transporter regulator activity#GO:0141108;channel activity#GO:0015267;channel regulator activity#GO:0016247;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;active transmembrane transporter activity#GO:0022804;molecular function regulator activity#GO:0098772;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;molecular function inhibitor activity#GO:0140678;ion channel inhibitor activity#GO:0008200;calcium channel regulator activity#GO:0005246;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873 calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;mitochondrial calcium ion homeostasis#GO:0051560;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane protein complex#GO:0098796;organelle envelope#GO:0031967;calcium channel complex#GO:0034704;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703;transporter complex#GO:1990351;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000010764.1|UniProtKB=W5MXT3 W5MXT3 PTHR23103:SF7 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID-BETA PRECURSOR PROTEIN binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell development#GO:0048468 membrane microdomain#GO:0098857;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane raft#GO:0045121;intracellular vesicle#GO:0097708 protease inhibitor#PC00191 Blood coagulation#P00011>PN2#P00429;Alzheimer disease-amyloid secretase pathway#P00003>C83#P00100;Alzheimer disease-amyloid secretase pathway#P00003>APPalpha#P00097;Alzheimer disease-amyloid secretase pathway#P00003>APP#P00085;Alzheimer disease-amyloid secretase pathway#P00003>p3#P00086;Alzheimer disease-amyloid secretase pathway#P00003>C99#P00106;Alzheimer disease-presenilin pathway#P00004>APP#P00127;Alzheimer disease-presenilin pathway#P00004>C99#P00111;Alzheimer disease-presenilin pathway#P00004>APPbeta#P00151;Alzheimer disease-amyloid secretase pathway#P00003>AICD#P00080;Alzheimer disease-presenilin pathway#P00004>AICD#P00166;Alzheimer disease-presenilin pathway#P00004>Abeta#P00136;Alzheimer disease-amyloid secretase pathway#P00003>Abeta#P00096;Alzheimer disease-amyloid secretase pathway#P00003>APPbeta#P00104 LEPOC|Ensembl=ENSLOCG00000003082.1|UniProtKB=W5M5H7 W5M5H7 PTHR13989:SF16 REPLICATION PROTEIN A-RELATED REPLICATION FACTOR A PROTEIN 2 telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896 nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;replisome#GO:0030894;replication fork#GO:0005657;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;chromosome, telomeric region#GO:0000781 DNA replication#P00017>RPA#P00537 LEPOC|Ensembl=ENSLOCG00000011154.1|UniProtKB=W5MZA1 W5MZA1 PTHR12489:SF18 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 5 PROTEIN sensory perception of sound#GO:0007605;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to abiotic stimulus#GO:0009628;response to mechanical stimulus#GO:0009612;system process#GO:0003008;response to external stimulus#GO:0009605;detection of mechanical stimulus#GO:0050982;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014574.1|UniProtKB=W5NBC4 W5NBC4 PTHR43355:SF2 FLAVIN REDUCTASE (NADPH) FLAVIN REDUCTASE (NADPH) oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000015140.1|UniProtKB=W5NDC4 W5NDC4 PTHR11315:SF1 PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE FOLATE GAMMA-GLUTAMYL HYDROLASE peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000009935.1|UniProtKB=W5MUT8 W5MUT8 PTHR24078:SF568 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 1 protein binding#GO:0005515;binding#GO:0005488;transcription regulator activity#GO:0140110;Hsp70 protein binding#GO:0030544;transcription corepressor activity#GO:0003714;protein-folding chaperone binding#GO:0051087;transcription coregulator activity#GO:0003712;heat shock protein binding#GO:0031072 gene expression#GO:0010467;protein maturation#GO:0051604;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;metabolic process#GO:0008152;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;protein folding#GO:0006457;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001656.1|UniProtKB=W5M0S1 W5M0S1 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CELL ADHESION MOLECULE CEACAM5-RELATED cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000000638.1|UniProtKB=W5LX47 W5LX47 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006662.1|UniProtKB=W5MI37 W5MI37 SIGIRR PTHR11890:SF19 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER SINGLE IG IL-1-RELATED RECEPTOR cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015441.1|UniProtKB=W5NEE4 W5NEE4 PTHR13254:SF1 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 GOLGIN SUBFAMILY A MEMBER 7 localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;Golgi to plasma membrane transport#GO:0006893;protein targeting#GO:0006605;Golgi to plasma membrane protein transport#GO:0043001;protein targeting to membrane#GO:0006612;protein localization to cell periphery#GO:1990778;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000002022.1|UniProtKB=W5M1T6 W5M1T6 PTHR13586:SF2 SCD6 PROTEIN-RELATED PROTEIN LSM14 HOMOLOG A mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;P-body assembly#GO:0033962;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;cytoplasmic stress granule assembly#GO:0034063 cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009272.1|UniProtKB=W5MSG4 W5MSG4 PTHR16798:SF0 FANCONI ANEMIA GROUP C PROTEIN FANCC FANCONI ANEMIA GROUP C PROTEIN cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;cellular process#GO:0009987 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006533.1|UniProtKB=W5MHN5 W5MHN5 PTHR12358:SF26 SPHINGOSINE KINASE CERAMIDE KINASE-LIKE PROTEIN kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;lipid kinase activity#GO:0001727 negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000018031.1|UniProtKB=W5NNC3 W5NNC3 PTHR26451:SF881 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001040.1|UniProtKB=W5LYH6 W5LYH6 PTHR19134:SF433 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ALPHA hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000000163.1|UniProtKB=W5LVM7 W5LVM7 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013958.1|UniProtKB=W5N998 W5N998 PTHR21227:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;lyase activity#GO:0016829;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000003663.1|UniProtKB=W5M7L2 W5M7L2 PTHR19858:SF0 WD40 REPEAT PROTEIN PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000003294.1|UniProtKB=W5M678 W5M678 PTHR45620:SF13 PDF RECEPTOR-LIKE PROTEIN-RELATED SECRETIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015262.1|UniProtKB=W5NDS2 W5NDS2 PTHR12425:SF2 SYNEMBRYN CHAPERONE RIC-8B molecular function regulator activity#GO:0098772;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000008424.1|UniProtKB=W5MPH6 W5MPH6 PTHR23192:SF70 OLFACTOMEDIN-RELATED ADHESION G PROTEIN-COUPLED RECEPTOR L2 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006750.1|UniProtKB=W5MIF6 W5MIF6 PTHR10166:SF68 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VWFA AND CACHE DOMAIN-CONTAINING PROTEIN 1 monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;calcium channel complex#GO:0034704;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004977.1|UniProtKB=W5MC80 W5MC80 PTHR21496:SF19 FERREDOXIN-RELATED SI:CH211-212D10.2 binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008500.1|UniProtKB=W5MPN9 W5MPN9 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to external stimulus#GO:0009605;response to stimulus#GO:0050896 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015268.1|UniProtKB=W5NDS7 W5NDS7 PTHR31443:SF0 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 263 LEPOC|Ensembl=ENSLOCG00000002465.1|UniProtKB=W5M3E0 W5M3E0 PTHR10742:SF393 FLAVIN MONOAMINE OXIDASE PEROXISOMAL N(1)-ACETYL-SPERMINE_SPERMIDINE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 amine catabolic process#GO:0009310;metabolic process#GO:0008152;polyamine catabolic process#GO:0006598;polyamine metabolic process#GO:0006595;cellular process#GO:0009987;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000000659.1|UniProtKB=W5LXC7 W5LXC7 PTHR24092:SF57 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IF molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;intramembrane lipid carrier activity#GO:0140303 lipid transport#GO:0006869;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;macromolecule localization#GO:0033036;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876 endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;recycling endosome#GO:0055037;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010592.1|UniProtKB=W5MX63 W5MX63 PTHR19282:SF155 TETRASPANIN TETRASPANIN-2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011877.1|UniProtKB=W5N1X9 W5N1X9 PTHR45615:SF44 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-13 catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008;multicellular organismal process#GO:0032501 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000017958.1|UniProtKB=W5NN52 W5NN52 PTHR19297:SF81 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000000368.1|UniProtKB=W5LW95 W5LW95 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004771.1|UniProtKB=W5MBG4 W5MBG4 PTHR47266:SF40 ENDONUCLEASE-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009170.1|UniProtKB=W5MS37 W5MS37 PTHR23117:SF13 GUANYLATE KINASE-RELATED GUANYLATE KINASE phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside diphosphate metabolic process#GO:0009132;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine ribonucleoside diphosphate metabolic process#GO:0009179 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;transferase#PC00220 De novo purine biosynthesis#P02738>Guanylate kinase#P02904 LEPOC|Ensembl=ENSLOCG00000014686.1|UniProtKB=W5NBR7 W5NBR7 PTHR21236:SF1 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF6 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000017346.1|UniProtKB=W5NLE2 W5NLE2 PTHR10270:SF332 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-2 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;sensory organ development#GO:0007423;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;inner ear development#GO:0048839;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;ear development#GO:0043583;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;forebrain development#GO:0030900;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000010974.1|UniProtKB=W5MYK5 W5MYK5 PTHR45655:SF10 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;lyase activity#GO:0016829 signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;catalytic complex#GO:1902494 cyclase#PC00079;guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000005410.1|UniProtKB=W5MDR4 W5MDR4 PTHR11559:SF391 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000005928.1|UniProtKB=W5MFK0 W5MFK0 PTHR24031:SF594 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX52-RELATED primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000006803.1|UniProtKB=W5MIK9 W5MIK9 PTHR12429:SF8 NEURALIZED NEURALIZED-LIKE PROTEIN 2 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 LEPOC|Ensembl=ENSLOCG00000012046.1|UniProtKB=W5N2G3 W5N2G3 ATXN7L3 PTHR46367:SF1 ATAXIN-7-LIKE PROTEIN 3 ATAXIN-7-LIKE PROTEIN 3 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;SAGA complex#GO:0000124;DUBm complex#GO:0071819;nucleus#GO:0005634;chromatin#GO:0000785 LEPOC|Ensembl=ENSLOCG00000013579.1|UniProtKB=W5N7Y4 W5N7Y4 PTHR15594:SF1 PODOCALYXIN-LIKE PROTEIN 2 PODOCALYXIN-LIKE PROTEIN 2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000013935.1|UniProtKB=W5N976 W5N976 PTHR47130:SF6 SI:DKEY-19B23.11-RELATED ZONA PELLUCIDA PROTEIN AX 4 LEPOC|Ensembl=ENSLOCG00000015049.1|UniProtKB=W5ND15 W5ND15 PTHR46283:SF3 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 E3 UBIQUITIN-PROTEIN LIGASE MARCHF5 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 cellular process#GO:0009987;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of organelle organization#GO:0033043;regulation of mitochondrion organization#GO:0010821;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000018014.1|UniProtKB=W5NNA6 W5NNA6 PTHR11929:SF10 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE 9 fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;alpha-(1->3)-fucosyltransferase activity#GO:0046920;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000010672.1|UniProtKB=W5MXH1 W5MXH1 PTHR19865:SF0 U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2 U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2 U3 snoRNA binding#GO:0034511;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515 ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000007556.1|UniProtKB=W5MLB2 W5MLB2 PTHR13196:SF26 DENN DOMAIN-CONTAINING DENN DOMAIN CONTAINING 1B phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 intracellular transport#GO:0046907;transport#GO:0006810;localization within membrane#GO:0051668;cellular localization#GO:0051641;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456 cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006397.1|UniProtKB=W5MH83 W5MH83 PTHR23273:SF4 REPLICATION FACTOR A 1, RFA1 REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;binding#GO:0005488;nucleic acid binding#GO:0003676;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677 DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;organelle organization#GO:0006996;nucleotide-excision repair#GO:0006289;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;double-strand break repair via homologous recombination#GO:0000724;cellular component organization#GO:0016043;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA repair#GO:0006281;RNA-templated DNA biosynthetic process#GO:0006278;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;sexual reproduction#GO:0019953;recombinational repair#GO:0000725;telomere organization#GO:0032200;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;reproductive process#GO:0022414 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;replisome#GO:0030894;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002954.1|UniProtKB=W5M518 W5M518 PTHR46272:SF3 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G PROTEIN-COUPLED RECEPTOR 139-RELATED signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154 LEPOC|Ensembl=ENSLOCG00000017626.1|UniProtKB=W5NM72 W5NM72 PTHR24070:SF213 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000013099.1|UniProtKB=W5N680 W5N680 PTHR24123:SF49 ANKYRIN REPEAT-CONTAINING ANKYRIN-2 ISOFORM X1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011962.1|UniProtKB=W5N272 W5N272 PTHR13817:SF81 TITIN CONTACTIN-2 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000007114.1|UniProtKB=W5MJQ2 W5MJQ2 PTHR43599:SF13 MULTIFUNCTIONAL PROTEIN ADE2 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN-RELATED ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000014905.1|UniProtKB=W5NCJ6 W5NCJ6 PTHR12907:SF6 EGL NINE HOMOLOG-RELATED PROLYL HYDROXYLASE EGLN2 binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;dioxygenase activity#GO:0051213;cation binding#GO:0043169;ferrous iron binding#GO:0008198;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;biological regulation#GO:0065007;response to chemical#GO:0042221;regulation of apoptotic process#GO:0042981;response to hypoxia#GO:0001666;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to oxygen levels#GO:0070482;regulation of programmed cell death#GO:0043067;response to decreased oxygen levels#GO:0036293;cellular response to hypoxia#GO:0071456;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 LEPOC|Ensembl=ENSLOCG00000017306.1|UniProtKB=W5NLA2 W5NLA2 PTHR11437:SF67 RIBONUCLEASE RNASE 2-RELATED catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 blood vessel morphogenesis#GO:0048514;defense response to Gram-positive bacterium#GO:0050830;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;circulatory system development#GO:0072359;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to Gram-negative bacterium#GO:0050829;response to bacterium#GO:0009617;animal gross anatomical part developmental process#GO:0160108;defense response to bacterium#GO:0042742;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;multicellular organismal process#GO:0032501;response to other organism#GO:0051707;tube development#GO:0035295;developmental process#GO:0032502;multicellular organism development#GO:0007275;response to external stimulus#GO:0009605;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;defense response#GO:0006952 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001104.1|UniProtKB=W5LYQ8 W5LYQ8 PTHR11640:SF14 NEPHRIN KIN OF IRRE-LIKE PROTEIN 1 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000014418.1|UniProtKB=W5NAT8 W5NAT8 PTHR45690:SF19 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004782.1|UniProtKB=W5MBH6 W5MBH6 PTHR15427:SF2 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-3 protein complex involved in cell adhesion#GO:0098636;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;supramolecular fiber#GO:0099512 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007599.1|UniProtKB=W5MLG1 W5MLG1 PTHR24255:SF18 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1S SUBCOMPONENT serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000006630.1|UniProtKB=W5MI01 W5MI01 PTHR13002:SF1 C3ORF1 PROTEIN-RELATED COMPLEX I ASSEMBLY FACTOR TIMMDC1, MITOCHONDRIAL mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012034.1|UniProtKB=W5N2E7 W5N2E7 PTHR31102:SF1 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 9 MEMBER B2 LEPOC|Ensembl=ENSLOCG00000009806.1|UniProtKB=W5MUC8 W5MUC8 PTHR13800:SF50 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 2 transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;monoatomic cation transmembrane transporter activity#GO:0008324;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267 transport#GO:0006810;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011988.1|UniProtKB=W5N282 W5N282 PTHR12106:SF8 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS1 transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005731.1|UniProtKB=W5MEW1 W5MEW1 PTHR21580:SF57 SHIPPO-1-RELATED OUTER DENSE FIBER OF SPERM TAILS 3-LIKE 2B-RELATED cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;cellular process#GO:0009987;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatid development#GO:0007286;spermatid differentiation#GO:0048515;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006 microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000004881.1|UniProtKB=W5MBX7 W5MBX7 PTHR21394:SF0 MAU2 CHROMATID COHESION FACTOR HOMOLOG MAU2 CHROMATID COHESION FACTOR HOMOLOG catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 mitotic sister chromatid cohesion#GO:0007064;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;chromosome organization#GO:0051276;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000010949.1|UniProtKB=W5MYH4 W5MYH4 PTHR14845:SF5 COILED-COIL DOMAIN-CONTAINING 166 BASAL BODY-ORIENTATION FACTOR 1 LEPOC|Ensembl=ENSLOCG00000002646.1|UniProtKB=W5M402 W5M402 PTHR24168:SF23 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 3 regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament polymerization#GO:0030833;negative regulation of protein polymerization#GO:0032272;regulation of actin filament length#GO:0030832;negative regulation of protein-containing complex assembly#GO:0031333;regulation of biological quality#GO:0065008;negative regulation of cytoskeleton organization#GO:0051494;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of organelle organization#GO:0010639;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of cellular component organization#GO:0051129;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000007112.1|UniProtKB=W5MJQ1 W5MJQ1 PTHR46283:SF4 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 E3 UBIQUITIN-PROTEIN LIGASE MARCHF5 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of organelle organization#GO:0033043;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004795.1|UniProtKB=W5MBJ7 W5MBJ7 PTHR11346:SF80 GALECTIN GALECTIN-9B carbohydrate derivative binding#GO:0097367;binding#GO:0005488;carbohydrate binding#GO:0030246 regulation of mononuclear cell proliferation#GO:0032944;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;regulation of T cell activation#GO:0050863;negative regulation of cell-cell adhesion#GO:0022408;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;regulation of leukocyte proliferation#GO:0070663;negative regulation of T cell proliferation#GO:0042130;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of lymphocyte activation#GO:0051249;negative regulation of metabolic process#GO:0009892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of lymphocyte proliferation#GO:0050670;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of biosynthetic process#GO:0009889;negative regulation of cell activation#GO:0050866;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;negative regulation of multicellular organismal process#GO:0051241;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of T cell proliferation#GO:0042129;regulation of macromolecule metabolic process#GO:0060255;negative regulation of leukocyte cell-cell adhesion#GO:1903038;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000004993.1|UniProtKB=W5MCA6 W5MCA6 PTHR13024:SF2 MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN, LARGE SUBUNIT MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN-LIKE primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;lipoprotein metabolic process#GO:0042157 cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;basal part of cell#GO:0045178;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016693.1|UniProtKB=W5NJ14 W5NJ14 PTHR11537:SF274 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 metal ion transport#GO:0030001;striated muscle contraction#GO:0006941;actin-mediated cell contraction#GO:0070252;heart process#GO:0003015;muscle system process#GO:0003012;action potential#GO:0001508;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501;cardiac muscle cell action potential involved in contraction#GO:0086002;potassium ion transport#GO:0006813;blood circulation#GO:0008015;cellular process#GO:0009987;actin filament-based movement#GO:0030048;heart contraction#GO:0060047;system process#GO:0003008;cardiac muscle cell contraction#GO:0086003;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;muscle contraction#GO:0006936 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000002221.1|UniProtKB=W5M2J7 W5M2J7 PTHR15673:SF2 IQ CALMODULIN-BINDING MOTIF CONTAINING PROTEIN 1 IQ CALMODULIN-BINDING MOTIF-CONTAINING PROTEIN 1 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000009626.1|UniProtKB=W5MTQ7 W5MTQ7 PTHR46135:SF5 NME/NM23 FAMILY MEMBER 8 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 6 ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000003168.1|UniProtKB=W5M5T6 W5M5T6 PTHR43975:SF2 ZGC:101858 DEHYDROGENASES, SHORT CHAIN LEPOC|Ensembl=ENSLOCG00000014265.1|UniProtKB=W5NAA2 W5NAA2 PTHR10687:SF5 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 5 cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;recycling endosome membrane#GO:0055038;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;trans-Golgi network membrane#GO:0032588;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000008732.1|UniProtKB=W5MQH7 W5MQH7 PTHR43806:SF60 PEPTIDASE S8 PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 9 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000000073.1|UniProtKB=W5LVC9 W5LVC9 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010737.1|UniProtKB=W5MXQ3 W5MXQ3 RDX PTHR23281:SF14 MERLIN/MOESIN/EZRIN/RADIXIN RADIXIN binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of anatomical structure morphogenesis#GO:0022603;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880 intracellular organelle#GO:0043229;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000010856.1|UniProtKB=W5MY51 W5MY51 PTHR24347:SF18 SERINE/THREONINE-PROTEIN KINASE CAM KINASE-LIKE VESICLE-ASSOCIATED PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017916.1|UniProtKB=W5NN10 W5NN10 PTHR24241:SF182 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 19-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016057.1|UniProtKB=W5NGM3 W5NGM3 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009703.1|UniProtKB=W5MTY8 W5MTY8 PTHR12778:SF10 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED SOLUTE CARRIER FAMILY 33 MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009844.1|UniProtKB=W5MUH4 W5MUH4 PTHR16166:SF22 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13A molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013 catabolic process#GO:0009056;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;lipid localization#GO:0010876;macroautophagy#GO:0016236;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;lipid transport#GO:0006869;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;metabolic process#GO:0008152 mitochondrion#GO:0005739;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;endosome membrane#GO:0010008;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003813.1|UniProtKB=W5M841 W5M841 PTHR13105:SF22 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR 1 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004097.1|UniProtKB=W5M935 W5M935 PTHR11348:SF23 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102;binding#GO:0005488;integrin binding#GO:0005178;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;carbohydrate derivative binding#GO:0097367 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell adhesion#GO:0007155;biological regulation#GO:0065007;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010888.1|UniProtKB=W5MY90 W5MY90 PTHR13027:SF14 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG A molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 export from cell#GO:0140352;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;protein secretion#GO:0009306;transport#GO:0006810 cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;guanyl-nucleotide exchange factor complex#GO:0032045;intracellular protein-containing complex#GO:0140535;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 LEPOC|Ensembl=ENSLOCG00000000836.1|UniProtKB=W5LXS5 W5LXS5 PTHR23351:SF13 FOS TRANSCRIPTION FACTOR-RELATED BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000015161.1|UniProtKB=W5NDF2 W5NDF2 PTHR10598:SF0 SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000012579.1|UniProtKB=W5N4C6 W5N4C6 PTHR10129:SF15 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFG RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cell differentiation#GO:0045595;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of epithelial cell differentiation#GO:0030856;regulation of primary metabolic process#GO:0080090;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016144.1|UniProtKB=W5NGY3 W5NGY3 PTHR10689:SF11 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018029.1|UniProtKB=W5NNC1 W5NNC1 PTHR26451:SF989 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012088.1|UniProtKB=W5N2L2 W5N2L2 PTHR12122:SF5 RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cell projection membrane#GO:0031253;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;plasma membrane region#GO:0098590;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000005185.1|UniProtKB=W5MCY4 W5MCY4 PTHR24342:SF5 SERINE/THREONINE-PROTEIN KINASE 17 SERINE_THREONINE-PROTEIN KINASE 17B transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 signaling#GO:0023052;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012585.1|UniProtKB=W5N4E8 W5N4E8 PTHR13780:SF122 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-2 nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 regulation of metabolic process#GO:0019222;response to stress#GO:0006950;response to nutrient levels#GO:0031667;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular response to glucose starvation#GO:0042149;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of carbohydrate metabolic process#GO:0006109;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of carbohydrate biosynthetic process#GO:0043255;cellular response to stress#GO:0033554;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 LEPOC|Ensembl=ENSLOCG00000010186.1|UniProtKB=W5MVR2 W5MVR2 PTHR12131:SF7 ATP-DEPENDENT RNA AND DNA HELICASE EXOSOME RNA HELICASE MTR4 macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657 macromolecule catabolic process#GO:0009057;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;cellular component biogenesis#GO:0044085;nucleobase-containing compound catabolic process#GO:0034655;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;catabolic process#GO:0009056 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007531.1|UniProtKB=W5ML74 W5ML74 PTHR24049:SF1 CRUMBS FAMILY MEMBER PROTEIN CRUMBS HOMOLOG 1 establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000007990.1|UniProtKB=W5MMU2 W5MMU2 PTHR13367:SF28 UBIQUITIN THIOESTERASE UBIQUITIN THIOESTERASE ZRANB1 deubiquitinase activity#GO:0101005;modification-dependent protein binding#GO:0140030;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;catalytic activity#GO:0003824;polyubiquitin modification-dependent protein binding#GO:0031593;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of Wnt signaling pathway#GO:0030177;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;post-translational protein modification#GO:0043687;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein modification process#GO:0036211;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;modification-dependent protein catabolic process#GO:0019941;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000010875.1|UniProtKB=W5MY78 W5MY78 PTHR44117:SF2 INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 intracellular transport#GO:0046907;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;developmental process#GO:0032502;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;neurogenesis#GO:0022008;inner ear development#GO:0048839;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;anatomical structure development#GO:0048856;non-motile cilium assembly#GO:1905515;localization#GO:0051179;system development#GO:0048731;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;renal system development#GO:0072001;kidney development#GO:0001822;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;generation of neurons#GO:0048699;cellular localization#GO:0051641;neuron development#GO:0048666;cilium organization#GO:0044782;ear development#GO:0043583;cilium assembly#GO:0060271;cellular component organization#GO:0016043;inner ear receptor cell stereocilium organization#GO:0060122;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468 ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;cilium#GO:0005929;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012200.1|UniProtKB=W5N306 W5N306 PTHR12591:SF3 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE CATALYTIC SUBUNIT 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791 primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;small molecule metabolic process#GO:0044281;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;glucose metabolic process#GO:0006006 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 phosphatase#PC00181;hydrolase#PC00121 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 LEPOC|Ensembl=ENSLOCG00000010237.1|UniProtKB=W5MVX8 W5MVX8 PTHR11831:SF1 30S 40S RIBOSOMAL PROTEIN U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3 structural molecule activity#GO:0005198;RNA binding#GO:0003723;snoRNA binding#GO:0030515;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000929.1|UniProtKB=W5LY32 W5LY32 PTHR10489:SF686 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 5-LIKE-RELATED signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 signal transduction#GO:0007165;immune response#GO:0006955;cellular process#GO:0009987;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;response to external stimulus#GO:0009605;calcium-mediated signaling#GO:0019722;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;locomotion#GO:0040011;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell chemotaxis#GO:0060326;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005196.1|UniProtKB=W5MCZ6 W5MCZ6 PTHR21040:SF5 BCDNA.GH04120 BETA-N-ACETYLHEXOSAMINIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 LEPOC|Ensembl=ENSLOCG00000014305.1|UniProtKB=W5NAG8 W5NAG8 PTHR11255:SF33 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE KAPPA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000014094.1|UniProtKB=W5N9Q6 W5N9Q6 PTHR12673:SF14 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 3 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;filopodium assembly#GO:0046847;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000015509.1|UniProtKB=W5NEN0 W5NEN0 PTHR17597:SF0 MEMBRANE PROTEIN MLC1 MEMBRANE PROTEIN MLC1 biological regulation#GO:0065007;regulation of response to stress#GO:0080134;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000014212.1|UniProtKB=W5NA48 W5NA48 PTHR13768:SF23 SOLUBLE NSF ATTACHMENT PROTEIN SNAP ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein transport#GO:0015031;cellular component disassembly#GO:0022411;cellular localization#GO:0051641;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;synaptic transmission, glutamatergic#GO:0035249;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;synaptic signaling#GO:0099536;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;protein-containing complex disassembly#GO:0032984;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;chemical synaptic transmission#GO:0007268;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;macromolecule localization#GO:0033036 axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cell projection#GO:0042995;neuron projection terminus#GO:0044306;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;SNARE complex#GO:0031201;synapse#GO:0045202;cellular anatomical structure#GO:0110165;axon terminus#GO:0043679;cell junction#GO:0030054;neuron projection#GO:0043005;presynapse#GO:0098793;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006424.1|UniProtKB=W5MHA5 W5MHA5 PTHR11689:SF169 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)_CL(-) EXCHANGE TRANSPORTER 7 monoatomic anion channel activity#GO:0005253;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;active transmembrane transporter activity#GO:0022804 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;late endosome#GO:0005770;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;monoatomic ion channel complex#GO:0034702;lysosomal membrane#GO:0005765;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000017457.1|UniProtKB=W5NLQ3 W5NLQ3 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010133.1|UniProtKB=W5MVL4 W5MVL4 PTHR23119:SF57 DISCS LARGE PROTEIN SCRIBBLE HOMOLOG molecular adaptor activity#GO:0060090;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 endocytic recycling#GO:0032456;protein localization to membrane#GO:0072657;regulation of biological quality#GO:0065008;protein transport#GO:0015031;cellular localization#GO:0051641;cell adhesion#GO:0007155;receptor clustering#GO:0043113;establishment or maintenance of cell polarity#GO:0007163;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;cell-cell adhesion#GO:0098609;endosomal transport#GO:0016197;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;protein localization to synapse#GO:0035418;intracellular protein transport#GO:0006886;protein localization to cell periphery#GO:1990778;cell motility#GO:0048870;protein localization to plasma membrane#GO:0072659;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;establishment or maintenance of bipolar cell polarity#GO:0061245;protein localization to cell junction#GO:1902414;establishment or maintenance of apical/basal cell polarity#GO:0035088;biological regulation#GO:0065007;cell migration#GO:0016477;endosome to plasma membrane protein transport#GO:0099638;macromolecule localization#GO:0033036;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907 adherens junction#GO:0005912;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;basal part of cell#GO:0045178;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006691.1|UniProtKB=W5MI69 W5MI69 PTHR21029:SF5 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G-PROTEIN SIGNALING 9-BINDING PROTEIN regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000009769.1|UniProtKB=W5MU85 W5MU85 PTHR12784:SF3 STEERIN NEURON NAVIGATOR 1 developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;neuron migration#GO:0001764;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;neurogenesis#GO:0022008;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell migration#GO:0016477;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;microtubule bundle formation#GO:0001578;generation of neurons#GO:0048699;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component organization#GO:0016043;cell motility#GO:0048870;cell differentiation#GO:0030154 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;axon#GO:0030424;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;main axon#GO:0044304 LEPOC|Ensembl=ENSLOCG00000003820.1|UniProtKB=W5M848 W5M848 PTHR11486:SF23 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 5 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;fibroblast growth factor receptor binding#GO:0005104;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000012834.1|UniProtKB=W5N585 W5N585 PTHR46543:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule catabolic process#GO:0009057;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA metabolic process#GO:0016073;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000006703.1|UniProtKB=W5MI86 W5MI86 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004971.1|UniProtKB=W5MC89 W5MC89 PTHR24042:SF2 NEL HOMOLOG PROTEIN KINASE C-BINDING PROTEIN NELL1 glycosaminoglycan binding#GO:0005539;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201 regulation of cell differentiation#GO:0045595;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000014169.1|UniProtKB=W5N9Z6 W5N9Z6 PTHR12092:SF2 PLECKSTRIN PLECKSTRIN-2 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010994.1|UniProtKB=W5MYM7 W5MYM7 PTHR10605:SF30 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;deacylase activity#GO:0160215;deacetylase activity#GO:0019213;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001136.1|UniProtKB=W5LYT0 W5LYT0 PTHR12758:SF25 APOPTOSIS INHIBITOR 5-RELATED APOPTOSIS INHIBITOR 5 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000750.1|UniProtKB=W5LXI8 W5LXI8 PTHR11785:SF519 AMINO ACID TRANSPORTER LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 1-LIKE amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;transport#GO:0006810;amino acid transport#GO:0006865 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005781.1|UniProtKB=W5MF25 W5MF25 PTHR10183:SF30 CALPAIN CALPAIN-10 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000003967.1|UniProtKB=W5M8N2 W5M8N2 PTHR12371:SF10 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 LEPOC|Ensembl=ENSLOCG00000001252.1|UniProtKB=W5LZ62 W5LZ62 PTHR48176:SF4 DDRGK DOMAIN-CONTAINING PROTEIN 1 DDRGK DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;protein binding#GO:0005515 regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;connective tissue development#GO:0061448;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;tissue development#GO:0009888;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;negative regulation of signaling#GO:0023057;cartilage development#GO:0051216;negative regulation of cell communication#GO:0010648;regulation of cellular response to stress#GO:0080135;system development#GO:0048731;anatomical structure development#GO:0048856;negative regulation of intracellular signal transduction#GO:1902532;skeletal system development#GO:0001501;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000010854.1|UniProtKB=W5MY56 W5MY56 PTHR17271:SF12 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN MYOSIN PHOSPHATASE RHO-INTERACTING PROTEIN ISOFORM X1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000008551.1|UniProtKB=W5MPU2 W5MPU2 PTHR19849:SF1 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN F-BOX_WD REPEAT-CONTAINING PROTEIN 7 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macroautophagy#GO:0016236;proteasomal protein catabolic process#GO:0010498;autophagy#GO:0006914;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Notch signaling pathway#P00045>Sel 10#P01102;Parkinson disease#P00049>hSel10#P01240 LEPOC|Ensembl=ENSLOCG00000014633.1|UniProtKB=W5NBL4 W5NBL4 PTHR10183:SF393 CALPAIN CALPAIN-12 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;proteolysis#GO:0006508;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;primary metabolic process#GO:0044238;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000018059.1|UniProtKB=W5NNF1 W5NNF1 PTHR24241:SF17 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V1A RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;circulatory system process#GO:0003013;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;response to chemical#GO:0042221;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;response to hormone#GO:0009725;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013561.1|UniProtKB=W5N7W6 W5N7W6 PTHR10404:SF33 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE TRANSFERRIN RECEPTOR PROTEIN 2 catalytic activity#GO:0003824;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000015525.1|UniProtKB=W5NEP9 W5NEP9 PTHR35087:SF1 SIMILAR TO HYPOTHETICAL PROTEIN FLJ40298 CILIARY MICROTUBULE INNER PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000012609.1|UniProtKB=W5N4F7 W5N4F7 PTHR11256:SF11 BCL-2 RELATED APOPTOSIS REGULATOR BCL-2 channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;signaling#GO:0023052;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;organelle organization#GO:0006996;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of cellular process#GO:0050794;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of cellular process#GO:0048522;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968 Apoptosis signaling pathway#P00006>Bcl-2#P00270;Oxidative stress response#P00046>Bcl-2#P01123;CCKR signaling map#P06959>BCL2#P07059 LEPOC|Ensembl=ENSLOCG00000006270.1|UniProtKB=W5MGS0 W5MGS0 PTHR18929:SF265 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;response to stimulus#GO:0050896;protein folding#GO:0006457;biosynthetic process#GO:0009058;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013734.1|UniProtKB=W5N8I4 W5N8I4 PTHR23122:SF37 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK 55 KDA ERYTHROCYTE MEMBRANE PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 macromolecule localization#GO:0033036;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of transport#GO:0051049;intracellular protein localization#GO:0008104;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of neurotransmitter secretion#GO:0046928;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;regulation of secretion by cell#GO:1903530;localization#GO:0051179;regulation of secretion#GO:0051046 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010706.1|UniProtKB=W5MXL0 W5MXL0 PTHR18945:SF335 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-6 channel activity#GO:0015267;molecular transducer activity#GO:0060089;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276;signaling receptor activity#GO:0038023;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;neurotransmitter receptor activity#GO:0030594;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;anatomical structure development#GO:0048856;chloride transmembrane transport#GO:1902476;localization#GO:0051179;cell communication#GO:0007154;cellular process#GO:0009987;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;chloride transport#GO:0006821;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;signaling#GO:0023052;synapse assembly#GO:0007416;animal gross anatomical part developmental process#GO:0160108;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085 signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589;cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;dendrite#GO:0030425;cell projection membrane#GO:0031253;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000012164.1|UniProtKB=W5N2V5 W5N2V5 PTHR46426:SF1 PROTEIN DISULFIDE-ISOMERASE TMX3 PROTEIN DISULFIDE-ISOMERASE TMX3 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cell surface#GO:0009986;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004877.1|UniProtKB=W5MBV7 W5MBV7 PTHR11849:SF312 ETS ETS VARIANT TRANSCRIPTION FACTOR 2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000014828.1|UniProtKB=W5NC99 W5NC99 PTHR45668:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 5 phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000002070.1|UniProtKB=W5M1Z5 W5M1Z5 PTHR11037:SF18 TRANSCRIPTION FACTOR CP2 TRANSCRIPTION FACTOR CP2-LIKE PROTEIN 1 transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004630.1|UniProtKB=W5MAY6 W5MAY6 PTHR37679:SF1 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000015903.1|UniProtKB=W5NG24 W5NG24 PTHR12834:SF12 SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;cellular localization#GO:0051641;establishment of localization#GO:0051234;protein targeting to ER#GO:0045047;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599 ribonucleoprotein complex#GO:1990904;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014283.1|UniProtKB=W5NAC5 W5NAC5 PTHR46114:SF2 APPLE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED LEPOC|Ensembl=ENSLOCG00000005083.1|UniProtKB=W5MCL3 W5MCL3 PTHR10985:SF15 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000005550.1|UniProtKB=W5MEB0 W5MEB0 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515 protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 LEPOC|Ensembl=ENSLOCG00000017399.1|UniProtKB=W5NLJ5 W5NLJ5 PTHR26451:SF1002 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTOR 148-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001046.1|UniProtKB=W5LYG5 W5LYG5 PTHR16120:SF0 AP-5 COMPLEX SUBUNIT SIGMA-1 AP-5 COMPLEX SUBUNIT SIGMA-1 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;AP-type membrane coat adaptor complex#GO:0030119;lytic vacuole#GO:0000323;lysosome#GO:0005764;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475 LEPOC|Ensembl=ENSLOCG00000007174.1|UniProtKB=W5MJX2 W5MJX2 PTHR11675:SF18 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 12 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000010669.1|UniProtKB=W5MXF8 W5MXF8 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002207.1|UniProtKB=W5M2H2 W5M2H2 PTHR18949:SF1 CALDESMON LYMPHOCYTE-SPECIFIC PROTEIN 1 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000013493.1|UniProtKB=W5N7M7 W5N7M7 PTHR12806:SF0 EAP30 SUBUNIT OF ELL COMPLEX VACUOLAR-SORTING PROTEIN SNF8 catabolic process#GO:0009056;protein localization to organelle#GO:0033365;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization to vacuole#GO:0072666;protein transport#GO:0015031;cellular localization#GO:0051641;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endosomal transport#GO:0016197;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000010796.1|UniProtKB=W5MXX1 W5MXX1 PTHR45656:SF4 PROTEIN CBR-CLEC-78 COMPLEMENT COMPONENT RECEPTOR 1-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000005361.1|UniProtKB=W5MDP0 W5MDP0 PTHR12027:SF89 WNT RELATED PROTEIN WNT-10A cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system development#GO:0048731;cell fate commitment#GO:0045165;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 LEPOC|Ensembl=ENSLOCG00000014521.1|UniProtKB=W5NB70 W5NB70 PTHR24416:SF66 TYROSINE-PROTEIN KINASE RECEPTOR NT-3 GROWTH FACTOR RECEPTOR protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein kinase activity#GO:0004672 response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular response to nerve growth factor stimulus#GO:1990090;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;axon#GO:0030424 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005261.1|UniProtKB=W5MD78 W5MD78 PTHR24390:SF94 ZINC FINGER PROTEIN TRANSCRIPTION FACTOR E4F1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013300.1|UniProtKB=W5N6Y3 W5N6Y3 PTHR24198:SF176 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND SOCS BOX PROTEIN 14 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000010199.1|UniProtKB=W5MVT5 W5MVT5 PTHR12178:SF11 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 1 regulation of biosynthetic process#GO:0009889;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006687.1|UniProtKB=W5MI66 W5MI66 PTHR47980:SF42 LD44762P RAS-RELATED PROTEIN RAB-13 localization within membrane#GO:0051668;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;secretion by cell#GO:0032940;endocytic recycling#GO:0032456;export from cell#GO:0140352;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;trans-Golgi network transport vesicle#GO:0030140;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;Golgi-associated vesicle#GO:0005798;clathrin-coated vesicle#GO:0030136 LEPOC|Ensembl=ENSLOCG00000005722.1|UniProtKB=W5MEU6 W5MEU6 PTHR45964:SF8 WSCD FAMILY MEMBER CG9164 SIALATE:O-SULFOTRANSFERASE 1 LEPOC|Ensembl=ENSLOCG00000004287.1|UniProtKB=W5M9R5 W5M9R5 PTHR14215:SF3 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 1-LIKE cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000009668.1|UniProtKB=W5MTW1 W5MTW1 PTHR13285:SF19 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE HHAT-LIKE PROTEIN acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000002017.1|UniProtKB=W5M1T8 W5M1T8 PTHR24231:SF14 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR SUCCINATE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003653.1|UniProtKB=W5M7I4 W5M7I4 PTHR12751:SF4 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 4 protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 tissue development#GO:0009888;cell migration#GO:0016477;neural crest cell development#GO:0014032;cytoskeleton organization#GO:0007010;stem cell differentiation#GO:0048863;organelle organization#GO:0006996;cellular process#GO:0009987;neural crest cell migration#GO:0001755;cellular developmental process#GO:0048869;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;mesenchyme development#GO:0060485;mesenchymal cell differentiation#GO:0048762;neural crest cell differentiation#GO:0014033;developmental process#GO:0032502;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;stem cell development#GO:0048864;actin filament-based process#GO:0030029 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000001681.1|UniProtKB=W5M0M3 W5M0M3 PTHR11304:SF75 EPHRIN EPHRIN-A2 ISOFORM X1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 system development#GO:0048731;osteoclast differentiation#GO:0030316;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;hemopoiesis#GO:0030097;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;leukocyte differentiation#GO:0002521;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016124.1|UniProtKB=W5NGV7 W5NGV7 PTHR13362:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S33 SMALL RIBOSOMAL SUBUNIT PROTEIN MS33 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012466.1|UniProtKB=W5N400 W5N400 PTHR23255:SF50 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1A signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transforming growth factor beta receptor activity#GO:0005024;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674 cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;pattern specification process#GO:0007389;signaling#GO:0023052;cell differentiation#GO:0030154;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;dorsal/ventral pattern formation#GO:0009953;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;response to endogenous stimulus#GO:0009719;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;regionalization#GO:0003002;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 serine/threonine protein kinase receptor#PC00205 Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442 LEPOC|Ensembl=ENSLOCG00000000529.1|UniProtKB=W5LWW1 W5LWW1 PTHR11505:SF205 L1 TRANSPOSABLE ELEMENT-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000004056.1|UniProtKB=W5M8Y3 W5M8Y3 GATC PTHR15004:SF0 GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004834.1|UniProtKB=W5MBP8 W5MBP8 PTHR13580:SF6 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE_SERINE-RICH NUCLEAR PROTEIN 2 DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000016545.1|UniProtKB=W5NIH3 W5NIH3 PTHR24366:SF65 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEATS AND IMMUNOGLOBULIN LIKE DOMAINS 3 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000004220.1|UniProtKB=W5M9I7 W5M9I7 PTHR19964:SF33 MULTIPLE PDZ DOMAIN PROTEIN LIGAND OF NUMB PROTEIN X 2 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 scaffold/adaptor protein#PC00226 Notch signaling pathway#P00045>LNXp80#P01111 LEPOC|Ensembl=ENSLOCG00000016830.1|UniProtKB=W5NJJ2 W5NJJ2 PTHR24034:SF200 EGF-LIKE DOMAIN-CONTAINING PROTEIN FI18763P1-RELATED extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000011793.1|UniProtKB=W5N1K0 W5N1K0 PTHR12290:SF10 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 1 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;vesicle#GO:0031982;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014209.1|UniProtKB=W5NA42 W5NA42 PTHR16089:SF23 REST COREPRESSOR COREST PROTEIN-RELATED ZINC FINGER PROTEIN 541 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000013366.1|UniProtKB=W5N783 W5N783 PTHR19325:SF583 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 defense/immunity protein#PC00090;complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000012895.1|UniProtKB=W5N5G9 W5N5G9 PTHR22957:SF204 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 1 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000004626.1|UniProtKB=W5MAY7 W5MAY7 PTHR23055:SF195 CALCIUM BINDING PROTEINS PHD FINGER PROTEIN 24 ISOFORM X1 calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;molecular function activator activity#GO:0140677;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;cyclase regulator activity#GO:0010851;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000001064.1|UniProtKB=W5LYJ1 W5LYJ1 PTHR46187:SF3 ALKALINE CERAMIDASE 3 ALKALINE CERAMIDASE 3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingoid biosynthetic process#GO:0046520 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000017671.1|UniProtKB=W5NMB7 W5NMB7 PTHR32341:SF21 INTERFERON-INDUCIBLE GTPASE IRG-TYPE G DOMAIN-CONTAINING PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000000946.1|UniProtKB=W5LY45 W5LY45 PTHR24246:SF57 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010386.1|UniProtKB=W5MWH3 W5MWH3 PTHR45919:SF1 GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004429.1|UniProtKB=W5MA84 W5MA84 PTHR13393:SF0 SAM-DEPENDENT METHYLTRANSFERASE RNA N(6)-ADENOSINE-METHYLTRANSFERASE METTL16 RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;post-transcriptional regulation of gene expression#GO:0010608;RNA splicing#GO:0008380 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004888.1|UniProtKB=W5MBX8 W5MBX8 PTHR10782:SF7 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 1 molecular function inhibitor activity#GO:0140678;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;transcription regulator activity#GO:0140110;SUMO transferase activity#GO:0019789;SUMO ligase activity#GO:0061665;acyltransferase activity#GO:0016746;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;transcription coactivator activity#GO:0003713;catalytic activity, acting on a protein#GO:0140096;transcription coregulator activity#GO:0003712;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of transcription by RNA polymerase II#GO:0006357;metabolic process#GO:0008152;protein sumoylation#GO:0016925;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of RNA metabolic process#GO:0051252;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;post-translational protein modification#GO:0043687 membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014813.1|UniProtKB=W5NC83 W5NC83 PTHR12879:SF22 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID 4-DESATURASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 hydroxylase#PC00122;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005775.1|UniProtKB=W5MF15 W5MF15 PTHR21500:SF0 TUBULIN-SPECIFIC CHAPERONE A TUBULIN-SPECIFIC CHAPERONE A binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000003890.1|UniProtKB=W5M8D3 W5M8D3 PTHR17117:SF3 NADH-UBIQUINONE OXIDOREDUCTASE NADH:UBIQUINONE OXIDOREDUCTASE SUBUNIT V3 cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000000519.1|UniProtKB=W5LWR6 W5LWR6 PTHR22055:SF0 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004110.1|UniProtKB=W5M954 W5M954 PTHR43134:SF7 SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA CELL DIVISION PROTEIN FTSY HOMOLOG, CHLOROPLASTIC pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;hydrolase activity#GO:0016787;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 localization#GO:0051179;establishment of localization#GO:0051234;protein targeting#GO:0006605;establishment of protein localization#GO:0045184 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein#PC00020;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017911.1|UniProtKB=W5NN05 W5NN05 PTHR24365:SF539 TOLL-LIKE RECEPTOR TIR DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;immune system process#GO:0002376;regulation of response to external stimulus#GO:0032101;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of response to biotic stimulus#GO:0002831;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003360.1|UniProtKB=W5M6G3 W5M6G3 VSIG10 PTHR12231:SF222 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10 protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011207.1|UniProtKB=W5MZG3 W5MZG3 PTHR46805:SF2 FORKHEAD BOX PROTEIN J1 FORKHEAD BOX PROTEIN J1-A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000007336.1|UniProtKB=W5MKH6 W5MKH6 PTHR22611:SF2 PROTEIN NAKED CUTICLE PROTEIN NAKED CUTICLE HOMOLOG 1 negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of Wnt signaling pathway#GO:0030178;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Wnt signaling pathway#P00057>Naked#P01427 LEPOC|Ensembl=ENSLOCG00000011182.1|UniProtKB=W5MZC8 W5MZC8 PTHR22937:SF233 E3 UBIQUITIN-PROTEIN LIGASE RNF165 E3 UBIQUITIN-PROTEIN LIGASE ARK2C acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;primary metabolic process#GO:0044238;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of BMP signaling pathway#GO:0030510;axon guidance#GO:0007411;axon development#GO:0061564;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;positive regulation of signaling#GO:0023056;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of BMP signaling pathway#GO:0030513;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;proteasomal protein catabolic process#GO:0010498 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015888.1|UniProtKB=W5NG10 W5NG10 PTHR11133:SF28 SACCHAROPINE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000015079.1|UniProtKB=W5ND51 W5ND51 PTHR12420:SF15 PHD FINGER PROTEIN PHD FINGER PROTEIN 6 enzyme binding#GO:0019899;histone binding#GO:0042393;binding#GO:0005488;histone deacetylase binding#GO:0042826;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001135.1|UniProtKB=W5LYS8 W5LYS8 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000001545.1|UniProtKB=W5M066 W5M066 PTHR43671:SF111 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK11 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cellular response to stress#GO:0033554;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of cell cycle#GO:0045786;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;DNA integrity checkpoint signaling#GO:0031570 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000014631.1|UniProtKB=W5NBK0 W5NBK0 PTHR12876:SF27 N4BP1-RELATED RIBONUCLEASE ZC3H12B-RELATED RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000012276.1|UniProtKB=W5N3A2 W5N3A2 PTHR10373:SF11 TRANSCRIPTION FACTOR 7 FAMILY MEMBER LYMPHOID ENHANCER-BINDING FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell surface receptor signaling pathway#GO:0007166 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;RNA polymerase II transcription regulator complex#GO:0090575;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Cadherin signaling pathway#P00012>TCF/LEF#P00465;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Wnt signaling pathway#P00057>TCF#P01437 LEPOC|Ensembl=ENSLOCG00000002557.1|UniProtKB=W5M3P0 W5M3P0 PTHR11829:SF388 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN CROCODILE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000005734.1|UniProtKB=W5MEW7 W5MEW7 PTHR21713:SF38 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NAC ALPHA DOMAIN CONTAINING cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000013430.1|UniProtKB=W5N7E9 W5N7E9 PTHR11304:SF34 EPHRIN EPHRIN-B3 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon development#GO:0061564;axon guidance#GO:0007411;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 membrane-bound signaling molecule#PC00152;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007812.1|UniProtKB=W5MM75 W5MM75 PTHR11711:SF422 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 3 carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 LEPOC|Ensembl=ENSLOCG00000002502.1|UniProtKB=W5M3I3 W5M3I3 PTHR11348:SF33 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CELLULAR COMMUNICATION NETWORK FACTOR 1, LIKE 1 PRECURSOR-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;glycosaminoglycan binding#GO:0005539;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178 positive regulation of cell motility#GO:2000147;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of developmental process#GO:0050793;cell adhesion#GO:0007155;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cellular process#GO:0009987;positive regulation of cell migration#GO:0030335;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;positive regulation of locomotion#GO:0040017 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000000684.1|UniProtKB=W5LXA0 W5LXA0 PTHR24070:SF385 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE HRAS catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 Ras Pathway#P04393>Ras#P04547;EGF receptor signaling pathway#P00018>Ras#P00552;TGF-beta signaling pathway#P00052>Ras-GDP#P01291;PDGF signaling pathway#P00047>Ras#P01154;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;Integrin signalling pathway#P00034>Ras#P00916;Angiogenesis#P00005>Ras#P00238;B cell activation#P00010>Ras#P00376;PI3 kinase pathway#P00048>Ras#P01182;T cell activation#P00053>Ras#P01306;FGF signaling pathway#P00021>Ras#P00633;p53 pathway feedback loops 2#P04398>Ras#P04651 LEPOC|Ensembl=ENSLOCG00000003219.1|UniProtKB=W5M5Z5 W5M5Z5 PTHR34755:SF1 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED SERINE_ARGININE REPETITIVE MATRIX PROTEIN 4 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 multicellular organismal process#GO:0032501;developmental maturation#GO:0021700;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cell maturation#GO:0048469;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;anatomical structure maturation#GO:0071695;anatomical structure development#GO:0048856;system development#GO:0048731;gene expression#GO:0010467;nervous system development#GO:0007399;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;multicellular organism development#GO:0007275;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;cell development#GO:0048468;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;nucleic acid biosynthetic process#GO:0141187;generation of neurons#GO:0048699 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010848.1|UniProtKB=W5MY38 W5MY38 PTHR15909:SF0 39S RIBOSOMAL PROTEIN L35, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000001808.1|UniProtKB=W5M144 W5M144 MED16 PTHR13224:SF6 THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 16 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592 LEPOC|Ensembl=ENSLOCG00000014189.1|UniProtKB=W5NA25 W5NA25 PTHR43782:SF4 ARGINASE ARGINASE-2, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 amino acid metabolic process#GO:0006520;regulation of multicellular organismal process#GO:0051239;arginine metabolic process#GO:0006525;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;small molecule metabolic process#GO:0044281;negative regulation of metabolic process#GO:0009892;carboxylic acid metabolic process#GO:0019752;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003572.1|UniProtKB=W5M770 W5M770 PTHR14948:SF46 NG5 DISPANIN SUBFAMILY A MEMBER 2B-RELATED cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004179.1|UniProtKB=W5M9H7 W5M9H7 PTHR24416:SF535 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN RECEPTOR transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 positive regulation of cellular process#GO:0048522;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;response to peptide hormone#GO:0043434;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;positive regulation of signal transduction#GO:0009967;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;homeostatic process#GO:0042592;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;chemical homeostasis#GO:0048878;regulation of MAPK cascade#GO:0043408;glucose homeostasis#GO:0042593;response to endogenous stimulus#GO:0009719;carbohydrate homeostasis#GO:0033500;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;positive regulation of signaling#GO:0023056 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;axon#GO:0030424;transferase complex, transferring phosphorus-containing groups#GO:0061695;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;transferase complex#GO:1990234;protein kinase complex#GO:1902911 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>IR#P06802;PI3 kinase pathway#P00048>IR#P01187;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895 LEPOC|Ensembl=ENSLOCG00000011523.1|UniProtKB=W5N0K3 W5N0K3 PTHR24241:SF132 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;response to endogenous stimulus#GO:0009719;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010158.1|UniProtKB=W5MVN0 W5MVN0 PTHR10379:SF5 MTG8 ETO EIGHT TWENTY ONE PROTEIN PROTEIN CBFA2T1 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007393.1|UniProtKB=W5MKR2 W5MKR2 PTHR46679:SF1 FAMILY NOT NAMED GLUTAREDOXIN-2, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036 LEPOC|Ensembl=ENSLOCG00000000636.1|UniProtKB=W5LX73 W5LX73 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007885.1|UniProtKB=W5MMG8 W5MMG8 PTHR21404:SF3 HEN1 SMALL RNA 2'-O-METHYLTRANSFERASE LEPOC|Ensembl=ENSLOCG00000003504.1|UniProtKB=W5M728 W5M728 PTHR31691:SF1 ROTATIN ROTATIN cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;cell projection organization#GO:0030030;centriole replication#GO:0007099;organelle assembly#GO:0070925;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;centriole#GO:0005814;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000004561.1|UniProtKB=W5MAQ1 W5MAQ1 PTHR45682:SF10 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 13B phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000007959.1|UniProtKB=W5MMT1 W5MMT1 PTHR46029:SF3 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN 2 transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 LEPOC|Ensembl=ENSLOCG00000005612.1|UniProtKB=W5MEI0 W5MEI0 PTHR14002:SF10 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1-RELATED cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009357.1|UniProtKB=W5MSR4 W5MSR4 PTHR13748:SF31 COBW-RELATED ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1A-RELATED zinc ion binding#GO:0008270;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;molecular carrier activity#GO:0140104;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000009946.1|UniProtKB=W5MUV3 W5MUV3 PTHR21522:SF19 PROTON CHANNEL OTOP PROTON CHANNEL OTOP1 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;identical protein binding#GO:0042802;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;binding#GO:0005488 inner ear morphogenesis#GO:0042472;inner ear development#GO:0048839;cellular process#GO:0009987;multicellular organismal process#GO:0032501;tissue development#GO:0009888;monoatomic cation transmembrane transport#GO:0098655;embryo development#GO:0009790;monoatomic ion transmembrane transport#GO:0034220;sensory organ development#GO:0007423;developmental process#GO:0032502;transport#GO:0006810;proton transmembrane transport#GO:1902600;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;establishment of localization#GO:0051234;anatomical structure formation involved in morphogenesis#GO:0048646;anatomical structure morphogenesis#GO:0009653;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;animal gross anatomical part developmental process#GO:0160108;biomineral tissue development#GO:0031214;embryonic organ development#GO:0048568;localization#GO:0051179;monoatomic cation transport#GO:0006812;anatomical structure development#GO:0048856;transmembrane transport#GO:0055085;ear development#GO:0043583;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014435.1|UniProtKB=W5NAY2 W5NAY2 PTHR24416:SF658 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN-LIKE GROWTH FACTOR 1A RECEPTOR ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 glucose homeostasis#GO:0042593;regulation of JNK cascade#GO:0046328;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;chemical homeostasis#GO:0048878;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to hormone#GO:0009725;positive regulation of signaling#GO:0023056;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;cellular response to endogenous stimulus#GO:0071495;insulin-like growth factor receptor signaling pathway#GO:0048009;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;carbohydrate homeostasis#GO:0033500;response to endogenous stimulus#GO:0009719;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cellular response to insulin stimulus#GO:0032869;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;positive regulation of response to stimulus#GO:0048584;cellular response to nitrogen compound#GO:1901699;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;homeostatic process#GO:0042592;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;positive regulation of signal transduction#GO:0009967 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;transferase complex#GO:1990234;protein kinase complex#GO:1902911;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;axon#GO:0030424;transferase complex, transferring phosphorus-containing groups#GO:0061695 transmembrane signal receptor#PC00197 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885 LEPOC|Ensembl=ENSLOCG00000003444.1|UniProtKB=W5M6U2 W5M6U2 PTHR24072:SF311 RHO FAMILY GTPASE MITOCHONDRIAL RHO GTPASE 2 hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787 cellular component organization#GO:0016043;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;response to stimulus#GO:0050896;signaling#GO:0023052;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;regulation of membrane permeability#GO:0090559;organelle transport along microtubule#GO:0072384;apoptotic mitochondrial changes#GO:0008637;cytoskeleton organization#GO:0007010;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;microtubule-based movement#GO:0007018;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;organelle localization#GO:0051640;actin filament-based process#GO:0030029;localization#GO:0051179;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;regulation of mitochondrial membrane permeability#GO:0046902;biological regulation#GO:0065007;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;apoptotic signaling pathway#GO:0097190;establishment of localization#GO:0051234;mitochondrion localization#GO:0051646;actin filament organization#GO:0007015 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;plasma membrane#GO:0005886;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;cell periphery#GO:0071944;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000013796.1|UniProtKB=W5N8Q8 W5N8Q8 F8 PTHR24543:SF320 MULTICOPPER OXIDASE-RELATED COAGULATION FACTOR VIII gene expression#GO:0010467;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to wounding#GO:0009611;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;coagulation#GO:0050817;macromolecule metabolic process#GO:0043170;blood coagulation#GO:0007596;metabolic process#GO:0008152;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;hemostasis#GO:0007599;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;protein activation cascade#GO:0072376;wound healing#GO:0042060;regulation of biological quality#GO:0065008;blood coagulation, fibrin clot formation#GO:0072378 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidoreductase#PC00176 Blood coagulation#P00011>FVIII#P00405;Blood coagulation#P00011>FVIIIa#P00446 LEPOC|Ensembl=ENSLOCG00000003948.1|UniProtKB=W5M8K8 W5M8K8 PTHR13204:SF1 PTD012 PROTEIN BETA-KETO L-GULONATE DECARBOXYLASE transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;zinc ion binding#GO:0008270 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015772.1|UniProtKB=W5NFK7 W5NFK7 PTHR15034:SF7 DEATH DOMAIN-CONTAINING PROTEIN CRADD CASP2 AND RIPK1 DOMAIN-CONTAINING ADAPTOR WITH DEATH DOMAIN-RELATED positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction by p53 class mediator#GO:0072331;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012503.1|UniProtKB=W5N446 W5N446 PTHR22605:SF18 RZ-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF213-ALPHA-RELATED ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 circulatory system development#GO:0072359;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;blood vessel morphogenesis#GO:0048514;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;angiogenesis#GO:0001525;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;system development#GO:0048731;negative regulation of Wnt signaling pathway#GO:0030178;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;tube development#GO:0035295;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000009421.1|UniProtKB=W5MSY8 W5MSY8 PTHR35353:SF1 OSTEOCRIN OSTEOCRIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000017628.1|UniProtKB=W5NM74 W5NM74 PTHR11462:SF7 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JUND sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;response to steroid hormone#GO:0048545;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell cycle#GO:0051726;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to lipid#GO:0033993;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;positive regulation of transcription by RNA polymerase II#GO:0045944 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Jund#P06764;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838 LEPOC|Ensembl=ENSLOCG00000016811.1|UniProtKB=W5NJG7 W5NJG7 PTHR14154:SF3 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;intracellular transport#GO:0046907;transport#GO:0006810;carboxylic acid transport#GO:0046942;mitochondrial transmembrane transport#GO:1990542;organic acid transport#GO:0015849;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;monocarboxylic acid transport#GO:0015718 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004581.1|UniProtKB=W5MAS3 W5MAS3 PTHR14464:SF4 EXONUCLEASE V EXONUCLEASE V hydrolase activity#GO:0016787;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;exonuclease activity#GO:0004527;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 response to stimulus#GO:0050896;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000009611.1|UniProtKB=W5MTN4 W5MTN4 PTHR11753:SF4 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-4 COMPLEX SUBUNIT SIGMA-1 transport#GO:0006810;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000007270.1|UniProtKB=W5MK85 W5MK85 PTHR28525:SF1 REACTIVE OXYGEN SPECIES MODULATOR 1 REACTIVE OXYGEN SPECIES MODULATOR 1 protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;organelle organization#GO:0006996;protein import into mitochondrial matrix#GO:0030150;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;mitochondrial protein import pathway#GO:7770058;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866 LEPOC|Ensembl=ENSLOCG00000002099.1|UniProtKB=W5M222 W5M222 PTHR23226:SF438 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 436 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013055.1|UniProtKB=W5N626 W5N626 PTHR48013:SF12 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>MKK3,6#P00540;Ras Pathway#P04393>MKK3/6#P04568;Gonadotropin-releasing hormone receptor pathway#P06664>MKK3/6#P06805;FGF signaling pathway#P00021>MKK3,6#P00625;CCKR signaling map#P06959>MAP2K6#P07233;Oxidative stress response#P00046>MKK3/6#P01121;p38 MAPK pathway#P05918>MKK6#P06032 LEPOC|Ensembl=ENSLOCG00000003827.1|UniProtKB=W5M885 W5M885 PTHR48094:SF25 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED PARKINSON DISEASE PROTEIN 7 HOMOLOG lyase activity#GO:0016829;oxidoreductase activity#GO:0016491;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;detoxification#GO:0098754;aldehyde catabolic process#GO:0046185;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;alcohol biosynthetic process#GO:0046165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;response to stress#GO:0006950;response to oxidative stress#GO:0006979;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule catabolic process#GO:0044282;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;response to toxic substance#GO:0009636;carboxylic acid biosynthetic process#GO:0046394;cellular response to stimulus#GO:0051716;cellular detoxification of aldehyde#GO:0110095;monocarboxylic acid metabolic process#GO:0032787;ketone metabolic process#GO:0042180;carboxylic acid metabolic process#GO:0019752;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000009850.1|UniProtKB=W5MUI2 W5MUI2 PTHR22591:SF2 XIN XIN ACTIN-BINDING REPEAT-CONTAINING PROTEIN 1 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;membraneless organelle#GO:0043228;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stress fiber#GO:0001725;intracellular membraneless organelle#GO:0043232;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actomyosin#GO:0042641;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000005315.1|UniProtKB=W5MDK5 W5MDK5 PTHR24023:SF987 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXIV) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000015379.1|UniProtKB=W5NE69 W5NE69 PTHR21532:SF0 PHOSPHODIESTERASE HL CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary base#GO:0097546;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015442.1|UniProtKB=W5NEE8 W5NEE8 PTHR21678:SF6 GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88 R3H AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010815.1|UniProtKB=W5MXZ8 W5MXZ8 PTHR45875:SF1 METHYLTRANSFERASE N6AMT1 METHYLTRANSFERASE HEMK2 protein methyltransferase activity#GO:0008276;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;methyltransferase complex#GO:0034708;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000002218.1|UniProtKB=W5M2H4 W5M2H4 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011241.1|UniProtKB=W5MZK8 W5MZK8 PTHR23294:SF0 ET TRANSLATION PRODUCT-RELATED UNC93-LIKE PROTEIN MFSD11 LEPOC|Ensembl=ENSLOCG00000013051.1|UniProtKB=W5N627 W5N627 PTHR23169:SF26 ENVOPLAKIN DESMOPLAKIN skin development#GO:0043588;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;response to wounding#GO:0009611;cell-cell adhesion#GO:0098609;response to stress#GO:0006950;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;developmental process#GO:0032502;intermediate filament cytoskeleton organization#GO:0045104;response to stimulus#GO:0050896;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;wound healing#GO:0042060;intermediate filament-based process#GO:0045103;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155 cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;cell-cell contact zone#GO:0044291;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intercalated disc#GO:0014704;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000017424.1|UniProtKB=W5NLM0 W5NLM0 PTHR20661:SF0 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN GLUCOSAMINYL-PHOSPHATIDYLINOSITOL-ACYLTRANSFERASE PIGW acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000014760.1|UniProtKB=W5NC17 W5NC17 PTHR46448:SF2 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN PROTEIN KINASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008218.1|UniProtKB=W5MNL9 W5MNL9 PTHR45710:SF8 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN CONTAINING 5A-RELATED cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016904.1|UniProtKB=W5NJU0 W5NJU0 PTHR46896:SF1 SENTRIN-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 6 hydrolase activity#GO:0016787;ubiquitin-like protein peptidase activity#GO:0019783;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;macromolecule metabolic process#GO:0043170;regulation of organelle assembly#GO:1902115;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;post-translational protein modification#GO:0043687;regulation of microtubule cytoskeleton organization#GO:0070507;protein modification by small protein conjugation or removal#GO:0070647;regulation of microtubule-based process#GO:0032886;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of spindle assembly#GO:0090169;protein modification process#GO:0036211;regulation of protein-containing complex assembly#GO:0043254;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of spindle organization#GO:0090224;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000009827.1|UniProtKB=W5MUF4 W5MUF4 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of protein metabolic process#GO:0051248;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of protein metabolic process#GO:0051246;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071 mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088 LEPOC|Ensembl=ENSLOCG00000002817.1|UniProtKB=W5M4K9 W5M4K9 PTHR12570:SF14 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED NIPA-LIKE PROTEIN 3 establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;magnesium ion transport#GO:0015693;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000010207.1|UniProtKB=W5MVU0 W5MVU0 PTHR14338:SF8 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1 regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytosol#GO:0005829;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000016612.1|UniProtKB=W5NIR8 W5NIR8 PTHR45833:SF1 METHIONINE SYNTHASE METHIONINE SYNTHASE transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740 proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;sulfur compound metabolic process#GO:0006790;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 S-adenosylmethionine biosynthesis#P02773>Cobalamin-dependent homocysteine transmethylase#P03142;Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953;Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024 LEPOC|Ensembl=ENSLOCG00000004426.1|UniProtKB=W5MA83 W5MA83 PTHR24253:SF196 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 7 catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012382.1|UniProtKB=W5N3N8 W5N3N8 PTHR14076:SF10 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RAMP2 PROTEIN coreceptor activity#GO:0015026;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;vesicle-mediated transport#GO:0016192;receptor internalization#GO:0031623;response to hormone#GO:0009725;establishment of protein localization#GO:0045184;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;import into cell#GO:0098657;anatomical structure formation involved in morphogenesis#GO:0048646;calcium ion transport#GO:0006816;vasculature development#GO:0001944;protein localization to cell periphery#GO:1990778;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;endocytosis#GO:0006897;signaling#GO:0023052;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular localization#GO:0051641;angiogenesis#GO:0001525;monoatomic ion transport#GO:0006811;protein transport#GO:0015031;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;developmental process#GO:0032502;transport#GO:0006810;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;protein localization to plasma membrane#GO:0072659;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;localization within membrane#GO:0051668 signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005466.1|UniProtKB=W5MDY1 W5MDY1 PTHR23507:SF2 ZGC:174356 PROTON-COUPLED FOLATE TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011655.1|UniProtKB=W5N113 W5N113 PTHR24393:SF185 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 76 sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008511.1|UniProtKB=W5MPP8 W5MPP8 PTHR45691:SF18 PROTEIN DIAPHANOUS FH2 DOMAIN-CONTAINING PROTEIN 1 supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000018329.1|UniProtKB=W5NP71 W5NP71 PTHR23401:SF1 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;molecular function activator activity#GO:0140677;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase activator activity#GO:0030295;kinase activator activity#GO:0019209 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;brain development#GO:0007420;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;anatomical structure development#GO:0048856;system development#GO:0048731;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;head development#GO:0060322;neuron projection development#GO:0031175;cellular process#GO:0009987;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;axon#GO:0030424;growth cone#GO:0030426 kinase activator#PC00138;kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000004998.1|UniProtKB=W5MCA7 W5MCA7 PTHR12190:SF1 A-KINASE ANCHOR PROTEIN AKAP 8 DBIRD COMPLEX SUBUNIT ZNF326 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription elongation#GO:0032784;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016340.1|UniProtKB=W5NHR4 W5NHR4 PTHR10552:SF11 U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A' nucleic acid binding#GO:0003676;binding#GO:0005488;snRNA binding#GO:0017069;RNA binding#GO:0003723 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;U2 snRNP#GO:0005686;intracellular organelle#GO:0043229;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000016194.1|UniProtKB=W5NH52 W5NH52 PTHR21258:SF40 DOCKING PROTEIN RELATED FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 2 fibroblast growth factor receptor binding#GO:0005104;molecular adaptor activity#GO:0060090;growth factor receptor binding#GO:0070851;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;binding#GO:0005488;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;response to fibroblast growth factor#GO:0071774;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543 cell-cell junction#GO:0005911;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>FRS-2#P00240;FGF signaling pathway#P00021>FRS2#P00635 LEPOC|Ensembl=ENSLOCG00000005299.1|UniProtKB=W5MDC1 W5MDC1 PTHR11955:SF150 FATTY ACID BINDING PROTEIN ADIPOCYTE FATTY ACID-BINDING PROTEIN-RELATED small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;lipid binding#GO:0008289 lipid transport#GO:0006869;macromolecule localization#GO:0033036;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;lipid localization#GO:0010876 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000015187.1|UniProtKB=W5NDH8 W5NDH8 PTHR22811:SF38 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043 cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009772.1|UniProtKB=W5MUA8 W5MUA8 PTHR14166:SF8 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 3 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;system development#GO:0048731;regulation of synapse structure or activity#GO:0050803;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;animal gross anatomical part developmental process#GO:0160108;regulation of locomotion#GO:0040012;nervous system development#GO:0007399;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;multicellular organism development#GO:0007275;regulation of cell migration#GO:0030334;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000009312.1|UniProtKB=W5MSJ9 W5MSJ9 PTHR15919:SF12 DAPPER-RELATED DAPPER HOMOLOG 1 regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of JNK cascade#GO:0046328;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Wnt signaling pathway#P00057>Frodo#P01470;Wnt signaling pathway#P00057>Dapper#P01469 LEPOC|Ensembl=ENSLOCG00000013768.1|UniProtKB=W5N8L7 W5N8L7 PTHR10985:SF8 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY AND ENHANCER OF SPLIT-RELATED PROTEIN HELT RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 pattern specification process#GO:0007389;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;Notch signaling pathway#GO:0007219;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of multicellular organismal process#GO:0051239 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000004311.1|UniProtKB=W5M9W5 W5M9W5 PTHR19134:SF203 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;response to stimulus#GO:0050896;cell adhesion#GO:0007155;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;synaptic membrane adhesion#GO:0099560;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006036.1|UniProtKB=W5MFY7 W5MFY7 PTHR10199:SF121 THROMBOSPONDIN THROMBOSPONDIN-4-B structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011781.1|UniProtKB=W5N1H9 W5N1H9 PTHR11346:SF179 GALECTIN GALECTIN binding#GO:0005488;oligosaccharide binding#GO:0070492;laminin binding#GO:0043236;extracellular matrix binding#GO:0050840;carbohydrate binding#GO:0030246;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;mononuclear cell migration#GO:0071674;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;positive chemotaxis#GO:0050918;cellular process#GO:0009987;positive regulation of transport#GO:0051050;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;granulocyte migration#GO:0097530;neutrophil migration#GO:1990266;response to chemical#GO:0042221;taxis#GO:0042330;negative regulation of signal transduction#GO:0009968;neutrophil chemotaxis#GO:0030593;regulation of apoptotic process#GO:0042981;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;negative regulation of cellular component organization#GO:0051129;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;negative regulation of transport#GO:0051051;regulation of metal ion transport#GO:0010959;locomotion#GO:0040011;regulation of cell communication#GO:0010646;regulation of apoptotic signaling pathway#GO:2001233;chemotaxis#GO:0006935;negative regulation of apoptotic signaling pathway#GO:2001234;macrophage chemotaxis#GO:0048246;cell chemotaxis#GO:0060326;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of response to stimulus#GO:0048585;cell migration#GO:0016477;regulation of monoatomic ion transport#GO:0043269;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;leukocyte migration#GO:0050900;regulation of response to stimulus#GO:0048583;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;nucleus#GO:0005634;external encapsulating structure#GO:0030312;membrane#GO:0016020;extracellular matrix#GO:0031012;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000014965.1|UniProtKB=W5NCR5 W5NCR5 PTHR21083:SF1 TWISTER DYNEIN AXONEMAL ASSEMBLY FACTOR 6 binding#GO:0005488;protein binding#GO:0005515 cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;reproductive process#GO:0022414;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001190.1|UniProtKB=W5LYY7 W5LYY7 PTHR12773:SF0 UPF0315 PROTEIN-RELATED MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000014610.1|UniProtKB=W5NBI0 W5NBI0 PTHR24348:SF65 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK3 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular component assembly#GO:0022607;macroautophagy#GO:0016236;biological regulation#GO:0065007;reticulophagy#GO:0061709;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;cellular component biogenesis#GO:0044085;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;regulation of catabolic process#GO:0009894;autophagosome assembly#GO:0000045;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896;piecemeal microautophagy of the nucleus#GO:0034727;cellular component organization#GO:0016043;response to starvation#GO:0042594;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008525.1|UniProtKB=W5MPR5 W5MPR5 PTHR12141:SF4 ARFAPTIN-RELATED ARFAPTIN-1 molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;regulation of actin filament-based process#GO:0032970;intracellular transport#GO:0046907;regulation of actin nucleation#GO:0051125;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179 Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000005177.1|UniProtKB=W5MCX5 W5MCX5 PTHR36464:SF1 PROTEIN BEAN1 PROTEIN BEAN1 LEPOC|Ensembl=ENSLOCG00000012202.1|UniProtKB=W5N311 W5N311 PTHR16004:SF3 RING FINGER PROTEIN 31-RELATED SI:DKEY-181M9.8 modification-dependent protein binding#GO:0140030;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;polyubiquitin modification-dependent protein binding#GO:0031593;transferase activity#GO:0016740;catalytic activity#GO:0003824;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;ubiquitin binding#GO:0043130;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009734.1|UniProtKB=W5MU30 W5MU30 PTHR10824:SF42 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COA THIOESTERASE 20-RELATED thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617;hydrolase activity#GO:0016787 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000017996.1|UniProtKB=W5NN88 W5NN88 PTHR12871:SF3 BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE II ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000013678.1|UniProtKB=W5N8A4 W5N8A4 PTHR11086:SF23 DEOXYCYTIDYLATE DEAMINASE-RELATED DEOXYCYTIDYLATE DEAMINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;nucleoside monophosphate biosynthetic process#GO:0009124;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;deaminase#PC00088 LEPOC|Ensembl=ENSLOCG00000016726.1|UniProtKB=W5NJ57 W5NJ57 PTHR12990:SF9 ARMET-LIKE PROTEIN CEREBRAL DOPAMINE NEUROTROPHIC FACTOR growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular component organization#GO:0016043;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000306.1|UniProtKB=W5LW26 W5LW26 PTHR11453:SF37 ANION EXCHANGE PROTEIN ELECTRONEUTRAL SODIUM BICARBONATE EXCHANGER 1 symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000000559.1|UniProtKB=W5LWW3 W5LWW3 PTHR19282:SF168 TETRASPANIN TETRASPANIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014495.1|UniProtKB=W5NB40 W5NB40 PTHR15076:SF12 CD99/MIC2 PROTEIN RELATED CD99 ANTIGEN-LIKE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000016619.1|UniProtKB=W5NIS0 W5NIS0 PTHR11915:SF429 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-2 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization#GO:0016043;muscle cell differentiation#GO:0042692;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular organelle#GO:0043229;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;sarcomere#GO:0030017;membraneless organelle#GO:0043228;I band#GO:0031674;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;cell periphery#GO:0071944;membrane#GO:0016020 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 LEPOC|Ensembl=ENSLOCG00000001398.1|UniProtKB=W5LZN0 W5LZN0 PTHR21311:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8 establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;retrograde transport, vesicle recycling within Golgi#GO:0000301;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;COG complex#GO:0017119;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007651.1|UniProtKB=W5MLM2 W5MLM2 PTHR12046:SF0 HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000013344.1|UniProtKB=W5N754 W5N754 PTHR11269:SF8 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 1 transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;protein binding#GO:0005515;transcription factor binding#GO:0008134;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 rhythmic process#GO:0048511;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to abiotic stimulus#GO:0009628;circadian regulation of gene expression#GO:0032922;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;photoperiodism#GO:0009648;negative regulation of cellular process#GO:0048523;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;response to radiation#GO:0009314;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Gonadotropin-releasing hormone receptor pathway#P06664>mPer1#G06895;Gonadotropin-releasing hormone receptor pathway#P06664>mPer1#G06681;Circadian clock system#P00015>Per#P00504;Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>per#G01499 LEPOC|Ensembl=ENSLOCG00000007444.1|UniProtKB=W5MKW9 W5MKW9 PTHR23349:SF5 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR SCLERAXIS sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002643.1|UniProtKB=W5M412 W5M412 PTHR18902:SF26 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED GOLGIN SUBFAMILY A MEMBER 3 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000014240.1|UniProtKB=W5NA74 W5NA74 PTHR12801:SF160 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED APOPTOSIS-ENHANCING NUCLEASE nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 exoribonuclease#PC00099;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017863.1|UniProtKB=W5NMV7 W5NMV7 PTHR11467:SF36 HISTONE H1 H1.010 LINKER HISTONE, CLUSTER MEMBER-RELATED chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;nucleosome binding#GO:0031491;double-stranded DNA binding#GO:0003690;protein-containing complex binding#GO:0044877;DNA binding#GO:0003677 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;regulation of DNA recombination#GO:0000018;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000014853.1|UniProtKB=W5NCC9 W5NCC9 PTHR45820:SF1 FI23527P1 PROTON-COUPLED ZINC ANTIPORTER SLC30A1 monoatomic cation transmembrane transporter activity#GO:0008324;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;transporter regulator activity#GO:0141108;transition metal ion transmembrane transporter activity#GO:0046915;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator activity#GO:0098772;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;zinc ion transmembrane transporter activity#GO:0005385;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246 monoatomic ion homeostasis#GO:0050801;detoxification of inorganic compound#GO:0061687;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;monoatomic cation transmembrane transport#GO:0098655;detoxification#GO:0098754;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;response to metal ion#GO:0010038;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;homeostatic process#GO:0042592;metal ion transport#GO:0030001;zinc ion transmembrane transport#GO:0071577;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000005204.1|UniProtKB=W5MD04 W5MD04 PTHR21184:SF3 MENORIN (DENDRITIC BRANCHING PROTEIN) PROTEIN FAM151B cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000005314.1|UniProtKB=W5MDE5 W5MDE5 PTHR11547:SF19 ARGININE OR CREATINE KINASE CREATINE KINASE S-TYPE, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;amino acid kinase#PC00045 LEPOC|Ensembl=ENSLOCG00000001107.1|UniProtKB=W5LYN6 W5LYN6 PTHR16294:SF4 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN DOMAIN-CONTAINING PROTEIN 1 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 LEPOC|Ensembl=ENSLOCG00000017113.1|UniProtKB=W5NKI7 W5NKI7 PTHR32261:SF8 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 5 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016145.1|UniProtKB=W5NGZ1 W5NGZ1 PTHR11141:SF10 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23B enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000007498.1|UniProtKB=W5ML43 W5ML43 PTHR12125:SF11 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 2 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003708.1|UniProtKB=W5M7U8 W5M7U8 PTHR13251:SF3 EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000010026.1|UniProtKB=W5MV59 W5MV59 PTHR45752:SF58 LEUCINE-RICH REPEAT-CONTAINING PH DOMAIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN PHOSPHATASE 1 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011073.1|UniProtKB=W5MYY5 W5MYY5 PTHR22883:SF213 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC22 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096 protein targeting#GO:0006605;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;developmental maturation#GO:0021700;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein targeting to membrane#GO:0006612;developmental process#GO:0032502 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007553.1|UniProtKB=W5MLA6 W5MLA6 PTHR10046:SF24 ATP DEPENDENT LON PROTEASE FAMILY MEMBER LON PROTEASE HOMOLOG 2, PEROXISOMAL catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;localization#GO:0051179;proteolysis#GO:0006508;protein targeting#GO:0006605;primary metabolic process#GO:0044238;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;establishment of protein localization#GO:0045184 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000002423.1|UniProtKB=W5M393 W5M393 PTHR32019:SF2 R3H DOMAIN-CONTAINING PROTEIN 4 R3H DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000005054.1|UniProtKB=W5MCH5 W5MCH5 PTHR24418:SF224 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FGR protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;signaling#GO:0023052;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230 LEPOC|Ensembl=ENSLOCG00000005673.1|UniProtKB=W5MEP4 W5MEP4 PTHR10822:SF8 GLYPICAN GLYPICAN-1 binding#GO:0005488;fibroblast growth factor binding#GO:0017134;protein binding#GO:0005515;growth factor binding#GO:0019838 regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;cell migration#GO:0016477;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of protein localization to membrane#GO:1905475;negative regulation of cell communication#GO:0010648;regulation of protein localization#GO:0032880;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cell surface#GO:0009986;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013117.1|UniProtKB=W5N696 W5N696 PTHR14256:SF3 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE ASSOCIATED SUBUNIT FA4L3 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006897.1|UniProtKB=W5MIY5 W5MIY5 PTHR46465:SF2 LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG negative regulation of cell communication#GO:0010648;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;negative regulation of biological process#GO:0048519 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;early endosome membrane#GO:0031901;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000016469.1|UniProtKB=W5NI84 W5NI84 PTHR23227:SF87 BUCENTAUR RELATED PROTEIN CFDP2 LEPOC|Ensembl=ENSLOCG00000011369.1|UniProtKB=W5N012 W5N012 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009787.1|UniProtKB=W5MUA3 W5MUA3 PTHR12027:SF92 WNT RELATED PROTEIN WNT-8A protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;system development#GO:0048731;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000003743.1|UniProtKB=W5M7U9 W5M7U9 PTHR12974:SF46 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5B nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000012265.1|UniProtKB=W5N382 W5N382 PTHR17614:SF11 ZINC FINGER-CONTAINING G PATCH DOMAIN-CONTAINING PROTEIN 8 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003686.1|UniProtKB=W5M7L8 W5M7L8 PTHR13531:SF4 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 17B plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 cilium#GO:0005929;ciliary transition zone#GO:0035869;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006362.1|UniProtKB=W5MH17 W5MH17 PTHR46536:SF1 ARL14 EFFECTOR PROTEIN ARL14 EFFECTOR PROTEIN LEPOC|Ensembl=ENSLOCG00000014885.1|UniProtKB=W5NCH2 W5NCH2 PTHR24072:SF394 RHO FAMILY GTPASE RAS HOMOLOG FAMILY MEMBER UB hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787 signaling#GO:0023052;response to stimulus#GO:0050896;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;localization#GO:0051179;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000006330.1|UniProtKB=W5MGY3 W5MGY3 PTHR46660:SF2 FAMILY NOT NAMED GLYCOSYLTRANSFERASE 1 DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000005578.1|UniProtKB=W5MEC2 W5MEC2 PTHR10876:SF7 ZINC FINGER PROTEIN ZPR1 ZINC FINGER PROTEIN ZPR1 protein binding#GO:0005515;binding#GO:0005488 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770 LEPOC|Ensembl=ENSLOCG00000002427.1|UniProtKB=W5M394 W5M394 PTHR23233:SF19 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000000048.1|UniProtKB=W5LVA0 W5LVA0 PTHR14519:SF8 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 coagulation#GO:0050817;cellular process#GO:0009987;ketone metabolic process#GO:0042180;response to stress#GO:0006950;hemostasis#GO:0007599;response to wounding#GO:0009611;vitamin K metabolic process#GO:0042373;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;multicellular organismal process#GO:0032501;metabolic process#GO:0008152;regulation of biological quality#GO:0065008;blood coagulation#GO:0007596;wound healing#GO:0042060 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012350.1|UniProtKB=W5N3J8 W5N3J8 PTHR15528:SF10 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;multicellular organismal-level homeostasis#GO:0048871;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;positive regulation of RNA metabolic process#GO:0051254 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011252.1|UniProtKB=W5MZL2 W5MZL2 PTHR23147:SF22 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 2 membraneless organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000004024.1|UniProtKB=W5M8V0 W5M8V0 PTHR11266:SF134 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 PEROXISOMAL MEMBRANE PROTEIN 2 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008208.1|UniProtKB=W5MNK5 W5MNK5 PTHR46881:SF1 PALMDELPHIN PALMDELPHIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000007278.1|UniProtKB=W5MKA4 W5MKA4 PTHR11977:SF86 VILLIN SUPERVILLIN A ISOFORM 1 ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;phosphatidylinositol phosphate binding#GO:1901981 regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;actin filament-based process#GO:0030029;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of actin filament depolymerization#GO:0030834 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000011495.1|UniProtKB=W5N0G7 W5N0G7 PTHR23235:SF17 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP4 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000004674.1|UniProtKB=W5MB36 W5MB36 PTHR12080:SF59 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE HEPATIC AND GLIAL CELL ADHESION MOLECULE molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;immune response#GO:0006955;cell communication#GO:0007154;localization#GO:0051179;intracellular protein localization#GO:0008104;immune system process#GO:0002376;protein localization to cell junction#GO:1902414 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011302.1|UniProtKB=W5MZT1 W5MZT1 PTHR45941:SF5 ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2-LIKE-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2 glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 LEPOC|Ensembl=ENSLOCG00000002095.1|UniProtKB=W5M223 W5M223 PTHR44436:SF1 F-BOX/WD REPEAT-CONTAINING PROTEIN 2 F-BOX_WD REPEAT-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000005577.1|UniProtKB=W5MEE0 W5MEE0 PTHR11689:SF158 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)_CL(-) EXCHANGE TRANSPORTER 6 voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 chloride transport#GO:0006821;monoatomic anion transport#GO:0006820;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;lysosomal membrane#GO:0005765;endomembrane system#GO:0012505;late endosome#GO:0005770;vacuole#GO:0005773;cytoplasm#GO:0005737 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000003372.1|UniProtKB=W5M6H7 W5M6H7 PTHR12015:SF186 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 25 cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000011451.1|UniProtKB=W5N0B4 W5N0B4 PTHR46135:SF5 NME/NM23 FAMILY MEMBER 8 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 6 ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000012663.1|UniProtKB=W5N4M7 W5N4M7 PTHR45627:SF5 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849 nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cyclic nucleotide biosynthetic process#GO:0009190;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 adenylate cyclase#PC00043 LEPOC|Ensembl=ENSLOCG00000015737.1|UniProtKB=W5NFG7 W5NFG7 PTHR42752:SF1 IMIDAZOLONEPROPIONASE IMIDAZOLONEPROPIONASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000013303.1|UniProtKB=W5N6Y6 W5N6Y6 PTHR12900:SF0 MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 CHECKPOINT PROTEIN cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle G2/M phase transition#GO:1902750;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;negative regulation of mitotic cell cycle phase transition#GO:1901991;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;biological regulation#GO:0065007;regulation of G2/M transition of mitotic cell cycle#GO:0010389;telomere organization#GO:0032200;sexual reproduction#GO:0019953;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA recombination#GO:0006310;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;signaling#GO:0023052;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;mitotic DNA replication checkpoint signaling#GO:0033314;telomere maintenance#GO:0000723;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;recombinational repair#GO:0000725;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic DNA damage checkpoint signaling#GO:0044773 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;site of double-strand break#GO:0035861;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007645.1|UniProtKB=W5MLL3 W5MLL3 PTHR10665:SF2 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS-LIKE PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Notch signaling pathway#P00045>Su(H)#P01101;Angiogenesis#P00005>CSL#P00233 LEPOC|Ensembl=ENSLOCG00000020987.1|UniProtKB=Q8HQM8 Q8HQM8 PTHR11410:SF0 ATP SYNTHASE SUBUNIT A ATP SYNTHASE F(0) COMPLEX SUBUNIT A monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;organophosphate biosynthetic process#GO:0090407;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164 cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;proton-transporting ATP synthase complex#GO:0045259;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP synthase#PC00002 ATP synthesis#P02721>ATP synthetase F0#P02797 LEPOC|Ensembl=ENSLOCG00000002201.1|UniProtKB=W5M2J0 W5M2J0 PTHR10218:SF233 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(OLF) SUBUNIT ALPHA hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 biological regulation#GO:0065007;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212;system process#GO:0003008;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;sensory perception of chemical stimulus#GO:0007606;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552 heterotrimeric G-protein#PC00117;G-protein#PC00020 Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gsalpha#P00705;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Endothelin signaling pathway#P00019>Gs#P00584;Enkephalin release#P05913>G-Protein (s)#P05977 LEPOC|Ensembl=ENSLOCG00000002588.1|UniProtKB=W5M3V2 W5M3V2 PTHR45635:SF13 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE 3 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000001302.1|UniProtKB=W5LZC3 W5LZC3 PTHR11850:SF97 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 3 transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 cell development#GO:0048468;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;eye development#GO:0001654;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;embryo development#GO:0009790;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;sensory system development#GO:0048880;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;visual system development#GO:0150063;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;embryonic organ development#GO:0048568;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009546.1|UniProtKB=W5MTF6 W5MTF6 PTHR12606:SF30 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 1 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015241.1|UniProtKB=W5NDP5 W5NDP5 PTHR13087:SF0 NF-KAPPA B ACTIVATING PROTEIN NFKB ACTIVATING PROTEIN LIKE regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006802.1|UniProtKB=W5MIL6 W5MIL6 PTHR23287:SF18 RUBY-EYE2-LIKE PROTEIN BLOC-2 COMPLEX MEMBER HPS5 developmental pigmentation#GO:0048066;pigmentation#GO:0043473 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000016270.1|UniProtKB=W5NHG0 W5NHG0 PTHR12192:SF2 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2 LEPOC|Ensembl=ENSLOCG00000014501.1|UniProtKB=W5NB37 W5NB37 PTHR45736:SF8 ZINC FINGER MYM-TYPE PROTEIN TRANSCRIPTIONAL REGULATOR QRICH1 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001243.1|UniProtKB=W5LZ54 W5LZ54 PTHR31596:SF1 T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006712.1|UniProtKB=W5MI96 W5MI96 PTHR23067:SF12 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385D nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012903.1|UniProtKB=W5N5H8 W5N5H8 LSM5 PTHR20971:SF0 U6 SNRNA-ASSOCIATED PROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U6 snRNP#GO:0005688;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;Lsm2-8 complex#GO:0120115;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000015050.1|UniProtKB=W5ND13 W5ND13 PTHR11955:SF62 FATTY ACID BINDING PROTEIN CELLULAR RETINOIC ACID-BINDING PROTEIN 1 organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;lipid binding#GO:0008289;fatty acid binding#GO:0005504 lipid localization#GO:0010876;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;establishment of localization#GO:0051234;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;lipid transport#GO:0006869 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000000789.1|UniProtKB=W5LXM0 W5LXM0 PTHR14289:SF16 F-BOX ONLY PROTEIN 3 POLYMERASE DELTA-INTERACTING PROTEIN 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoid#GO:0009295;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial nucleoid#GO:0042645;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000001902.1|UniProtKB=W5M1F5 W5M1F5 PTHR10026:SF8 CYCLIN CYCLIN-H cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIIH holo complex#GO:0005675;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138;kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000004468.1|UniProtKB=W5MAE0 W5MAE0 PTHR45841:SF1 MRNA TURNOVER PROTEIN 4 MRTO4 MRNA TURNOVER PROTEIN 4 HOMOLOG RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000002959.1|UniProtKB=W5M531 W5M531 PTHR16074:SF4 BARDET-BIEDL SYNDROME 7 PROTEIN BBSOME COMPLEX MEMBER BBS7 localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;neuron projection#GO:0043005;protein-containing complex#GO:0032991;BBSome#GO:0034464;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intracellular organelle#GO:0043229;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013028.1|UniProtKB=W5N5Z0 W5N5Z0 PTHR21646:SF27 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 8 catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vesicle organization#GO:0016050;positive regulation of Wnt signaling pathway#GO:0030177;endomembrane system organization#GO:0010256;intracellular signaling cassette#GO:0141124;organelle organization#GO:0006996;regulation of canonical Wnt signaling pathway#GO:0060828;signal transduction#GO:0007165;regulation of protein stability#GO:0031647;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 postsynaptic density#GO:0014069;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;postsynapse#GO:0098794;midbody#GO:0030496;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;cytoplasm#GO:0005737 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000015445.1|UniProtKB=W5NEF8 W5NEF8 PTHR45817:SF1 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 2 catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 multicellular organismal process#GO:0032501;tube development#GO:0035295;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;developmental process#GO:0032502;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;cellular component organization#GO:0016043;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;external encapsulating structure organization#GO:0045229;system development#GO:0048731;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000006962.1|UniProtKB=W5MJ70 W5MJ70 PTHR10404:SF26 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE TRANSFERRIN RECEPTOR PROTEIN 1 peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000007590.1|UniProtKB=W5MLF0 W5MLF0 PTHR23310:SF62 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000005319.1|UniProtKB=W5MDF2 W5MDF2 PTHR31108:SF9 TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN TUMOR PROTEIN P63-REGULATED 1-LIKE cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012857.1|UniProtKB=W5N5C8 W5N5C8 PTHR23406:SF27 MALIC ENZYME-RELATED NAD-DEPENDENT MALIC ENZYME, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013741.1|UniProtKB=W5N8K4 W5N8K4 PTHR24072:SF124 RHO FAMILY GTPASE MITOCHONDRIAL RHO GTPASE 1 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924 apoptotic signaling pathway#GO:0097190;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;actin filament organization#GO:0007015;mitochondrion localization#GO:0051646;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;localization#GO:0051179;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;organelle localization#GO:0051640;actin filament-based process#GO:0030029;microtubule-based movement#GO:0007018;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of membrane permeability#GO:0090559;cytoskeleton organization#GO:0007010;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;organelle transport along microtubule#GO:0072384;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;cellular process#GO:0009987;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;microtubule-based transport#GO:0099111;response to stimulus#GO:0050896;establishment of organelle localization#GO:0051656;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;cell periphery#GO:0071944;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;organelle outer membrane#GO:0031968 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000013881.1|UniProtKB=W5N910 W5N910 PTHR24355:SF23 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000015375.1|UniProtKB=W5NE62 W5NE62 PTHR11252:SF0 POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527 RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000011484.1|UniProtKB=W5N0F5 W5N0F5 PTHR24205:SF14 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 1 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011018.1|UniProtKB=W5MYR1 W5MYR1 PTHR12241:SF162 TUBULIN POLYGLUTAMYLASE TUBULIN MONOGLUTAMYLASE TTLL4 catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000015374.1|UniProtKB=W5NE59 W5NE59 PTHR21485:SF3 HAD SUPERFAMILY MEMBERS CMAS AND KDSC N-ACYLNEURAMINATE CYTIDYLYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 transferase#PC00220;nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000006699.1|UniProtKB=W5MI84 W5MI84 PTHR19139:SF39 AQUAPORIN TRANSPORTER LENS FIBER MAJOR INTRINSIC PROTEIN passive transmembrane transporter activity#GO:0022803;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267 transport#GO:0006810;water transport#GO:0006833;localization#GO:0051179;establishment of localization#GO:0051234;fluid transport#GO:0042044 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011400.1|UniProtKB=W5N058 W5N058 PTHR24072:SF21 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHON purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rho#P00948 LEPOC|Ensembl=ENSLOCG00000011814.1|UniProtKB=W5N1N0 W5N1N0 PRLR PTHR23036:SF199 CYTOKINE RECEPTOR PROLACTIN RECEPTOR immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013217.1|UniProtKB=W5N6M5 W5N6M5 PTHR44490:SF1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme activator activity#GO:0008047;kinase activator activity#GO:0019209 positive regulation of signaling#GO:0023056;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of programmed cell death#GO:0043068;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 translation elongation factor#PC00222;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000008177.1|UniProtKB=W5MNG7 W5MNG7 PTHR10971:SF36 MRNA EXPORT FACTOR AND BUB3 MITOTIC CHECKPOINT PROTEIN BUB3 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell cycle#GO:0045786;negative regulation of chromosome segregation#GO:0051985;regulation of chromosome segregation#GO:0051983;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;negative regulation of chromosome organization#GO:2001251;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic sister chromatid separation#GO:0010965;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;negative regulation of chromosome separation#GO:1905819;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;condensed chromosome, centromeric region#GO:0000779;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010692.1|UniProtKB=W5MXJ2 W5MXJ2 PTHR13923:SF23 SEC31-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC31A cellular component organization#GO:0016043;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;COPII-coated vesicle budding#GO:0090114;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;coated membrane#GO:0048475;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;protein-containing complex#GO:0032991;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;cytoplasm#GO:0005737;vesicle coat#GO:0030120 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000002044.1|UniProtKB=W5M1W7 W5M1W7 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN DMBT1 cargo receptor activity#GO:0038024 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004784.1|UniProtKB=W5MBJ2 W5MBJ2 PTHR11616:SF133 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 import into cell#GO:0098657;establishment of localization#GO:0051234;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;glycine transport#GO:0015816;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000006027.1|UniProtKB=W5MFX1 W5MFX1 PTHR11875:SF67 TESTIS-SPECIFIC Y-ENCODED PROTEIN PROTEIN SET histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;protein binding#GO:0005515 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000015955.1|UniProtKB=W5NG87 W5NG87 PTHR10104:SF6 STATHMIN STATHMIN-4 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;supramolecular fiber organization#GO:0097435;regulation of microtubule-based process#GO:0032886;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;protein-containing complex disassembly#GO:0032984;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of microtubule polymerization or depolymerization#GO:0031110;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;protein depolymerization#GO:0051261;biological regulation#GO:0065007;microtubule polymerization or depolymerization#GO:0031109;cellular component disassembly#GO:0022411;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;neuron differentiation#GO:0030182;microtubule depolymerization#GO:0007019;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987 neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane bounded cell projection#GO:0120025 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 Cytoskeletal regulation by Rho GTPase#P00016>Op18/stathmin#P00513 LEPOC|Ensembl=ENSLOCG00000015875.1|UniProtKB=W5NG00 W5NG00 PTHR12166:SF7 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR 2 positive regulation of secretion#GO:0051047;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;localization#GO:0051179;secretion#GO:0046903;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;export from cell#GO:0140352;regulation of cellular process#GO:0050794;transport#GO:0006810;regulation of localization#GO:0032879;regulation of transport#GO:0051049;exocytosis#GO:0006887;establishment of localization#GO:0051234;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532;cellular process#GO:0009987;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192 synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008537.1|UniProtKB=W5MPS6 W5MPS6 PTHR13041:SF3 JTB PROTEIN-RELATED PROTEIN JTB cell division#GO:0051301;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cytokinesis#GO:0000910;mitotic cell cycle process#GO:1903047;cytoskeleton-dependent cytokinesis#GO:0061640 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000014111.1|UniProtKB=W5N9W6 W5N9W6 PTHR45628:SF11 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1D transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;transport#GO:0006810;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;calcium channel complex#GO:0034704 voltage-gated ion channel#PC00241 Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411 LEPOC|Ensembl=ENSLOCG00000002645.1|UniProtKB=W5M3Z5 W5M3Z5 PTHR45701:SF6 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 3 binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484 vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;organelle organization#GO:0006996;localization#GO:0051179;vesicle fusion#GO:0006906;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423 LEPOC|Ensembl=ENSLOCG00000007664.1|UniProtKB=W5MLR3 W5MLR3 PTHR11243:SF14 GROWTH FACTOR RECEPTOR-BOUND PROTEIN AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;signaling#GO:0023052;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016342.1|UniProtKB=W5NHR8 W5NHR8 PTHR10334:SF577 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN 3 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000009781.1|UniProtKB=W5MU92 W5MU92 PTHR24155:SF10 OSTEOCLAST-STIMULATING FACTOR 1 OSTEOCLAST-STIMULATING FACTOR 1 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000008094.1|UniProtKB=W5MN82 W5MN82 PTHR10105:SF3 SELENOPROTEIN P SELENOPROTEIN P extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009590.1|UniProtKB=W5MTM2 W5MTM2 PTHR45670:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE HECTD1 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005278.1|UniProtKB=W5MDA1 W5MDA1 PTHR45822:SF8 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 3 ISOFORM X2-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to fatty acid#GO:0071398;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to fatty acid#GO:0070542;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000010130.1|UniProtKB=W5MVJ1 W5MVJ1 PTHR11871:SF5 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B GAMMA ISOFORM phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 LEPOC|Ensembl=ENSLOCG00000011295.1|UniProtKB=W5MZS3 W5MZS3 PTHR28520:SF15 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 microtubule polymerization or depolymerization#GO:0031109;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;spindle organization#GO:0007051;chromosome organization#GO:0051276;microtubule polymerization#GO:0046785;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;supramolecular fiber organization#GO:0097435;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000007875.1|UniProtKB=W5MMH0 W5MMH0 PTHR12533:SF5 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;calcineurin-NFAT signaling cascade#GO:0033173;calcineurin-mediated signaling#GO:0097720;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;calcium-mediated signaling#GO:0019722;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;intracellular signaling cassette#GO:0141124;positive regulation of macromolecule metabolic process#GO:0010604;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Wnt signaling pathway#P00057>NFAT#P01452;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367;Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851 LEPOC|Ensembl=ENSLOCG00000013199.1|UniProtKB=W5N6K2 W5N6K2 PTHR10501:SF25 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B RNA-BINDING PROTEIN WITH MULTIPLE SPLICING RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000005596.1|UniProtKB=W5MEE7 W5MEE7 PTHR36855:SF1 CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE YALI0A20966P LEPOC|Ensembl=ENSLOCG00000002104.1|UniProtKB=W5M241 W5M241 PTHR22939:SF127 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA2, MITOCHONDRIAL serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of apoptotic process#GO:0043065;macromolecule metabolic process#GO:0043170;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;cell death#GO:0008219;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;protein metabolic process#GO:0019538;proteolysis#GO:0006508 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000010645.1|UniProtKB=W5MXD2 W5MXD2 PTHR10099:SF1 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 De novo purine biosynthesis#P02738>Phosphoribosylformylglycinamide synthase#P02898 LEPOC|Ensembl=ENSLOCG00000008810.1|UniProtKB=W5MQR4 W5MQR4 PTHR45742:SF1 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C8 ALPHA CHAIN positive regulation of immune response#GO:0050778;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;humoral immune response#GO:0006959;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;complement activation#GO:0006956;activation of immune response#GO:0002253;immune response#GO:0006955;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of immune response#GO:0050776;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789 extracellular region#GO:0005576;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 complement component#PC00078 LEPOC|Ensembl=ENSLOCG00000008307.1|UniProtKB=W5MNY5 W5MNY5 PTHR14336:SF4 TANDEM PH DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 1 ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of cell communication#GO:0010648;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000004828.1|UniProtKB=W5MBQ8 W5MBQ8 PTHR24012:SF717 RNA BINDING PROTEIN U4_U6 SNRNA-ASSOCIATED-SPLICING FACTOR PRP24 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007072.1|UniProtKB=W5MJK5 W5MJK5 PTHR10612:SF63 APOLIPOPROTEIN D APOLIPOPROTEIN D response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;response to oxygen-containing compound#GO:1901700;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000009873.1|UniProtKB=W5MUL3 W5MUL3 PTHR11686:SF19 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 5 PROENZYME catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 icosanoid metabolic process#GO:0006690;lipid biosynthetic process#GO:0008610;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;response to stress#GO:0006950;cellular process#GO:0009987;sulfur compound catabolic process#GO:0044273;defense response#GO:0006952;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;response to stimulus#GO:0050896;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;glutathione metabolic process#GO:0006749;oxoacid metabolic process#GO:0043436;inflammatory response#GO:0006954 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012742.1|UniProtKB=W5N4X4 W5N4X4 PTHR21082:SF4 PROTEIN INTURNED PROTEIN INTURNED cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003629.1|UniProtKB=W5M7F2 W5M7F2 PTHR15832:SF3 SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG SH2 DOMAIN-CONTAINING PROTEIN 5 postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;postsynaptic density#GO:0014069;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012768.1|UniProtKB=W5N500 W5N500 PTHR14340:SF2 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 MICROFIBRILLAR-ASSOCIATED PROTEIN 3-LIKE LEPOC|Ensembl=ENSLOCG00000005937.1|UniProtKB=W5MFL0 W5MFL0 PTHR43804:SF1 LD18447P PEPTIDE CHAIN RELEASE FACTOR 1, MITOCHONDRIAL primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;translational termination#GO:0006415;translation#GO:0006412;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 translation factor#PC00223;translational protein#PC00263;translation release factor#PC00225 LEPOC|Ensembl=ENSLOCG00000001129.1|UniProtKB=W5LYS3 W5LYS3 PTHR24418:SF369 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ZAP-70 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 T cell activation#P00053>ZAP-70#P01308 LEPOC|Ensembl=ENSLOCG00000007202.1|UniProtKB=W5MK08 W5MK08 PTHR44111:SF2 ELONGATOR COMPLEX PROTEIN 2 ELONGATOR COMPLEX PROTEIN 2 intracellular protein-containing complex#GO:0140535;elongator holoenzyme complex#GO:0033588;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000014901.1|UniProtKB=W5NCJ1 W5NCJ1 PTHR23036:SF172 CYTOKINE RECEPTOR CYTOKINE RECEPTOR COMMON SUBUNIT GAMMA transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;coreceptor activity#GO:0015026;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375 cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;cytokine-mediated signaling pathway#GO:0019221;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;interleukin-2-mediated signaling pathway#GO:0038110;leukocyte activation#GO:0045321;regulation of cellular process#GO:0050794;developmental process#GO:0032502;cellular developmental process#GO:0048869;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;immune system process#GO:0002376;response to peptide#GO:1901652;mononuclear cell differentiation#GO:1903131;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;leukocyte differentiation#GO:0002521;cell development#GO:0048468;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;interleukin-7-mediated signaling pathway#GO:0038111;cellular process#GO:0009987;signal transduction#GO:0007165;interleukin-15-mediated signaling pathway#GO:0035723;interleukin-9-mediated signaling pathway#GO:0038113;response to cytokine#GO:0034097;response to chemical#GO:0042221;lymphocyte activation#GO:0046649 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014548.1|UniProtKB=W5NBA0 W5NBA0 PTHR12722:SF0 XAP-5 PROTEIN-RELATED PROTEIN FAM50A chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008605.1|UniProtKB=W5MQ05 W5MQ05 PTHR14167:SF48 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING PROTEIN 19 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008758.1|UniProtKB=W5MQJ8 W5MQJ8 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007634.1|UniProtKB=W5MLK6 W5MLK6 PTHR23255:SF22 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1B transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;molecular transducer activity#GO:0060089;kinase activity#GO:0016301;activin binding#GO:0048185;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675 animal gross anatomical part developmental process#GO:0160108;activin receptor signaling pathway#GO:0032924;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;signaling#GO:0023052;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;nervous system development#GO:0007399;biological regulation#GO:0065007 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;signaling receptor complex#GO:0043235;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Gonadotropin-releasing hormone receptor pathway#P06664>Alk4#P06845;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283 LEPOC|Ensembl=ENSLOCG00000006702.1|UniProtKB=W5MI87 W5MI87 PTHR23255:SF96 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1 ISOFORM X1 molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein binding#GO:0005515;kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;transferase activity#GO:0016740;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regionalization#GO:0003002;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular developmental process#GO:0048869;dorsal/ventral pattern formation#GO:0009953;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;cellular response to transforming growth factor beta stimulus#GO:0071560;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;response to transforming growth factor beta#GO:0071559;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;cell differentiation#GO:0030154;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363 signaling receptor complex#GO:0043235;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283 LEPOC|Ensembl=ENSLOCG00000005085.1|UniProtKB=W5MCL4 W5MCL4 PTHR11820:SF7 ACYLPYRUVASE OXALOACETATE TAUTOMERASE FAHD1, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001475.1|UniProtKB=W5LZY8 W5LZY8 PTHR10878:SF22 SEGMENT POLARITY PROTEIN DISHEVELLED DIXIN signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013565.1|UniProtKB=W5N7X2 W5N7X2 PTHR11675:SF68 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 7 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000002287.1|UniProtKB=W5M2W0 W5M2W0 PTHR10194:SF4 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 4-RELATED GTPase-activating protein#PC00257 FGF signaling pathway#P00021>RasGAP#P00646;PDGF signaling pathway#P00047>RasGAP#P01152;EGF receptor signaling pathway#P00018>GAP#P00546 LEPOC|Ensembl=ENSLOCG00000014640.1|UniProtKB=W5NBL6 W5NBL6 PTHR23281:SF26 MERLIN/MOESIN/EZRIN/RADIXIN MOESIN protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of anatomical structure morphogenesis#GO:0022603;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;adherens junction#GO:0005912;cell junction#GO:0030054;membraneless organelle#GO:0043228;actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000014832.1|UniProtKB=W5NCB7 W5NCB7 PTHR44998:SF1 FAMILY NOT NAMED UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 LEPOC|Ensembl=ENSLOCG00000003351.1|UniProtKB=W5M6E6 W5M6E6 PTHR10252:SF79 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DNA POLYMERASE EPSILON SUBUNIT 4 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;epsilon DNA polymerase complex#GO:0008622;membraneless organelle#GO:0043228;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011697.1|UniProtKB=W5N168 W5N168 PTHR23254:SF16 EIF4G DOMAIN PROTEIN CBP80_20-DEPENDENT TRANSLATION INITIATION FACTOR translation regulator activity#GO:0045182 regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011169.1|UniProtKB=W5MZB4 W5MZB4 PTHR31570:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1 spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;centrosome cycle#GO:0007098;cell cycle process#GO:0022402 microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010048.1|UniProtKB=W5MV84 W5MV84 PTHR12372:SF6 PECANEX PECANEX-LIKE PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000005328.1|UniProtKB=W5MDF9 W5MDF9 PTHR15741:SF40 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MLX-INTERACTING PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009436.1|UniProtKB=W5MT22 W5MT22 PTHR31859:SF3 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39A LEPOC|Ensembl=ENSLOCG00000014491.1|UniProtKB=W5NB23 W5NB23 PTHR10969:SF55 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GABA(A) RECEPTOR ASSOCIATED PROTEIN ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389;GABA receptor binding#GO:0050811;phospholipid binding#GO:0005543;protein binding#GO:0005515;lipid binding#GO:0008289;binding#GO:0005488;signaling receptor binding#GO:0005102;enzyme binding#GO:0019899 cellular response to stress#GO:0033554;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to nutrient levels#GO:0031669;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;cellular component assembly#GO:0022607 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;autophagosome#GO:0005776;intracellular organelle#GO:0043229;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;bounding membrane of organelle#GO:0098588 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008403.1|UniProtKB=W5MPA7 W5MPA7 PTHR12241:SF147 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL7 catalytic activity, acting on a protein#GO:0140096;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000006422.1|UniProtKB=W5MHA1 W5MHA1 PTHR24369:SF239 ANTIGEN BSP, PUTATIVE-RELATED RETICULON 4 RECEPTOR LIKE 1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009230.1|UniProtKB=W5MSA7 W5MSA7 PTHR11200:SF311 INOSITOL 5-PHOSPHATASE SYNAPTOJANIN-1 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle endocytosis#GO:0048488;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;cellular localization#GO:0051641;import into cell#GO:0098657;transport#GO:0006810;synaptic vesicle cycle#GO:0099504 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 Huntington disease#P00029>Synaptojanin#P00804 LEPOC|Ensembl=ENSLOCG00000016419.1|UniProtKB=W5NI18 W5NI18 PTHR22950:SF184 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID SYMPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;transport#GO:0006810;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;localization#GO:0051179;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;amino acid transporter#PC00046 LEPOC|Ensembl=ENSLOCG00000008582.1|UniProtKB=W5MPX9 W5MPX9 PTHR23291:SF16 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 1 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of extrinsic apoptotic signaling pathway#GO:2001236;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;response to unfolded protein#GO:0006986;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;negative regulation of neuron apoptotic process#GO:0043524;regulation of apoptotic process#GO:0042981 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;ion channel#PC00133 Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 LEPOC|Ensembl=ENSLOCG00000016297.1|UniProtKB=W5NHK8 W5NHK8 PTHR48099:SF32 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED MONOFUNCTIONAL C1-TETRAHYDROFOLATE SYNTHASE, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017706.1|UniProtKB=W5NMF2 W5NMF2 PTHR12871:SF5 BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE II ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000006192.1|UniProtKB=W5MGL3 W5MGL3 PTHR24023:SF539 COLLAGEN ALPHA COLLAGEN TYPE V ALPHA 2 CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 supramolecular complex#GO:0099080;interstitial matrix#GO:0005614;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000001688.1|UniProtKB=W5M0N3 W5M0N3 PTHR23097:SF116 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6B transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011597.1|UniProtKB=W5N0U2 W5N0U2 PTHR15592:SF2 MATRIN 3/NUCLEAR PROTEIN 220-RELATED MATRIN-3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000017757.1|UniProtKB=W5NMK2 W5NMK2 PTHR17068:SF5 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER-LIKE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000003120.1|UniProtKB=W5M5M1 W5M5M1 PTHR10505:SF19 CALCITONIN-RELATED CALCITONIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000013528.1|UniProtKB=W5N7S3 W5N7S3 PTHR10745:SF8 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 DNA POLYMERASE SUBUNIT GAMMA-2 ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;enzyme activator activity#GO:0008047;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;catalytic activity, acting on RNA#GO:0140098;molecular function activator activity#GO:0140677;catalytic activity, acting on a tRNA#GO:0140101;enzyme regulator activity#GO:0030234 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial DNA metabolic process#GO:0032042;DNA-templated DNA replication#GO:0006261;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000009887.1|UniProtKB=W5MUN2 W5MUN2 PTHR16254:SF14 POTASSIUM/PROTON ANTIPORTER-RELATED SOLUTE CARRIER FAMILY 9 MEMBER D1 LEPOC|Ensembl=ENSLOCG00000002594.1|UniProtKB=W5M3T9 W5M3T9 PTHR45733:SF8 FORMIN-J FORMIN-J LEPOC|Ensembl=ENSLOCG00000001607.1|UniProtKB=W5M0E7 W5M0E7 PTHR19134:SF553 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Axon guidance mediated by Slit/Robo#P00008>Ptp10D#P00343 LEPOC|Ensembl=ENSLOCG00000007434.1|UniProtKB=W5MKV7 W5MKV7 PTHR23320:SF130 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED TRANSMEMBRANE PROTEIN 212 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003176.1|UniProtKB=W5M5U4 W5M5U4 PTHR31994:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 42 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 42 LEPOC|Ensembl=ENSLOCG00000016157.1|UniProtKB=W5NH01 W5NH01 PTHR15933:SF13 PROTEIN CBG16327 F-BOX ONLY PROTEIN 30 LEPOC|Ensembl=ENSLOCG00000006348.1|UniProtKB=W5MH05 W5MH05 PTHR45659:SF1 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-C6 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000001463.1|UniProtKB=W5LZW6 W5LZW6 PTHR45640:SF27 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-2 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to heat#GO:0009408;response to stress#GO:0006950;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein refolding#GO:0042026;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein folding#GO:0006457;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 LEPOC|Ensembl=ENSLOCG00000008270.1|UniProtKB=W5MNS8 W5MNS8 PTHR46749:SF1 COMPLEX III ASSEMBLY FACTOR LYRM7 COMPLEX III ASSEMBLY FACTOR LYRM7 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016861.1|UniProtKB=W5NJP3 W5NJP3 PTHR19143:SF199 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-2 kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;receptor tyrosine kinase binding#GO:0030971 multicellular organismal process#GO:0032501;tube development#GO:0035295;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;response to stimulus#GO:0050896;signaling#GO:0023052;blood vessel morphogenesis#GO:0048514;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Angiogenesis#P00005>Ang-2#P00246 LEPOC|Ensembl=ENSLOCG00000017568.1|UniProtKB=W5NM14 W5NM14 PTHR21461:SF52 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000015026.1|UniProtKB=W5NCY8 W5NCY8 PTHR11599:SF13 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-4 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;proteasome complex#GO:0000502;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000006131.1|UniProtKB=W5MG99 W5MG99 PTHR47189:SF1 MHC CLASS II TRANSACTIVATOR MHC CLASS II TRANSACTIVATOR regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 LEPOC|Ensembl=ENSLOCG00000017920.1|UniProtKB=W5NN14 W5NN14 PTHR24228:SF9 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR C-X-C CHEMOKINE RECEPTOR GPR25 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009950.1|UniProtKB=W5MUV8 W5MUV8 PTHR14731:SF0 BRAIN AND ACUTE LEUKEMIA CYTOPLASMIC PROTEIN BRAIN AND ACUTE LEUKEMIA CYTOPLASMIC PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009265.1|UniProtKB=W5MSE1 W5MSE1 PTHR24103:SF609 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM13 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of metabolic process#GO:0019222;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;defense response#GO:0006952;regulation of catabolic process#GO:0009894;response to external stimulus#GO:0009605;innate immune response#GO:0045087;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular process#GO:0009987;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;response to biotic stimulus#GO:0009607;proteasomal protein catabolic process#GO:0010498;defense response to other organism#GO:0098542;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of macroautophagy#GO:0016241;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;positive regulation of macroautophagy#GO:0016239;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013365.1|UniProtKB=W5N764 W5N764 PTHR12373:SF0 ENHANCER OF RUDIMENTARY ERH ENHANCER OF RUDIMENTARY HOMOLOG molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of chromatin organization#GO:1902275;nuclear mRNA surveillance#GO:0071028;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA 3'-end processing#GO:0031123;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016118.1|UniProtKB=W5NGV6 W5NGV6 PTHR23257:SF731 SERINE-THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002128.1|UniProtKB=W5M272 W5M272 PTHR11576:SF16 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 structural molecule activity#GO:0005198;protein binding#GO:0005515;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;binding#GO:0005488 oogenesis#GO:0048477;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;single fertilization#GO:0007338;cell-cell recognition#GO:0009988;cellular developmental process#GO:0048869;developmental process#GO:0032502;sperm-egg recognition#GO:0035036;cellular process involved in reproduction in multicellular organism#GO:0022412;fertilization#GO:0009566;reproductive process#GO:0022414;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;germ cell development#GO:0007281;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;binding of sperm to zona pellucida#GO:0007339;anatomical structure development#GO:0048856;cell recognition#GO:0008037;sexual reproduction#GO:0019953 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013591.1|UniProtKB=W5N802 W5N802 PTHR47050:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 24 TETRATRICOPEPTIDE REPEAT PROTEIN 24 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000014858.1|UniProtKB=W5NCD4 W5NCD4 PTHR23091:SF4 N-TERMINAL ACETYLTRANSFERASE N-TERMINAL AMINO-ACID N(ALPHA)-ACETYLTRANSFERASE NATA acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein acetyltransferase complex#GO:0031248;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000015944.1|UniProtKB=W5NG71 W5NG71 PTHR11705:SF71 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A2 metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000013689.1|UniProtKB=W5N8B6 W5N8B6 PTHR10825:SF31 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 2 chromatin binding#GO:0003682;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;transferase complex#GO:1990234;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000014587.1|UniProtKB=W5NBE1 W5NBE1 PTHR12547:SF130 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730;protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006551.1|UniProtKB=W5MHQ6 W5MHQ6 PTHR24006:SF905 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014402.1|UniProtKB=W5NAS0 W5NAS0 PTHR24083:SF45 NUCLEAR HORMONE RECEPTOR COUP TRANSCRIPTION FACTOR 2 sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;lipid binding#GO:0008289;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;carboxylic acid binding#GO:0031406;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;organic acid binding#GO:0043177;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676 negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000003052.1|UniProtKB=W5M5D7 W5M5D7 PTHR42714:SF9 TRNA MODIFICATION GTPASE GTPBP3 5-TAURINOMETHYLURIDINE-[TRNA] SYNTHASE SUBUNIT GTPB3, MITOCHONDRIAL tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA methylation#GO:0030488;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000009565.1|UniProtKB=W5MTI3 W5MTI3 PTHR10340:SF34 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingolipid catabolic process#GO:0030149;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;phospholipid metabolic process#GO:0006644;organophosphate catabolic process#GO:0046434;ceramide metabolic process#GO:0006672 lysosome#GO:0005764;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015253.1|UniProtKB=W5NDR0 W5NDR0 PTHR11932:SF66 CULLIN CULLIN-4B protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;structural molecule activity#GO:0005198;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899;protein complex scaffold activity#GO:0140378 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;ribosome biogenesis#GO:0042254;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;response to stimulus#GO:0050896;catabolic process#GO:0009056;ribonucleoprotein complex biogenesis#GO:0022613 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000002915.1|UniProtKB=W5M4X3 W5M4X3 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009954.1|UniProtKB=W5MUW9 W5MUW9 PTHR12544:SF49 GLUTAMINASE GLUTAMINASE KIDNEY ISOFORM, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012757.1|UniProtKB=W5N505 W5N505 PTHR11629:SF90 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE SUBUNIT A monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;binding#GO:0005488;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078 protein-containing complex disassembly#GO:0032984;homeostatic process#GO:0042592;catabolic process#GO:0009056;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;macroautophagy#GO:0016236;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;autophagosome maturation#GO:0097352;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;monoatomic ion transport#GO:0006811;process utilizing autophagic mechanism#GO:0061919;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;cellular component disassembly#GO:0022411;monoatomic cation transmembrane transport#GO:0098655;autophagy#GO:0006914;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;metabolic process#GO:0008152 catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000017282.1|UniProtKB=W5NL69 W5NL69 PTHR48017:SF206 OS05G0424000 PROTEIN-RELATED VESICULAR INHIBITORY AMINO ACID TRANSPORTER glycine transmembrane transporter activity#GO:0015187;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171 neutral amino acid transport#GO:0015804;cellular localization#GO:0051641;localization#GO:0051179;glycine transport#GO:0015816;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;synaptic vesicle cycle#GO:0099504 synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;neuron projection terminus#GO:0044306;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;dendritic tree#GO:0097447;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;somatodendritic compartment#GO:0036477;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000014643.1|UniProtKB=W5NBL8 W5NBL8 PTHR23280:SF5 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN 5 positive regulation of cell adhesion#GO:0045785;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell-cell junction#GO:0005911 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000002157.1|UniProtKB=W5M2A5 W5M2A5 PTHR15193:SF2 CD83 ANTIGEN IG-LIKE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011264.1|UniProtKB=W5MZN8 W5MZN8 PTHR24412:SF75 KELCH PROTEIN KELCH-LIKE PROTEIN 1 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015915.1|UniProtKB=W5NG36 W5NG36 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010846.1|UniProtKB=W5MY32 W5MY32 PTHR24338:SF10 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of gene expression#GO:0010468;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000018280.1|UniProtKB=W5NP22 W5NP22 PTHR31815:SF3 AGAP005329-PA TRANSMEMBRANE PROTEIN 200B LEPOC|Ensembl=ENSLOCG00000011009.1|UniProtKB=W5MYQ0 W5MYQ0 PTHR43766:SF5 TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;translation#GO:0006412;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000008982.1|UniProtKB=W5MRD7 W5MRD7 PTHR12263:SF2 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT E 2 monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting two-sector ATPase complex#GO:0016469;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796 ATP synthase#PC00002;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000001299.1|UniProtKB=W5LZB5 W5LZB5 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006747.1|UniProtKB=W5MIF2 W5MIF2 PTHR11453:SF37 ANION EXCHANGE PROTEIN ELECTRONEUTRAL SODIUM BICARBONATE EXCHANGER 1 monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108 cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;biological regulation#GO:0065007;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000005134.1|UniProtKB=W5MCS4 W5MCS4 PTHR10829:SF9 CORTACTIN AND DREBRIN ADF-H DOMAIN-CONTAINING PROTEIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488 cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;regulation of anatomical structure size#GO:0090066;nervous system development#GO:0007399;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;neuron development#GO:0048666;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;system development#GO:0048731;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;synapse organization#GO:0050808;postsynapse organization#GO:0099173;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of supramolecular fiber organization#GO:1902903 cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cell periphery#GO:0071944;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003053.1|UniProtKB=W5M5F0 W5M5F0 PTHR22901:SF0 SIALATE O-ACETYLESTERASE SIALATE O-ACETYLESTERASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 carbohydrate metabolic process#GO:0005975;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 hydrolase#PC00121;esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000014388.1|UniProtKB=W5NAQ5 W5NAQ5 PTHR45888:SF14 HL01030P-RELATED ZINC FINGER PROTEIN NEURO-D4 transcription coregulator activity#GO:0003712;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001677.1|UniProtKB=W5M0M4 W5M0M4 PTHR45909:SF1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular transport#GO:0046907;protein localization to cell periphery#GO:1990778;protein localization to Golgi apparatus#GO:0034067;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;protein localization to organelle#GO:0033365;Golgi to plasma membrane transport#GO:0006893;Golgi to plasma membrane protein transport#GO:0043001 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000006602.1|UniProtKB=W5MHW7 W5MHW7 PTHR11347:SF34 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1A catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585 cell body#GO:0044297;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185;hydrolase#PC00121 CCKR signaling map#P06959>PDE#P07161 LEPOC|Ensembl=ENSLOCG00000012170.1|UniProtKB=W5N2V9 W5N2V9 PTHR12223:SF36 VESICULAR MANNOSE-BINDING LECTIN VESICULAR INTEGRAL-MEMBRANE PROTEIN VIP36 carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029;small molecule binding#GO:0036094;binding#GO:0005488 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004964.1|UniProtKB=W5MC61 W5MC61 PTHR16219:SF3 AUGMIN SUBUNIT 4 FAMILY MEMBER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 4 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694 microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006789.1|UniProtKB=W5MIJ4 W5MIJ4 PTHR16295:SF17 TRAF-TYPE ZINC FINGER PROTEIN-RELATED XIAP-ASSOCIATED FACTOR 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016351.1|UniProtKB=W5NHU0 W5NHU0 PTHR24351:SF182 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Apoptosis signaling pathway#P00006>PKCs#P00318;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Endothelin signaling pathway#P00019>PKC#P00568;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Angiogenesis#P00005>PKC#P00219;VEGF signaling pathway#P00056>PKC#P01425 LEPOC|Ensembl=ENSLOCG00000007562.1|UniProtKB=W5MLB8 W5MLB8 PTHR10865:SF22 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 3 binding#GO:0005488;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;protein binding#GO:0005515 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000001366.1|UniProtKB=W5LZJ6 W5LZJ6 PTHR24204:SF7 INSULIN GENE ENHANCER PROTEIN LIM ZINC-BINDING DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;axonogenesis#GO:0007409;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell fate specification#GO:0001708;positive regulation of transcription by RNA polymerase II#GO:0045944;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;neuron fate commitment#GO:0048663;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000008434.1|UniProtKB=W5MPG5 W5MPG5 PTHR21068:SF55 SPARTIN SPARTIN negative regulation of BMP signaling pathway#GO:0030514;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell division#GO:0051301;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000005371.1|UniProtKB=W5MDL9 W5MDL9 PTHR24271:SF101 KALLIKREIN-RELATED MAST CELL PROTEASE 4 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000010488.1|UniProtKB=W5MWV3 W5MWV3 PTHR10177:SF193 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B1 enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic metaphase chromosome alignment#GO:0007080;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;organelle fission#GO:0048285;localization#GO:0051179;nuclear division#GO:0000280;organelle localization#GO:0051640;mitotic cell cycle phase transition#GO:0044772;chromosome localization#GO:0050000;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;G1/S transition of mitotic cell cycle#GO:0000082;metaphase chromosome alignment#GO:0051310 intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;mitochondrial matrix#GO:0005759;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;protein kinase complex#GO:1902911;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 kinase activator#PC00138 p53 pathway#P00059>Cyclin B#P04614;Cell cycle#P00013>Cyclin B#P00486 LEPOC|Ensembl=ENSLOCG00000013131.1|UniProtKB=W5N6C0 W5N6C0 PTHR19960:SF30 TEKTIN TEKTIN cell projection organization#GO:0030030;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;organelle assembly#GO:0070925;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031 microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000012081.1|UniProtKB=W5N2K4 W5N2K4 PTHR13355:SF11 GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;glucosamine 6-phosphate N-acetyltransferase activity#GO:0004343;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011981.1|UniProtKB=W5N276 W5N276 PTHR23089:SF18 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000004520.1|UniProtKB=W5MAK2 W5MAK2 EIF3M PTHR15350:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;translation#GO:0006412;translational initiation#GO:0006413 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;eukaryotic translation initiation factor 3 complex#GO:0005852 LEPOC|Ensembl=ENSLOCG00000014150.1|UniProtKB=W5N9X2 W5N9X2 PTHR15327:SF0 MICROFIBRIL-ASSOCIATED PROTEIN MICROFIBRILLAR-ASSOCIATED PROTEIN 1 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000014985.1|UniProtKB=W5NCV1 W5NCV1 PTHR24416:SF131 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 1 kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;fibroblast growth factor binding#GO:0017134;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of developmental process#GO:0051094;response to fibroblast growth factor#GO:0071774;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636;Angiogenesis#P00005>FGFR-1#P00186 LEPOC|Ensembl=ENSLOCG00000000970.1|UniProtKB=W5LYA0 W5LYA0 PTHR45615:SF1 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-7 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146 muscle system process#GO:0003012;heart process#GO:0003015;circulatory system development#GO:0072359;actin-mediated cell contraction#GO:0070252;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;animal gross anatomical part developmental process#GO:0160108;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;system development#GO:0048731;cellular process#GO:0009987;actin filament-based movement#GO:0030048;heart development#GO:0007507;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;muscle contraction#GO:0006936;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;heart contraction#GO:0060047;system process#GO:0003008 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867 LEPOC|Ensembl=ENSLOCG00000006656.1|UniProtKB=W5MI29 W5MI29 PTHR45973:SF38 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN AXONEMAL ASSEMBLY FACTOR 1 protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component organization#GO:0016043;cilium assembly#GO:0060271;determination of left/right symmetry#GO:0007368;cell projection organization#GO:0030030;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;pattern specification process#GO:0007389;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;cilium organization#GO:0044782;axoneme assembly#GO:0035082;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;multicellular organismal process#GO:0032501;regionalization#GO:0003002;cellular component assembly#GO:0022607;determination of bilateral symmetry#GO:0009855;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;left/right pattern formation#GO:0060972;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007267.1|UniProtKB=W5MK86 W5MK86 PTHR15856:SF26 PHD FINGER PROTEIN 20-RELATED PHD FINGER PROTEIN 20-LIKE PROTEIN 1 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;chromatin#GO:0000785;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000012755.1|UniProtKB=W5N4Y7 W5N4Y7 PTHR21561:SF12 INO80 COMPLEX SUBUNIT B INO80 COMPLEX SUBUNIT B intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;Ino80 complex#GO:0031011;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000004625.1|UniProtKB=W5MB54 W5MB54 PTHR24023:SF1139 COLLAGEN ALPHA COLLAGEN TYPE V ALPHA 1 CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000006316.1|UniProtKB=W5MGY1 W5MGY1 PTHR45874:SF2 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-C10 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000012433.1|UniProtKB=W5N3V4 W5N3V4 PTHR45700:SF2 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3C acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000005871.1|UniProtKB=W5MFD0 W5MFD0 PTHR10131:SF164 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;signal transduction#GO:0007165;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006697.1|UniProtKB=W5MI81 W5MI81 PTHR44340:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 10 ENDOPLASMIC RETICULUM DISULFIDE REDUCTASE DNAJC10 binding#GO:0005488;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;protein-disulfide reductase activity#GO:0015035;protein binding#GO:0005515;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000014151.1|UniProtKB=W5N9X6 W5N9X6 PTHR23122:SF14 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PROTEIN PALS1 developmental process#GO:0032502;protein localization to cell periphery#GO:1990778;neurogenesis#GO:0022008;morphogenesis of an epithelium#GO:0002009;intracellular protein localization#GO:0008104;cellular developmental process#GO:0048869;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;cellular process#GO:0009987;macromolecule localization#GO:0033036;nervous system development#GO:0007399;embryo development#GO:0009790;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelium development#GO:0060429;establishment or maintenance of bipolar cell polarity#GO:0061245;generation of neurons#GO:0048699;localization within membrane#GO:0051668;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of cell polarity#GO:0007163;system development#GO:0048731;anatomical structure development#GO:0048856;cellular localization#GO:0051641;localization#GO:0051179;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;tissue morphogenesis#GO:0048729;anatomical structure morphogenesis#GO:0009653;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;cell differentiation#GO:0030154 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014310.1|UniProtKB=W5NAH5 W5NAH5 PTHR23113:SF193 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of synaptic plasticity#GO:0048167;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of trans-synaptic signaling#GO:0099177;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;regulation of signaling#GO:0023051;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000012498.1|UniProtKB=W5N425 W5N425 PTHR45803:SF1 SOX100B TRANSCRIPTION FACTOR SOX-9 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;skeletal system development#GO:0001501;negative regulation of DNA-templated transcription#GO:0045892;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;negative regulation of RNA metabolic process#GO:0051253;positive regulation of cell differentiation#GO:0045597;negative regulation of RNA biosynthetic process#GO:1902679;gliogenesis#GO:0042063;morphogenesis of an epithelium#GO:0002009;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;heart development#GO:0007507;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;cartilage development#GO:0051216;regulation of RNA metabolic process#GO:0051252;tissue morphogenesis#GO:0048729;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;connective tissue development#GO:0061448;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;tissue development#GO:0009888;glial cell differentiation#GO:0010001;chondrocyte differentiation#GO:0002062;oligodendrocyte differentiation#GO:0048709 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000001561.1|UniProtKB=W5M078 W5M078 PTHR13192:SF3 MY011 PROTEIN COBALAMIN TRAFFICKING PROTEIN CBLD cellular process#GO:0009987;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002498.1|UniProtKB=W5M3H2 W5M3H2 PTHR32289:SF4 PROTEIN FAM167A PROTEIN FAM167B LEPOC|Ensembl=ENSLOCG00000007526.1|UniProtKB=W5ML70 W5ML70 PTHR31601:SF2 28S RIBOSOMAL PROTEIN S36, MITOCHONDRIAL ALPHA-KETOGLUTARATE DEHYDROGENASE COMPONENT 4 cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 catalytic complex#GO:1902494;transferase complex#GO:1990234;oxidoreductase complex#GO:1990204;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000006354.1|UniProtKB=W5MH13 W5MH13 PTHR45746:SF3 LP21163P REGULATOR OF G PROTEIN SIGNALING 11 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 LEPOC|Ensembl=ENSLOCG00000012331.1|UniProtKB=W5N3H7 W5N3H7 PTHR13723:SF189 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 12 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000006477.1|UniProtKB=W5MHG7 W5MHG7 PTHR24251:SF60 OVOCHYMASE-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000001644.1|UniProtKB=W5M0J3 W5M0J3 PTHR31333:SF6 PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3 FAMILY MEMBER MUM1 LIKE 1 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008226.1|UniProtKB=W5MNM9 W5MNM9 PTHR43243:SF108 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;amino acid transporter#PC00046 LEPOC|Ensembl=ENSLOCG00000007171.1|UniProtKB=W5MJW5 W5MJW5 PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN SENTAN calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000014727.1|UniProtKB=W5NBX3 W5NBX3 PTHR16188:SF4 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14A enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;protein serine/threonine phosphatase inhibitor activity#GO:0004865;phosphatase regulator activity#GO:0019208;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000014496.1|UniProtKB=W5NB32 W5NB32 PTHR20937:SF18 IP14615P BHLH TRANSCRIPTION FACTOR MESP-B-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;mesoderm formation#GO:0001707;regionalization#GO:0003002;tissue development#GO:0009888;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;heart morphogenesis#GO:0003007;mesoderm morphogenesis#GO:0048332;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;tissue morphogenesis#GO:0048729;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;embryonic pattern specification#GO:0009880;heart development#GO:0007507;embryo development#GO:0009790;anterior/posterior pattern specification#GO:0009952;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;mesoderm development#GO:0007498;anterior/posterior axis specification#GO:0009948;anatomical structure formation involved in morphogenesis#GO:0048646;gastrulation#GO:0007369;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;formation of primary germ layer#GO:0001704 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000000553.1|UniProtKB=W5LWV3 W5LWV3 PTHR18962:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 39 COILED-COIL DOMAIN-CONTAINING PROTEIN 39 cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285;inner dynein arm assembly#GO:0036159;cilium or flagellum-dependent cell motility#GO:0001539;microtubule-based transport#GO:0099111;cilium movement#GO:0003341;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;left/right pattern formation#GO:0060972;cytoskeleton organization#GO:0007010;determination of bilateral symmetry#GO:0009855;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;axoneme assembly#GO:0035082;localization#GO:0051179;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;pattern specification process#GO:0007389;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;organelle assembly#GO:0070925;cell motility#GO:0048870;microtubule-based movement#GO:0007018;determination of left/right symmetry#GO:0007368;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;specification of symmetry#GO:0009799;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;regionalization#GO:0003002 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000015294.1|UniProtKB=W5NDV7 W5NDV7 PTHR19282:SF169 TETRASPANIN TETRASPANIN-6 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003772.1|UniProtKB=W5M7Y8 W5M7Y8 PTHR11818:SF119 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN A structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;sensory system development#GO:0048880;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory organ development#GO:0007423;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000000200.1|UniProtKB=W5LVR6 W5LVR6 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014666.1|UniProtKB=W5NBP1 W5NBP1 PTHR34648:SF7 CLOCK-INTERACTING PACEMAKER SI:CH211-132B12.7 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000001757.1|UniProtKB=W5M0W8 W5M0W8 PTHR24652:SF67 LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2 LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000006546.1|UniProtKB=W5MHQ3 W5MHQ3 PTHR11601:SF65 CYSTEINE DESULFURYLASE FAMILY MEMBER CYSTEINE DESULFURASE sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;mitochondrion#GO:0005739 lyase#PC00144;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003883.1|UniProtKB=W5M8C7 W5M8C7 PTHR43340:SF7 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;magnesium ion binding#GO:0000287;metal ion binding#GO:0046872 primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001270.1|UniProtKB=W5LZ85 W5LZ85 PTHR31547:SF1 MULTIVESICULAR BODY SUBUNIT 12B MULTIVESICULAR BODY SUBUNIT 12B regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;ESCRT I complex#GO:0000813;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000009399.1|UniProtKB=W5MSV9 W5MSV9 PTHR23354:SF69 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED OXIDATION RESISTANCE PROTEIN 1 response to stimulus#GO:0050896;response to oxidative stress#GO:0006979;response to stress#GO:0006950 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003528.1|UniProtKB=W5M713 W5M713 PTHR11774:SF11 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA catalytic activity#GO:0003824;transferase activity#GO:0016740;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096 protein targeting#GO:0006605;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transferase complex#GO:1990234;catalytic complex#GO:1902494 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000003997.1|UniProtKB=A0A075B5H9 A0A075B5H9 PTHR46385:SF3 PAIRED MESODERM HOMEOBOX PROTEIN 1-RELATED PAIRED MESODERM HOMEOBOX PROTEIN 2 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 Gonadotropin-releasing hormone receptor pathway#P06664>Prx2#P06731 LEPOC|Ensembl=ENSLOCG00000000341.1|UniProtKB=W5LW62 W5LW62 PTHR24369:SF102 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;regulation of cell junction assembly#GO:1901888;synapse organization#GO:0050808;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;positive regulation of synapse assembly#GO:0051965;positive regulation of developmental process#GO:0051094;biological regulation#GO:0065007;regulation of synapse assembly#GO:0051963;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;regulation of biological quality#GO:0065008;synaptic membrane adhesion#GO:0099560;regulation of synapse organization#GO:0050807;positive regulation of cellular component organization#GO:0051130;cell adhesion#GO:0007155;regulation of cellular component biogenesis#GO:0044087;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of organelle organization#GO:0033043;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;regulation of multicellular organismal process#GO:0051239;positive regulation of cellular component biogenesis#GO:0044089;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cell-cell adhesion#GO:0098609 postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;cell junction#GO:0030054 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000905.1|UniProtKB=W5LY07 W5LY07 PTHR17608:SF4 GENETIC SUPPRESSOR ELEMENT 1 GENETIC SUPPRESSOR ELEMENT 1 LEPOC|Ensembl=ENSLOCG00000017297.1|UniProtKB=W5NL93 W5NL93 PTHR18860:SF16 14-3-3 PROTEIN 14-3-3 PROTEIN ETA scaffold/adaptor protein#PC00226 FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;Parkinson disease#P00049>14-3-3#P01238 LEPOC|Ensembl=ENSLOCG00000003231.1|UniProtKB=W5M622 W5M622 PTHR13554:SF10 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015866.1|UniProtKB=W5NFX6 W5NFX6 PTHR24188:SF29 ANKYRIN REPEAT PROTEIN GH09064P LEPOC|Ensembl=ENSLOCG00000011837.1|UniProtKB=W5N1Q4 W5N1Q4 PTHR31859:SF23 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39B LEPOC|Ensembl=ENSLOCG00000015976.1|UniProtKB=W5NGD5 W5NGD5 PTHR24115:SF978 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF13B protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 cellular process#GO:0009987;microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018 organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005226.1|UniProtKB=W5MD42 W5MD42 PTHR24027:SF85 CADHERIN-23 CADHERIN-11 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell migration#GO:0016477;cellular component assembly#GO:0022607;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cell junction organization#GO:0034330;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;anatomical structure morphogenesis#GO:0009653 adherens junction#GO:0005912;anchoring junction#GO:0070161;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000001164.1|UniProtKB=W5LYV3 W5LYV3 PTHR15224:SF1 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000016152.1|UniProtKB=W5NGZ5 W5NGZ5 PTHR10472:SF5 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 1 catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;deacylase activity#GO:0160215;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000011322.1|UniProtKB=W5MZV1 W5MZV1 PTHR11101:SF83 PHOSPHATE TRANSPORTER SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 2 active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;phosphate transmembrane transporter activity#GO:0005315;symporter activity#GO:0015293 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;phosphate ion transport#GO:0006817;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001613.1|UniProtKB=W5M0I6 W5M0I6 PTHR12897:SF4 COLON CANCER-ASSOCIATED PROTEIN MIC1 REGULATOR OF MON1-CCZ1 COMPLEX protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 regulation of catabolic process#GO:0009894;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of autophagy#GO:0010506 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;late endosome membrane#GO:0031902;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008 LEPOC|Ensembl=ENSLOCG00000014874.1|UniProtKB=W5NCG0 W5NCG0 PTHR11486:SF71 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 17 fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;response to fibroblast growth factor#GO:0071774;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000001439.1|UniProtKB=W5LZV0 W5LZV0 PTHR10454:SF13 CASPASE CASPASE-4 endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;inflammatory response#GO:0006954;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;positive regulation of defense response#GO:0031349;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;positive regulation of neuron apoptotic process#GO:0043525;regulation of response to stress#GO:0080134;positive regulation of inflammatory response#GO:0050729;defense response#GO:0006952;positive regulation of apoptotic process#GO:0043065;positive regulation of response to external stimulus#GO:0032103 canonical inflammasome complex#GO:0061702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000493.1|UniProtKB=W5LWP0 W5LWP0 PTHR12618:SF20 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000001704.1|UniProtKB=W5M0Q4 W5M0Q4 PTHR12318:SF0 TESTOSTERONE-REGULATED PROTEIN RP2 ACYL-COENZYME A DIPHOSPHATASE NUDT19 LEPOC|Ensembl=ENSLOCG00000012892.1|UniProtKB=W5N5G3 W5N5G3 PTHR24257:SF10 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER ELASTASE-1 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000006127.1|UniProtKB=W5MG95 W5MG95 PTHR11142:SF4 PSEUDOURIDYLATE SYNTHASE PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG catalytic activity, acting on a tRNA#GO:0140101;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;pseudouridine synthesis#GO:0001522;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000016043.1|UniProtKB=W5NGK2 W5NGK2 PTHR24034:SF110 EGF-LIKE DOMAIN-CONTAINING PROTEIN PROTEIN DISULFIDE ISOMERASE CRELD2 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000018304.1|UniProtKB=W5NP46 W5NP46 PTHR31894:SF0 UPF0461 PROTEIN C5ORF24 UPF0461 PROTEIN C5ORF24 LEPOC|Ensembl=ENSLOCG00000011084.1|UniProtKB=W5MZ01 W5MZ01 PTHR11304:SF18 EPHRIN EPHRIN-B2 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;tube development#GO:0035295;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;ephrin receptor signaling pathway#GO:0048013;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666 presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 Angiogenesis#P00005>Eph#P00239 LEPOC|Ensembl=ENSLOCG00000015007.1|UniProtKB=W5NCW7 W5NCW7 PTHR23511:SF34 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2B ISOFORM X1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000004866.1|UniProtKB=W5MBT7 W5MBT7 PTHR22895:SF9 ARMADILLO REPEAT-CONTAINING PROTEIN 6 ARMADILLO REPEAT-CONTAINING PROTEIN 6 anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cell development#GO:0048468;hemopoiesis#GO:0030097;cellular process#GO:0009987;developmental process#GO:0032502 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000013194.1|UniProtKB=W5N6J5 W5N6J5 PTHR11506:SF2 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN MACROSIALIN localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184 membrane#GO:0016020;vesicle membrane#GO:0012506;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;late endosome membrane#GO:0031902;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000005817.1|UniProtKB=W5MF67 W5MF67 PTHR15822:SF28 TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN TYROSYL-DNA PHOSPHODIESTERASE 2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 membraneless organelle#GO:0043228;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000013354.1|UniProtKB=W5N787 W5N787 PTHR10972:SF146 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN cholesterol binding#GO:0015485;steroid binding#GO:0005496;lipid binding#GO:0008289;alcohol binding#GO:0043178;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nuclear envelope#GO:0005635;plasma membrane#GO:0005886;endomembrane system#GO:0012505;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;endoplasmic reticulum#GO:0005783 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000016080.1|UniProtKB=W5NGQ5 W5NGQ5 PTHR13408:SF5 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000015645.1|UniProtKB=W5NF51 W5NF51 PTHR24248:SF130 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2B ADRENERGIC RECEPTOR cation binding#GO:0043169;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;hormone binding#GO:0042562 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000000054.1|UniProtKB=W5LVA7 W5LVA7 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007396.1|UniProtKB=W5MKT0 W5MKT0 PTHR23086:SF54 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 ALPHA kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transferase#PC00220;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000007790.1|UniProtKB=W5MM46 W5MM46 PTHR20932:SF2 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 1-RELATED LEPOC|Ensembl=ENSLOCG00000004112.1|UniProtKB=W5M955 W5M955 PTHR32341:SF21 INTERFERON-INDUCIBLE GTPASE IRG-TYPE G DOMAIN-CONTAINING PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000010347.1|UniProtKB=W5MWB6 W5MWB6 PTHR15444:SF4 SECRETED PHOSPHOPROTEIN 24 SECRETED PHOSPHOPROTEIN 24 LEPOC|Ensembl=ENSLOCG00000005144.1|UniProtKB=W5MCT4 W5MCT4 PTHR12234:SF1 FORMIMINOTRANSFERASE-CYCLODEAMINASE FORMIMINOTRANSFERASE N-TERMINAL SUBDOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740 LEPOC|Ensembl=ENSLOCG00000017305.1|UniProtKB=W5NLA1 W5NLA1 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000001710.1|UniProtKB=W5M0R1 W5M0R1 PTHR14191:SF4 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515 protein localization to plasma membrane#GO:0072659;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000742.1|UniProtKB=W5LXG8 W5LXG8 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000018291.1|UniProtKB=W5NP33 W5NP33 PTHR11984:SF60 CONNEXIN GAP JUNCTION ALPHA-9 PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 regulation of biological process#GO:0050789;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cell communication#GO:0007154 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;anchoring junction#GO:0070161 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000005655.1|UniProtKB=W5MEM5 W5MEM5 PTHR23068:SF53 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5-)-METHYLTRANSFERASE DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA methyltransferase#PC00013 LEPOC|Ensembl=ENSLOCG00000000514.1|UniProtKB=W5LWR0 W5LWR0 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016819.1|UniProtKB=W5NJH8 W5NJH8 PTHR23414:SF2 ADRENOMEDULLIN, ADM PROTEIN ADM2 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;hormone activity#GO:0005179 regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;renal system process#GO:0003014;cellular process#GO:0009987;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of system process#GO:0044057;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of heart contraction#GO:0008016;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;cell communication#GO:0007154;regulation of biological quality#GO:0065008 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000002407.1|UniProtKB=W5M360 W5M360 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003787.1|UniProtKB=W5M808 W5M808 PTHR24124:SF7 ANKYRIN REPEAT FAMILY A NF-KAPPA-B INHIBITOR DELTA biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007026.1|UniProtKB=W5MJF7 W5MJF7 PTHR10333:SF106 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 4 chromatin-protein adaptor activity#GO:0140463;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566 regulation of apoptotic process#GO:0042981;regulation of biosynthetic process#GO:0009889;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008784.1|UniProtKB=W5MQP0 W5MQP0 PTHR23423:SF10 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184C transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016310.1|UniProtKB=W5NHM5 W5NHM5 PTHR10623:SF10 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 3 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 chromosome segregation#GO:0007059;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;microtubule end#GO:1990752;cytoplasmic microtubule#GO:0005881;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000006690.1|UniProtKB=W5MI75 W5MI75 PTHR24056:SF334 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 1 protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096 negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;cellular response to stress#GO:0033554;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;cell cycle G2/M phase transition#GO:0044839;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278;mitotic cell cycle phase transition#GO:0044772;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;mitotic cell cycle process#GO:1903047 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway#P00059>Cdc2#P04634 LEPOC|Ensembl=ENSLOCG00000006599.1|UniProtKB=W5MHW4 W5MHW4 PTHR12178:SF2 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 2 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012751.1|UniProtKB=W5N4X9 W5N4X9 PTHR12560:SF62 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 3 ISOFORM X1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide metabolic process#GO:0006672 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011588.1|UniProtKB=W5N0T1 W5N0T1 PTHR14928:SF6 MICRO-RNA BINDING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7B RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012327.1|UniProtKB=W5N3G0 W5N3G0 PTHR16209:SF3 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 PROLINE-RICH PROTEIN 7 cell communication#GO:0007154;synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052 nucleus#GO:0005634;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;intracellular membraneless organelle#GO:0043232;cell junction#GO:0030054;membraneless organelle#GO:0043228;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004269.1|UniProtKB=W5M9Q1 W5M9Q1 PTHR24351:SF188 RIBOSOMAL PROTEIN S6 KINASE SERINE_THREONINE-PROTEIN KINASE SGK1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013842.1|UniProtKB=W5N8W5 W5N8W5 PTHR46708:SF11 TENASCIN RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ETA signaling receptor binding#GO:0005102;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877 cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;cell-substrate junction assembly#GO:0007044;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;circulatory system development#GO:0072359;cell junction organization#GO:0034330;developmental process#GO:0032502;cell-substrate junction organization#GO:0150115;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;cellular component assembly#GO:0022607;heart development#GO:0007507;multicellular organismal process#GO:0032501 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000004710.1|UniProtKB=W5MB92 W5MB92 PTHR17204:SF25 PRE-MRNA PROCESSING PROTEIN PRP39-RELATED RRM DOMAIN-CONTAINING PROTEIN RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;nucleic acid binding#GO:0003676 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000015361.1|UniProtKB=W5NE43 W5NE43 PTHR45701:SF8 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 5 binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;protein binding#GO:0005515;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484 localization#GO:0051179;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;transport#GO:0006810;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987 protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006733.1|UniProtKB=W5MIC3 W5MIC3 PTHR12612:SF44 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000009804.1|UniProtKB=W5MUC4 W5MUC4 PTHR23287:SF16 RUBY-EYE2-LIKE PROTEIN TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000016825.1|UniProtKB=W5NJI6 W5NJI6 PTHR11783:SF107 SULFOTRANSFERASE SULT SULFOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015869.1|UniProtKB=W5NFY0 W5NFY0 PTHR44027:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5G chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017212.1|UniProtKB=W5NKX1 W5NKX1 PTHR10642:SF35 RIBONUCLEASE H1 RIBONUCLEASE H1 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;DNA-templated DNA replication#GO:0006261;mitochondrial DNA metabolic process#GO:0032042;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;endoribonuclease#PC00094 DNA replication#P00017>RNase H#P00538 LEPOC|Ensembl=ENSLOCG00000007186.1|UniProtKB=W5MJZ2 W5MJZ2 PTHR46914:SF1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 enzyme regulator activity#GO:0030234;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;detection of stimulus#GO:0051606;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;defense response#GO:0006952;response to external stimulus#GO:0009605;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to bacterium#GO:0009617;inflammatory response#GO:0006954;defense response to bacterium#GO:0042742 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;canonical inflammasome complex#GO:0061702;cytosol#GO:0005829 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000012900.1|UniProtKB=W5N5H2 W5N5H2 PTHR15371:SF0 TIM23 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM23 transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542 organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739 amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006581.1|UniProtKB=W5MHT7 W5MHT7 PTHR13603:SF1 TRANSMEMBRANE PROTEIN 186 TRANSMEMBRANE PROTEIN 186 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016996.1|UniProtKB=W5NK50 W5NK50 PTHR24403:SF103 ZINC FINGER PROTEIN E3 SUMO-PROTEIN LIGASE ZNF451 ISOFORM X1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011219.1|UniProtKB=W5MZH4 W5MZH4 PTHR45986:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 2 ZINC FINGER MATRIN-TYPE PROTEIN 2 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;U4/U6 x U5 tri-snRNP complex#GO:0046540;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011881.1|UniProtKB=W5N1U6 W5N1U6 PTHR33802:SF4 SI:CH211-161H7.5-RELATED SI:DKEY-29D8.3 LEPOC|Ensembl=ENSLOCG00000002513.1|UniProtKB=W5M3J6 W5M3J6 PTHR24291:SF5 CYTOCHROME P450 FAMILY 4 1,25-DIHYDROXYVITAMIN D(3) 24-HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491 lipid catabolic process#GO:0016042;cellular process#GO:0009987;response to nutrient levels#GO:0031667;steroid metabolic process#GO:0008202;response to chemical#GO:0042221;response to lipid#GO:0033993;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;vitamin D metabolic process#GO:0042359;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;steroid catabolic process#GO:0006706 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 Vitamin D metabolism and pathway#P04396>24-Hydroxylase#P04608;Vitamin D metabolism and pathway#P04396>24-Hydroxylase#G04688 LEPOC|Ensembl=ENSLOCG00000008442.1|UniProtKB=W5MPF7 W5MPF7 PTHR14917:SF5 SPERMATOGENESIS-ASSOCIATED PROTEIN 7 SPERMATOGENESIS-ASSOCIATED 7 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;homeostatic process#GO:0042592;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;microtubule-based process#GO:0007017;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;microtubule cytoskeleton organization#GO:0000226;retina homeostasis#GO:0001895;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axoneme#GO:0005930;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;9+0 non-motile cilium#GO:0097731;microtubule cytoskeleton#GO:0015630;photoreceptor cell cilium#GO:0097733;neuron projection#GO:0043005;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 LEPOC|Ensembl=ENSLOCG00000001015.1|UniProtKB=W5LYF3 W5LYF3 PTHR11465:SF9 CATALASE CATALASE heme binding#GO:0020037;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;binding#GO:0005488;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;tetrapyrrole binding#GO:0046906 hydrogen peroxide metabolic process#GO:0042743;catabolic process#GO:0009056;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;response to stress#GO:0006950;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;response to oxygen-containing compound#GO:1901700;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;mitochondrion#GO:0005739;peroxisome#GO:0005777 peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000006458.1|UniProtKB=W5MHE3 W5MHE3 PTHR11629:SF21 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 3 protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;enzyme binding#GO:0019899;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 protein-containing complex disassembly#GO:0032984;homeostatic process#GO:0042592;catabolic process#GO:0009056;vacuole organization#GO:0007033;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of intracellular pH#GO:0051453;organelle assembly#GO:0070925;regulation of pH#GO:0006885;biological regulation#GO:0065007;macroautophagy#GO:0016236;monoatomic ion transmembrane transport#GO:0034220;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;autophagosome maturation#GO:0097352;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular component disassembly#GO:0022411;transmembrane transport#GO:0055085;monoatomic cation transmembrane transport#GO:0098655;cellular component assembly#GO:0022607;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;monoatomic ion homeostasis#GO:0050801;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cation-transporting ATPase complex#GO:0090533;apical plasma membrane#GO:0016324;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;apical part of cell#GO:0045177;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000014558.1|UniProtKB=W5NBA8 W5NBA8 PTHR45870:SF11 TUBULIN MONOGLYCYLASE TTLL3 TUBULIN MONOGLYCYLASE TTLL3 ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a protein#GO:0140096;ligase activity#GO:0016874;catalytic activity#GO:0003824 microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cell projection organization#GO:0030030;gamete generation#GO:0007276;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;sperm flagellum#GO:0036126;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000003903.1|UniProtKB=W5M8E8 W5M8E8 PTHR16288:SF0 WD40 REPEAT PROTEIN 4 TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT WDR4 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015764.1|UniProtKB=W5NFJ7 W5NFJ7 PTHR21220:SF0 DNA-DEPENDENT METALLOPROTEASE SPRTN DNA-DEPENDENT METALLOPROTEASE SPRTN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000014172.1|UniProtKB=W5NA17 W5NA17 PTHR10166:SF25 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-3 passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 membrane protein complex#GO:0098796;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010393.1|UniProtKB=W5MWI5 W5MWI5 PTHR44899:SF1 CAMK FAMILY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE NEK5 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000009541.1|UniProtKB=W5MTF2 W5MTF2 PTHR45638:SF19 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL ALPHA-3-LIKE ion channel#PC00133;ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000011865.1|UniProtKB=W5N1T0 W5N1T0 PTHR10656:SF79 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane#GO:0016020;cellular anatomical structure#GO:0110165 nucleotidyltransferase#PC00174;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004816.1|UniProtKB=W5MBN1 W5MBN1 PTHR11037:SF22 TRANSCRIPTION FACTOR CP2 ALPHA-GLOBIN TRANSCRIPTION FACTOR CP2 ISOFORM X3 binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014117.1|UniProtKB=W5N9T2 W5N9T2 PTHR24070:SF252 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE PROTEIN FAMILY MEMBER 12 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;establishment or maintenance of cell polarity#GO:0007163;Ras protein signal transduction#GO:0007265 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000001307.1|UniProtKB=W5LZC9 W5LZC9 PTHR22883:SF49 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC7 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;protein localization to cell periphery#GO:1990778;protein targeting to membrane#GO:0006612;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;localization within membrane#GO:0051668;regulation of signaling#GO:0023051;localization#GO:0051179;cellular localization#GO:0051641;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;protein targeting#GO:0006605 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009240.1|UniProtKB=W5MSB9 W5MSB9 PTHR12480:SF6 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4 sequence-specific DNA binding#GO:0043565;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein-containing complex disassembly#GO:0043244;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein metabolic process#GO:0051247;positive regulation of cellular component organization#GO:0051130;positive regulation of translation#GO:0045727;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016847.1|UniProtKB=W5NJL5 W5NJL5 PTHR45689:SF4 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 4 potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;dendrite#GO:0030425;axon#GO:0030424;dendritic tree#GO:0097447;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000010444.1|UniProtKB=W5MWP5 W5MWP5 PTHR11359:SF1 AMP DEAMINASE AMP DEAMINASE 1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281 deaminase#PC00088 LEPOC|Ensembl=ENSLOCG00000014065.1|UniProtKB=W5N9M2 W5N9M2 PTHR15132:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 2 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 2 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000017454.1|UniProtKB=W5NLQ0 W5NLQ0 PTHR26451:SF847 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004552.1|UniProtKB=W5MAN9 W5MAN9 PTHR13449:SF2 INTEGRAL MEMBRANE PROTEIN GPR177 PROTEIN WNTLESS HOMOLOG binding#GO:0005488;Wnt-protein binding#GO:0017147;protein binding#GO:0005515 protein localization to extracellular region#GO:0071692;regulation of biological process#GO:0050789;signaling#GO:0023052;export from cell#GO:0140352;signal release#GO:0023061;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;protein secretion#GO:0009306;cell communication#GO:0007154;protein transport#GO:0015031;secretion by cell#GO:0032940;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000012416.1|UniProtKB=W5N3T1 W5N3T1 PTHR12842:SF3 FI01459P PROTEIN FAM114A2 LEPOC|Ensembl=ENSLOCG00000003549.1|UniProtKB=W5M765 W5M765 PTHR23253:SF23 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 3 translation initiation factor activity#GO:0003743;RNA binding#GO:0003723;translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000011823.1|UniProtKB=W5N1N5 W5N1N5 PTHR23121:SF10 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 1 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012867.1|UniProtKB=W5N5D7 W5N5D7 PTHR24115:SF434 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF19 isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016140.1|UniProtKB=W5NGY4 W5NGY4 PTHR46298:SF1 ANDROGLOBIN ANDROGLOBIN membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514 LEPOC|Ensembl=ENSLOCG00000009842.1|UniProtKB=W5MUG9 W5MUG9 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017581.1|UniProtKB=W5NM27 W5NM27 PTHR24225:SF52 CHEMOTACTIC RECEPTOR C3A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007055.1|UniProtKB=W5MJH8 W5MJH8 PTHR23239:SF366 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 19 intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000004587.1|UniProtKB=W5MAU4 W5MAU4 PTHR18945:SF53 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3B neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 calcium ion transport#GO:0006816;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;transmembrane transport#GO:0055085;trans-synaptic signaling#GO:0099537;metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268 signaling receptor complex#GO:0043235;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422 LEPOC|Ensembl=ENSLOCG00000003888.1|UniProtKB=W5M8D1 W5M8D1 PTHR25466:SF18 T-LYMPHOCYTE ACTIVATION ANTIGEN BUTYROPHILIN-LIKE PROTEIN 9 ISOFORM X1-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003565.1|UniProtKB=W5M761 W5M761 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 visual perception#GO:0007601;visual system development#GO:0150063;sensory perception of light stimulus#GO:0050953;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014344.1|UniProtKB=W5NAK2 W5NAK2 PTHR46512:SF10 PEPTIDYLPROLYL ISOMERASE FK506-BINDING PROTEIN-LIKE chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000014160.1|UniProtKB=W5N9Y4 W5N9Y4 PTHR11848:SF125 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-1 PROPROTEIN signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cell differentiation#GO:0030154;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to transforming growth factor beta#GO:0071559 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>TGFbeta#P06778;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000003208.1|UniProtKB=W5M5Y9 W5M5Y9 PTHR22382:SF7 RIKEN CDNA 4921504E06 GENE RIKEN CDNA 4921504E06 GENE LEPOC|Ensembl=ENSLOCG00000013127.1|UniProtKB=W5N6B0 W5N6B0 PTHR13530:SF3 TBC1 DOMAIN FAMILY MEMBER 7 TBC1 DOMAIN FAMILY MEMBER 7 molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;binding#GO:0005488 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000012589.1|UniProtKB=W5N4E7 W5N4E7 PTHR23067:SF6 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385C intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007884.1|UniProtKB=W5MMG4 W5MMG4 PTHR24207:SF1 ZYX102 PROTEIN FILAMIN-BINDING LIM PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;stress fiber#GO:0001725;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin filament bundle#GO:0032432;membraneless organelle#GO:0043228;cell junction#GO:0030054;actomyosin#GO:0042641;actin cytoskeleton#GO:0015629;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000001929.1|UniProtKB=W5M1I4 W5M1I4 PTHR10194:SF146 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 1 GTPase-activating protein#PC00257 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Ras#P00886;EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646;Interleukin signaling pathway#P00036>RasGAP#P00975;Angiogenesis#P00005>GAP#P00205;Angiogenesis#P00005>RasGAP#P00190 LEPOC|Ensembl=ENSLOCG00000009969.1|UniProtKB=W5MUY1 W5MUY1 PTHR23065:SF16 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 1 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 system development#GO:0048731;anatomical structure development#GO:0048856;positive regulation of cell projection organization#GO:0031346;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;neuron projection morphogenesis#GO:0048812;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell projection organization#GO:0031344;plasma membrane bounded cell projection organization#GO:0120036;membrane organization#GO:0061024;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;neuron development#GO:0048666;plasma membrane organization#GO:0007009;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;positive regulation of neuron projection development#GO:0010976;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of endocytosis#GO:0030100;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;endomembrane system organization#GO:0010256;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;neuron projection development#GO:0031175;organelle organization#GO:0006996 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Huntington disease#P00029>PACSIN-1#P00802 LEPOC|Ensembl=ENSLOCG00000008018.1|UniProtKB=W5MMY1 W5MMY1 PTHR10654:SF15 CAS SCAFFOLDING PROTEIN BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 1 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;biological regulation#GO:0065007;signaling#GO:0023052;cell migration#GO:0016477;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Integrin signalling pathway#P00034>p130CAS#P00908;CCKR signaling map#P06959>CAS#P07180 LEPOC|Ensembl=ENSLOCG00000000428.1|UniProtKB=W5LWJ0 W5LWJ0 PTHR12623:SF9 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 Gonadotropin-releasing hormone receptor pathway#P06664>NAB#P06801 LEPOC|Ensembl=ENSLOCG00000010208.1|UniProtKB=W5MVU3 W5MVU3 WDR12 PTHR19855:SF40 WD40 REPEAT PROTEIN 12, 37 RIBOSOME BIOGENESIS PROTEIN WDR12 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730 LEPOC|Ensembl=ENSLOCG00000017767.1|UniProtKB=W5NML2 W5NML2 PTHR12002:SF181 CLAUDIN CLAUDIN cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329 bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000015624.1|UniProtKB=W5NF34 W5NF34 PTHR13018:SF38 PROBABLE MEMBRANE PROTEIN DUF221-RELATED MECHANOSENSITIVE CATION CHANNEL TMEM63B ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion-gated channel activity#GO:0022839;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000009441.1|UniProtKB=W5MT30 W5MT30 PTHR11610:SF12 LIPASE LIPASE MEMBER H hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 catabolic process#GO:0009056;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 2-arachidonoylglycerol biosynthesis#P05726>PLA1#P05735 LEPOC|Ensembl=ENSLOCG00000015377.1|UniProtKB=W5NE65 W5NE65 PTHR48099:SF15 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE, MITOCHONDRIAL catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 tetrahydrofolate metabolic process#GO:0046653;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 LEPOC|Ensembl=ENSLOCG00000009883.1|UniProtKB=W5MUM7 W5MUM7 PTHR18956:SF6 HYALURONAN MEDIATED MOTILITY RECEPTOR HYALURONAN MEDIATED MOTILITY RECEPTOR LEPOC|Ensembl=ENSLOCG00000009867.1|UniProtKB=W5MUK1 W5MUK1 PTHR11481:SF112 IMMUNOGLOBULIN FC RECEPTOR BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015850.1|UniProtKB=W5NFV4 W5NFV4 PTHR43146:SF1 CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006785.1|UniProtKB=W5MIK6 W5MIK6 PTHR13869:SF3 MYELIN P0 RELATED SODIUM CHANNEL REGULATORY SUBUNIT BETA-2 transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 regulation of biological quality#GO:0065008;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;membrane depolarization#GO:0051899;regulation of heart contraction#GO:0008016;actin-mediated cell contraction#GO:0070252;muscle system process#GO:0003012;action potential#GO:0001508;regulation of biological process#GO:0050789;heart process#GO:0003015;system process#GO:0003008;heart contraction#GO:0060047;regulation of membrane potential#GO:0042391;cardiac muscle cell contraction#GO:0086003;muscle contraction#GO:0006936;regulation of system process#GO:0044057;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;cardiac muscle cell action potential involved in contraction#GO:0086002;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;actin filament-based movement#GO:0030048;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000002668.1|UniProtKB=W5M440 W5M440 PTHR13986:SF3 PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT CARTILAGE-ASSOCIATED PROTEIN collagen binding#GO:0005518;binding#GO:0005488;protein-containing complex binding#GO:0044877 collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012702.1|UniProtKB=W5N4S1 W5N4S1 PTHR47735:SF11 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 3 voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267 transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016796.1|UniProtKB=W5NJF1 W5NJF1 PTHR24061:SF550 CALCIUM-SENSING RECEPTOR-RELATED OLFACTORY RECEPTOR C FAMILY, B1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016084.1|UniProtKB=W5NGQ8 W5NGQ8 PTHR11214:SF425 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;aminoglycan biosynthetic process#GO:0006023;biosynthetic process#GO:0009058;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000006282.1|UniProtKB=W5MGT0 W5MGT0 PTHR10763:SF23 CELL DIVISION CONTROL PROTEIN 6-RELATED ORIGIN RECOGNITION COMPLEX SUBUNIT 1 binding#GO:0005488;DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nuclear origin of replication recognition complex#GO:0005664;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000003198.1|UniProtKB=W5M5X7 W5M5X7 PTHR10635:SF0 COATOMER SUBUNIT BETA COATOMER SUBUNIT BETA vesicle-mediated transport#GO:0016192;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020 vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000006416.1|UniProtKB=W5MH93 W5MH93 PTHR21377:SF0 PROTEIN FAM210B, MITOCHONDRIAL PROTEIN FAM210B, MITOCHONDRIAL organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000000041.1|UniProtKB=W5LV91 W5LV91 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000013608.1|UniProtKB=W5N825 W5N825 PTHR42918:SF16 LYSYL-TRNA SYNTHETASE LYSINE--TRNA LIGASE RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;binding#GO:0005488;nucleic acid binding#GO:0003676;adenylyltransferase activity#GO:0070566;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874 cell activation#GO:0001775;translation#GO:0006412;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;leukocyte activation#GO:0045321;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;nucleoside phosphate biosynthetic process#GO:1901293;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;tRNA aminoacylation#GO:0043039;organophosphate metabolic process#GO:0019637;amino acid metabolic process#GO:0006520;positive regulation of cell activation#GO:0050867;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune system process#GO:0002376;cell activation involved in immune response#GO:0002263;nucleotide biosynthetic process#GO:0009165;RNA metabolic process#GO:0016070;nucleotide metabolic process#GO:0009117;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;regulation of leukocyte activation#GO:0002694;protein biosynthetic process#GO:0160307;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;positive regulation of leukocyte activation#GO:0002696;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;regulation of macrophage activation#GO:0043030;tRNA aminoacylation for protein translation#GO:0006418;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;gene expression#GO:0010467;myeloid leukocyte activation#GO:0002274 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000004232.1|UniProtKB=W5M9J8 W5M9J8 PTHR12173:SF9 GDNF SUBFAMILY OF TGF-BETA FAMILY ARTEMIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112;neurotrophic factor#PC00163 LEPOC|Ensembl=ENSLOCG00000012840.1|UniProtKB=W5N592 W5N592 PTHR24409:SF455 ZINC FINGER PROTEIN 142 WORNIU nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000005562.1|UniProtKB=W5MEA7 W5MEA7 PTHR24221:SF242 ATP-BINDING CASSETTE SUB-FAMILY B ABC-TYPE OLIGOPEPTIDE TRANSPORTER ABCB9 transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000007287.1|UniProtKB=W5MKB0 W5MKB0 PTHR10424:SF81 VIRAL ENVELOPE PROTEIN ENVELOPE GLYCOPROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000004597.1|UniProtKB=W5MAU9 W5MAU9 PTHR14609:SF1 RING FINGER PROTEIN 219 ORC UBIQUITIN LIGASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of DNA replication#GO:0006275 chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006809.1|UniProtKB=W5MIL2 W5MIL2 PTHR13964:SF37 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000008095.1|UniProtKB=W5MN91 W5MN91 PTHR22881:SF4 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN-CONTAINING PROTEIN 9 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000012615.1|UniProtKB=W5N4H0 W5N4H0 LZTS2 PTHR19354:SF4 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 2-RELATED negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 LEPOC|Ensembl=ENSLOCG00000004286.1|UniProtKB=W5M9R3 W5M9R3 PTHR23097:SF116 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6B transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009035.1|UniProtKB=W5MRK6 W5MRK6 PTHR15708:SF10 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED PROTEIN MTSS 1 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;protein binding#GO:0005515 positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;adherens junction organization#GO:0034332;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;cell-cell junction maintenance#GO:0045217;cellular component organization or biogenesis#GO:0071840;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970;cell-cell junction organization#GO:0045216;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;membrane organization#GO:0061024;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;cell projection assembly#GO:0030031;positive regulation of biological process#GO:0048518 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000013347.1|UniProtKB=W5N739 W5N739 PTHR23146:SF0 LEO1 PROTEIN RNA POLYMERASE-ASSOCIATED PROTEIN LEO1 enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;binding#GO:0005488;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;transcription coregulator activity#GO:0003712;RNA polymerase core enzyme binding#GO:0043175 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000000857.1|UniProtKB=W5LXW6 W5LXW6 PTHR13800:SF5 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 5 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836 cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000009555.1|UniProtKB=W5MTG9 W5MTG9 PTHR12277:SF48 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17B catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096 regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;regulation of synapse organization#GO:0050807;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of postsynapse organization#GO:0099175;negative regulation of biological process#GO:0048519 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000012777.1|UniProtKB=W5N516 W5N516 PTHR15715:SF18 CENTROSOMAL PROTEIN OF 170 KDA CENTROSOMAL PROTEIN OF 170 KDA PROTEIN B protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule anchoring#GO:0034453;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011711.1|UniProtKB=W5N185 W5N185 PTHR23237:SF6 NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1 binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;RNA binding#GO:0003723 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;telomere maintenance via telomere lengthening#GO:0010833;gene expression#GO:0010467;telomere maintenance via telomerase#GO:0007004;RNA processing#GO:0006396;macromolecule modification#GO:0043412;telomere organization#GO:0032200;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;RNA biosynthetic process#GO:0032774;RNA-templated DNA biosynthetic process#GO:0006278;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004788.1|UniProtKB=W5MBK9 W5MBK9 PTHR46289:SF16 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000017796.1|UniProtKB=W5NMP1 W5NMP1 PTHR24245:SF4 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 45-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000014786.1|UniProtKB=W5NC52 W5NC52 PTHR45620:SF5 PDF RECEPTOR-LIKE PROTEIN-RELATED GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010657.1|UniProtKB=W5MXE7 W5MXE7 PTHR24114:SF50 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74A LEPOC|Ensembl=ENSLOCG00000003413.1|UniProtKB=W5M6N7 W5M6N7 PTHR13250:SF1 TF-1 CELL APOPTOSIS RELATED PROTEIN-15 PROGRAMMED CELL DEATH PROTEIN 10 kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;Golgi organization#GO:0007030;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000003486.1|UniProtKB=W5M6X2 W5M6X2 PTHR14499:SF4 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD18 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002552.1|UniProtKB=W5M3R1 W5M3R1 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011622.1|UniProtKB=W5N0X4 W5N0X4 PTHR45652:SF23 GLIAL FIBRILLARY ACIDIC PROTEIN VIMENTIN-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000005762.1|UniProtKB=W5MF00 W5MF00 PTHR21502:SF2 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN 2 small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000012829.1|UniProtKB=W5N579 W5N579 PTHR31183:SF1 TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 53 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001097.1|UniProtKB=W5LYN4 W5LYN4 PTHR32428:SF3 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED PROLINE-RICH PROTEIN 5-LIKE protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;TORC2 signaling#GO:0038203;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;TOR signaling#GO:0031929;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 TOR complex#GO:0038201;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000004684.1|UniProtKB=W5MB50 W5MB50 PTHR14759:SF38 STOP PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 6 HOMOLOG ISOFORM X1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;cis-Golgi network#GO:0005801;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 LEPOC|Ensembl=ENSLOCG00000012309.1|UniProtKB=W5N3E3 W5N3E3 PTHR12106:SF44 SORTILIN RELATED SORTILIN Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle organization#GO:0016050;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;vesicle-mediated transport#GO:0016192;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;localization#GO:0051179;Golgi to endosome transport#GO:0006895;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;endocytosis#GO:0006897 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009110.1|UniProtKB=W5MRV3 W5MRV3 PTHR24126:SF3 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000018159.1|UniProtKB=W5NNQ1 W5NNQ1 PTHR15532:SF2 FAMILY NOT NAMED DERMATAN-SULFATE EPIMERASE-LIKE PROTEIN isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854 primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 LEPOC|Ensembl=ENSLOCG00000007995.1|UniProtKB=W5MMV8 W5MMV8 PTHR10110:SF90 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 3 monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739 plasma membrane region#GO:0098590;brush border membrane#GO:0031526;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;apical plasma membrane#GO:0016324;membrane#GO:0016020;cell periphery#GO:0071944;brush border#GO:0005903;cell projection membrane#GO:0031253;cluster of actin-based cell projections#GO:0098862;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000015254.1|UniProtKB=W5NDR1 W5NDR1 PTHR16209:SF7 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN-BINDING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010674.1|UniProtKB=W5MXG5 W5MXG5 PTHR46272:SF5 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTOR 142-RELATED regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 LEPOC|Ensembl=ENSLOCG00000000085.1|UniProtKB=W5LVE3 W5LVE3 PTHR12346:SF1 SIN3B-RELATED PAIRED AMPHIPATHIC HELIX PROTEIN SIN3B transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>Sin3A#P00771 LEPOC|Ensembl=ENSLOCG00000002671.1|UniProtKB=W5M445 W5M445 PTHR11730:SF120 AMMONIUM TRANSPORTER RH BLOOD GROUP, D ANTIGEN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 homeostatic process#GO:0042592;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006193.1|UniProtKB=W5MGI4 W5MGI4 PTHR14167:SF68 SH3 DOMAIN-CONTAINING ENDOPHILIN-B2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000624.1|UniProtKB=W5LX33 W5LX33 PTHR12763:SF56 FAMILY NOT NAMED MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM14 ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585 organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000008578.1|UniProtKB=W5MPX6 W5MPX6 PTHR11830:SF16 40S RIBOSOMAL PROTEIN S3A UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;structural constituent of ribosome#GO:0003735;peptidase activity#GO:0008233;structural molecule activity#GO:0005198;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;post-translational protein modification#GO:0043687;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;translation#GO:0006412 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000010786.1|UniProtKB=W5MXW2 W5MXW2 PTHR22950:SF22 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 3 L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171;basic amino acid transmembrane transporter activity#GO:0015174;aromatic amino acid transmembrane transporter activity#GO:0015173;carboxylic acid transmembrane transporter activity#GO:0046943 nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 amino acid transporter#PC00046;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000001118.1|UniProtKB=W5LYQ5 W5LYQ5 PTHR10131:SF152 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 6 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein-macromolecule adaptor activity#GO:0030674;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;signaling adaptor activity#GO:0035591;transferase activity#GO:0016740;catalytic activity#GO:0003824;molecular adaptor activity#GO:0060090;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;response to bacterium#GO:0009617;lipopolysaccharide-mediated signaling pathway#GO:0031663;cell communication#GO:0007154;regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response#GO:0006955;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;cellular response to molecule of bacterial origin#GO:0071219;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;cellular process#GO:0009987;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;response to lipid#GO:0033993;defense response to other organism#GO:0098542;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496 cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cytoplasmic side of membrane#GO:0098562;side of membrane#GO:0098552;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 p38 MAPK pathway#P05918>TRAF6#P06038;p53 pathway#P00059>TRAF#P04620;Apoptosis signaling pathway#P00006>TRAF2#P00306;Toll receptor signaling pathway#P00054>TRAF6#P01371 LEPOC|Ensembl=ENSLOCG00000005585.1|UniProtKB=W5MED3 W5MED3 PTHR47266:SF6 ENDONUCLEASE-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000002883.1|UniProtKB=W5M4V6 W5M4V6 PTHR24020:SF39 COLLAGEN ALPHA COLLAGEN ALPHA-1(XX) CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000001540.1|UniProtKB=W5M058 W5M058 PTHR46940:SF1 NKAP DOMAIN-CONTAINING 1 NKAP DOMAIN CONTAINING 1 LEPOC|Ensembl=ENSLOCG00000016319.1|UniProtKB=W5NHN6 W5NHN6 PTHR13578:SF11 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL2-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;signaling receptor binding#GO:0005102;binding#GO:0005488 developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of RNA metabolic process#GO:0051254;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;PcG protein complex#GO:0031519 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000007845.1|UniProtKB=W5MMB5 W5MMB5 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED binding#GO:0005488;signaling receptor activity#GO:0038023;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008456.1|UniProtKB=W5MPI1 W5MPI1 PTHR10177:SF254 CYCLINS CYCLIN-A1 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 LEPOC|Ensembl=ENSLOCG00000008613.1|UniProtKB=W5MQ25 W5MQ25 PTHR11909:SF151 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-3 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 LEPOC|Ensembl=ENSLOCG00000017377.1|UniProtKB=W5NLH3 W5NLH3 PTHR24231:SF2 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 1 protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;signaling receptor activity#GO:0038023;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;G protein-coupled receptor binding#GO:0001664;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;molecular transducer activity#GO:0060089;anion binding#GO:0043168;small molecule binding#GO:0036094;signaling receptor binding#GO:0005102;ion binding#GO:0043167;nucleotide binding#GO:0000166;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011418.1|UniProtKB=W5N075 W5N075 PTHR12329:SF12 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 3 nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;cellular homeostasis#GO:0019725;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of protein stability#GO:0031647;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;homeostatic process#GO:0042592;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 Apoptosis signaling pathway#P00006>Bag#P00278 LEPOC|Ensembl=ENSLOCG00000011072.1|UniProtKB=W5MZ08 W5MZ08 PTHR24020:SF49 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXVIII) CHAIN cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000004390.1|UniProtKB=W5MA46 W5MA46 PTHR12560:SF6 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 ceramide metabolic process#GO:0006672;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000005990.1|UniProtKB=W5MFT7 W5MFT7 PTHR12345:SF17 SYNTENIN RELATED SDCBP PROTEIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001794.1|UniProtKB=W5M121 W5M121 PTHR13936:SF15 PROFILIN PROFILIN-2 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;positive regulation of actin filament bundle assembly#GO:0032233;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 LEPOC|Ensembl=ENSLOCG00000010783.1|UniProtKB=W5MXW1 W5MXW1 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010320.1|UniProtKB=W5MWB2 W5MWB2 PTHR11905:SF14 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 22 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;cell junction#GO:0030054 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000005807.1|UniProtKB=W5MF63 W5MF63 PTHR24115:SF937 KINESIN-RELATED KINESIN HEAVY CHAIN ISOFORM 5A isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657 synaptic vesicle transport#GO:0048489;axo-dendritic transport#GO:0008088;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle localization#GO:0097479;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;mitochondrion localization#GO:0051646;microtubule-based process#GO:0007017;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;axonal transport#GO:0098930;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;anterograde axonal transport#GO:0008089 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000006582.1|UniProtKB=W5MHU1 W5MHU1 PTHR11662:SF201 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER 2 carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;acidic amino acid transmembrane transporter activity#GO:0015172;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310 trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;localization#GO:0051179;cell communication#GO:0007154;regulation of synapse structure or activity#GO:0050803;cellular localization#GO:0051641;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192 synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;presynapse#GO:0098793;cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 secondary carrier transporter#PC00258 Ionotropic glutamate receptor pathway#P00037>Vglut#P01021 LEPOC|Ensembl=ENSLOCG00000014886.1|UniProtKB=W5NCH1 W5NCH1 PTHR10210:SF130 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 1-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012192.1|UniProtKB=W5N2Y7 W5N2Y7 PTHR12975:SF6 TRANSPORT PROTEIN TRAPP TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;TRAPP complex#GO:0030008;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000017669.1|UniProtKB=W5NMB5 W5NMB5 PTHR24232:SF85 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008777.1|UniProtKB=W5MQM7 W5MQM7 PTHR10239:SF28 ISTHMIN-2 ISTHMIN-2 LEPOC|Ensembl=ENSLOCG00000011898.1|UniProtKB=W5N1X3 W5N1X3 PTHR11595:SF55 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER EF-HAND AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000013537.1|UniProtKB=W5N7T7 W5N7T7 PTHR46227:SF4 GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP GLUTAMATE RECEPTOR-INTERACTING PROTEIN 2 protein localization to cell periphery#GO:1990778;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein localization to synapse#GO:0035418;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endosome to plasma membrane protein transport#GO:0099638;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;protein localization to cell junction#GO:1902414;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;regulation of biological quality#GO:0065008;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;endocytic recycling#GO:0032456 LEPOC|Ensembl=ENSLOCG00000017483.1|UniProtKB=W5NLS9 W5NLS9 PTHR24072:SF150 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOG protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;establishment or maintenance of cell polarity#GO:0007163;regulation of biological quality#GO:0065008;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 small GTPase#PC00208;G-protein#PC00020 EGF receptor signaling pathway#P00018>Rac#P00564 LEPOC|Ensembl=ENSLOCG00000014492.1|UniProtKB=W5NB28 W5NB28 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899 developmental process#GO:0032502;sperm-egg recognition#GO:0035036;cell-cell recognition#GO:0009988;cellular developmental process#GO:0048869;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;single fertilization#GO:0007338;oogenesis#GO:0048477;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;cell recognition#GO:0008037;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;binding of sperm to zona pellucida#GO:0007339;anatomical structure development#GO:0048856;germ cell development#GO:0007281;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;reproductive process#GO:0022414;fertilization#GO:0009566;gamete generation#GO:0007276;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 LEPOC|Ensembl=ENSLOCG00000017415.1|UniProtKB=W5NLL1 W5NLL1 PTHR46169:SF2 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A E3 SUMO-PROTEIN LIGASE ZBED1 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003317.1|UniProtKB=W5M6B4 W5M6B4 PTHR11362:SF151 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 1 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 protease inhibitor#PC00191 EGF receptor signaling pathway#P00018>RKIP#P00548;FGF signaling pathway#P00021>RKIP#P00630 LEPOC|Ensembl=ENSLOCG00000013825.1|UniProtKB=W5N8T9 W5N8T9 PTHR28594:SF1 ATR-INTERACTING PROTEIN ATR-INTERACTING PROTEIN DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 LEPOC|Ensembl=ENSLOCG00000011378.1|UniProtKB=W5N024 W5N024 PTHR35670:SF1 TRANSMEMBRANE PROTEIN 81 TRANSMEMBRANE PROTEIN 81 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 fertilization#GO:0009566;reproductive process#GO:0022414;single fertilization#GO:0007338;cellular process#GO:0009987;cell-cell recognition#GO:0009988;sperm-egg recognition#GO:0035036;sexual reproduction#GO:0019953;cell recognition#GO:0008037 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000005154.1|UniProtKB=W5MD03 W5MD03 PTHR11226:SF1 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 2 UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000008221.1|UniProtKB=W5MNM4 W5MNM4 PTHR11188:SF14 ARRESTIN DOMAIN CONTAINING PROTEIN THIOREDOXIN-INTERACTING PROTEIN enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 response to stimulus#GO:0050896;response to oxidative stress#GO:0006979;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008229.1|UniProtKB=W5MNN3 W5MNN3 PTHR12411:SF992 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN O cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016483.1|UniProtKB=W5NIB9 W5NIB9 PTHR21497:SF28 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR2 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003884.1|UniProtKB=W5M8D7 W5M8D7 PTHR21646:SF44 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 31 cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000014641.1|UniProtKB=W5NBL2 W5NBL2 PTHR10454:SF155 CASPASE CASPASE-15 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of neuron apoptotic process#GO:0043523;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;positive regulation of neuron apoptotic process#GO:0043525;epidermis development#GO:0008544;developmental process#GO:0032502;regulation of apoptotic process#GO:0042981 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014523.1|UniProtKB=W5NB68 W5NB68 PTHR11537:SF174 VOLTAGE-GATED POTASSIUM CHANNEL A-TYPE VOLTAGE-GATED POTASSIUM CHANNEL KCND1 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811 cation channel complex#GO:0034703;synaptic membrane#GO:0097060;voltage-gated potassium channel complex#GO:0008076;cell junction#GO:0030054;transporter complex#GO:1990351;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;dendritic tree#GO:0097447;transmembrane transporter complex#GO:1902495;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell body#GO:0044297;dendritic spine#GO:0043197;plasma membrane protein complex#GO:0098797;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000000753.1|UniProtKB=W5LXI2 W5LXI2 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009613.1|UniProtKB=W5MTN0 W5MTN0 PTHR24115:SF352 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF20A protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000015333.1|UniProtKB=W5NE12 W5NE12 PTHR18945:SF211 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-4 monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;organelle#GO:0043226;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic membrane#GO:0097060;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;cell junction#GO:0030054 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000000044.1|UniProtKB=W5LV95 W5LV95 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010793.1|UniProtKB=W5MXW6 W5MXW6 PTHR24356:SF143 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE 32A catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002051.1|UniProtKB=W5M1X3 W5M1X3 PTHR21035:SF2 28S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS26 intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006876.1|UniProtKB=W5MIV9 W5MIV9 PTHR24410:SF40 HL07962P-RELATED BTB DOMAIN-CONTAINING PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 regulation of lipid metabolic process#GO:0019216;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016650.1|UniProtKB=W5NIV7 W5NIV7 PTHR21608:SF8 KINESIN-LIKE PROTEIN CG14535 KINESIN-LIKE PROTEIN KIF26B binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;regulation of locomotion#GO:0040012;tube development#GO:0035295;biological regulation#GO:0065007;kidney development#GO:0001822;renal system development#GO:0072001;animal organ development#GO:0048513;developmental growth#GO:0048589;multicellular organism development#GO:0007275;morphogenesis of an epithelium#GO:0002009;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of neuron migration#GO:2001222;growth#GO:0040007;regulation of cell migration#GO:0030334;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;tube morphogenesis#GO:0035239;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;regulation of cell motility#GO:2000145;developmental growth involved in morphogenesis#GO:0060560;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108 LEPOC|Ensembl=ENSLOCG00000004364.1|UniProtKB=W5MA20 W5MA20 PTHR14918:SF3 KICSTOR COMPLEX PROTEIN SZT2 KICSTOR COMPLEX PROTEIN SZT2 negative regulation of cellular process#GO:0048523;negative regulation of TORC1 signaling#GO:1904262;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;multicellular organism development#GO:0007275;regulation of TORC1 signaling#GO:1903432;response to nutrient levels#GO:0031667;regulation of TOR signaling#GO:0032006;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;nervous system development#GO:0007399;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;anatomical structure development#GO:0048856;negative regulation of intracellular signal transduction#GO:1902532;system development#GO:0048731;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosomal membrane#GO:0005765;microbody#GO:0042579;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000012078.1|UniProtKB=W5N2J8 W5N2J8 PTHR28673:SF1 TRANSMEMBRANE PROTEIN 108 TRANSMEMBRANE PROTEIN 108 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell growth#GO:0016049;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;nervous system development#GO:0007399;neuron projection development#GO:0031175;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular localization#GO:0051641;neuron development#GO:0048666;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;generation of neurons#GO:0048699;retrograde axonal transport#GO:0008090;postsynaptic density organization#GO:0097106;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;developmental growth#GO:0048589;neurogenesis#GO:0022008;intracellular transport#GO:0046907;developmental process#GO:0032502;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;axo-dendritic transport#GO:0008088;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;postsynaptic specialization organization#GO:0099084;axonal transport#GO:0098930;synapse organization#GO:0050808;cell junction organization#GO:0034330;microtubule-based movement#GO:0007018;postsynapse organization#GO:0099173;developmental cell growth#GO:0048588 cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;postsynapse#GO:0098794;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;postsynaptic density#GO:0014069;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;axon#GO:0030424;endomembrane system#GO:0012505;neuron to neuron synapse#GO:0098984;cytoplasmic vesicle membrane#GO:0030659;postsynaptic specialization#GO:0099572;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;neuron projection#GO:0043005;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000006210.1|UniProtKB=W5MGJ4 W5MGJ4 PTHR18902:SF27 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED CENTROSOMAL PROTEIN OF 164 KDA cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 protein-containing complex#GO:0032991;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;ciliary transition fiber#GO:0097539;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000014921.1|UniProtKB=W5NCL6 W5NCL6 PTHR15653:SF1 STRIATIN STRIATIN-4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 dendritic tree#GO:0097447;dendrite#GO:0030425;cell junction#GO:0030054;cell body#GO:0044297;neuron projection#GO:0043005;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;synapse#GO:0045202 LEPOC|Ensembl=ENSLOCG00000002713.1|UniProtKB=W5M484 W5M484 PTHR14429:SF20 FIBROSIN FAMILY MEMBER FIBROSIN-1-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000017028.1|UniProtKB=W5NK86 W5NK86 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 14A ISOFORM X1-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008251.1|UniProtKB=W5MNQ5 W5MNQ5 PTHR15316:SF1 SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED SPLICING FACTOR 3A SUBUNIT 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000010290.1|UniProtKB=W5MW44 W5MW44 PTHR15192:SF4 PROTEIN CBG05349 OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 2 growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 negative regulation of cellular process#GO:0048523;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of growth#GO:0040008;regulation of cellular process#GO:0050794;regulation of cell growth#GO:0001558;regulation of cellular component organization#GO:0051128;negative regulation of cell growth#GO:0030308;biological regulation#GO:0065007 LEPOC|Ensembl=ENSLOCG00000009746.1|UniProtKB=W5MU48 W5MU48 PTHR12303:SF14 CARNOSINE N-METHYLTRANSFERASE PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE CARNMT1 catalytic activity#GO:0003824;transferase activity#GO:0016740;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009544.1|UniProtKB=W5MTF4 W5MTF4 PTHR46005:SF2 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 5 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;regulation of cell projection organization#GO:0031344;regulation of anatomical structure size#GO:0090066;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;regulation of cell size#GO:0008361;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cellular response to stimulus#GO:0051716;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000012861.1|UniProtKB=W5N5C7 W5N5C7 PTHR13225:SF3 MISEXPRESSION SUPPRESSOR OF RAS 6 UPF0489 PROTEIN C5ORF22 LEPOC|Ensembl=ENSLOCG00000014478.1|UniProtKB=W5NB25 W5NB25 PTHR11533:SF305 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171;catabolic process#GO:0009056;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004352.1|UniProtKB=W5M9Z3 W5M9Z3 PTHR47960:SF7 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 RNA HELICASE RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;cytoplasmic stress granule assembly#GO:0034063;regulation of macromolecule metabolic process#GO:0060255;P-body assembly#GO:0033962;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;membraneless organelle assembly#GO:0140694;negative regulation of biological process#GO:0048519;negative regulation of translation#GO:0017148;organelle assembly#GO:0070925 organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000016135.1|UniProtKB=W5NGX2 W5NGX2 PTHR45993:SF5 B-CELL LYMPHOMA/LEUKEMIA 11 BCL11 TRANSCRIPTION FACTOR A RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of developmental process#GO:0050793;regulation of cellular component organization#GO:0051128;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;regulation of gene expression#GO:0010468;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biosynthetic process#GO:0009889;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of neuron projection development#GO:0010975;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001453.1|UniProtKB=W5LZV2 W5LZV2 PTHR24413:SF239 SPECKLE-TYPE POZ PROTEIN RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 3 enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis#GO:0030162;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009479.1|UniProtKB=W5MT79 W5MT79 PTHR23282:SF116 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000016259.1|UniProtKB=W5NHE4 W5NHE4 PTHR21723:SF2 RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 RIC3 RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 N-TERMINAL DOMAIN-CONTAINING PROTEIN cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000006568.1|UniProtKB=W5MHS8 W5MHS8 PTHR15502:SF7 CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED CALCINEURIN-BINDING PROTEIN CABIN-1 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 phosphatase inhibitor#PC00183 LEPOC|Ensembl=ENSLOCG00000001487.1|UniProtKB=W5LZY7 W5LZY7 PTHR23036:SF193 CYTOKINE RECEPTOR FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009137.1|UniProtKB=W5MRY0 W5MRY0 PTHR12771:SF47 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 2 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular component assembly#GO:0022607;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;cell projection organization#GO:0030030;regulation of response to biotic stimulus#GO:0002831;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cilium organization#GO:0044782;organelle assembly#GO:0070925;regulation of defense response#GO:0031347 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008166.1|UniProtKB=W5MNF2 W5MNF2 PTHR11028:SF6 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324 chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;localization#GO:0051179;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 intracellular organelle#GO:0043229;ATPase complex#GO:1904949;endosome#GO:0005768;early endosome#GO:0005769;ATPase dependent transmembrane transport complex#GO:0098533;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;proton-transporting two-sector ATPase complex#GO:0016469;lytic vacuole#GO:0000323;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane protein complex#GO:0098796;vesicle#GO:0031982;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000005878.1|UniProtKB=W5MFE3 W5MFE3 PTHR24367:SF320 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH GLIOMA-INACTIVATED PROTEIN 1 animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;myelination#GO:0042552;system development#GO:0048731;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005677.1|UniProtKB=W5MEP6 W5MEP6 PTHR13430:SF4 AUTOPHAGY-RELATED PROTEIN 13 AUTOPHAGY-RELATED PROTEIN 13 enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 cellular component organization#GO:0016043;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840 protein kinase complex#GO:1902911;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;autophagosome#GO:0005776;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000016114.1|UniProtKB=W5NGV1 W5NGV1 PTHR44468:SF2 COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR-RELATED V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 8B LEPOC|Ensembl=ENSLOCG00000015960.1|UniProtKB=W5NG93 W5NG93 PTHR20338:SF8 NUCLEAR RESPIRATORY FACTOR 1 NUCLEAR RESPIRATORY FACTOR 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008297.1|UniProtKB=W5MNX3 W5MNX3 PTHR10686:SF38 FOLATE TRANSPORTER SOLUTE CARRIER FAMILY 19 MEMBER 3B establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003105.1|UniProtKB=W5M5K0 W5M5K0 PTHR21386:SF0 INSCUTEABLE PROTEIN INSCUTEABLE HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cytoskeletal adaptor activity#GO:0008093 regulation of cellular process#GO:0050794;localization#GO:0051179;intracellular protein localization#GO:0008104;biological regulation#GO:0065007;regulation of cell division#GO:0051302;macromolecule localization#GO:0033036;regulation of biological process#GO:0050789 cell periphery#GO:0071944;cell cortex#GO:0005938;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000229.1|UniProtKB=W5LVU5 W5LVU5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010164.1|UniProtKB=W5MVY1 W5MVY1 PTHR12268:SF25 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;regulation of biological process#GO:0050789;regulation of muscle system process#GO:0090257;muscle cell development#GO:0055001;system development#GO:0048731;muscle tissue development#GO:0060537;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cellular process#GO:0009987;skeletal muscle tissue development#GO:0007519;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;neuron differentiation#GO:0030182;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;regulation of system process#GO:0044057;muscle organ development#GO:0007517 sarcolemma#GO:0042383;cell junction#GO:0030054;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell projection#GO:0042995 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012912.1|UniProtKB=W5N5J2 W5N5J2 PTHR12703:SF4 TRANSMEMBRANE PROTEIN 33 TRANSMEMBRANE PROTEIN 33 cellular process#GO:0009987;nuclear membrane organization#GO:0071763;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;endoplasmic reticulum tubular network organization#GO:0071786;endoplasmic reticulum membrane organization#GO:0090158;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016547.1|UniProtKB=W5NIH8 W5NIH8 PTHR11360:SF25 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 2 monocarboxylic acid transmembrane transporter activity#GO:0008028;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004729.1|UniProtKB=W5MBB3 W5MBB3 PTHR12317:SF82 DIACYLGLYCEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 biosynthetic process#GO:0009058;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000001551.1|UniProtKB=W5M072 W5M072 PTHR13847:SF193 SARCOSINE DEHYDROGENASE-RELATED PYRUVATE DEHYDROGENASE PHOSPHATASE REGULATORY SUBUNIT, MITOCHONDRIAL mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000010711.1|UniProtKB=W5MXM2 W5MXM2 PTHR32086:SF0 FANCONI ANEMIA GROUP D2 PROTEIN FANCONI ANEMIA GROUP D2 PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;primary metabolic process#GO:0044238;homologous recombination#GO:0035825;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA integrity checkpoint signaling#GO:0031570;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;meiotic chromosome segregation#GO:0045132;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;meiosis I cell cycle process#GO:0061982;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organelle fission#GO:0048285;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;homologous chromosome pairing at meiosis#GO:0007129;cell cycle checkpoint signaling#GO:0000075;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;double-strand break repair#GO:0006302;negative regulation of cell cycle#GO:0045786;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;signaling#GO:0023052;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930 condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000012779.1|UniProtKB=W5N513 W5N513 PTHR34524:SF6 CALCYPHOSIN CALCYPHOSINE LIKE calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000002712.1|UniProtKB=W5M472 W5M472 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002466.1|UniProtKB=W5M3G6 W5M3G6 PTHR14095:SF1 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT BETA protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000007823.1|UniProtKB=W5MM89 W5MM89 PTHR24115:SF486 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2A cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887 cilium organization#GO:0044782;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;microtubule-based movement#GO:0007018;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000003090.1|UniProtKB=W5M5I0 W5M5I0 NTHL1 PTHR43286:SF7 ENDONUCLEASE III-LIKE PROTEIN 1 ENDONUCLEASE III-LIKE PROTEIN 1 catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;DNA N-glycosylase activity#GO:0019104 response to stimulus#GO:0050896;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA glycosylase#PC00010;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000005474.1|UniProtKB=W5ME13 W5ME13 PTHR15688:SF1 KINETOCHORE-ASSOCIATED PROTEIN 1 KINETOCHORE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488;enzyme binding#GO:0019899 negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;kinetochore assembly#GO:0051382;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;negative regulation of cell cycle#GO:0045786;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular component assembly#GO:0022607;mitotic spindle assembly checkpoint signaling#GO:0007094;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;organelle fission#GO:0048285;organelle assembly#GO:0070925;negative regulation of chromosome organization#GO:2001251;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;intracellular protein localization#GO:0008104;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of mitotic cell cycle#GO:0007346;mitotic sister chromatid segregation#GO:0000070;macromolecule localization#GO:0033036;nuclear division#GO:0000280;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of chromosome segregation#GO:0051985;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of sister chromatid segregation#GO:0033046;regulation of mitotic sister chromatid segregation#GO:0033047;kinetochore organization#GO:0051383;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;protein localization to kinetochore#GO:0034501 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;kinetochore#GO:0000776;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000008308.1|UniProtKB=W5MNY4 W5MNY4 PTHR10625:SF19 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 12 deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096;histone modifying activity#GO:0140993;deacylase activity#GO:0160215;catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407 chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular process#GO:0009987;regulation of biological process#GO:0050789;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 LEPOC|Ensembl=ENSLOCG00000003564.1|UniProtKB=W5M762 W5M762 PTHR23167:SF3 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED CYTOSPIN-B organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010128.1|UniProtKB=W5MVK0 W5MVK0 PTHR24351:SF198 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000908.1|UniProtKB=W5LY01 W5LY01 PTHR33664:SF1 RCG26366 DYNEIN AXONEMAL ASSEMBLY FACTOR 9 LEPOC|Ensembl=ENSLOCG00000012330.1|UniProtKB=W5N3H6 W5N3H6 PTHR24355:SF15 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 6 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK6#P05939;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GPRK#P00840 LEPOC|Ensembl=ENSLOCG00000003857.1|UniProtKB=W5M897 W5M897 PTHR11850:SF80 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN PKNOX1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;tube development#GO:0035295;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel morphogenesis#GO:0048514;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;angiogenesis#GO:0001525 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>Prep1#P06829 LEPOC|Ensembl=ENSLOCG00000015824.1|UniProtKB=W5NFS2 W5NFS2 PTHR12613:SF2 ERO1-RELATED ERO1-LIKE PROTEIN BETA oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;response to unfolded protein#GO:0006986;protein metabolic process#GO:0019538;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007928.1|UniProtKB=W5MML8 W5MML8 PTHR45753:SF8 ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL ORNITHINE TRANSCARBAMYLASE, MITOCHONDRIAL transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220 Arginine biosynthesis#P02728>Ornithine carbamoyl transferase#P02846 LEPOC|Ensembl=ENSLOCG00000001995.1|UniProtKB=W5M1R1 W5M1R1 PTHR43563:SF26 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 phenol-containing compound metabolic process#GO:0018958;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056;amine catabolic process#GO:0009310;metabolic process#GO:0008152;serotonin metabolic process#GO:0042428 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidase#PC00175;oxidoreductase#PC00176 Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067;Dopamine receptor mediated signaling pathway#P05912>MAO#P05963;5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 LEPOC|Ensembl=ENSLOCG00000017018.1|UniProtKB=W5NK75 W5NK75 FBLN1 PTHR24034:SF97 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-1 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000017948.1|UniProtKB=W5NN42 W5NN42 PTHR24369:SF178 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000018063.1|UniProtKB=W5NNF5 W5NNF5 PTHR28615:SF2 PAK4-INHIBITOR INKA1-RELATED PAK4-INHIBITOR INKA2 enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011646.1|UniProtKB=W5N0Z5 W5N0Z5 PTHR18945:SF213 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-1 gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic anion transmembrane transporter activity#GO:0008509;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 postsynaptic specialization#GO:0099572;organelle#GO:0043226;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;synaptic membrane#GO:0097060 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000000730.1|UniProtKB=W5LXG4 W5LXG4 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009203.1|UniProtKB=W5MS66 W5MS66 PTHR15944:SF2 FARNESYLCYSTEINE LYASE PRENYLCYSTEINE OXIDASE 1-LIKE oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 lyase#PC00144;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018124.1|UniProtKB=W5NNL6 W5NNL6 PTHR10129:SF53 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFAA DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000017983.1|UniProtKB=W5NN75 W5NN75 PTHR24248:SF177 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE RECEPTOR D7 neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled dopamine receptor signaling pathway#GO:0007212;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;adrenergic receptor signaling pathway#GO:0071875;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017163.1|UniProtKB=W5NKQ6 W5NKQ6 PTHR41142:SF1 SI:DKEY-16J16.4 SI:DKEY-16J16.4 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;peripheral nervous system development#GO:0007422;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166 LEPOC|Ensembl=ENSLOCG00000011220.1|UniProtKB=W5MZH3 W5MZH3 PTHR10768:SF0 60S RIBOSOMAL PROTEIN L37 RIBOSOMAL PROTEIN L37 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000006232.1|UniProtKB=W5MGL4 W5MGL4 PTHR19433:SF72 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA CHAIN MC.7.G5-RELATED response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011794.1|UniProtKB=W5N1J9 W5N1J9 PTHR45905:SF4 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1 protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme binding#GO:0019899;binding#GO:0005488 macromolecule localization#GO:0033036;cellular process#GO:0009987;Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;post-Golgi vesicle-mediated transport#GO:0006892 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009350.1|UniProtKB=W5MSP6 W5MSP6 PTHR24334:SF2 HOMEOBOX PROTEIN GBX HOMEOBOX PROTEIN GBX-1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of developmental process#GO:0050793;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007600.1|UniProtKB=W5MLF8 W5MLF8 PTHR46176:SF3 LD21662P PROTEIN FAM76B membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear speck#GO:0016607;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000015146.1|UniProtKB=W5NDD9 W5NDD9 PTHR10766:SF176 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER localization within membrane#GO:0051668;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015133.1|UniProtKB=W5NDC2 W5NDC2 PTHR21328:SF23 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP6 NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;transferase activity#GO:0016740;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;kinase activator activity#GO:0019209;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;protein kinase activator activity#GO:0030295;glycosyltransferase activity#GO:0016757;molecular function regulator activity#GO:0098772 response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;nucleus#GO:0005634;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000002559.1|UniProtKB=W5M3P5 W5M3P5 PTHR47139:SF4 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9A ISOFORM X1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;biological regulation#GO:0065007 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001615.1|UniProtKB=W5M0F1 W5M0F1 PTHR23238:SF25 RNA BINDING PROTEIN TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012316.1|UniProtKB=W5N3E5 W5N3E5 PTHR19443:SF84 HEXOKINASE HEXOKINASE hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200 purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;glucose homeostasis#GO:0042593;ADP catabolic process#GO:0046032;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;pyruvate metabolic process#GO:0006090;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;ADP metabolic process#GO:0046031;cellular homeostasis#GO:0019725;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;intracellular glucose homeostasis#GO:0001678;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;carbohydrate homeostasis#GO:0033500;energy derivation by oxidation of organic compounds#GO:0015980;intracellular chemical homeostasis#GO:0055082;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleotide catabolic process#GO:0006195;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154 organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytosol#GO:0005829;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;cytoplasmic side of membrane#GO:0098562;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011708.1|UniProtKB=W5N191 W5N191 PTHR45589:SF4 WD REPEAT DOMAIN 62, ISOFORM G MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1 ISOFORM X1 regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010972.1|UniProtKB=W5MYJ9 W5MYJ9 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001369.1|UniProtKB=W5LZL4 W5LZL4 PTHR12087:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;molecular adaptor activity#GO:0060090;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688;protein-macromolecule adaptor activity#GO:0030674 DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139 chromosome#GO:0005694;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nuclear origin of replication recognition complex#GO:0005664;membraneless organelle#GO:0043228;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513 replication origin binding protein#PC00199;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001544.1|UniProtKB=W5M092 W5M092 PTHR24023:SF1143 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXIV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000003361.1|UniProtKB=W5M6G4 W5M6G4 PTHR21547:SF0 CLUSTERIN ASSOCIATED PROTEIN 1 CLUSTERIN-ASSOCIATED PROTEIN 1 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000011934.1|UniProtKB=W5N217 W5N217 PTHR33904:SF1 ESSENTIAL MCU REGULATOR, MITOCHONDRIAL ESSENTIAL MCU REGULATOR, MITOCHONDRIAL intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;homeostatic process#GO:0042592;mitochondrial calcium ion homeostasis#GO:0051560;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873 organelle membrane#GO:0031090;transporter complex#GO:1990351;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;calcium channel complex#GO:0034704;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796 LEPOC|Ensembl=ENSLOCG00000000062.1|UniProtKB=W5LVB5 W5LVB5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000451.1|UniProtKB=W5LWI5 W5LWI5 PTHR24208:SF118 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1-ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013742.1|UniProtKB=W5N8J1 W5N8J1 PTHR10454:SF198 CASPASE CASPASE-3 catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function activator activity#GO:0140677 programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cell death#GO:0008219;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;keratinocyte differentiation#GO:0030216;homeostasis of number of cells#GO:0048872;erythrocyte differentiation#GO:0030218;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;system development#GO:0048731;positive regulation of cellular process#GO:0048522;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;biological regulation#GO:0065007;hemopoiesis#GO:0030097;positive regulation of neuron apoptotic process#GO:0043525;epidermis development#GO:0008544;developmental process#GO:0032502;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;neurogenesis#GO:0022008;regulation of programmed cell death#GO:0043067;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;positive regulation of programmed cell death#GO:0043068;cell development#GO:0048468;immune system process#GO:0002376;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of neuron apoptotic process#GO:0043523;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;skin development#GO:0043588;nervous system development#GO:0007399;metabolic process#GO:0008152;neuron differentiation#GO:0030182;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;multicellular organism development#GO:0007275;animal organ development#GO:0048513 intracellular anatomical structure#GO:0005622;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;protease#PC00190 CCKR signaling map#P06959>Pro-caspase-3#P07231;Apoptosis signaling pathway#P00006>Caspase 3#P00305;FAS signaling pathway#P00020>Caspase3#P00599;CCKR signaling map#P06959>Caspase-3#P07108;FAS signaling pathway#P00020>Pro-Caspase3#P00608;Huntington disease#P00029>Caspase 3#P00812 LEPOC|Ensembl=ENSLOCG00000014141.1|UniProtKB=W5N9V9 W5N9V9 PTHR14198:SF4 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 5 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000015189.1|UniProtKB=W5NDI5 W5NDI5 PTHR12103:SF18 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 4 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004783.1|UniProtKB=W5MBH8 W5MBH8 PTHR10822:SF12 GLYPICAN GLYPICAN-5 regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;regulation of protein localization to membrane#GO:1905475;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cell migration#GO:0016477;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of localization#GO:0032879;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of protein localization#GO:0032880 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016120.1|UniProtKB=W5NGV3 W5NGV3 PTHR12129:SF15 HEPARAN SULFATE 2-O-SULFOTRANSFERASE URONYL 2-SULFOTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001571.1|UniProtKB=W5M087 W5M087 PTHR12232:SF1 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 LEPOC|Ensembl=ENSLOCG00000011284.1|UniProtKB=W5MZQ7 W5MZQ7 PTHR45941:SF1 ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2-LIKE-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;multicellular organismal-level homeostasis#GO:0048871;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;biological process involved in interspecies interaction between organisms#GO:0044419;homeostatic process#GO:0042592;homeostasis of number of cells#GO:0048872;oligosaccharide biosynthetic process#GO:0009312;protein metabolic process#GO:0019538 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004714.1|UniProtKB=W5MBA3 W5MBA3 PTHR45889:SF2 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 1 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of natural killer cell mediated immunity#GO:0002715;regulation of leukocyte mediated immunity#GO:0002703;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of response to biotic stimulus#GO:0002831;regulation of defense response#GO:0031347;cell recognition#GO:0008037;regulation of immune response#GO:0050776;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;detection of stimulus#GO:0051606;homophilic cell-cell adhesion#GO:0007156;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of lymphocyte mediated immunity#GO:0002706;regulation of cell killing#GO:0031341;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103 cell junction#GO:0030054;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000017445.1|UniProtKB=W5NLP1 W5NLP1 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN LOW QUALITY PROTEIN: ODORANT RECEPTOR 125-6-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011765.1|UniProtKB=W5N1H4 W5N1H4 PTHR10502:SF19 ANNEXIN ANNEXIN A6 ion binding#GO:0043167;phospholipid binding#GO:0005543;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 metal ion transport#GO:0030001;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;mitochondrial calcium ion homeostasis#GO:0051560;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;biological regulation#GO:0065007;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;apoptotic signaling pathway#GO:0097190;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;signaling#GO:0023052;response to stimulus#GO:0050896;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;cellular process#GO:0009987;signal transduction#GO:0007165;monoatomic ion homeostasis#GO:0050801;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;chemical homeostasis#GO:0048878 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000005408.1|UniProtKB=W5MDV6 W5MDV6 PTHR10730:SF5 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE 1 dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013379.1|UniProtKB=W5N780 W5N780 PTHR23268:SF31 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 30 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002927.1|UniProtKB=W5M4Y6 W5M4Y6 GMPR PTHR43170:SF3 GMP REDUCTASE GMP REDUCTASE 1 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007295.1|UniProtKB=W5MKC8 W5MKC8 PTHR19944:SF86 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488;protein-containing complex binding#GO:0044877 regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;positive regulation of leukocyte activation#GO:0002696;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of cell adhesion#GO:0045785;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037 late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000018011.1|UniProtKB=W5NNA3 W5NNA3 PTHR24247:SF33 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1E G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000012604.1|UniProtKB=W5N4F5 W5N4F5 PTHR10707:SF13 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;oxidoreductase complex#GO:1990204;membrane#GO:0016020;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;transporter complex#GO:1990351;organelle membrane#GO:0031090 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000006978.1|UniProtKB=W5MJ96 W5MJ96 PTHR23338:SF17 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;spliceosomal snRNP assembly#GO:0000387 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;cytoplasm#GO:0005737;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000002530.1|UniProtKB=W5M3M7 W5M3M7 PTHR11544:SF143 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014627.1|UniProtKB=W5NBJ5 W5NBJ5 PTHR31058:SF2 ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell differentiation#GO:0045597;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of neuron differentiation#GO:0045664;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000010738.1|UniProtKB=W5MXP9 W5MXP9 PTHR24342:SF6 SERINE/THREONINE-PROTEIN KINASE 17 SERINE_THREONINE-PROTEIN KINASE 17A protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012053.1|UniProtKB=W5N2H0 W5N2H0 PTHR47966:SF24 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED RENIN aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 circulatory system process#GO:0003013;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;metabolic process#GO:0008152;system process#GO:0003008;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;peptide hormone processing#GO:0016486;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;biosynthetic process#GO:0009058;biological regulation#GO:0065007;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;hormone metabolic process#GO:0042445;blood circulation#GO:0008015 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;aspartic protease#PC00053 LEPOC|Ensembl=ENSLOCG00000000284.1|UniProtKB=W5LW06 W5LW06 PTHR10352:SF13 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 1 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;RNA stabilization#GO:0043489;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;positive regulation of biosynthetic process#GO:0009891;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 CCKR signaling map#P06959>HuR#G07273;CCKR signaling map#P06959>HuR#P07211;CCKR signaling map#P06959>HuR#G06980 LEPOC|Ensembl=ENSLOCG00000018308.1|UniProtKB=W5NP50 W5NP50 PTHR24028:SF241 CADHERIN-87A PROTOCADHERIN 2 ALPHA A 1 PRECURSOR cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000005032.1|UniProtKB=W5MCF4 W5MCF4 PTHR43807:SF6 FI04487P KYNURENINE--OXOGLUTARATE TRANSAMINASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000003527.1|UniProtKB=W5M737 W5M737 PTHR11584:SF363 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 15 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674 signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;p38MAPK cascade#GO:0038066;response to stimulus#GO:0050896;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005941.1|UniProtKB=W5MFL8 W5MFL8 PTHR14360:SF14 PROTEIN FMP32, MITOCHONDRIAL COILED-COIL DOMAIN-CONTAINING PROTEIN 90B, MITOCHONDRIAL intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000722.1|UniProtKB=W5LXG2 W5LXG2 PTHR16484:SF10 PARTITIONING DEFECTIVE 3 RELATED PARTITIONING DEFECTIVE 3 HOMOLOG ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;binding#GO:0005488 cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;localization#GO:0051179;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;microtubule cytoskeleton organization#GO:0000226;establishment of cell polarity#GO:0030010;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010 cell periphery#GO:0071944;cell cortex#GO:0005938;cell-cell junction#GO:0005911;membrane#GO:0016020;apical plasma membrane#GO:0016324;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;apical part of cell#GO:0045177;apical junction complex#GO:0043296;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000003243.1|UniProtKB=W5M620 W5M620 PTHR12419:SF101 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000010699.1|UniProtKB=W5MXJ7 W5MXJ7 PTHR10300:SF4 CALCIPRESSIN CALCIPRESSIN-1 molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000000271.1|UniProtKB=W5LVY7 W5LVY7 PTHR24393:SF190 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 13 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013897.1|UniProtKB=W5N932 W5N932 PTHR13703:SF53 SMAD SMAD FAMILY MEMBER 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;response to transforming growth factor beta#GO:0071559;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;positive regulation of RNA metabolic process#GO:0051254;BMP signaling pathway#GO:0030509;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;developmental process#GO:0032502;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to growth factor stimulus#GO:0071363;activin receptor signaling pathway#GO:0032924;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;positive regulation of macromolecule metabolic process#GO:0010604;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 LEPOC|Ensembl=ENSLOCG00000001575.1|UniProtKB=W5M0A2 W5M0A2 PTHR46078:SF2 FORKHEAD BOX PROTEIN J2 FAMILY MEMBER FORK-HEAD DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000010807.1|UniProtKB=W5MY00 W5MY00 PTHR11905:SF13 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 23 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 synaptic membrane#GO:0097060;cell junction#GO:0030054;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000001668.1|UniProtKB=W5M0R9 W5M0R9 PTHR24020:SF86 COLLAGEN ALPHA COLLAGEN TYPE VI ALPHA 6 CHAIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000017477.1|UniProtKB=W5NLS3 W5NLS3 PTHR31046:SF0 TRANSMEMBRANE PROTEIN 121 TRANSMEMBRANE PROTEIN 121 LEPOC|Ensembl=ENSLOCG00000017324.1|UniProtKB=W5NLC0 W5NLC0 PTHR11589:SF3 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIC FACTOR BDNF PRECURSOR FORM growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of apoptotic process#GO:0043066;multicellular organismal process#GO:0032501;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to stimulus#GO:0051716;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular response to nerve growth factor stimulus#GO:1990090;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;neuron projection development#GO:0031175;regulation of neuron apoptotic process#GO:0043523;negative regulation of neuron apoptotic process#GO:0043524;nervous system development#GO:0007399;regulation of trans-synaptic signaling#GO:0099177;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;neuron development#GO:0048666;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of programmed cell death#GO:0043067;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902 cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle#GO:0030133;presynapse#GO:0098793;secretory vesicle#GO:0099503;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 neurotrophic factor#PC00163;growth factor#PC00112 Metabotropic glutamate receptor group II pathway#P00040>BDNF#G01540;Huntington disease#P00029>BDNF#G01531;Huntington disease#P00029>BDNF#P00795 LEPOC|Ensembl=ENSLOCG00000017208.1|UniProtKB=W5NKW6 W5NKW6 PTHR23004:SF9 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2C microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000001781.1|UniProtKB=W5M106 W5M106 PTHR10631:SF1 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRNA (GUANINE(27)-N(2))-DIMETHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000004187.1|UniProtKB=W5M9D6 W5M9D6 PTHR21402:SF15 GAMETOCYTE SPECIFIC FACTOR 1-RELATED U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000012977.1|UniProtKB=W5N5S5 W5N5S5 PTHR11461:SF191 SERINE PROTEASE INHIBITOR, SERPIN PROTEIN Z-DEPENDENT PROTEASE INHIBITOR enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Blood coagulation#P00011>ZPI#P00425 LEPOC|Ensembl=ENSLOCG00000008995.1|UniProtKB=W5MRH2 W5MRH2 PTHR11977:SF35 VILLIN VILLIN-1 ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;phosphatidylinositol phosphate binding#GO:1901981 regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of anatomical structure size#GO:0090066;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament depolymerization#GO:0030834;regulation of developmental process#GO:0050793;actin filament-based process#GO:0030029;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;organelle#GO:0043226;actin cytoskeleton#GO:0015629;cell leading edge#GO:0031252;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000008967.1|UniProtKB=W5MRB4 W5MRB4 PTHR47678:SF2 TETRATRICOPEPTIDE REPEAT PROTEIN 31 TETRATRICOPEPTIDE REPEAT DOMAIN 31 LEPOC|Ensembl=ENSLOCG00000007807.1|UniProtKB=W5MM90 W5MM90 PTHR24006:SF655 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012094.1|UniProtKB=W5N2M7 W5N2M7 PTHR23239:SF367 INTERMEDIATE FILAMENT KERATIN 15-RELATED structural molecule activity#GO:0005198 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;morphogenesis of an epithelium#GO:0002009;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;anatomical structure morphogenesis#GO:0009653;tissue development#GO:0009888;epithelium development#GO:0060429 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000004160.1|UniProtKB=W5M9C2 W5M9C2 PTHR12849:SF0 RNA LARIAT DEBRANCHING ENZYME LARIAT DEBRANCHING ENZYME nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound catabolic process#GO:0034655;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000009040.1|UniProtKB=W5MRL8 W5MRL8 PTHR12187:SF3 AGAP000124-PA INOSITOL POLYPHOSPHATE 4-PHOSPHATASE TYPE II catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000014911.1|UniProtKB=W5NCK4 W5NCK4 PTHR12474:SF1 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN 3 oxidoreductase activity#GO:0016491;amino acid binding#GO:0016597;catalytic activity#GO:0003824;cation binding#GO:0043169;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;binding#GO:0005488 regulation of macroautophagy#GO:0016241;negative regulation of TORC1 signaling#GO:1904262;cellular response to amino acid starvation#GO:0034198;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;positive regulation of macroautophagy#GO:0016239;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to nitrogen compound#GO:1901699;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000005167.1|UniProtKB=W5MCW6 W5MCW6 PTHR21538:SF28 ANILLIN/RHOTEKIN RTKN RHOTEKIN 2B-RELATED cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actomyosin contractile ring assembly#GO:0000915;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;septin cytoskeleton organization#GO:0032185;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cell division#GO:0051301;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;septin ring organization#GO:0031106;cortical actin cytoskeleton organization#GO:0030866;cytoskeleton-dependent cytokinesis#GO:0061640 cell periphery#GO:0071944;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;contractile ring#GO:0070938;actomyosin contractile ring#GO:0005826;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000003880.1|UniProtKB=W5M8B6 W5M8B6 PTHR24208:SF91 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011921.1|UniProtKB=W5N1Z6 W5N1Z6 PTHR31594:SF19 AIG1-TYPE G DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000002904.1|UniProtKB=W5M4V3 W5M4V3 PTHR46963:SF1 SIMILAR TO RIKEN CDNA E130308A19 KIAA1958 HOMOLOG LEPOC|Ensembl=ENSLOCG00000017933.1|UniProtKB=W5NN27 W5NN27 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001156.1|UniProtKB=W5LYY3 W5LYY3 MMP1 PTHR10201:SF165 MATRIX METALLOPROTEINASE COLLAGENASE 3 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Plasminogen activating cascade#P00050>pro-MMP-13#P01254;Plasminogen activating cascade#P00050>MMP-13#P01250 LEPOC|Ensembl=ENSLOCG00000003285.1|UniProtKB=W5M687 W5M687 PTHR12610:SF22 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000012139.1|UniProtKB=W5N2S8 W5N2S8 PTHR11532:SF80 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE N CATALYTIC CHAIN carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015596.1|UniProtKB=W5NEZ4 W5NEZ4 PTHR24064:SF33 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 7 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;lipid localization#GO:0010876;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;fatty acid transport#GO:0015908;localization#GO:0051179;monocarboxylic acid transport#GO:0015718 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000018346.1|UniProtKB=W5NP88 W5NP88 PTHR16703:SF3 CLAUDIN-12 CLAUDIN-12 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000017147.1|UniProtKB=W5NKN2 W5NKN2 PTHR45617:SF166 LEUCINE RICH REPEAT FAMILY PROTEIN LRRNT DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010331.1|UniProtKB=W5MW98 W5MW98 PTHR11949:SF3 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000009152.1|UniProtKB=W5MS00 W5MS00 PTHR10003:SF112 SUPEROXIDE DISMUTASE CU-ZN -RELATED SUPEROXIDE DISMUTASE [CU-ZN] ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;antioxidant activity#GO:0016209;copper ion binding#GO:0005507;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;cellular oxidant detoxification#GO:0098869;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;superoxide metabolic process#GO:0006801 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;microbody#GO:0042579;mitochondrion#GO:0005739;peroxisome#GO:0005777;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016566.1|UniProtKB=W5NIK1 W5NIK1 PTHR24299:SF11 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1B1 oxidoreductase activity#GO:0016491;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 lipid catabolic process#GO:0016042;cellular process#GO:0009987;hormone metabolic process#GO:0042445;response to chemical#GO:0042221;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;cellular response to xenobiotic stimulus#GO:0071466;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;secondary metabolic process#GO:0019748;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;xenobiotic metabolic process#GO:0006805;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008;steroid catabolic process#GO:0006706 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012092.1|UniProtKB=W5N2M0 W5N2M0 PTHR28495:SF1 HYPOTHETICAL PROTEIN LOC100359752 GENE, 17266-RELATED gonad development#GO:0008406;multicellular organismal process#GO:0032501;male gonad development#GO:0008584;sex differentiation#GO:0007548;multicellular organism development#GO:0007275;animal organ development#GO:0048513;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;male sex differentiation#GO:0046661;development of primary male sexual characteristics#GO:0046546;reproductive process#GO:0022414;reproductive structure development#GO:0048608;developmental process involved in reproduction#GO:0003006;system development#GO:0048731;reproductive system development#GO:0061458;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 LEPOC|Ensembl=ENSLOCG00000003608.1|UniProtKB=W5M7C0 W5M7C0 PTHR23316:SF7 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-3 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005487.1|UniProtKB=W5ME10 W5ME10 PTHR15439:SF0 RETINOBLASTOMA-BINDING PROTEIN 6 E3 UBIQUITIN-PROTEIN LIGASE RBBP6 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003852.1|UniProtKB=W5M894 W5M894 PTHR15337:SF10 ANTERIOR GRADIENT PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 12 disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000010059.1|UniProtKB=W5MVA5 W5MVA5 PTHR13976:SF37 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED EPITHELIAL SPLICING REGULATORY PROTEIN 1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000010152.1|UniProtKB=W5MVM1 W5MVM1 PTHR47131:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3 voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 male gamete generation#GO:0048232;developmental maturation#GO:0021700;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;cell maturation#GO:0048469;flagellated sperm motility#GO:0030317;transport#GO:0006810;spermatogenesis#GO:0007283;developmental process#GO:0032502;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;metal ion transport#GO:0030001;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;anatomical structure development#GO:0048856;monoatomic cation transport#GO:0006812;localization#GO:0051179;multicellular organismal reproductive process#GO:0048609;spermatid development#GO:0007286;sexual reproduction#GO:0019953;sperm capacitation#GO:0048240;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;microtubule-based process#GO:0007017;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;sperm motility#GO:0097722;sodium ion transport#GO:0006814;cilium-dependent cell motility#GO:0060285;monoatomic ion transport#GO:0006811;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;voltage-gated calcium channel complex#GO:0005891;vesicle#GO:0031982;calcium channel complex#GO:0034704;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;monoatomic ion channel complex#GO:0034702;CatSper complex#GO:0036128;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;transporter complex#GO:1990351;cation channel complex#GO:0034703 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000000534.1|UniProtKB=W5LWT2 W5LWT2 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016758.1|UniProtKB=W5NJB0 W5NJB0 PTHR42693:SF11 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE A hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002554.1|UniProtKB=W5M3N7 W5M3N7 PTHR11592:SF7 GLUTATHIONE PEROXIDASE PROTEIN PEROXIDASE GPX8 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599 peroxidase#PC00180;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006104.1|UniProtKB=W5MG65 W5MG65 PTHR12638:SF0 PROTEIN MAGO NASHI HOMOLOG MAGO HOMOLOG, EXON JUNCTION COMPLEX SUBUNIT-RELATED negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nuclear mRNA surveillance#GO:0071028;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009521.1|UniProtKB=W5MTE0 W5MTE0 PTHR24023:SF912 COLLAGEN ALPHA COLLAGEN ALPHA-1(XV) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000008851.1|UniProtKB=W5MQV9 W5MQV9 PTHR10165:SF94 LIPID PHOSPHATE PHOSPHATASE PHOSPHATIDIC ACID PHOSPHATASE TYPE 2D phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 signaling#GO:0023052;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;dephosphorylation#GO:0016311;cell communication#GO:0007154;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000005373.1|UniProtKB=W5MDM2 W5MDM2 PTHR24322:SF747 PKSB EPIDERMAL RETINOL DEHYDROGENASE 2-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000014378.1|UniProtKB=W5NAP4 W5NAP4 PTHR15583:SF17 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR D ISOFORM X1 cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010678.1|UniProtKB=W5MXH2 W5MXH2 PTHR15508:SF4 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE-LIKE 1 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142 LEPOC|Ensembl=ENSLOCG00000006653.1|UniProtKB=W5MI24 W5MI24 PTHR15272:SF0 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;nucleosome organization#GO:0034728;protein-containing complex organization#GO:0043933 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000002066.1|UniProtKB=W5M202 W5M202 PTHR45851:SF5 MYC PROTO-ONCOGENE PROTEIN L-MYC-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000000020.1|UniProtKB=W5LV65 W5LV65 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013246.1|UniProtKB=W5N6Q6 W5N6Q6 PTHR24225:SF78 CHEMOTACTIC RECEPTOR PROSTAGLANDIN D2 RECEPTOR 2-LIKE molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;immune response-activating signaling pathway#GO:0002757;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of biological quality#GO:0065008;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018027.1|UniProtKB=W5NNB9 W5NNB9 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H6 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017510.1|UniProtKB=W5NLV6 W5NLV6 PTHR11984:SF6 CONNEXIN GAP JUNCTION GAMMA-1 PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 cell communication#GO:0007154;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000001522.1|UniProtKB=W5M044 W5M044 PTHR11742:SF55 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000846.1|UniProtKB=W5LXU2 W5LXU2 PTHR11200:SF117 INOSITOL 5-PHOSPHATASE INOSITOL POLYPHOSPHATE 5-PHOSPHATASE K hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;negative regulation of metabolic process#GO:0009892;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of polysaccharide metabolic process#GO:0032881;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;regulation of carbohydrate metabolic process#GO:0006109;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of glycogen biosynthetic process#GO:0005979;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;ruffle#GO:0001726;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000007874.1|UniProtKB=W5MMF2 W5MMF2 PTHR45716:SF6 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 5 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;exocytosis#GO:0006887;secretion by cell#GO:0032940;transport#GO:0006810 transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000011710.1|UniProtKB=W5N184 W5N184 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 lipid localization#GO:0010876;localization#GO:0051179;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;lipid transport#GO:0006869 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000009813.1|UniProtKB=W5MUE4 W5MUE4 PTHR13817:SF190 TITIN CONTACTIN 4 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000017401.1|UniProtKB=W5NLJ7 W5NLJ7 PTHR26451:SF928 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G PROTEIN-COUPLED RECEPTOR 148-RELATED binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017641.1|UniProtKB=W5NM87 W5NM87 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005604.1|UniProtKB=W5MEF5 W5MEF5 PTHR24014:SF4 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009377.1|UniProtKB=W5MSS8 W5MSS8 PTHR22089:SF2 MIRROR-IMAGE POLYDACTYLY GENE 1 PROTEIN MIRROR-IMAGE POLYDACTYLY GENE 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000011573.1|UniProtKB=W5N0R1 W5N0R1 PTHR22599:SF63 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 1B molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;hippo signaling#GO:0035329;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000013142.1|UniProtKB=W5N6C7 W5N6C7 PTHR10605:SF78 HEPARAN SULFATE SULFOTRANSFERASE SULFOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000010450.1|UniProtKB=W5MWS7 W5MWS7 PTHR23220:SF5 INTEGRIN ALPHA INTEGRIN ALPHA-8 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell surface receptor signaling pathway#GO:0007166;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Collagen#P00922;Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000004109.1|UniProtKB=W5M961 W5M961 PTHR24056:SF598 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;G2/M transition of mitotic cell cycle#GO:0000086;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;signaling#GO:0023052;mitotic cell cycle phase transition#GO:0044772;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;cell cycle G2/M phase transition#GO:0044839;biological regulation#GO:0065007;mitotic cell cycle process#GO:1903047 serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway feedback loops 2#P04398>cdk2#P04653;p53 pathway#P00059>Cdk2#P04625;p53 pathway#P00059>Cdc2#P04634 LEPOC|Ensembl=ENSLOCG00000001914.1|UniProtKB=W5M1H1 W5M1H1 PTHR13234:SF81 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosome#GO:0005764 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000016747.1|UniProtKB=W5NJ90 W5NJ90 PTHR14470:SF2 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 4 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003991.1|UniProtKB=W5M8R5 W5M8R5 PTHR45668:SF2 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 2 Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072;binding#GO:0005488;protein binding#GO:0005515 negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000001746.1|UniProtKB=W5M0V6 W5M0V6 PTHR14198:SF18 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 1 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000018153.1|UniProtKB=W5NNP5 W5NNP5 PTHR46048:SF13 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012346.1|UniProtKB=W5N3J5 W5N3J5 PTHR45620:SF22 PDF RECEPTOR-LIKE PROTEIN-RELATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000838.1|UniProtKB=W5LXU8 W5LXU8 PTHR24006:SF960 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 25 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004801.1|UniProtKB=W5MBK3 W5MBK3 PTHR11636:SF6 POU DOMAIN POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007827.1|UniProtKB=W5MM94 W5MM94 PTHR11442:SF7 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT BETA-RELATED molecular carrier activity#GO:0140104;binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 cellular process#GO:0009987;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;homeostatic process#GO:0042592;cell development#GO:0048468;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;localization#GO:0051179;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;globin#PC00107 LEPOC|Ensembl=ENSLOCG00000007293.1|UniProtKB=W5MKC6 W5MKC6 PTHR24099:SF23 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE MIDLINE-1 biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of microtubule-based process#GO:0032886 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010996.1|UniProtKB=W5MYP7 W5MYP7 PTHR10316:SF10 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of protein localization to membrane#GO:1905475;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;cell communication#GO:0007154 cytoplasm#GO:0005737;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell-cell junction#GO:0005911;adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000008759.1|UniProtKB=W5MQK2 W5MQK2 PTHR42883:SF2 GLUCOSE-1-PHOSPHATE THYMIDYLTRANSFERASE NUCLEOTIDYL TRANSFERASE DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;nucleotidyltransferase#PC00174 O-antigen biosynthesis#P02757>dTDP-glucose pyrophosphorylase#P03046 LEPOC|Ensembl=ENSLOCG00000007789.1|UniProtKB=W5MM47 W5MM47 PTHR45871:SF1 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000000627.1|UniProtKB=W5LX36 W5LX36 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011719.1|UniProtKB=W5N194 W5N194 PTHR18821:SF7 PROKINETICIN PROKINETICIN-1 cellular process#GO:0009987;cell population proliferation#GO:0008283;epithelial cell proliferation#GO:0050673;endothelial cell proliferation#GO:0001935 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000003457.1|UniProtKB=W5M6U3 W5M6U3 PTHR10502:SF100 ANNEXIN ANNEXIN A10 ion binding#GO:0043167;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000013961.1|UniProtKB=W5N9A1 W5N9A1 PTHR15151:SF20 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 12 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 apoptotic signaling pathway#GO:0097190;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;cell communication#GO:0007154;immune system process#GO:0002376;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052;programmed cell death#GO:0012501;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007227.1|UniProtKB=W5MK47 W5MK47 PTHR12687:SF4 NUCLEOLAR COMPLEX 2 AND RAD4-RELATED NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000872.1|UniProtKB=W5LXW8 W5LXW8 PTHR11630:SF73 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM6 catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;DNA repair#GO:0006281;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;MCM complex#GO:0042555;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014726.1|UniProtKB=W5NBW9 W5NBW9 PTHR10740:SF15 TRANSFORMING GROWTH FACTOR ALPHA PRO-NEUREGULIN-4, MEMBRANE-BOUND ISOFORM signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 positive regulation of cellular component organization#GO:0051130;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of mitotic nuclear division#GO:0045840;cell surface receptor signaling pathway#GO:0007166;regulation of mitotic nuclear division#GO:0007088;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;positive regulation of cell cycle#GO:0045787;epidermal growth factor receptor signaling pathway#GO:0007173 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000018251.1|UniProtKB=W5NNZ3 W5NNZ3 PTHR19290:SF99 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED TRANSCRIPTION FACTOR ATOH7 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;neuron fate commitment#GO:0048663;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cell fate commitment#GO:0045165;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000003103.1|UniProtKB=W5M5J5 W5M5J5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000012143.1|UniProtKB=W5N2S9 W5N2S9 PTHR12170:SF6 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE RMND5B catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000010013.1|UniProtKB=W5MV37 W5MV37 PTHR16083:SF95 LEUCINE RICH REPEAT CONTAINING PROTEIN RAS SUPPRESSOR PROTEIN 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002829.1|UniProtKB=W5M4M0 W5M4M0 PTHR24329:SF322 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARISTALESS-LIKE 4 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007334.1|UniProtKB=W5MKH3 W5MKH3 PTHR11348:SF4 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 4 integrin binding#GO:0005178;cell adhesion molecule binding#GO:0050839;heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;glycosaminoglycan binding#GO:0005539 cell communication#GO:0007154;cell adhesion#GO:0007155;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000007826.1|UniProtKB=W5MM93 W5MM93 PTHR13693:SF50 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE, NON-SPECIFIC, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;macromolecule metabolic process#GO:0043170;porphyrin-containing compound biosynthetic process#GO:0006779;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transaminase#PC00216 LEPOC|Ensembl=ENSLOCG00000011504.1|UniProtKB=W5N0J2 W5N0J2 PTHR11528:SF122 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-ALPHA 1 purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887 response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;protein folding#GO:0006457;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;cellular response to heat#GO:0034605;response to heat#GO:0009408;response to stress#GO:0006950;regulation of protein stability#GO:0031647;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein stabilization#GO:0050821 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;cell body#GO:0044297;myelin sheath#GO:0043209;perinuclear region of cytoplasm#GO:0048471;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634 chaperone#PC00072;Hsp90 family chaperone#PC00028 LEPOC|Ensembl=ENSLOCG00000002347.1|UniProtKB=W5M2Z2 W5M2Z2 PTHR25465:SF32 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010880.1|UniProtKB=W5MY73 W5MY73 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014460.1|UniProtKB=W5NAZ0 W5NAZ0 PTHR12226:SF5 MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;oligosaccharide biosynthetic process#GO:0009312;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051 LEPOC|Ensembl=ENSLOCG00000008986.1|UniProtKB=W5MRH7 W5MRH7 PTHR24023:SF1128 COLLAGEN ALPHA COLLAGEN ALPHA-6(IV) CHAIN ISOFORM X1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000004271.1|UniProtKB=W5M9P7 W5M9P7 PTHR25462:SF310 BONUS, ISOFORM C-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 59 ISOFORM X1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000000061.1|UniProtKB=W5LVB4 W5LVB4 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006462.1|UniProtKB=W5MHF0 W5MHF0 PTHR10972:SF53 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 1 steroid binding#GO:0005496;cholesterol binding#GO:0015485;lipid binding#GO:0008289;alcohol binding#GO:0043178;sterol binding#GO:0032934;small molecule binding#GO:0036094;binding#GO:0005488 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000014971.1|UniProtKB=W5NCS5 W5NCS5 PTHR10937:SF12 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 1 transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740 UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 transaminase#PC00216 O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051;N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042 LEPOC|Ensembl=ENSLOCG00000012563.1|UniProtKB=W5N4D4 W5N4D4 PTHR24026:SF32 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 2 animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron projection development#GO:0031175;axon development#GO:0061564;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell-cell junction#GO:0005911 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000012370.1|UniProtKB=W5N3L7 W5N3L7 PTHR13902:SF114 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK4 transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;negative regulation of transport#GO:0051051;signaling#GO:0023052;homeostatic process#GO:0042592;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;chemical homeostasis#GO:0048878 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000002772.1|UniProtKB=W5M4F1 W5M4F1 PTHR48025:SF28 OS02G0815200 PROTEIN RRM DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000018322.1|UniProtKB=W5NP64 W5NP64 PTHR20961:SF167 GLYCOSYLTRANSFERASE PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2 acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006112.1|UniProtKB=W5MG74 W5MG74 PTHR11256:SF12 BCL-2 RELATED BCL-2-LIKE PROTEIN 1 channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;organelle organization#GO:0006996;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;programmed cell death#GO:0012501;cellular response to stimulus#GO:0051716;cell death#GO:0008219;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741 CCKR signaling map#P06959>BCL2L1#P07117;Apoptosis signaling pathway#P00006>Bcl-xL#P00257;Apoptosis signaling pathway#P00006>Bcl-xS#P00323 LEPOC|Ensembl=ENSLOCG00000010753.1|UniProtKB=W5MXR6 W5MXR6 PTHR45701:SF12 SYNAPTOBREVIN FAMILY MEMBER SI:CH73-234B20.5 protein binding#GO:0005515;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membrane fusion#GO:0061025;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;vesicle fusion#GO:0006906;regulation of body fluid levels#GO:0050878;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;secretion#GO:0046903;localization#GO:0051179 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005556.1|UniProtKB=W5ME98 W5ME98 PTHR28650:SF1 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN GPI ALPHA-1,4-MANNOSYLTRANSFERASE I, STABILIZING SUBUNIT LEPOC|Ensembl=ENSLOCG00000008151.1|UniProtKB=W5MND5 W5MND5 PTHR11627:SF2 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE B lyase activity#GO:0016829;fructose-bisphosphate aldolase activity#GO:0004332;aldehyde-lyase activity#GO:0016832;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 lyase#PC00144;aldolase#PC00044 Glycolysis#P00024>Aldolase#P00679;Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959 LEPOC|Ensembl=ENSLOCG00000009971.1|UniProtKB=W5MUY0 W5MUY0 PTHR36290:SF1 RIKEN CDNA D630039A03 GENE RIKEN CDNA D630039A03 GENE LEPOC|Ensembl=ENSLOCG00000014679.1|UniProtKB=W5NBR0 W5NBR0 PTHR12435:SF2 FAMILY NOT NAMED PROTEIN KTI12 HOMOLOG tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774 LEPOC|Ensembl=ENSLOCG00000000937.1|UniProtKB=W5LY38 W5LY38 PTHR10489:SF594 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 4 molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell migration#GO:0016477;brain development#GO:0007420;immune response#GO:0006955;calcium-mediated signaling#GO:0019722;neurogenesis#GO:0022008;response to external stimulus#GO:0009605;cellular developmental process#GO:0048869;developmental process#GO:0032502;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;system development#GO:0048731;cell chemotaxis#GO:0060326;anatomical structure development#GO:0048856;cell communication#GO:0007154;chemotaxis#GO:0006935;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;head development#GO:0060322;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;animal organ development#GO:0048513;multicellular organism development#GO:0007275;signaling#GO:0023052;response to stimulus#GO:0050896;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854;Axon guidance mediated by Slit/Robo#P00008>Cxcr4#P00351 LEPOC|Ensembl=ENSLOCG00000005093.1|UniProtKB=W5MCM6 W5MCM6 PTHR22847:SF626 WD40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 38 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000006420.1|UniProtKB=W5MH96 W5MH96 PTHR23067:SF8 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385B nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000015482.1|UniProtKB=W5NEJ7 W5NEJ7 PTHR45624:SF23 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL CARNITINE_ACYLCARNITINE CARRIER PROTEIN quaternary ammonium group transmembrane transporter activity#GO:0015651;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 mitochondrial transport#GO:0006839;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017224.1|UniProtKB=W5NKZ3 W5NKZ3 PTHR12353:SF3 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 2 regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;organelle#GO:0043226;cell junction#GO:0030054;postsynaptic specialization#GO:0099572 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012645.1|UniProtKB=W5N4K6 W5N4K6 PTHR48012:SF35 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 10 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000000447.1|UniProtKB=W5LWI1 W5LWI1 PTHR23266:SF403 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006306.1|UniProtKB=W5MGW4 W5MGW4 PTHR12877:SF15 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 17 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000000158.1|UniProtKB=W5LVP7 W5LVP7 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010251.1|UniProtKB=W5MVY6 W5MVY6 PTHR16768:SF7 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A PROTEIN FAM107B LEPOC|Ensembl=ENSLOCG00000015917.1|UniProtKB=W5NG40 W5NG40 PTHR24366:SF171 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC33 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000009664.1|UniProtKB=W5MTV5 W5MTV5 PTHR11819:SF96 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015628.1|UniProtKB=W5NF30 W5NF30 PTHR23117:SF18 GUANYLATE KINASE-RELATED LEUCINE-RICH REPEAT AND GUANYLATE KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular component organization or biogenesis#GO:0071840;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;microtubule-based process#GO:0007017;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;ribose phosphate biosynthetic process#GO:0046390;cell projection assembly#GO:0030031;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;cilium organization#GO:0044782;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;cell projection organization#GO:0030030;gamete generation#GO:0007276;cilium assembly#GO:0060271;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;nucleoside phosphate biosynthetic process#GO:1901293;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;spermatogenesis#GO:0007283;purine ribonucleoside diphosphate metabolic process#GO:0009179;male gamete generation#GO:0048232;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;plasma membrane bounded cell projection organization#GO:0120036;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;microtubule cytoskeleton organization#GO:0000226;organophosphate biosynthetic process#GO:0090407;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;nucleoside diphosphate metabolic process#GO:0009132;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;reproductive process#GO:0022414;nucleoside phosphate metabolic process#GO:0006753;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982 transferase#PC00220;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000006524.1|UniProtKB=W5MHM9 W5MHM9 PTHR15116:SF14 DNA-BINDING PROTEIN SATB FAMILY MEMBER DNA-BINDING PROTEIN SATB1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;Lambda repressor-like transcription factor#PC00245 LEPOC|Ensembl=ENSLOCG00000015423.1|UniProtKB=W5NEC1 W5NEC1 PTHR14399:SF4 P53-INDUCED PROTEIN RELATED P53 APOPTOSIS EFFECTOR RELATED TO PMP-22 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 p53 pathway#P00059>PERP#G01565 LEPOC|Ensembl=ENSLOCG00000013446.1|UniProtKB=W5N7H1 W5N7H1 PTHR14445:SF37 GRB10 INTERACTING GYF PROTEIN GRB10-INTERACTING GYF PROTEIN 1 translation regulator activity#GO:0045182 negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;insulin-like growth factor receptor signaling pathway#GO:0048009;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to stimulus#GO:0051716;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000008602.1|UniProtKB=W5MPZ6 W5MPZ6 PTHR11866:SF33 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E RECEPTOR 1C (SUBTYPE EP1) ISOFORM X1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016411.1|UniProtKB=W5NI11 W5NI11 PTHR22950:SF222 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 4 L-amino acid transmembrane transporter activity#GO:0015179;neutral L-amino acid transmembrane transporter activity#GO:0015175;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 amino acid transporter#PC00046;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014696.1|UniProtKB=W5NBT2 W5NBT2 PTHR46002:SF6 EG:114D9.1 PROTEIN-RELATED CALCINEURIN B HOMOLOGOUS PROTEIN 2 calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of calcium-mediated signaling#GO:0050848;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of calcium-mediated signaling#GO:0050850;positive regulation of signaling#GO:0023056;regulation of calcineurin-NFAT signaling cascade#GO:0070884;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010210.1|UniProtKB=W5MVU1 W5MVU1 PTHR12369:SF19 CHONDROITIN SYNTHASE CHONDROITIN SULFATE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000001157.1|UniProtKB=W5LYU8 W5LYU8 PTHR19957:SF3 SYNTAXIN SYNTAXIN-5 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 vesicle fusion#GO:0006906;cellular component organization#GO:0016043;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 SNARE protein#PC00034 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091 LEPOC|Ensembl=ENSLOCG00000014639.1|UniProtKB=W5NBL0 W5NBL0 PTHR14773:SF0 WD REPEAT-CONTAINING PROTEIN 76 WD REPEAT-CONTAINING PROTEIN 76 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of response to stress#GO:0080134;regulation of cellular response to stress#GO:0080135;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011447.1|UniProtKB=W5N0C0 W5N0C0 PTHR10241:SF20 LETHAL 2 GIANT LARVAE PROTEIN LLGL SCRIBBLE CELL POLARITY COMPLEX COMPONENT 2 syntaxin binding#GO:0019905;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;binding#GO:0005488;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;SNARE binding#GO:0000149;enzyme activator activity#GO:0008047 transport#GO:0006810;regulation of response to stimulus#GO:0048583;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;establishment of spindle localization#GO:0051293;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;localization within membrane#GO:0051668;actin filament-based process#GO:0030029;regulation of Notch signaling pathway#GO:0008593;organelle localization#GO:0051640;cortical cytoskeleton organization#GO:0030865;cortical actin cytoskeleton organization#GO:0030866;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;secretion#GO:0046903;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;regulation of cell communication#GO:0010646;Golgi to plasma membrane transport#GO:0006893;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;Golgi vesicle transport#GO:0048193;exocytosis#GO:0006887;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;cellular component organization or biogenesis#GO:0071840;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;regulation of establishment or maintenance of cell polarity#GO:0032878;vesicle-mediated transport#GO:0016192;regulation of signaling#GO:0023051;establishment or maintenance of cell polarity#GO:0007163;post-Golgi vesicle-mediated transport#GO:0006892;secretion by cell#GO:0032940;spindle localization#GO:0051653;cellular localization#GO:0051641;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cellular component organization#GO:0016043;export from cell#GO:0140352;establishment of organelle localization#GO:0051656 intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007625.1|UniProtKB=W5MLJ2 W5MLJ2 PTHR12253:SF46 RH14732P GROUP 3 SECRETORY PHOSPHOLIPASE A2-RELATED LEPOC|Ensembl=ENSLOCG00000013560.1|UniProtKB=W5N7V8 W5N7V8 LSM3 PTHR13110:SF0 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3 LSM3 HOMOLOG, U6 SMALL NUCLEAR RNA AND MRNA DEGRADATION ASSOCIATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;U4/U6 x U5 tri-snRNP complex#GO:0046540;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000007881.1|UniProtKB=W5MMG0 W5MMG0 PTHR45617:SF186 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009558.1|UniProtKB=W5MTH2 W5MTH2 PTHR48034:SF1 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG BETA nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007317.1|UniProtKB=W5MKF3 W5MKF3 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;binding#GO:0005488 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006234.1|UniProtKB=W5MGL7 W5MGL7 PTHR46333:SF3 CYTOKINESIS PROTEIN 3 KYPHOSCOLIOSIS PEPTIDASE synapse organization#GO:0050808;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;muscle organ development#GO:0007517;neuromuscular junction development#GO:0007528;animal organ development#GO:0048513;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;muscle structure development#GO:0061061;cell junction organization#GO:0034330 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010292.1|UniProtKB=W5MW54 W5MW54 PTHR10887:SF322 DNA2/NAM7 HELICASE FAMILY RNA HELICASE MOV-10 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194 intracellular organelle#GO:0043229;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cytosol#GO:0005829;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000004329.1|UniProtKB=W5M9X6 W5M9X6 PTHR43591:SF101 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase#PC00155;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007437.1|UniProtKB=W5MKW3 W5MKW3 PTHR11753:SF19 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150;vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000015342.1|UniProtKB=W5NE19 W5NE19 PTHR11848:SF39 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 10 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000008545.1|UniProtKB=W5MPU1 W5MPU1 PTHR10211:SF0 DEOXYRIBODIPYRIMIDINE PHOTOLYASE DEOXYRIBODIPYRIMIDINE PHOTO-LYASE catalytic activity, acting on DNA#GO:0140097;lyase activity#GO:0016829;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;deoxyribodipyrimidine photo-lyase activity#GO:0003904;carbon-carbon lyase activity#GO:0016830 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;pyrimidine dimer repair#GO:0006290;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;photoreactive repair#GO:0000719;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000015920.1|UniProtKB=W5NG42 W5NG42 PTHR13245:SF14 RRP15-LIKE PROTEIN RRP15-LIKE PROTEIN macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466 LEPOC|Ensembl=ENSLOCG00000013492.1|UniProtKB=W5N7M4 W5N7M4 PTHR15852:SF49 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN PROTEIN SSUH2 HOMOLOG LEPOC|Ensembl=ENSLOCG00000003384.1|UniProtKB=W5M6K1 W5M6K1 PTHR10125:SF12 P2X PURINOCEPTOR P2X PURINOCEPTOR 5 monoatomic cation channel activity#GO:0005261;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000006951.1|UniProtKB=W5MJ48 W5MJ48 PTHR21732:SF0 MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 4 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000005992.1|UniProtKB=W5MFT1 W5MFT1 PTHR24388:SF42 ZINC FINGER PROTEIN ZINC FINGER PROTEIN SNAI2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000003514.1|UniProtKB=W5M704 W5M704 PTHR11848:SF135 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 7 cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 response to endogenous stimulus#GO:0009719;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP7#G06687;Gonadotropin-releasing hormone receptor pathway#P06664>BMP7#G06901;Gonadotropin-releasing hormone receptor pathway#P06664>BMP6/7#P06752;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000008352.1|UniProtKB=W5MP40 W5MP40 PTHR42807:SF1 GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013496.1|UniProtKB=W5N7N4 W5N7N4 PTHR15852:SF11 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN SSU-2 HOMOLOG, TANDEM DUPLICATE 2-RELATED LEPOC|Ensembl=ENSLOCG00000016453.1|UniProtKB=W5NI64 W5NI64 PTHR10583:SF4 CHROMOGRANIN SECRETOGRANIN-1 secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000016855.1|UniProtKB=W5NJM7 W5NJM7 PTHR11616:SF280 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;amino acid transmembrane transporter activity#GO:0015171;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;amino acid transport#GO:0006865;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987 plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000008573.1|UniProtKB=W5MPW6 W5MPW6 PTHR11653:SF12 PARVALBUMIN ALPHA PARVALBUMIN metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000014714.1|UniProtKB=W5NBV9 W5NBV9 PTHR24240:SF17 OPSIN MEDIUM-WAVE-SENSITIVE OPSIN 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;biological regulation#GO:0065007;detection of stimulus#GO:0051606;signal transduction#GO:0007165;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007345.1|UniProtKB=W5MKM5 W5MKM5 PTHR47096:SF4 MISSHAPEN LIKE KINASE 1 NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000001216.1|UniProtKB=W5LZ17 W5LZ17 PTHR19850:SF28 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-4 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117;G-protein#PC00020;protein-binding activity modulator#PC00095 Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;GABA-B receptor II signaling#P05731>Gbeta#P05755;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Wnt signaling pathway#P00057>GBeta#P01457;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;PI3 kinase pathway#P00048>Gbetagamma#P01188;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Endogenous cannabinoid signaling#P05730>Gbeta#P05745 LEPOC|Ensembl=ENSLOCG00000011700.1|UniProtKB=W5N173 W5N173 PTHR10778:SF10 SOLUTE CARRIER FAMILY 35 MEMBER B SOLUTE CARRIER FAMILY 35 MEMBER B1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;organophosphate ester transmembrane transporter activity#GO:0015605;UDP-galactose transmembrane transporter activity#GO:0005459;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleotide-sugar transmembrane transport#GO:0015780 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000011564.1|UniProtKB=W5N0Q1 W5N0Q1 PTHR43888:SF59 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ (HSP40) HOMOLOG, SUBFAMILY A, MEMBER 1, LIKE protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515;ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to stress#GO:0006950;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular response to stress#GO:0033554;protein refolding#GO:0042026;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein folding#GO:0006457;response to stimulus#GO:0050896 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013346.1|UniProtKB=W5N748 W5N748 PTHR13723:SF281 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PAPILIN catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000015286.1|UniProtKB=W5NDU8 W5NDU8 PTHR12629:SF6 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 2-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;alcohol metabolic process#GO:0006066;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000011947.1|UniProtKB=W5N233 W5N233 PTHR24034:SF76 EGF-LIKE DOMAIN-CONTAINING PROTEIN COLLAGEN AND CALCIUM-BINDING EGF DOMAIN-CONTAINING PROTEIN 1 system development#GO:0048731;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;anatomical structure morphogenesis#GO:0009653 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000001542.1|UniProtKB=W5M062 W5M062 PTHR11819:SF145 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER 2 solute:sodium symporter activity#GO:0015370;carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;sugar transmembrane transporter activity#GO:0051119;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 renal system process#GO:0003014;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;multicellular organismal process#GO:0032501;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;transport#GO:0006810;carbohydrate transport#GO:0008643;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;renal absorption#GO:0070293;localization#GO:0051179;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000935.1|UniProtKB=W5LY79 W5LY79 PTHR14049:SF5 LEPRECAN 1 PROLYL 3-HYDROXYLASE 1 dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 metabolic process#GO:0008152;cellular process#GO:0009987 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000009736.1|UniProtKB=W5MU32 W5MU32 PTHR11834:SF7 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;hippo signaling#GO:0035329;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000018254.1|UniProtKB=W5NNZ6 W5NNZ6 PTHR24248:SF24 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2A ADRENERGIC RECEPTOR G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;hormone binding#GO:0042562;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 LEPOC|Ensembl=ENSLOCG00000003188.1|UniProtKB=W5M5W3 W5M5W3 PTHR21427:SF19 UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL lipid binding#GO:0008289;binding#GO:0005488 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000008871.1|UniProtKB=W5MQZ3 W5MQZ3 PTHR24238:SF79 G-PROTEIN COUPLED RECEPTOR GASTRIN_CHOLECYSTOKININ TYPE B RECEPTOR neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014769.1|UniProtKB=W5NC34 W5NC34 PTHR22957:SF320 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 8B enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096 multicellular organismal process#GO:0032501;system process#GO:0003008;renal system process#GO:0003014 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000001425.1|UniProtKB=W5LZS3 W5LZS3 PTHR19971:SF24 SIGNAL-REGULATORY PROTEIN BETA IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005060.1|UniProtKB=W5MCI3 W5MCI3 PTHR12002:SF115 CLAUDIN CLAUDIN 10-LIKE 2 ISOFORM X1 transporter activity#GO:0005215;paracellular tight junction channel activity#GO:0160187 cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;transport#GO:0006810;paracellular transport#GO:0160184;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell junction organization#GO:0034330 apical junction complex#GO:0043296;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000018102.1|UniProtKB=W5NNJ4 W5NNJ4 PTHR48050:SF31 STEROL 3-BETA-GLUCOSYLTRANSFERASE GLUCURONOSYLTRANSFERASE enzyme binding#GO:0019899;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme inhibitor activity#GO:0004857;catalytic activity#GO:0003824;transferase activity#GO:0016740;molecular function regulator activity#GO:0098772;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;cellular response to steroid hormone stimulus#GO:0071383;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;response to hormone#GO:0009725;steroid metabolic process#GO:0008202;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;estrogen metabolic process#GO:0008210;regulation of hormone levels#GO:0010817;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;liver development#GO:0001889;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;lipid metabolic process#GO:0006629;developmental process#GO:0032502;sterol metabolic process#GO:0016125;pigment metabolic process#GO:0042440;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;hormone metabolic process#GO:0042445;response to steroid hormone#GO:0048545;system development#GO:0048731;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000000774.1|UniProtKB=W5LXJ6 W5LXJ6 PTHR13237:SF9 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED NEUROGUIDIN ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774 organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014379.1|UniProtKB=W5NAP8 W5NAP8 PTHR13357:SF1 SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN NCK-INTERACTING PROTEIN WITH SH3 DOMAIN protein-containing complex binding#GO:0044877;binding#GO:0005488 transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;endocytosis#GO:0006897;localization#GO:0051179 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006043.1|UniProtKB=W5MFZ1 W5MFZ1 PTHR12396:SF12 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 3 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression, epigenetic#GO:0045814;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003855.1|UniProtKB=W5M893 W5M893 PTHR23037:SF7 CYTOKINE RECEPTOR INTERLEUKIN-21 RECEPTOR transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014875.1|UniProtKB=W5NCG1 W5NCG1 PTHR21308:SF2 PHYTANOYL-COA ALPHA-HYDROXYLASE ZGC:174917 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013813.1|UniProtKB=W5N8S6 W5N8S6 PTHR46303:SF2 VWFC DOMAIN-CONTAINING PROTEIN CHORDIN-LIKE PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515;cytokine binding#GO:0019955 negative regulation of BMP signaling pathway#GO:0030514;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000013577.1|UniProtKB=W5N7Y1 W5N7Y1 PTHR46232:SF1 SMARCE1 REGULATOR OF CHROMATIN SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1 DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;binding#GO:0005488 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000005014.1|UniProtKB=W5MCC8 W5MCC8 PTHR21257:SF57 DELTA(14)-STEROL REDUCTASE 7-DEHYDROCHOLESTEROL REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;secondary alcohol biosynthetic process#GO:1902653;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000013355.1|UniProtKB=W5N753 W5N753 PTHR19850:SF36 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-5 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor complex adaptor activity#GO:0030159 biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 protein-binding activity modulator#PC00095;heterotrimeric G-protein#PC00117;G-protein#PC00020 Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta5L#P00748;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;PI3 kinase pathway#P00048>Gbetagamma#P01188;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085 LEPOC|Ensembl=ENSLOCG00000017505.1|UniProtKB=W5NLV1 W5NLV1 PTHR10424:SF86 VIRAL ENVELOPE PROTEIN SYNCYTIN-A-LIKE myoblast fusion#GO:0007520;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;cell differentiation#GO:0030154;muscle structure development#GO:0061061;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;syncytium formation by cell-cell fusion#GO:0000768;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;striated muscle cell differentiation#GO:0051146 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000017299.1|UniProtKB=W5NL95 W5NL95 PTHR23049:SF10 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 11 myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 developmental process#GO:0032502;striated muscle tissue development#GO:0014706;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;muscle organ development#GO:0007517;muscle tissue development#GO:0060537;animal organ development#GO:0048513;anatomical structure development#GO:0048856;skeletal muscle tissue development#GO:0007519;tissue development#GO:0009888;muscle structure development#GO:0061061 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000005266.1|UniProtKB=W5MD86 W5MD86 PTHR13360:SF1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000013193.1|UniProtKB=W5N6J4 W5N6J4 PTHR11624:SF116 DEHYDROGENASE RELATED PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyruvate metabolic process#GO:0006090;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 transferase complex#GO:1990234;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;acetyltransferase complex#GO:1902493;protein-containing complex#GO:0032991 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005755.1|UniProtKB=W5MEZ3 W5MEZ3 PTHR45960:SF1 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 2 molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;receptor tyrosine kinase binding#GO:0030971;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;enzyme binding#GO:0019899 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Grb2#P01148;EGF receptor signaling pathway#P00018>Gab#P00563 LEPOC|Ensembl=ENSLOCG00000006052.1|UniProtKB=W5MFZ8 W5MFZ8 PTHR13337:SF2 SUCCINATE DEHYDROGENASE SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL tetrapyrrole binding#GO:0046906;binding#GO:0005488;small molecule binding#GO:0036094;heme binding#GO:0020037 mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099 membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005698.1|UniProtKB=W5MER8 W5MER8 PTHR24253:SF108 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016733.1|UniProtKB=W5NJ66 W5NJ66 PTHR15577:SF2 ZINC FINGER CONTAINING PROTEIN ZINC FINGER PROTEIN 318 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012545.1|UniProtKB=W5N4D0 W5N4D0 PTHR46399:SF9 B30.2/SPRY DOMAIN-CONTAINING PROTEIN RYANODINE RECEPTOR 3 gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261 calcium ion transmembrane transport#GO:0070588;muscle system process#GO:0003012;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;multicellular organismal process#GO:0032501;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;muscle contraction#GO:0006936;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;system process#GO:0003008 organelle subcompartment#GO:0031984;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;calcium channel complex#GO:0034704;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;sarcomere#GO:0030017;endoplasmic reticulum#GO:0005783;cation channel complex#GO:0034703;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;sarcoplasmic reticulum membrane#GO:0033017;supramolecular complex#GO:0099080;sarcoplasmic reticulum#GO:0016529;contractile muscle fiber#GO:0043292;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;sarcolemma#GO:0042383;I band#GO:0031674;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;endomembrane system#GO:0012505;Z disc#GO:0030018;cell periphery#GO:0071944;membrane#GO:0016020 CCKR signaling map#P06959>RYR1/2/3#P07088;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441;Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434 LEPOC|Ensembl=ENSLOCG00000006070.1|UniProtKB=W5MG20 W5MG20 PTHR20917:SF1 PNAS-RELATED CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000003605.1|UniProtKB=W5M7B4 W5M7B4 PTHR48067:SF1 GPI-ANCHOR TRANSAMIDASE GPI-ANCHOR TRANSAMIDASE hydrolase activity#GO:0016787;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;transferase activity#GO:0016740;catalytic activity#GO:0003824 gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;peptidase complex#GO:1905368;cytoplasm#GO:0005737;caspase complex#GO:0008303;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003765.1|UniProtKB=W5M807 W5M807 PTHR18884:SF115 SEPTIN SEPTIN hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;cell cortex#GO:0005938;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000009480.1|UniProtKB=W5MT74 W5MT74 PTHR23197:SF10 TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING TARGET OF NESH-SH3 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cellular process#GO:0009987;cell development#GO:0048468;tissue development#GO:0009888;cell differentiation#GO:0030154;mesenchymal cell differentiation#GO:0048762;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;mesenchyme development#GO:0060485;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;animal organ development#GO:0048513 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000005139.1|UniProtKB=W5MCT3 W5MCT3 PTHR46933:SF1 MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 2 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000002547.1|UniProtKB=W5M3N3 W5M3N3 PTHR45929:SF1 JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE SIGNAL TRANSDUCING ADAPTER MOLECULE 2 multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;macromolecule localization#GO:0033036;biological regulation#GO:0065007;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;protein localization to vacuole#GO:0072665;cell communication#GO:0007154;localization#GO:0051179;protein metabolic process#GO:0019538;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;signal transduction#GO:0007165;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;endosomal transport#GO:0016197;regulation of biological process#GO:0050789;late endosome to vacuole transport#GO:0045324;signaling#GO:0023052;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;response to stimulus#GO:0050896;establishment of protein localization to vacuole#GO:0072666;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein transport#GO:0015031;cellular localization#GO:0051641 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012999.1|UniProtKB=W5N5V0 W5N5V0 PTHR12665:SF11 ORMDL PROTEINS ORM1-LIKE PROTEIN 3 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;cellular process#GO:0009987;homeostatic process#GO:0042592 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000006693.1|UniProtKB=W5MI72 W5MI72 PTHR10151:SF65 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE 7 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002422.1|UniProtKB=W5M385 W5M385 PTHR23235:SF58 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002444.1|UniProtKB=W5M3A8 W5M3A8 PTHR24392:SF61 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR CTCF DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005158.1|UniProtKB=W5MCV5 W5MCV5 PTHR24086:SF48 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A FF1D-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;hormone-mediated signaling pathway#GO:0009755;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;tissue development#GO:0009888;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;response to hormone#GO:0009725;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014032.1|UniProtKB=W5N9K6 W5N9K6 PTHR13723:SF142 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 7 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;external encapsulating structure organization#GO:0045229;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000002050.1|UniProtKB=W5M1X0 W5M1X0 PTHR31435:SF9 PROTEIN NATD1 PROTEIN NATD1 LEPOC|Ensembl=ENSLOCG00000011535.1|UniProtKB=W5N0L3 W5N0L3 PTHR23310:SF53 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4 heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000013160.1|UniProtKB=W5N6F3 W5N6F3 PTHR10605:SF7 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 3B1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011874.1|UniProtKB=W5N1V1 W5N1V1 PTHR31915:SF15 SKICH DOMAIN-CONTAINING PROTEIN TAX1-BINDING PROTEIN 1 HOMOLOG B LEPOC|Ensembl=ENSLOCG00000003326.1|UniProtKB=W5M6C4 W5M6C4 PTHR24366:SF170 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS ELRR (EXTRACELLULAR LEUCINE-RICH REPEAT) ONLY immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000012368.1|UniProtKB=W5N3L3 W5N3L3 PTHR44252:SF3 D-ERYTHRULOSE REDUCTASE D-ERYTHRULOSE REDUCTASE-RELATED alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glucose metabolic process#GO:0006006 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015890.1|UniProtKB=W5NG08 W5NG08 PTHR46194:SF1 PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED LEPOC|Ensembl=ENSLOCG00000002689.1|UniProtKB=W5M462 W5M462 PTHR42861:SF23 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 2 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion homeostasis#GO:0055074;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000002452.1|UniProtKB=W5M3C4 W5M3C4 PTHR10492:SF108 FAMILY NOT NAMED ATP-DEPENDENT DNA HELICASE LEPOC|Ensembl=ENSLOCG00000017654.1|UniProtKB=W5NMA0 W5NMA0 PTHR26451:SF896 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005872.1|UniProtKB=W5MFD3 W5MFD3 PTHR11842:SF10 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000017100.1|UniProtKB=W5NKH1 W5NKH1 PTHR28524:SF3 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000000865.1|UniProtKB=W5LXV7 W5LXV7 PTHR12178:SF3 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 3 regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi cis cisterna#GO:0000137;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795 LEPOC|Ensembl=ENSLOCG00000010071.1|UniProtKB=W5MVB6 W5MVB6 PTHR15305:SF1 MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 LEPOC|Ensembl=ENSLOCG00000000983.1|UniProtKB=W5LY98 W5LY98 PTHR15546:SF2 BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN, 2A DDT DOMAIN-CONTAINING PROTEIN DDB_G0282237 LEPOC|Ensembl=ENSLOCG00000010372.1|UniProtKB=W5MWF7 W5MWF7 PTHR47958:SF89 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX20-RELATED catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618 protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;cellular anatomical structure#GO:0110165;SMN complex#GO:0032797;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000014806.1|UniProtKB=W5NC70 W5NC70 PTHR23235:SF21 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 13 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000014809.1|UniProtKB=W5NC73 W5NC73 PTHR11829:SF201 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-GAMMA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000003784.1|UniProtKB=W5M814 W5M814 PTHR46734:SF1 TELOMERIC REPEAT-BINDING FACTOR 1 TERF1 TELOMERIC REPEAT-BINDING FACTOR 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;telomerase activity#GO:0003720;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;RNA-directed DNA polymerase activity#GO:0003964;double-stranded DNA binding#GO:0003690 cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;organelle organization#GO:0006996;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;telomere maintenance via telomerase#GO:0007004;telomere maintenance via telomere lengthening#GO:0010833;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of chromosome organization#GO:2001251;telomere organization#GO:0032200;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;RNA-templated DNA biosynthetic process#GO:0006278;macromolecule metabolic process#GO:0043170;regulation of telomere maintenance#GO:0032204;chromosome organization#GO:0051276;telomere maintenance#GO:0000723 intracellular organelle#GO:0043229;nuclear telomere cap complex#GO:0000783;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000011323.1|UniProtKB=W5MZV2 W5MZV2 PTHR35077:SF2 SIMILAR TO AI661453 PROTEIN SIMILAR TO HUMAN CHROMOSOME 6 OPEN READING FRAME 132 LEPOC|Ensembl=ENSLOCG00000009185.1|UniProtKB=W5MS42 W5MS42 PTHR10489:SF930 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 1 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930 cellular process#GO:0009987;signal transduction#GO:0007165;granulocyte migration#GO:0097530;response to chemical#GO:0042221;neutrophil migration#GO:1990266;taxis#GO:0042330;intracellular signaling cassette#GO:0141124;neutrophil chemotaxis#GO:0030593;regulation of biological process#GO:0050789;granulocyte chemotaxis#GO:0071621;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;regulation of biological quality#GO:0065008;immune response#GO:0006955;cell migration#GO:0016477;biological regulation#GO:0065007;leukocyte migration#GO:0050900;leukocyte chemotaxis#GO:0030595;calcium-mediated signaling#GO:0019722;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;locomotion#GO:0040011;chemotaxis#GO:0006935;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008131.1|UniProtKB=W5MNB0 W5MNB0 PTHR24346:SF35 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE NIM1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004697.1|UniProtKB=W5MB69 W5MB69 PTHR14843:SF2 DEUBIQUITINATING PROTEIN VCIP135 DEUBIQUITINATING PROTEIN VCPIP1 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;endoplasmic reticulum membrane organization#GO:0090158;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;membrane organization#GO:0061024;nucleobase-containing compound metabolic process#GO:0006139;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;cellular response to stress#GO:0033554;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;Golgi organization#GO:0007030;endoplasmic reticulum organization#GO:0007029;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000015918.1|UniProtKB=W5NG41 W5NG41 PTHR12290:SF12 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 3 establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268 organelle membrane#GO:0031090;cell junction#GO:0030054;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum subcompartment#GO:0098827;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006778.1|UniProtKB=W5MIH6 W5MIH6 PTHR11955:SF97 FATTY ACID BINDING PROTEIN RETINOID-BINDING PROTEIN 7 organic acid binding#GO:0043177;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;lipid binding#GO:0008289;fatty acid binding#GO:0005504 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000011675.1|UniProtKB=W5N137 W5N137 PTHR45752:SF212 LEUCINE-RICH REPEAT-CONTAINING CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012409.1|UniProtKB=W5N3S0 W5N3S0 SMAD2 PTHR13703:SF42 SMAD SMAD FAMILY MEMBER 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;activin receptor signaling pathway#GO:0032924;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;positive regulation of RNA metabolic process#GO:0051254;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to transforming growth factor beta stimulus#GO:0071560;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;response to transforming growth factor beta#GO:0071559 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 LEPOC|Ensembl=ENSLOCG00000011643.1|UniProtKB=W5N0Z9 W5N0Z9 PTHR22948:SF73 TUDOR DOMAIN CONTAINING PROTEIN SERINE_THREONINE-PROTEIN KINASE 31 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011976.1|UniProtKB=W5N268 W5N268 PTHR13014:SF3 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S30/P52 PRO-APOTOTIC PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML65 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000005784.1|UniProtKB=W5MF30 W5MF30 PTHR24356:SF444 SERINE/THREONINE-PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;signaling#GO:0023052 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013256.1|UniProtKB=W5N6S2 W5N6S2 PTHR12886:SF0 PIG-M MANNOSYLTRANSFERASE GPI ALPHA-1,4-MANNOSYLTRANSFERASE I, CATALYTIC SUBUNIT hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mannosyltransferase complex#GO:0031501;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000007630.1|UniProtKB=W5MLK0 W5MLK0 PTHR23039:SF5 NANCE-HORAN SYNDROME PROTEIN ACTIN REMODELING REGULATOR NHS sensory system development#GO:0048880;multicellular organismal process#GO:0032501;visual system development#GO:0150063;camera-type eye development#GO:0043010;sensory organ development#GO:0007423;animal gross anatomical part developmental process#GO:0160108;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731;eye development#GO:0001654 LEPOC|Ensembl=ENSLOCG00000008249.1|UniProtKB=W5MNR2 W5MNR2 PTHR24115:SF458 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF13A ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;microtubule-based movement#GO:0007018;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;microtubule-based process#GO:0007017;protein transport#GO:0015031;intracellular protein localization#GO:0008104 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000007755.1|UniProtKB=W5MM06 W5MM06 PTHR21625:SF0 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX SUBUNIT 2 regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;cilium or flagellum-dependent cell motility#GO:0001539;microtubule cytoskeleton organization#GO:0000226;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;axoneme assembly#GO:0035082;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of microtubule-based movement#GO:0060632;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;membraneless organelle#GO:0043228;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001896.1|UniProtKB=W5M1E1 W5M1E1 PTHR45884:SF1 N-ACETYLTRANSFERASE ECO N-ACETYLTRANSFERASE ESCO1 acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic sister chromatid cohesion#GO:0007064;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000016445.1|UniProtKB=W5NI54 W5NI54 PTHR16160:SF12 FERMITIN 2-RELATED FERMITIN FAMILY HOMOLOG 1 signaling receptor binding#GO:0005102;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877 cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160 anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000017485.1|UniProtKB=W5NLT1 W5NLT1 PTHR22750:SF7 G-PROTEIN COUPLED RECEPTOR GLUCOSE-DEPENDENT INSULINOTROPIC RECEPTOR phospholipid binding#GO:0005543;phosphatidylcholine binding#GO:0031210;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;cation binding#GO:0043169 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007773.1|UniProtKB=W5MM29 W5MM29 PTHR12025:SF11 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR D cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of chemotaxis#GO:0050920;response to endogenous stimulus#GO:0009719;vascular endothelial growth factor receptor signaling pathway#GO:0048010;positive regulation of cell motility#GO:2000147;blood vessel morphogenesis#GO:0048514;response to abiotic stimulus#GO:0009628;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;angiogenesis#GO:0001525;cellular response to growth factor stimulus#GO:0071363;sprouting angiogenesis#GO:0002040;animal gross anatomical part developmental process#GO:0160108;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;positive regulation of response to external stimulus#GO:0032103;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cell surface receptor signaling pathway#GO:0007166;response to growth factor#GO:0070848;regulation of leukocyte migration#GO:0002685;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of chemotaxis#GO:0050921;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of locomotion#GO:0040017;response to hypoxia#GO:0001666;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014606.1|UniProtKB=W5NBG9 W5NBG9 PTHR12515:SF9 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED PROTEIN SMAUG HOMOLOG 2 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000013482.1|UniProtKB=W5N7L9 W5N7L9 PTHR19305:SF4 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 23 SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein binding#GO:0005515;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484 anterograde trans-synaptic signaling#GO:0098916;vesicle fusion#GO:0006906;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;membrane fusion#GO:0061025;synaptic vesicle membrane organization#GO:0048499;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;signaling#GO:0023052;export from cell#GO:0140352;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular localization#GO:0051641;secretion by cell#GO:0032940;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;vesicle fusion to plasma membrane#GO:0099500;regulated exocytosis#GO:0045055;exocytic process#GO:0140029 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034;membrane traffic protein#PC00150 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423 LEPOC|Ensembl=ENSLOCG00000012063.1|UniProtKB=W5N2I2 W5N2I2 PTHR10740:SF16 TRANSFORMING GROWTH FACTOR ALPHA AMPHIREGULIN protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083 enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of cellular component organization#GO:0051130;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of mitotic nuclear division#GO:0007088;cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of cell cycle#GO:0045787;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;ERBB signaling pathway#GO:0038127;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000009609.1|UniProtKB=W5MTP0 W5MTP0 PTHR46047:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 2 protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of MAPK cascade#GO:0043408;negative regulation of response to stimulus#GO:0048585;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000006615.1|UniProtKB=W5MHY3 W5MHY3 PTHR11360:SF158 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 9 monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009486.1|UniProtKB=W5MT78 W5MT78 PTHR46942:SF1 SIALIC ACID-BINDING IG-LIKE LECTIN 15 SIALIC ACID-BINDING IG-LIKE LECTIN 15 regulation of bone resorption#GO:0045124;regulation of hemopoiesis#GO:1903706;regulation of tissue remodeling#GO:0034103;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of multicellular organismal development#GO:2000026;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of actin filament-based process#GO:0032970;regulation of cell differentiation#GO:0045595;regulation of bone remodeling#GO:0046850;regulation of cell development#GO:0060284;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of multicellular organismal process#GO:0051239 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005700.1|UniProtKB=W5MES3 W5MES3 PTHR15111:SF2 RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3 UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1 enzyme inhibitor activity#GO:0004857;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of programmed cell death#GO:0043069;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of apoptotic process#GO:0042981;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003100.1|UniProtKB=W5M5L8 W5M5L8 PTHR46501:SF7 MYOMEGALIN CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2 ISOFORM X1 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cell cycle#GO:0007049;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000017718.1|UniProtKB=W5NMG4 W5NMG4 PTHR23268:SF28 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 27 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008145.1|UniProtKB=W5MND0 W5MND0 PTHR43066:SF16 RHOMBOID-RELATED PROTEIN RHOMBOID DOMAIN-CONTAINING PROTEIN 3 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011724.1|UniProtKB=W5N1A2 W5N1A2 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule localization#GO:0033036;lipid transport#GO:0006869;transport#GO:0006810;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;establishment of localization#GO:0051234;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid localization#GO:0010876;localization#GO:0051179;ceramide metabolic process#GO:0006672 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000007962.1|UniProtKB=W5MMQ8 W5MMQ8 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005896.1|UniProtKB=W5MFG5 W5MFG5 PTHR23267:SF189 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR DELTA VARIABLE 3 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014648.1|UniProtKB=W5NBL7 W5NBL7 PTHR23426:SF73 FERREDOXIN/ADRENODOXIN FERREDOXIN 1B cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011626.1|UniProtKB=W5N0Y0 W5N0Y0 PTHR14003:SF37 TRANSCRIPTIONAL REPRESSOR PROTEIN YY YY2 TRANSCRIPTION FACTOR double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;PcG protein complex#GO:0031519;chromosome#GO:0005694;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000006717.1|UniProtKB=W5MIA5 W5MIA5 PTHR11022:SF66 PEPTIDOGLYCAN RECOGNITION PROTEIN N-ACETYLMURAMOYL-L-ALANINE AMIDASE signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783 defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010950.1|UniProtKB=W5MYH2 W5MYH2 PTHR40472:SF6 RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN GLIA MATURATION FACTOR LEPOC|Ensembl=ENSLOCG00000001383.1|UniProtKB=W5LZL6 W5LZL6 PTHR45976:SF4 ARMADILLO SEGMENT POLARITY PROTEIN CATENIN BETA-1 transcription coactivator activity#GO:0003713;protein phosphatase binding#GO:0019903;transcription coregulator activity#GO:0003712;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297;binding#GO:0005488;phosphatase binding#GO:0019902;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;Wnt signaling pathway#GO:0016055;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;cell adhesion#GO:0007155;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell-cell junction#GO:0005911;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944 p53 pathway feedback loops 2#P04398>beta-catenin#P04670;CCKR signaling map#P06959>beta-catenin#P07150;Gonadotropin-releasing hormone receptor pathway#P06664>CTNNB1#P06838;Cadherin signaling pathway#P00012>betacatenin#P00463;Wnt signaling pathway#P00057>Beta-Catenin#P01432;Angiogenesis#P00005>beta catenin#P00187;Alzheimer disease-presenilin pathway#P00004>beta-catenin#P00156 LEPOC|Ensembl=ENSLOCG00000010682.1|UniProtKB=W5MXH6 W5MXH6 PTHR20988:SF2 TRANSMEMBRANE PROTEIN 183A-RELATED TRANSMEMBRANE PROTEIN 183A-RELATED intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000000204.1|UniProtKB=W5LVS0 W5LVS0 PTHR23411:SF41 TAPASIN IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009103.1|UniProtKB=W5MRZ0 W5MRZ0 PTHR10063:SF3 TUBERIN RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-1 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000014036.1|UniProtKB=W5N9J2 W5N9J2 PTHR10985:SF130 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY-RELATED 8A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000017047.1|UniProtKB=W5NKA7 W5NKA7 PTHR46306:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 9 BTB_POZ DOMAIN-CONTAINING PROTEIN 9 circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of signaling#GO:0023051;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014422.1|UniProtKB=W5NAU7 W5NAU7 PTHR14485:SF3 TETRATRICOPEPTIDE REPEAT PROTEIN 23 TETRATRICOPEPTIDE REPEAT PROTEIN 23 LEPOC|Ensembl=ENSLOCG00000011707.1|UniProtKB=W5N180 W5N180 PTHR14972:SF7 AGAP011572-PA PROTEIN FAM117A LEPOC|Ensembl=ENSLOCG00000009467.1|UniProtKB=W5MT49 W5MT49 PTHR24248:SF17 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1B ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;regulation of biological quality#GO:0065008;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signal transduction#GO:0007165;cellular process#GO:0009987;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000017411.1|UniProtKB=W5NLK7 W5NLK7 PTHR23137:SF36 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2C LEPOC|Ensembl=ENSLOCG00000009214.1|UniProtKB=W5MS83 W5MS83 PTHR14382:SF1 MDM2-BINDING PROTEIN MDM2-BINDING PROTEIN positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of mitotic cell cycle#GO:0007346;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;protein localization to kinetochore#GO:0034501;macromolecule localization#GO:0033036;positive regulation of mitotic cell cycle#GO:0045931;intracellular protein localization#GO:0008104;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;localization#GO:0051179;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045 condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000015367.1|UniProtKB=W5NE53 W5NE53 PTHR46925:SF4 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED SUBSTANCE-P RECEPTOR neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of reproductive process#GO:2000241;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;regulation of microtubule-based process#GO:0032886;positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145 membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;organelle#GO:0043226;motile cilium#GO:0031514;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 CCKR signaling map#P06959>TACR1#G07279;CCKR signaling map#P06959>TACR1#G06985 LEPOC|Ensembl=ENSLOCG00000013828.1|UniProtKB=W5N8U0 W5N8U0 PTHR24056:SF164 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 6 ISOFORM X1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016009.1|UniProtKB=W5NGG0 W5NGG0 PTHR12874:SF9 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 48 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005 LEPOC|Ensembl=ENSLOCG00000002355.1|UniProtKB=W5M325 W5M325 PTHR46708:SF13 TENASCIN TENASCIN-R extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000013941.1|UniProtKB=W5N984 W5N984 PTHR10841:SF20 SYNAPSIN SYNAPSIN-2 cytoskeletal adaptor activity#GO:0008093;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization#GO:0016043;cell junction organization#GO:0034330;synapse organization#GO:0050808;organelle localization#GO:0051640;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synapsin#P05775 LEPOC|Ensembl=ENSLOCG00000015661.1|UniProtKB=W5NF88 W5NF88 PTHR10183:SF268 CALPAIN CALPAIN-2 CATALYTIC SUBUNIT catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 LEPOC|Ensembl=ENSLOCG00000006094.1|UniProtKB=W5MG58 W5MG58 PTHR22538:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 74 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 74 LEPOC|Ensembl=ENSLOCG00000003165.1|UniProtKB=W5M5T1 W5M5T1 PTHR46685:SF1 28S RIBOSOMAL PROTEIN S15, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US15M membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014119.1|UniProtKB=W5N9T5 W5N9T5 PTHR45704:SF6 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE PROTEIN FAMILY MEMBER 11B LEPOC|Ensembl=ENSLOCG00000003727.1|UniProtKB=W5M7W7 W5M7W7 PTHR48249:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007 intracellular organelle#GO:0043229;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000010337.1|UniProtKB=W5MWA6 W5MWA6 PTHR12027:SF93 WNT RELATED PROTEIN WNT-2B molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125 Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;system development#GO:0048731;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 LEPOC|Ensembl=ENSLOCG00000012103.1|UniProtKB=W5N2N5 W5N2N5 PTHR43655:SF9 ATP-DEPENDENT PROTEASE MITOCHONDRIAL INNER MEMBRANE M-AAA PROTEASE COMPONENT AFG3L2 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;peptidase complex#GO:1905368;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000003566.1|UniProtKB=W5M767 W5M767 PTHR21258:SF43 DOCKING PROTEIN RELATED DOCKING PROTEIN 6 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001886.1|UniProtKB=W5M1C7 W5M1C7 PTHR24070:SF268 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN M-RAS pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 Ras protein signal transduction#GO:0007265;establishment or maintenance of cell polarity#GO:0007163;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Ras#P00552 LEPOC|Ensembl=ENSLOCG00000011290.1|UniProtKB=W5MZR9 W5MZR9 PTHR45941:SF1 ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2-LIKE-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373 multicellular organismal-level homeostasis#GO:0048871;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;oligosaccharide biosynthetic process#GO:0009312;protein metabolic process#GO:0019538;homeostasis of number of cells#GO:0048872;biological process involved in interspecies interaction between organisms#GO:0044419;carbohydrate metabolic process#GO:0005975;homeostatic process#GO:0042592;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000007922.1|UniProtKB=W5MML3 W5MML3 PTHR16222:SF43 ADP-RIBOSYLGLYCOHYDROLASE SELENOPROTEIN J catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007760.1|UniProtKB=W5MM19 W5MM19 PTHR45655:SF10 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;lyase activity#GO:0016829 response to abiotic stimulus#GO:0009628;response to oxygen levels#GO:0070482;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cytosol#GO:0005829 guanylate cyclase#PC00114;cyclase#PC00079 LEPOC|Ensembl=ENSLOCG00000001790.1|UniProtKB=W5M119 W5M119 PTHR11348:SF22 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 5 carbohydrate derivative binding#GO:0097367;cell adhesion molecule binding#GO:0050839;heparin binding#GO:0008201;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102;glycosaminoglycan binding#GO:0005539;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cell adhesion#GO:0007155;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of developmental process#GO:0050793;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001103.1|UniProtKB=W5LYP2 W5LYP2 PTHR13723:SF26 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 10 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000008653.1|UniProtKB=W5MQ65 W5MQ65 PTHR46916:SF1 TRANSMEMBRANE PROTEIN 205 SI:CH211-121A2.4 LEPOC|Ensembl=ENSLOCG00000017210.1|UniProtKB=W5NKW9 W5NKW9 PTHR24024:SF14 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A COLLECTIN-11 molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of immune system process#GO:0002682;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;immune system process#GO:0002376;regulation of immune response#GO:0050776;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;immune response#GO:0006955;complement activation#GO:0006956;activation of immune response#GO:0002253;positive regulation of response to stimulus#GO:0048584;defense response to other organism#GO:0098542;biological regulation#GO:0065007;response to other organism#GO:0051707;humoral immune response#GO:0006959;positive regulation of immune response#GO:0050778;immune effector process#GO:0002252;regulation of response to stimulus#GO:0048583;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211;surfactant#PC00212 LEPOC|Ensembl=ENSLOCG00000008140.1|UniProtKB=W5MNC2 W5MNC2 PTHR22611:SF1 PROTEIN NAKED CUTICLE PROTEIN NAKED CUTICLE HOMOLOG 2 negative regulation of cell communication#GO:0010648;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of Wnt signaling pathway#GO:0030178;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Wnt signaling pathway#P00057>Naked#P01427 LEPOC|Ensembl=ENSLOCG00000015431.1|UniProtKB=W5NED2 W5NED2 PTHR23257:SF750 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 21 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000006256.1|UniProtKB=W5MGP5 W5MGP5 EBI3 PTHR48483:SF3 INTERLEUKIN-27 SUBUNIT BETA INTERLEUKIN 27 RECEPTOR BETA cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 T cell activation#GO:0042110;leukocyte activation#GO:0045321;cellular process#GO:0009987;multicellular organismal process#GO:0032501;lymphocyte proliferation#GO:0046651;lymphocyte activation#GO:0046649;mononuclear cell proliferation#GO:0032943;T cell proliferation#GO:0042098;immune system process#GO:0002376;cell activation#GO:0001775;cell population proliferation#GO:0008283;leukocyte proliferation#GO:0070661 LEPOC|Ensembl=ENSLOCG00000006419.1|UniProtKB=W5MH97 W5MH97 PTHR11256:SF48 BCL-2 RELATED BCL-2-RELATED OVARIAN KILLER PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;signaling#GO:0023052;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554 membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Apoptosis signaling pathway#P00006>Bok#P00261 LEPOC|Ensembl=ENSLOCG00000009835.1|UniProtKB=W5MUH2 W5MUH2 PTHR13817:SF84 TITIN CONTACTIN-3 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009017.1|UniProtKB=W5MRJ1 W5MRJ1 PTHR24103:SF611 E3 UBIQUITIN-PROTEIN LIGASE TRIM BBOX AND DUF4200 DOMAIN-CONTAINING PROTEIN-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010002.1|UniProtKB=W5MV24 W5MV24 PTHR11692:SF0 BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleoside phosphate biosynthetic process#GO:1901293;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;IMP metabolic process#GO:0046040;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 De novo purine biosynthesis#P02738>AICAR transformylase#P02900;De novo purine biosynthesis#P02738>IMP cyclohydrolase#P02894 LEPOC|Ensembl=ENSLOCG00000010258.1|UniProtKB=W5MVZ7 W5MVZ7 PTHR12128:SF21 DIHYDRODIPICOLINATE SYNTHASE N-ACETYLNEURAMINATE LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 lyase#PC00144 N-acetylglucosamine metabolism#P02756>N-acetylneuraminate lyase#P03040 LEPOC|Ensembl=ENSLOCG00000012670.1|UniProtKB=W5N4N4 W5N4N4 PTHR10838:SF19 SYNAPTOGYRIN SYNAPTOGYRIN-2 LIKE PROTEIN-RELATED cellular component organization#GO:0016043;synaptic vesicle membrane organization#GO:0048499;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;export from cell#GO:0140352;membrane organization#GO:0061024;regulated exocytosis#GO:0045055;transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;secretion#GO:0046903;establishment of localization#GO:0051234;secretion by cell#GO:0032940;exocytosis#GO:0006887 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cell junction#GO:0030054;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006461.1|UniProtKB=W5MHE6 W5MHE6 PTHR31139:SF5 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG PROTEIN LIMB EXPRESSION 1 HOMOLOG organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000010797.1|UniProtKB=W5MXZ0 W5MXZ0 PTHR11647:SF57 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 3 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;dihydropyrimidinase activity#GO:0004157;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleobase catabolic process#GO:0046113;actin cytoskeleton organization#GO:0030036;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;cytoskeleton organization#GO:0007010;metabolic process#GO:0008152;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;actin filament organization#GO:0007015;pyrimidine nucleobase metabolic process#GO:0006206;cellular component organization or biogenesis#GO:0071840 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 LEPOC|Ensembl=ENSLOCG00000017052.1|UniProtKB=W5NKB5 W5NKB5 PTHR16121:SF0 CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009947.1|UniProtKB=W5MUV6 W5MUV6 PTHR12623:SF9 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 Gonadotropin-releasing hormone receptor pathway#P06664>NAB#P06801 LEPOC|Ensembl=ENSLOCG00000016753.1|UniProtKB=W5NJ96 W5NJ96 PTHR21028:SF2 SI:CH211-156B7.4 CYTH DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005404.1|UniProtKB=W5MDQ8 W5MDQ8 PTHR12737:SF17 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE N(G),N(G)-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;regulation of cellular process#GO:0050794;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;biological regulation#GO:0065007 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009658.1|UniProtKB=W5MTU4 W5MTU4 PTHR46134:SF7 DRONGO, ISOFORM F ARF-GAP DOMAIN AND FG REPEAT-CONTAINING PROTEIN 1 reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;spermatid development#GO:0007286;sexual reproduction#GO:0019953;male gamete generation#GO:0048232;nucleus organization#GO:0006997;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;gamete generation#GO:0007276;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;spermatid differentiation#GO:0048515;intermediate filament-based process#GO:0045103;acrosome assembly#GO:0001675;intermediate filament organization#GO:0045109;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;vesicle organization#GO:0016050;cellular anatomical entity morphogenesis#GO:0032989 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000005379.1|UniProtKB=W5MDM3 W5MDM3 PTHR42799:SF2 MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000369.1|UniProtKB=W5LW94 W5LW94 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015530.1|UniProtKB=W5NER0 W5NER0 PTHR24261:SF8 PLASMINOGEN-RELATED HEPATOCYTE GROWTH FACTOR signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007728.1|UniProtKB=W5MLX3 W5MLX3 PTHR24329:SF303 HOMEOBOX PROTEIN ARISTALESS PAIRED MESODERM HOMEOBOX PROTEIN 2A RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;developmental process#GO:0032502;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000008894.1|UniProtKB=W5MR35 W5MR35 PTHR11533:SF31 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE Q metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;peptide catabolic process#GO:0043171;primary metabolic process#GO:0044238;catabolic process#GO:0009056;proteolysis#GO:0006508;metabolic process#GO:0008152;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014071.1|UniProtKB=W5N9N4 W5N9N4 PTHR12378:SF41 DESUMOYLATING ISOPEPTIDASE PALMITOYL-PROTEIN HYDROLASE catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000003303.1|UniProtKB=W5M698 W5M698 EIF3H PTHR10410:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT H peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;translation initiation factor activity#GO:0003743;catalytic activity, acting on a protein#GO:0140096;translation factor activity#GO:0180051;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005 metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852;ribonucleoprotein complex#GO:1990904 translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000010005.1|UniProtKB=W5MV32 W5MV32 PTHR22774:SF15 CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 3A lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 lipid localization#GO:0010876;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000010180.1|UniProtKB=W5MVQ5 W5MVQ5 PTHR21237:SF25 GRPE PROTEIN GRPE PROTEIN HOMOLOG 1, MITOCHONDRIAL nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008069.1|UniProtKB=W5MN45 W5MN45 PTHR12496:SF2 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25B RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000000283.1|UniProtKB=W5LW02 W5LW02 PTHR48071:SF41 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014456.1|UniProtKB=W5NAY1 W5NAY1 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;enzyme binding#GO:0019899;extracellular matrix structural constituent#GO:0005201 reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;fertilization#GO:0009566;cell differentiation#GO:0030154;gamete generation#GO:0007276;regulation of biological process#GO:0050789;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;binding of sperm to zona pellucida#GO:0007339;sexual reproduction#GO:0019953;cell recognition#GO:0008037;biological regulation#GO:0065007;oogenesis#GO:0048477;regulation of reproductive process#GO:2000241;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;single fertilization#GO:0007338;cell-cell recognition#GO:0009988;cellular developmental process#GO:0048869;developmental process#GO:0032502;sperm-egg recognition#GO:0035036 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003434.1|UniProtKB=W5M6Q9 W5M6Q9 PTHR23192:SF31 OLFACTOMEDIN-RELATED OLFACTOMEDIN-RELATED cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014367.1|UniProtKB=W5NAN2 W5NAN2 PTHR12652:SF22 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11A cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;organelle organization#GO:0006996;cellular component organization#GO:0016043;peroxisome organization#GO:0007031;cellular process#GO:0009987 membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012212.1|UniProtKB=W5N331 W5N331 PTHR43462:SF1 ALANYL-TRNA EDITING PROTEIN ALANYL-TRNA EDITING PROTEIN AARSD1 deacylase activity#GO:0160215;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101 biological regulation#GO:0065007;regulation of biological quality#GO:0065008 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017215.1|UniProtKB=W5NKX5 W5NKX5 PTHR14205:SF15 WD-REPEAT PROTEIN EARP AND GARP COMPLEX-INTERACTING PROTEIN 1 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 LEPOC|Ensembl=ENSLOCG00000012945.1|UniProtKB=W5N5P7 W5N5P7 PTHR21497:SF27 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011427.1|UniProtKB=W5N088 W5N088 PTHR15692:SF19 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 1 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;Notch signaling pathway#GO:0007219;regulation of biosynthetic process#GO:0009889 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 Notch signaling pathway#P00045>Mastermind#P01106 LEPOC|Ensembl=ENSLOCG00000012473.1|UniProtKB=W5N408 W5N408 PTHR31658:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010751.1|UniProtKB=W5MXR1 W5MXR1 PTHR16134:SF2 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 21-RELATED ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;photoperiodism#GO:0009648;macromolecule metabolic process#GO:0043170;response to external stimulus#GO:0009605;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of circadian rhythm#GO:0042752;cellular process#GO:0009987;response to radiation#GO:0009314;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007268.1|UniProtKB=W5MK96 W5MK96 PTHR16088:SF3 YY1 ASSOCIATED PROTEIN-RELATED GON-4-LIKE PROTEIN transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000018064.1|UniProtKB=W5NNF6 W5NNF6 PTHR47510:SF11 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011293.1|UniProtKB=W5MZS0 W5MZS0 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR-RELATED binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012117.1|UniProtKB=W5N2Q0 W5N2Q0 PTHR16509:SF1 FAMILY NOT NAMED MANGANESE-DEPENDENT ADP-RIBOSE_CDP-ALCOHOL DIPHOSPHATASE cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;transition metal ion binding#GO:0046914;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 LEPOC|Ensembl=ENSLOCG00000002678.1|UniProtKB=W5M438 W5M438 PTHR42757:SF22 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED LIMBIC SYSTEM-ASSOCIATED MEMBRANE PROTEIN regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;regulation of biological process#GO:0050789;cell-cell adhesion#GO:0098609;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000012752.1|UniProtKB=W5N4Y1 W5N4Y1 PTHR15417:SF2 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1B protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;cellular response to nitrogen compound#GO:1901699;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell body#GO:0044297;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025 phosphatase inhibitor#PC00183;protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 Nicotine pharmacodynamics pathway#P06587>PPP1R1B#P06589;Dopamine receptor mediated signaling pathway#P05912>DARPP-32#P05950 LEPOC|Ensembl=ENSLOCG00000015472.1|UniProtKB=W5NEI4 W5NEI4 PTHR31022:SF7 CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN-LIKE microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of organelle assembly#GO:1902115;regulation of mitotic spindle assembly#GO:1901673;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of spindle organization#GO:0090224;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of spindle assembly#GO:0090169;regulation of mitotic spindle organization#GO:0060236;regulation of microtubule-based process#GO:0032886 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;spindle#GO:0005819;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000002336.1|UniProtKB=W5M2X4 W5M2X4 PTHR31004:SF3 TRANSMEMBRANE PROTEIN 79 TRANSMEMBRANE PROTEIN 79A localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;secretion by cell#GO:0032940;exocytosis#GO:0006887;regulated exocytosis#GO:0045055;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 vacuole#GO:0005773;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;lysosomal membrane#GO:0005765;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001185.1|UniProtKB=W5LYX8 W5LYX8 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003947.1|UniProtKB=W5M8L6 W5M8L6 PTHR14191:SF20 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515 protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;cellular process#GO:0009987;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000153.1|UniProtKB=W5LVL4 W5LVL4 PTHR46333:SF4 CYTOKINESIS PROTEIN 3 TRANSGLUTAMINASE-LIKE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011128.1|UniProtKB=W5MZ76 W5MZ76 PTHR45626:SF50 TRANSCRIPTION TERMINATION FACTOR 2-RELATED TRANSCRIPTION TERMINATION FACTOR 2 catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 LEPOC|Ensembl=ENSLOCG00000001429.1|UniProtKB=W5LZS1 W5LZS1 PTHR22776:SF25 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 6 response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;immune system process#GO:0002376;immune response#GO:0006955;regulation of biological process#GO:0050789 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;recycling endosome#GO:0055037;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006638.1|UniProtKB=W5MI10 W5MI10 PTHR10201:SF20 MATRIX METALLOPROTEINASE STROMELYSIN-3 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000002526.1|UniProtKB=W5M3N4 W5M3N4 PTHR11849:SF319 ETS PROTEIN C-ETS-1 ISOFORM X1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 VEGF signaling pathway#P00056>Ets#P01419;PDGF signaling pathway#P00047>Ets#P01167;Angiogenesis#P00005>Ets#P00188;Ras Pathway#P04393>Ets#P04563 LEPOC|Ensembl=ENSLOCG00000015531.1|UniProtKB=W5NEQ5 W5NEQ5 PTHR15205:SF2 DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;apoptotic signaling pathway#GO:0097190;cell surface receptor signaling pathway#GO:0007166;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;cell death#GO:0008219;cell communication#GO:0007154 cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001951.1|UniProtKB=W5M1J7 W5M1J7 PTHR12935:SF14 GAMMA-GLUTAMYLCYCLOTRANSFERASE GAMMA-GLUTAMYL CYCLOTRANSFERASE lyase activity#GO:0016829;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000015526.1|UniProtKB=W5NEP8 W5NEP8 PTHR48071:SF28 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008423.1|UniProtKB=W5MPD6 W5MPD6 PTHR42707:SF2 ACYL-COA DEHYDROGENASE ACD11 DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004483.1|UniProtKB=W5MAE8 W5MAE8 PTHR21472:SF28 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000006610.1|UniProtKB=W5MHX9 W5MHX9 PTHR19143:SF222 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 3 enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;homeostatic process#GO:0042592;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;organophosphate catabolic process#GO:0046434;triglyceride homeostasis#GO:0070328;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;cholesterol homeostasis#GO:0042632;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000008481.1|UniProtKB=W5MPL8 W5MPL8 PTHR43238:SF1 GDP-L-FUCOSE SYNTHASE GDP-L-FUCOSE SYNTHASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007209.1|UniProtKB=W5MK19 W5MK19 PTHR11972:SF206 NADPH OXIDASE NADPH OXIDASE 4 oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;catalytic activity#GO:0003824 defense response#GO:0006952;superoxide metabolic process#GO:0006801;response to stimulus#GO:0050896;cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;response to stress#GO:0006950;metabolic process#GO:0008152 catalytic complex#GO:1902494;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 oxidase#PC00175;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011960.1|UniProtKB=W5N247 W5N247 PTHR23320:SF157 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED SI:CH1073-291C23.2 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004007.1|UniProtKB=W5M8S7 W5M8S7 PTHR12232:SF3 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 3 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000006240.1|UniProtKB=W5MGN0 W5MGN0 PTHR24085:SF7 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR GAMMA RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor binding#GO:0140297;nuclear receptor binding#GO:0016922;sequence-specific DNA binding#GO:0043565 response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to hormone#GO:0009725;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;response to peptide hormone#GO:0043434;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006304.1|UniProtKB=W5MGV3 W5MGV3 PTHR46440:SF2 HOMEOBOX PROTEIN HOX-D12-RELATED HOMEOBOX PROTEIN HOX-C12 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000005028.1|UniProtKB=W5MCE7 W5MCE7 PTHR11347:SF194 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1B phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cell body#GO:0044297;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010684.1|UniProtKB=W5MXI4 W5MXI4 PTHR22792:SF50 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 1B binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010569.1|UniProtKB=W5MX46 W5MX46 PTHR45652:SF5 GLIAL FIBRILLARY ACIDIC PROTEIN VIMENTIN structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;axon#GO:0030424;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000004370.1|UniProtKB=W5MA12 W5MA12 PTHR44665:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 14 DNAJ HOMOLOG SUBFAMILY C MEMBER 14 G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000010184.1|UniProtKB=W5MVQ8 W5MVQ8 PTHR47888:SF1 UPF0730 PROTEIN ENCODED BY LINC00643-RELATED SERTA DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000000424.1|UniProtKB=W5LWF5 W5LWF5 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014147.1|UniProtKB=W5N9W9 W5N9W9 PTHR45913:SF21 EPM2A-INTERACTING PROTEIN 1 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2-LIKE LEPOC|Ensembl=ENSLOCG00000011342.1|UniProtKB=W5MZY3 W5MZY3 PTHR14218:SF41 PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2 TRIPEPTIDYL-PEPTIDASE 1 catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;developmental process#GO:0032502;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;central nervous system development#GO:0007417;primary metabolic process#GO:0044238;system development#GO:0048731;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;protein catabolic process#GO:0030163;protein catabolic process in the vacuole#GO:0007039;proteolysis#GO:0006508;animal gross anatomical part developmental process#GO:0160108 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000012261.1|UniProtKB=W5N386 W5N386 PTHR19855:SF12 WD40 REPEAT PROTEIN 12, 37 WD REPEAT-CONTAINING PROTEIN 37 LEPOC|Ensembl=ENSLOCG00000010322.1|UniProtKB=W5MW97 W5MW97 PTHR12745:SF11 SUPPRESSION OF TUMORIGENICITY 7 SUPPRESSOR OF TUMORIGENICITY 7 PROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000014891.1|UniProtKB=W5NCH8 W5NCH8 PTHR24409:SF315 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 711 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000004302.1|UniProtKB=W5M9T3 W5M9T3 PTHR13130:SF4 34 KDA TRANSCRIPTIONAL CO-ACTIVATOR-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 27 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000006820.1|UniProtKB=W5MIQ3 W5MIQ3 PTHR11537:SF184 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL KCNC3 transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 action potential#GO:0001508;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transport#GO:0006813;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234 cell leading edge#GO:0031252;presynapse#GO:0098793;neuron projection#GO:0043005;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351;postsynapse#GO:0098794;cell body#GO:0044297;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;presynaptic membrane#GO:0042734;neuron projection membrane#GO:0032589;voltage-gated potassium channel complex#GO:0008076;axon terminus#GO:0043679;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;neuron projection terminus#GO:0044306;neuronal cell body#GO:0043025;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;transmembrane transporter complex#GO:1902495 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016072.1|UniProtKB=W5NGP6 W5NGP6 PTHR12669:SF14 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1 binding#GO:0005488;translation regulator activity#GO:0045182;protein binding#GO:0005515;translation initiation factor binding#GO:0031369 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224;translation factor#PC00223 p53 pathway by glucose deprivation#P04397>4E-BP1#P04637;p38 MAPK pathway#P05918>4E-BP1#P06042;CCKR signaling map#P06959>4E-BP1#P07230 LEPOC|Ensembl=ENSLOCG00000014092.1|UniProtKB=W5N9Q2 W5N9Q2 PTHR12650:SF15 40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI RIBOSOMAL PROTEIN S30, ISOFORM A membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000006569.1|UniProtKB=W5MHS4 W5MHS4 PTHR46756:SF31 TRANSGELIN GROWTH ARREST-SPECIFIC PROTEIN 2 ISOFORM X1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000008133.1|UniProtKB=W5MNB7 W5MNB7 PTHR24372:SF72 GLYCOPROTEIN HORMONE RECEPTOR RELAXIN RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003125.1|UniProtKB=W5M5M5 W5M5M5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013072.1|UniProtKB=W5N641 W5N641 PTHR18945:SF912 NEUROTRANSMITTER GATED ION CHANNEL LIGAND-GATED CATION CHANNEL ZACN monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276 transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;trans-synaptic signaling#GO:0099537;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;metal ion transport#GO:0030001 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000002958.1|UniProtKB=W5M565 W5M565 PTHR15208:SF2 RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS CANCER ASSOCIATED SURFACE ANTIGEN RCAS1 ESTROGEN RECEPTOR-BINDING FRAGMENT- ASSOCIATED GENE 9 PROTEIN RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000017621.1|UniProtKB=W5NM67 W5NM67 PTHR18884:SF128 SEPTIN SI:CH211-282J17.13-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 intracellular protein localization#GO:0008104;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301;macromolecule localization#GO:0033036;cell cycle#GO:0007049 cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000011779.1|UniProtKB=W5N1I1 W5N1I1 PTHR44653:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000014454.1|UniProtKB=W5NAY3 W5NAY3 PTHR24349:SF64 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 3 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein serine/threonine kinase activity#GO:0004674;kinase binding#GO:0019900;binding#GO:0005488;mitogen-activated protein kinase binding#GO:0051019;kinase activity#GO:0016301;calmodulin binding#GO:0005516;transferase activity#GO:0016740 regulation of response to external stimulus#GO:0032101;response to cytokine#GO:0034097;response to chemical#GO:0042221;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;response to stimulus#GO:0050896;signaling#GO:0023052;toll-like receptor signaling pathway#GO:0002224;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to peptide#GO:1901652;immune system process#GO:0002376;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;regulation of innate immune response#GO:0045088;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Angiogenesis#P00005>MAPKAPK2/3#P00244;p38 MAPK pathway#P05918>MAPKAP-K3#P05919;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415;Ras Pathway#P04393>MAPKAP#P04564 LEPOC|Ensembl=ENSLOCG00000002805.1|UniProtKB=W5M4L0 W5M4L0 PTHR10896:SF19 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000004914.1|UniProtKB=W5MC58 W5MC58 PTHR14222:SF1 CONDENSIN CONDENSIN-2 COMPLEX SUBUNIT D3 binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;nuclear division#GO:0000280;sexual reproduction#GO:0019953 chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;condensin complex#GO:0000796;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000013800.1|UniProtKB=W5N8Q6 W5N8Q6 PTHR31144:SF1 UPF0602 PROTEIN C4ORF47 CILIA-AND FLAGELLA-ASSOCIATED PROTEIN 96 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813 LEPOC|Ensembl=ENSLOCG00000007046.1|UniProtKB=W5MJH1 W5MJH1 PTHR31817:SF3 FAMILY NOT NAMED TYROSINE CARBOXYPEPTIDASE MATCAP2-RELATED LEPOC|Ensembl=ENSLOCG00000015569.1|UniProtKB=W5NEW0 W5NEW0 PTHR11547:SF52 ARGININE OR CREATINE KINASE CREATINE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular process#GO:0009987;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 amino acid kinase#PC00045;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011557.1|UniProtKB=W5N0P3 W5N0P3 PTHR11660:SF50 SOLUTE CARRIER FAMILY 40 MEMBER FERROPORTIN ISOFORM X1 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009320.1|UniProtKB=W5MSL4 W5MSL4 PTHR15721:SF2 KIAA0586 PROTEIN PROTEIN TALPID3 cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000013906.1|UniProtKB=W5N935 W5N935 PTHR48614:SF3 AT03386P MAPK-REGULATED COREPRESSOR-INTERACTING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000012635.1|UniProtKB=W5N4J5 W5N4J5 PTHR34260:SF1 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 cellular component assembly#GO:0022607;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000006987.1|UniProtKB=W5MJA9 W5MJA9 PTHR14222:SF2 CONDENSIN CONDENSIN COMPLEX SUBUNIT 1 histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;sister chromatid segregation#GO:0000819;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;nuclear division#GO:0000280;sexual reproduction#GO:0019953;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059 chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;condensin complex#GO:0000796;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006406.1|UniProtKB=W5MH75 W5MH75 PTHR10570:SF8 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular developmental process#GO:0048869;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lymphocyte activation#GO:0046649;biological regulation#GO:0065007;T cell differentiation#GO:0030217;hemopoiesis#GO:0030097;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;cell communication#GO:0007154;immune system process#GO:0002376;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;mononuclear cell differentiation#GO:1903131;regulation of biological process#GO:0050789 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;side of membrane#GO:0098552 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD3 gamma#P01317 LEPOC|Ensembl=ENSLOCG00000012234.1|UniProtKB=W5N338 W5N338 PTHR11873:SF1 RETINOL-BINDING PROTEIN 4 PURPURIN transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000011094.1|UniProtKB=W5MZ24 W5MZ24 PTHR11937:SF14 ACTIN ACTIN-RELATED PROTEIN 10 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cellular localization#GO:0051641;localization#GO:0051179;retrograde axonal transport#GO:0008090;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;axonal transport#GO:0098930;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;mitochondrion localization#GO:0051646;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088 actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039 LEPOC|Ensembl=ENSLOCG00000008966.1|UniProtKB=W5MRD1 W5MRD1 PTHR10799:SF997 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5 catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;positive regulation of transcription by RNA polymerase II#GO:0045944;heterochromatin organization#GO:0070828;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000010831.1|UniProtKB=W5MY22 W5MY22 PTHR11388:SF87 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2B1 active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 basal part of cell#GO:0045178;apical plasma membrane#GO:0016324;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical part of cell#GO:0045177 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002827.1|UniProtKB=W5M4M3 W5M4M3 PTHR10153:SF38 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 1 ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515;transporter activity#GO:0005215;calmodulin binding#GO:0005516;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 cellular process#GO:0009987;potassium ion transport#GO:0006813;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000013957.1|UniProtKB=W5N9A0 W5N9A0 PTHR12547:SF177 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36 molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011333.1|UniProtKB=W5MZX7 W5MZX7 PTHR15337:SF1 ANTERIOR GRADIENT PROTEIN-RELATED ANTERIOR GRADIENT PROTEIN 2 HOMOLOG inflammatory response#GO:0006954;response to stress#GO:0006950;defense response#GO:0006952;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000001172.1|UniProtKB=W5LYX6 W5LYX6 PTHR24349:SF254 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-INTERACTING SERINE_THREONINE-PROTEIN KINASE 2 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Interleukin signaling pathway#P00036>MNK1/2#P00972;PDGF signaling pathway#P00047>MNK1/2#P01149;p38 MAPK pathway#P05918>MNK2#P06017;Oxidative stress response#P00046>MNK1/2#P01137 LEPOC|Ensembl=ENSLOCG00000017733.1|UniProtKB=W5NMH8 W5NMH8 PTHR21255:SF55 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 4 protein binding#GO:0005515;binding#GO:0005488 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000007109.1|UniProtKB=W5MJQ6 W5MJQ6 PTHR23503:SF136 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 import across plasma membrane#GO:0098739;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carbohydrate transport#GO:0008643;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000007601.1|UniProtKB=W5MLG8 W5MLG8 PTHR10408:SF7 STEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 acyltransferase#PC00042;transferase#PC00220 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 LEPOC|Ensembl=ENSLOCG00000006261.1|UniProtKB=W5MGQ6 W5MGQ6 PTHR16399:SF32 GASDERMIN PEJVAKIN transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014588.1|UniProtKB=W5NBE4 W5NBE4 PTHR24366:SF166 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 3 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000015898.1|UniProtKB=W5NG17 W5NG17 PTHR12001:SF44 GERANYLGERANYL PYROPHOSPHATE SYNTHASE GERANYLGERANYL PYROPHOSPHATE SYNTHASE prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238;isoprenoid metabolic process#GO:0006720;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 LEPOC|Ensembl=ENSLOCG00000004436.1|UniProtKB=W5MA93 W5MA93 PTHR22443:SF14 NON-SPECIFIC LETHAL 1, ISOFORM M KAT8 REGULATORY NSL COMPLEX SUBUNIT 1 protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545 LEPOC|Ensembl=ENSLOCG00000006901.1|UniProtKB=W5MIY6 W5MIY6 PTHR12015:SF108 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 20 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 LEPOC|Ensembl=ENSLOCG00000018317.1|UniProtKB=W5NP59 W5NP59 PTHR12611:SF2 PUR-TRANSCRIPTIONAL ACTIVATOR TRANSCRIPTIONAL ACTIVATOR PROTEIN PUR-ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000017546.1|UniProtKB=W5NLZ2 W5NLZ2 PTHR22750:SF24 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 3 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008362.1|UniProtKB=W5MP45 W5MP45 PTHR10996:SF257 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010296.1|UniProtKB=W5MW50 W5MW50 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002694.1|UniProtKB=W5M456 W5M456 PTHR32493:SF0 SUSHI DOMAIN-CONTAINING PROTEIN 5 SUSHI DOMAIN-CONTAINING PROTEIN 5 Notch signaling pathway#GO:0007219;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000007180.1|UniProtKB=W5MJY0 W5MJY0 PTHR46962:SF1 SERINE/THREONINE-PROTEIN KINASE KIST SERINE_THREONINE-PROTEIN KINASE KIST phosphotransferase activity, alcohol group as acceptor#GO:0016773;ribonucleoprotein complex binding#GO:0043021;protein kinase activity#GO:0004672;protein-containing complex binding#GO:0044877;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of gene expression#GO:0010628;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of translation#GO:0045727;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;positive regulation of protein metabolic process#GO:0051247;regulation of translational initiation#GO:0006446;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;neuron projection#GO:0043005;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;neuron projection cytoplasm#GO:0120111 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005663.1|UniProtKB=W5MEN5 W5MEN5 PTHR12934:SF15 50S RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000013299.1|UniProtKB=W5N6Y1 W5N6Y1 PTHR23192:SF85 OLFACTOMEDIN-RELATED GLIOMEDIN cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009469.1|UniProtKB=W5MT64 W5MT64 PTHR45850:SF9 SORTING NEXIN FAMILY MEMBER SORTING NEXIN transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000052.1|UniProtKB=W5LVA5 W5LVA5 PTHR24241:SF20 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V2 RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to hormone#GO:0009725;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;blood circulation#GO:0008015;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;system process#GO:0003008;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;circulatory system process#GO:0003013;cell communication#GO:0007154;regulation of biological quality#GO:0065008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005025.1|UniProtKB=W5MCF5 W5MCF5 PTHR22692:SF21 MYOSIN VII, XV MYOSIN XVA actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000012972.1|UniProtKB=W5N5R6 W5N5R6 PTHR45718:SF1 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLIS3 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012443.1|UniProtKB=W5N3V7 W5N3V7 PTHR46839:SF1 SUSHI DOMAIN-CONTAINING PROTEIN 6 SUSHI DOMAIN-CONTAINING 6 response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000009278.1|UniProtKB=W5MSF8 W5MSF8 PTHR15467:SF4 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000014295.1|UniProtKB=W5NAF5 W5NAF5 PTHR42776:SF1 SERINE PEPTIDASE S9 FAMILY MEMBER S9 FAMILY PEPTIDASE ISOFORM X1 serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014165.1|UniProtKB=W5N9Z1 W5N9Z1 PTHR10602:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 binding#GO:0005488;translation factor activity#GO:0180051;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;translation initiation factor activity#GO:0003743;ribosome binding#GO:0043022 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224;translation factor#PC00223 Apoptosis signaling pathway#P00006>ELF2alpha#P00307 LEPOC|Ensembl=ENSLOCG00000003672.1|UniProtKB=W5M7K3 W5M7K3 PTHR45982:SF12 REGULATOR OF CHROMOSOME CONDENSATION REGULATOR OF CHROMOSOME CONDENSATION GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of spindle organization#GO:0090224;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of spindle assembly#GO:0090169;regulation of mitotic spindle organization#GO:0060236;regulation of microtubule-based process#GO:0032886;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;regulation of organelle assembly#GO:1902115;regulation of mitotic spindle assembly#GO:1901673 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000000295.1|UniProtKB=W5LW55 W5LW55 PTHR46337:SF1 RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;mitochondrial ribosome assembly#GO:0061668;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;ribonucleoprotein complex biogenesis#GO:0022613;mitochondrion organization#GO:0007005;organelle fusion#GO:0048284;cellular component assembly#GO:0022607 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000013367.1|UniProtKB=W5N763 W5N763 PTHR20855:SF143 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR EPSILON signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017923.1|UniProtKB=W5NN17 W5NN17 PTHR11589:SF10 NERVE GROWTH FACTOR NGF -RELATED BETA-NERVE GROWTH FACTOR signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;neuron development#GO:0048666;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cellular response to endogenous stimulus#GO:0071495;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;response to endogenous stimulus#GO:0009719;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular response to nerve growth factor stimulus#GO:1990090;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;regulation of trans-synaptic signaling#GO:0099177;nervous system development#GO:0007399;negative regulation of neuron apoptotic process#GO:0043524;regulation of neuron apoptotic process#GO:0043523;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069 cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;presynapse#GO:0098793;secretory vesicle#GO:0099503;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;extracellular region#GO:0005576;exocytic vesicle#GO:0070382 growth factor#PC00112;neurotrophic factor#PC00163 LEPOC|Ensembl=ENSLOCG00000013797.1|UniProtKB=W5N8R0 W5N8R0 PTHR23271:SF1 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;binding#GO:0005488 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002243.1|UniProtKB=W5M2N6 W5M2N6 PTHR48027:SF23 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED DAZ-ASSOCIATED PROTEIN 1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;gamete generation#GO:0007276;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;sexual reproduction#GO:0019953;positive regulation of RNA metabolic process#GO:0051254;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;developmental process involved in reproduction#GO:0003006;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;spermatogenesis#GO:0007283;developmental process#GO:0032502;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;male gamete generation#GO:0048232;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007623.1|UniProtKB=W5MLI9 W5MLI9 PTHR13610:SF18 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN ATP SYNTHASE SUBUNIT C LYSINE N-METHYLTRANSFERASE ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007522.1|UniProtKB=W5ML85 W5ML85 PTHR24092:SF46 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE ID intramembrane lipid carrier activity#GO:0140303;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657 regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000009446.1|UniProtKB=W5MT24 W5MT24 PTHR17615:SF8 PROTEIN FAM189A ENDOSOMAL TRANSMEMBRANE EPSIN INTERACTOR 1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 transport#GO:0006810;cell surface receptor signaling pathway#GO:0007166;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;response to chemokine#GO:1990868;receptor internalization#GO:0031623;cellular process#GO:0009987;signal transduction#GO:0007165;vesicle-mediated transport#GO:0016192;response to cytokine#GO:0034097;response to chemical#GO:0042221;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cytokine-mediated signaling pathway#GO:0019221;localization#GO:0051179;chemokine-mediated signaling pathway#GO:0070098;cell communication#GO:0007154;response to peptide#GO:1901652;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to chemokine#GO:1990869;signaling#GO:0023052 intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;recycling endosome#GO:0055037;late endosome membrane#GO:0031902;early endosome membrane#GO:0031901;recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000016911.1|UniProtKB=W5NJV8 W5NJV8 PTHR24058:SF137 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001323.1|UniProtKB=W5LZE6 W5LZE6 PTHR15315:SF112 RING FINGER PROTEIN 41, 151 PDZ DOMAIN CONTAINING RING FINGER 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 LEPOC|Ensembl=ENSLOCG00000007735.1|UniProtKB=W5MLX9 W5MLX9 PTHR24404:SF28 ZINC FINGER PROTEIN ZINC FINGER PROTEIN EOS cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004060.1|UniProtKB=W5M8Z5 W5M8Z5 PTHR43270:SF16 BETA-ALA-HIS DIPEPTIDASE CYTOSOLIC NON-SPECIFIC DIPEPTIDASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000017196.1|UniProtKB=W5NKU6 W5NKU6 PTHR12537:SF52 RNA BINDING PROTEIN PUMILIO-RELATED PUMILIO HOMOLOG 2 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA metabolic process#GO:1903311;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013364.1|UniProtKB=W5N762 W5N762 PTHR34930:SF4 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000017340.1|UniProtKB=W5NLD6 W5NLD6 PTHR11214:SF29 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 9 glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000011993.1|UniProtKB=W5N297 W5N297 PTHR24103:SF337 E3 UBIQUITIN-PROTEIN LIGASE TRIM ZINC-BINDING PROTEIN A33-LIKE acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000000420.1|UniProtKB=W5LWF6 W5LWF6 PTHR18966:SF377 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1 transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;dicarboxylic acid transmembrane transporter activity#GO:0005310;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089 regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;regulation of biological quality#GO:0065008;glutamate receptor signaling pathway#GO:0007215;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NR1#P01010 LEPOC|Ensembl=ENSLOCG00000003982.1|UniProtKB=W5M8Q7 W5M8Q7 PTHR24061:SF651 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 3 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 sensory perception of taste#GO:0050909;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;system process#GO:0003008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011242.1|UniProtKB=W5MZK7 W5MZK7 PTHR14614:SF44 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN N-LYSINE METHYLTRANSFERASE METTL21D lysine N-methyltransferase activity#GO:0016278;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009718.1|UniProtKB=W5MU23 W5MU23 PTHR11977:SF30 VILLIN VILLIN-LIKE PROTEIN anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;actin filament binding#GO:0051015;actin binding#GO:0003779;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;phosphatidylinositol phosphate binding#GO:1901981 negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000001007.1|UniProtKB=W5LYC7 W5LYC7 PTHR23277:SF11 NECTIN-RELATED NECTIN-4 cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;adherens junction#GO:0005912;cell junction#GO:0030054 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004433.1|UniProtKB=W5MA87 W5MA87 PTHR23166:SF7 FILAMIN/GPBP-INTERACTING PROTEIN LEUCINE ZIPPER PROTEIN 1 intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000005621.1|UniProtKB=W5MEH6 W5MEH6 PTHR12035:SF125 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 5 organic acid binding#GO:0043177;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;carbohydrate derivative binding#GO:0097367 cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000000272.1|UniProtKB=W5LVZ0 W5LVZ0 PTHR10903:SF206 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000012808.1|UniProtKB=W5N552 W5N552 PTHR45924:SF4 FI17866P1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 3 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme binding#GO:0019899;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 regulation of establishment or maintenance of cell polarity#GO:0032878;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000013856.1|UniProtKB=W5N8Y0 W5N8Y0 PTHR45712:SF3 AGAP008170-PA OSTEOMODULIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014731.1|UniProtKB=W5NBX9 W5NBX9 PTHR21292:SF17 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN 2 ISOFORM X1 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cell cortex#GO:0005938 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013162.1|UniProtKB=W5N6F5 W5N6F5 PTHR11486:SF20 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 7 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;fibroblast growth factor receptor binding#GO:0005104;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;tube development#GO:0035295;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;response to fibroblast growth factor#GO:0071774;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 Fructose galactose metabolism#P02744>Galactokinase#P02960;FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000011756.1|UniProtKB=W5N1E9 W5N1E9 PTHR12064:SF22 METAL TRANSPORTER CNNM METAL TRANSPORTER CNNM2 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;magnesium ion transmembrane transporter activity#GO:0015095;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic ion homeostasis#GO:0050801;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000011320.1|UniProtKB=W5MZV8 W5MZV8 PTHR46021:SF3 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARFGAP WITH DUAL PH DOMAINS 1 phosphatidylinositol phosphate binding#GO:1901981;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;lipid binding#GO:0008289;molecular function activator activity#GO:0140677;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015657.1|UniProtKB=W5NF65 W5NF65 PTHR10183:SF409 CALPAIN CALPAIN-2 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000007144.1|UniProtKB=W5MJT7 W5MJT7 PTHR19969:SF8 SH2-SH3 ADAPTOR PROTEIN-RELATED ADAPTER MOLECULE CRK molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell migration#GO:0016477;cell motility#GO:0048870;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>CRK#P07125;Integrin signalling pathway#P00034>Crk#P00933;Angiogenesis#P00005>Crk#P00207 LEPOC|Ensembl=ENSLOCG00000010700.1|UniProtKB=W5MXJ9 W5MXJ9 PTHR23055:SF60 CALCIUM BINDING PROTEINS CALAXIN calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000009134.1|UniProtKB=W5MRX7 W5MRX7 PTHR42757:SF43 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED OBSCURIN, CYTOSKELETAL CALMODULIN AND TITIN-INTERACTING RHOGEF B heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000011744.1|UniProtKB=W5N1C8 W5N1C8 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 aspartic protease#PC00053;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000003520.1|UniProtKB=W5M732 W5M732 PTHR45858:SF2 FERM DOMAIN CONTAINING PROTEIN FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 1 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 LEPOC|Ensembl=ENSLOCG00000008734.1|UniProtKB=W5MQG9 W5MQG9 PTHR13546:SF14 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85C cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cell-cell junction#GO:0005911 LEPOC|Ensembl=ENSLOCG00000017895.1|UniProtKB=W5NMY9 W5NMY9 PTHR11521:SF23 TROPONIN T SLOW TROPONIN T protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;heart process#GO:0003015;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;system process#GO:0003008;heart contraction#GO:0060047;cellular developmental process#GO:0048869;muscle contraction#GO:0006936;developmental process#GO:0032502;striated muscle contraction#GO:0006941;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925 membraneless organelle#GO:0043228;sarcomere#GO:0030017;cytoskeleton#GO:0005856;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;contractile muscle fiber#GO:0043292;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000009581.1|UniProtKB=W5MTK4 W5MTK4 PTHR16029:SF11 CENTROSOMAL PROTEIN OF 192 KDA CENTROSOMAL PROTEIN OF 192 KDA organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;localization#GO:0051179;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;protein localization to centrosome#GO:0071539;protein localization to organelle#GO:0033365;mitotic cell cycle#GO:0000278;spindle organization#GO:0007051;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;protein localization to microtubule cytoskeleton#GO:0072698;nuclear division#GO:0000280;protein localization to microtubule organizing center#GO:1905508;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;protein localization to cytoskeleton#GO:0044380;sister chromatid segregation#GO:0000819;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;centrosome cycle#GO:0007098;mitotic spindle organization#GO:0007052;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005880.1|UniProtKB=W5MFE6 W5MFE6 PTHR43353:SF14 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Gamma-aminobutyric acid synthesis#P04384>Succinic semialdehyde dehydrogenase#P04481;Aminobutyrate degradation#P02726>Succinate semi-aldehyde dehydrogenase#P02824 LEPOC|Ensembl=ENSLOCG00000007949.1|UniProtKB=W5MMP8 W5MMP8 PTHR12411:SF856 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN S, ORTHOLOG 1 ISOFORM X1 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012193.1|UniProtKB=W5N2Y3 W5N2Y3 PTHR24369:SF156 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE RICH REPEAT AND IG DOMAIN CONTAINING 2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000448.1|UniProtKB=W5LWL9 W5LWL9 PTHR22796:SF14 URG4-RELATED INTERFERON-INDUCED VERY LARGE GTPASE 1-RELATED LEPOC|Ensembl=ENSLOCG00000000967.1|UniProtKB=W5LY81 W5LY81 PTHR23344:SF6 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 2 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;regulation of neuron differentiation#GO:0045664;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000018000.1|UniProtKB=W5NN92 W5NN92 PTHR24365:SF525 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 5 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;toll-like receptor signaling pathway#GO:0002224;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of innate immune response#GO:0045088;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009242.1|UniProtKB=W5MSB1 W5MSB1 PTHR24366:SF29 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN CONTAINING 5 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000013012.1|UniProtKB=W5N5X2 W5N5X2 PTHR24082:SF42 NUCLEAR HORMONE RECEPTOR THYROID HORMONE RECEPTOR ALPHA binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;intracellular receptor signaling pathway#GO:0030522;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;cellular response to chemical stimulus#GO:0070887;negative regulation of DNA-templated transcription#GO:0045892;hormone-mediated signaling pathway#GO:0009755;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;response to hormone#GO:0009725;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000005021.1|UniProtKB=W5MCD4 W5MCD4 PTHR39654:SF5 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 75A-LIKE ISOFORM X1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 75B LEPOC|Ensembl=ENSLOCG00000009698.1|UniProtKB=W5MTY2 W5MTY2 PTHR24339:SF25 HOMEOBOX PROTEIN EMX-RELATED HOMEOBOX PROTEIN EMX2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;head development#GO:0060322;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014822.1|UniProtKB=W5NC90 W5NC90 PTHR10032:SF273 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS OVO LIKE ZINC FINGER 3 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;epidermis development#GO:0008544;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013443.1|UniProtKB=W5N7G7 W5N7G7 PTHR45659:SF9 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000001341.1|UniProtKB=W5LZG7 W5LZG7 APIP PTHR10640:SF7 METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound metabolic process#GO:0006790;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000008688.1|UniProtKB=W5MQA7 W5MQA7 PTHR23507:SF9 ZGC:174356 LYSOSOMAL PROTON-COUPLED STEROID CONJUGATE AND BILE ACID SYMPORTER SLC46A3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;vacuolar transmembrane transport#GO:0034486;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000001102.1|UniProtKB=W5LYP6 W5LYP6 PTHR24185:SF10 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;olefinic compound metabolic process#GO:0120254;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;arachidonate metabolic process#GO:0019369;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid metabolic process#GO:0032787 membrane#GO:0016020;cellular anatomical structure#GO:0110165 phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010624.1|UniProtKB=W5MXD5 W5MXD5 PTHR24023:SF1123 COLLAGEN ALPHA COLLAGEN, TYPE XV, ALPHA 1B ISOFORM X1 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000004261.1|UniProtKB=W5M9N7 W5M9N7 PTHR24409:SF451 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 431-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000016226.1|UniProtKB=W5NH97 W5NH97 PTHR24351:SF184 RIBOSOMAL PROTEIN S6 KINASE SERINE_THREONINE-PROTEIN KINASE SGK1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002404.1|UniProtKB=W5M365 W5M365 PTHR10809:SF155 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;endoplasmic reticulum membrane organization#GO:0090158;neuron differentiation#GO:0030182;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000010138.1|UniProtKB=W5MVJ6 W5MVJ6 PTHR11588:SF494 TUBULIN TUBULIN ALPHA CHAIN guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085;tubulin#PC00228 LEPOC|Ensembl=ENSLOCG00000010481.1|UniProtKB=W5MWU0 W5MWU0 PTHR22923:SF96 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 3 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003464.1|UniProtKB=W5M6W5 W5M6W5 PTHR12385:SF42 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010553.1|UniProtKB=W5MX25 W5MX25 PTHR15451:SF19 ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000014575.1|UniProtKB=W5NBC9 W5NBC9 PTHR14083:SF1 YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN PROTEIN YIF1B endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134 LEPOC|Ensembl=ENSLOCG00000002159.1|UniProtKB=W5M2C8 W5M2C8 PTHR18916:SF10 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122;microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cell periphery#GO:0071944;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;microtubule end#GO:1990752;cell cortex#GO:0005938;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002166.1|UniProtKB=W5M2A9 W5M2A9 PTHR21446:SF6 DUF3504 DOMAIN-CONTAINING PROTEIN MITOCHONDRIAL ANTIVIRAL-SIGNALING PROTEIN LEPOC|Ensembl=ENSLOCG00000001018.1|UniProtKB=W5LYH7 W5LYH7 PTHR23103:SF14 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID BETA PRECURSOR LIKE PROTEIN 2 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron projection development#GO:0031175;axon development#GO:0061564;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000003741.1|UniProtKB=W5M7U7 W5M7U7 PTHR12863:SF23 FATTY ACID HYDROXYLASE FATTY ACID 2-HYDROXYLASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 cellular process#GO:0009987;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;biosynthetic process#GO:0009058;nervous system development#GO:0007399;lipid biosynthetic process#GO:0008610;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;oligodendrocyte differentiation#GO:0048709;developmental process#GO:0032502;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;gliogenesis#GO:0042063;neurogenesis#GO:0022008;myelination#GO:0042552;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cell development#GO:0048468;central nervous system development#GO:0007417;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;plasma membrane organization#GO:0007009;ceramide metabolic process#GO:0006672;anatomical structure development#GO:0048856 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydroxylase#PC00122;oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017623.1|UniProtKB=W5NM69 W5NM69 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010620.1|UniProtKB=W5MXA0 W5MXA0 PTHR12363:SF33 TRANSPORTIN 3 AND IMPORTIN 13 IMPORTIN-13 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010383.1|UniProtKB=W5MWH1 W5MWH1 PTHR14038:SF6 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2C RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000854.1|UniProtKB=W5LXU1 W5LXU1 PTHR13452:SF10 THUMP DOMAIN CONTAINING PROTEIN 1-RELATED THUMP DOMAIN-CONTAINING PROTEIN 1 protein-RNA adaptor activity#GO:0140517;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 LEPOC|Ensembl=ENSLOCG00000014962.1|UniProtKB=W5NCR4 W5NCR4 PTHR10502:SF28 ANNEXIN ANNEXIN A4 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phospholipid binding#GO:0005543;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;vesicle#GO:0031982;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000000179.1|UniProtKB=W5LVP3 W5LVP3 PTHR46890:SF1 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED SECRETED RXLR EFFECTOR PROTEIN 78-LIKE viral or transposable element protein#PC00237;reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000016058.1|UniProtKB=W5NGM4 W5NGM4 PTHR14195:SF4 G PATCH DOMAIN CONTAINING PROTEIN 2 G PATCH DOMAIN-CONTAINING PROTEIN 2 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000002408.1|UniProtKB=W5M383 W5M383 PTHR13798:SF12 RNA BINDING MOTIF RBM PROTEIN -RELATED RNA BINDING MOTIF PROTEIN 11-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008475.1|UniProtKB=W5MPL4 W5MPL4 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000164.1|UniProtKB=W5LVM4 W5LVM4 PTHR24230:SF31 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 1 neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;neuropeptide signaling pathway#GO:0007218;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006055.1|UniProtKB=W5MG07 W5MG07 PTHR23333:SF47 UBX DOMAIN CONTAINING PROTEIN NSFL1 COFACTOR P47 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;establishment of spindle localization#GO:0051293;positive regulation of cellular process#GO:0048522;microtubule cytoskeleton organization#GO:0000226;protein metabolic process#GO:0019538;localization#GO:0051179;organelle localization#GO:0051640;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;primary metabolic process#GO:0044238;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;modification-dependent protein catabolic process#GO:0019941;establishment of cell polarity#GO:0030010;cellular component organization or biogenesis#GO:0071840;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;spindle localization#GO:0051653;cellular localization#GO:0051641;establishment or maintenance of cell polarity#GO:0007163;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;establishment of organelle localization#GO:0051656;regulation of cell cycle#GO:0051726;cellular component organization#GO:0016043;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000017533.1|UniProtKB=W5NLX9 W5NLX9 PTHR28644:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 15 SMALL INTEGRAL MEMBRANE PROTEIN 15 LEPOC|Ensembl=ENSLOCG00000007699.1|UniProtKB=W5MLU0 W5MLU0 PTHR10429:SF0 DNA-3-METHYLADENINE GLYCOSYLASE DNA-3-METHYLADENINE GLYCOSYLASE catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA N-glycosylase activity#GO:0019104 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 LEPOC|Ensembl=ENSLOCG00000005475.1|UniProtKB=W5MDZ6 W5MDZ6 PTHR12493:SF0 CUE DOMAIN CONTAINING 2 CUE DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000009818.1|UniProtKB=W5MUD4 W5MUD4 PTHR10912:SF9 ADP-RIBOSYL CYCLASE ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;cyclase#PC00079 LEPOC|Ensembl=ENSLOCG00000016780.1|UniProtKB=W5NJD3 W5NJD3 PTHR43851:SF1 FAMILY NOT NAMED ATYPICAL KINASE COQ8A, MITOCHONDRIAL small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 LEPOC|Ensembl=ENSLOCG00000002674.1|UniProtKB=W5M477 W5M477 PTHR11616:SF263 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 1 monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;import into cell#GO:0098657;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;monoatomic cation transport#GO:0006812;localization#GO:0051179;glycine transport#GO:0015816 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000009455.1|UniProtKB=W5MT34 W5MT34 PTHR12345:SF14 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 1 binding#GO:0005488;peptide binding#GO:0042277 synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell junction#GO:0030054;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic tree#GO:0097447;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093;Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084 LEPOC|Ensembl=ENSLOCG00000010956.1|UniProtKB=W5MYI6 W5MYI6 PTHR22847:SF753 WD40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 55 HOMOLOG LEPOC|Ensembl=ENSLOCG00000003851.1|UniProtKB=W5M888 W5M888 PTHR11003:SF75 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 9 transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 5HT3 type receptor mediated signaling pathway#P04375>K+ channel#P04425;Dopamine receptor mediated signaling pathway#P05912>K+ channel#P05957;Opioid proenkephalin pathway#P05915>K+ channel#P05990;Nicotine pharmacodynamics pathway#P06587>KCNK3/9#P06605;5HT4 type receptor mediated signaling pathway#P04376>K+ channel#P04426;Opioid proopiomelanocortin pathway#P05917>K+ channel#P06009;5HT1 type receptor mediated signaling pathway#P04373>K+ channel#P04407;5HT2 type receptor mediated signaling pathway#P04374>K+ channel#P04413 LEPOC|Ensembl=ENSLOCG00000011255.1|UniProtKB=W5MZM1 W5MZM1 PTHR45710:SF36 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016813.1|UniProtKB=W5NJI4 W5NJI4 PTHR24351:SF213 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;TOR signaling#GO:0031929;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;TORC1 signaling#GO:0038202 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;Interleukin signaling pathway#P00036>p90RSK#P00964;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Ras Pathway#P04393>p90RSK#P04541 LEPOC|Ensembl=ENSLOCG00000017055.1|UniProtKB=W5NKC4 W5NKC4 PTHR16130:SF3 LYSOSOMAL COBALAMIN TRANSPORTER-RELATED LYSOSOMAL COBALAMIN TRANSPORT ESCORT PROTEIN LMBD1 protein localization to vacuole#GO:0072665;macromolecule localization#GO:0033036;protein localization to lysosome#GO:0061462;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009410.1|UniProtKB=W5MSX8 W5MSX8 PTHR12942:SF2 STEP II SPLICING FACTOR SLU7 PRE-MRNA-SPLICING FACTOR SLU7 binding#GO:0005488;nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000012666.1|UniProtKB=W5N4M8 W5N4M8 PTHR11937:SF370 ACTIN ALPHA-CENTRACTIN cytoskeletal adaptor activity#GO:0008093;structural constituent of cytoskeleton#GO:0005200;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495;structural molecule activity#GO:0005198 organelle localization#GO:0051640;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;nuclear migration#GO:0007097;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384 microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 LEPOC|Ensembl=ENSLOCG00000009374.1|UniProtKB=W5MST6 W5MST6 PTHR24213:SF0 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 3 binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cell projection assembly#GO:0030031;lamellipodium assembly#GO:0030032;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641;actin filament bundle#GO:0032432;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;stress fiber#GO:0001725;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000017945.1|UniProtKB=W5NN39 W5NN39 PTHR20899:SF4 PIERCE HOMOLOG PIERCER OF MICROTUBULE WALL 2 PROTEIN LEPOC|Ensembl=ENSLOCG00000003233.1|UniProtKB=W5M628 W5M628 PTHR16517:SF20 TUBBY-RELATED TUBBY PROTEIN HOMOLOG macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein localization to cilium#GO:0061512;localization#GO:0051179;protein localization to organelle#GO:0033365 cilium#GO:0005929;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000728.1|UniProtKB=W5LXE9 W5LXE9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016436.1|UniProtKB=W5NI43 W5NI43 PTHR24042:SF0 NEL HOMOLOG PROTEIN KINASE C-BINDING PROTEIN NELL2 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;glycosaminoglycan binding#GO:0005539;protein binding#GO:0005515;heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000004913.1|UniProtKB=W5MC02 W5MC02 PTHR11062:SF8 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 1 hexosyltransferase activity#GO:0016758;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000006403.1|UniProtKB=W5MH77 W5MH77 PTHR11937:SF16 ACTIN ACTIN-RELATED PROTEIN 5 molecular function regulator activity#GO:0098772;structural molecule activity#GO:0005198;enzyme regulator activity#GO:0030234;structural constituent of cytoskeleton#GO:0005200 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;Ino80 complex#GO:0031011;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346 actin and actin related protein#PC00039 LEPOC|Ensembl=ENSLOCG00000011619.1|UniProtKB=W5N0X0 W5N0X0 PTHR14383:SF2 SWAP-70 RECOMBINASE DIFFERENTIALLY EXPRESSED IN FDCP 6 HOMOLOG enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component assembly#GO:0022607;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;response to stimulus#GO:0050896;actin filament polymerization#GO:0030041;signaling#GO:0023052;actin filament-based process#GO:0030029;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;supramolecular fiber organization#GO:0097435 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;actin cytoskeleton#GO:0015629;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016743.1|UniProtKB=W5NJ87 W5NJ87 PTHR22771:SF2 CULLIN AND GALACTOSE-BINDING DOMAIN-CONTAINING CULLIN-9 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of mitotic nuclear division#GO:0007088;macromolecule metabolic process#GO:0043170;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of nuclear division#GO:0051783;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;regulation of organelle organization#GO:0033043;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000003711.1|UniProtKB=W5M7V3 W5M7V3 PTHR11557:SF0 PORPHOBILINOGEN DEAMINASE PORPHOBILINOGEN DEAMINASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound biosynthetic process#GO:0006779;cellular process#GO:0009987;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 deaminase#PC00088;metabolite interconversion enzyme#PC00262 Heme biosynthesis#P02746>Hydroxymethylbilane synthase#P02983 LEPOC|Ensembl=ENSLOCG00000014829.1|UniProtKB=W5NCA1 W5NCA1 PTHR23099:SF0 TRANSCRIPTIONAL REGULATOR GERM CELL NUCLEAR ACIDIC PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000001670.1|UniProtKB=W5M0L8 W5M0L8 PTHR23088:SF27 NITRILASE-RELATED DEAMINATED GLUTATHIONE AMIDASE hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008861.1|UniProtKB=W5MQX7 W5MQX7 PTHR44984:SF1 SERINE/THREONINE-PROTEIN KINASE NEK3 SERINE_THREONINE-PROTEIN KINASE NEK3 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010571.1|UniProtKB=W5MX43 W5MX43 PTHR11280:SF8 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE DEAMINASE 1 catalytic activity#GO:0003824;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;identical protein binding#GO:0042802;deaminase activity#GO:0019239 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;amino sugar catabolic process#GO:0046348;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 isomerase#PC00135 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 LEPOC|Ensembl=ENSLOCG00000008473.1|UniProtKB=W5MPK2 W5MPK2 PTHR34917:SF1 RBPJ-INTERACTING AND TUBULIN-ASSOCIATED PROTEIN 1 RBPJ-INTERACTING AND TUBULIN-ASSOCIATED PROTEIN 1 binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;negative regulation of cell communication#GO:0010648;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;negative regulation of Notch signaling pathway#GO:0045746;regulation of response to stimulus#GO:0048583;transport#GO:0006810;establishment of localization#GO:0051234 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000000247.1|UniProtKB=W5LVW4 W5LVW4 PTHR11461:SF53 SERINE PROTEASE INHIBITOR, SERPIN ANTITHROMBIN-III extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Blood coagulation#P00011>ATIII#P00440 LEPOC|Ensembl=ENSLOCG00000015269.1|UniProtKB=W5NDS9 W5NDS9 PTHR10704:SF66 CARBOHYDRATE SULFOTRANSFERASE SULFOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;amino sugar metabolic process#GO:0006040 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000001842.1|UniProtKB=W5M195 W5M195 PTHR24370:SF10 OPTICIN LEUCINE-RICH REPEAT AND WD REPEAT-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000013383.1|UniProtKB=W5N788 W5N788 PTHR23268:SF31 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 30 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000011847.1|UniProtKB=W5N1R2 W5N1R2 PTHR45615:SF88 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-16 polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000015057.1|UniProtKB=W5ND24 W5ND24 PTHR10829:SF12 CORTACTIN AND DREBRIN DREBRIN-LIKE PROTEIN binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064 cell leading edge#GO:0031252;neuron projection#GO:0043005;cell periphery#GO:0071944;lamellipodium#GO:0030027;supramolecular complex#GO:0099080;glutamatergic synapse#GO:0098978;supramolecular polymer#GO:0099081;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;actin filament#GO:0005884;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000012850.1|UniProtKB=W5N5A5 W5N5A5 PTHR24055:SF25 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 4 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell surface receptor signaling pathway#GO:0007166 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099 LEPOC|Ensembl=ENSLOCG00000009205.1|UniProtKB=W5MS74 W5MS74 PTHR45622:SF73 UBIQUITIN-PROTEIN LIGASE E3A-RELATED HECT DOMAIN-CONTAINING PROTEIN acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000000631.1|UniProtKB=W5LX44 W5LX44 PTHR14396:SF10 CLASPIN CLASPIN LEPOC|Ensembl=ENSLOCG00000004478.1|UniProtKB=W5MAF6 W5MAF6 PTHR12205:SF0 CENTROMERE/KINETOCHORE PROTEIN ZW10 CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;transport#GO:0006810;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;regulation of mitotic sister chromatid segregation#GO:0033047;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;vesicle-mediated transport#GO:0016192;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;negative regulation of cell cycle phase transition#GO:1901988;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;nuclear division#GO:0000280;cellular localization#GO:0051641;regulation of mitotic cell cycle#GO:0007346;mitotic sister chromatid segregation#GO:0000070;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;establishment of localization#GO:0051234;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of chromosome organization#GO:2001251;intracellular signal transduction#GO:0035556;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;organelle fission#GO:0048285;cell communication#GO:0007154;localization#GO:0051179;mitotic spindle assembly checkpoint signaling#GO:0007094;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;Golgi vesicle transport#GO:0048193;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;negative regulation of cell cycle#GO:0045786;cellular component organization#GO:0016043;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990 microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;spindle#GO:0005819;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;endoplasmic reticulum#GO:0005783;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;vesicle tethering complex#GO:0099023;endoplasmic reticulum protein-containing complex#GO:0140534;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000020990.1|UniProtKB=Q8HQM6 Q8HQM6 PTHR11058:SF26 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;electron transfer activity#GO:0009055;NADH dehydrogenase activity#GO:0003954 respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001255.1|UniProtKB=W5LZD1 W5LZD1 PTHR13817:SF77 TITIN CONTACTIN 1 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016318.1|UniProtKB=W5NHN3 W5NHN3 PTHR12268:SF22 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROBREVIN BETA animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;cellular process#GO:0009987;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008464.1|UniProtKB=W5MPJ3 W5MPJ3 PTHR12011:SF59 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR L4 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010757.1|UniProtKB=W5MXS1 W5MXS1 PTHR11329:SF1 LEUKOCYTE CELL-DERIVED CHEMOTAXIN 2 LEUKOCYTE CELL-DERIVED CHEMOTAXIN-2-LIKE ISOFORM X1 chemokine#PC00074;cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000015841.1|UniProtKB=W5NFU1 W5NFU1 PTHR24028:SF262 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 3 cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000001262.1|UniProtKB=W5LZ83 W5LZ83 PTHR24390:SF230 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 362 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000007312.1|UniProtKB=W5MKF2 W5MKF2 PTHR11830:SF15 40S RIBOSOMAL PROTEIN S3A UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;structural constituent of ribosome#GO:0003735;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;structural molecule activity#GO:0005198 gene expression#GO:0010467;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;necroptotic process#GO:0070266;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;protein biosynthetic process#GO:0160307;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;regulation of programmed cell death#GO:0043067;protein modification process#GO:0036211;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cell death#GO:0008219;regulation of intrinsic apoptotic signaling pathway#GO:2001242;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;regulation of intracellular signal transduction#GO:1902531;translation#GO:0006412;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000011354.1|UniProtKB=W5MZZ5 W5MZZ5 PTHR23235:SF56 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 12 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000003579.1|UniProtKB=W5M782 W5M782 PTHR25466:SF21 T-LYMPHOCYTE ACTIVATION ANTIGEN BUTYROPHILIN SUBFAMILY 2 MEMBER A1-LIKE-RELATED molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012868.1|UniProtKB=W5N5D1 W5N5D1 PTHR46221:SF14 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000003441.1|UniProtKB=W5M6S4 W5M6S4 PTHR16019:SF6 SYNAPSE-ASSOCIATED PROTEIN SYNAPSE-ASSOCIATED PROTEIN 1 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of fat cell differentiation#GO:0045600;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;TORC2 signaling#GO:0038203;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;TOR signaling#GO:0031929;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;synapse#GO:0045202;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000002726.1|UniProtKB=W5M494 W5M494 PTHR24399:SF19 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 20 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000005859.1|UniProtKB=W5MFB6 W5MFB6 PTHR10766:SF188 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 4 protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;localization within membrane#GO:0051668;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014296.1|UniProtKB=W5NAE1 W5NAE1 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009280.1|UniProtKB=W5MSG0 W5MSG0 PTHR10613:SF0 LEUKOCYTE SURFACE ANTIGEN CD47 LEUKOCYTE SURFACE ANTIGEN CD47 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002376.1|UniProtKB=W5M345 W5M345 PTHR12791:SF37 GOLGI SNARE BET1-RELATED BET1-LIKE PROTEIN SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization#GO:0051179;cellular localization#GO:0051641;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cytosolic transport#GO:0016482;regulation of cellular process#GO:0050794;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;regulation of transport#GO:0051049;regulation of localization#GO:0032879;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000012294.1|UniProtKB=W5N3B6 W5N3B6 PTHR24300:SF364 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;binding#GO:0005488 primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;steroid metabolic process#GO:0008202;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001702.1|UniProtKB=W5M0R2 W5M0R2 PTHR15592:SF19 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011740.1|UniProtKB=W5N1E0 W5N1E0 PTHR19143:SF444 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-3 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000007797.1|UniProtKB=W5MM59 W5MM59 PTHR10098:SF108 RAPSYN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 28 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005583.1|UniProtKB=W5MEF7 W5MEF7 PTHR23005:SF4 RETINITIS PIGMENTOSA 1 PROTEIN OXYGEN-REGULATED PROTEIN 1 cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cilium organization#GO:0044782;neuron development#GO:0048666;eye development#GO:0001654;cellular process#GO:0009987;cell projection assembly#GO:0030031;sensory system development#GO:0048880;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;retina development in camera-type eye#GO:0060041;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;anatomical structure homeostasis#GO:0060249;cellular component assembly#GO:0022607;neuron differentiation#GO:0030182;microtubule-based process#GO:0007017;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;visual system development#GO:0150063;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;camera-type eye development#GO:0043010;tissue homeostasis#GO:0001894;system development#GO:0048731;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;retina homeostasis#GO:0001895;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031;multicellular organismal-level homeostasis#GO:0048871;neurogenesis#GO:0022008;cellular developmental process#GO:0048869 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;ciliary transition zone#GO:0035869;intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000001905.1|UniProtKB=W5M1G9 W5M1G9 PTHR43226:SF1 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO DIPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000014286.1|UniProtKB=W5NAD3 W5NAD3 PTHR15435:SF2 KICSTOR COMPLEX PROTEIN KAPTIN KICSTOR COMPLEX PROTEIN KAPTIN binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to nutrient levels#GO:0031667;response to stress#GO:0006950;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;negative regulation of response to stimulus#GO:0048585;cellular response to nutrient levels#GO:0031669;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell leading edge#GO:0031252 LEPOC|Ensembl=ENSLOCG00000005615.1|UniProtKB=W5MEG8 W5MEG8 PTHR46605:SF1 TUMOR NECROSIS FACTOR RECEPTOR DEATH DOMAIN-CONTAINING MEMBRANE PROTEIN NRADD death receptor activity#GO:0005035;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;growth factor binding#GO:0019838;coreceptor activity#GO:0015026;signaling receptor activity#GO:0038023 Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015222.1|UniProtKB=W5NDM3 W5NDM3 PTHR13005:SF2 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN CYSTEINE-RICH HYDROPHOBIC DOMAIN-CONTAINING PROTEIN 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011928.1|UniProtKB=W5N206 W5N206 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED reverse transcriptase#PC00200;viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000014723.1|UniProtKB=W5NBW8 W5NBW8 PTHR10083:SF384 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED KUNITZ-TYPE PROTEASE INHIBITOR 2 PRECURSOR molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000010587.1|UniProtKB=W5MX79 W5MX79 PTHR45652:SF2 GLIAL FIBRILLARY ACIDIC PROTEIN DESMIN structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization#GO:0016043;intermediate filament cytoskeleton organization#GO:0045104;muscle structure development#GO:0061061;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;muscle organ development#GO:0007517;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell-cell junction#GO:0005911;membrane#GO:0016020;contractile muscle fiber#GO:0043292;cell periphery#GO:0071944;Z disc#GO:0030018;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;I band#GO:0031674;cell junction#GO:0030054;sarcolemma#GO:0042383;sarcomere#GO:0030017;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intermediate filament#GO:0005882 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000001936.1|UniProtKB=W5M1K4 W5M1K4 PTHR43778:SF4 PYRUVATE CARBOXYLASE PYRUVATE CARBOXYLASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular process#GO:0009987;hexose biosynthetic process#GO:0019319;gluconeogenesis#GO:0006094;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glucose metabolic process#GO:0006006 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ligase#PC00142;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Pyruvate Carboxylase#P03140 LEPOC|Ensembl=ENSLOCG00000012736.1|UniProtKB=W5N4V8 W5N4V8 PTHR23138:SF186 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3-RELATED intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179 membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle envelope#GO:0031967 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009616.1|UniProtKB=W5MTP9 W5MTP9 PTHR15398:SF4 BROMODOMAIN-CONTAINING PROTEIN 8 BROMODOMAIN-CONTAINING PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000007537.1|UniProtKB=W5ML84 W5ML84 PTHR16048:SF3 MSL2-RELATED E3 UBIQUITIN-PROTEIN LIGASE MSL2 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000014191.1|UniProtKB=W5NA22 W5NA22 PTHR12027:SF33 WNT RELATED PROTEIN WNT-5A protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664 cell differentiation#GO:0030154;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;cell fate commitment#GO:0045165;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206 LEPOC|Ensembl=ENSLOCG00000010983.1|UniProtKB=W5MYL1 W5MYL1 PTHR12170:SF2 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000017580.1|UniProtKB=W5NM26 W5NM26 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H6 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009597.1|UniProtKB=W5MTL6 W5MTL6 PTHR11902:SF30 ENOLASE ENOLASE 4 phosphopyruvate hydratase activity#GO:0004634;catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496 cytosol#GO:0005829;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000000315.1|UniProtKB=W5LW34 W5LW34 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012421.1|UniProtKB=W5N3T3 W5N3T3 PTHR33820:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 LEPOC|Ensembl=ENSLOCG00000013323.1|UniProtKB=W5N711 W5N711 PTHR17388:SF2 SECRETOGRANIN III SECRETOGRANIN-3 macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365 vesicle#GO:0031982;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000007611.1|UniProtKB=W5MLH5 W5MLH5 PTHR31993:SF5 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 UBA-LIKE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000000026.1|UniProtKB=W5LV73 W5LV73 PTHR24115:SF534 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF20B pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000012551.1|UniProtKB=W5N499 W5N499 PTHR43908:SF2 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 18 Hsp70 protein binding#GO:0030544;protein binding#GO:0005515;heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;cellular response to misfolded protein#GO:0071218;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;response to misfolded protein#GO:0051788;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000014503.1|UniProtKB=W5NB44 W5NB44 PTHR13027:SF13 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG B guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;late endosome#GO:0005770;guanyl-nucleotide exchange factor complex#GO:0032045;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000015485.1|UniProtKB=W5NEK0 W5NEK0 PTHR12497:SF8 TAZ PROTEIN TAFAZZIN TAFAZZIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;glycerophospholipid metabolic process#GO:0006650;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000018087.1|UniProtKB=W5NNH9 W5NNH9 PTHR24225:SF50 CHEMOTACTIC RECEPTOR PROSTAGLANDIN D2 RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;immune system process#GO:0002376;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011095.1|UniProtKB=W5MZ20 W5MZ20 PTHR15893:SF17 RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000003596.1|UniProtKB=W5M7A4 W5M7A4 PTHR18952:SF25 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 5B, MITOCHONDRIAL catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006718.1|UniProtKB=W5MIB0 W5MIB0 PTHR23503:SF22 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 11 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;import across plasma membrane#GO:0098739;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000007772.1|UniProtKB=W5MM34 W5MM34 PTHR19850:SF31 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-3 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor complex adaptor activity#GO:0030159 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622 heterotrimeric G-protein#PC00117;G-protein#PC00020;protein-binding activity modulator#PC00095 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Enkephalin release#P05913>G-Protein (i)#P05974;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;GABA-B receptor II signaling#P05731>Gbeta#P05755;Enkephalin release#P05913>G-Protein (s)#P05977;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;PI3 kinase pathway#P00048>Gbetagamma#P01188;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Wnt signaling pathway#P00057>GBeta#P01457;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743 LEPOC|Ensembl=ENSLOCG00000001220.1|UniProtKB=W5LZ20 W5LZ20 PTHR22750:SF2 G-PROTEIN COUPLED RECEPTOR MELANOCYTE-STIMULATING HORMONE RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;phenol-containing compound biosynthetic process#GO:0046189;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;melanin biosynthetic process#GO:0042438;phenol-containing compound metabolic process#GO:0018958;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of response to stimulus#GO:0048583;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;pigment biosynthetic process#GO:0046148;positive regulation of intracellular signal transduction#GO:1902533;secondary metabolic process#GO:0019748;pigment metabolic process#GO:0042440;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;cell communication#GO:0007154;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015120.1|UniProtKB=W5ND97 W5ND97 PTHR15950:SF23 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN SI:CH73-52F15.5-RELATED regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000006465.1|UniProtKB=W5MHF1 W5MHF1 PTHR15811:SF5 MTH938 DOMAIN-CONTAINING PROTEIN MTH938 DOMAIN-CONTAINING PROTEIN positive regulation of fat cell differentiation#GO:0045600;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000003116.1|UniProtKB=W5M5L5 W5M5L5 PTHR22961:SF16 SER/THR PROTEIN KINASE-TRB SERINE_THREONINE-PROTEIN KINASE 40 regulation of intracellular signal transduction#GO:1902531;regulation of MAPK cascade#GO:0043408;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000014579.1|UniProtKB=W5NBD2 W5NBD2 PTHR12306:SF9 CELL DEATH ACTIVATOR CIDE LIPID TRANSFERASE CIDEC lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;lipid transfer activity#GO:0120013 lipid droplet organization#GO:0034389;cellular component organization or biogenesis#GO:0071840;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987;lipid storage#GO:0019915;cellular component organization#GO:0016043;programmed cell death#GO:0012501;organelle organization#GO:0006996;organelle fusion#GO:0048284 membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011841.1|UniProtKB=W5N1Q1 W5N1Q1 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 ISOFORM X1 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017444.1|UniProtKB=W5NLP0 W5NLP0 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN LOW QUALITY PROTEIN: ODORANT RECEPTOR 125-6-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010230.1|UniProtKB=W5MVW9 W5MVW9 PTHR45619:SF81 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT ALPHA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 cell cycle#GO:0007049;cellular process#GO:0009987;mitotic cell cycle#GO:0000278 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>PP2A-C#P04659;Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643;p53 pathway#P00059>PP2A#P04630;EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000017190.1|UniProtKB=W5NKT6 W5NKT6 PTHR47130:SF3 SI:DKEY-19B23.11-RELATED ZONA PELLUCIDA PROTEIN LEPOC|Ensembl=ENSLOCG00000011958.1|UniProtKB=W5N250 W5N250 PTHR15706:SF30 SH3 MULTIPLE DOMAIN SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;superoxide metabolic process#GO:0006801 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014458.1|UniProtKB=W5NAZ7 W5NAZ7 PTHR10606:SF14 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE 4 transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;kinase activity#GO:0016301;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;phosphoric ester hydrolase activity#GO:0042578;sugar-phosphatase activity#GO:0050308;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181;carbohydrate phosphatase#PC00066;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016826.1|UniProtKB=W5NJI9 W5NJI9 PTHR14209:SF19 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000004143.1|UniProtKB=W5M9A0 W5M9A0 PTHR12150:SF14 CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED 28S RRNA (URIDINE-N(3))-METHYLTRANSFERASE binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 localization#GO:0051179;organelle localization#GO:0051640;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;centrosome localization#GO:0051642;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558 cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitotic spindle#GO:0072686;chromosome#GO:0005694;spindle pole#GO:0000922;kinetochore#GO:0000776;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000009329.1|UniProtKB=W5MSM1 W5MSM1 PTHR21324:SF13 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED SI:DKEY-228D14.5 localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013436.1|UniProtKB=W5N7F8 W5N7F8 PTHR45664:SF11 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B3 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anterior/posterior pattern specification#GO:0009952;embryo development#GO:0009790;skeletal system development#GO:0001501;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;skeletal system morphogenesis#GO:0048705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000017384.1|UniProtKB=W5NLI0 W5NLI0 PTHR45773:SF6 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 3 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;positive regulation of cellular component biogenesis#GO:0044089;regulation of multicellular organismal process#GO:0051239;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;regulation of synapse organization#GO:0050807;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;positive regulation of nervous system development#GO:0051962;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;cell development#GO:0048468;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of synapse assembly#GO:0051965;neuron projection morphogenesis#GO:0048812;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;system development#GO:0048731;regulation of cell junction assembly#GO:1901888;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793 synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;GABA-ergic synapse#GO:0098982;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004120.1|UniProtKB=W5M968 W5M968 PTHR12113:SF8 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 3 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;signaling receptor inhibitor activity#GO:0030547;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;binding#GO:0005488 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004501.1|UniProtKB=W5MAH0 W5MAH0 PTHR24404:SF33 ZINC FINGER PROTEIN ZINC FINGER PROTEIN HELIOS double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002913.1|UniProtKB=W5M4W3 W5M4W3 PTHR10105:SF4 SELENOPROTEIN P SELENOPROTEIN P2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000015081.1|UniProtKB=W5ND53 W5ND53 PTHR11783:SF274 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4A1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000001994.1|UniProtKB=W5M1P6 W5M1P6 PTHR24006:SF747 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000009142.1|UniProtKB=W5MRY6 W5MRY6 PTHR46321:SF1 KIF1-BINDING PROTEIN KIF-BINDING PROTEIN nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;neuron projection organization#GO:0106027;central nervous system development#GO:0007417;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon development#GO:0061564;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;system development#GO:0048731;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226 LEPOC|Ensembl=ENSLOCG00000015614.1|UniProtKB=W5NF12 W5NF12 MAL PTHR22776:SF12 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MYELIN AND LYMPHOCYTE PROTEIN structural molecule activity#GO:0005198 protein insertion into membrane#GO:0051205;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;membrane organization#GO:0061024;nervous system development#GO:0007399;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;myelination#GO:0042552;developmental process#GO:0032502;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;localization#GO:0051179;anatomical structure development#GO:0048856;cellular localization#GO:0051641;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;localization within membrane#GO:0051668 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;membrane raft#GO:0045121;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane microdomain#GO:0098857 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013024.1|UniProtKB=W5N5Y0 W5N5Y0 PTHR14647:SF57 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 4 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011321.1|UniProtKB=W5MZU9 W5MZU9 PTHR16267:SF13 BANK1/PIK3AP1 FAMILY MEMBER B-CELL SCAFFOLD PROTEIN WITH ANKYRIN REPEATS enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;negative regulation of cell activation#GO:0050866;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;leukocyte activation#GO:0045321;negative regulation of multicellular organismal process#GO:0051241;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;cell activation#GO:0001775;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;lymphocyte activation#GO:0046649;cellular process#GO:0009987;regulation of B cell activation#GO:0050864;B cell activation#GO:0042113;regulation of lymphocyte activation#GO:0051249;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;immune system process#GO:0002376 LEPOC|Ensembl=ENSLOCG00000010709.1|UniProtKB=W5MXK9 W5MXK9 PTHR12274:SF7 GRANULIN GRANULINS-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014592.1|UniProtKB=W5NBE8 W5NBE8 PTHR22792:SF71 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 6 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011362.1|UniProtKB=W5N013 W5N013 PTHR11610:SF199 LIPASE PANCREATIC TRIACYLGLYCEROL LIPASE-LIKE ISOFORM X2 hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000005311.1|UniProtKB=W5MDD9 W5MDD9 PTHR24056:SF233 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 9 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000005073.1|UniProtKB=W5MCM5 W5MCM5 PTHR12394:SF4 ZYGIN FASCICULATION AND ELONGATION PROTEIN ZETA-1 axon#GO:0030424;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003610.1|UniProtKB=W5M7C4 W5M7C4 PTHR10383:SF22 SERINE INCORPORATOR SERINE INCORPORATOR 2 cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000011799.1|UniProtKB=W5N1K4 W5N1K4 PTHR19879:SF4 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;peptidase complex#GO:1905368;transferase complex#GO:1990234;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;SAGA-type complex#GO:0070461;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transcription factor TFIID complex#GO:0005669;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493 LEPOC|Ensembl=ENSLOCG00000011548.1|UniProtKB=W5N0N0 W5N0N0 PTHR24214:SF5 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 heart development#GO:0007507;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental process#GO:0032502;circulatory system development#GO:0072359;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029 cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;actin filament bundle#GO:0032432;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell-cell junction#GO:0005911;Z disc#GO:0030018;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;stress fiber#GO:0001725;actin filament#GO:0005884;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000017471.1|UniProtKB=W5NLR7 W5NLR7 PTHR24228:SF8 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR TYPE-2 ANGIOTENSIN II RECEPTOR G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;regulation of biological quality#GO:0065008;circulatory system process#GO:0003013;G protein-coupled receptor signaling pathway#GO:0007186;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;vasodilation#GO:0042311;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;defense response#GO:0006952;system process#GO:0003008;regulation of anatomical structure size#GO:0090066;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013604.1|UniProtKB=W5N818 W5N818 PTHR10658:SF55 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CYTOPLASMIC PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 1 cation binding#GO:0043169;intramembrane lipid carrier activity#GO:0140303;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylcholine intramembrane carrier activity#GO:0008525;ion binding#GO:0043167;lipid carrier activity#GO:0005319;phosphatidylinositol transfer activity#GO:0008526;phosphatidylcholine binding#GO:0031210;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;binding#GO:0005488;molecular carrier activity#GO:0140104;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007120.1|UniProtKB=W5MJR2 W5MJR2 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011209.1|UniProtKB=W5MZG6 W5MZG6 PTHR11987:SF4 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8E glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000003567.1|UniProtKB=W5M772 W5M772 PTHR14167:SF6 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING KINASE-BINDING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012499.1|UniProtKB=W5N426 W5N426 PTHR13341:SF4 MIR-INTERACTING SAPOSIN-LIKE PROTEIN CANOPY FGF SIGNALING REGULATOR 1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000017200.1|UniProtKB=W5NKV4 W5NKV4 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000000459.1|UniProtKB=W5LWJ4 W5LWJ4 PTHR24242:SF359 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H6 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007869.1|UniProtKB=W5MME9 W5MME9 PTHR46256:SF1 AGAP011099-PA MYOSIN-IIIB protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;ATP-dependent activity#GO:0140657;protein serine/threonine kinase activity#GO:0004674;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;macromolecular conformation isomerase activity#GO:0120543;kinase activity#GO:0016301;microfilament motor activity#GO:0000146;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;regulation of plasma membrane bounded cell projection organization#GO:0120035;system process#GO:0003008;regulation of filopodium assembly#GO:0051489;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;positive regulation of cell projection organization#GO:0031346;regulation of cell projection assembly#GO:0060491;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;nervous system process#GO:0050877;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;sensory perception of sound#GO:0007605;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087 actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;filopodium#GO:0030175;photoreceptor inner segment#GO:0001917;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;intracellular membraneless organelle#GO:0043232;stereocilium#GO:0032420;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 LEPOC|Ensembl=ENSLOCG00000013049.1|UniProtKB=W5N617 W5N617 PTHR46091:SF2 BLR7054 PROTEIN AMINE OXIDASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000009335.1|UniProtKB=W5MSM7 W5MSM7 PTHR24081:SF12 NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B LOC100001692 PROTEIN transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;binding#GO:0005488;transcription regulator activity#GO:0140110;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000002042.1|UniProtKB=W5M1W1 W5M1W1 PGPEP1 PTHR23402:SF27 PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED PYROGLUTAMYL-PEPTIDASE I catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000008726.1|UniProtKB=W5MQF7 W5MQF7 PTHR28399:SF1 BARTTIN BARTTIN molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 monoatomic anion transport#GO:0006820;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000015237.1|UniProtKB=W5NDQ0 W5NDQ0 PTHR12587:SF16 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-BETA-1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;neuromuscular junction development#GO:0007528;cellular component organization#GO:0016043;synapse organization#GO:0050808;cellular process#GO:0009987 presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical structure#GO:0110165;presynaptic active zone#GO:0048786;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007883.1|UniProtKB=W5MMG5 W5MMG5 PTHR32465:SF0 BARDET-BIEDL SYNDROME 2 PROTEIN BBSOME COMPLEX MEMBER BBS2 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;neuron projection#GO:0043005;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;BBSome#GO:0034464;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000003552.1|UniProtKB=W5M744 W5M744 PTHR19855:SF16 WD40 REPEAT PROTEIN 12, 37 F-BOX_WD REPEAT-CONTAINING PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000009384.1|UniProtKB=W5MSW8 W5MSW8 PTHR45981:SF4 LD02310P E3 UBIQUITIN-PROTEIN LIGASE MARCHF8 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;binding#GO:0005488;signaling receptor binding#GO:0005102;MHC protein binding#GO:0042287;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;response to stimulus#GO:0050896;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;antigen processing and presentation#GO:0019882;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;immune system process#GO:0002376;protein modification by small protein conjugation or removal#GO:0070647 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;vacuole#GO:0005773;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;early endosome membrane#GO:0031901;late endosome membrane#GO:0031902 LEPOC|Ensembl=ENSLOCG00000016323.1|UniProtKB=W5NHP5 W5NHP5 PTHR47980:SF23 LD44762P SMALL MONOMERIC GTPASE localization within membrane#GO:0051668;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;secretion by cell#GO:0032940;endocytic recycling#GO:0032456;export from cell#GO:0140352;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;exocytosis#GO:0006887;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;endomembrane system#GO:0012505;secretory vesicle#GO:0099503;membrane#GO:0016020 TGF-beta signaling pathway#P00052>Ras-GTP#P01280;TGF-beta signaling pathway#P00052>Ras-GDP#P01291 LEPOC|Ensembl=ENSLOCG00000003357.1|UniProtKB=W5M6G1 W5M6G1 PTHR46943:SF2 PENTRAXIN-RELATED PROTEIN PTX3 NOVEL PROTEIN SIMILAR TO VERTEBRATE PENTAXIN-RELATED LEPOC|Ensembl=ENSLOCG00000016858.1|UniProtKB=W5NJN3 W5NJN3 PTHR11616:SF316 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SOLUTE CARRIER FAMILY 6 MEMBER 1 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;amino acid transport#GO:0006865;transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000017232.1|UniProtKB=W5NL05 W5NL05 PTHR28676:SF2 ALK AND LTK LIGAND 2-RELATED ALK AND LTK LIGAND 2 protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;molecular function regulator activity#GO:0098772;protein kinase activator activity#GO:0030295;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;kinase activator activity#GO:0019209 regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533 LEPOC|Ensembl=ENSLOCG00000007685.1|UniProtKB=W5MLS1 W5MLS1 PTHR11829:SF406 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN I1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000008429.1|UniProtKB=W5MPD7 W5MPD7 PTHR19424:SF0 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to heat#GO:0034605;response to heat#GO:0009408;heat acclimation#GO:0010286;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000005718.1|UniProtKB=W5MEU4 W5MEU4 PTHR22847:SF731 WD40 REPEAT PROTEIN TNF RECEPTOR-ASSOCIATED FACTOR 7 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000003675.1|UniProtKB=W5M7K4 W5M7K4 PTHR16465:SF0 NUCLEASE-RELATED ZINC FINGER MATRIN-TYPE PROTEIN 5 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000011899.1|UniProtKB=W5N1X4 W5N1X4 PTHR10639:SF28 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN B clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;synapse#GO:0045202;clathrin coat#GO:0030118;organelle#GO:0043226;clathrin vesicle coat#GO:0030125;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;cell junction#GO:0030054;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;vesicle coat#GO:0030120;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133 vesicle coat protein#PC00235;membrane traffic protein#PC00150 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Huntington disease#P00029>Clathrin#P00798;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 LEPOC|Ensembl=ENSLOCG00000000693.1|UniProtKB=W5LXB6 W5LXB6 PTHR11740:SF45 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 LEPOC|Ensembl=ENSLOCG00000005960.1|UniProtKB=W5MFN7 W5MFN7 PTHR12011:SF435 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G1-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016041.1|UniProtKB=W5NGK3 W5NGK3 PTHR11958:SF20 SODIUM/DICARBOXYLATE SYMPORTER-RELATED NEUTRAL AMINO ACID TRANSPORTER A monoatomic cation transmembrane transporter activity#GO:0008324;sodium:dicarboxylate symporter activity#GO:0017153;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175 L-glutamate import#GO:0051938;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;localization#GO:0051179;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;transport#GO:0006810;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000006646.1|UniProtKB=W5MI38 W5MI38 PTHR24133:SF33 ANKYRIN DOMAIN-CONTAINING ANKYRIN-3 ISOFORM X1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;transmembrane transporter binding#GO:0044325;molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092;cytoskeletal adaptor activity#GO:0008093 protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to plasma membrane#GO:0072659;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009568.1|UniProtKB=W5MTI6 W5MTI6 PTHR16165:SF9 NXPE FAMILY MEMBER NXPE FAMILY MEMBER 3 LEPOC|Ensembl=ENSLOCG00000006329.1|UniProtKB=W5MGX7 W5MGX7 PTHR13929:SF17 1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE UBIA PRENYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;menaquinone biosynthetic process#GO:0009234;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;vitamin K metabolic process#GO:0042373;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000001699.1|UniProtKB=W5M0R3 W5M0R3 PTHR11540:SF76 MALATE AND LACTATE DEHYDROGENASE MALATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000002009.1|UniProtKB=W5M1T1 W5M1T1 PTHR45662:SF2 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000181.1|UniProtKB=W5LVP5 W5LVP5 PTHR20914:SF50 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 PHOSPHOLIPASE A2 INHIBITOR AND LY6_PLAUR DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005289.1|UniProtKB=W5MDB4 W5MDB4 PTHR24304:SF6 CYTOCHROME P450 FAMILY 7 CHOLESTEROL 7-ALPHA-MONOOXYGENASE monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cholesterol homeostasis#GO:0042632;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;homeostatic process#GO:0042592;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015282.1|UniProtKB=W5NDU9 W5NDU9 PTHR10782:SF38 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713;SUMO transferase activity#GO:0019789;transcription regulator activity#GO:0140110;SUMO ligase activity#GO:0061665;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678 regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of transcription by RNA polymerase II#GO:0006357;metabolic process#GO:0008152;protein sumoylation#GO:0016925;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968 intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015111.1|UniProtKB=W5ND90 W5ND90 PTHR15073:SF5 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 3 biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cellular process#GO:0050794;regulation of microtubule-based movement#GO:0060632;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000008452.1|UniProtKB=W5MPH3 W5MPH3 PTHR44144:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016749.1|UniProtKB=W5NJ94 W5NJ94 PTHR45972:SF2 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH-LIKE PROTEIN 42 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of microtubule-based process#GO:0032886;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463 LEPOC|Ensembl=ENSLOCG00000015466.1|UniProtKB=W5NEI2 W5NEI2 PTHR11736:SF14 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016571.1|UniProtKB=W5NIL4 W5NIL4 PTHR11785:SF246 AMINO ACID TRANSPORTER CYSTINE_GLUTAMATE TRANSPORTER amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 transport#GO:0006810;cellular process#GO:0009987;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001805.1|UniProtKB=W5M128 W5M128 PTHR14537:SF0 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 11 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 11 LEPOC|Ensembl=ENSLOCG00000011624.1|UniProtKB=W5N0X5 W5N0X5 PTHR46941:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 126 COILED-COIL DOMAIN-CONTAINING PROTEIN 126 LEPOC|Ensembl=ENSLOCG00000004357.1|UniProtKB=W5M9Z5 W5M9Z5 PTHR12665:SF13 ORMDL PROTEINS ORM1-LIKE PROTEIN 2 ceramide metabolic process#GO:0006672;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;cellular process#GO:0009987 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000005169.1|UniProtKB=W5MCW4 W5MCW4 PTHR20914:SF50 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 PHOSPHOLIPASE A2 INHIBITOR AND LY6_PLAUR DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010532.1|UniProtKB=W5MWZ6 W5MWZ6 PTHR14208:SF0 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN EIF5-MIMIC PROTEIN 2 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000009284.1|UniProtKB=W5MSI1 W5MSI1 PTHR45725:SF16 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 1 actin cytoskeleton#GO:0015629;actomyosin#GO:0042641;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;stress fiber#GO:0001725;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005520.1|UniProtKB=W5ME58 W5ME58 PTHR23511:SF6 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2C biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of neurotransmitter secretion#GO:0046928;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;cytoplasm#GO:0005737;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000001347.1|UniProtKB=W5LZH4 W5LZH4 PTHR13154:SF5 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2B translation regulator activity#GO:0045182 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of translation#GO:0017148;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000004145.1|UniProtKB=W5M999 W5M999 PTHR23292:SF45 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR HOMOLOG-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;zinc ion binding#GO:0008270 intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;cytoplasmic side of membrane#GO:0098562;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;nucleus#GO:0005634;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002701.1|UniProtKB=W5M482 W5M482 PTHR13808:SF34 CBP/P300-RELATED CREB-BINDING PROTEIN chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;nucleic acid binding#GO:0003676;protein-lysine-acetyltransferase activity#GO:0061733;histone acetyltransferase activity#GO:0004402;DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transcription regulator activity#GO:0140110;binding#GO:0005488;acetyltransferase activity#GO:0016407;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;transcription coactivator activity#GO:0003713;protein N-acetyltransferase activity#GO:0034212 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226 histone modifying enzyme#PC00261 Wnt signaling pathway#P00057>CBP#P01448;Huntington disease#P00029>CBP#P00777;p53 pathway#P00059>CBP#P04623;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Transcription regulation by bZIP transcription factor#P00055>CBP/P300#P01387;Gonadotropin-releasing hormone receptor pathway#P06664>CBP#P06755;Hypoxia response via HIF activation#P00030>P300#P00814;Hedgehog signaling pathway#P00025>CBP#P00691 LEPOC|Ensembl=ENSLOCG00000015829.1|UniProtKB=W5NFS7 W5NFS7 PTHR10048:SF119 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 cell motility#GO:0048870;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phosphatidylinositol phosphate biosynthetic process#GO:0046854;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;glycerophospholipid metabolic process#GO:0006650;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000012460.1|UniProtKB=W5N3Y1 W5N3Y1 PTHR10218:SF85 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-13 protein binding#GO:0005515;hydrolase activity#GO:0016787;signaling receptor binding#GO:0005102;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556;G protein-coupled receptor signaling pathway#GO:0007186 apical part of cell#GO:0045177;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;brush border#GO:0005903;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;brush border membrane#GO:0031526;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;cell projection membrane#GO:0031253;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;cytoplasmic side of plasma membrane#GO:0009898;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 heterotrimeric G-protein#PC00117;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000012064.1|UniProtKB=W5N2I7 W5N2I7 PTHR23073:SF31 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 10B ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;response to endoplasmic reticulum stress#GO:0034976;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of DNA-templated transcription initiation#GO:2000142;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;macromolecule catabolic process#GO:0009057;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of cellular component biogenesis#GO:0044089;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;positive regulation of cellular component organization#GO:0051130;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087 proteasome complex#GO:0000502;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000007462.1|UniProtKB=W5MKZ8 W5MKZ8 PTHR13387:SF9 PROTEIN HGH1 HOMOLOG CO-CHAPERONE PROTEIN HGH1 HOMOLOG LEPOC|Ensembl=ENSLOCG00000006374.1|UniProtKB=W5MH33 W5MH33 PTHR12122:SF5 RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cell projection membrane#GO:0031253;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;plasma membrane region#GO:0098590 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000018088.1|UniProtKB=W5NNI0 W5NNI0 PTHR28564:SF1 STANNIN STANNIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000000389.1|UniProtKB=W5LWB7 W5LWB7 PTHR10121:SF0 COATOMER SUBUNIT DELTA COATOMER SUBUNIT DELTA protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;organelle localization#GO:0051640;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vesicle coat#GO:0030120;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;COPI-coated vesicle#GO:0030137;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150;vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000015884.1|UniProtKB=W5NG03 W5NG03 PTHR45618:SF8 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 response to stimulus#GO:0050896;response to cold#GO:0009409;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950 mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006636.1|UniProtKB=W5MI06 W5MI06 PTHR46788:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 5 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 5 reproductive process#GO:0022414;cell motility#GO:0048870;cellular process#GO:0009987;sperm motility#GO:0097722 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;organelle#GO:0043226 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000010878.1|UniProtKB=W5MY71 W5MY71 PTHR24359:SF19 SERINE/THREONINE-PROTEIN KINASE SBK1 SERINE_THREONINE-PROTEIN KINASE SBK1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008599.1|UniProtKB=W5MQ12 W5MQ12 PTHR24125:SF0 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1A LEPOC|Ensembl=ENSLOCG00000001553.1|UniProtKB=W5M083 W5M083 PTHR33966:SF1 PROTEIN ODR-4 HOMOLOG PROTEIN ODR-4 HOMOLOG macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179 LEPOC|Ensembl=ENSLOCG00000004918.1|UniProtKB=W5MC05 W5MC05 PTHR45709:SF6 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED LARGE SUBUNIT GTPASE 1 HOMOLOG hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;organelle localization#GO:0051640;ribosome biogenesis#GO:0042254;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001452.1|UniProtKB=W5LZU9 W5LZU9 PTHR15892:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000006716.1|UniProtKB=W5MIA2 W5MIA2 PTHR10395:SF14 URICASE AND TRANSTHYRETIN-RELATED TRANSTHYRETIN nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;primary metabolic process#GO:0044238 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008920.1|UniProtKB=W5MR68 W5MR68 PTHR11566:SF23 DYNAMIN DYNAMIN-2 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;ribonucleoside triphosphate phosphatase activity#GO:0017111;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;GTPase activity#GO:0003924;protein binding#GO:0005515;hydrolase activity#GO:0016787 synaptic vesicle transport#GO:0048489;receptor internalization#GO:0031623;organelle organization#GO:0006996;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;synaptic vesicle recycling#GO:0036465;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;membrane organization#GO:0061024;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;receptor-mediated endocytosis#GO:0006898;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488;establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;organelle localization#GO:0051640;cellular localization#GO:0051641;localization#GO:0051179 microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004819.1|UniProtKB=W5MBM5 W5MBM5 PTHR12167:SF2 C-TYPE NATRIURETIC PEPTIDE C-TYPE NATRIURETIC PEPTIDE molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;hormone receptor binding#GO:0051427 metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>CNP#G06905;Gonadotropin-releasing hormone receptor pathway#P06664>CNP#P06824;Gonadotropin-releasing hormone receptor pathway#P06664>CNP#G06690 LEPOC|Ensembl=ENSLOCG00000007541.1|UniProtKB=W5ML94 W5ML94 PTHR11871:SF6 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B DELTA ISOFORM protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 LEPOC|Ensembl=ENSLOCG00000010097.1|UniProtKB=W5MVE6 W5MVE6 PTHR24136:SF17 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 9 protein modification by small protein conjugation or removal#GO:0070647;positive regulation of protein metabolic process#GO:0051247;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;positive regulation of metabolic process#GO:0009893;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;metabolic process#GO:0008152;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567 LEPOC|Ensembl=ENSLOCG00000002299.1|UniProtKB=W5M2S9 W5M2S9 PTHR19305:SF42 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 29 binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 transport#GO:0006810;exocytosis#GO:0006887;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;cellular component organization#GO:0016043;export from cell#GO:0140352;vesicle fusion#GO:0006906 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150;SNARE protein#PC00034 5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049 LEPOC|Ensembl=ENSLOCG00000012264.1|UniProtKB=W5N394 W5N394 PTHR23113:SF174 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 1 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of lymphocyte mediated immunity#GO:0002706;immune system process#GO:0002376;regulation of cell killing#GO:0031341;T cell activation#GO:0042110;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of response to external stimulus#GO:0032103;B cell activation#GO:0042113;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;lymphocyte activation#GO:0046649;regulation of response to external stimulus#GO:0032101;intracellular signaling cassette#GO:0141124;Ras protein signal transduction#GO:0007265;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell activation#GO:0001775;cell communication#GO:0007154;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of immune effector process#GO:0002697;regulation of leukocyte mediated cytotoxicity#GO:0001910;intracellular signal transduction#GO:0035556;leukocyte activation#GO:0045321;regulation of leukocyte mediated immunity#GO:0002703;cellular response to stimulus#GO:0051716;regulation of natural killer cell mediated immunity#GO:0002715;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of response to biotic stimulus#GO:0002831;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;positive regulation of immune effector process#GO:0002699 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 LEPOC|Ensembl=ENSLOCG00000001959.1|UniProtKB=W5M1M5 W5M1M5 PTHR12369:SF46 CHONDROITIN SYNTHASE N-ACETYL-BETA-GLUCOSAMINYL-GLYCOPROTEIN 4-BETA-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000007566.1|UniProtKB=W5MLC5 W5MLC5 PTHR10644:SF1 DNA REPAIR/RNA PROCESSING CPSF FAMILY SPLICING FACTOR 3B SUBUNIT 3 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;U2 snRNP#GO:0005686;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;Sm-like protein family complex#GO:0120114 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005127.1|UniProtKB=W5MCR1 W5MCR1 PTHR11486:SF26 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 3 signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104 system development#GO:0048731;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of cellular process#GO:0048522;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207;growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000012246.1|UniProtKB=W5N357 W5N357 PTHR15225:SF1 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN INTERFERON-INDUCED 35 KDA PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011080.1|UniProtKB=W5MYZ2 W5MYZ2 PTHR31020:SF1 TRANSMEMBRANE PROTEIN 174 TRANSMEMBRANE PROTEIN 174 LEPOC|Ensembl=ENSLOCG00000015604.1|UniProtKB=W5NF03 W5NF03 PTHR11705:SF94 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A1 metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000012661.1|UniProtKB=W5N4M4 W5N4M4 PTHR12821:SF0 BYSTIN BYSTIN nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515;RNA binding#GO:0003723 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000010012.1|UniProtKB=W5MV30 W5MV30 PTHR24412:SF462 KELCH PROTEIN KELCH-LIKE PROTEIN 38 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007655.1|UniProtKB=W5MLN5 W5MLN5 PTHR12630:SF20 N-LINKED OLIGOSACCHARIDE PROCESSING GLUCOSIDASE 2 SUBUNIT BETA biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative biosynthetic process#GO:1901137;animal organ development#GO:0048513;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;developmental process#GO:0032502;metabolic process#GO:0008152;liver development#GO:0001889;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;animal gross anatomical part developmental process#GO:0160108 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013038.1|UniProtKB=W5N5Z9 W5N5Z9 PTHR47501:SF10 TRANSPOSASE-RELATED DUF659 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000006446.1|UniProtKB=W5MHD2 W5MHD2 PTHR20938:SF0 INTEGRATOR COMPLEX SUBUNIT 4 INTEGRATOR COMPLEX SUBUNIT 4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA 3'-end processing#GO:0034472;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;catabolic process#GO:0009056;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;integrator complex#GO:0032039;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000010058.1|UniProtKB=W5MV93 W5MV93 PTHR45776:SF6 MIP04163P MELANOCYTE-INDUCING TRANSCRIPTION FACTOR B RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000003163.1|UniProtKB=W5M5T0 W5M5T0 PTHR11599:SF244 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-1 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000002350.1|UniProtKB=W5M2Z6 W5M2Z6 PTHR13678:SF12 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37D intracellular protein transport#GO:0006886;protein targeting to membrane#GO:0006612;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;protein targeting to vacuole#GO:0006623;protein transport#GO:0015031;cellular localization#GO:0051641;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;localization#GO:0051179;protein metabolic process#GO:0019538;localization within membrane#GO:0051668;protein localization to vacuole#GO:0072665;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000014260.1|UniProtKB=W5NA96 W5NA96 PTHR28422:SF1 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 39 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 39 regulation of cell communication#GO:0010646;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008322.1|UniProtKB=W5MP01 W5MP01 PTHR16294:SF5 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN generation of neurons#GO:0048699;regulation of secretion by cell#GO:1903530;cellular component organization#GO:0016043;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of neurotransmitter secretion#GO:0046928;regulation of transport#GO:0051049;regulation of localization#GO:0032879;microtubule-based process#GO:0007017;vesicle organization#GO:0016050;establishment of vesicle localization#GO:0051650;axonal transport#GO:0098930;organelle localization#GO:0051640;system development#GO:0048731;anterograde axonal transport#GO:0008089;localization#GO:0051179;regulation of secretion#GO:0051046;developmental process#GO:0032502;anterograde synaptic vesicle transport#GO:0048490;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle localization#GO:0051648;axo-dendritic transport#GO:0008088;regulation of signal transduction#GO:0009966;plasma membrane bounded cell projection organization#GO:0120036;microtubule-based transport#GO:0099111;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular localization#GO:0051641;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of synaptic vesicle exocytosis#GO:2000300;cell development#GO:0048468;establishment of organelle localization#GO:0051656;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;synaptic vesicle transport#GO:0048489;endomembrane system organization#GO:0010256;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;regulation of trans-synaptic signaling#GO:0099177;synaptic vesicle localization#GO:0097479;regulation of exocytosis#GO:0017157;anatomical structure development#GO:0048856;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;regulation of response to stimulus#GO:0048583;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;vesicle cytoskeletal trafficking#GO:0099518;neurogenesis#GO:0022008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705 intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;BLOC-1 complex#GO:0031083;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular vesicle#GO:0097708;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000016243.1|UniProtKB=W5NHB9 W5NHB9 PTHR23087:SF2 NONHISTONE CHROMOSOMAL PROTEIN HMG HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 3 binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006340.1|UniProtKB=W5MGZ7 W5MGZ7 PTHR13011:SF0 TFIIF-ALPHA GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1 RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488;transcription factor binding#GO:0008134;RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIFalpha#P00663;Transcription regulation by bZIP transcription factor#P00055>TFIIFalpha#P01391 LEPOC|Ensembl=ENSLOCG00000015267.1|UniProtKB=W5NDS8 W5NDS8 PTHR47078:SF1 CYTOSKELETON-ASSOCIATED PROTEIN 2-LIKE CYTOSKELETON-ASSOCIATED PROTEIN 2-LIKE intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013760.1|UniProtKB=W5N8L2 W5N8L2 PTHR12210:SF173 DULLARD PROTEIN PHOSPHATASE CTD SMALL PHOSPHATASE-LIKE PROTEIN 2 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000017716.1|UniProtKB=W5NMG2 W5NMG2 PTHR16277:SF6 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 4 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000000457.1|UniProtKB=W5LWJ3 W5LWJ3 PTHR11309:SF90 FRIZZLED FRIZZLED-8 Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;non-canonical Wnt signaling pathway#GO:0035567 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Angiogenesis#P00005>Fzd#P00189 LEPOC|Ensembl=ENSLOCG00000013674.1|UniProtKB=W5N8A0 W5N8A0 PTHR15749:SF4 FANCONI-ASSOCIATED NUCLEASE 1 FANCONI-ASSOCIATED NUCLEASE 1 LEPOC|Ensembl=ENSLOCG00000003005.1|UniProtKB=W5M5E6 W5M5E6 PTHR18866:SF130 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE PROPIONYL-COA CARBOXYLASE ALPHA CHAIN, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 LEPOC|Ensembl=ENSLOCG00000014990.1|UniProtKB=W5NCV0 W5NCV0 PTHR21564:SF2 BRAKELESS PROTEIN ZINC FINGER PROTEIN 609 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000003668.1|UniProtKB=W5M7M8 W5M7M8 PTHR11339:SF373 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED IGGFC-BINDING PROTEIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000008987.1|UniProtKB=W5MRE1 W5MRE1 PTHR23049:SF8 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN LIGHT CHAIN 5 cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000005450.1|UniProtKB=W5MDW5 W5MDW5 PTHR22896:SF3 CDK5 AND ABL1 ENZYME SUBSTRATE 1 CDK5 AND ABL1 ENZYME SUBSTRATE 2 LEPOC|Ensembl=ENSLOCG00000012349.1|UniProtKB=W5N3K2 W5N3K2 PTHR14145:SF2 26S PROTESOME SUBUNIT 6 COP9 SIGNALOSOME COMPLEX SUBUNIT 1 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of protein stability#GO:0031647;cellular process#GO:0009987;biological regulation#GO:0065007;post-translational protein modification#GO:0043687 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000002977.1|UniProtKB=W5M569 W5M569 PTHR21091:SF169 METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED UROPORPHYRINOGEN DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779;cellular process#GO:0009987;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole biosynthetic process#GO:0033014 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 methyltransferase#PC00155 Heme biosynthesis#P02746>Uroporphyrinogen decarboxylase#P02975 LEPOC|Ensembl=ENSLOCG00000012683.1|UniProtKB=W5N4Q4 W5N4Q4 AFMID PTHR23024:SF574 ARYLACETAMIDE DEACETYLASE KYNURENINE FORMAMIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 deacetylase#PC00087 LEPOC|Ensembl=ENSLOCG00000005295.1|UniProtKB=W5MDE0 W5MDE0 PTHR12767:SF11 BCL7 RELATED B-CELL CLL_LYMPHOMA 7 PROTEIN FAMILY MEMBER A Notch signaling pathway#GO:0007219;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;ATPase complex#GO:1904949;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 LEPOC|Ensembl=ENSLOCG00000005595.1|UniProtKB=W5MEE6 W5MEE6 PTHR14742:SF0 RIBONUCLEASE P SUBUNIT P21 RIBONUCLEASE P PROTEIN SUBUNIT P21 tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;endonuclease complex#GO:1905348;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleolar ribonuclease P complex#GO:0005655;ribonuclease P complex#GO:0030677;endoribonuclease complex#GO:1902555;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000009512.1|UniProtKB=W5MTC3 W5MTC3 PTHR23043:SF30 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 3 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000000835.1|UniProtKB=W5LXS3 W5LXS3 PTHR10489:SF627 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 8 cytokine receptor activity#GO:0004896;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;molecular transducer activity#GO:0060089;protein binding#GO:0005515 calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cellular process#GO:0009987;immune response#GO:0006955;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;chemotaxis#GO:0006935;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;locomotion#GO:0040011;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000009189.1|UniProtKB=W5MS47 W5MS47 PTHR11143:SF7 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER RIBOSOMAL PROTEIN L26 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000014279.1|UniProtKB=W5NAB9 W5NAB9 PTHR12577:SF7 DACHSHUND DACHSHUND HOMOLOG 2 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000011919.1|UniProtKB=W5N1Z4 W5N1Z4 PTHR13379:SF0 UNCHARACTERIZED DUF1308 UPF0415 PROTEIN C7ORF25 LEPOC|Ensembl=ENSLOCG00000003433.1|UniProtKB=W5M6U0 W5M6U0 PTHR19384:SF63 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE 1 oxidoreductase activity, acting on NAD(P)H#GO:0016651;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;monooxygenase activity#GO:0004497;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 metabolic process#GO:0008152;response to lipopolysaccharide#GO:0032496;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;arginine metabolic process#GO:0006525;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;response to lipid#GO:0033993;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;regulation of biological quality#GO:0065008;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;system process#GO:0003008;carboxylic acid catabolic process#GO:0046395;regulation of blood pressure#GO:0008217;biosynthetic process#GO:0009058;biological regulation#GO:0065007;amino acid metabolic process#GO:0006520;response to other organism#GO:0051707;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;proteinogenic amino acid metabolic process#GO:0170039;response to bacterium#GO:0009617;circulatory system process#GO:0003013;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to external biotic stimulus#GO:0043207;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cytosol#GO:0005829;nucleus#GO:0005634;cell periphery#GO:0071944;cell junction#GO:0030054 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Gonadotropin-releasing hormone receptor pathway#P06664>NOSI#G06888;Gonadotropin-releasing hormone receptor pathway#P06664>NOSI#P06741;CCKR signaling map#P06959>NOS1#P07158 LEPOC|Ensembl=ENSLOCG00000004996.1|UniProtKB=W5MCB4 W5MCB4 PTHR12270:SF23 GLYCOSYLTRANSFERASE-RELATED XYLOSYL- AND GLUCURONYLTRANSFERASE LARGE2 glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;xylosyltransferase activity#GO:0042285;pentosyltransferase activity#GO:0016763;glucuronosyltransferase activity#GO:0015020 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000015117.1|UniProtKB=W5ND94 W5ND94 PTHR45695:SF6 LEUCOKININ RECEPTOR-RELATED BOMBESIN RECEPTOR SUBTYPE-3 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004567.1|UniProtKB=W5MAQ7 W5MAQ7 PTHR31848:SF2 REFILIN-A-RELATED REFILIN-B regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of developmental process#GO:0050793;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of bone mineralization#GO:0030500;regulation of multicellular organismal process#GO:0051239;skeletal system morphogenesis#GO:0048705;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595 LEPOC|Ensembl=ENSLOCG00000006318.1|UniProtKB=W5MGX3 W5MGX3 PTHR11533:SF42 PROTEASE M1 ZINC METALLOPROTEASE LEUCYL-CYSTINYL AMINOPEPTIDASE metallopeptidase activity#GO:0008237;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 circulatory system process#GO:0003013;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;catabolic process#GO:0009056;metabolic process#GO:0008152;system process#GO:0003008;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;peptide catabolic process#GO:0043171;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005416.1|UniProtKB=W5MDS5 W5MDS5 PTHR16040:SF10 AUSTRALIN, ISOFORM A-RELATED BOREALIN-2 organelle localization#GO:0051640;nuclear division#GO:0000280;organelle fission#GO:0048285;localization#GO:0051179;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic metaphase chromosome alignment#GO:0007080;mitotic cell cycle#GO:0000278;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;chromosome localization#GO:0050000 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;microtubule cytoskeleton#GO:0015630;chromosome#GO:0005694;chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000010523.1|UniProtKB=W5MX02 W5MX02 PTHR11636:SF84 POU DOMAIN PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009747.1|UniProtKB=W5MU72 W5MU72 PTHR11485:SF31 TRANSFERRIN SEROTRANSFERRIN response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external stimulus#GO:0009605;defense response#GO:0006952;establishment of localization#GO:0051234;antibacterial humoral response#GO:0019731;transport#GO:0006810;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;metal ion transport#GO:0030001;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;defense response to bacterium#GO:0042742;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;response to bacterium#GO:0009617;immune system process#GO:0002376 recycling endosome#GO:0055037;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;extracellular region#GO:0005576;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000013987.1|UniProtKB=W5N9D4 W5N9D4 PTHR20855:SF38 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR GAMMA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006249.1|UniProtKB=W5MGN6 W5MGN6 PTHR11849:SF16 ETS TRANSCRIPTION FACTOR PU.1 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 Interleukin signaling pathway#P00036>Ets#P00989 LEPOC|Ensembl=ENSLOCG00000014450.1|UniProtKB=W5NAX5 W5NAX5 PTHR21622:SF0 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;mitochondrial transport#GO:0006839;cellular localization#GO:0051641;protein metabolic process#GO:0019538;localization#GO:0051179;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;protein maturation#GO:0051604;mitochondrial protein import pathway#GO:7770058;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011595.1|UniProtKB=W5N0T8 W5N0T8 TEF PTHR11988:SF7 THYROTROPH EMBRYONIC FACTOR RELATED D SITE-BINDING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000016656.1|UniProtKB=W5NIW8 W5NIW8 PTHR11675:SF50 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 8-RELATED polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016584.1|UniProtKB=W5NIM7 W5NIM7 PTHR45715:SF23 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED ATPASE H+ TRANSPORTING V1 SUBUNIT E1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 ATPase complex#GO:1904949;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;proton-transporting two-sector ATPase complex#GO:0016469;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000018098.1|UniProtKB=W5NNJ0 W5NNJ0 PTHR11467:SF182 HISTONE H1 HISTONE H1.0 chromatin DNA binding#GO:0031490;DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682 biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;negative regulation of DNA recombination#GO:0045910;cellular component organization#GO:0016043;chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016222.1|UniProtKB=W5NH92 W5NH92 PTHR11003:SF59 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215 monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000015370.1|UniProtKB=W5NE56 W5NE56 PTHR11505:SF204 L1 TRANSPOSABLE ELEMENT-RELATED L1 TRANSPOSABLE ELEMENT RRM DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000015681.1|UniProtKB=W5NF95 W5NF95 PTHR11693:SF45 ATP SYNTHASE GAMMA CHAIN ATP SYNTHASE F(1) COMPLEX SUBUNIT GAMMA, MITOCHONDRIAL proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside phosphate biosynthetic process#GO:1901293 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ATP synthase#PC00002 ATP synthesis#P02721>F1 gamma#P02796 LEPOC|Ensembl=ENSLOCG00000007029.1|UniProtKB=W5MJF5 W5MJF5 PTHR24073:SF910 DRAB5-RELATED RAS-RELATED PROTEIN RAB-22A ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000002865.1|UniProtKB=W5M4R6 W5M4R6 PTHR10742:SF342 FLAVIN MONOAMINE OXIDASE L-AMINO-ACID OXIDASE ISOFORM X1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 oxidase#PC00175 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 LEPOC|Ensembl=ENSLOCG00000005302.1|UniProtKB=W5MDD4 W5MDD4 PTHR15561:SF0 CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000792.1|UniProtKB=W5LXP9 W5LXP9 PTHR21223:SF3 CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 2 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000016865.1|UniProtKB=W5NJN9 W5NJN9 PTHR12049:SF7 PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004585.1|UniProtKB=W5MAU7 W5MAU7 PTHR12015:SF108 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 20 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 LEPOC|Ensembl=ENSLOCG00000017023.1|UniProtKB=W5NK84 W5NK84 PTHR23339:SF127 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE 4A2B-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000008763.1|UniProtKB=W5MQK9 W5MQK9 PTHR24205:SF3 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of calcineurin-NFAT signaling cascade#GO:0070884;negative regulation of signal transduction#GO:0009968;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000004636.1|UniProtKB=W5MAZ9 W5MAZ9 PTHR24409:SF363 ZINC FINGER PROTEIN 142 ZINC FINGER AND BTB DOMAIN CONTAINING 32 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000017590.1|UniProtKB=W5NM36 W5NM36 PTHR10361:SF3 SODIUM-BILE ACID COTRANSPORTER P3 PROTEIN bile acid transmembrane transporter activity#GO:0015125;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;bile acid and bile salt transport#GO:0015721;establishment of localization#GO:0051234;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000006710.1|UniProtKB=W5MI98 W5MI98 PTHR24253:SF188 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 13A-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 sensory perception of sound#GO:0007605;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877;proteolysis#GO:0006508;biosynthetic process#GO:0009058;multicellular organismal process#GO:0032501;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;system process#GO:0003008;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000008156.1|UniProtKB=W5MNE1 W5MNE1 PTHR26451:SF980 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN GENE 7582-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008503.1|UniProtKB=W5MPP3 W5MPP3 PTHR11097:SF9 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP43 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nuclear mRNA surveillance#GO:0071028;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;rRNA processing#GO:0006364;snRNA metabolic process#GO:0016073;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;snRNA 3'-end processing#GO:0034472;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;maturation of 5.8S rRNA#GO:0000460;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000004691.1|UniProtKB=W5MB63 W5MB63 PTHR22443:SF16 NON-SPECIFIC LETHAL 1, ISOFORM M KAT8 REGULATORY NSL COMPLEX SUBUNIT 1-LIKE PROTEIN binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515 histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;chromatin#GO:0000785;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;NSL complex#GO:0044545;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000011717.1|UniProtKB=W5N199 W5N199 PTHR24240:SF77 OPSIN VISUAL PIGMENT-LIKE RECEPTOR PEROPSIN transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;detection of stimulus#GO:0051606;biological regulation#GO:0065007;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012820.1|UniProtKB=W5N561 W5N561 PTHR46074:SF6 CYSTEINE-RICH PROTEIN CRIP FAMILY MEMBER CYSTEINE-RICH PROTEIN 1 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006992.1|UniProtKB=W5MJA1 W5MJA1 PTHR11246:SF5 PRE-MRNA SPLICING FACTOR PRE-MRNA-SPLICING FACTOR SYF1 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397 catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000012454.1|UniProtKB=W5N3X2 W5N3X2 PTHR32205:SF5 ARCHAEMETZINCIN-2-RELATED ARCHAEMETZINCIN-2 LEPOC|Ensembl=ENSLOCG00000015625.1|UniProtKB=W5NF26 W5NF26 PTHR12429:SF36 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL3 ISOFORM X1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;protein localization to organelle#GO:0033365;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;protein transport#GO:0015031;localization#GO:0051179;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;transport#GO:0006810;intracellular protein localization#GO:0008104;import into cell#GO:0098657;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007241.1|UniProtKB=W5MK57 W5MK57 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009073.1|UniProtKB=W5MRP9 W5MRP9 PTHR13367:SF8 UBIQUITIN THIOESTERASE OTU DOMAIN-CONTAINING PROTEIN 7B hydrolase activity#GO:0016787;protein binding#GO:0005515;binding#GO:0005488;modification-dependent protein binding#GO:0140030;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;catalytic activity#GO:0003824;polyubiquitin modification-dependent protein binding#GO:0031593;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of intracellular signal transduction#GO:1902531;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of canonical NF-kappaB signal transduction#GO:0043122 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000012017.1|UniProtKB=W5N2B7 W5N2B7 PTHR15428:SF0 ENDOTHELIAL CELL-SPECIFIC MOLECULE 1 ESM-1 ENDOTHELIAL CELL-SPECIFIC MOLECULE 1 protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102 multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;tube development#GO:0035295;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;positive regulation of signaling#GO:0023056;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;circulatory system development#GO:0072359;regulation of cell communication#GO:0010646;blood vessel morphogenesis#GO:0048514;positive regulation of signal transduction#GO:0009967;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 LEPOC|Ensembl=ENSLOCG00000001952.1|UniProtKB=W5M1K8 W5M1K8 PTHR22972:SF7 SERINE/THREONINE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PINK1, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 positive regulation of cellular component organization#GO:0051130;process utilizing autophagic mechanism#GO:0061919;positive regulation of organelle organization#GO:0010638;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of programmed cell death#GO:0043067;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;regulation of developmental process#GO:0050793;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of developmental process#GO:0051094;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of cellular process#GO:0048522;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000004005.1|UniProtKB=W5M8R8 W5M8R8 PTHR12487:SF6 TEASHIRT-RELATED TEASHIRT HOMOLOG 1 DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000017713.1|UniProtKB=W5NMF9 W5NMF9 PTHR24399:SF21 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 1 sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000000968.1|UniProtKB=W5LY99 W5LY99 PTHR43272:SF101 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ACSBG2 ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000003002.1|UniProtKB=W5M579 W5M579 PTHR21245:SF2 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 18-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007316.1|UniProtKB=W5MKF1 W5MKF1 PTHR10845:SF34 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 1 enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000005637.1|UniProtKB=W5MEJ7 W5MEJ7 PTHR30616:SF5 UNCHARACTERIZED PROTEIN YFIH PURINE NUCLEOSIDE PHOSPHORYLASE LACC1 glycosyltransferase activity#GO:0016757;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824;transferase activity#GO:0016740;hydrolase activity#GO:0016787;adenosine deaminase activity#GO:0004000;pentosyltransferase activity#GO:0016763 immune system process#GO:0002376;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of response to biotic stimulus#GO:0002831;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;pattern recognition receptor signaling pathway#GO:0002221;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;activation of innate immune response#GO:0002218;regulation of metabolic process#GO:0019222;positive regulation of innate immune response#GO:0045089 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000014110.1|UniProtKB=W5N9S4 W5N9S4 PTHR48102:SF7 ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED ATP-DEPENDENT CLPX-LIKE CHAPERONE, MITOCHONDRIAL ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008415.1|UniProtKB=W5MPD5 W5MPD5 PTHR24025:SF20 DESMOGLEIN FAMILY MEMBER DACHSOUS CADHERIN RELATED 2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000002708.1|UniProtKB=W5M493 W5M493 PTHR12558:SF9 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 16 HOMOLOG enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of nuclear division#GO:0051783;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic nuclear division#GO:0007088;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;cell division#GO:0051301;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of chromosome separation#GO:1905818;positive regulation of cell cycle#GO:0045787;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome segregation#GO:0051983;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;protein modification by small protein conjugation#GO:0032446;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145 nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;cytoplasm#GO:0005737;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012650.1|UniProtKB=W5N4L7 W5N4L7 PTHR46049:SF2 AGAP003327-PA UNCONVENTIONAL MYOSIN-X phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;protein binding#GO:0005515;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;binding#GO:0005488;isomerase activity#GO:0016853;macromolecular conformation isomerase activity#GO:0120543;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;actin filament binding#GO:0051015;anion binding#GO:0043168;polypeptide conformation or assembly isomerase activity#GO:0120544;small molecule binding#GO:0036094;ion binding#GO:0043167 regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793;cellular localization#GO:0051641;localization#GO:0051179;regulation of cell projection assembly#GO:0060491;regulation of biological quality#GO:0065008;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;intracellular transport#GO:0046907;regulation of cell projection organization#GO:0031344;transport#GO:0006810;regulation of anatomical structure morphogenesis#GO:0022603;establishment of localization#GO:0051234;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of filopodium assembly#GO:0051489 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;filopodium#GO:0030175;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000001534.1|UniProtKB=W5M054 W5M054 PTHR10504:SF151 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED BACTERICIDAL PERMEABILITY-INCREASING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007810.1|UniProtKB=W5MM74 W5MM74 PTHR45695:SF7 LEUCOKININ RECEPTOR-RELATED GASTRIN-RELEASING PEPTIDE RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016482.1|UniProtKB=W5NIA3 W5NIA3 PTHR22948:SF15 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 6 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000833.1|UniProtKB=W5LXS6 W5LXS6 PTHR19848:SF10 WD40 REPEAT PROTEIN NOTCHLESS PROTEIN HOMOLOG 1 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002396.1|UniProtKB=W5M349 W5M349 PTHR24061:SF519 CALCIUM-SENSING RECEPTOR-RELATED VOMERONASAL TYPE-2 RECEPTOR 1 ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001083.1|UniProtKB=W5LYN8 W5LYN8 PTHR11835:SF84 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;carboxylic acid metabolic process#GO:0019752;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;generation of precursor metabolites and energy#GO:0006091 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000006670.1|UniProtKB=W5MI45 W5MI45 PTHR22923:SF67 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 4 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013283.1|UniProtKB=W5N6W4 W5N6W4 PTHR45760:SF1 FI19922P1-RELATED MITOCHONDRIAL GLUTATHIONE TRANSPORTER SLC25A39 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006183.1|UniProtKB=W5MGG3 W5MGG3 PTHR10201:SF21 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-17 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141 LEPOC|Ensembl=ENSLOCG00000014041.1|UniProtKB=W5N9J9 W5N9J9 PTHR46059:SF2 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 1 glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000006888.1|UniProtKB=W5MIX0 W5MIX0 PTHR47980:SF2 LD44762P RAS-RELATED PROTEIN RAB-40C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;export from cell#GO:0140352;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;localization#GO:0051179;protein metabolic process#GO:0019538;secretion#GO:0046903;secretion by cell#GO:0032940;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;exocytosis#GO:0006887;ubiquitin-dependent protein catabolic process#GO:0006511 cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000003911.1|UniProtKB=W5M8G5 W5M8G5 PTHR23253:SF9 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2 RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000009653.1|UniProtKB=W5MTT7 W5MTT7 PTHR19871:SF39 BETA TRANSDUCIN-RELATED PROTEIN NACHT AND WD REPEAT DOMAIN-CONTAINING PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000016348.1|UniProtKB=W5NHT2 W5NHT2 PTHR11730:SF32 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;homeostatic process#GO:0042592;cellular process#GO:0009987;nitrogen compound transport#GO:0071705 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000003255.1|UniProtKB=W5M634 W5M634 PTHR18444:SF9 UPF0538 FAMILY MEMBER UPF0538 PROTEIN C2ORF76 LEPOC|Ensembl=ENSLOCG00000016418.1|UniProtKB=W5NI20 W5NI20 PTHR23158:SF54 MELANOMA INHIBITORY ACTIVITY-RELATED TRANSPORT AND GOLGI ORGANIZATION PROTEIN 1 HOMOLOG vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;export from cell#GO:0140352;protein localization to extracellular region#GO:0071692;protein transport#GO:0015031;secretion by cell#GO:0032940;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;secretion#GO:0046903;protein secretion#GO:0009306;localization#GO:0051179 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015503.1|UniProtKB=W5NEM0 W5NEM0 PANX PTHR15759:SF7 PANNEXIN PANNEXIN-2 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000010335.1|UniProtKB=W5MWB1 W5MWB1 PTHR11254:SF299 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE E3 UBIQUITIN-PROTEIN LIGASE WWP1 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000012649.1|UniProtKB=W5N4L1 W5N4L1 PTHR16046:SF9 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR 2 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000007864.1|UniProtKB=W5MMD6 W5MMD6 PTHR10358:SF21 ENDOSULFINE ALPHA-ENDOSULFINE protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000012070.1|UniProtKB=W5N2J0 W5N2J0 PTHR10740:SF3 TRANSFORMING GROWTH FACTOR ALPHA PROBETACELLULIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of organelle organization#GO:0010638;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;positive regulation of cellular component organization#GO:0051130;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of nuclear division#GO:0051783;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;regulation of mitotic nuclear division#GO:0007088;cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 LEPOC|Ensembl=ENSLOCG00000017836.1|UniProtKB=W5NMT0 W5NMT0 PTHR10489:SF689 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;signaling#GO:0023052;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;neutrophil migration#GO:1990266;taxis#GO:0042330;response to chemical#GO:0042221;granulocyte migration#GO:0097530;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;neutrophil chemotaxis#GO:0030593;regulation of cellular process#GO:0050794;cell motility#GO:0048870;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cell chemotaxis#GO:0060326;intracellular signal transduction#GO:0035556;chemotaxis#GO:0006935;cell migration#GO:0016477;biological regulation#GO:0065007;immune response#GO:0006955;response to external stimulus#GO:0009605;myeloid leukocyte migration#GO:0097529;leukocyte chemotaxis#GO:0030595;calcium-mediated signaling#GO:0019722;leukocyte migration#GO:0050900 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 cell adhesion molecule#PC00069 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 LEPOC|Ensembl=ENSLOCG00000004276.1|UniProtKB=W5M9Q6 W5M9Q6 PTHR10334:SF64 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN LCCL DOMAIN-CONTAINING 2 carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 animal gross anatomical part developmental process#GO:0160108;anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856;head development#GO:0060322 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000009661.1|UniProtKB=W5MTU7 W5MTU7 PTHR21213:SF0 GEO09665P1-RELATED ZINC FINGER PROTEIN 706 LEPOC|Ensembl=ENSLOCG00000003657.1|UniProtKB=W5M7K0 W5M7K0 PTHR43939:SF130 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 4 cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;sexual reproduction#GO:0019953;nuclear division#GO:0000280;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;mitotic cell cycle process#GO:1903047;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensin complex#GO:0000796;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000006479.1|UniProtKB=W5MHH1 W5MHH1 PTHR10631:SF14 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000018133.1|UniProtKB=W5NNM5 W5NNM5 PTHR19256:SF65 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015344.1|UniProtKB=W5NE25 W5NE25 PTHR11825:SF70 SUBGROUP IIII AMINOTRANSFERASE BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE, CYTOSOLIC transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220 Isoleucine biosynthesis#P02748>Branched chain amino acid aminotransferase#P02994;Valine biosynthesis#P02785>Branched chain amino acid aminotransferase#P03215;Alanine biosynthesis#P02724>Branched chain amino acid aminotransferase#P02815;Leucine biosynthesis#P02749>Branched chain amino acid aminotransferase#P03000 LEPOC|Ensembl=ENSLOCG00000013655.1|UniProtKB=W5N877 W5N877 PTHR10285:SF171 URIDINE KINASE URACIL PHOSPHORIBOSYLTRANSFERASE HOMOLOG intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uracil phosphoribosyl transferase#P03151 LEPOC|Ensembl=ENSLOCG00000017695.1|UniProtKB=W5NME1 W5NME1 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000006915.1|UniProtKB=W5MJ31 W5MJ31 PTHR11347:SF139 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000016296.1|UniProtKB=W5NHK0 W5NHK0 PTHR23209:SF4 A-KINASE ANCHOR PROTEIN 12 A-KINASE ANCHOR PROTEIN 12 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015564.1|UniProtKB=W5NEV2 W5NEV2 PTHR24027:SF431 CADHERIN-23 CADHERIN-RELATED FAMILY MEMBER 5 ISOFORM X1 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell migration#GO:0016477;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330 anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796 cadherin#PC00057;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000006360.1|UniProtKB=W5MH39 W5MH39 PTHR24028:SF11 CADHERIN-87A PROTOCADHERIN-15 system process#GO:0003008;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;cell adhesion#GO:0007155;nervous system process#GO:0050877;visual perception#GO:0007601;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501;sensory perception of light stimulus#GO:0050953;cellular process#GO:0009987 plasma membrane#GO:0005886;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;cell junction#GO:0030054;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;synapse#GO:0045202;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000014122.1|UniProtKB=W5N9U1 W5N9U1 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 structural molecule activity#GO:0005198;protein binding#GO:0005515;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;binding#GO:0005488 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;single fertilization#GO:0007338;oogenesis#GO:0048477;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;developmental process#GO:0032502;sperm-egg recognition#GO:0035036;cell-cell recognition#GO:0009988;cellular developmental process#GO:0048869;germ cell development#GO:0007281;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;fertilization#GO:0009566;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell recognition#GO:0008037;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;binding of sperm to zona pellucida#GO:0007339 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 LEPOC|Ensembl=ENSLOCG00000016380.1|UniProtKB=W5NHX1 W5NHX1 PTHR24093:SF245 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 1 P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657 cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;regulation of cytosolic calcium ion concentration#GO:0051480;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000009868.1|UniProtKB=W5MUK0 W5MUK0 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED LEPOC|Ensembl=ENSLOCG00000012256.1|UniProtKB=W5N374 W5N374 PTHR44305:SF24 SI:DKEY-192D15.2-RELATED TYROSINE-PROTEIN KINASE C03B1.5-RELATED LEPOC|Ensembl=ENSLOCG00000017379.1|UniProtKB=W5NLH5 W5NLH5 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001090.1|UniProtKB=W5LYM3 W5LYM3 PTHR11604:SF2 PROFILIN PROFILIN-4 actin monomer binding#GO:0003785;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000004867.1|UniProtKB=W5MBU2 W5MBU2 PTHR12714:SF9 PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;O-methyltransferase activity#GO:0008171 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003600.1|UniProtKB=W5M7B5 W5M7B5 PTHR15832:SF1 SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG HETEROCHROMATIN PROTEIN 1-BINDING PROTEIN 3 chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015227.1|UniProtKB=W5NDP9 W5NDP9 PTHR24123:SF71 ANKYRIN REPEAT-CONTAINING ANKYRIN-1A ISOFORM X1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012819.1|UniProtKB=W5N571 W5N571 PTHR13055:SF10 TUMOR ENDOTHELIAL MARKER 7 RELATED PLEXIN DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000005463.1|UniProtKB=W5MDY8 W5MDY8 PTHR23239:SF349 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 18 cellular process#GO:0009987;organelle organization#GO:0006996;intermediate filament-based process#GO:0045103;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;intermediate filament cytoskeleton organization#GO:0045104 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000011825.1|UniProtKB=W5N1N7 W5N1N7 PTHR23113:SF150 GUANINE NUCLEOTIDE EXCHANGE FACTOR SON OF SEVENLESS HOMOLOG 2 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 T cell activation#P00053>SOS#P01307;FGF signaling pathway#P00021>SOS#P00641;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883;PI3 kinase pathway#P00048>SOS#P01185;Interleukin signaling pathway#P00036>SOS#P00981;Ras Pathway#P04393>SOS#P04552;Gonadotropin-releasing hormone receptor pathway#P06664>Sos#P06849;EGF receptor signaling pathway#P00018>SOS#P00558;PDGF signaling pathway#P00047>SOS#P01159;Angiogenesis#P00005>SOS-1#P00193;B cell activation#P00010>SOS#P00379;Integrin signalling pathway#P00034>SOS#P00920 LEPOC|Ensembl=ENSLOCG00000001511.1|UniProtKB=W5M016 W5M016 PTHR45632:SF15 LD33804P BTB DOMAIN-CONTAINING PROTEIN ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015589.1|UniProtKB=W5NEY4 W5NEY4 PTHR24215:SF31 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE-RICH PROTEIN 1 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010214.1|UniProtKB=W5MVU7 W5MVU7 PTHR21228:SF4 FAST LEU-RICH DOMAIN-CONTAINING FAS-ACTIVATED SERINE_THREONINE KINASE RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA stability#GO:0043487;mitochondrial gene expression#GO:0140053;regulation of RNA metabolic process#GO:0051252;mitochondrial RNA metabolic process#GO:0000959;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid biosynthetic process#GO:0141187;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;RNA processing#GO:0006396;gene expression#GO:0010467 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000014193.1|UniProtKB=W5NA27 W5NA27 PTHR15321:SF3 TUMOR SUPPRESSOR P53-BINDING PROTEIN 1 TP53-BINDING PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;DNA integrity checkpoint signaling#GO:0031570;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;DNA damage checkpoint signaling#GO:0000077;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;regulation of biosynthetic process#GO:0009889;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;negative regulation of cell cycle#GO:0045786 site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000000914.1|UniProtKB=W5LY35 W5LY35 PTHR15750:SF4 VASOHIBIN-1-LIKE ISOFORM X2 TUBULINYL-TYR CARBOXYPEPTIDASE 2 regulation of vasculature development#GO:1901342;regulation of angiogenesis#GO:0045765;regulation of anatomical structure morphogenesis#GO:0022603;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000008724.1|UniProtKB=W5MQF9 W5MQF9 PTHR11890:SF50 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-18 RECEPTOR 1 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013063.1|UniProtKB=W5N633 W5N633 PTHR10540:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 6 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000012531.1|UniProtKB=W5N486 W5N486 PTHR11731:SF20 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED A-TYPE POTASSIUM CHANNEL MODULATORY PROTEIN DPP6 peptidase activity#GO:0008233;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459 protein metabolic process#GO:0019538;proteolysis#GO:0006508;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062;metabolic process#GO:0008152;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000000923.1|UniProtKB=W5LY21 W5LY21 PTHR12772:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 intracellular membrane-bounded organelle#GO:0043231;GINS complex#GO:0000811;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008580.1|UniProtKB=W5MPY3 W5MPY3 PTHR15172:SF1 GALACTOCEREBROSIDASE GALACTOCEREBROSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative catabolic process#GO:1901136;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;ceramide metabolic process#GO:0006672;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosome#GO:0005764 galactosidase#PC00104;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002403.1|UniProtKB=W5M358 W5M358 PTHR11009:SF5 DER1-LIKE PROTEIN, DERLIN DERLIN-2 response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005525.1|UniProtKB=W5ME59 W5ME59 PTHR11818:SF21 BETA/GAMMA CRYSTALLIN CRYSTALLIN, BETA B1, LIKE 3 structural molecule activity#GO:0005198 sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000003480.1|UniProtKB=W5M6W6 W5M6W6 PTHR12264:SF21 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607 transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 LEPOC|Ensembl=ENSLOCG00000004296.1|UniProtKB=W5M9S0 W5M9S0 PTHR43466:SF1 2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED 2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000001893.1|UniProtKB=A0A075B5H8 A0A075B5H8 PTHR46385:SF1 PAIRED MESODERM HOMEOBOX PROTEIN 1-RELATED PAIRED MESODERM HOMEOBOX PROTEIN 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000005152.1|UniProtKB=W5MCU6 W5MCU6 PTHR19307:SF13 TUMOR PROTEIN D52 TUMOR PROTEIN D54 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012072.1|UniProtKB=W5N2J1 W5N2J1 PTHR15735:SF4 FCH AND DOUBLE SH3 DOMAINS PROTEIN F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 1 phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289 trans-synaptic signaling#GO:0099537;regulation of actin filament length#GO:0030832;cell communication#GO:0007154;regulation of biological quality#GO:0065008;chemical synaptic transmission#GO:0007268;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;regulation of actin filament-based process#GO:0032970;neuromuscular synaptic transmission#GO:0007274;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;synaptic signaling#GO:0099536;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of actin cytoskeleton organization#GO:0032956;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cell junction#GO:0030054;neuromuscular junction#GO:0031594;recycling endosome#GO:0055037;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000002341.1|UniProtKB=W5M2Z1 W5M2Z1 PTHR12756:SF24 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 1 binding#GO:0005488;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;protein binding#GO:0005515;metallocarboxypeptidase activity#GO:0004181;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;tubulin binding#GO:0015631;metalloexopeptidase activity#GO:0008235;cytoskeletal protein binding#GO:0008092;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000013890.1|UniProtKB=W5N924 W5N924 PTHR24093:SF377 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 2 monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626 intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;postsynaptic density membrane#GO:0098839;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;intracellular membrane-bounded organelle#GO:0043231;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000006238.1|UniProtKB=W5MGM2 W5MGM2 PTHR24071:SF0 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 protein transport#GO:0015031;protein import into nucleus#GO:0006606;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;ribosomal large subunit export from nucleus#GO:0000055;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;protein export from nucleus#GO:0006611;gene expression#GO:0010467;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular component biogenesis#GO:0044085;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;organelle localization#GO:0051640;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;nucleobase-containing compound transport#GO:0015931;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;transport#GO:0006810;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;RNA export from nucleus#GO:0006405;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036 nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000015085.1|UniProtKB=W5ND55 W5ND55 PTHR12406:SF47 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED TRIACYLGLYCEROL LIPASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;triacylglycerol lipase activity#GO:0004806;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 glycerolipid catabolic process#GO:0046503;triglyceride catabolic process#GO:0019433;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;homeostatic process#GO:0042592;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;triglyceride metabolic process#GO:0006641;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;neutral lipid metabolic process#GO:0006638;acylglycerol catabolic process#GO:0046464;cellular process#GO:0009987;lipid catabolic process#GO:0016042 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000009645.1|UniProtKB=W5MTT1 W5MTT1 PTHR15923:SF3 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING RECEPTOR 1 cargo receptor activity#GO:0038024 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000018274.1|UniProtKB=W5NP16 W5NP16 PTHR11984:SF65 CONNEXIN GAP JUNCTION BETA-3 PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cell junction#GO:0030054;anchoring junction#GO:0070161 gap junction#PC00105;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000012217.1|UniProtKB=W5N316 W5N316 PTHR19321:SF6 PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED PROTEIN REGULATOR OF CYTOKINESIS 1 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 chromosome segregation#GO:0007059;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;cellular process#GO:0009987;cellular component assembly#GO:0022607;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;nuclear division#GO:0000280;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278 intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;cytoplasm#GO:0005737;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012653.1|UniProtKB=W5N4L3 W5N4L3 PTHR24412:SF420 KELCH PROTEIN KELCH-LIKE PROTEIN 11 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002469.1|UniProtKB=W5M3J4 W5M3J4 PTHR19229:SF49 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA7 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;signaling receptor activity#GO:0038023;cargo receptor activity#GO:0038024;transmembrane signaling receptor activity#GO:0004888;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;phosphatidylcholine intramembrane carrier activity#GO:0008525;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303;molecular transducer activity#GO:0060089 cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cholesterol efflux#GO:0033344;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;phospholipid transport#GO:0015914;lipid localization#GO:0010876;transport#GO:0006810;sterol transport#GO:0015918;establishment of localization#GO:0051234;localization#GO:0051179;organic hydroxy compound transport#GO:0015850 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000010139.1|UniProtKB=W5MVK2 W5MVK2 PTHR31770:SF7 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER TAFA CHEMOKINE LIKE FAMILY MEMBER 4 signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chemokine#PC00074;cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000011338.1|UniProtKB=W5MZW9 W5MZW9 PTHR11220:SF7 HEME-BINDING PROTEIN-RELATED SOUL PROTEIN binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 LEPOC|Ensembl=ENSLOCG00000005252.1|UniProtKB=W5MD67 W5MD67 PTHR24103:SF667 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM69 ISOFORM X1 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001041.1|UniProtKB=W5LYG2 W5LYG2 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune system process#GO:0002376;immune effector process#GO:0002252;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune response#GO:0006955;response to stimulus#GO:0050896;adaptive immune response#GO:0002250 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010837.1|UniProtKB=W5MY24 W5MY24 PTHR24248:SF139 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(1A) DOPAMINE RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960 biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;G protein-coupled dopamine receptor signaling pathway#GO:0007212;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;adrenergic receptor signaling pathway#GO:0071875;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000010742.1|UniProtKB=W5MXQ8 W5MXQ8 PTHR25465:SF12 B-BOX DOMAIN CONTAINING TRIPARTITE MOTIF CONTAINING 65 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007918.1|UniProtKB=W5MMK8 W5MMK8 PTHR23290:SF0 RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5 RRNA N(6)-ADENOSINE-METHYLTRANSFERASE METTL5 N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649 metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 LEPOC|Ensembl=ENSLOCG00000005147.1|UniProtKB=W5MCT7 W5MCT7 PTHR23411:SF49 TAPASIN NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3 LIGAND 1 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009993.1|UniProtKB=W5MV31 W5MV31 PTHR10194:SF53 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 3 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000017992.1|UniProtKB=W5NN84 W5NN84 PTHR15035:SF11 CORTICOLIBERIN/UROCORTIN UROCORTIN molecular function inhibitor activity#GO:0140678;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;enzyme inhibitor activity#GO:0004857;signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018 G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;positive regulation of hormone secretion#GO:0046887;positive regulation of secretion#GO:0051047;positive regulation of signaling#GO:0023056;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of hormone secretion#GO:0046883;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of system process#GO:0044057;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;cell body#GO:0044297 intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000005239.1|UniProtKB=W5MD49 W5MD49 PTHR10829:SF15 CORTACTIN AND DREBRIN SRC SUBSTRATE CORTACTIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 synapse organization#GO:0050808;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;system development#GO:0048731;cell-substrate junction assembly#GO:0007044;regulation of supramolecular fiber organization#GO:1902903;cell junction organization#GO:0034330;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of actin filament-based process#GO:0032970;focal adhesion assembly#GO:0048041;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell-substrate junction organization#GO:0150115;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of actin filament organization#GO:0110053;cell migration#GO:0016477;multicellular organismal process#GO:0032501;regulation of actin filament polymerization#GO:0030833;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;cell-matrix adhesion#GO:0007160;generation of neurons#GO:0048699;cell adhesion#GO:0007155;regulation of biological quality#GO:0065008;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;cell junction assembly#GO:0034329;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;regulation of anatomical structure size#GO:0090066;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399 cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;lamellipodium#GO:0030027;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;glutamatergic synapse#GO:0098978;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;actin filament#GO:0005884;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000007571.1|UniProtKB=W5MLE0 W5MLE0 PTHR48249:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13-LIKE transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592 LEPOC|Ensembl=ENSLOCG00000007734.1|UniProtKB=W5MLZ5 W5MLZ5 PTHR48078:SF22 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED L-SERINE DEHYDRATASE_L-THREONINE DEAMINASE lyase activity#GO:0016829;catalytic activity#GO:0003824 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;branched-chain amino acid biosynthetic process#GO:0009082 lyase#PC00144;dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000006920.1|UniProtKB=W5MJ05 W5MJ05 MOCS2 PTHR23404:SF2 MOLYBDOPTERIN SYNTHASE RELATED MOLYBDOPTERIN SYNTHASE CATALYTIC SUBUNIT cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009373.1|UniProtKB=W5MSS7 W5MSS7 PTHR22573:SF27 PHOSPHOHEXOMUTASE FAMILY MEMBER PHOSPHOGLUCOMUTASE-LIKE PROTEIN 5 isomerase activity#GO:0016853;intramolecular phosphotransferase activity#GO:0016868;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;striated muscle tissue development#GO:0014706;metabolic process#GO:0008152;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular developmental process#GO:0048869;developmental process#GO:0032502;tissue development#GO:0009888;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;carbohydrate metabolic process#GO:0005975;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;primary metabolic process#GO:0044238;muscle cell development#GO:0055001 adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;sarcolemma#GO:0042383;cell periphery#GO:0071944;cytosol#GO:0005829;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 isomerase#PC00135;metabolite interconversion enzyme#PC00262;mutase#PC00160 LEPOC|Ensembl=ENSLOCG00000010790.1|UniProtKB=W5MXW0 W5MXW0 PTHR12268:SF18 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROTELIN membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell projection#GO:0042995 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006829.1|UniProtKB=W5MIP6 W5MIP6 PTHR46205:SF2 LOQUACIOUS, ISOFORM B INTERFERON-INDUCIBLE DOUBLE-STRANDED RNA-DEPENDENT PROTEIN KINASE ACTIVATOR A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725 regulation of gene silencing by regulatory ncRNA#GO:0060966;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;siRNA processing#GO:0030422;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047 ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 Apoptosis signaling pathway#P00006>PACT#P00280 LEPOC|Ensembl=ENSLOCG00000012051.1|UniProtKB=W5N2H1 W5N2H1 PTHR13856:SF32 VHS DOMAIN CONTAINING PROTEIN FAMILY TARGET OF MYB1 MEMBRANE TRAFFICKING PROTEIN protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000008137.1|UniProtKB=W5MNC6 W5MNC6 CTRB2 PTHR24250:SF68 CHYMOTRYPSIN-RELATED CHYMOTRYPSIN catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein modifying enzyme#PC00260;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000002885.1|UniProtKB=W5M4W4 W5M4W4 PTHR18968:SF166 THIAMINE PYROPHOSPHATE ENZYMES 2-HYDROXYACYL-COA LYASE 2 nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;transketolase or transaldolase activity#GO:0016744;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;proteinogenic amino acid biosynthetic process#GO:0170038;branched-chain amino acid biosynthetic process#GO:0009082;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234 ligase#PC00142;metabolite interconversion enzyme#PC00262 Valine biosynthesis#P02785>Acetolactate synthase#P03216;Isoleucine biosynthesis#P02748>Acetolactate synthase#P02997 LEPOC|Ensembl=ENSLOCG00000009901.1|UniProtKB=W5MUN8 W5MUN8 PTHR11454:SF9 INSULIN/INSULIN GROWTH FACTOR INSULIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896 LEPOC|Ensembl=ENSLOCG00000017543.1|UniProtKB=W5NLY9 W5NLY9 PTHR24410:SF52 HL07962P-RELATED ECTODERM-NEURAL CORTEX PROTEIN 1 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003491.1|UniProtKB=W5M6Y6 W5M6Y6 PTHR21347:SF0 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1L endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010160.1|UniProtKB=W5MVM9 W5MVM9 PTHR20855:SF40 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cellular response to chemical stimulus#GO:0070887;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>AdipoR1/R2#P06706 LEPOC|Ensembl=ENSLOCG00000004653.1|UniProtKB=W5MB14 W5MB14 PTHR32026:SF23 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24 transferase#PC00220;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000011668.1|UniProtKB=W5N149 W5N149 PTHR12895:SF9 DYMECLIN DYMECLIN organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000012584.1|UniProtKB=W5N4D1 W5N4D1 PTHR14740:SF3 CASPASE ACTIVITY AND APOPTOSIS INHIBITOR 1 CASPASE ACTIVITY AND APOPTOSIS INHIBITOR 1 LEPOC|Ensembl=ENSLOCG00000012774.1|UniProtKB=W5N514 W5N514 PTHR43069:SF2 FUMARYLACETOACETASE FUMARYLACETOACETASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;monocarboxylic acid catabolic process#GO:0072329;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phenol-containing compound metabolic process#GO:0018958;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000005603.1|UniProtKB=W5MEF1 W5MEF1 PTHR23430:SF410 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003586.1|UniProtKB=W5M798 W5M798 PTHR10104:SF5 STATHMIN STATHMIN protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;neuron development#GO:0048666;cellular component disassembly#GO:0022411;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;protein-containing complex disassembly#GO:0032984;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;system development#GO:0048731;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;protein depolymerization#GO:0051261;multicellular organismal process#GO:0032501;microtubule polymerization or depolymerization#GO:0031109;regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502 cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 Cytoskeletal regulation by Rho GTPase#P00016>Op18/stathmin#P00513 LEPOC|Ensembl=ENSLOCG00000015501.1|UniProtKB=W5NEL7 W5NEL7 PTHR21530:SF7 PHEROMONE SHUTDOWN PROTEIN TRAB DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010036.1|UniProtKB=W5MV73 W5MV73 PTHR46652:SF3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 LEPOC|Ensembl=ENSLOCG00000001999.1|UniProtKB=W5M1Q2 W5M1Q2 PTHR23129:SF1 ACYL-COENZYME A DIPHOSPHATASE FITM2 ACYL-COENZYME A DIPHOSPHATASE FITM2 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;lipid homeostasis#GO:0055088;lipid storage#GO:0019915;cellular process#GO:0009987;cellular component assembly#GO:0022607;homeostatic process#GO:0042592;lipid droplet organization#GO:0034389;organelle assembly#GO:0070925;chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007672.1|UniProtKB=W5MLR8 W5MLR8 PTHR11183:SF164 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN-1 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;glycogen biosynthetic process#GO:0005978;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;energy reserve metabolic process#GO:0006112;polysaccharide biosynthetic process#GO:0000271;glucan biosynthetic process#GO:0009250;glycogen metabolic process#GO:0005977;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000005502.1|UniProtKB=W5ME37 W5ME37 PTHR12127:SF5 MUCOLIPIN MUCOLIPIN-3 transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;ligand-gated monoatomic cation channel activity#GO:0099094;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267 lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006522.1|UniProtKB=W5MHL9 W5MHL9 PTHR45632:SF5 LD33804P KELCH-LIKE PROTEIN 22 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001798.1|UniProtKB=W5M134 W5M134 PTHR11679:SF35 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 1 protein binding#GO:0005515;syntaxin binding#GO:0019905;SNARE binding#GO:0000149;binding#GO:0005488 establishment of organelle localization#GO:0051656;signaling#GO:0023052;export from cell#GO:0140352;regulation of biological process#GO:0050789;cellular localization#GO:0051641;secretion by cell#GO:0032940;protein transport#GO:0015031;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;regulated exocytosis#GO:0045055;intracellular protein transport#GO:0006886;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;macromolecule localization#GO:0033036;vesicle localization#GO:0051648;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;calcium-ion regulated exocytosis#GO:0017156;intracellular transport#GO:0046907;transport#GO:0006810;synaptic vesicle cycle#GO:0099504 endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Munc18#P05770 LEPOC|Ensembl=ENSLOCG00000014449.1|UniProtKB=W5NAZ2 W5NAZ2 PTHR10749:SF4 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA, SKELETAL MUSCLE ISOFORM transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 LEPOC|Ensembl=ENSLOCG00000010217.1|UniProtKB=W5MVU9 W5MVU9 PTHR46762:SF1 NUCLEOREDOXIN-LIKE PROTEIN 2 NUCLEOREDOXIN-LIKE PROTEIN 2 nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;sensory perception of light stimulus#GO:0050953;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;visual perception#GO:0007601 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010703.1|UniProtKB=W5MXL7 W5MXL7 PTHR13743:SF115 BEIGE/BEACH-RELATED NEUROBEACHIN-LIKE PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011481.1|UniProtKB=W5N0F0 W5N0F0 PTHR19232:SF10 CENTROCORTIN FAMILY MEMBER CEREBELLAR DEGENERATION-RELATED PROTEIN 2-LIKE LEPOC|Ensembl=ENSLOCG00000007482.1|UniProtKB=W5ML27 W5ML27 PTHR46687:SF1 PROTEIN DISPATCHED HOMOLOG 3 PROTEIN DISPATCHED HOMOLOG 3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010755.1|UniProtKB=W5MXR8 W5MXR8 PTHR14958:SF22 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD2 binding#GO:0005488;protein binding#GO:0005515 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004115.1|UniProtKB=W5M964 W5M964 PTHR12317:SF85 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 2-A acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;neutral lipid metabolic process#GO:0006638 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000015846.1|UniProtKB=W5NFU9 W5NFU9 PTHR21020:SF0 ZINC FINGER PROTEIN 800 ZINC FINGER PROTEIN 800 LEPOC|Ensembl=ENSLOCG00000013555.1|UniProtKB=W5N7W0 W5N7W0 PTHR16089:SF24 REST COREPRESSOR COREST PROTEIN-RELATED MITOTIC DEACETYLASE-ASSOCIATED SANT DOMAIN PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000011336.1|UniProtKB=W5MZY0 W5MZY0 PTHR18950:SF0 PROGESTERONE-INDUCED BLOCKING FACTOR 1 PROGESTERONE IMMUNOMODULATORY BINDING FACTOR 1 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000006244.1|UniProtKB=W5MGP9 W5MGP9 PTHR48024:SF10 GEO13361P1-RELATED RNA-BINDING PROTEIN 24 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;positive regulation of biosynthetic process#GO:0009891;regulation of RNA stability#GO:0043487;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;positive regulation of cell differentiation#GO:0045597;negative regulation of RNA metabolic process#GO:0051253 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000017247.1|UniProtKB=W5NL23 W5NL23 PTHR18870:SF7 PROTEIN TAG-278-RELATED PROTEIN FAM184A LEPOC|Ensembl=ENSLOCG00000004127.1|UniProtKB=W5M981 W5M981 PTHR14270:SF0 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 LEPOC|Ensembl=ENSLOCG00000011769.1|UniProtKB=W5N1G4 W5N1G4 PTHR11346:SF26 GALECTIN GALECTIN-3 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;carbohydrate binding#GO:0030246;extracellular matrix binding#GO:0050840;laminin binding#GO:0043236;oligosaccharide binding#GO:0070492;binding#GO:0005488 negative regulation of apoptotic process#GO:0043066;regulation of monoatomic ion transport#GO:0043269;negative regulation of response to stimulus#GO:0048585;cell migration#GO:0016477;regulation of calcium ion transport#GO:0051924;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;leukocyte chemotaxis#GO:0030595;leukocyte migration#GO:0050900;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of metal ion transport#GO:0010959;negative regulation of transport#GO:0051051;cell motility#GO:0048870;regulation of cellular process#GO:0050794;locomotion#GO:0040011;regulation of cell communication#GO:0010646;regulation of extrinsic apoptotic signaling pathway#GO:2001236;negative regulation of cellular component organization#GO:0051129;cellular response to stimulus#GO:0051716;macrophage chemotaxis#GO:0048246;cell chemotaxis#GO:0060326;negative regulation of apoptotic signaling pathway#GO:2001234;chemotaxis#GO:0006935;regulation of apoptotic signaling pathway#GO:2001233;neutrophil migration#GO:1990266;taxis#GO:0042330;response to chemical#GO:0042221;granulocyte migration#GO:0097530;negative regulation of signal transduction#GO:0009968;positive chemotaxis#GO:0050918;negative regulation of programmed cell death#GO:0043069;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of localization#GO:0032879;regulation of transport#GO:0051049;neutrophil chemotaxis#GO:0030593;regulation of endocytosis#GO:0030100;regulation of apoptotic process#GO:0042981;granulocyte chemotaxis#GO:0071621;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;mononuclear cell migration#GO:0071674;regulation of signaling#GO:0023051 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;nucleus#GO:0005634;cell periphery#GO:0071944 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000010873.1|UniProtKB=W5MY65 W5MY65 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000006174.1|UniProtKB=W5MGE9 W5MGE9 PTHR19960:SF30 TEKTIN TEKTIN cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;organelle assembly#GO:0070925;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;9+2 motile cilium#GO:0097729;cilium#GO:0005929;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;motile cilium#GO:0031514;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000012257.1|UniProtKB=W5N373 W5N373 PTHR31353:SF11 FAM98 TRNA-SPLICING LIGASE COMPLEX SUBUNIT FAM98B intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000006231.1|UniProtKB=W5MGL6 W5MGL6 PTHR18976:SF11 APOLIPOPROTEIN APOLIPOPROTEIN A-I enzyme regulator activity#GO:0030234;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;molecular function activator activity#GO:0140677;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;binding#GO:0005488;molecular function regulator activity#GO:0098772;cholesterol transfer activity#GO:0120020;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;sterol transfer activity#GO:0120015;transporter activity#GO:0005215 sterol transport#GO:0015918;sterol metabolic process#GO:0016125;establishment of localization#GO:0051234;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;chemical homeostasis#GO:0048878;transport#GO:0006810;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;lipid transport#GO:0006869;phospholipid transport#GO:0015914;steroid metabolic process#GO:0008202;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;cellular process#GO:0009987;cholesterol efflux#GO:0033344;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;small molecule metabolic process#GO:0044281;organophosphate ester transport#GO:0015748;secondary alcohol metabolic process#GO:1902652;homeostatic process#GO:0042592;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;lipoprotein particle#GO:1990777;plasma lipoprotein particle#GO:0034358;membrane-bounded organelle#GO:0043227;high-density lipoprotein particle#GO:0034364;very-low-density lipoprotein particle#GO:0034361;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 apolipoprotein#PC00052;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000017482.1|UniProtKB=W5NLS8 W5NLS8 PTHR47981:SF17 RAB FAMILY RAS-RELATED PROTEIN RAB-9B hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 cellular component organization#GO:0016043;vesicle fusion#GO:0006906;cytosolic transport#GO:0016482;endocytosis#GO:0006897;organelle assembly#GO:0070925;vacuole organization#GO:0007033;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome organization#GO:0007040;organelle organization#GO:0006996;retrograde transport, endosome to Golgi#GO:0042147;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;transport#GO:0006810;lytic vacuole organization#GO:0080171;phagolysosome assembly#GO:0001845;intracellular transport#GO:0046907;phagocytosis#GO:0006909;endosomal transport#GO:0016197;receptor-mediated endocytosis#GO:0006898;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;phagocytic vesicle#GO:0045335;late endosome#GO:0005770;endomembrane system#GO:0012505 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000006587.1|UniProtKB=W5MHU3 W5MHU3 PTHR15417:SF5 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1C enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184;phosphatase inhibitor#PC00183;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000016799.1|UniProtKB=W5NJF5 W5NJF5 PTHR31535:SF3 FAMILY NOT NAMED REGULATORY PROTEIN ZESTE LEPOC|Ensembl=ENSLOCG00000003485.1|UniProtKB=W5M6X3 W5M6X3 RAB8A PTHR47980:SF99 LD44762P RAS-RELATED PROTEIN RAB-12-RELATED establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;macromolecule localization#GO:0033036;secretion#GO:0046903;localization#GO:0051179;protein localization to cell junction#GO:1902414;organelle assembly#GO:0070925;localization within membrane#GO:0051668;protein localization to synapse#GO:0035418;cellular component organization or biogenesis#GO:0071840;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;exocytosis#GO:0006887;endosomal transport#GO:0016197;protein localization to cell periphery#GO:1990778;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;protein transport#GO:0015031;cilium organization#GO:0044782;secretion by cell#GO:0032940;cell projection organization#GO:0030030;endocytic recycling#GO:0032456;export from cell#GO:0140352;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein localization to membrane#GO:0072657 trans-Golgi network transport vesicle#GO:0030140;endosome#GO:0005768;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008686.1|UniProtKB=W5MQA2 W5MQA2 PTHR35978:SF1 IQ DOMAIN-CONTAINING PROTEIN M IQ DOMAIN-CONTAINING PROTEIN M LEPOC|Ensembl=ENSLOCG00000011355.1|UniProtKB=W5MZZ7 W5MZZ7 PTHR12352:SF25 SECRETED MODULAR CALCIUM-BINDING PROTEIN TESTICAN-1 establishment of protein localization to extracellular region#GO:0035592;localization#GO:0051179;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000017459.1|UniProtKB=W5NLQ5 W5NLQ5 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014910.1|UniProtKB=W5NCK0 W5NCK0 PTHR19354:SF5 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 1-RELATED regulation of biological process#GO:0050789;regulation of dendrite morphogenesis#GO:0048814;modulation of chemical synaptic transmission#GO:0050804;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of cellular component organization#GO:0051128;regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008;regulation of neuron projection development#GO:0010975;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of cell projection organization#GO:0031344;regulation of synaptic plasticity#GO:0048167;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603 neuron projection#GO:0043005;dendritic spine#GO:0043197;postsynapse#GO:0098794;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;synapse#GO:0045202;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;dendrite#GO:0030425;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000000599.1|UniProtKB=W5LX01 W5LX01 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000015854.1|UniProtKB=W5NFW4 W5NFW4 PTHR46461:SF1 KELCH DOMAIN-CONTAINING PROTEIN 3 KELCH DOMAIN-CONTAINING PROTEIN 3 binding#GO:0005488;chromatin binding#GO:0003682 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010310.1|UniProtKB=W5MW74 W5MW74 PTHR11461:SF129 SERINE PROTEASE INHIBITOR, SERPIN SERPIN E3 serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000016805.1|UniProtKB=W5NJG2 W5NJG2 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 LEPOC|Ensembl=ENSLOCG00000004524.1|UniProtKB=W5MAK9 W5MAK9 PTHR24092:SF52 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE FETA lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;lipid transport#GO:0006869;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003654.1|UniProtKB=W5M7J3 W5M7J3 PTHR12323:SF0 SR-RELATED CTD ASSOCIATED FACTOR 6 CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003 cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005493.1|UniProtKB=W5ME54 W5ME54 PTHR12552:SF3 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 42 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000011436.1|UniProtKB=W5N096 W5N096 PTHR10697:SF1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 LEPOC|Ensembl=ENSLOCG00000004840.1|UniProtKB=W5MBR4 W5MBR4 PTHR10502:SF29 ANNEXIN ANNEXIN A11 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phospholipid binding#GO:0005543;ion binding#GO:0043167 cell cycle#GO:0007049;cell division#GO:0051301;cellular process#GO:0009987;cell cycle process#GO:0022402;endocytosis#GO:0006897;phagocytosis#GO:0006909;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000012118.1|UniProtKB=W5N2Q3 W5N2Q3 PTHR14588:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 10 DDB1- AND CUL4-ASSOCIATED FACTOR 10 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000005944.1|UniProtKB=W5MFM4 W5MFM4 PTHR11629:SF22 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;enzyme binding#GO:0019899;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515 metabolic process#GO:0008152;chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;autophagy#GO:0006914;monoatomic cation transmembrane transport#GO:0098655;transmembrane transport#GO:0055085;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;intracellular monoatomic ion homeostasis#GO:0006873;autophagosome maturation#GO:0097352;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion transmembrane transport#GO:0034220;macroautophagy#GO:0016236;biological regulation#GO:0065007;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;monoatomic cation transport#GO:0006812;localization#GO:0051179;catabolic process#GO:0009056;protein-containing complex disassembly#GO:0032984;homeostatic process#GO:0042592 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;ATPase complex#GO:1904949;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000014163.1|UniProtKB=W5N9Y9 W5N9Y9 PTHR12968:SF2 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 2 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;ciliary transition zone#GO:0035869 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001797.1|UniProtKB=W5M125 W5M125 PTHR12888:SF0 PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12 PEROXISOME ASSEMBLY PROTEIN 12 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular process#GO:0009987;peroxisome organization#GO:0007031;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004476.1|UniProtKB=W5MAE9 W5MAE9 PTHR24082:SF39 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 2 sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 Angiogenesis#P00005>PAR#P00192 LEPOC|Ensembl=ENSLOCG00000010406.1|UniProtKB=W5MWK0 W5MWK0 PTHR22589:SF67 CARNITINE O-ACYLTRANSFERASE PEROXISOMAL CARNITINE O-OCTANOYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000014132.1|UniProtKB=W5N9V3 W5N9V3 PTHR19321:SF1 PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED PROTEIN REGULATOR OF CYTOKINESIS 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;nuclear division#GO:0000280;organelle assembly#GO:0070925;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059 cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000014369.1|UniProtKB=W5NAN5 W5NAN5 PTHR22802:SF402 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER E molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000007653.1|UniProtKB=W5MLP1 W5MLP1 PTHR19134:SF499 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE EPSILON catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000001397.1|UniProtKB=W5LZM9 W5LZM9 PTHR24351:SF243 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003395.1|UniProtKB=W5M6P7 W5M6P7 PTHR11973:SF26 CELL SURFACE GLYCOPROTEIN MUC18-RELATED CELL SURFACE GLYCOPROTEIN MUC18 ISOFORM X1-RELATED membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011766.1|UniProtKB=W5N1F9 W5N1F9 PTHR11860:SF111 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000016480.1|UniProtKB=W5NI98 W5NI98 PTHR23055:SF101 CALCIUM BINDING PROTEINS VISININ-LIKE PROTEIN 1 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000008347.1|UniProtKB=W5MP41 W5MP41 PTHR10037:SF278 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 2 SUBUNIT ALPHA transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transmission of nerve impulse#GO:0019226;system process#GO:0003008;sensory perception of pain#GO:0019233;sodium ion transport#GO:0006814;action potential#GO:0001508;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;nervous system process#GO:0050877;sensory perception#GO:0007600;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 cation channel complex#GO:0034703;transporter complex#GO:1990351;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;axon#GO:0030424;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000004340.1|UniProtKB=W5M9Y7 W5M9Y7 PTHR13817:SF55 TITIN PROTEIN SIDEKICK-1 animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;synapse organization#GO:0050808;anatomical structure development#GO:0048856;system development#GO:0048731;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell junction organization#GO:0034330;synapse assembly#GO:0007416;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular component biogenesis#GO:0044085;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000013150.1|UniProtKB=W5N6E0 W5N6E0 PTHR15627:SF8 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000008590.1|UniProtKB=W5MPY7 W5MPY7 PTHR10739:SF19 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE A transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;phospholipid binding#GO:0005543;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphatidylcholine binding#GO:0031210;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;cation binding#GO:0043169 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000014955.1|UniProtKB=W5NCQ5 W5NCQ5 PTHR24238:SF86 G-PROTEIN COUPLED RECEPTOR PROLACTIN-RELEASING PEPTIDE RECEPTOR peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000756.1|UniProtKB=W5LXI0 W5LXI0 PTHR10824:SF42 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COA THIOESTERASE 20-RELATED hydrolase activity#GO:0016787;deacylase activity#GO:0160215;catalytic activity#GO:0003824;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753 microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000015712.1|UniProtKB=W5NFD2 W5NFD2 PTHR46186:SF12 CYSTATIN CYSTATIN C (AMYLOID ANGIOPATHY AND CEREBRAL HEMORRHAGE)-RELATED enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869 vesicle#GO:0031982;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000011753.1|UniProtKB=W5N1F4 W5N1F4 PTHR11036:SF18 SEMAPHORIN SEMAPHORIN-4D molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to chemical#GO:0042221;taxis#GO:0042330;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;chemotaxis#GO:0006935;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;locomotion#GO:0040011;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 membrane-bound signaling molecule#PC00152 Axon guidance mediated by semaphorins#P00007>Sema4D#P00329 LEPOC|Ensembl=ENSLOCG00000007748.1|UniProtKB=W5MM01 W5MM01 PTHR10026:SF45 CYCLIN CYCLIN-L2 enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 kinase modulator#PC00140;kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000014129.1|UniProtKB=W5N9U5 W5N9U5 PTHR35076:SF1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017901.1|UniProtKB=W5NMZ5 W5NMZ5 PTHR24369:SF9 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4 protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 cellular localization#GO:0051641;synaptic membrane adhesion#GO:0099560;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;postsynaptic density organization#GO:0097106;synapse assembly#GO:0007416;excitatory synapse assembly#GO:1904861;cell junction assembly#GO:0034329;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;localization#GO:0051179;anatomical structure development#GO:0048856;postsynaptic specialization organization#GO:0099084;system development#GO:0048731;synapse organization#GO:0050808;localization within membrane#GO:0051668;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;postsynapse organization#GO:0099173;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;intracellular protein localization#GO:0008104;developmental process#GO:0032502;multicellular organismal process#GO:0032501;membrane organization#GO:0061024;biological regulation#GO:0065007;macromolecule localization#GO:0033036 asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;glutamatergic synapse#GO:0098978;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008762.1|UniProtKB=W5MQK6 W5MQK6 PTHR24103:SF611 E3 UBIQUITIN-PROTEIN LIGASE TRIM BBOX AND DUF4200 DOMAIN-CONTAINING PROTEIN-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013401.1|UniProtKB=W5N7A9 W5N7A9 PTHR23268:SF102 T-CELL RECEPTOR BETA CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015355.1|UniProtKB=W5NE39 W5NE39 PTHR21324:SF6 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED TRANSMEMBRANE PROTEIN 150A localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007650.1|UniProtKB=W5MLM0 W5MLM0 PTHR19134:SF539 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 protein phosphatase#PC00195;protein modifying enzyme#PC00260 T cell activation#P00053>CD45#P01329;B cell activation#P00010>CD45#P00396;JAK/STAT signaling pathway#P00038>PTP#P01033 LEPOC|Ensembl=ENSLOCG00000006423.1|UniProtKB=W5MHA0 W5MHA0 PTHR45946:SF5 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-B1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000003677.1|UniProtKB=W5M7P2 W5M7P2 PTHR24416:SF88 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3 kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;nervous system development#GO:0007399;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;ERBB signaling pathway#GO:0038127;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;epidermal growth factor receptor signaling pathway#GO:0007173;multicellular organismal process#GO:0032501;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 signaling receptor complex#GO:0043235;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466 LEPOC|Ensembl=ENSLOCG00000009218.1|UniProtKB=W5MS85 W5MS85 PTHR46925:SF3 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED SUBSTANCE-K RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 positive regulation of locomotion#GO:0040017;regulation of cell motility#GO:2000145;regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of microtubule-based movement#GO:0060632;regulation of reproductive process#GO:2000241;regulation of cellular process#GO:0050794;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147 membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004063.1|UniProtKB=W5M8Z4 W5M8Z4 PTHR11722:SF0 60S RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN EL13 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000002387.1|UniProtKB=W5M354 W5M354 PTHR19143:SF348 FIBRINOGEN/TENASCIN/ANGIOPOEITIN TENASCIN-N cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515 cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;system development#GO:0048731;developmental cell growth#GO:0048588;developmental growth#GO:0048589;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell growth#GO:0016049;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000002255.1|UniProtKB=W5M2M4 W5M2M4 PTHR15970:SF7 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR 2 transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000015862.1|UniProtKB=W5NFX2 W5NFX2 PTHR21738:SF0 RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686 LEPOC|Ensembl=ENSLOCG00000011061.1|UniProtKB=W5MYX7 W5MYX7 PTHR18359:SF0 WD-REPEAT PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000009062.1|UniProtKB=W5MRN6 W5MRN6 PTHR24112:SF39 LEUCINE-RICH REPEAT, ISOFORM F-RELATED F-ACTIN-UNCAPPING PROTEIN LRRC16A regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013571.1|UniProtKB=W5N7X9 W5N7X9 PTHR11036:SF78 SEMAPHORIN SEMAPHORIN-5A signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;regulation of cellular process#GO:0050794;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;developmental growth#GO:0048589;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;axon guidance#GO:0007411;axon development#GO:0061564;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axonogenesis#GO:0007409;neuron development#GO:0048666;developmental growth involved in morphogenesis#GO:0060560;neuron projection extension#GO:1990138;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell growth#GO:0016049;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;growth#GO:0040007;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;axon extension#GO:0048675;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000004642.1|UniProtKB=W5MB01 W5MB01 PTHR45652:SF10 GLIAL FIBRILLARY ACIDIC PROTEIN IF ROD DOMAIN-CONTAINING PROTEIN structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;cellular component assembly#GO:0022607;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;intermediate filament bundle assembly#GO:0045110;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;neuron projection#GO:0043005;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;axon#GO:0030424;intracellular organelle#GO:0043229;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794 cytoskeletal protein#PC00085;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000011480.1|UniProtKB=W5N0E8 W5N0E8 PTHR12322:SF120 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;sex differentiation#GO:0007548;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000000996.1|UniProtKB=W5LYB3 W5LYB3 PTHR15460:SF3 PEROXISOMAL MEMBRANE PROTEIN 4 PEROXISOMAL MEMBRANE PROTEIN 4 peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000005245.1|UniProtKB=W5MD60 W5MD60 PTHR12345:SF18 SYNTENIN RELATED SYNDECAN-BINDING PROTEIN (SYNTENIN) cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018150.1|UniProtKB=W5NNP2 W5NNP2 PTHR11214:SF368 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4 acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;aminoglycan biosynthetic process#GO:0006023;biosynthetic process#GO:0009058 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000003929.1|UniProtKB=W5M8J0 W5M8J0 PTHR11923:SF94 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 LYSOSOME MEMBRANE PROTEIN 2 ISOFORM X1 cargo receptor activity#GO:0038024 intracellular transport#GO:0046907;vacuolar transport#GO:0007034;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;lysosomal transport#GO:0007041;protein localization to vacuole#GO:0072665;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;protein localization to lysosome#GO:0061462;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;endocytosis#GO:0006897;protein localization to organelle#GO:0033365 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000010643.1|UniProtKB=W5MXC0 W5MXC0 PTHR31437:SF1 SREK1IP1 FAMILY MEMBER PROTEIN SREK1IP1 LEPOC|Ensembl=ENSLOCG00000016159.1|UniProtKB=W5NH02 W5NH02 PTHR15160:SF9 VON HIPPEL-LINDAU PROTEIN VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR ubiquitin-like ligase-substrate adaptor activity#GO:1990756;transcription regulator activity#GO:0140110;enzyme-substrate adaptor activity#GO:0140767;transcription corepressor activity#GO:0003714;protein-macromolecule adaptor activity#GO:0030674;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090 regulation of nucleobase-containing compound metabolic process#GO:0019219;proteasomal protein catabolic process#GO:0010498;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;regulation of RNA metabolic process#GO:0051252;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016689.1|UniProtKB=W5NJ20 W5NJ20 PTHR23113:SF178 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 3 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 LEPOC|Ensembl=ENSLOCG00000016716.1|UniProtKB=W5NJ43 W5NJ43 PTHR17008:SF1 MEIOSIS-EXPRESSED GENE 1 PROTEIN MEIOSIS EXPRESSED GENE 1 PROTEIN HOMOLOG cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;sperm motility#GO:0097722;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;spermatogenesis#GO:0007283;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000001591.1|UniProtKB=W5M0C3 W5M0C3 PTHR42650:SF1 TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000018259.1|UniProtKB=W5NP01 W5NP01 PTHR24368:SF62 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 3 anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell adhesion#GO:0007155;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;brain development#GO:0007420;nervous system development#GO:0007399;head development#GO:0060322;cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000002496.1|UniProtKB=W5M3J0 W5M3J0 PTHR11071:SF602 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002214.1|UniProtKB=W5M2G8 W5M2G8 PTHR28641:SF1 FAMILY NOT NAMED MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000006295.1|UniProtKB=W5MGU3 W5MGU3 PTHR45804:SF5 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-C13 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015201.1|UniProtKB=W5NDJ7 W5NDJ7 PTHR42985:SF10 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;lipid localization#GO:0010876;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;fatty acid transport#GO:0015908;monoatomic ion transport#GO:0006811;monocarboxylic acid transport#GO:0015718;sodium ion transport#GO:0006814;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000008667.1|UniProtKB=W5MQ85 W5MQ85 PTHR34761:SF1 NUCLEOLUS AND NEURAL PROGENITOR PROTEIN RIBONUCLEASE MRP SUBUNIT P64 regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signal transduction#GO:0009967;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;positive regulation of response to stimulus#GO:0048584;positive regulation of Notch signaling pathway#GO:0045747;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;regulation of response to stimulus#GO:0048583;positive regulation of signaling#GO:0023056 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000002703.1|UniProtKB=W5M481 W5M481 PTHR44307:SF2 PHOSPHOETHANOLAMINE METHYLTRANSFERASE PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 biosynthetic process#GO:0009058;phosphatidylcholine biosynthetic process#GO:0006656;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000005830.1|UniProtKB=W5MFA0 W5MFA0 PTHR46182:SF1 FI19480P1 DYSLEXIA-ASSOCIATED PROTEIN KIAA0319 cellular process#GO:0009987;nervous system development#GO:0007399;cell differentiation#GO:0030154;cell motility#GO:0048870;multicellular organismal process#GO:0032501;cell migration#GO:0016477;developmental process#GO:0032502;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neurogenesis#GO:0022008;neuron migration#GO:0001764;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000008592.1|UniProtKB=W5MPZ2 W5MPZ2 PTHR23031:SF6 RHOPHILIN RHOPHILIN-1 negative regulation of cytoskeleton organization#GO:0051494;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of biological process#GO:0048519;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008567.1|UniProtKB=W5MPW4 W5MPW4 PTHR11461:SF363 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-1-ANTITRYPSIN PRECURSOR-RELATED peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000002979.1|UniProtKB=W5M560 W5M560 PTHR10177:SF444 CYCLINS CYCLIN-A2 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049 protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;transferase complex#GO:1990234;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 LEPOC|Ensembl=ENSLOCG00000005310.1|UniProtKB=W5MDE9 W5MDE9 PTHR12811:SF3 VACUOLAR PROTEIN SORTING VPS16 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;vacuole fusion, non-autophagic#GO:0042144;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component organization#GO:0016043;vacuole fusion#GO:0097576;vacuole organization#GO:0007033;localization#GO:0051179;cellular localization#GO:0051641 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;lysosomal membrane#GO:0005765;membrane#GO:0016020;vesicle tethering complex#GO:0099023;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017527.1|UniProtKB=W5NLX3 W5NLX3 PTHR24232:SF20 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 regulation of hemostasis#GO:1900046;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of response to wounding#GO:1903034;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;positive regulation of response to stimulus#GO:0048584;regulation of coagulation#GO:0050818;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of wound healing#GO:0061041;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of body fluid levels#GO:0050878;regulation of blood coagulation#GO:0030193;response to stimulus#GO:0050896;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of coagulation#GO:0050820;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Angiogenesis#P00005>PAR#P00192;Blood coagulation#P00011>PAR-1#P00404 LEPOC|Ensembl=ENSLOCG00000014339.1|UniProtKB=W5NAK4 W5NAK4 PTHR48012:SF15 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>GCK#P00268;Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861 LEPOC|Ensembl=ENSLOCG00000016643.1|UniProtKB=W5NIV2 W5NIV2 PTHR20855:SF33 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;response to peptide#GO:1901652 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>AdipoR1/R2#P06706 LEPOC|Ensembl=ENSLOCG00000012491.1|UniProtKB=W5N416 W5N416 PTHR35446:SF2 SI:CH211-175M2.5 CARBOXYMUCONOLACTONE DECARBOXYLASE-LIKE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016291.1|UniProtKB=W5NHJ6 W5NHJ6 PTHR18863:SF7 TSEC-2-RELATED COILED-COIL DOMAIN CONTAINING 170 LEPOC|Ensembl=ENSLOCG00000011842.1|UniProtKB=W5N1Q3 W5N1Q3 PTHR45804:SF3 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-A13 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014332.1|UniProtKB=W5NAI9 W5NAI9 PTHR24390:SF43 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 710 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000006365.1|UniProtKB=W5MH21 W5MH21 PTHR45771:SF13 HOMEOTIC PROTEIN DEFORMED HOMEOBOX C5 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;skeletal system development#GO:0001501;positive regulation of metabolic process#GO:0009893;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anterior/posterior pattern specification#GO:0009952;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;pattern specification process#GO:0007389;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000014570.1|UniProtKB=W5NBB9 W5NBB9 PTHR13345:SF15 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 PROTEIN UXT transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000005553.1|UniProtKB=W5MEA1 W5MEA1 PTHR10117:SF7 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 6 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;single fertilization#GO:0007338;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;fertilization#GO:0009566;reproductive process#GO:0022414;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;sexual reproduction#GO:0019953 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000015112.1|UniProtKB=W5ND88 W5ND88 PTHR45791:SF1 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 1 calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872 LEPOC|Ensembl=ENSLOCG00000008588.1|UniProtKB=W5MPY1 W5MPY1 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000006370.1|UniProtKB=W5MH30 W5MH30 PTHR48017:SF206 OS05G0424000 PROTEIN-RELATED VESICULAR INHIBITORY AMINO ACID TRANSPORTER amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;glycine transmembrane transporter activity#GO:0015187 glycine transport#GO:0015816;localization#GO:0051179;cellular localization#GO:0051641;neutral amino acid transport#GO:0015804;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836 presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;intracellular vesicle#GO:0097708;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;vesicle membrane#GO:0012506;membrane#GO:0016020;somatodendritic compartment#GO:0036477;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;organelle membrane#GO:0031090;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;neuron projection terminus#GO:0044306;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;dendritic tree#GO:0097447;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000006547.1|UniProtKB=W5MHP8 W5MHP8 PTHR12962:SF3 CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED CALCIUM-REGULATED HEAT-STABLE PROTEIN 1 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007116.1|UniProtKB=W5MJR8 W5MJR8 PTHR18860:SF176 14-3-3 PROTEIN 14-3-3 PROTEIN EPSILON protein binding#GO:0005515;binding#GO:0005488 regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624 LEPOC|Ensembl=ENSLOCG00000013775.1|UniProtKB=W5N8M8 W5N8M8 PTHR21053:SF2 TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;nucleoid#GO:0009295;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;mitochondrial nucleoid#GO:0042645;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000009539.1|UniProtKB=W5MTE7 W5MTE7 PTHR21408:SF1 HOMEODOMAIN-ONLY PROTEIN HOMEODOMAIN-ONLY PROTEIN molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;heart development#GO:0007507;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013620.1|UniProtKB=W5N827 W5N827 PTHR21038:SF3 40-2-3 PROTEIN-RELATED UAP56-INTERACTING FACTOR molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-RNA adaptor activity#GO:0140517 establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015783.1|UniProtKB=W5NFM0 W5NFM0 PTHR11220:SF69 HEME-BINDING PROTEIN-RELATED HEME BINDING PROTEIN 2 tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;binding#GO:0005488 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005547.1|UniProtKB=W5ME90 W5ME90 PTHR47633:SF20 IMMUNOGLOBULIN MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE LEPOC|Ensembl=ENSLOCG00000011011.1|UniProtKB=W5MYP9 W5MYP9 PTHR28567:SF2 PROTEIN FAM53A-LIKE ISOFORM X1 PROTEIN FAM53A protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000005884.1|UniProtKB=W5MFE9 W5MFE9 PTHR47977:SF64 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-30 hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;organelle#GO:0043226;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000007403.1|UniProtKB=W5MKT6 W5MKT6 PTHR12466:SF8 CDC73 DOMAIN PROTEIN PARAFIBROMIN RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488 positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000002307.1|UniProtKB=W5M2T8 W5M2T8 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000017313.1|UniProtKB=W5NLA9 W5NLA9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002639.1|UniProtKB=W5M3Z4 W5M3Z4 PTHR12977:SF4 SUPPRESSOR OF VARIEGATION 4-20-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B-RELATED LEPOC|Ensembl=ENSLOCG00000012430.1|UniProtKB=W5N3U2 W5N3U2 PTHR14495:SF2 SHIELDIN COMPLEX SUBUNIT 2 SHIELDIN COMPLEX SUBUNIT 2 regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of response to stress#GO:0080134;regulation of DNA recombination#GO:0000018;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000014256.1|UniProtKB=W5NA92 W5NA92 PTHR10256:SF1 SELENIDE, WATER DIKINASE SELENIDE, WATER DIKINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000017557.1|UniProtKB=W5NM03 W5NM03 PTHR24237:SF36 G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 3 ISOFORM X1 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008244.1|UniProtKB=W5MNP5 W5MNP5 PTHR10582:SF25 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 6 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;calcium ion transport#GO:0006816;inorganic cation import across plasma membrane#GO:0098659;calcium ion transmembrane import into cytosol#GO:0097553;import into cell#GO:0098657;establishment of localization#GO:0051234;calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000001049.1|UniProtKB=W5LYH0 W5LYH0 PTHR24373:SF352 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TSUKUSHI molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017412.1|UniProtKB=W5NLK8 W5NLK8 PTHR10614:SF11 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 1 receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 Gonadotropin-releasing hormone receptor pathway#P06664>IRS-1#P06825;PI3 kinase pathway#P00048>IRS#P01193;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899;CCKR signaling map#P06959>IRS1#P07106;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Interleukin signaling pathway#P00036>IRS1/2#P00980;Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759 LEPOC|Ensembl=ENSLOCG00000001539.1|UniProtKB=W5M074 W5M074 PTHR22599:SF32 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 2A ISOFORM 1-RELATED kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000014451.1|UniProtKB=W5NAX7 W5NAX7 PTHR47225:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 12 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 12 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000016567.1|UniProtKB=W5NIK8 W5NIK8 PTHR16056:SF15 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;spindle pole#GO:0000922;mitochondrion#GO:0005739;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;spindle#GO:0005819;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000014884.1|UniProtKB=W5NCI0 W5NCI0 PTHR12596:SF2 EXPORTIN 4,7-RELATED EXPORTIN-7 ISOFORM X1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein export from nucleus#GO:0006611;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004236.1|UniProtKB=W5M9L0 W5M9L0 PTHR10742:SF429 FLAVIN MONOAMINE OXIDASE PEROXISOMAL N(1)-ACETYL-SPERMINE_SPERMIDINE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056;amine catabolic process#GO:0009310;polyamine catabolic process#GO:0006598;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000014400.1|UniProtKB=W5NAS1 W5NAS1 PTHR11685:SF210 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH2 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008357.1|UniProtKB=W5MP43 W5MP43 PTHR20855:SF39 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR DELTA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005526.1|UniProtKB=W5ME68 W5ME68 PTHR11977:SF29 VILLIN GELSOLIN anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;phosphatidylinositol phosphate binding#GO:1901981 regulation of cellular component organization#GO:0051128;central nervous system development#GO:0007417;cell projection organization#GO:0030030;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure size#GO:0090066;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;anatomical structure development#GO:0048856;system development#GO:0048731;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;regulation of actin filament polymerization#GO:0030833;multicellular organismal process#GO:0032501;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 LEPOC|Ensembl=ENSLOCG00000010404.1|UniProtKB=W5MWJ2 W5MWJ2 PTHR46186:SF12 CYSTATIN CYSTATIN C (AMYLOID ANGIOPATHY AND CEREBRAL HEMORRHAGE)-RELATED enzyme regulator activity#GO:0030234;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 extracellular region#GO:0005576;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000007867.1|UniProtKB=W5MME0 W5MME0 PTHR11818:SF55 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B1-RELATED structural molecule activity#GO:0005198 sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000000087.1|UniProtKB=W5LVE0 W5LVE0 PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;lipid binding#GO:0008289;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;hydrolase activity, acting on ester bonds#GO:0016788;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;cation binding#GO:0043169;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;small molecule binding#GO:0036094;ion binding#GO:0043167 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;phospholipid catabolic process#GO:0009395;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056 endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 LEPOC|Ensembl=ENSLOCG00000010112.1|UniProtKB=W5MVF8 W5MVF8 PTHR25466:SF3 T-LYMPHOCYTE ACTIVATION ANTIGEN PROGRAMMED CELL DEATH 1 LIGAND 1 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;immune response#GO:0006955;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of immune response#GO:0050776;negative regulation of signaling#GO:0023057;immune system process#GO:0002376;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000000680.1|UniProtKB=W5LXA4 W5LXA4 PTHR46532:SF13 MALE FERTILITY FACTOR KL5 DYNEIN AXONEMAL HEAVY CHAIN 5 LEPOC|Ensembl=ENSLOCG00000003506.1|UniProtKB=W5M6Z6 W5M6Z6 PTHR24124:SF8 ANKYRIN REPEAT FAMILY A OCA DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013247.1|UniProtKB=W5N6R5 W5N6R5 PTHR19964:SF10 MULTIPLE PDZ DOMAIN PROTEIN MULTIPLE PDZ DOMAIN PROTEIN cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular process#GO:0009987;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cytoplasm#GO:0005737;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;apical junction complex#GO:0043296;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;tight junction#GO:0070160 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004295.1|UniProtKB=W5M9S1 W5M9S1 PTHR43194:SF2 HYDROLASE ALPHA/BETA FOLD FAMILY PEROXISOMAL MEMBRANE PROTEIN LPX1 hydrolase activity#GO:0016787;triacylglycerol lipase activity#GO:0004806;catalytic activity#GO:0003824;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;acylglycerol metabolic process#GO:0006639;glycerolipid catabolic process#GO:0046503;metabolic process#GO:0008152;triglyceride catabolic process#GO:0019433;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000002045.1|UniProtKB=W5M1W8 W5M1W8 PTHR46457:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;four-way junction DNA binding#GO:0000400;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;telomere organization#GO:0032200;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;nucleobase-containing compound metabolic process#GO:0006139;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987 chromosome#GO:0005694;replication fork#GO:0005657;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011116.1|UniProtKB=W5MZ52 W5MZ52 PTHR11616:SF231 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT PROLINE TRANSPORTER active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943 glycine transport#GO:0015816;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;import into cell#GO:0098657;establishment of localization#GO:0051234;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000008577.1|UniProtKB=W5MPX3 W5MPX3 PTHR11576:SF24 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZP DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009244.1|UniProtKB=W5MSC0 W5MSC0 PTHR11905:SF19 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 19 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 membrane protein ectodomain proteolysis#GO:0006509;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;membrane protein proteolysis#GO:0033619;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000013769.1|UniProtKB=W5N8L9 W5N8L9 EIF3J PTHR21681:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of translational initiation#GO:0006446;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000006939.1|UniProtKB=W5MJ36 W5MJ36 PTHR11461:SF159 SERINE PROTEASE INHIBITOR, SERPIN PLASMA PROTEASE C1 INHIBITOR endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000015440.1|UniProtKB=W5NEE5 W5NEE5 PTHR21531:SF0 LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED PROTEIN LTV1 HOMOLOG nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;ribosome localization#GO:0033750;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;organelle localization#GO:0051640;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;ribosomal small subunit biogenesis#GO:0042274;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003848.1|UniProtKB=W5M883 W5M883 PTHR46534:SF2 IGGFC_BINDING DOMAIN-CONTAINING PROTEIN IGGFC-BINDING PROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000003159.1|UniProtKB=W5M5S4 W5M5S4 PTHR12778:SF9 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED ACETYL-COENZYME A TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005823.1|UniProtKB=W5MF91 W5MF91 PTHR24027:SF432 CADHERIN-23 NEURAL-CADHERIN binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cell migration#GO:0016477;cellular component assembly#GO:0022607;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cell junction organization#GO:0034330;cell motility#GO:0048870;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell adhesion#GO:0007155 adherens junction#GO:0005912;anchoring junction#GO:0070161;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000011558.1|UniProtKB=W5N0P8 W5N0P8 PPP2R5C PTHR10257:SF123 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000004285.1|UniProtKB=W5M9R2 W5M9R2 PTHR10574:SF27 NETRIN/LAMININ-RELATED NETRIN-G2 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;tissue development#GO:0009888;multicellular organismal process#GO:0032501 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 LEPOC|Ensembl=ENSLOCG00000012511.1|UniProtKB=W5N445 W5N445 PTHR24247:SF108 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 5A heterocyclic compound binding#GO:1901363;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;cation binding#GO:0043169;serotonin binding#GO:0051378;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000003763.1|UniProtKB=W5M7Y4 W5M7Y4 PTHR15564:SF7 MACPF DOMAIN-CONTAINING PROTEIN BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 1 neuron differentiation#GO:0030182;negative regulation of cell cycle#GO:0045786;multicellular organism development#GO:0007275;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;nervous system development#GO:0007399;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;generation of neurons#GO:0048699;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;negative regulation of mitotic cell cycle#GO:0045930;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;cell differentiation#GO:0030154;response to stimulus#GO:0050896;central nervous system development#GO:0007417;developmental process#GO:0032502;central nervous system neuron differentiation#GO:0021953;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;system development#GO:0048731;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell body#GO:0044297;intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425 LEPOC|Ensembl=ENSLOCG00000000630.1|UniProtKB=W5LX38 W5LX38 PTHR34766:SF1 UPF0449 PROTEIN C19ORF25 UPF0449 PROTEIN C19ORF25 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890 LEPOC|Ensembl=ENSLOCG00000009522.1|UniProtKB=W5MTD2 W5MTD2 PTHR22855:SF47 ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED METHYLCROTONOYL-COA CARBOXYLASE ligase activity#GO:0016874;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000010435.1|UniProtKB=W5MWN9 W5MWN9 PTHR11785:SF213 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 7 MEMBER 7 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;amino acid transport#GO:0006865;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013918.1|UniProtKB=W5N948 W5N948 PTHR12348:SF29 TSC22 TSC22 DOMAIN FAMILY MEMBER 3 LEPOC|Ensembl=ENSLOCG00000017368.1|UniProtKB=W5NLG4 W5NLG4 PTHR24247:SF183 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M3 neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;acetylcholine receptor activity#GO:0015464;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of muscle system process#GO:0090257;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;response to oxygen-containing compound#GO:1901700;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;regulation of muscle contraction#GO:0006937;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;synaptic signaling#GO:0099536;regulation of multicellular organismal process#GO:0051239;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of system process#GO:0044057;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;regulation of smooth muscle contraction#GO:0006940 cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>mAChR1/3#P01069;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083 LEPOC|Ensembl=ENSLOCG00000011211.1|UniProtKB=W5MZG9 W5MZG9 PTHR12360:SF16 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 TRANSCRIPTIONAL REPRESSOR NF-X1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016789.1|UniProtKB=W5NJF8 W5NJF8 PTHR12634:SF15 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 2 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000008750.1|UniProtKB=W5MQJ4 W5MQJ4 PTHR28359:SF1 ASHWIN TRNA-SPLICING LIGASE COMPLEX SUBUNIT ASW RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000009934.1|UniProtKB=W5MUU0 W5MUU0 PTHR33721:SF3 TRANSMEMBRANE PROTEIN 255B-LIKE TRANSMEMBRANE PROTEIN 255B LEPOC|Ensembl=ENSLOCG00000008335.1|UniProtKB=W5MP17 W5MP17 PTHR10694:SF149 LYSINE-SPECIFIC DEMETHYLASE PROTEIN JUMONJI dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000006748.1|UniProtKB=W5MIE6 W5MIE6 PTHR47979:SF3 DRAB11-RELATED RAS-RELATED PROTEIN RAB-39A catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle organization#GO:0016050;phagolysosome assembly#GO:0001845;phagocytosis#GO:0006909;transport#GO:0006810;lytic vacuole organization#GO:0080171;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;organelle organization#GO:0006996;lysosome organization#GO:0007040;cellular process#GO:0009987;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;endocytosis#GO:0006897;vesicle fusion#GO:0006906;cellular component organization#GO:0016043 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000003980.1|UniProtKB=W5M8P7 W5M8P7 PTHR31075:SF3 CENTROSOMAL PROTEIN OF 85 KDA CENTROSOMAL PROTEIN OF 85 KDA intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002575.1|UniProtKB=W5M3T4 W5M3T4 PTHR12349:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 PALMITOYLTRANSFERASE ZDHHC8 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 regulation of biological process#GO:0050789;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of localization#GO:0032879 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000000053.1|UniProtKB=W5LVA4 W5LVA4 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013064.1|UniProtKB=W5N631 W5N631 PTHR11767:SF24 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 16 ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000008720.1|UniProtKB=W5MQG5 W5MQG5 PTHR10165:SF90 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 4 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644 cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014525.1|UniProtKB=W5NB67 W5NB67 PTHR13793:SF85 PHD FINGER PROTEINS PEREGRIN chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002381.1|UniProtKB=W5M338 W5M338 PTHR21373:SF1 GLUCOSE REPRESSIBLE PROTEIN MAK10 N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066 acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000012921.1|UniProtKB=W5N5K4 W5N5K4 PTHR24240:SF22 OPSIN PHOTOPIGMENT MELANOPSIN-LIKE transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to radiation#GO:0071478;signaling#GO:0023052;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;detection of stimulus#GO:0051606;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011950.1|UniProtKB=W5N248 W5N248 PTHR10856:SF2 CORONIN CORONIN-2A protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;actin filament#GO:0005884;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010182.1|UniProtKB=W5MVQ7 W5MVQ7 PTHR14972:SF6 AGAP011572-PA PROTEIN FAM117B LEPOC|Ensembl=ENSLOCG00000017447.1|UniProtKB=W5NLP3 W5NLP3 PTHR26451:SF860 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009115.1|UniProtKB=W5MRW1 W5MRW1 PTHR10353:SF38 GLYCOSYL HYDROLASE LACTASE_PHLORIZIN HYDROLASE beta-glucosidase activity#GO:0008422;glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944 hydrolase#PC00121;glycosidase#PC00110;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014543.1|UniProtKB=W5NB92 W5NB92 PTHR21049:SF0 RIBOPHORIN I DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000000331.1|UniProtKB=W5LW49 W5LW49 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007675.1|UniProtKB=W5MLQ2 W5MLQ2 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED binding#GO:0005488;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013216.1|UniProtKB=W5N6M1 W5N6M1 PTHR11371:SF36 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE DNA binding#GO:0003677;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788 macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000010070.1|UniProtKB=W5MVB2 W5MVB2 PTHR47992:SF121 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1A phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000015550.1|UniProtKB=W5NET6 W5NET6 PTHR14352:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;chromosome segregation#GO:0007059 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;HAUS complex#GO:0070652;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000006999.1|UniProtKB=W5MJB4 W5MJB4 PTHR18884:SF117 SEPTIN SEPTIN hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;cell division#GO:0051301;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;macromolecule localization#GO:0033036 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoplasm#GO:0005737 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000001924.1|UniProtKB=W5M1I6 W5M1I6 PTHR11358:SF26 ARGINASE/AGMATINASE GUANIDINO ACID HYDROLASE, MITOCHONDRIAL catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000001604.1|UniProtKB=W5M0G2 W5M0G2 PTHR12841:SF6 PROTEIN UNC-50 HOMOLOG PROTEIN UNC-50 HOMOLOG membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000005681.1|UniProtKB=W5MEP9 W5MEP9 PTHR10044:SF79 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 2 enzyme regulator activity#GO:0030234;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of protein modification process#GO:0031399;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of protein ubiquitination#GO:0031396;positive regulation of protein ubiquitination#GO:0031398;negative regulation of apoptotic process#GO:0043066;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 Apoptosis signaling pathway#P00006>c-IAP1,2#P00264;CCKR signaling map#P06959>BIRC2#G07278 LEPOC|Ensembl=ENSLOCG00000010240.1|UniProtKB=W5MVY5 W5MVY5 PTHR24213:SF6 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 2 binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 lamellipodium assembly#GO:0030032;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000015389.1|UniProtKB=W5NE77 W5NE77 PTHR22769:SF56 MUTT/NUDIX HYDROLASE 8-OXO-DGDP PHOSPHATASE NUDT18 nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011604.1|UniProtKB=W5N0U9 W5N0U9 PTHR17537:SF3 TRANSDUCER OF ERBB2 TOB PROTEIN TOB2 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000014660.1|UniProtKB=W5NBQ4 W5NBQ4 PTHR22625:SF69 PLEXIN PLEXIN-B1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular component assembly#GO:0022607;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of axonogenesis#GO:0050770;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell differentiation#GO:0045597;synapse assembly#GO:0007416;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;regulation of cell shape#GO:0008360;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772;animal gross anatomical part developmental process#GO:0160108;positive regulation of cellular component organization#GO:0051130;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;negative regulation of cell adhesion#GO:0007162;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of plasma membrane bounded cell projection organization#GO:0120035;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009918.1|UniProtKB=W5MUS5 W5MUS5 PTHR24103:SF586 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 16-RELATED acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003084.1|UniProtKB=W5M5J0 W5M5J0 PTHR24061:SF418 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011069.1|UniProtKB=W5MYZ4 W5MYZ4 PTHR22640:SF2 STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1 STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000008922.1|UniProtKB=W5MR71 W5MR71 PTHR12694:SF7 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription coregulator activity#GO:0003712;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 LEPOC|Ensembl=ENSLOCG00000003502.1|UniProtKB=W5M6Z3 W5M6Z3 PTHR23220:SF84 INTEGRIN ALPHA INTEGRIN ALPHA-L molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589 cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 LEPOC|Ensembl=ENSLOCG00000004342.1|UniProtKB=W5M9X3 W5M9X3 PTHR24118:SF51 POTE ANKYRIN DOMAIN B-CELL LYMPHOMA 3 PROTEIN transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 membrane traffic protein#PC00150 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859 LEPOC|Ensembl=ENSLOCG00000016893.1|UniProtKB=W5NJS3 W5NJS3 PTHR11412:SF136 MACROGLOBULIN / COMPLEMENT CD109 ANTIGEN endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707 catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000009217.1|UniProtKB=W5MS87 W5MS87 PTHR11132:SF262 SOLUTE CARRIER FAMILY 35 NUCLEOTIDE SUGAR TRANSPORTER SLC35D2 carboxylic acid transmembrane transporter activity#GO:0046943;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleotide-sugar transmembrane transport#GO:0015780;nitrogen compound transport#GO:0071705 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000010086.1|UniProtKB=W5MVC7 W5MVC7 PTHR10390:SF13 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX1 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016000.1|UniProtKB=W5NGE8 W5NGE8 PTHR45983:SF3 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 12 hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 Integrin signalling pathway#P00034>PTP-PEST#P00915 LEPOC|Ensembl=ENSLOCG00000002145.1|UniProtKB=W5M288 W5M288 PTHR13388:SF7 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132E cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;hair cell differentiation#GO:0035315;sensory system development#GO:0048880;cellular process#GO:0009987;epithelium development#GO:0060429;epidermal cell differentiation#GO:0009913;multicellular organismal process#GO:0032501;tissue development#GO:0009888;epithelial cell differentiation#GO:0030855;nervous system development#GO:0007399;sensory organ development#GO:0007423;epidermis development#GO:0008544;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;neurogenesis#GO:0022008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000008359.1|UniProtKB=W5MP53 W5MP53 PTHR15711:SF69 RAP GTPASE-ACTIVATING PROTEIN RAP1 GTPASE ACTIVATING PROTEIN 3 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 axon#GO:0030424;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000001200.1|UniProtKB=W5LYZ6 W5LYZ6 PTHR13848:SF3 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 2 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009451.1|UniProtKB=W5MT27 W5MT27 PTHR24023:SF903 COLLAGEN ALPHA COLLAGEN ALPHA-1(VIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000003050.1|UniProtKB=W5M5E2 W5M5E2 PTHR23308:SF74 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE 1 protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein serine/threonine phosphatase inhibitor activity#GO:0004865;phosphatase inhibitor activity#GO:0019212;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;positive regulation of BMP signaling pathway#GO:0030513;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of BMP signaling pathway#GO:0030510;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;plasma membrane bounded cell projection organization#GO:0120036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear speck#GO:0016607;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA splicing factor#PC00148 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 LEPOC|Ensembl=ENSLOCG00000011667.1|UniProtKB=W5N129 W5N129 PTHR11538:SF41 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000010121.1|UniProtKB=W5MVI4 W5MVI4 PTHR24027:SF419 CADHERIN-23 CADHERIN-17 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell migration#GO:0016477;cell motility#GO:0048870;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000001885.1|UniProtKB=W5M1C8 W5M1C8 PTHR13946:SF16 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription#GO:0006351 nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004715.1|UniProtKB=W5MB89 W5MB89 PTHR12317:SF74 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 2 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000012947.1|UniProtKB=W5N5N4 W5N5N4 PTHR45941:SF4 ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2-LIKE-RELATED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740 LEPOC|Ensembl=ENSLOCG00000006870.1|UniProtKB=W5MIV0 W5MIV0 PTHR43329:SF141 EPOXIDE HYDROLASE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;ether hydrolase activity#GO:0016803;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010095.1|UniProtKB=W5MVE5 W5MVE5 PTHR22746:SF11 RAB6A-GEF COMPLEX PARTNER PROTEIN 1 GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 protein localization to cell junction#GO:1902414;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;intracellular transport#GO:0046907;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;transport#GO:0006810;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular localization#GO:0051641;axonogenesis#GO:0007409;protein transport#GO:0015031;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cytosolic transport#GO:0016482;cell development#GO:0048468;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;intracellular protein transport#GO:0006886;protein localization to synapse#GO:0035418;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;endosomal transport#GO:0016197;neuron projection development#GO:0031175;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;guanyl-nucleotide exchange factor complex#GO:0032045;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000013419.1|UniProtKB=W5N7E0 W5N7E0 PTHR19277:SF164 PENTRAXIN NEURONAL PENTRAXIN 1 LIKE ISOFORM X1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003236.1|UniProtKB=W5M614 W5M614 PTHR31905:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 PROTEIN MIX23 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000003096.1|UniProtKB=W5M5K1 W5M5K1 PTHR23277:SF121 NECTIN-RELATED IMMUNOGLOBULIN SUPERFAMILY MEMBER 21 cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 regulation of signaling#GO:0023051;cell adhesion#GO:0007155;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;homophilic cell-cell adhesion#GO:0007156;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;membrane#GO:0016020;cell-cell junction#GO:0005911;adherens junction#GO:0005912;cell junction#GO:0030054;synaptic membrane#GO:0097060;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;anchoring junction#GO:0070161;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000607.1|UniProtKB=W5LX08 W5LX08 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017171.1|UniProtKB=W5NKR5 W5NKR5 PTHR22960:SF0 MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1 catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;phosphorus-oxygen lyase activity#GO:0016849;lyase activity#GO:0016829 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 LEPOC|Ensembl=ENSLOCG00000013841.1|UniProtKB=W5N8W4 W5N8W4 PTHR11255:SF54 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE EPSILON lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;biological regulation#GO:0065007;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000016177.1|UniProtKB=W5NH29 W5NH29 PTHR32078:SF2 NUCLEAR PROTEIN MDM1 NUCLEAR PROTEIN MDM1 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;regulation of microtubule-based process#GO:0032886;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriolar satellite#GO:0034451;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010898.1|UniProtKB=W5MYB4 W5MYB4 PTHR22803:SF104 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED MACROPHAGE MANNOSE RECEPTOR 1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000017825.1|UniProtKB=W5NMR9 W5NMR9 PTHR23022:SF135 TRANSPOSABLE ELEMENT-RELATED TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000006488.1|UniProtKB=W5MHH7 W5MHH7 PTHR14296:SF16 REMODELING AND SPACING FACTOR 1 REMODELING AND SPACING FACTOR 1 protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular component assembly#GO:0022607;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ISWI-type complex#GO:0031010;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000008316.1|UniProtKB=W5MNZ3 W5MNZ3 PTHR18945:SF195 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;neurotransmitter receptor activity#GO:0030594;passive transmembrane transporter activity#GO:0022803;signaling receptor activity#GO:0038023;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089 cellular component assembly#GO:0022607;monoatomic anion transmembrane transport#GO:0098656;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;chloride transport#GO:0006821;synapse assembly#GO:0007416;signaling#GO:0023052;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;monoatomic anion transport#GO:0006820;chemical synaptic transmission#GO:0007268;chloride transmembrane transport#GO:1902476;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808 signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589;cell junction#GO:0030054;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;dendritic tree#GO:0097447;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000000340.1|UniProtKB=W5LW65 W5LW65 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE LEPOC|Ensembl=ENSLOCG00000015721.1|UniProtKB=W5NFE1 W5NFE1 PTHR13454:SF11 PROTEIN MCM10 HOMOLOG PROTEIN MCM10 HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000017013.1|UniProtKB=W5NK69 W5NK69 PTHR46876:SF1 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LEPOC|Ensembl=ENSLOCG00000017597.1|UniProtKB=W5NM43 W5NM43 PTHR11953:SF2 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT MTR3 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 snRNA 3'-end processing#GO:0034472;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA metabolic process#GO:0016073;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000016182.1|UniProtKB=W5NH37 W5NH37 PTHR13003:SF2 NUP107-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP107 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 biosynthetic process#GO:0009058;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;macromolecule biosynthetic process#GO:0009059;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;gene expression#GO:0010467;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;cellular component organization#GO:0016043;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;protein transport#GO:0015031;protein import into nucleus#GO:0006606 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nuclear pore outer ring#GO:0031080;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006300.1|UniProtKB=W5MGV2 W5MGV2 PTHR10865:SF27 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 2 transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;histone deacetylase binding#GO:0042826;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000013349.1|UniProtKB=W5N744 W5N744 PTHR11947:SF15 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 2, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 TCA cycle#P00051>Pyruvate Dehydrogenase#P01266 LEPOC|Ensembl=ENSLOCG00000001622.1|UniProtKB=W5M0G4 W5M0G4 PTHR17583:SF0 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;macroautophagy#GO:0016236;metabolic process#GO:0008152;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of protein localization to organelle#GO:0072594;pexophagy#GO:0000425;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;establishment of protein localization to vacuole#GO:0072666;catabolic process#GO:0009056;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;late endosome to vacuole transport#GO:0045324;protein localization to vacuole#GO:0072665;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919 transferase complex, transferring phosphorus-containing groups#GO:0061695;endosome#GO:0005768;phosphatidylinositol 3-kinase complex, class III#GO:0035032;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle membrane contact site#GO:0044232;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;extrinsic component of membrane#GO:0019898;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasm#GO:0005737 kinase modulator#PC00140;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007780.1|UniProtKB=W5MM37 W5MM37 PTHR24113:SF12 RAN GTPASE-ACTIVATING PROTEIN 1 RAN GTPASE-ACTIVATING PROTEIN 1 molecular function activator activity#GO:0140677;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;enzyme binding#GO:0019899;binding#GO:0005488;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;intracellular transport#GO:0046907;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009154.1|UniProtKB=W5MS03 W5MS03 PTHR23239:SF358 INTERMEDIATE FILAMENT IF ROD DOMAIN-CONTAINING PROTEIN intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228 intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000015778.1|UniProtKB=W5NFL6 W5NFL6 PTHR23147:SF288 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 7 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear speck#GO:0016607;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000000911.1|UniProtKB=W5LY12 W5LY12 PTHR14879:SF2 CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RIFIFYLIN transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of cell communication#GO:0010648;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of extrinsic apoptotic signaling pathway#GO:2001236;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016953.1|UniProtKB=W5NK00 W5NK00 PTHR46716:SF1 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;JNK cascade#GO:0007254;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;MAPK cascade#GO:0000165;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MEK#P00864;TGF-beta signaling pathway#P00052>TAK#P01285;Interleukin signaling pathway#P00036>MEK#P00984;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Gonadotropin-releasing hormone receptor pathway#P06664>TAK1#P06799;p38 MAPK pathway#P05918>TAK1#P06037;Toll receptor signaling pathway#P00054>TAK1#P01370 LEPOC|Ensembl=ENSLOCG00000002894.1|UniProtKB=W5M4U9 W5M4U9 PTHR13139:SF2 RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN ROQUIN-2 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;RNA binding#GO:0003723;ubiquitin-like protein transferase activity#GO:0019787;double-stranded RNA binding#GO:0003725;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;post-translational protein modification#GO:0043687;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;modification-dependent protein catabolic process#GO:0019941;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;protein ubiquitination#GO:0016567;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;protein catabolic process#GO:0030163;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000006433.1|UniProtKB=W5MHB0 W5MHB0 PTHR23247:SF2 NY-REN-41 ANTIGEN L15 -RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 34 LEPOC|Ensembl=ENSLOCG00000018277.1|UniProtKB=W5NP19 W5NP19 PTHR21196:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 snRNA binding#GO:0017069;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123 organelle lumen#GO:0043233;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000005080.1|UniProtKB=W5MCK8 W5MCK8 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014262.1|UniProtKB=W5NAA1 W5NAA1 PTHR31553:SF3 NF-KAPPA-B ESSENTIAL MODULATOR NF-KAPPA-B ESSENTIAL MODULATOR protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;modification-dependent protein binding#GO:0140030 positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911 LEPOC|Ensembl=ENSLOCG00000006740.1|UniProtKB=W5MIG1 W5MIG1 PTHR13931:SF2 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 B catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000003330.1|UniProtKB=W5M6C9 W5M6C9 PTHR24126:SF69 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 65-LIKE LEPOC|Ensembl=ENSLOCG00000003856.1|UniProtKB=W5M896 W5M896 PTHR12011:SF264 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018148.1|UniProtKB=W5NNP0 W5NNP0 PTHR24225:SF81 CHEMOTACTIC RECEPTOR CHEMERIN-LIKE RECEPTOR 1 signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;regulation of biological quality#GO:0065008;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;immune response-regulating signaling pathway#GO:0002764;immune response-activating signaling pathway#GO:0002757;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008739.1|UniProtKB=W5MQH6 W5MQH6 PTHR11829:SF211 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000008142.1|UniProtKB=W5MNC5 W5MNC5 PTHR20859:SF22 INTERFERON/INTERLEUKIN RECEPTOR TISSUE FACTOR transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Blood coagulation#P00011>Tissue Factor#P00450;Angiogenesis#P00005>TF#P00191 LEPOC|Ensembl=ENSLOCG00000000894.1|UniProtKB=W5LXY6 W5LXY6 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013296.1|UniProtKB=W5N6X5 W5N6X5 PTHR10615:SF222 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT7 protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;acetyltransferase activity#GO:0016407;binding#GO:0005488;transcription regulator activity#GO:0140110;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;histone acetyltransferase activity#GO:0004402;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137 LEPOC|Ensembl=ENSLOCG00000000313.1|UniProtKB=W5LW51 W5LW51 PTHR14905:SF18 NG37 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING 10, TANDEM DUPLICATE 1-RELATED LEPOC|Ensembl=ENSLOCG00000001154.1|UniProtKB=W5LYU2 W5LYU2 PTHR22599:SF10 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3A molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000002231.1|UniProtKB=W5M2K5 W5M2K5 PTHR12622:SF21 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX2-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;catabolic process#GO:0009056;cell surface receptor signaling pathway#GO:0007166;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;signal transduction#GO:0007165;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000000203.1|UniProtKB=W5LVR9 W5LVR9 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000004660.1|UniProtKB=W5MB19 W5MB19 PTHR45652:SF10 GLIAL FIBRILLARY ACIDIC PROTEIN IF ROD DOMAIN-CONTAINING PROTEIN structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;intermediate filament cytoskeleton organization#GO:0045104;cellular component assembly#GO:0022607;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;intermediate filament bundle assembly#GO:0045110;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;neuron projection#GO:0043005;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000001700.1|UniProtKB=W5M0Q7 W5M0Q7 RTEL1 PTHR11472:SF34 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER REGULATOR OF TELOMERE ELONGATION HELICASE 1 ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;purine ribonucleotide binding#GO:0032555;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;DNA helicase activity#GO:0003678;carbohydrate derivative binding#GO:0097367;nucleic acid conformation isomerase activity#GO:0120545;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;helicase activity#GO:0004386;nucleotide binding#GO:0000166;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of DNA recombination#GO:0000018;regulation of cellular response to stress#GO:0080135;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;regulation of cellular component biogenesis#GO:0044087;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of cellular component organization#GO:0051128;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;chromosome organization#GO:0051276;regulation of telomere maintenance#GO:0032204;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;telomere organization#GO:0032200;regulation of double-strand break repair#GO:2000779;nucleic acid metabolic process#GO:0090304;negative regulation of DNA recombination#GO:0045910;primary metabolic process#GO:0044238;negative regulation of cellular component organization#GO:0051129;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001787.1|UniProtKB=W5M120 W5M120 PTHR21240:SF27 2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;lyase activity#GO:0016829 metabolic process#GO:0008152;cellular process#GO:0009987;secondary metabolic process#GO:0019748 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 LEPOC|Ensembl=ENSLOCG00000000111.1|UniProtKB=W5LVG7 W5LVG7 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000004362.1|UniProtKB=W5MA25 W5MA25 PTHR11533:SF156 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1 exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235 peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;catabolic process#GO:0009056;cellular process#GO:0009987;peptide catabolic process#GO:0043171;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000005325.1|UniProtKB=W5MDF4 W5MDF4 PTHR43028:SF10 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 INOSITOL MONOPHOSPHATASE 3 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791 tissue development#GO:0009888;chondrocyte differentiation#GO:0002062;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;connective tissue development#GO:0061448;developmental process#GO:0032502;cell differentiation#GO:0030154;cell development#GO:0048468;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;cartilage development#GO:0051216;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000008176.1|UniProtKB=W5MNG4 W5MNG4 PTHR12154:SF4 GLYCOSYL TRANSFERASE-RELATED UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007464.1|UniProtKB=W5ML02 W5ML02 PTHR11709:SF233 MULTI-COPPER OXIDASE FERROXIDASE HEPHL1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722;catalytic activity#GO:0003824 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000012341.1|UniProtKB=W5N3I4 W5N3I4 PTHR10218:SF230 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-3 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897 G-protein#PC00020;heterotrimeric G-protein#PC00117 Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Enkephalin release#P05913>G-Protein (i)#P05974;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;PI3 kinase pathway#P00048>Galpha#P01199;Endogenous cannabinoid signaling#P05730>Galpha#P05751;Opioid proenkephalin pathway#P05915>G-protein#P05994;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Nicotine pharmacodynamics pathway#P06587>GNAI#P06609;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828 LEPOC|Ensembl=ENSLOCG00000002432.1|UniProtKB=W5M397 W5M397 PTHR25465:SF30 B-BOX DOMAIN CONTAINING FINTRIM FAMILY, MEMBER 82 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005833.1|UniProtKB=W5MF87 W5MF87 PTHR12904:SF23 FAMILY NOT NAMED PROTEIN ZER-1 HOMOLOG protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000006148.1|UniProtKB=W5MGC4 W5MGC4 PTHR24012:SF786 RNA BINDING PROTEIN RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000675.1|UniProtKB=W5LX90 W5LX90 PTHR10989:SF11 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN-INDUCED GENE 1 PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;monocarboxylic acid catabolic process#GO:0072329;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042 LEPOC|Ensembl=ENSLOCG00000005874.1|UniProtKB=W5MFD2 W5MFD2 PTHR10279:SF8 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001810.1|UniProtKB=W5M133 W5M133 PTHR46894:SF1 TSC22 DOMAIN FAMILY PROTEIN 2 TSC22 DOMAIN FAMILY PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000005627.1|UniProtKB=W5MEI3 W5MEI3 PTHR21191:SF8 AQUAPORIN AQUAPORIN-12A-RELATED channel activity#GO:0015267;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cellular component organization or biogenesis#GO:0071840;intracellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;regulation of cell size#GO:0008361;cellular homeostasis#GO:0019725;regulation of anatomical structure size#GO:0090066;chemical homeostasis#GO:0048878;biological regulation#GO:0065007;homeostatic process#GO:0042592;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000003446.1|UniProtKB=W5M6U6 W5M6U6 PTHR13064:SF2 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER TRANSMEMBRANE PROTEIN 9B LEPOC|Ensembl=ENSLOCG00000006537.1|UniProtKB=W5MHN9 W5MHN9 PTHR19969:SF23 SH2-SH3 ADAPTOR PROTEIN-RELATED CRK-LIKE PROTEIN signaling adaptor activity#GO:0035591;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;signaling receptor binding#GO:0005102;binding#GO:0005488;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;protein-macromolecule adaptor activity#GO:0030674;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090 positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;cell migration#GO:0016477;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Crk#P00207;Integrin signalling pathway#P00034>Crk#P00933 LEPOC|Ensembl=ENSLOCG00000011857.1|UniProtKB=W5N1S2 W5N1S2 EVX1 PTHR46294:SF2 SEGMENTATION PROTEIN EVEN-SKIPPED HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000013713.1|UniProtKB=W5N8G8 W5N8G8 PTHR23127:SF0 CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077;centromere DNA-binding protein#PC00071 LEPOC|Ensembl=ENSLOCG00000007258.1|UniProtKB=W5MK80 W5MK80 PTHR12247:SF88 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 3 protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000002610.1|UniProtKB=W5M400 W5M400 PTHR24095:SF146 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000016817.1|UniProtKB=W5NJH6 W5NJH6 PTHR12081:SF19 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000001468.1|UniProtKB=W5M029 W5M029 PTHR24115:SF380 KINESIN-RELATED KINESIN HEAVY CHAIN ISOFORM 5C hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;plus-end-directed microtubule motor activity#GO:0008574;protein binding#GO:0005515;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787 developmental process#GO:0032502;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;neuron projection guidance#GO:0097485;vesicle cytoskeletal trafficking#GO:0099518;mitochondrion localization#GO:0051646;neurogenesis#GO:0022008;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;vesicle localization#GO:0051648;axon development#GO:0061564;axo-dendritic transport#GO:0008088;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;axonal transport#GO:0098930;organelle localization#GO:0051640;system development#GO:0048731;anterograde axonal transport#GO:0008089;localization#GO:0051179;anatomical structure development#GO:0048856;microtubule-based movement#GO:0007018;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;neuron projection development#GO:0031175;synaptic vesicle transport#GO:0048489;establishment of vesicle localization#GO:0051650;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;organelle transport along microtubule#GO:0072384;synaptic vesicle localization#GO:0097479;microtubule-based transport#GO:0099111;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular localization#GO:0051641;anatomical structure morphogenesis#GO:0009653;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;establishment of organelle localization#GO:0051656 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000010998.1|UniProtKB=W5MYN5 W5MYN5 COQ6 PTHR43876:SF7 UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001943.1|UniProtKB=W5M1J0 W5M1J0 PTHR24233:SF4 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 171 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012395.1|UniProtKB=W5N3Q4 W5N3Q4 ELOVL6 PTHR11157:SF68 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 3 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000009810.1|UniProtKB=W5MUC6 W5MUC6 RNF168 PTHR23328:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF168 acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;chromatin binding#GO:0003682;nucleosome binding#GO:0031491;ubiquitin-protein transferase activity#GO:0004842;protein-containing complex binding#GO:0044877;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000000743.1|UniProtKB=W5LXG7 W5LXG7 PTHR23226:SF438 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 436 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000015999.1|UniProtKB=W5NGE5 W5NGE5 PTHR46094:SF1 INTEGRATOR COMPLEX SUBUNIT 9 INTEGRATOR COMPLEX SUBUNIT 9 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;integrator complex#GO:0032039;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009370.1|UniProtKB=W5MSS2 W5MSS2 PTHR11042:SF166 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2AK3#P06813 LEPOC|Ensembl=ENSLOCG00000007891.1|UniProtKB=W5MMH4 W5MMH4 PTHR13407:SF1 RNF121 PROTEIN E3 UBIQUITIN LIGASE RNF121 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000243.1|UniProtKB=W5LVW2 W5LVW2 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008700.1|UniProtKB=W5MQC7 W5MQC7 PTHR31626:SF2 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171B LEPOC|Ensembl=ENSLOCG00000011671.1|UniProtKB=W5N134 W5N134 PTHR23503:SF25 SOLUTE CARRIER FAMILY 2 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 transport#GO:0006810;carbohydrate transport#GO:0008643;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;import across plasma membrane#GO:0098739 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000003814.1|UniProtKB=W5M846 W5M846 PTHR23503:SF1 SOLUTE CARRIER FAMILY 2 MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 import across plasma membrane#GO:0098739;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;localization#GO:0051179;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000007424.1|UniProtKB=W5MKV4 W5MKV4 PTHR12845:SF6 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 19 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 wound healing#GO:0042060;regulation of actin filament-based process#GO:0032970;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000002877.1|UniProtKB=W5M4S7 W5M4S7 PTHR10942:SF0 LEISHMANOLYSIN-LIKE PEPTIDASE LEISHMANOLYSIN-LIKE PEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002438.1|UniProtKB=W5M3A3 W5M3A3 PTHR13164:SF3 CALICYLIN BINDING PROTEIN CALCYCLIN-BINDING PROTEIN enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;heart development#GO:0007507;system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016468.1|UniProtKB=W5NI83 W5NI83 PTHR22961:SF15 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 2 protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of ubiquitin-dependent protein catabolic process#GO:2000058 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013871.1|UniProtKB=W5N915 W5N915 PTHR42780:SF1 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000016171.1|UniProtKB=W5NH16 W5NH16 PTHR12696:SF1 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;protein-containing complex assembly#GO:0065003;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;cellular component assembly#GO:0022607;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012000.1|UniProtKB=W5N298 W5N298 PTHR15924:SF9 CLE TRNA-SPLICING LIGASE COMPLEX SUBUNIT RTRAF nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000014684.1|UniProtKB=W5NBR9 W5NBR9 PTHR46174:SF1 CXXC-TYPE ZINC FINGER PROTEIN 1 CXXC-TYPE ZINC FINGER PROTEIN 1 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000001901.1|UniProtKB=W5M1E4 W5M1E4 PTHR22691:SF8 YEAST SPT2-RELATED PROTEIN SPT2 HOMOLOG histone binding#GO:0042393;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;protein binding#GO:0005515 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;transcription by RNA polymerase I#GO:0006360;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;nucleosome organization#GO:0034728;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000018070.1|UniProtKB=W5NNG2 W5NNG2 PTHR23227:SF87 BUCENTAUR RELATED PROTEIN CFDP2 LEPOC|Ensembl=ENSLOCG00000013998.1|UniProtKB=W5N9E8 W5N9E8 PTHR43599:SF11 MULTIFUNCTIONAL PROTEIN ADE2 BIFUNCTIONAL PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE_PHOSPHORIBOSYLAMINOIMIDAZOLE SUCCINOCARBOXAMIDE SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000006970.1|UniProtKB=W5MJ75 W5MJ75 PTHR43671:SF92 SERINE/THREONINE-PROTEIN KINASE NEK SERINE_THREONINE-PROTEIN KINASE NEK10 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of cell cycle phase transition#GO:1901987 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;protein kinase complex#GO:1902911 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017253.1|UniProtKB=W5NL32 W5NL32 PTHR11984:SF105 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;regulation of biological process#GO:0050789;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell junction#GO:0030054;anchoring junction#GO:0070161 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000001835.1|UniProtKB=W5M191 W5M191 PTHR22809:SF5 METHYLTRANSFERASE-RELATED TRNA N(3)-CYTIDINE METHYLTRANSFERASE METTL6 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000000023.1|UniProtKB=W5LV69 W5LV69 PTHR12280:SF23 PANTOTHENATE KINASE PANTOTHENATE KINASE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 LEPOC|Ensembl=ENSLOCG00000000217.1|UniProtKB=W5LVT6 W5LVT6 PTHR44027:SF6 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5B chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012948.1|UniProtKB=W5N5N5 W5N5N5 PTHR10918:SF2 HOMER HOMER PROTEIN HOMOLOG 2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;sensory perception of sound#GO:0007605;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;nervous system process#GO:0050877;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of monoatomic ion transport#GO:0043269;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;cell surface receptor signaling pathway#GO:0007166;regulation of transport#GO:0051049;system process#GO:0003008;regulation of localization#GO:0032879 cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cytoplasm#GO:0005737;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000012801.1|UniProtKB=W5N542 W5N542 ABHD17C PTHR12277:SF55 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17C catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of postsynapse organization#GO:0099175;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of synapse organization#GO:0050807;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000012061.1|UniProtKB=W5N2I0 W5N2I0 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000000438.1|UniProtKB=W5LWH4 W5LWH4 PTHR48051:SF80 FAMILY NOT NAMED SERINE_THREONINE-PROTEIN KINASE PATS1 ISOFORM X2-RELATED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004595.1|UniProtKB=W5MAU2 W5MAU2 PTHR46652:SF7 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 42 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000001227.1|UniProtKB=W5LZ33 W5LZ33 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000007729.1|UniProtKB=W5MLX5 W5MLX5 PTHR45696:SF10 60S ACIDIC RIBOSOMAL PROTEIN P1 LARGE RIBOSOMAL SUBUNIT PROTEIN P1 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;structural molecule activity#GO:0005198;protein kinase activator activity#GO:0030295;structural constituent of ribosome#GO:0003735;enzyme activator activity#GO:0008047;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488;kinase activator activity#GO:0019209 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000005965.1|UniProtKB=W5MFP6 W5MFP6 PTHR12585:SF54 SCC1 / RAD21 FAMILY MEMBER DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;chromosome organization#GO:0051276;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;sister chromatid cohesion#GO:0007062;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000009126.1|UniProtKB=W5MRW5 W5MRW5 PTHR33861:SF4 PROTEIN CBG18333 MEIOSIS-SPECIFIC COILED-COIL DOMAIN-CONTAINING PROTEIN MEIOC negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;RNA stabilization#GO:0043489;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;nuclear division#GO:0000280;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;meiotic cell cycle#GO:0051321;male meiotic nuclear division#GO:0007140;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;organelle fission#GO:0048285;positive regulation of biosynthetic process#GO:0009891;sexual reproduction#GO:0019953;regulation of RNA stability#GO:0043487;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell cycle#GO:0007049;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;meiotic nuclear division#GO:0140013;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;biological regulation#GO:0065007;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008405.1|UniProtKB=W5MPA5 W5MPA5 PTHR19923:SF0 WD40 REPEAT PROTEINPRL1/PRL2-RELATED PLEIOTROPIC REGULATOR 1 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000008474.1|UniProtKB=W5MPK4 W5MPK4 PTHR13220:SF11 TIMELESS INTERACTING-RELATED TIMELESS-INTERACTING PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;DNA metabolic process#GO:0006259;negative regulation of DNA-templated DNA replication#GO:2000104;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;DNA replication#GO:0006260;regulation of DNA-templated DNA replication#GO:0090329;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;cellular response to stress#GO:0033554;regulation of DNA replication#GO:0006275;DNA-templated DNA replication#GO:0006261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010084.1|UniProtKB=W5MVC6 W5MVC6 PTHR10937:SF10 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 2 transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740 UDP-N-acetylglucosamine biosynthetic process#GO:0006048;UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225 transaminase#PC00216 N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042;O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051 LEPOC|Ensembl=ENSLOCG00000005119.1|UniProtKB=W5MCQ2 W5MCQ2 PTHR11486:SF31 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 4 fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102 response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;multicellular organism development#GO:0007275;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;system development#GO:0048731;positive regulation of cellular process#GO:0048522;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;regulation of cell migration#GO:0030334;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000016111.1|UniProtKB=W5NGU2 W5NGU2 PTHR35254:SF1 STIMULATED BY RETINOIC ACID GENE 8 PROTEIN HOMOLOG STIMULATED BY RETINOIC ACID GENE 8 PROTEIN HOMOLOG LEPOC|Ensembl=ENSLOCG00000001138.1|UniProtKB=W5LYU7 W5LYU7 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000001392.1|UniProtKB=W5LZM8 W5LZM8 PTHR24253:SF89 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 2 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016559.1|UniProtKB=W5NIJ1 W5NIJ1 PTHR12917:SF17 ASPARTYL PROTEASE DDI-RELATED NUCLEAR RECEPTOR-INTERACTING PROTEIN 2 aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007176.1|UniProtKB=W5MJX9 W5MJX9 PTHR11474:SF124 TYROSINASE FAMILY MEMBER TYROSINASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152;pigment biosynthetic process#GO:0046148;melanin biosynthetic process#GO:0042438;secondary metabolic process#GO:0019748;pigment metabolic process#GO:0042440;phenol-containing compound biosynthetic process#GO:0046189;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;biosynthetic process#GO:0009058 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;melanosome#GO:0042470;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000009627.1|UniProtKB=W5MTQ3 W5MTQ3 PTHR10742:SF364 FLAVIN MONOAMINE OXIDASE AMINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576;amine metabolic process#GO:0009308;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;polyamine catabolic process#GO:0006598;metabolic process#GO:0008152;amine catabolic process#GO:0009310 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000011424.1|UniProtKB=W5N093 W5N093 PTHR20856:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;DNA-templated transcription elongation#GO:0006354 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000007327.1|UniProtKB=W5MKJ2 W5MKJ2 PTHR19134:SF208 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE T phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;biological regulation#GO:0065007;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002103.1|UniProtKB=W5M228 W5M228 PTHR24231:SF47 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 82-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009407.1|UniProtKB=W5MSX1 W5MSX1 PTHR10562:SF131 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 2-RELATED protein binding#GO:0005515;enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488 protein sumoylation#GO:0016925;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 p53 pathway#P00059>Sumo-1 ligase#P04635 LEPOC|Ensembl=ENSLOCG00000012830.1|UniProtKB=W5N582 W5N582 PTHR24274:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009023.1|UniProtKB=W5MRK0 W5MRK0 PTHR24278:SF25 COAGULATION FACTOR COAGULATION FACTOR IX serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000003939.1|UniProtKB=W5M8J7 W5M8J7 PTHR45762:SF2 ZINC FINGER RNA-BINDING PROTEIN ZINC FINGER RNA-BINDING PROTEIN 2 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010800.1|UniProtKB=W5MXY1 W5MXY1 PTHR13723:SF37 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 5 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;external encapsulating structure organization#GO:0045229;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000012168.1|UniProtKB=W5N2Y5 W5N2Y5 PTHR24180:SF3 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-1 glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 regulation of response to stimulus#GO:0048583;regulation of chromosome organization#GO:0033044;regulation of telomere maintenance#GO:0032204;intracellular protein localization#GO:0008104;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;localization#GO:0051179;positive regulation of DNA metabolic process#GO:0051054;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;positive regulation of biological process#GO:0048518;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of macromolecule metabolic process#GO:0010604;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;positive regulation of signaling#GO:0023056;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular component organization#GO:0051128 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 kinase modulator#PC00140;kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000013982.1|UniProtKB=W5N9D2 W5N9D2 PTHR12659:SF2 RHO-TYPE GTPASE ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 7 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;actin filament-based process#GO:0030029;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;actin cytoskeleton organization#GO:0030036;regulation of cell communication#GO:0010646;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 cell junction#GO:0030054;anchoring junction#GO:0070161;membrane microdomain#GO:0098857;cellular anatomical structure#GO:0110165;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;membrane#GO:0016020;membrane raft#GO:0045121 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000008435.1|UniProtKB=W5MPE8 W5MPE8 PTHR24006:SF727 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 42 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;regulation of protein stability#GO:0031647;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000015196.1|UniProtKB=W5NDJ3 W5NDJ3 PTHR14063:SF1 PROTEIN LIN-7 HOMOLOG PDZ DOMAIN-CONTAINING PROTEIN 11 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;export from cell#GO:0140352;establishment of organelle localization#GO:0051656;regulation of cellular component organization#GO:0051128;regulation of synapse organization#GO:0050807;regulation of biological quality#GO:0065008;secretion by cell#GO:0032940;cellular localization#GO:0051641;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle transport#GO:0048489;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of growth#GO:0040008;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell junction assembly#GO:1901888;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;signal release#GO:0023061;secretion#GO:0046903;regulation of synapse structure or activity#GO:0050803;cell communication#GO:0007154;localization#GO:0051179;vesicle localization#GO:0051648;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of synapse assembly#GO:0051963;transport#GO:0006810;establishment of localization#GO:0051234 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;anchoring junction#GO:0070161;cell junction#GO:0030054 cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000010471.1|UniProtKB=W5MWS8 W5MWS8 PTHR13296:SF0 BCAS2 PROTEIN PRE-MRNA-SPLICING FACTOR SPF27 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000017048.1|UniProtKB=W5NKA9 W5NKA9 PTHR10634:SF67 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000004814.1|UniProtKB=W5MBM3 W5MBM3 PTHR23102:SF24 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000014103.1|UniProtKB=W5N9R7 W5N9R7 PTHR12281:SF8 RP42 RELATED DCN1-LIKE PROTEIN 4 protein binding#GO:0005515;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of protein modification process#GO:0031399;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001125.1|UniProtKB=W5LYQ9 W5LYQ9 IL12B PTHR48485:SF3 INTERLEUKIN-12 SUBUNIT BETA-RELATED INTERLEUKIN-12 SUBUNIT BETA cytokine activity#GO:0005125;cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;biological regulation#GO:0065007;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 LEPOC|Ensembl=ENSLOCG00000008436.1|UniProtKB=W5MPF1 W5MPF1 PTHR12266:SF39 NA+/CA2+ K+ INDEPENDENT EXCHANGER MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;homeostatic process#GO:0042592;metal ion transport#GO:0030001;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000015635.1|UniProtKB=W5NF44 W5NF44 PTHR22625:SF34 PLEXIN PLEXIN-A4 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;regulation of axonogenesis#GO:0050770;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;positive regulation of axonogenesis#GO:0050772;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;signaling#GO:0023052;positive regulation of nervous system development#GO:0051962;cell projection organization#GO:0030030;cell differentiation#GO:0030154;developmental process#GO:0032502;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of cell adhesion#GO:0007162;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of nervous system development#GO:0051960;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;neuron differentiation#GO:0030182;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cell shape#GO:0008360;positive regulation of multicellular organismal process#GO:0051240;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;synapse assembly#GO:0007416;cell morphogenesis#GO:0000902;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;axon guidance#GO:0007411;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005262.1|UniProtKB=W5MD77 W5MD77 PTHR14826:SF3 ANGIOMOTIN ANGIOMOTIN-LIKE PROTEIN 2 cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;establishment of cell polarity#GO:0030010;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;system development#GO:0048731;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;tube development#GO:0035295;cell migration#GO:0016477;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of cell migration#GO:0030334;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;blood vessel morphogenesis#GO:0048514;cellular component organization#GO:0016043;angiogenesis#GO:0001525;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;hippo signaling#GO:0035329;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000014146.1|UniProtKB=W5N9W8 W5N9W8 PTHR46246:SF1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013227.1|UniProtKB=W5N6N3 W5N6N3 PTHR35826:SF1 PROTEIN ATP6V1FNB-LIKE PROTEIN SPMIP1 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000001646.1|UniProtKB=W5M0I7 W5M0I7 PTHR10390:SF73 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX7 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;sensory system development#GO:0048880;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;sensory organ development#GO:0007423;visual system development#GO:0150063;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;eye development#GO:0001654;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000007894.1|UniProtKB=W5MMI5 W5MMI5 PTHR24412:SF155 KELCH PROTEIN KELCH-LIKE PROTEIN 2 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006352.1|UniProtKB=W5MH06 W5MH06 PTHR22923:SF103 CEREBELLIN-RELATED CEREBELLIN 20-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010919.1|UniProtKB=W5MYD1 W5MYD1 PTHR19290:SF102 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED TRANSCRIPTION FACTOR ATOH8 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;sensory organ development#GO:0007423;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000002572.1|UniProtKB=W5M3R2 W5M3R2 PTHR47730:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 29 SMALL INTEGRAL MEMBRANE PROTEIN 29 LEPOC|Ensembl=ENSLOCG00000009823.1|UniProtKB=W5MUE9 W5MUE9 PTHR23327:SF6 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1 ISOFORM X1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004497.1|UniProtKB=W5MAG7 W5MAG7 PTHR15427:SF56 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER C1Q AND TNF-RELATED 9 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 lipid modification#GO:0030258;lipid oxidation#GO:0034440;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015453.1|UniProtKB=W5NEG0 W5NEG0 PTHR10106:SF38 CYTOCHROME B561-RELATED LYSOSOMAL MEMBRANE ASCORBATE-DEPENDENT FERRIREDUCTASE CYB561A3 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;catalytic activity#GO:0003824 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;carbohydrate homeostasis#GO:0033500;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000004210.1|UniProtKB=W5M9J7 W5M9J7 PTHR24347:SF386 SERINE/THREONINE-PROTEIN KINASE PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, SKELETAL MUSCLE_HEART ISOFORM protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;energy reserve metabolic process#GO:0006112;cell communication#GO:0007154;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;polysaccharide metabolic process#GO:0005976;response to stimulus#GO:0050896;carbohydrate metabolic process#GO:0005975;signaling#GO:0023052 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 LEPOC|Ensembl=ENSLOCG00000016502.1|UniProtKB=W5NIC5 W5NIC5 PTHR14554:SF1 GENE, 49416-RELATED 28S RRNA_RIBOSOME AND SORORIN MICRO-COFACTOR LEPOC|Ensembl=ENSLOCG00000007973.1|UniProtKB=W5MMS6 W5MMS6 PTHR42938:SF22 FORMATE DEHYDROGENASE 1 D-3-PHOSPHOGLYCERATE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxidoreductase#PC00176;dehydrogenase#PC00092 Serine glycine biosynthesis#P02776>Phosphoglycerate dehydrogenase#P03160 LEPOC|Ensembl=ENSLOCG00000002755.1|UniProtKB=W5M4D4 W5M4D4 PTHR23147:SF231 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING MOTIF PROTEIN 4.3 rhythmic process#GO:0048511;circadian rhythm#GO:0007623 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000012279.1|UniProtKB=W5N3A4 W5N3A4 PTHR45759:SF1 NUCLEOLAR GTP-BINDING PROTEIN 1 GTP-BINDING PROTEIN 4 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;GTPase activity#GO:0003924 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000016264.1|UniProtKB=W5NHF1 W5NHF1 PTHR14002:SF60 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZP DOMAIN-CONTAINING PROTEIN cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001375.1|UniProtKB=W5LZK4 W5LZK4 PTHR11481:SF132 IMMUNOGLOBULIN FC RECEPTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;immune system process#GO:0002376;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;regulation of biological process#GO:0050789 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009764.1|UniProtKB=W5MU70 W5MU70 PTHR46161:SF1 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE 5 transferase#PC00220;kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 LEPOC|Ensembl=ENSLOCG00000007303.1|UniProtKB=W5MKD5 W5MKD5 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023;binding#GO:0005488 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003355.1|UniProtKB=W5M6G5 W5M6G5 PTHR23257:SF878 SERINE-THREONINE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DDB_G0267514-RELATED protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Raf#P00893 LEPOC|Ensembl=ENSLOCG00000018255.1|UniProtKB=W5NNZ7 W5NNZ7 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000018193.1|UniProtKB=W5NNT5 W5NNT5 PTHR11767:SF20 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 15 transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000012021.1|UniProtKB=W5N2C5 W5N2C5 PTHR24246:SF52 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A1-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007663.1|UniProtKB=W5MLP2 W5MLP2 PTHR46257:SF1 TYROSINE-PROTEIN PHOSPHATASE CORKSCREW TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein binding#GO:0005515;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488 developmental process#GO:0032502;cellular process#GO:0009987;cell cycle#GO:0007049;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;cellular developmental process#GO:0048869 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>SHP2#P00647;Interferon-gamma signaling pathway#P00035>PTP#P00960;Angiogenesis#P00005>SHP2#P00181 LEPOC|Ensembl=ENSLOCG00000016977.1|UniProtKB=W5NK26 W5NK26 PTHR10625:SF46 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 2 histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338 SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000017950.1|UniProtKB=W5NN44 W5NN44 PTHR16008:SF6 F-BOX ONLY PROTEIN 4 SI:DKEY-12E7.1 cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000007814.1|UniProtKB=W5MM83 W5MM83 PTHR21512:SF5 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000015632.1|UniProtKB=W5NF35 W5NF35 PTHR21037:SF3 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL14M intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000013184.1|UniProtKB=W5N6I1 W5N6I1 PTHR19297:SF183 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER N-ACETYLLACTOSAMINIDE BETA-1,6-N-ACETYLGLUCOSAMINYL-TRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to transforming growth factor beta#GO:0071559 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000014969.1|UniProtKB=W5NCS6 W5NCS6 PTHR11073:SF37 CALRETICULIN AND CALNEXIN CALNEXIN small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;response to chemical#GO:0042221;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein folding#GO:0006457;catabolic process#GO:0009056;response to stimulus#GO:0050896 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012098.1|UniProtKB=W5N2M8 W5N2M8 PTHR12191:SF2 SOLUTE CARRIER FAMILY 39 METAL CATION SYMPORTER ZIP8 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;zinc ion transmembrane transporter activity#GO:0005385;bicarbonate transmembrane transporter activity#GO:0015106;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324 zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016513.1|UniProtKB=W5NID8 W5NID8 PTHR13417:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF146 E3 UBIQUITIN-PROTEIN LIGASE RNF146 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate derivative binding#GO:0097367;ubiquitin-protein transferase activity#GO:0004842;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004059.1|UniProtKB=W5M8Z2 W5M8Z2 PTHR23291:SF133 BAX INHIBITOR-RELATED BAX INHIBITOR 1 passive transmembrane transporter activity#GO:0022803;enzyme inhibitor activity#GO:0004857;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;molecular function inhibitor activity#GO:0140678;calcium ion transmembrane transporter activity#GO:0015085 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;response to topologically incorrect protein#GO:0035966;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to unfolded protein#GO:0006986;negative regulation of cell communication#GO:0010648;cellular response to unfolded protein#GO:0034620;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to topologically incorrect protein#GO:0035967;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to stress#GO:0033554;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 ion channel#PC00133;transporter#PC00227 Apoptosis signaling pathway#P00006>Bi1#P00277 LEPOC|Ensembl=ENSLOCG00000005877.1|UniProtKB=W5MFE4 W5MFE4 PTHR46120:SF1 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 2 methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000005610.1|UniProtKB=W5MEG1 W5MEG1 PTHR44324:SF6 WD40 REPEAT DOMAIN 95 WD REPEAT-CONTAINING PROTEIN ON Y CHROMOSOME LEPOC|Ensembl=ENSLOCG00000009951.1|UniProtKB=W5MUW0 W5MUW0 PTHR20900:SF0 NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000015064.1|UniProtKB=W5ND32 W5ND32 PTHR13403:SF6 SNURPORTIN1 RNUT1 PROTEIN RNA, U TRANSPORTER 1 SNURPORTIN-1 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013552.1|UniProtKB=W5N7U9 W5N7U9 PTHR43391:SF72 RETINOL DEHYDROGENASE-RELATED RETINOL DEHYDROGENASE 8 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000006940.1|UniProtKB=W5MJ39 W5MJ39 PTHR12143:SF45 PEPTIDE N-GLYCANASE PNGASE -RELATED PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 positive regulation of BMP signaling pathway#GO:0030513;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;regulation of BMP signaling pathway#GO:0030510;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;carbohydrate derivative catabolic process#GO:1901136;regulation of cell communication#GO:0010646;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 LEPOC|Ensembl=ENSLOCG00000003875.1|UniProtKB=W5M8B5 W5M8B5 PTHR46715:SF1 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell migration#GO:0016477;membrane organization#GO:0061024;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;membrane fusion#GO:0061025;organophosphate metabolic process#GO:0019637;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;leukocyte chemotaxis#GO:0030595;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;phagocytosis#GO:0006909;leukocyte migration#GO:0050900;lipid metabolic process#GO:0006629;transport#GO:0006810;lytic vacuole organization#GO:0080171;cell motility#GO:0048870;regulation of cellular process#GO:0050794;locomotion#GO:0040011;vesicle fusion#GO:0006906;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;localization#GO:0051179;cell chemotaxis#GO:0060326;vacuole organization#GO:0007033;organelle assembly#GO:0070925;chemotaxis#GO:0006935;pigmentation#GO:0043473;vesicle-mediated transport#GO:0016192;granulocyte migration#GO:0097530;neutrophil migration#GO:1990266;organelle fusion#GO:0048284;taxis#GO:0042330;glycerophospholipid metabolic process#GO:0006650;response to chemical#GO:0042221;cellular component assembly#GO:0022607;organelle membrane fusion#GO:0090174;cellular pigmentation#GO:0033059;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;lysosome organization#GO:0007040;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;phagolysosome assembly#GO:0001845;metabolic process#GO:0008152;neutrophil chemotaxis#GO:0030593;melanosome organization#GO:0032438;endocytosis#GO:0006897;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;regulation of reactive oxygen species metabolic process#GO:2000377 cytoplasm#GO:0005737;phagocytic vesicle#GO:0045335;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular organelle#GO:0043229 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000003573.1|UniProtKB=W5M790 W5M790 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000018030.1|UniProtKB=W5NNC2 W5NNC2 PTHR46890:SF1 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED SECRETED RXLR EFFECTOR PROTEIN 78-LIKE reverse transcriptase#PC00200;viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000012226.1|UniProtKB=W5N332 W5N332 PTHR19964:SF16 MULTIPLE PDZ DOMAIN PROTEIN SYNTAXIN-BINDING PROTEIN 4 SNARE binding#GO:0000149;binding#GO:0005488;syntaxin binding#GO:0019905;protein binding#GO:0005515 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;response to hormone#GO:0009725;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014527.1|UniProtKB=W5NB69 W5NB69 PTHR43986:SF1 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000000538.1|UniProtKB=W5LWU2 W5LWU2 PTHR23105:SF1 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN EL8 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000014619.1|UniProtKB=W5NBI2 W5NBI2 PTHR31395:SF18 SHISA SHISA FAMILY MEMBER 2A PRECURSOR scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010443.1|UniProtKB=W5MWP9 W5MWP9 PTHR10061:SF0 S-FORMYLGLUTATHIONE HYDROLASE S-FORMYLGLUTATHIONE HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000008083.1|UniProtKB=W5MN59 W5MN59 PTHR12801:SF78 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED INTERFERON-STIMULATED 20 KDA EXONUCLEASE-LIKE 2 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 exoribonuclease#PC00099;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011449.1|UniProtKB=W5N0B3 W5N0B3 PTHR11556:SF11 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 small molecule metabolic process#GO:0044281;carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;glucose metabolic process#GO:0006006;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 carbohydrate phosphatase#PC00066;hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000013582.1|UniProtKB=W5N7Z7 W5N7Z7 PTHR11630:SF44 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM2 single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;DNA repair#GO:0006281;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;MCM complex#GO:0042555;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000003940.1|UniProtKB=W5M8J6 W5M8J6 PTHR45655:SF15 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;lyase activity#GO:0016829;guanylate cyclase activity#GO:0004383 response to stimulus#GO:0050896;response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cytosol#GO:0005829 guanylate cyclase#PC00114;cyclase#PC00079 LEPOC|Ensembl=ENSLOCG00000005971.1|UniProtKB=W5MFQ7 W5MFQ7 PTHR16208:SF1 MICROTUBULE-ASSOCIATED PROTEIN/SYNTAPHILIN SYNTAPHILIN cellular process#GO:0009987;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;system development#GO:0048731;neurogenesis#GO:0022008 cytoplasmic microtubule#GO:0005881;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000017813.1|UniProtKB=W5NMQ8 W5NMQ8 PTHR15035:SF9 CORTICOLIBERIN/UROCORTIN CORTICOTROPIN-RELEASING HORMONE signaling receptor regulator activity#GO:0030545;neuropeptide receptor binding#GO:0071855;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;binding#GO:0005488;protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of hormone levels#GO:0010817;neuropeptide signaling pathway#GO:0007218;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of hormone secretion#GO:0046883;cell communication#GO:0007154;regulation of secretion#GO:0051046;positive regulation of signaling#GO:0023056;positive regulation of hormone secretion#GO:0046887;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;cellular process#GO:0009987;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of system process#GO:0044057 extracellular region#GO:0005576;cell body#GO:0044297;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 peptide hormone#PC00179;intercellular signal molecule#PC00207 Cortocotropin releasing factor receptor signaling pathway#P04380>CRF#P04454;Cortocotropin releasing factor receptor signaling pathway#P04380>ProCRF (Pro Corticotropin-Releasing Factor)#P04456 LEPOC|Ensembl=ENSLOCG00000018314.1|UniProtKB=W5NP56 W5NP56 PTHR24241:SF178 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014095.1|UniProtKB=W5N9Q4 W5N9Q4 PTHR10145:SF6 TRANSCRIPTION ELONGATION FACTOR SPT6 TRANSCRIPTION ELONGATION FACTOR SPT6 histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;nucleosome organization#GO:0034728;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018024.1|UniProtKB=W5NNB6 W5NNB6 PTHR10656:SF37 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 2 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;nucleotidyltransferase#PC00174 LEPOC|Ensembl=ENSLOCG00000009391.1|UniProtKB=W5MSU5 W5MSU5 PTHR24030:SF0 PROTEIN CMSS1 PROTEIN CMSS1 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001918.1|UniProtKB=W5M1G5 W5M1G5 PTHR12473:SF18 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4B hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005 LEPOC|Ensembl=ENSLOCG00000008026.1|UniProtKB=W5MMZ2 W5MMZ2 PTHR13593:SF158 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 LEPOC|Ensembl=ENSLOCG00000003418.1|UniProtKB=W5M6N5 W5M6N5 PTHR44133:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010629.1|UniProtKB=W5MXA9 W5MXA9 PTHR14134:SF2 E3 UBIQUITIN-PROTEIN LIGASE RAD18 E3 UBIQUITIN-PROTEIN LIGASE RAD18 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;DNA replication#GO:0006260;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008112.1|UniProtKB=W5MN97 W5MN97 PTHR15440:SF0 XRP2 PROTEIN PROTEIN XRP2 enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular process#GO:0009987;transport#GO:0006810;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cilium#GO:0005929;membrane-bounded organelle#GO:0043227 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000002939.1|UniProtKB=W5M510 W5M510 PTHR15268:SF16 THRAP3/BCLAF1 THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN 3 DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000011539.1|UniProtKB=W5N0L9 W5N0L9 PTHR22957:SF570 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 2A GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000002994.1|UniProtKB=W5M567 W5M567 PTHR12510:SF4 TROPONIN C-AKIN-1 PROTEIN GAMMA-GLUTAMYLAMINECYCLOTRANSFERASE cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000009660.1|UniProtKB=W5MTV3 W5MTV3 PTHR15923:SF0 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING RECEPTOR 2 animal organ development#GO:0048513;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;pancreas development#GO:0031016;developmental process#GO:0032502 membrane#GO:0016020;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007911.1|UniProtKB=W5MML0 W5MML0 PTHR15000:SF1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000002158.1|UniProtKB=W5M2C1 W5M2C1 PTHR18934:SF119 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE A isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017199.1|UniProtKB=W5NKV0 W5NKV0 PTHR14431:SF1 HCLS1-BINDING PROTEIN 3 HCLS1-BINDING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000004800.1|UniProtKB=W5MBK0 W5MBK0 PTHR13080:SF16 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE F(0) COMPLEX SUBUNIT F, MITOCHONDRIAL proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;small molecule metabolic process#GO:0044281;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;proton-transporting ATP synthase complex#GO:0045259;respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;catalytic complex#GO:1902494 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000012803.1|UniProtKB=W5N546 W5N546 PTHR18945:SF75 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-3 neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;acetylcholine receptor activity#GO:0015464;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 trans-synaptic signaling#GO:0099537;response to nitrogen compound#GO:1901698;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;metal ion transport#GO:0030001;modulation of chemical synaptic transmission#GO:0050804;membrane depolarization#GO:0051899;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;synaptic transmission, cholinergic#GO:0007271;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;neuromuscular synaptic transmission#GO:0007274;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;synaptic signaling#GO:0099536;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221 synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transporter complex#GO:1990351;cell junction#GO:0030054;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotine pharmacodynamics pathway#P06587>CHRNB3#P06612 LEPOC|Ensembl=ENSLOCG00000006082.1|UniProtKB=W5MG38 W5MG38 PTHR43127:SF2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000015010.1|UniProtKB=W5NCX5 W5NCX5 PTHR11134:SF11 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 microtubule-based transport#GO:0099111;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;cellular component organization#GO:0016043;establishment of organelle localization#GO:0051656;Golgi vesicle transport#GO:0048193;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;lysosome organization#GO:0007040;organelle organization#GO:0006996;synaptic vesicle transport#GO:0048489;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;axonal transport#GO:0098930;organelle localization#GO:0051640;vacuole organization#GO:0007033;anterograde axonal transport#GO:0008089;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;microtubule-based movement#GO:0007018;vacuolar transport#GO:0007034;transport#GO:0006810;lytic vacuole organization#GO:0080171;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;vesicle cytoskeletal trafficking#GO:0099518;anterograde synaptic vesicle transport#GO:0048490;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;vesicle localization#GO:0051648;axo-dendritic transport#GO:0008088;cytoskeleton-dependent intracellular transport#GO:0030705 membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005322.1|UniProtKB=W5MDF8 W5MDF8 PTHR11850:SF53 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN PKNOX2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006632.1|UniProtKB=W5MI00 W5MI00 PTHR15276:SF0 H4 D10S170 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000007972.1|UniProtKB=W5MMS9 W5MMS9 PTHR43447:SF61 ALPHA-AMYLASE ALPHA-AMYLASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 amylase#PC00048 LEPOC|Ensembl=ENSLOCG00000009930.1|UniProtKB=W5MUU4 W5MUU4 PTHR23503:SF35 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 9 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 transport#GO:0006810;carbohydrate transport#GO:0008643;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009650.1|UniProtKB=W5MTT8 W5MTT8 PTHR13295:SF4 GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT GLUTAMATE--CYSTEINE LIGASE REGULATORY SUBUNIT protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899 biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006679.1|UniProtKB=W5MIA6 W5MIA6 PTHR24115:SF328 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1B cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;hydrolase activity#GO:0016787;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017 localization#GO:0051179;cellular localization#GO:0051641;axonal transport#GO:0098930;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;retrograde axonal transport#GO:0008090;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;cytosolic transport#GO:0016482;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;microtubule-based process#GO:0007017;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;axo-dendritic transport#GO:0008088;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;axon#GO:0030424;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002905.1|UniProtKB=W5M4V4 W5M4V4 PTHR14511:SF9 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G PROTEIN-COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER B enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677;kinase binding#GO:0019900;binding#GO:0005488;kinase activator activity#GO:0019209;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;signaling receptor complex#GO:0043235;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;vesicle#GO:0031982 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001226.1|UniProtKB=W5LZ32 W5LZ32 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 antigen binding#GO:0003823;binding#GO:0005488 leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252;response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000018047.1|UniProtKB=W5NND9 W5NND9 PTHR24232:SF3 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 6 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011269.1|UniProtKB=W5MZN9 W5MZN9 PTHR12733:SF3 MITOCHONDRIAL ATP SYNTHASE B CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT B, MITOCHONDRIAL proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324 organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987 protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;transporter complex#GO:1990351;organelle membrane#GO:0031090;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 primary active transporter#PC00068;ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000017076.1|UniProtKB=W5NKG0 W5NKG0 PTHR24023:SF918 COLLAGEN ALPHA COLLAGEN ALPHA-1(IX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;supramolecular complex#GO:0099080;interstitial matrix#GO:0005614;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000009872.1|UniProtKB=W5MUK8 W5MUK8 PTHR23409:SF19 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 B biosynthetic process#GO:0009058;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 reductase#PC00198;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909 LEPOC|Ensembl=ENSLOCG00000005308.1|UniProtKB=W5MDD7 W5MDD7 PTHR31622:SF1 TRANSMEMBRANE PROTEIN 218 TRANSMEMBRANE PROTEIN 218 LEPOC|Ensembl=ENSLOCG00000001925.1|UniProtKB=W5M1I1 W5M1I1 PTHR11056:SF0 HOMOGENTISATE 1,2-DIOXYGENASE HOMOGENTISATE 1,2-DIOXYGENASE oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000011183.1|UniProtKB=W5MZC5 W5MZC5 PTHR12878:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 2 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013280.1|UniProtKB=W5N6V3 W5N6V3 PTHR12471:SF3 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1-LIKE PROTEIN chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;biological regulation#GO:0065007;homeostatic process#GO:0042592 ATPase dependent transmembrane transport complex#GO:0098533;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane#GO:0016020;membrane protein complex#GO:0098796 ATP synthase#PC00002;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000016372.1|UniProtKB=W5NHV6 W5NHV6 PTHR23281:SF13 MERLIN/MOESIN/EZRIN/RADIXIN EZRIN binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 regulation of anatomical structure morphogenesis#GO:0022603;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein localization#GO:0032880;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of developmental process#GO:0050793 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;filopodium#GO:0030175;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;membraneless organelle#GO:0043228;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical part of cell#GO:0045177 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000003665.1|UniProtKB=W5M7K5 W5M7K5 PTHR13281:SF0 TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000010932.1|UniProtKB=W5MYG9 W5MYG9 PTHR11799:SF12 PARAOXONASE PARAOXONASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017004.1|UniProtKB=W5NK58 W5NK58 PTHR28549:SF1 GLYCOPROTEIN INTEGRAL MEMBRANE PROTEIN 1 GLYCOPROTEIN INTEGRAL MEMBRANE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000005084.1|UniProtKB=W5MCN5 W5MCN5 PTHR21502:SF5 ZINC FINGER PROTEIN DZIP1 CILIUM ASSEMBLY PROTEIN DZIP1 binding#GO:0005488;molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008338.1|UniProtKB=W5MP16 W5MP16 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000012459.1|UniProtKB=W5N3Y0 W5N3Y0 PTHR31395:SF4 SHISA PROTEIN SHISA-3 HOMOLOG scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015994.1|UniProtKB=W5NGE1 W5NGE1 PTHR14618:SF4 HOMEODOX-CONTAINING PROTEIN 1 HMBOX1 HOMEOBOX-CONTAINING PROTEIN 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000003091.1|UniProtKB=W5M5I5 W5M5I5 PTHR22603:SF68 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000000672.1|UniProtKB=W5LX84 W5LX84 PTHR22803:SF180 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN-RELATED membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000004428.1|UniProtKB=W5MA80 W5MA80 PTHR13962:SF17 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N4 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000011752.1|UniProtKB=W5N1F1 W5N1F1 PTHR43243:SF19 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER C-TERMINAL DOMAIN-CONTAINING PROTEIN amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;amino acid transport#GO:0006865 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000013485.1|UniProtKB=W5N7M5 W5N7M5 PTHR10013:SF7 GENERAL VESICULAR TRANSPORT FACTOR P115 GENERAL VESICULAR TRANSPORT FACTOR P115 Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component organization#GO:0016043;membrane fusion#GO:0061025;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;vesicle#GO:0031982;Golgi stack#GO:0005795;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;cytoplasm#GO:0005737;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008520.1|UniProtKB=W5MPQ9 W5MPQ9 PTHR47535:SF2 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G NESPRIN-3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 nuclear migration#GO:0007097;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of organelle localization#GO:0051656;transport#GO:0006810;organelle localization#GO:0051640;intracellular transport#GO:0046907;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 nuclear protein-containing complex#GO:0140513;nuclear membrane#GO:0031965;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;membrane#GO:0016020;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967 LEPOC|Ensembl=ENSLOCG00000014198.1|UniProtKB=W5NA31 W5NA31 PTHR16133:SF5 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED ZINC TRANSPORTER ZIP9 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000000355.1|UniProtKB=W5LW81 W5LW81 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000020992.1|UniProtKB=Q8HQM5 Q8HQM5 PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003039.1|UniProtKB=W5M5B4 W5M5B4 PTHR10394:SF3 40S RIBOSOMAL PROTEIN S8 SMALL RIBOSOMAL SUBUNIT PROTEIN ES8 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000006667.1|UniProtKB=W5MI77 W5MI77 PTHR11216:SF68 EH DOMAIN INTERSECTIN-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular localization#GO:0051641;endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;synaptic vesicle endocytosis#GO:0048488;endosomal transport#GO:0016197;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;intracellular transport#GO:0046907;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018230.1|UniProtKB=W5NNX2 W5NNX2 PTHR24248:SF123 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948 LEPOC|Ensembl=ENSLOCG00000008764.1|UniProtKB=W5MQL0 W5MQL0 PTHR11006:SF60 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 9 histone modifying activity#GO:0140993;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015736.1|UniProtKB=W5NFG0 W5NFG0 PTHR10331:SF28 T COMPLEX PROTEIN 10 CENTROMERE PROTEIN J C-TERMINAL DOMAIN-CONTAINING PROTEIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 cell cycle#GO:0007049;cilium assembly#GO:0060271;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell projection organization#GO:0030030;organelle assembly#GO:0070925;centriole replication#GO:0007099;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000013197.1|UniProtKB=W5N6L7 W5N6L7 PTHR24040:SF8 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN FIBRILLIN 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000010512.1|UniProtKB=W5MWX2 W5MWX2 PTHR14239:SF5 DUDULIN-RELATED METALLOREDUCTASE STEAP4 oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491;ferric-chelate reductase activity#GO:0000293;catalytic activity#GO:0003824 transport#GO:0006810;transition metal ion transport#GO:0000041;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000015199.1|UniProtKB=W5NDJ4 W5NDJ4 PTHR45899:SF5 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;phosphatidylinositol phosphate binding#GO:1901981;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000009711.1|UniProtKB=W5MU04 W5MU04 PTHR11636:SF47 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 Gonadotropin-releasing hormone receptor pathway#P06664>OCT-1#P06720 LEPOC|Ensembl=ENSLOCG00000000988.1|UniProtKB=W5LYA4 W5LYA4 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010486.1|UniProtKB=W5MWU3 W5MWU3 PTHR16768:SF3 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A ACTIN-ASSOCIATED PROTEIN FAM107A actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;actin filament bundle organization#GO:0061572;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;actin filament bundle assembly#GO:0051017;regulation of biological process#GO:0050789;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;actin filament polymerization#GO:0030041;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 intracellular membraneless organelle#GO:0043232;neuron projection#GO:0043005;actomyosin#GO:0042641;cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;stress fiber#GO:0001725;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;actin filament bundle#GO:0032432;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012240.1|UniProtKB=W5N352 W5N352 PTHR20854:SF44 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;glycerophospholipid biosynthetic process#GO:0046474;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000003777.1|UniProtKB=W5M811 W5M811 PTHR24023:SF1113 COLLAGEN ALPHA COLLAGEN ALPHA-1(IX) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000013495.1|UniProtKB=W5N7P2 W5N7P2 PTHR10372:SF9 PLAKOPHILLIN-RELATED CATENIN DELTA-2 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 dendrite morphogenesis#GO:0048813;dendritic spine development#GO:0060996;postsynapse organization#GO:0099173;dendritic spine morphogenesis#GO:0060997;cell junction organization#GO:0034330;synapse organization#GO:0050808;system development#GO:0048731;anatomical structure development#GO:0048856;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;neuron projection organization#GO:0106027;cell morphogenesis#GO:0000902;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;dendrite development#GO:0016358;dendritic spine organization#GO:0097061;cellular process#GO:0009987;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;postsynaptic density#GO:0014069;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell-cell junction#GO:0005911;nucleus#GO:0005634;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell junction#GO:0030054;adherens junction#GO:0005912 intermediate filament binding protein#PC00130;intermediate filament#PC00129;cytoskeletal protein#PC00085 Cadherin signaling pathway#P00012>P120#P00473 LEPOC|Ensembl=ENSLOCG00000016241.1|UniProtKB=W5NHC5 W5NHC5 PTHR10199:SF120 THROMBOSPONDIN THROMBOSPONDIN 2B-RELATED extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000002917.1|UniProtKB=W5M4X2 W5M4X2 PTHR42808:SF3 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000011315.1|UniProtKB=W5MZU6 W5MZU6 PTHR14208:SF7 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN EIF5-MIMIC PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000007939.1|UniProtKB=W5MMN4 W5MMN4 PTHR19282:SF257 TETRASPANIN TETRASPANIN-7 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000954.1|UniProtKB=W5LY62 W5LY62 PTHR23324:SF39 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 5 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000017397.1|UniProtKB=W5NLJ3 W5NLJ3 PTHR24232:SF44 G-PROTEIN COUPLED RECEPTOR URACIL NUCLEOTIDE_CYSTEINYL LEUKOTRIENE RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013452.1|UniProtKB=W5N7I6 W5N7I6 PTHR11827:SF98 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 9 chloride transmembrane transporter activity#GO:0015108;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000010663.1|UniProtKB=W5MXF4 W5MXF4 PTHR43795:SF51 BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED AMINOTRANSFERASE CLASS I_CLASSII LARGE DOMAIN-CONTAINING PROTEIN lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000005143.1|UniProtKB=W5MCT5 W5MCT5 PTHR46575:SF1 AMYLOID PROTEIN-BINDING PROTEIN 2 AMYLOID PROTEIN-BINDING PROTEIN 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 LEPOC|Ensembl=ENSLOCG00000015528.1|UniProtKB=W5NER5 W5NER5 PTHR11915:SF226 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cellular process#GO:0009987;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;organelle organization#GO:0006996;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179 actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000001245.1|UniProtKB=W5LZ53 W5LZ53 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune effector process#GO:0002252;immune system process#GO:0002376;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000135.1|UniProtKB=W5LVJ1 W5LVJ1 PTHR44411:SF1 THO COMPLEX SUBUNIT 6 HOMOLOG THO COMPLEX SUBUNIT 6 nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705 nucleus#GO:0005634;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transcription export complex#GO:0000346;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000013489.1|UniProtKB=W5N7N2 W5N7N2 PTHR11254:SF282 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE NEDD4 molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;transporter regulator activity#GO:0141108;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;catalytic activity#GO:0003824;transferase activity#GO:0016740 synapse organization#GO:0050808;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;regulation of synapse structure or activity#GO:0050803;localization#GO:0051179;system development#GO:0048731;regulation of dendrite morphogenesis#GO:0048814;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;catabolic process#GO:0009056;regulation of developmental process#GO:0050793;regulation of cell projection organization#GO:0031344;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;regulation of plasma membrane bounded cell projection organization#GO:0120035;neurogenesis#GO:0022008;ubiquitin-dependent protein catabolic process#GO:0006511;receptor-mediated endocytosis#GO:0006898;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;modification-dependent macromolecule catabolic process#GO:0043632;regulation of synapse organization#GO:0050807;generation of neurons#GO:0048699;protein catabolic process#GO:0030163;regulation of biological quality#GO:0065008;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;endocytosis#GO:0006897;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell development#GO:0048468;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;neuron differentiation#GO:0030182;import into cell#GO:0098657;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuromuscular junction development#GO:0007528;neuron projection development#GO:0031175;receptor internalization#GO:0031623;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000017711.1|UniProtKB=W5NMF7 W5NMF7 PTHR15344:SF20 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 3-LIKE small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 regulation of anatomical structure size#GO:0090066;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;intracellular signaling cassette#GO:0141124;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;Rho protein signal transduction#GO:0007266;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;small GTPase-mediated signal transduction#GO:0007264;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;positive regulation of cell projection organization#GO:0031346;regulation of cell projection assembly#GO:0060491;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of supramolecular fiber organization#GO:1902903;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271 cell periphery#GO:0071944;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008566.1|UniProtKB=W5MPX5 W5MPX5 PTHR15717:SF2 PROTEIN KIAA0494 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 14 LEPOC|Ensembl=ENSLOCG00000003197.1|UniProtKB=W5M5X4 W5M5X4 PTHR24306:SF4 FAMILY NOT NAMED PROSTACYCLIN SYNTHASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;unsaturated fatty acid biosynthetic process#GO:0006636;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;icosanoid biosynthetic process#GO:0046456;lipid biosynthetic process#GO:0008610;icosanoid metabolic process#GO:0006690;prostaglandin metabolic process#GO:0006693;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281 LEPOC|Ensembl=ENSLOCG00000006246.1|UniProtKB=W5MGP0 W5MGP0 PTHR47965:SF69 ASPARTYL PROTEASE-RELATED BETA-SECRETASE 1 aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;membrane protein proteolysis#GO:0033619;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;membrane protein ectodomain proteolysis#GO:0006509 Golgi apparatus#GO:0005794;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>Pro-BACE-1#P00081;Alzheimer disease-presenilin pathway#P00004>Pro-BACE-1#P00162;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1#P00101;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1 pro-domain#P00094;Alzheimer disease-presenilin pathway#P00004>BACE-1#P00172;Alzheimer disease-presenilin pathway#P00004>BACE-1 pro-domain#P00178 LEPOC|Ensembl=ENSLOCG00000009013.1|UniProtKB=W5MRH8 W5MRH8 PTHR23114:SF17 M7GPPPN-MRNA HYDROLASE M7GPPPN-MRNA HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 LEPOC|Ensembl=ENSLOCG00000002648.1|UniProtKB=W5M3Z9 W5M3Z9 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011682.1|UniProtKB=W5N147 W5N147 PTHR24416:SF651 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TYRO3 transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;cell motility#GO:0048870;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;response to stimulus#GO:0050896;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;localization#GO:0051179;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell migration#GO:0016477;transport#GO:0006810;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;phagocytosis#GO:0006909;establishment of localization#GO:0051234;import into cell#GO:0098657;multicellular organism development#GO:0007275 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013094.1|UniProtKB=W5N671 W5N671 PTHR21575:SF12 PROTEIN HID1 PROTEIN HID1 developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;anatomical structure maturation#GO:0071695;Golgi organization#GO:0007030;developmental maturation#GO:0021700;endomembrane system organization#GO:0010256 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;Golgi cisterna#GO:0031985;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;Golgi stack#GO:0005795 LEPOC|Ensembl=ENSLOCG00000010390.1|UniProtKB=W5MWH9 W5MWH9 PTHR24083:SF44 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP F MEMBER 6 sequence-specific double-stranded DNA binding#GO:1990837;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000010594.1|UniProtKB=W5MX60 W5MX60 PTHR10250:SF26 MICROSOMAL GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL glutathione transferase activity#GO:0004364;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity#GO:0016491 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016324.1|UniProtKB=W5NHP4 W5NHP4 PTHR15657:SF1 THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000013234.1|UniProtKB=W5N6P0 W5N6P0 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED binding#GO:0005488;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004989.1|UniProtKB=W5MC99 W5MC99 PTHR34759:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 48 PROTEIN SPMIP7 spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproductive process#GO:0022414 LEPOC|Ensembl=ENSLOCG00000014533.1|UniProtKB=W5NB79 W5NB79 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN DMBT1 cargo receptor activity#GO:0038024 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000009984.1|UniProtKB=W5MV05 W5MV05 PTHR24353:SF82 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;renal system process#GO:0003014;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;system process#GO:0003008;renal absorption#GO:0070293 protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Nicotine pharmacodynamics pathway#P06587>PRKACA#P06588;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;GABA-B receptor II signaling#P05731>PKA#P05752;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Endothelin signaling pathway#P00019>PKA#P00570;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-c#P00707;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Enkephalin release#P05913>PKA#P05972;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050 LEPOC|Ensembl=ENSLOCG00000010434.1|UniProtKB=W5MWQ7 W5MWQ7 PTHR11566:SF54 DYNAMIN DYNAMIN-3 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;microtubule binding#GO:0008017;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;ribonucleoside triphosphate phosphatase activity#GO:0017111 establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;synaptic vesicle endocytosis#GO:0048488;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;synaptic vesicle recycling#GO:0036465;membrane organization#GO:0061024;establishment of vesicle localization#GO:0051650;organelle organization#GO:0006996;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;synaptic vesicle cycle#GO:0099504;transport#GO:0006810 organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017082.1|UniProtKB=W5NKF2 W5NKF2 PTHR24229:SF88 NEUROPEPTIDES RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 2 peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001523.1|UniProtKB=W5M027 W5M027 PTHR24120:SF3 GH07239P ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 29 LEPOC|Ensembl=ENSLOCG00000000238.1|UniProtKB=W5LVV5 W5LVV5 PTHR24232:SF85 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014114.1|UniProtKB=W5N9T0 W5N9T0 PTHR15960:SF3 LD44032P UBIQUITIN-ASSOCIATED PROTEIN 1-LIKE binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 catabolic process#GO:0009056;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle membrane#GO:0012506;ESCRT I complex#GO:0000813;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000015751.1|UniProtKB=W5NFI1 W5NFI1 PTHR23093:SF16 SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 FAM194 C-TERMINAL DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000004675.1|UniProtKB=W5MB40 W5MB40 PTHR48032:SF10 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 RNA-BINDING PROTEIN MUSASHI HOMOLOG 2 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006698.1|UniProtKB=W5MI79 W5MI79 PTHR14132:SF15 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 6-RELATED channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015678.1|UniProtKB=W5NF89 W5NF89 AARS PTHR11777:SF8 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;ligase activity#GO:0016874;deacylase activity#GO:0160215;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000005574.1|UniProtKB=W5MEC3 W5MEC3 PTHR45832:SF21 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE Ras Pathway#P04393>PAK#P04553;Angiogenesis#P00005>PAK#P00249;T cell activation#P00053>PAK#P01319;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517 LEPOC|Ensembl=ENSLOCG00000002856.1|UniProtKB=W5M4Q0 W5M4Q0 PTHR16322:SF0 PHOSPHOPROTEIN ASSOCIATED WITH GLYCOSPHINGOLIPID-ENRICHED MICRODOMAINS 1 PHOSPHOPROTEIN ASSOCIATED WITH GLYCOSPHINGOLIPID-ENRICHED MICRODOMAINS 1 regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of leukocyte cell-cell adhesion#GO:1903038;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of T cell activation#GO:0050868;regulation of T cell activation#GO:0050863;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;negative regulation of cell-cell adhesion#GO:0022408;regulation of multicellular organismal process#GO:0051239;negative regulation of lymphocyte activation#GO:0051250;negative regulation of leukocyte activation#GO:0002695;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of cell activation#GO:0050866;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane raft#GO:0045121;membrane#GO:0016020;cell periphery#GO:0071944;membrane microdomain#GO:0098857 LEPOC|Ensembl=ENSLOCG00000004576.1|UniProtKB=W5MAR9 W5MAR9 PTHR45682:SF3 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 13A catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000007332.1|UniProtKB=W5MKG9 W5MKG9 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED reverse transcriptase#PC00200;viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000007846.1|UniProtKB=W5MMB7 W5MMB7 PTHR11256:SF46 BCL-2 RELATED INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;mitochondrial fusion#GO:0008053;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;apoptotic signaling pathway#GO:0097190;positive regulation of neuron apoptotic process#GO:0043525;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;regulation of neuron apoptotic process#GO:0043523;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 CCKR signaling map#P06959>MCL1#G07275;CCKR signaling map#P06959>MCL1#G06982;Apoptosis signaling pathway#P00006>Mcl1#P00308 LEPOC|Ensembl=ENSLOCG00000014923.1|UniProtKB=W5NCL7 W5NCL7 PTHR12409:SF0 PREFOLDIN SUBUNIT 3 PREFOLDIN SUBUNIT 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein folding#GO:0006457;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;protein metabolic process#GO:0019538;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000016670.1|UniProtKB=W5NIY4 W5NIY4 PTHR11486:SF150 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104 positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000009386.1|UniProtKB=W5MSW3 W5MSW3 PTHR45994:SF2 FI21225P1 PROTEIN UNC-45 HOMOLOG B protein binding#GO:0005515;Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072;binding#GO:0005488 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000000844.1|UniProtKB=W5LXT3 W5LXT3 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000012807.1|UniProtKB=W5N555 W5N555 PTHR18952:SF287 CARBONIC ANHYDRASE CARBONIC ANHYDRASE catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000007058.1|UniProtKB=W5MJI4 W5MJI4 PTHR24246:SF47 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A2A transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic transmission, dopaminergic#GO:0001963;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell surface receptor signaling pathway#GO:0007166;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;G protein-coupled adenosine receptor signaling pathway#GO:0001973 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000012727.1|UniProtKB=W5N4W4 W5N4W4 PTHR22730:SF4 PROMININ PROM PROTEIN PROMININ-1-A-LIKE cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cellular process#GO:0009987 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000009964.1|UniProtKB=W5MUX5 W5MUX5 PTHR10210:SF123 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000009855.1|UniProtKB=W5MUI7 W5MUI7 PTHR15082:SF2 NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3 electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012644.1|UniProtKB=W5N4L5 W5N4L5 PTHR22957:SF168 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001773.1|UniProtKB=W5M0Z1 W5M0Z1 PTHR23423:SF80 ORGANIC SOLUTE TRANSPORTER-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT ALPHA transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015360.1|UniProtKB=W5NE44 W5NE44 PTHR13544:SF6 SELENOPROTEIN T SELENOPROTEIN T2 antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000003403.1|UniProtKB=W5M6M1 W5M6M1 PTHR23034:SF2 GLUTAMATE-RICH PROTEIN 3 GLUTAMATE-RICH PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000013328.1|UniProtKB=W5N723 W5N723 PTHR46006:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000015195.1|UniProtKB=W5NDJ0 W5NDJ0 PTHR11711:SF41 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 1 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 LEPOC|Ensembl=ENSLOCG00000013748.1|UniProtKB=W5N8J4 W5N8J4 PTHR28554:SF1 39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML45 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015238.1|UniProtKB=W5NDP2 W5NDP2 PTHR13112:SF1 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN REGULATOR OF NONSENSE TRANSCRIPTS 3B mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of protein metabolic process#GO:0051247;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;positive regulation of macromolecule metabolic process#GO:0010604;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008288.1|UniProtKB=W5MNV6 W5MNV6 PTHR12369:SF40 CHONDROITIN SYNTHASE CHONDROITIN SULFATE SYNTHASE 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000007808.1|UniProtKB=W5MM72 W5MM72 PTHR23159:SF47 CENTROSOMAL PROTEIN 2 ROOTLETIN-LIKE COILED-COIL DOMAIN-CONTAINING PROTEIN chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000010918.1|UniProtKB=W5MYF8 W5MYF8 PTHR24223:SF405 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 3 transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;xenobiotic transmembrane transporter activity#GO:0042910;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000018161.1|UniProtKB=W5NNQ3 W5NNQ3 PTHR22750:SF6 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 4 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;regulation of multicellular organismal process#GO:0051239;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015508.1|UniProtKB=W5NEM4 W5NEM4 PTHR11213:SF5 GLUCAGON-FAMILY NEUROPEPTIDE VIP PEPTIDES signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;neuropeptide hormone activity#GO:0005184;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;binding#GO:0005488;protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 regulation of cell communication#GO:0010646;export from cell#GO:0140352;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;secretion by cell#GO:0032940;organic hydroxy compound transport#GO:0015850;regulation of protein localization#GO:0032880;secretion#GO:0046903;positive regulation of signaling#GO:0023056;localization#GO:0051179;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;establishment of localization#GO:0051234;regulation of response to stimulus#GO:0048583;transport#GO:0006810;positive regulation of intracellular signal transduction#GO:1902533 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuron projection#GO:0043005 neuropeptide#PC00162 LEPOC|Ensembl=ENSLOCG00000004009.1|UniProtKB=W5M8T2 W5M8T2 PTHR11461:SF48 SERINE PROTEASE INHIBITOR, SERPIN GLIA-DERIVED NEXIN peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000012764.1|UniProtKB=W5N4Z5 W5N4Z5 PTHR48097:SF9 L-THREONINE ALDOLASE-RELATED L-THREONINE ALDOLASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 aldolase#PC00044;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000009586.1|UniProtKB=W5MTK5 W5MTK5 PTHR14187:SF46 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12A LEPOC|Ensembl=ENSLOCG00000002073.1|UniProtKB=W5M227 W5M227 PTHR23116:SF36 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED HARMONIN cell projection organization#GO:0030030;sensory perception of sound#GO:0007605;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;inner ear receptor cell stereocilium organization#GO:0060122;anatomical structure development#GO:0048856;neuron development#GO:0048666;ear development#GO:0043583;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;nervous system process#GO:0050877;sensory perception of mechanical stimulus#GO:0050954;generation of neurons#GO:0048699;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;inner ear development#GO:0048839;neuron projection development#GO:0031175;cellular process#GO:0009987;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;system process#GO:0003008;sensory organ development#GO:0007423;developmental process#GO:0032502;neuron differentiation#GO:0030182 cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;photoreceptor inner segment#GO:0001917;cilium#GO:0005929;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;membraneless organelle#GO:0043228;stereocilium#GO:0032420;cytoskeleton#GO:0005856;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000006625.1|UniProtKB=W5MHZ0 W5MHZ0 PTHR36292:SF1 UPF0575 PROTEIN C19ORF67 UPF0575 PROTEIN C19ORF67 LEPOC|Ensembl=ENSLOCG00000003547.1|UniProtKB=W5M735 W5M735 PTHR24023:SF914 COLLAGEN ALPHA OTOLIN-1 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000009623.1|UniProtKB=W5MTP5 W5MTP5 PTHR23227:SF87 BUCENTAUR RELATED PROTEIN CFDP2 LEPOC|Ensembl=ENSLOCG00000001950.1|UniProtKB=W5M1K3 W5M1K3 PTHR28586:SF1 PROTEIN PAXX PROTEIN PAXX DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;nucleus#GO:0005634;DNA repair complex#GO:1990391;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nonhomologous end joining complex#GO:0070419;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000012975.1|UniProtKB=W5N5S0 W5N5S0 PTHR12619:SF20 RFX TRANSCRIPTION FACTOR FAMILY TRANSCRIPTION FACTOR RFX3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000004420.1|UniProtKB=W5MAB5 W5MAB5 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER PANCREATIC ELASTASE serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002852.1|UniProtKB=W5M4P8 W5M4P8 PTHR15092:SF37 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 TARGET OF EGR1 PROTEIN 1 3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA binding#GO:0003723;snRNA binding#GO:0017069;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098 snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000013995.1|UniProtKB=W5N9E9 W5N9E9 PTHR24115:SF600 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF23 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515 organelle assembly#GO:0070925;nuclear division#GO:0000280;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;mitotic cell cycle#GO:0000278;microtubule-based movement#GO:0007018;mitotic spindle organization#GO:0007052;chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;cellular component assembly#GO:0022607 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000015165.1|UniProtKB=W5NDF4 W5NDF4 PTHR12771:SF2 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 3 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987 cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;cilium#GO:0005929;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014347.1|UniProtKB=W5NAK9 W5NAK9 PTHR47977:SF81 RAS-RELATED PROTEIN RAB RAS AND EF-HAND DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000007956.1|UniProtKB=W5MMQ3 W5MMQ3 PTHR24412:SF304 KELCH PROTEIN KELCH-LIKE PROTEIN 23 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002563.1|UniProtKB=W5M3V0 W5M3V0 PTHR11849:SF161 ETS FRIEND LEUKEMIA INTEGRATION 1 TRANSCRIPTION FACTOR DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000017726.1|UniProtKB=W5NMH1 W5NMH1 PTHR14679:SF1 GEM-ASSOCIATED PROTEIN 7 GEM-ASSOCIATED PROTEIN 7 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396 Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000012233.1|UniProtKB=W5N337 W5N337 PTHR11988:SF28 THYROTROPH EMBRYONIC FACTOR RELATED HEPATIC LEUKEMIA FACTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000011050.1|UniProtKB=W5MYV4 W5MYV4 PTHR31878:SF1 CHEMOKINE-LIKE PROTEIN TAFA-5-RELATED CHEMOKINE-LIKE PROTEIN TAFA-5 ISOFORM X1 cytokine#PC00083;chemokine#PC00074 LEPOC|Ensembl=ENSLOCG00000012541.1|UniProtKB=W5N492 W5N492 PTHR46071:SF3 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 2 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004727.1|UniProtKB=W5MBA9 W5MBA9 PTHR22804:SF24 AGGRECAN/VERSICAN PROTEOGLYCAN NEUROCAN CORE PROTEIN multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399;anatomical structure development#GO:0048856;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 extracellular region#GO:0005576;cell junction#GO:0030054;membrane#GO:0016020;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000009157.1|UniProtKB=W5MS02 W5MS02 PTHR11245:SF2 STANNIOCALCIN STANNIOCALCIN-2 chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;calcium ion homeostasis#GO:0055074;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000008811.1|UniProtKB=W5MQR2 W5MQR2 PTHR45973:SF12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN REGULATORY COMPLEX SUBUNIT 3 cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000015351.1|UniProtKB=W5NE32 W5NE32 PTHR22730:SF6 PROMININ PROM PROTEIN PROMININ-2 cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;vesicle#GO:0031982;actin-based cell projection#GO:0098858;microvillus#GO:0005902;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000007830.1|UniProtKB=W5MMA1 W5MMA1 PTHR47135:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000016610.1|UniProtKB=W5NIR1 W5NIR1 PTHR12673:SF98 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 4 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;filopodium assembly#GO:0046847;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000008455.1|UniProtKB=W5MPH8 W5MPH8 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;cell communication#GO:0007154;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;immune system process#GO:0002376 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012557.1|UniProtKB=W5N4A3 W5N4A3 PTHR11778:SF7 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, CYTOPLASMIC binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;tRNA binding#GO:0000049;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000004205.1|UniProtKB=W5M9G5 W5M9G5 PTHR10938:SF9 TRANSLATION INITIATION FACTOR IF-3 TRANSLATION INITIATION FACTOR IF-3, MITOCHONDRIAL translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000001126.1|UniProtKB=W5LYT1 W5LYT1 PTHR12027:SF105 WNT RELATED PROTEIN WNT-4A molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125 multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;system development#GO:0048731;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 LEPOC|Ensembl=ENSLOCG00000012388.1|UniProtKB=W5N3Q3 W5N3Q3 PTHR15711:SF10 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 1 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization or biogenesis#GO:0071840;regulation of synaptic plasticity#GO:0048167;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;organelle organization#GO:0006996;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;regulation of synapse organization#GO:0050807;regulation of signaling#GO:0023051;actin filament-based process#GO:0030029;regulation of dendritic spine morphogenesis#GO:0061001;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;modulation of chemical synaptic transmission#GO:0050804;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of postsynapse organization#GO:0099175;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 GTPase-activating protein#PC00257;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000001547.1|UniProtKB=W5M065 W5M065 PTHR12509:SF9 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERM FLAGELLAR PROTEIN 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000017998.1|UniProtKB=W5NN90 W5NN90 PTHR24034:SF204 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-LIKE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000007155.1|UniProtKB=W5MJV5 W5MJV5 PTHR22802:SF473 C-TYPE LECTIN SUPERFAMILY MEMBER CD209F ANTIGEN-RELATED binding#GO:0005488;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015183.1|UniProtKB=W5NDH2 W5NDH2 PTHR21324:SF11 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 1 regulation of catabolic process#GO:0009894;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of autophagy#GO:0010506 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;lysosome#GO:0005764 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005540.1|UniProtKB=W5ME91 W5ME91 PTHR14149:SF12 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP2 protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;cytoskeletal protein binding#GO:0008092;calmodulin binding#GO:0005516;enzyme activator activity#GO:0008047 actin filament organization#GO:0007015;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actomyosin contractile ring assembly#GO:0000915;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;supramolecular fiber organization#GO:0097435;cortical actin cytoskeleton organization#GO:0030866;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic cytokinetic process#GO:1902410;cell cycle process#GO:0022402;cell division#GO:0051301;cell cycle#GO:0007049;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036 cell cortex#GO:0005938;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000015711.1|UniProtKB=W5NFD3 W5NFD3 PTHR11839:SF1 UDP/ADP-SUGAR PYROPHOSPHATASE ADP-SUGAR PYROPHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462 small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 pyrophosphatase#PC00196;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004911.1|UniProtKB=W5MBZ6 W5MBZ6 PTHR33443:SF30 ZGC:112980 OS03G0140900 PROTEIN LEPOC|Ensembl=ENSLOCG00000009729.1|UniProtKB=W5MU27 W5MU27 EIF3A PTHR14005:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000018200.1|UniProtKB=W5NNU2 W5NNU2 PTHR36684:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX14 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX14 HOMOLOG chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013301.1|UniProtKB=W5N6Y2 W5N6Y2 PTHR11250:SF5 TACHYKININ TACHYKININ 4 LEPOC|Ensembl=ENSLOCG00000009695.1|UniProtKB=W5MTY1 W5MTY1 PTHR45682:SF4 AGAP008228-PA SERINE_THREONINE_TYROSINE-INTERACTING-LIKE PROTEIN 2 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000004168.1|UniProtKB=W5M9D1 W5M9D1 PTHR45629:SF15 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000012872.1|UniProtKB=W5N5D9 W5N5D9 PTHR13703:SF63 SMAD SMAD FAMILY MEMBER 4 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;response to transforming growth factor beta#GO:0071559;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>Smad4#P01455;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>Co-Smads#P01276 LEPOC|Ensembl=ENSLOCG00000004781.1|UniProtKB=W5MBK4 W5MBK4 PTHR24103:SF596 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 54 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016199.1|UniProtKB=W5NH60 W5NH60 PTHR45924:SF1 FI17866P1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 1 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 LEPOC|Ensembl=ENSLOCG00000005824.1|UniProtKB=W5MF76 W5MF76 PTHR21420:SF3 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neurotic#P01115 LEPOC|Ensembl=ENSLOCG00000004785.1|UniProtKB=W5MBI2 W5MBI2 PTHR28637:SF1 DNA REPLICATION FACTOR CDT1 DNA REPLICATION FACTOR CDT1 enzyme binding#GO:0019899;binding#GO:0005488;nucleic acid binding#GO:0003676;protein binding#GO:0005515;DNA binding#GO:0003677 cell communication#GO:0007154;regulation of DNA replication#GO:0006275;intracellular signal transduction#GO:0035556;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of DNA-templated DNA replication#GO:0090329;cellular response to stimulus#GO:0051716;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;DNA integrity checkpoint signaling#GO:0031570;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell cycle checkpoint signaling#GO:0000075;regulation of DNA-templated DNA replication initiation#GO:0030174;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000012210.1|UniProtKB=W5N314 W5N314 PTHR12196:SF2 DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN DIPHTHINE--AMMONIA LIGASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;metabolic process#GO:0008152;protein modification process#GO:0036211;primary metabolic process#GO:0044238 LEPOC|Ensembl=ENSLOCG00000002316.1|UniProtKB=W5M2V1 W5M2V1 PTHR10993:SF7 OCTANOYLTRANSFERASE OCTANOYL-[ACYL-CARRIER-PROTEIN]:PROTEIN N-OCTANOYLTRANSFERASE LIPT2, MITOCHONDRIAL acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 transferase#PC00220 Lipoate_biosynthesis#P02750>Lipoyl-protein ligase#P03003 LEPOC|Ensembl=ENSLOCG00000000258.1|UniProtKB=W5LVX6 W5LVX6 PTHR14241:SF1 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 LEPOC|Ensembl=ENSLOCG00000004086.1|UniProtKB=W5M915 W5M915 PTHR11723:SF4 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;nervous system development#GO:0007399;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014267.1|UniProtKB=W5NAB0 W5NAB0 PTHR24261:SF12 PLASMINOGEN-RELATED HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN-RELATED kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;receptor tyrosine kinase binding#GO:0030971;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008138.1|UniProtKB=W5MNB6 W5MNB6 PTHR43856:SF3 CARDIOLIPIN HYDROLASE MITOCHONDRIAL CARDIOLIPIN HYDROLASE nuclease activity#GO:0004518;hydrolase activity#GO:0016787;lipase activity#GO:0016298;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;catalytic activity, acting on a nucleic acid#GO:0140640 anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;germ cell development#GO:0007281;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental process#GO:0032502;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;gene expression#GO:0010467;oogenesis#GO:0048477;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000008747.1|UniProtKB=W5MQJ0 W5MQJ0 PTHR45937:SF2 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 developmental process#GO:0032502;striated muscle tissue development#GO:0014706;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;muscle organ development#GO:0007517;connective tissue development#GO:0061448;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;animal organ development#GO:0048513;skeletal muscle tissue development#GO:0007519;muscle structure development#GO:0061061;tissue development#GO:0009888 LEPOC|Ensembl=ENSLOCG00000000879.1|UniProtKB=W5LXX3 W5LXX3 PTHR10082:SF28 INTEGRIN BETA SUBUNIT INTEGRIN BETA-1 collagen binding#GO:0005518;kinase binding#GO:0019900;binding#GO:0005488;signaling receptor binding#GO:0005102;protein kinase binding#GO:0019901;laminin binding#GO:0043236;enzyme binding#GO:0019899;protein binding#GO:0005515;extracellular matrix binding#GO:0050840;protein-containing complex binding#GO:0044877;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;integrin binding#GO:0005178;cytokine binding#GO:0019955 cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;signaling#GO:0023052;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627;biological regulation#GO:0065007;cell migration#GO:0016477;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;signaling receptor complex#GO:0043235;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;synapse#GO:0045202;cellular anatomical structure#GO:0110165;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;integrin complex#GO:0008305 integrin#PC00126 CCKR signaling map#P06959>ITGB1#P07113;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin beta#P00931;CCKR signaling map#P06959>ITGB1#G06984;CCKR signaling map#P06959>ITGB1#G07277;Gonadotropin-releasing hormone receptor pathway#P06664>alpha-beta integrin dimer#P06820 LEPOC|Ensembl=ENSLOCG00000003602.1|UniProtKB=W5M7A9 W5M7A9 PTHR10334:SF63 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 15 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002876.1|UniProtKB=W5M4S5 W5M4S5 PTHR46600:SF2 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 1 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000015743.1|UniProtKB=W5NFH1 W5NFH1 UNC93A PTHR19444:SF13 UNC-93 RELATED N-ACETYLGLUCOSAMINE TRANSPORTER UNC93A transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000017828.1|UniProtKB=W5NMS2 W5NMS2 PTHR28649:SF2 PROTEIN REPRIMO-RELATED REPRIMO, TP53 DEPENDENT G2 ARREST MEDIATOR HOMOLOG LEPOC|Ensembl=ENSLOCG00000017167.1|UniProtKB=W5NKR1 W5NKR1 PTHR15189:SF8 BRISC AND BRCA1-A COMPLEX MEMBER 2 BRISC AND BRCA1-A COMPLEX MEMBER 2 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000016206.1|UniProtKB=W5NH67 W5NH67 PTHR47249:SF1 VACUOLAR PROTEIN 8 VACUOLAR PROTEIN 8 LEPOC|Ensembl=ENSLOCG00000013275.1|UniProtKB=W5N6V1 W5N6V1 PTHR31626:SF3 SUSHI DOMAIN-CONTAINING PROTEIN PROTEIN FAM171A2 LEPOC|Ensembl=ENSLOCG00000016379.1|UniProtKB=W5NHW8 W5NHW8 PTHR44019:SF1 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG B cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000008466.1|UniProtKB=W5MPJ0 W5MPJ0 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;cell communication#GO:0007154;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009476.1|UniProtKB=W5MT56 W5MT56 PTHR35069:SF1 PROTEIN C9ORF135 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 95 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000007368.1|UniProtKB=W5MKN5 W5MKN5 PTHR13742:SF20 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-LIKE PROTEIN 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;negative regulation of cell cycle process#GO:0010948;negative regulation of cell cycle#GO:0045786;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway feedback loops 2#P04398>Rb#P04654 LEPOC|Ensembl=ENSLOCG00000001189.1|UniProtKB=W5LYZ3 W5LYZ3 PTHR13723:SF159 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PLAC DOMAIN-CONTAINING PROTEIN metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000007237.1|UniProtKB=W5MK54 W5MK54 PTHR24351:SF236 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011762.1|UniProtKB=W5N1F7 W5N1F7 PTHR22812:SF162 CHROMOBOX PROTEIN CHROMOBOX 3 chromatin binding#GO:0003682;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014798.1|UniProtKB=W5NC64 W5NC64 PTHR15666:SF1 COMM DOMAIN CONTAINING PROTEIN 5 COMM DOMAIN-CONTAINING PROTEIN 5 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007187.1|UniProtKB=W5MJZ1 W5MJZ1 PTHR10519:SF74 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;signaling receptor complex#GO:0043235 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 LEPOC|Ensembl=ENSLOCG00000009145.1|UniProtKB=W5MRZ2 W5MRZ2 PTHR45616:SF26 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 8 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;supramolecular fiber organization#GO:0097435 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000015349.1|UniProtKB=W5NE31 W5NE31 PTHR11849:SF156 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000004601.1|UniProtKB=W5MAV9 W5MAV9 PTHR45864:SF5 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 1 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488;actin binding#GO:0003779 regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 LEPOC|Ensembl=ENSLOCG00000014028.1|UniProtKB=W5N9I1 W5N9I1 PTHR14198:SF23 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED SI:CH211-137I24.10 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009620.1|UniProtKB=W5MTP2 W5MTP2 PTHR16705:SF6 COMPLEXIN COMPLEXIN-1 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 regulated exocytosis#GO:0045055;regulation of transport#GO:0051049;exocytosis#GO:0006887;regulation of localization#GO:0032879;vesicle-mediated transport in synapse#GO:0099003;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component organization#GO:0051128;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916 membrane#GO:0016020;presynapse#GO:0098793;neuron projection#GO:0043005;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cell junction#GO:0030054;axon terminus#GO:0043679;membrane protein complex#GO:0098796;synapse#GO:0045202;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;terminal bouton#GO:0043195;cell projection#GO:0042995;neuron projection terminus#GO:0044306;axon#GO:0030424;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008841.1|UniProtKB=W5MQV0 W5MQV0 PTHR45828:SF51 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000018287.1|UniProtKB=W5NP29 W5NP29 PTHR12002:SF176 CLAUDIN CLAUDIN-4 cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000001557.1|UniProtKB=W5M089 W5M089 PTHR45911:SF3 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of neurotransmitter secretion#GO:0046928;regulation of biological process#GO:0050789;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;presynapse#GO:0098793;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503 LEPOC|Ensembl=ENSLOCG00000006212.1|UniProtKB=W5MGJ3 W5MGJ3 PTHR35088:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 178 COILED-COIL DOMAIN-CONTAINING PROTEIN 178 LEPOC|Ensembl=ENSLOCG00000006277.1|UniProtKB=W5MGS4 W5MGS4 PTHR12081:SF42 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000002535.1|UniProtKB=W5M3L5 W5M3L5 PTHR21100:SF9 PREFOLDIN SUBUNIT 4 PREFOLDIN SUBUNIT 4 protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000006371.1|UniProtKB=W5MH31 W5MH31 PTHR11265:SF0 S-ADENOSYL-METHYLTRANSFERASE MRAW 12S RRNA N(4)-CYTIDINE METHYLTRANSFERASE METTL15 N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;rRNA base methylation#GO:0070475;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000010756.1|UniProtKB=W5MXS4 W5MXS4 PTHR10454:SF240 CASPASE CASPASE-10 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 positive regulation of apoptotic process#GO:0043065;positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;regulation of neuron apoptotic process#GO:0043523;cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 Huntington disease#P00029>Caspase 8#P00808;FAS signaling pathway#P00020>Pro-Caspase10#P00598;Apoptosis signaling pathway#P00006>Caspase 10#P00295;Huntington disease#P00029>Pro-caspase 8#P00767;FAS signaling pathway#P00020>Caspase8#P00594;FAS signaling pathway#P00020>Pro-Caspase8#P00604;FAS signaling pathway#P00020>Caspase10#P00606;Apoptosis signaling pathway#P00006>Caspase 8#P00299 LEPOC|Ensembl=ENSLOCG00000007564.1|UniProtKB=W5MLB5 W5MLB5 PTHR40141:SF2 3',5'-CYCLIC-AMP PHOSPHODIESTERASE-RELATED 3',5'-CYCLIC-AMP PHOSPHODIESTERASE LEPOC|Ensembl=ENSLOCG00000005624.1|UniProtKB=W5MEJ4 W5MEJ4 PTHR19384:SF56 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE, INDUCIBLE nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monooxygenase activity#GO:0004497;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;circulatory system process#GO:0003013;response to bacterium#GO:0009617;inflammatory response#GO:0006954;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to external biotic stimulus#GO:0043207;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;defense response#GO:0006952;system process#GO:0003008;response to external stimulus#GO:0009605;proteinogenic amino acid metabolic process#GO:0170039;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;response to other organism#GO:0051707;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of blood pressure#GO:0008217;carboxylic acid catabolic process#GO:0046395;regulation of biological quality#GO:0065008;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;carboxylic acid metabolic process#GO:0019752;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to molecule of bacterial origin#GO:0002237;response to lipopolysaccharide#GO:0032496;metabolic process#GO:0008152;response to lipid#GO:0033993;response to chemical#GO:0042221;intracellular signaling cassette#GO:0141124;arginine metabolic process#GO:0006525;response to stress#GO:0006950;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;signal transduction#GO:0007165 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;nucleus#GO:0005634;cytosol#GO:0005829;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 PI3 kinase pathway#P00048>NOS#P01205 LEPOC|Ensembl=ENSLOCG00000011443.1|UniProtKB=W5N099 W5N099 PTHR11556:SF13 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE ISOZYME 2 hydrolase activity, acting on ester bonds#GO:0016788;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;small molecule biosynthetic process#GO:0044283;glucose metabolic process#GO:0006006;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase#PC00181;hydrolase#PC00121;carbohydrate phosphatase#PC00066 LEPOC|Ensembl=ENSLOCG00000010541.1|UniProtKB=W5MX07 W5MX07 PTHR15191:SF8 PROTEIN CBG20567 PITUITARY TUMOR-TRANSFORMING GENE 1 PROTEIN-INTERACTING PROTEIN intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;protein localization to organelle#GO:0033365 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016069.1|UniProtKB=W5NGP0 W5NGP0 PTHR11848:SF320 TGF-BETA FAMILY NODAL-RELATED 1-RELATED receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000004290.1|UniProtKB=W5M9S8 W5M9S8 PTHR12587:SF18 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-BETA-2 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;neuromuscular junction development#GO:0007528;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 synapse#GO:0045202;presynaptic active zone#GO:0048786;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;presynapse#GO:0098793 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001005.1|UniProtKB=W5LYC8 W5LYC8 PTHR19964:SF35 MULTIPLE PDZ DOMAIN PROTEIN PDZ DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009943.1|UniProtKB=W5MUV5 W5MUV5 PTHR19964:SF11 MULTIPLE PDZ DOMAIN PROTEIN INAD-LIKE PROTEIN cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;tight junction#GO:0070160;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;apical junction complex#GO:0043296;apical part of cell#GO:0045177 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016538.1|UniProtKB=W5NIG7 W5NIG7 PTHR45808:SF4 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 8 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 negative regulation of cellular process#GO:0048523;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 VEGF signaling pathway#P00056>Rac#P01421;PDGF signaling pathway#P00047>Rho#P01174;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520;Angiogenesis#P00005>Rac#P00245 LEPOC|Ensembl=ENSLOCG00000014823.1|UniProtKB=W5NC92 W5NC92 PTHR11022:SF58 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN RECOGNITION PROTEIN 1 signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;pattern recognition receptor activity#GO:0038187;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017852.1|UniProtKB=W5NMU6 W5NMU6 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000001639.1|UniProtKB=W5M0H7 W5M0H7 PTHR28627:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5 mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009132.1|UniProtKB=W5MRX6 W5MRX6 PTHR12752:SF2 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PDZ AND PLECKSTRIN HOMOLOGY DOMAINS 1 LEPOC|Ensembl=ENSLOCG00000011379.1|UniProtKB=W5N026 W5N026 PTHR24229:SF42 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 LEPOC|Ensembl=ENSLOCG00000013281.1|UniProtKB=W5N6V8 W5N6V8 PTHR10627:SF70 SCP160 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 6 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014580.1|UniProtKB=W5NBD8 W5NBD8 PTHR10865:SF5 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA1 binding#GO:0005488;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription coactivator activity#GO:0003713;histone deacetylase binding#GO:0042826 negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;response to ionizing radiation#GO:0010212;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to abiotic stimulus#GO:0009628;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;cellular response to stress#GO:0033554;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;double-strand break repair#GO:0006302;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;response to radiation#GO:0009314;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;DNA damage response#GO:0006974;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015434.1|UniProtKB=W5NED9 W5NED9 PTHR12372:SF5 PECANEX PECANEX-LIKE PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000015178.1|UniProtKB=W5NDG8 W5NDG8 PTHR12091:SF0 MELANIN-CONCENTRATING HORMONE PRO-MCH protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;neuropeptide receptor binding#GO:0071855;G protein-coupled receptor binding#GO:0001664 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648 peptide hormone#PC00179;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000005186.1|UniProtKB=W5MCY7 W5MCY7 PTHR15923:SF1 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN LIPOLYSIS-STIMULATED LIPOPROTEIN RECEPTOR animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cell development#GO:0048468;cell junction organization#GO:0034330;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003329.1|UniProtKB=W5M6C8 W5M6C8 PTHR21184:SF4 MENORIN (DENDRITIC BRANCHING PROTEIN) PROTEIN FAM151A cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000011938.1|UniProtKB=W5N227 W5N227 PTHR12277:SF69 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD12B catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 glycerophospholipid metabolic process#GO:0006650;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;neutral lipid metabolic process#GO:0006638;acylglycerol catabolic process#GO:0046464;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;modified amino acid metabolic process#GO:0006575;organophosphate catabolic process#GO:0046434;glycerolipid catabolic process#GO:0046503 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000016994.1|UniProtKB=W5NK54 W5NK54 SLC6A13 PTHR11616:SF111 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 2 carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725 plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000002109.1|UniProtKB=W5M245 W5M245 PTHR11636:SF81 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000001734.1|UniProtKB=W5M0X6 W5M0X6 PTHR11923:SF110 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 SCAVENGER RECEPTOR CLASS B MEMBER 1 protein-lipid complex binding#GO:0071814;low-density lipoprotein particle binding#GO:0030169;binding#GO:0005488;lipoprotein particle binding#GO:0071813;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;cargo receptor activity#GO:0038024 phagocytosis#GO:0006909;transport#GO:0006810;import into cell#GO:0098657;plasma lipoprotein particle clearance#GO:0034381;sterol transport#GO:0015918;establishment of localization#GO:0051234;apoptotic cell clearance#GO:0043277;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cholesterol efflux#GO:0033344;cellular process#GO:0009987;multicellular organismal process#GO:0032501;lipid transport#GO:0006869;biological regulation#GO:0065007;lipid localization#GO:0010876;cell recognition#GO:0008037;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;regulation of biological process#GO:0050789;endocytosis#GO:0006897 plasma membrane region#GO:0098590;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane raft#GO:0045121;caveola#GO:0005901;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane raft#GO:0044853;membrane microdomain#GO:0098857 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000009367.1|UniProtKB=W5MSR5 W5MSR5 PTHR23277:SF12 NECTIN-RELATED NECTIN-3 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;protein binding#GO:0005515 cell adhesion#GO:0007155;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical junction complex#GO:0043296;cell junction#GO:0030054;anchoring junction#GO:0070161;adherens junction#GO:0005912 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000003778.1|UniProtKB=W5M803 W5M803 GFM1 PTHR43636:SF2 ELONGATION FACTOR G, MITOCHONDRIAL ELONGATION FACTOR G, MITOCHONDRIAL translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000005605.1|UniProtKB=W5MEG5 W5MEG5 PTHR12610:SF30 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 4 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006492.1|UniProtKB=W5MHI9 W5MHI9 PTHR11371:SF29 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1-LIKE 2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;DNA binding#GO:0003677;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;DNA catabolic process#GO:0006308;metabolic process#GO:0008152;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000001593.1|UniProtKB=W5M0C2 W5M0C2 PTHR13287:SF2 ADIPOSE-SECRETED SIGNALING PROTEIN ADIPOSE-SECRETED SIGNALING PROTEIN signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013242.1|UniProtKB=W5N6Q4 W5N6Q4 PTHR13815:SF7 GOLGIN-84 GOLGIN SUBFAMILY A MEMBER 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;retrograde transport, vesicle recycling within Golgi#GO:0000301;organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256 Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi stack#GO:0005795;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013115.1|UniProtKB=W5N6B1 W5N6B1 PTHR24347:SF365 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT DELTA transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515 regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008;regulation of neuronal synaptic plasticity#GO:0048168;regulation of signaling#GO:0023051;regulation of synaptic plasticity#GO:0048167;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;axon#GO:0030424;postsynaptic density#GO:0014069;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron to neuron synapse#GO:0098984;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;postsynapse#GO:0098794;neuron projection#GO:0043005 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 LEPOC|Ensembl=ENSLOCG00000014807.1|UniProtKB=W5NC80 W5NC80 PTHR43903:SF4 NEUROLIGIN NEUROLIGIN-3 binding#GO:0005488;signaling receptor binding#GO:0005102;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor activity#GO:0038023 membrane organization#GO:0061024;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;synaptic vesicle endocytosis#GO:0048488;chemical synaptic transmission#GO:0007268;postsynapse organization#GO:0099173;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;regulation of biological process#GO:0050789;membrane assembly#GO:0071709;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;signaling#GO:0023052;endocytosis#GO:0006897;synapse assembly#GO:0007416;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;cellular localization#GO:0051641 membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;cell surface#GO:0009986;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000013185.1|UniProtKB=W5N6I3 W5N6I3 PTHR11417:SF75 SOMATOTROPIN,PROLACTIN GROWTH HORMONE 1 molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to hormone#GO:0009725;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;animal organ development#GO:0048513;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;positive regulation of response to stimulus#GO:0048584;cellular response to nitrogen compound#GO:1901699;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;regulation of receptor signaling pathway via STAT#GO:1904892;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000014572.1|UniProtKB=W5NBC2 W5NBC2 PTHR11849:SF178 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ELK#P00890;CCKR signaling map#P06959>ELK1#P07146;Toll receptor signaling pathway#P00054>Elk1#P01341;p38 MAPK pathway#P05918>ELK#P06013;Interleukin signaling pathway#P00036>ELK#P00962;PDGF signaling pathway#P00047>ELK#P01140;Ras Pathway#P04393>Elk-1#P04573;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>ELK1#P05934;Gonadotropin-releasing hormone receptor pathway#P06664>ELK1#P06785;Oxidative stress response#P00046>Elk-1#P01136;Parkinson disease#P00049>Elk-1#P01233 LEPOC|Ensembl=ENSLOCG00000005150.1|UniProtKB=W5MCU2 W5MCU2 PTHR21433:SF2 TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA TRANSMEMBRANE PROTEIN 120B cellular developmental process#GO:0048869;cell differentiation#GO:0030154;fat cell differentiation#GO:0045444;cellular process#GO:0009987;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967 LEPOC|Ensembl=ENSLOCG00000010536.1|UniProtKB=W5MX13 W5MX13 PTHR10924:SF3 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED CHOLINE_ETHANOLAMINE TRANSPORTER FLVCR2 tetrapyrrole binding#GO:0046906;binding#GO:0005488;heme binding#GO:0020037;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;iron coordination entity transport#GO:1901678;metal ion transport#GO:0030001;nitrogen compound transport#GO:0071705 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000004082.1|UniProtKB=W5M949 W5M949 PTHR19432:SF6 SUGAR TRANSPORTER PROTON-ASSOCIATED SUGAR TRANSPORTER A carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014011.1|UniProtKB=W5N9G2 W5N9G2 PTHR10183:SF405 CALPAIN CALPAIN 5-LIKE catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000622.1|UniProtKB=W5LX31 W5LX31 PTHR47454:SF1 RING FINGER PROTEIN 224 RING FINGER PROTEIN 224 LEPOC|Ensembl=ENSLOCG00000000964.1|UniProtKB=W5LY69 W5LY69 PTHR24228:SF10 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G PROTEIN-COUPLED RECEPTOR 15 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;signaling#GO:0023052;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;tube morphogenesis#GO:0035239;cell communication#GO:0007154;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;system development#GO:0048731;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;tube development#GO:0035295;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;developmental process#GO:0032502 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008657.1|UniProtKB=W5MQ76 W5MQ76 PTHR12601:SF41 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3 CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 organelle localization#GO:0051640;localization#GO:0051179;mitochondrion localization#GO:0051646 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000002800.1|UniProtKB=W5M4J0 W5M4J0 PTHR12924:SF1 TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010108.1|UniProtKB=W5MVH0 W5MVH0 PTHR10997:SF9 IMPORTIN-7, 8, 11 IMPORTIN-9 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594 organelle envelope#GO:0031967;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013831.1|UniProtKB=W5N8V5 W5N8V5 PTHR14456:SF2 INOSITOL POLYPHOSPHATE KINASE 1 INOSITOL-PENTAKISPHOSPHATE 2-KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000002578.1|UniProtKB=W5M3U5 W5M3U5 PTHR11792:SF24 ARRESTIN BETA-ARRESTIN-1 G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 system process#GO:0003008;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;regulation of response to stimulus#GO:0048583;transport#GO:0006810;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;cellular process#GO:0009987;receptor internalization#GO:0031623;negative regulation of cell communication#GO:0010648;localization#GO:0051179;sensory perception#GO:0007600;regulation of signaling#GO:0023051;nervous system process#GO:0050877;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007262.1|UniProtKB=W5MK81 W5MK81 PTHR24025:SF21 DESMOGLEIN FAMILY MEMBER FAT ATYPICAL CADHERIN 3B metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000016238.1|UniProtKB=W5NHB6 W5NHB6 PTHR21563:SF3 ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000007704.1|UniProtKB=W5MLU9 W5MLU9 PTHR12112:SF21 BNIP - RELATED BCL-2_ADENOVIRUS E1B 19 KDA-INTERACTING PROTEIN 2-LIKE PROTEIN cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915;programmed cell death#GO:0012501 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000004732.1|UniProtKB=W5MBB2 W5MBB2 PTHR31281:SF0 PROTEIN FAM219A PROTEIN FAM219A LEPOC|Ensembl=ENSLOCG00000009621.1|UniProtKB=W5MTQ4 W5MTQ4 PTHR24223:SF166 ATP-BINDING CASSETTE SUB-FAMILY C ATP BINDING CASSETTE SUBFAMILY C MEMBER 13 (PSEUDO xenobiotic transmembrane transporter activity#GO:0042910;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000014553.1|UniProtKB=W5NBA1 W5NBA1 PTHR48092:SF21 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN-RELATED RECEPTOR GAMMA transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000001437.1|UniProtKB=W5LZV1 W5LZV1 PTHR14898:SF4 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB HOMOLOG 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000001558.1|UniProtKB=W5M076 W5M076 PTHR11633:SF3 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR SUBUNIT A protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;growth factor receptor binding#GO:0070851 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;positive regulation of cell motility#GO:2000147;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of signal transduction#GO:0009967;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;tube development#GO:0035295;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;positive regulation of MAPK cascade#GO:0043410;positive regulation of locomotion#GO:0040017;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 PDGF signaling pathway#P00047>PDGF#P01170;Angiogenesis#P00005>PDGF#P00224 LEPOC|Ensembl=ENSLOCG00000000294.1|UniProtKB=W5LW17 W5LW17 PTHR44324:SF4 WD40 REPEAT DOMAIN 95 WD40 REPEAT DOMAIN 95 LEPOC|Ensembl=ENSLOCG00000002491.1|UniProtKB=W5M3H7 W5M3H7 PTHR13482:SF3 MICRORNA PROCESSOR COMPLEX SUBUNIT DGCR8 MICROPROCESSOR COMPLEX SUBUNIT DGCR8 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;primary miRNA processing#GO:0031053;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000007289.1|UniProtKB=W5MKC3 W5MKC3 PTHR21560:SF0 VERY KIND PROTEIN KINASE NON-CATALYTIC C-LOBE DOMAIN-CONTAINING PROTEIN 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;regulation of neuron projection development#GO:0010975;regulation of dendrite morphogenesis#GO:0048814;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;regulation of cellular component organization#GO:0051128;regulation of cell projection organization#GO:0031344;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035 dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular protein-containing complex#GO:0140535;cell body#GO:0044297;neuron projection#GO:0043005;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995 G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000013164.1|UniProtKB=W5N6G2 W5N6G2 PTHR44675:SF1 PAK1 INTERACTING PROTEIN 1 P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000011532.1|UniProtKB=W5N0L0 W5N0L0 PTHR31169:SF4 OS05G0300700 PROTEIN CELL DIVISION CYCLE-ASSOCIATED 7-LIKE PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000015164.1|UniProtKB=W5NDF6 W5NDF6 PTHR22826:SF146 RHO GUANINE EXCHANGE FACTOR-RELATED PROTO-ONCOGENE DBL guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 cellular component organization#GO:0016043;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;dendrite development#GO:0016358;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007491.1|UniProtKB=W5ML35 W5ML35 PTHR24073:SF1242 DRAB5-RELATED RAS-RELATED PROTEIN RAB-18 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;lipid droplet organization#GO:0034389 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000001745.1|UniProtKB=W5M102 W5M102 PTHR18916:SF95 DYNACTIN 1-RELATED MICROTUBULE-BINDING DYNACTIN SUBUNIT 1 localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;spindle localization#GO:0051653;cellular localization#GO:0051641;establishment or maintenance of cell polarity#GO:0007163;organelle localization#GO:0051640;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;establishment of cell polarity#GO:0030010;nuclear migration#GO:0007097;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;establishment of localization in cell#GO:0051649;establishment of spindle localization#GO:0051293;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;axon#GO:0030424;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;neuron projection#GO:0043005;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793 chaperone#PC00072 Huntington disease#P00029>Dynactin#P00781 LEPOC|Ensembl=ENSLOCG00000008024.1|UniProtKB=W5MMY4 W5MMY4 PTHR31761:SF1 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEINS-INTERACTING PROTEIN 1 GADD45GIP1 LARGE RIBOSOMAL SUBUNIT PROTEIN ML64 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015642.1|UniProtKB=W5NF47 W5NF47 PTHR15526:SF5 MUSKELIN MUSKELIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004431.1|UniProtKB=W5MA90 W5MA90 PTHR43327:SF10 STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009786.1|UniProtKB=W5MU97 W5MU97 PTHR14198:SF22 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 19 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000008016.1|UniProtKB=W5MMX8 W5MMX8 PTHR31728:SF1 ABRAXAS FAMILY MEMBER BRISC COMPLEX SUBUNIT ABRAXAS 2 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;organelle localization#GO:0051640;organelle assembly#GO:0070925;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;spindle organization#GO:0007051;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;mitotic spindle organization#GO:0007052;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;nuclear division#GO:0000280;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;cytoskeleton organization#GO:0007010;attachment of spindle microtubules to kinetochore#GO:0008608;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000006195.1|UniProtKB=W5MGH4 W5MGH4 PTHR45644:SF2 AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED OUTER MITOCHONDRIAL TRANSMEMBRANE HELIX TRANSLOCASE localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of protein localization to membrane#GO:0090150;localization within membrane#GO:0051668;establishment of protein localization#GO:0045184;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000009381.1|UniProtKB=W5MST7 W5MST7 PTHR48408:SF1 FAMILY NOT NAMED XYLOSE ISOMERASE LEPOC|Ensembl=ENSLOCG00000000736.1|UniProtKB=W5LXF5 W5LXF5 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;immune response#GO:0006955;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015314.1|UniProtKB=W5NDY6 W5NDY6 PTHR11242:SF1 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN LIKE 1 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein modification process#GO:0036211;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 membrane#GO:0016020;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008779.1|UniProtKB=W5MQM9 W5MQM9 PTHR24103:SF611 E3 UBIQUITIN-PROTEIN LIGASE TRIM BBOX AND DUF4200 DOMAIN-CONTAINING PROTEIN-RELATED acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006989.1|UniProtKB=W5MJ95 W5MJ95 PTHR19297:SF178 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 7-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000000235.1|UniProtKB=W5LVV3 W5LVV3 PTHR10250:SF2 MICROSOMAL GLUTATHIONE S-TRANSFERASE ARACHIDONATE 5-LIPOXYGENASE-ACTIVATING PROTEIN glutathione transferase activity#GO:0004364;lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491 small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;icosanoid metabolic process#GO:0006690;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transferase#PC00220 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 LEPOC|Ensembl=ENSLOCG00000018121.1|UniProtKB=W5NNL3 W5NNL3 PTHR43515:SF1 THREONINE SYNTHASE-LIKE 1 THREONINE SYNTHASE-LIKE 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 Threonine biosynthesis#P02781>Threonine synthase#P03190 LEPOC|Ensembl=ENSLOCG00000003912.1|UniProtKB=W5M8F9 W5M8F9 PTHR23349:SF62 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST MUSCULIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;regulation of RNA metabolic process#GO:0051252;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal muscle tissue development#GO:0007519;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;muscle organ development#GO:0007517;developmental process#GO:0032502;striated muscle tissue development#GO:0014706 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011789.1|UniProtKB=W5N1I9 W5N1I9 PTHR15129:SF2 SRC-ASSOCIATED ADAPTOR PROTEIN SRC KINASE-ASSOCIATED PHOSPHOPROTEIN 2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016516.1|UniProtKB=W5NIE2 W5NIE2 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008469.1|UniProtKB=W5MPK0 W5MPK0 PTHR31997:SF0 AGAP003710-PA PRIMARY CILIUM ASSEMBLY PROTEIN FAM149B1 cilium organization#GO:0044782;localization#GO:0051179;organelle assembly#GO:0070925;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;cilium assembly#GO:0060271;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036 LEPOC|Ensembl=ENSLOCG00000018079.1|UniProtKB=W5NNH1 W5NNH1 PTHR45617:SF189 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH ALPHA-2-GLYCOPROTEIN PRECURSOR scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003821.1|UniProtKB=W5M860 W5M860 PTHR10529:SF257 AP COMPLEX SUBUNIT MU AP-1 COMPLEX SUBUNIT MU-1 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;post-Golgi vesicle-mediated transport#GO:0006892;Golgi to vacuole transport#GO:0006896;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907 membrane coat#GO:0030117;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;coated membrane#GO:0048475;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular vesicle#GO:0097708;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin vesicle coat#GO:0030125;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;vesicle coat#GO:0030120 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015924.1|UniProtKB=W5NG47 W5NG47 PTHR10655:SF74 LYSOPHOSPHOLIPASE-RELATED LYSOPHOSPHOLIPASE-LIKE PROTEIN 1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;palmitoyl hydrolase activity#GO:0098599;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 regulation of protein localization to membrane#GO:1905475;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;negative regulation of protein transport#GO:0051224;negative regulation of transport#GO:0051051;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of transport#GO:0051049;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 lipase#PC00143;phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000009036.1|UniProtKB=W5MRK3 W5MRK3 PTHR11588:SF61 TUBULIN TUBULIN BETA CHAIN guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 tubulin#PC00228;cytoskeletal protein#PC00085 Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780 LEPOC|Ensembl=ENSLOCG00000016709.1|UniProtKB=W5NJ33 W5NJ33 PTHR13252:SF9 F-BOX ONLY PROTEIN 28 F-BOX ONLY PROTEIN 28 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 LEPOC|Ensembl=ENSLOCG00000020981.1|UniProtKB=Q8HQN1 Q8HQN1 PTHR10422:SF18 CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 1 catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324 electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277 oxidase#PC00175;oxidoreductase#PC00176 ATP synthesis#P02721>Cytochrome oxidase aa3#P02793 LEPOC|Ensembl=ENSLOCG00000005042.1|UniProtKB=W5MCG7 W5MCG7 PTHR13723:SF24 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 14 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000003760.1|UniProtKB=W5M7Z2 W5M7Z2 PTHR21119:SF8 C2 DOMAIN-CONTAINING PROTEIN PHOSPHOLIPID TRANSFER PROTEIN C2CD2L small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ion binding#GO:0043167;lipid transfer activity#GO:0120013;phosphatidylinositol binding#GO:0035091;transporter activity#GO:0005215;phosphatidylinositol transfer activity#GO:0008526 positive regulation of protein secretion#GO:0050714;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of insulin secretion#GO:0050796;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;positive regulation of signaling#GO:0023056;regulation of hormone secretion#GO:0046883;regulation of secretion#GO:0051046;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of hormone levels#GO:0010817;regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of cell communication#GO:0010646 cytoplasmic side of membrane#GO:0098562;apical part of cell#GO:0045177;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004263.1|UniProtKB=W5M9N8 W5M9N8 PTHR45679:SF10 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 carbohydrate derivative metabolic process#GO:1901135;endoplasmic reticulum unfolded protein response#GO:0030968;biological regulation#GO:0065007;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;protein metabolic process#GO:0019538;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of biological process#GO:0050789;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to unfolded protein#GO:0006986 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000010861.1|UniProtKB=W5MY49 W5MY49 PTHR32235:SF1 NON-HOMOLOGOUS END-JOINING FACTOR 1 NON-HOMOLOGOUS END-JOINING FACTOR 1 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;DNA repair complex#GO:1990391;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000005546.1|UniProtKB=W5ME87 W5ME87 PTHR46512:SF3 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP8 regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;protein folding#GO:0006457;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of BMP signaling pathway#GO:0030510;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;biosynthetic process#GO:0009058;regulation of signal transduction#GO:0009966;gene expression#GO:0010467;protein maturation#GO:0051604;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152;positive regulation of BMP signaling pathway#GO:0030513;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;cytosol#GO:0005829;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002543.1|UniProtKB=W5M3M4 W5M3M4 PTHR19918:SF4 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG B enzyme activator activity#GO:0008047;binding#GO:0005488;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of metabolic process#GO:0009893;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;proteasomal protein catabolic process#GO:0010498;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;metabolic process#GO:0008152;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;primary metabolic process#GO:0044238;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;protein metabolic process#GO:0019538;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017394.1|UniProtKB=W5NLJ0 W5NLJ0 PTHR24366:SF175 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS PLATELET GLYCOPROTEIN IB ALPHA CHAIN immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000006889.1|UniProtKB=W5MIX2 W5MIX2 PTHR45655:SF7 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT ALPHA-2 cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;lyase activity#GO:0016829 response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cytosol#GO:0005829 guanylate cyclase#PC00114;cyclase#PC00079 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 LEPOC|Ensembl=ENSLOCG00000012706.1|UniProtKB=W5N4S2 W5N4S2 PTHR11844:SF24 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 2 endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;response to peptide#GO:1901652;negative regulation of protein catabolic process#GO:0042177;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;response to hormone#GO:0009725;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008626.1|UniProtKB=W5MQ56 W5MQ56 PTHR23169:SF20 ENVOPLAKIN PLECTIN structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198 cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cell-substrate junction assembly#GO:0007044;cell junction organization#GO:0034330;intermediate filament cytoskeleton organization#GO:0045104;response to stimulus#GO:0050896;intermediate filament-based process#GO:0045103;wound healing#GO:0042060;cellular process#GO:0009987;response to stress#GO:0006950;response to wounding#GO:0009611;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell-substrate junction organization#GO:0150115;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;perinuclear region of cytoplasm#GO:0048471;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cell periphery#GO:0071944;membrane#GO:0016020;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;sarcolemma#GO:0042383;cytoskeleton#GO:0005856;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 intermediate filament binding protein#PC00130;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000018177.1|UniProtKB=W5NNR9 W5NNR9 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014404.1|UniProtKB=W5NAS6 W5NAS6 PTHR43884:SF11 ACYL-COA DEHYDROGENASE VERY LONG-CHAIN ACYL-COA DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;lipid binding#GO:0008289 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329 membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010446.1|UniProtKB=W5MWR5 W5MWR5 PTHR24355:SF14 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 4 protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741 LEPOC|Ensembl=ENSLOCG00000011611.1|UniProtKB=W5N0W3 W5N0W3 PTHR23183:SF0 NOP14 NUCLEOLAR PROTEIN 14 biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003858.1|UniProtKB=W5M898 W5M898 PTHR14390:SF2 G PATCH DOMAIN CONTAINING PROTEIN 3 G PATCH DOMAIN-CONTAINING PROTEIN 3 ISOFORM X1 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 LEPOC|Ensembl=ENSLOCG00000000297.1|UniProtKB=W5LW16 W5LW16 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014031.1|UniProtKB=W5N9I6 W5N9I6 PTHR23019:SF2 NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210 organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008002.1|UniProtKB=W5MMW7 W5MMW7 PTHR10830:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 membrane protein complex#GO:0098796;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000014205.1|UniProtKB=W5NA38 W5NA38 PTHR15572:SF1 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 BRD4-INTERACTING CHROMATIN-REMODELING COMPLEX-ASSOCIATED PROTEIN regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355 chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000015075.1|UniProtKB=W5ND43 W5ND43 PTHR22576:SF41 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE CASPASE 14, APOPTOSIS-RELATED CYSTEINE PEPTIDASE negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000001910.1|UniProtKB=W5M1G1 W5M1G1 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;telomere organization#GO:0032200;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 LEPOC|Ensembl=ENSLOCG00000016137.1|UniProtKB=W5NGX4 W5NGX4 PTHR13206:SF0 UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN E3 UBIQUITIN-PROTEIN LIGASE FANCL acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015822.1|UniProtKB=W5NFS1 W5NFS1 PTHR15499:SF3 HMG BOX-CONTAINING PROTEIN 1 HMG BOX-CONTAINING PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 LEPOC|Ensembl=ENSLOCG00000004077.1|UniProtKB=W5M909 W5M909 PTHR45752:SF146 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 18 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012634.1|UniProtKB=W5N4K2 W5N4K2 PTHR23302:SF4 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 6 channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000002226.1|UniProtKB=W5M2I7 W5M2I7 PTHR14817:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 15 COILED-COIL DOMAIN-CONTAINING PROTEIN 15 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000002461.1|UniProtKB=W5M3D4 W5M3D4 PTHR46061:SF5 THYROTROPIN-RELEASING HORMONE RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH Receptor#P04580 LEPOC|Ensembl=ENSLOCG00000016680.1|UniProtKB=W5NJ02 W5NJ02 PTHR16193:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 27 TETRATRICOPEPTIDE REPEAT PROTEIN 27 LEPOC|Ensembl=ENSLOCG00000010409.1|UniProtKB=W5MWK8 W5MWK8 ITPA PTHR11067:SF9 INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN INOSINE TRIPHOSPHATE PYROPHOSPHATASE hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity#GO:0016787 cellular process#GO:0009987;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate catabolic process#GO:0046434 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000009765.1|UniProtKB=W5MU78 W5MU78 PTHR24278:SF26 COAGULATION FACTOR COAGULATION FACTOR VII serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;coagulation#GO:0050817;response to wounding#GO:0009611;response to stress#GO:0006950;biosynthetic process#GO:0009058;biological regulation#GO:0065007;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;metabolic process#GO:0008152;blood coagulation#GO:0007596;macromolecule metabolic process#GO:0043170;hemostasis#GO:0007599;primary metabolic process#GO:0044238;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;proteolysis#GO:0006508;wound healing#GO:0042060;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>FVII#P00454;Angiogenesis#P00005>FVIIa#P00201;Blood coagulation#P00011>FVIIa#P00447 LEPOC|Ensembl=ENSLOCG00000012754.1|UniProtKB=W5N4Z0 W5N4Z0 PTHR13723:SF151 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 17 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000016852.1|UniProtKB=W5NJM5 W5NJM5 PTHR46001:SF5 TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR TIAM2 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cell projection organization#GO:0031344;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of axonogenesis#GO:0050770;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000014076.1|UniProtKB=W5N9P5 W5N9P5 PTHR13902:SF10 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;channel regulator activity#GO:0016247;protein kinase activity#GO:0004672;molecular function inhibitor activity#GO:0140678;protein serine/threonine kinase activity#GO:0004674;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;transferase activity#GO:0016740;catalytic activity#GO:0003824;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 negative regulation of biological process#GO:0048519;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;negative regulation of transport#GO:0051051;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;monoatomic ion homeostasis#GO:0050801;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;regulation of monoatomic cation transmembrane transport#GO:1904062;chemical homeostasis#GO:0048878;regulation of transport#GO:0051049;regulation of localization#GO:0032879 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005849.1|UniProtKB=W5MFA7 W5MFA7 PTHR11347:SF23 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA' phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;system process#GO:0003008;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;visual perception#GO:0007601;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;sensory perception of light stimulus#GO:0050953;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;sensory perception#GO:0007600;nervous system process#GO:0050877;regulation of signaling#GO:0023051 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007678.1|UniProtKB=W5MLS0 W5MLS0 PTHR24115:SF546 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF14 cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544 establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;forebrain development#GO:0030900;central nervous system development#GO:0007417;animal gross anatomical part developmental process#GO:0160108;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;anatomical structure development#GO:0048856;cellular localization#GO:0051641;localization#GO:0051179;system development#GO:0048731;cellular process#GO:0009987;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;brain development#GO:0007420;nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;head development#GO:0060322;establishment of vesicle localization#GO:0051650;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;animal organ development#GO:0048513;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;vesicle cytoskeletal trafficking#GO:0099518 microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000005265.1|UniProtKB=W5MD80 W5MD80 PTHR13720:SF60 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 251 membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;sperm flagellum#GO:0036126 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001359.1|UniProtKB=W5LZJ1 W5LZJ1 PTHR23423:SF59 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008215.1|UniProtKB=W5MNL5 W5MNL5 PTHR13054:SF2 DIGEORGE SYNDROME CRITICAL REGION 6 DGCR6 FAMILY MEMBER PROTEIN DGCR6 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000004668.1|UniProtKB=W5MB33 W5MB33 PTHR12902:SF6 WASP-1 ACTIN-BINDING PROTEIN WASF2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein kinase A binding#GO:0051018;binding#GO:0005488;protein kinase A regulatory subunit binding#GO:0034237 regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;actin filament-based process#GO:0030029;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970 cell leading edge#GO:0031252;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000013322.1|UniProtKB=W5N709 W5N709 PTHR23254:SF17 EIF4G DOMAIN PROTEIN MIF4G DOMAIN-CONTAINING PROTEIN translation regulator activity#GO:0045182 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011933.1|UniProtKB=W5N219 W5N219 PTHR12818:SF0 TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a tRNA#GO:0140101 LEPOC|Ensembl=ENSLOCG00000002582.1|UniProtKB=W5M3S8 W5M3S8 PTHR24230:SF64 G-PROTEIN COUPLED RECEPTOR KISS1 RECEPTOR A transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005876.1|UniProtKB=W5MFD5 W5MFD5 PTHR31097:SF2 SI:DKEY-276J7.1 CHROMOSOME 7 OPEN READING FRAME 57 LEPOC|Ensembl=ENSLOCG00000004575.1|UniProtKB=W5MAS8 W5MAS8 PTHR10410:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 5 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 translation initiation factor#PC00224;translation factor#PC00223 PDGF signaling pathway#P00047>c-Jun#P01163 LEPOC|Ensembl=ENSLOCG00000013404.1|UniProtKB=W5N7B6 W5N7B6 PTHR23268:SF128 T-CELL RECEPTOR BETA CHAIN IMMUNOGLOBULIN V-SET DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000003546.1|UniProtKB=W5M766 W5M766 PTHR13392:SF14 ATAXIN 1 AXH DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;RNA binding#GO:0003723 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;head development#GO:0060322;nervous system development#GO:0007399;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;animal gross anatomical part developmental process#GO:0160108;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006832.1|UniProtKB=W5MIQ5 W5MIQ5 MORC3 PTHR23336:SF17 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone H3 reader activity#GO:0140006;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;defense response to other organism#GO:0098542;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;antiviral innate immune response#GO:0140374;defense response to virus#GO:0051607;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;immune system process#GO:0002376;response to virus#GO:0009615 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;PML body#GO:0016605;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003095.1|UniProtKB=W5M5J3 W5M5J3 PTHR13802:SF63 MUCIN 4-RELATED SUSHI DOMAIN-CONTAINING PROTEIN 2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000013535.1|UniProtKB=W5N7U1 W5N7U1 PTHR10763:SF26 CELL DIVISION CONTROL PROTEIN 6-RELATED DNA REPLICATION FACTOR CDC6 DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA replication origin binding#GO:0003688 DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 replication origin binding protein#PC00199 LEPOC|Ensembl=ENSLOCG00000015226.1|UniProtKB=W5NDM8 W5NDM8 PTHR19964:SF41 MULTIPLE PDZ DOMAIN PROTEIN LIGAND OF NUMB PROTEIN X 2-LIKE ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002325.1|UniProtKB=W5M2X8 W5M2X8 PTHR45788:SF4 SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;citrate transmembrane transporter activity#GO:0015137;active transmembrane transporter activity#GO:0022804 citrate transport#GO:0015746;tricarboxylic acid transport#GO:0006842;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011439.1|UniProtKB=W5N0A3 W5N0A3 PTHR46406:SF1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 ribosomal small subunit biogenesis#GO:0042274;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mitochondrial ribosome assembly#GO:0061668;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000013551.1|UniProtKB=W5N7V3 W5N7V3 PTHR11616:SF141 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT TAURINE TRANSPORTER solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865 cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000010064.1|UniProtKB=W5MVA2 W5MVA2 PTHR10649:SF17 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR 2 signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;molecular transducer activity#GO:0060089 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000003383.1|UniProtKB=W5M6J5 W5M6J5 PTHR45632:SF12 LD33804P KELCH-LIKE PROTEIN 15 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular response to stress#GO:0080135;regulation of DNA recombination#GO:0000018;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;regulation of double-strand break repair via homologous recombination#GO:0010569;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;negative regulation of metabolic process#GO:0009892;response to misfolded protein#GO:0051788;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of double-strand break repair via homologous recombination#GO:2000042;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;regulation of double-strand break repair#GO:2000779;cellular response to topologically incorrect protein#GO:0035967;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;primary metabolic process#GO:0044238;negative regulation of DNA recombination#GO:0045910;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;cellular response to misfolded protein#GO:0071218;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005009.1|UniProtKB=W5MCC0 W5MCC0 PTHR16770:SF4 PROTEIN RIPPLY-LIKE PROTEIN RIPPLY3 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;embryo development#GO:0009790;embryonic pattern specification#GO:0009880;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007927.1|UniProtKB=W5MMM1 W5MMM1 PTHR10218:SF376 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(O) SUBUNIT ALPHA hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity#GO:0003824;neuropeptide receptor binding#GO:0071855;pyrophosphatase activity#GO:0016462;G protein-coupled receptor binding#GO:0001664;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;G protein-coupled dopamine receptor signaling pathway#GO:0007212;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494 G-protein#PC00020;heterotrimeric G-protein#PC00117 LEPOC|Ensembl=ENSLOCG00000015979.1|UniProtKB=W5NGB6 W5NGB6 PTHR12202:SF0 ESF1 HOMOLOG ESF1 HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 LEPOC|Ensembl=ENSLOCG00000011961.1|UniProtKB=W5N252 W5N252 PTHR24099:SF13 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM9 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001442.1|UniProtKB=W5LZT7 W5LZT7 PTHR23003:SF52 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE_ARGININE-RICH SPLICING FACTOR 6 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000006449.1|UniProtKB=W5MHE5 W5MHE5 PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A LEPOC|Ensembl=ENSLOCG00000013357.1|UniProtKB=W5N759 W5N759 PTHR10202:SF18 PRESENILIN PRESENILIN-1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;monoatomic cation homeostasis#GO:0055080;cell surface receptor signaling pathway#GO:0007166;chemical homeostasis#GO:0048878;gene expression#GO:0010467;protein maturation#GO:0051604;membrane protein ectodomain proteolysis#GO:0006509;biosynthetic process#GO:0009058;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;protein metabolic process#GO:0019538;cell communication#GO:0007154;calcium ion homeostasis#GO:0055074;proteolysis#GO:0006508;inorganic ion homeostasis#GO:0098771;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;homeostatic process#GO:0042592;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;catalytic complex#GO:1902494 protease#PC00190;aspartic protease#PC00053 Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098;Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Notch signaling pathway#P00045>Presenilin#P01110;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129 LEPOC|Ensembl=ENSLOCG00000014996.1|UniProtKB=W5NCV7 W5NCV7 PTHR12974:SF30 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5D transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252 LEPOC|Ensembl=ENSLOCG00000017912.1|UniProtKB=W5NN06 W5NN06 PTHR47399:SF1 TRANSMEMBRANE PROTEIN 121B TRANSMEMBRANE PROTEIN 121B LEPOC|Ensembl=ENSLOCG00000016761.1|UniProtKB=W5NJA7 W5NJA7 PTHR23149:SF27 G PATCH DOMAIN CONTAINING PROTEIN PIN2_TERF1-INTERACTING TELOMERASE INHIBITOR 1 enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011109.1|UniProtKB=W5MZ36 W5MZ36 PTHR24332:SF16 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;embryonic pattern specification#GO:0009880;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;tube development#GO:0035295;embryo development#GO:0009790;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;cellular developmental process#GO:0048869;anterior/posterior axis specification#GO:0009948;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000008183.1|UniProtKB=W5MNI6 W5MNI6 PTHR10194:SF3 RAS GTPASE-ACTIVATING PROTEINS RASGAP-ACTIVATING-LIKE PROTEIN 1 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646;EGF receptor signaling pathway#P00018>GAP#P00546 LEPOC|Ensembl=ENSLOCG00000009639.1|UniProtKB=W5MTS0 W5MTS0 PTHR11723:SF6 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-4 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004167.1|UniProtKB=W5M9G9 W5M9G9 PTHR46097:SF4 G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP ARF GTPASE-ACTIVATING PROTEIN GIT2 molecular function activator activity#GO:0140677;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 multicellular organism development#GO:0007275;establishment of localization#GO:0051234;animal organ development#GO:0048513;vesicle-mediated transport in synapse#GO:0099003;regulation of small GTPase mediated signal transduction#GO:0051056;developmental process#GO:0032502;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;brain development#GO:0007420;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;head development#GO:0060322;nervous system development#GO:0007399;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;anatomical structure development#GO:0048856;cellular localization#GO:0051641;system development#GO:0048731;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000008300.1|UniProtKB=W5MNX2 W5MNX2 PTHR15237:SF1 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9A signaling#GO:0023052;cellular response to radiation#GO:0071478;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;response to ionizing radiation#GO:0010212;response to abiotic stimulus#GO:0009628;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cellular response to stress#GO:0033554;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;DNA replication checkpoint signaling#GO:0000076;cellular response to abiotic stimulus#GO:0071214;negative regulation of cell cycle#GO:0045786;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;mitotic DNA integrity checkpoint signaling#GO:0044774;response to radiation#GO:0009314;regulation of mitotic cell cycle#GO:0007346;DNA integrity checkpoint signaling#GO:0031570;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694 exodeoxyribonuclease#PC00098 LEPOC|Ensembl=ENSLOCG00000008364.1|UniProtKB=W5MP49 W5MP49 PTHR28578:SF2 MITOTIC-SPINDLE ORGANIZING PROTEIN 2A-RELATED MITOTIC-SPINDLE ORGANIZING PROTEIN 2A intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813 LEPOC|Ensembl=ENSLOCG00000007479.1|UniProtKB=W5ML23 W5ML23 PTHR23257:SF937 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 negative regulation of cell cycle process#GO:0010948;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of chromosome separation#GO:1905819;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of reproductive process#GO:2000241;positive regulation of response to stimulus#GO:0048584;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell cycle phase transition#GO:1901987;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of MAPK cascade#GO:0043408;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of chromosome segregation#GO:0051985;negative regulation of cell cycle#GO:0045786;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000012714.1|UniProtKB=W5N4T4 W5N4T4 PTHR15528:SF5 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR-RELATED PROTEIN 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;multicellular organismal-level homeostasis#GO:0048871;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000009679.1|UniProtKB=W5MTW4 W5MTW4 PTHR44969:SF2 CELL SURFACE A33 ANTIGEN GLYCOPROTEIN A33 (TRANSMEMBRANE), PARALOG A LEPOC|Ensembl=ENSLOCG00000003805.1|UniProtKB=W5M867 W5M867 PTHR24027:SF81 CADHERIN-23 CADHERIN-4 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;cell migration#GO:0016477;cell motility#GO:0048870 extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000003013.1|UniProtKB=W5M588 W5M588 PTHR31879:SF2 DET1- AND DDB1-ASSOCIATED PROTEIN 1 DET1- AND DDB1-ASSOCIATED PROTEIN 1 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of protein metabolic process#GO:0051247;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of ubiquitin-dependent protein catabolic process#GO:2000058 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 LEPOC|Ensembl=ENSLOCG00000015777.1|UniProtKB=W5NFL4 W5NFL4 PTHR14710:SF2 GEM-ASSOCIATED PROTEIN 6 GEM-ASSOCIATED PROTEIN 6 cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070 protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;cellular anatomical structure#GO:0110165;SMN complex#GO:0032797;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719 LEPOC|Ensembl=ENSLOCG00000004920.1|UniProtKB=W5MC10 W5MC10 PTHR11849:SF216 ETS TRANSCRIPTIONAL REGULATOR ERG DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000005023.1|UniProtKB=W5MCE0 W5MCE0 PTHR14087:SF7 THYMOCYTE NUCLEAR PROTEIN 1 THYMOCYTE NUCLEAR PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000017083.1|UniProtKB=W5NKF5 W5NKF5 PTHR43184:SF33 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B SUGAR PHOSPHATE EXCHANGER 3 xenobiotic transmembrane transporter activity#GO:0042910;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014698.1|UniProtKB=W5NBT5 W5NBT5 PTHR12673:SF79 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 1 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;filopodium assembly#GO:0046847;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000001237.1|UniProtKB=W5LZ45 W5LZ45 PTHR31212:SF4 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000002561.1|UniProtKB=W5M3Q0 W5M3Q0 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016548.1|UniProtKB=W5NII1 W5NII1 PTHR13119:SF22 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 6 DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription elongation#GO:0032784;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000000763.1|UniProtKB=W5LXI9 W5LXI9 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008677.1|UniProtKB=W5MQ90 W5MQ90 PTHR11071:SF11 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000010189.1|UniProtKB=W5MVS2 W5MVS2 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014175.1|UniProtKB=W5NA00 W5NA00 PTHR45793:SF22 HOMEOBOX PROTEIN CONE-ROD HOMEOBOX PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016875.1|UniProtKB=W5NJQ6 W5NJQ6 PTHR11472:SF41 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER ATP-DEPENDENT DNA HELICASE DDX11-RELATED ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678 cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle process#GO:0022402;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA helicase#PC00011;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000000768.1|UniProtKB=W5LXJ8 W5LXJ8 PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;extracellular region#GO:0005576 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000012315.1|UniProtKB=W5N3F1 W5N3F1 PTHR15592:SF11 MATRIN 3/NUCLEAR PROTEIN 220-RELATED RNA-BINDING PROTEIN 20 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000015021.1|UniProtKB=W5NCY5 W5NCY5 PTHR10279:SF6 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 2 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013691.1|UniProtKB=W5N8C1 W5N8C1 PTHR43150:SF3 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-3 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;ion channel regulator activity#GO:0099106;catalytic activity#GO:0003824;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;molecular function regulator activity#GO:0098772;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;binding#GO:0005488;transmembrane transporter binding#GO:0044325;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;protein binding#GO:0005515;channel regulator activity#GO:0016247 regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000004162.1|UniProtKB=W5M9B8 W5M9B8 PTHR24383:SF20 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002873.1|UniProtKB=W5M4S2 W5M4S2 PTHR10910:SF103 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;nucleic acid binding#GO:0003676;binding#GO:0005488;tRNA-specific adenosine deaminase activity#GO:0008251;double-stranded RNA binding#GO:0003725;hydrolase activity#GO:0016787;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;adenosine deaminase activity#GO:0004000 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;base conversion or substitution editing#GO:0016553;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;adenosine to inosine editing#GO:0006382;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003607.1|UniProtKB=W5M7C5 W5M7C5 PTHR24027:SF78 CADHERIN-23 CADHERIN-LIKE PROTEIN 26 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;cell migration#GO:0016477;cell motility#GO:0048870 extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000013743.1|UniProtKB=W5N8J0 W5N8J0 PTHR32546:SF7 G-PROTEIN COUPLED RECEPTOR 158-RELATED G PROTEIN-COUPLED RECEPTOR 179-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015459.1|UniProtKB=W5NEG7 W5NEG7 PTHR19302:SF70 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 6 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;cytoplasmic microtubule organization#GO:0031122;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000010967.1|UniProtKB=W5MYM3 W5MYM3 PTHR11782:SF35 ADENOSINE/GUANOSINE DIPHOSPHATASE NUCLEOSIDE DIPHOSPHATE PHOSPHATASE ENTPD5 pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 nucleoside diphosphate metabolic process#GO:0009132;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate catabolic process#GO:0046434;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181;nucleotide phosphatase#PC00173;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014593.1|UniProtKB=W5NBE9 W5NBE9 PTHR22674:SF6 NTPASE, KAP FAMILY P-LOOP DOMAIN-CONTAINING 1 NTPASE KAP FAMILY P-LOOP DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000005273.1|UniProtKB=W5MD93 W5MD93 PTHR24028:SF244 CADHERIN-87A PROTOCADHERIN-8-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000007598.1|UniProtKB=W5MLG2 W5MLG2 PTHR11267:SF91 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 LEPOC|Ensembl=ENSLOCG00000010241.1|UniProtKB=W5MVY0 W5MVY0 PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013241.1|UniProtKB=W5N6Q8 W5N6Q8 PTHR23003:SF15 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN MYELIN EXPRESSION FACTOR 2 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nuclear mRNA surveillance#GO:0071028 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000011145.1|UniProtKB=W5MZ91 W5MZ91 PTHR16082:SF2 AP-5 COMPLEX SUBUNIT MU-1 AP-5 COMPLEX SUBUNIT MU-1 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197 cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;membrane#GO:0016020;cytosol#GO:0005829;AP-type membrane coat adaptor complex#GO:0030119;lytic vacuole#GO:0000323;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;endosome#GO:0005768;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011461.1|UniProtKB=W5N0E1 W5N0E1 PTHR12616:SF16 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle fusion#GO:0006906;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;membrane fusion#GO:0061025;vesicle organization#GO:0016050;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;vesicle tethering complex#GO:0099023;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017585.1|UniProtKB=W5NM31 W5NM31 PTHR46675:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF182 E3 UBIQUITIN-PROTEIN LIGASE RNF182 LEPOC|Ensembl=ENSLOCG00000006106.1|UniProtKB=W5MG69 W5MG69 PTHR10381:SF11 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;serine-type peptidase activity#GO:0008236;binding#GO:0005488;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 protein-containing complex#GO:0032991;catalytic complex#GO:1902494 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000010715.1|UniProtKB=W5MXM0 W5MXM0 PTHR42899:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 LEPOC|Ensembl=ENSLOCG00000009863.1|UniProtKB=W5MUJ7 W5MUJ7 PTHR48169:SF3 DED DOMAIN-CONTAINING PROTEIN CASP8 AND FADD-LIKE APOPTOSIS REGULATOR negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of programmed cell death#GO:0043069;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of programmed cell death#GO:0043067;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057 LEPOC|Ensembl=ENSLOCG00000001721.1|UniProtKB=W5M0U2 W5M0U2 PTHR13503:SF3 NEGATIVE ELONGATION FACTOR COMPLEX MEMBER B NEGATIVE ELONGATION FACTOR B negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;stem cell differentiation#GO:0048863;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000003368.1|UniProtKB=W5M6H6 W5M6H6 PTHR47640:SF11 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED RNA-BINDING PROTEIN 42 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000010537.1|UniProtKB=W5MX03 W5MX03 PTHR13891:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cytochrome complex assembly#GO:0017004;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000017101.1|UniProtKB=W5NKI0 W5NKI0 PTHR45705:SF8 FI20236P1 STROMAL MEMBRANE-ASSOCIATED PROTEIN 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010566.1|UniProtKB=W5MX37 W5MX37 PTHR21141:SF119 60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN P2 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000015476.1|UniProtKB=W5NEI8 W5NEI8 PTHR24072:SF148 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOU purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924 actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;localization#GO:0051179;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;transport#GO:0006810;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein#PC00020;small GTPase#PC00208 Axon guidance mediated by netrin#P00009>cdc42#P00364;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515 LEPOC|Ensembl=ENSLOCG00000008813.1|UniProtKB=W5MQR5 W5MQR5 PTHR12096:SF0 NUCLEAR PROTEIN SKIP-RELATED SNW DOMAIN-CONTAINING PROTEIN 1 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000010205.1|UniProtKB=W5MVT2 W5MVT2 PTHR24366:SF51 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS MATRIX-REMODELING-ASSOCIATED PROTEIN 5 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000004353.1|UniProtKB=W5M9Z2 W5M9Z2 PTHR11955:SF59 FATTY ACID BINDING PROTEIN RETINOL-BINDING PROTEIN 2 lipid binding#GO:0008289;fatty acid binding#GO:0005504;organic acid binding#GO:0043177;binding#GO:0005488;carboxylic acid binding#GO:0031406;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908;macromolecule localization#GO:0033036;lipid transport#GO:0006869 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000015038.1|UniProtKB=W5NCZ8 W5NCZ8 PTHR11064:SF9 CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 LEPOC|Ensembl=ENSLOCG00000011194.1|UniProtKB=W5MZE0 W5MZE0 PTHR17530:SF2 PRO-THYROTROPIN-RELEASING HORMONE PRO-THYROTROPIN-RELEASING HORMONE signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708 peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585 LEPOC|Ensembl=ENSLOCG00000002810.1|UniProtKB=W5M4J7 W5M4J7 PTHR21680:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006791.1|UniProtKB=W5MIJ5 W5MIJ5 PTHR41693:SF3 HEME-BINDING PROTEIN 1 SI:CH211-76L23.4 LEPOC|Ensembl=ENSLOCG00000016255.1|UniProtKB=W5NHD5 W5NHD5 PTHR11537:SF172 VOLTAGE-GATED POTASSIUM CHANNEL VOLTAGE-GATED POTASSIUM CHANNEL KCNC2 channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215 cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;action potential#GO:0001508;metal ion transport#GO:0030001;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811 axon terminus#GO:0043679;neuron projection membrane#GO:0032589;voltage-gated potassium channel complex#GO:0008076;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuronal cell body#GO:0043025;neuron projection terminus#GO:0044306;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;cell leading edge#GO:0031252;neuron projection#GO:0043005;presynapse#GO:0098793;cell projection membrane#GO:0031253;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;postsynapse#GO:0098794;cell body#GO:0044297 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000014774.1|UniProtKB=W5NC32 W5NC32 PTHR10485:SF2 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-B transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005346.1|UniProtKB=W5MDJ1 W5MDJ1 PTHR46051:SF3 SH2 DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 5-PHOSPHATASE 1 regulation of lymphocyte activation#GO:0051249;regulation of cell activation#GO:0050865;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;regulation of bone resorption#GO:0045124;regulation of myeloid cell differentiation#GO:0045637;negative regulation of signaling#GO:0023057;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;negative regulation of signal transduction#GO:0009968;positive regulation of biological process#GO:0048518;regulation of B cell activation#GO:0050864;positive regulation of immune system process#GO:0002684;positive regulation of leukocyte activation#GO:0002696;positive regulation of cell differentiation#GO:0045597;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;negative regulation of multicellular organismal process#GO:0051241;regulation of tissue remodeling#GO:0034103;positive regulation of lymphocyte activation#GO:0051251;regulation of hemopoiesis#GO:1903706;regulation of immune response#GO:0050776;positive regulation of cell activation#GO:0050867;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of bone remodeling#GO:0046850;regulation of cell differentiation#GO:0045595;regulation of response to stimulus#GO:0048583;positive regulation of developmental process#GO:0051094;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000006566.1|UniProtKB=W5MHS3 W5MHS3 PTHR21737:SF6 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 SPLICING FACTOR CACTIN regulation of immune system process#GO:0002682;negative regulation of defense response#GO:0031348;RNA biosynthetic process#GO:0032774;regulation of response to biotic stimulus#GO:0002831;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;negative regulation of immune response#GO:0050777;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;negative regulation of response to stimulus#GO:0048585;negative regulation of immune system process#GO:0002683;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;regulation of innate immune response#GO:0045088;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;regulation of response to external stimulus#GO:0032101;gene expression#GO:0010467;negative regulation of response to external stimulus#GO:0032102;RNA processing#GO:0006396;negative regulation of innate immune response#GO:0045824;mRNA processing#GO:0006397;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008711.1|UniProtKB=W5MQE6 W5MQE6 PTHR10801:SF21 24-DEHYDROCHOLESTEROL REDUCTASE DELTA(24)-STEROL REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000003040.1|UniProtKB=W5M5C5 W5M5C5 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000018324.1|UniProtKB=W5NP66 W5NP66 PTHR16125:SF3 TRANSMEMBRANE PROTEIN 74 TRANSMEMBRANE PROTEIN 74 LEPOC|Ensembl=ENSLOCG00000002512.1|UniProtKB=W5M3J2 W5M3J2 PTHR10110:SF86 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 7 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009178.1|UniProtKB=W5MS58 W5MS58 PTHR45622:SF18 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC3-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005061.1|UniProtKB=W5MCI4 W5MCI4 PTHR28597:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT-ASSOCIATED REGULATORY PROTEIN VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT-ASSOCIATED REGULATORY PROTEIN binding#GO:0005488;transmembrane transporter binding#GO:0044325;protein binding#GO:0005515 regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016860.1|UniProtKB=W5NJN5 W5NJN5 MOCS3 PTHR10953:SF254 UBIQUITIN-ACTIVATING ENZYME E1 ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3 nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;catalytic activity, acting on a protein#GO:0140096;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782 RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;protein modification by small protein conjugation or removal#GO:0070647;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;protein modification by small protein conjugation#GO:0032446;tRNA wobble position uridine thiolation#GO:0002143;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;post-translational protein modification#GO:0043687;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013402.1|UniProtKB=W5N7B7 W5N7B7 PTHR10288:SF279 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 4 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000007163.1|UniProtKB=W5MJW9 W5MJW9 PTHR12792:SF3 EXTRA SPINDLE POLES 1-RELATED SEPARIN catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;chromosome separation#GO:0051304;meiotic chromosome segregation#GO:0045132;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fission#GO:0048285;nuclear division#GO:0000280;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402 intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;membraneless organelle#GO:0043228 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000011971.1|UniProtKB=W5N262 W5N262 PTHR46107:SF2 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000006700.1|UniProtKB=W5MI83 W5MI83 PTHR15902:SF2 NEURITIN-RELATED NEURITIN-LIKE PROTEIN multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell growth#GO:0016049;developmental growth#GO:0048589;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;neuron projection morphogenesis#GO:0048812;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;developmental cell growth#GO:0048588;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;neuron projection extension#GO:1990138;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000000356.1|UniProtKB=W5LW88 W5LW88 PTHR13822:SF7 ATP SYNTHASE DELTA/EPSILON CHAIN ATP SYNTHASE F(1) COMPLEX SUBUNIT DELTA, MITOCHONDRIAL channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleoside phosphate biosynthetic process#GO:1901293;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate biosynthetic process#GO:0090407;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000013278.1|UniProtKB=W5N6V2 W5N6V2 PTHR19957:SF285 SYNTAXIN SYNTAXIN-8 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 cellular component organization#GO:0016043;vesicle fusion#GO:0006906;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;SNARE complex#GO:0031201;cytoplasm#GO:0005737 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000009917.1|UniProtKB=W5MUR8 W5MUR8 PTHR15545:SF10 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 E3 UBIQUITIN-PROTEIN LIGASE PDZRN3-B-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 metabolic process#GO:0008152;neuromuscular junction development#GO:0007528;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;synapse organization#GO:0050808;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular component organization#GO:0016043;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cell junction organization#GO:0034330 LEPOC|Ensembl=ENSLOCG00000001390.1|UniProtKB=W5LZM1 W5LZM1 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 antigen binding#GO:0003823;binding#GO:0005488 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000006769.1|UniProtKB=W5MII6 W5MII6 PTHR10037:SF23 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 8 SUBUNIT ALPHA channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;system process#GO:0003008;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;nervous system process#GO:0050877;sensory perception#GO:0007600;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;sensory perception of pain#GO:0019233;sodium ion transport#GO:0006814;action potential#GO:0001508;membrane depolarization#GO:0051899;metal ion transport#GO:0030001 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cation channel complex#GO:0034703;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;axon#GO:0030424;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000007485.1|UniProtKB=W5ML28 W5ML28 PTHR11471:SF27 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;regulation of apoptotic signaling pathway#GO:2001233;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Apoptosis signaling pathway#P00006>TRAIL#P00263 LEPOC|Ensembl=ENSLOCG00000011788.1|UniProtKB=W5N1J0 W5N1J0 PTHR11177:SF405 CHITINASE ACIDIC MAMMALIAN CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030;macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000008708.1|UniProtKB=W5MQE0 W5MQE0 PTHR44819:SF1 V-TYPE IMMUNOGLOBULIN DOMAIN-CONTAINING SUPPRESSOR OF T-CELL ACTIVATION V-TYPE IMMUNOGLOBULIN DOMAIN-CONTAINING SUPPRESSOR OF T-CELL ACTIVATION regulation of T cell activation#GO:0050863;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of cell activation#GO:0050866;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of lymphocyte activation#GO:0051249;negative regulation of leukocyte cell-cell adhesion#GO:1903038;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;negative regulation of T cell activation#GO:0050868 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011685.1|UniProtKB=W5N151 W5N151 PTHR24329:SF578 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARISTALESS-LIKE 3 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000005773.1|UniProtKB=W5MF16 W5MF16 PTHR11675:SF130 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 5 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000006585.1|UniProtKB=W5MHU6 W5MHU6 PTHR23042:SF50 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 Hypoxia response via HIF activation#P00030>HIF-1beta#P00820 LEPOC|Ensembl=ENSLOCG00000007320.1|UniProtKB=W5MKF8 W5MKF8 PTHR10134:SF50 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122 oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex III#GO:0045275 LEPOC|Ensembl=ENSLOCG00000013128.1|UniProtKB=W5N6C3 W5N6C3 PTHR24092:SF80 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IM-RELATED intramembrane lipid carrier activity#GO:0140303;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215 cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;biological regulation#GO:0065007;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000017264.1|UniProtKB=W5NL45 W5NL45 PTHR11685:SF479 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF217 enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011967.1|UniProtKB=W5N254 W5N254 PTHR22446:SF3 M-PHASE-SPECIFIC PLK1-INTERACTING PROTEIN M-PHASE-SPECIFIC PLK1-INTERACTING PROTEIN cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013074.1|UniProtKB=W5N644 W5N644 PTHR24366:SF158 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS PLATELET GLYCOPROTEIN IB ALPHA CHAIN immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000015469.1|UniProtKB=W5NEI0 W5NEI0 PTHR18887:SF2 GOLGI-ASSOCIATED PROTEIN GCP360-RELATED GOLGIN SUBFAMILY B MEMBER 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular anatomical structure#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000003683.1|UniProtKB=W5M7L3 W5M7L3 PTHR12630:SF6 N-LINKED OLIGOSACCHARIDE PROCESSING N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNIT GAMMA metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000008461.1|UniProtKB=W5MPI6 W5MPI6 PTHR45876:SF1 FI04035P RHO GTPASE-ACTIVATING PROTEIN 39 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000011798.1|UniProtKB=W5N1J6 W5N1J6 PTHR45946:SF3 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-A1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009495.1|UniProtKB=W5MT88 W5MT88 PTHR10127:SF791 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000004680.1|UniProtKB=W5MB52 W5MB52 PTHR48083:SF20 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carnitine metabolic process#GO:0009437;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000015289.1|UniProtKB=W5NDV2 W5NDV2 PTHR12837:SF9 POLY ADP-RIBOSE GLYCOHYDROLASE POLY(ADP-RIBOSE) GLYCOHYDROLASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;regulation of DNA metabolic process#GO:0051052;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;regulation of cellular response to stress#GO:0080135;ribonucleotide metabolic process#GO:0009259;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;organophosphate metabolic process#GO:0019637;regulation of primary metabolic process#GO:0080090;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000016774.1|UniProtKB=W5NJC3 W5NJC3 PTHR23339:SF93 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009779.1|UniProtKB=W5MUA0 W5MUA0 PTHR24278:SF28 COAGULATION FACTOR COAGULATION FACTOR X peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 Blood coagulation#P00011>FXa#P00445;Blood coagulation#P00011>FX#P00430 LEPOC|Ensembl=ENSLOCG00000015991.1|UniProtKB=W5NGD2 W5NGD2 PTHR34094:SF1 FAMILY NOT NAMED PROTEIN FAM185A LEPOC|Ensembl=ENSLOCG00000015843.1|UniProtKB=W5NFU4 W5NFU4 PTHR11062:SF97 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-1 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375;glucuronosyltransferase activity#GO:0015020;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000018122.1|UniProtKB=W5NNL4 W5NNL4 PTHR24388:SF109 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 221-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000010269.1|UniProtKB=W5MW16 W5MW16 PTHR12484:SF4 B-LYMPHOCYTE ANTIGEN-RELATED A-KINASE ANCHOR PROTEIN 17A LEPOC|Ensembl=ENSLOCG00000010060.1|UniProtKB=W5MV99 W5MV99 PTHR44269:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000005086.1|UniProtKB=W5MCL5 W5MCL5 PTHR46272:SF4 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 LEPOC|Ensembl=ENSLOCG00000008863.1|UniProtKB=W5MQX9 W5MQX9 PTHR46144:SF2 ZINC FINGER PROTEIN 385B-LIKE ZINC FINGER PROTEIN ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000008835.1|UniProtKB=W5MQX3 W5MQX3 PTHR15036:SF57 PIKACHURIN-LIKE PROTEIN NEUREXIN-3 signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor binding#GO:0005102 postsynaptic density organization#GO:0097106;nervous system process#GO:0050877;animal gross anatomical part developmental process#GO:0160108;excitatory synapse assembly#GO:1904861;signaling#GO:0023052;response to stimulus#GO:0050896;synapse assembly#GO:0007416;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;nervous system development#GO:0007399;cellular component assembly#GO:0022607;signal transduction#GO:0007165;cellular process#GO:0009987;postsynaptic density assembly#GO:0097107;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;postsynaptic specialization organization#GO:0099084;system development#GO:0048731;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;synapse organization#GO:0050808;organelle assembly#GO:0070925;protein localization to cell junction#GO:1902414;cognition#GO:0050890;postsynapse organization#GO:0099173;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;cellular response to stimulus#GO:0051716;system process#GO:0003008;intracellular protein localization#GO:0008104;developmental process#GO:0032502;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036 presynaptic active zone membrane#GO:0048787;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;synapse#GO:0045202;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;cell junction#GO:0030054 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011922.1|UniProtKB=W5N204 W5N204 PTHR11142:SF5 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE(38_39) SYNTHASE catalytic activity, acting on a nucleic acid#GO:0140640;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;tRNA modification#GO:0006400;pseudouridine synthesis#GO:0001522;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000005483.1|UniProtKB=W5ME06 W5ME06 PTHR24327:SF89 HOMEOBOX PROTEIN BRAIN-SPECIFIC HOMEOBOX PROTEIN HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;stem cell population maintenance#GO:0019827;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;maintenance of cell number#GO:0098727;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000009631.1|UniProtKB=W5MTR0 W5MTR0 PTHR46436:SF1 CENTROSOMAL PROTEIN OF 76 KDA CENTROSOMAL PROTEIN OF 76 KDA regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of microtubule-based process#GO:0032886 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000007102.1|UniProtKB=W5MJR0 W5MJR0 PTHR23182:SF3 BREAKPOINT CLUSTER REGION PROTEIN BCR BREAKPOINT CLUSTER REGION PROTEIN molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 cell junction#GO:0030054;postsynaptic density#GO:0014069;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane#GO:0005886;postsynapse#GO:0098794;membrane#GO:0016020;cell periphery#GO:0071944 G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000007996.1|UniProtKB=W5MMV1 W5MMV1 PTHR10196:SF68 SUGAR KINASE GLYCEROL KINASE 5 phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;organophosphate biosynthetic process#GO:0090407 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 carbohydrate kinase#PC00065;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000009231.1|UniProtKB=W5MSA1 W5MSA1 PTHR22872:SF4 BTK-BINDING PROTEIN-RELATED RCC1 AND BTB DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000004442.1|UniProtKB=W5MAA0 W5MAA0 PTHR10721:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015666.1|UniProtKB=W5NF76 W5NF76 PTHR24356:SF181 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C THETA TYPE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Apoptosis signaling pathway#P00006>PKCs#P00318;FGF signaling pathway#P00021>PKC#P00648;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Wnt signaling pathway#P00057>Protein Kinase C#P01458;CCKR signaling map#P06959>PKCtheta#P07140;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;T cell activation#P00053>PKC-theta#P01318;Endothelin signaling pathway#P00019>PKC#P00568;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;Gonadotropin-releasing hormone receptor pathway#P06664>PKCe/theta#P06798;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219 LEPOC|Ensembl=ENSLOCG00000001488.1|UniProtKB=W5M017 W5M017 PTHR11437:SF67 RIBONUCLEASE RNASE 2-RELATED catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 defense response to Gram-positive bacterium#GO:0050830;anatomical structure morphogenesis#GO:0009653;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;blood vessel morphogenesis#GO:0048514;response to external biotic stimulus#GO:0043207;defense response to Gram-negative bacterium#GO:0050829;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;circulatory system development#GO:0072359;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;tube development#GO:0035295;response to other organism#GO:0051707;multicellular organismal process#GO:0032501;developmental process#GO:0032502;response to external stimulus#GO:0009605;vasculature development#GO:0001944;defense response#GO:0006952;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275 RNA metabolism protein#PC00031;endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000008993.1|UniProtKB=W5MRE7 W5MRE7 PTHR11113:SF14 N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE deacylase activity#GO:0160215;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;hydrolase activity#GO:0016787 carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar catabolic process#GO:0046348;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;deacetylase#PC00087 N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036 LEPOC|Ensembl=ENSLOCG00000016594.1|UniProtKB=W5NIQ4 W5NIQ4 PTHR46399:SF7 B30.2/SPRY DOMAIN-CONTAINING PROTEIN RYANODINE RECEPTOR 2 gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;striated muscle contraction#GO:0006941;metal ion transport#GO:0030001;muscle system process#GO:0003012;calcium ion transmembrane transport#GO:0070588;calcium ion transport#GO:0006816;system process#GO:0003008;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;transport#GO:0006810;muscle contraction#GO:0006936;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;sarcoplasmic reticulum membrane#GO:0033017;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;sarcoplasmic reticulum#GO:0016529;bounding membrane of organelle#GO:0098588;sarcomere#GO:0030017;transporter complex#GO:1990351;cation channel complex#GO:0034703;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;calcium channel complex#GO:0034704;supramolecular fiber#GO:0099512;organelle subcompartment#GO:0031984;myofibril#GO:0030016;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;endomembrane system#GO:0012505;cell periphery#GO:0071944;Z disc#GO:0030018;membrane#GO:0016020;organelle membrane#GO:0031090;sarcolemma#GO:0042383;membraneless organelle#GO:0043228;I band#GO:0031674;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528 CCKR signaling map#P06959>RYR1/2/3#P07088;Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441 LEPOC|Ensembl=ENSLOCG00000012275.1|UniProtKB=W5N3A5 W5N3A5 PTHR23420:SF3 ADENOSYLHOMOCYSTEINASE S-ADENOSYLHOMOCYSTEINE HYDROLASE-LIKE PROTEIN 1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;carbohydrate derivative metabolic process#GO:1901135;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;purine-containing compound metabolic process#GO:0072521 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011152.1|UniProtKB=W5MZ90 W5MZ90 PTHR10342:SF68 ARYLSULFATASE ARYLSULFATASE I catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 LEPOC|Ensembl=ENSLOCG00000010213.1|UniProtKB=W5MVU5 W5MVU5 PTHR11515:SF14 GLYCOPROTEIN HORMONE BETA CHAIN GLYCOPROTEIN HORMONE BETA-5 hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000012918.1|UniProtKB=W5N5J7 W5N5J7 PTHR24329:SF301 HOMEOBOX PROTEIN ARISTALESS PAIRED MESODERM HOMEOBOX PROTEIN 2B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000012949.1|UniProtKB=W5N5P0 W5N5P0 PTHR46753:SF2 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;establishment of organelle localization#GO:0051656;positive regulation of macroautophagy#GO:0016239;positive regulation of cellular component organization#GO:0051130;microtubule-based transport#GO:0099111;positive regulation of metabolic process#GO:0009893;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;positive regulation of autophagy#GO:0010508;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;regulation of macroautophagy#GO:0016241;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;organelle localization#GO:0051640;localization#GO:0051179;regulation of metabolic process#GO:0019222;vesicle localization#GO:0051648;positive regulation of cellular process#GO:0048522;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;regulation of autophagosome maturation#GO:1901096;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;positive regulation of catabolic process#GO:0009896;vesicle cytoskeletal trafficking#GO:0099518;regulation of catabolic process#GO:0009894 endomembrane system#GO:0012505;late endosome#GO:0005770;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;autophagosome#GO:0005776;intracellular organelle#GO:0043229;endosome#GO:0005768 LEPOC|Ensembl=ENSLOCG00000008412.1|UniProtKB=W5MPB5 W5MPB5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016429.1|UniProtKB=W5NI33 W5NI33 PTHR45832:SF4 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED SERINE_THREONINE-PROTEIN KINASE PAK 5 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000016216.1|UniProtKB=W5NH84 W5NH84 PTHR23326:SF35 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2 negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;CCR4-NOT complex#GO:0030014 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010134.1|UniProtKB=W5MVJ5 W5MVJ5 PTHR21274:SF2 MECKELIN MECKELIN cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;ciliary transition zone#GO:0035869;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000013639.1|UniProtKB=W5N878 W5N878 PTHR24356:SF193 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C ALPHA TYPE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>PKCs#P00318;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;CCKR signaling map#P06959>PKCalpha#P07095;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PKC#P05942;PDGF signaling pathway#P00047>PKC#P01150;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs(3)#P06850;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Angiogenesis#P00005>PKC#P00219;VEGF signaling pathway#P00056>PKC#P01425;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Endothelin signaling pathway#P00019>PKC#P00568 LEPOC|Ensembl=ENSLOCG00000008968.1|UniProtKB=W5MRB6 W5MRB6 PTHR23320:SF128 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A-LIKE transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006512.1|UniProtKB=W5MHL6 W5MHL6 PTHR23220:SF78 INTEGRIN ALPHA INTEGRIN ALPHA-4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;plasma membrane#GO:0005886 integrin#PC00126;cell adhesion molecule#PC00069 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000000077.1|UniProtKB=W5LVD1 W5LVD1 PTHR24418:SF23 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRMS catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;signaling receptor binding#GO:0005102;binding#GO:0005488;non-membrane spanning protein tyrosine kinase activity#GO:0004715 enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000008368.1|UniProtKB=W5MP56 W5MP56 PTHR22950:SF708 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000006979.1|UniProtKB=W5MJ86 W5MJ86 PTHR13142:SF1 INNER CENTROMERE PROTEIN INNER CENTROMERE PROTEIN membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;midbody#GO:0030496;chromosome#GO:0005694;kinetochore#GO:0000776;membraneless organelle#GO:0043228;spindle#GO:0005819;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000009432.1|UniProtKB=W5MT02 W5MT02 PTHR24255:SF41 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED MANNAN-BINDING LECTIN SERINE PROTEASE 1 ISOFORM X1 serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000010845.1|UniProtKB=W5MY29 W5MY29 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010779.1|UniProtKB=W5MXV1 W5MXV1 PTHR46538:SF2 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000005234.1|UniProtKB=W5MD48 W5MD48 PTHR10579:SF172 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000004181.1|UniProtKB=W5M9J1 W5M9J1 PTHR13723:SF41 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 8 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000006864.1|UniProtKB=W5MIU3 W5MIU3 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011951.1|UniProtKB=W5N237 W5N237 PTHR13989:SF58 REPLICATION PROTEIN A-RELATED CST COMPLEX SUBUNIT STN1 telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;telomere organization#GO:0032200;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;cellular process#GO:0009987;telomere maintenance via telomere lengthening#GO:0010833;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781;nucleus#GO:0005634;nuclear telomere cap complex#GO:0000783;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000010891.1|UniProtKB=W5MY98 W5MY98 PTHR13533:SF53 N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE N-ACETYLNEURAMINATE (7)9-O-ACETYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 acetyltransferase#PC00038;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007367.1|UniProtKB=W5MKM2 W5MKM2 PTHR23339:SF130 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE 4A3B-RELATED phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000009256.1|UniProtKB=W5MSD0 W5MSD0 PTHR10206:SF0 CATHELICIDIN CATHELICIDIN-6-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 antimicrobial response protein#PC00051 LEPOC|Ensembl=ENSLOCG00000011540.1|UniProtKB=W5N0L8 W5N0L8 PTHR33690:SF2 DUF4605 DOMAIN-CONTAINING PROTEIN PROTEIN FAM241B intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000011987.1|UniProtKB=W5N283 W5N283 PTHR11158:SF33 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING 1 lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000009749.1|UniProtKB=W5MU54 W5MU54 PTHR44444:SF1 PROTEIN SEL-1 HOMOLOG 3 PROTEIN SEL-1 HOMOLOG 3 LEPOC|Ensembl=ENSLOCG00000010982.1|UniProtKB=W5MYL4 W5MYL4 PTHR12442:SF34 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 1 binding#GO:0005488;protein binding#GO:0005515 localization#GO:0051179;transport along microtubule#GO:0010970;cellular localization#GO:0051641;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;microtubule-based transport#GO:0099111;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000007015.1|UniProtKB=W5MJE0 W5MJE0 PTHR14009:SF8 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804 monoatomic ion transmembrane transport#GO:0034220;mitochondrion organization#GO:0007005;monoatomic cation transmembrane transport#GO:0098655;mitochondrial calcium ion transmembrane transport#GO:0006851;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;calcium ion transport#GO:0006816;transport#GO:0006810;metal ion transport#GO:0030001;cellular component organization#GO:0016043;calcium ion transmembrane transport#GO:0070588;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014628.1|UniProtKB=W5NBK2 W5NBK2 PTHR24299:SF8 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1A1 monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491 response to chemical#GO:0042221;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;cellular response to xenobiotic stimulus#GO:0071466;lipid catabolic process#GO:0016042;cellular process#GO:0009987;secondary metabolic process#GO:0019748;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;response to stimulus#GO:0050896;catabolic process#GO:0009056;xenobiotic metabolic process#GO:0006805;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008;steroid catabolic process#GO:0006706;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000016831.1|UniProtKB=W5NJJ6 W5NJJ6 PTHR23167:SF51 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL3 oxidoreductase activity#GO:0016491;cytoskeletal protein binding#GO:0008092;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;actin filament depolymerization#GO:0030042;cellular component organization#GO:0016043;organelle organization#GO:0006996;protein depolymerization#GO:0051261;cytoskeleton organization#GO:0007010;protein-containing complex disassembly#GO:0032984;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004558.1|UniProtKB=W5MAR3 W5MAR3 PTHR24198:SF65 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 4 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011092.1|UniProtKB=W5MZ22 W5MZ22 PTHR10527:SF21 IMPORTIN BETA TRANSPORTIN-1 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005844.1|UniProtKB=W5MF95 W5MF95 PTHR10342:SF276 ARYLSULFATASE ARYLSULFATASE B catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 LEPOC|Ensembl=ENSLOCG00000009078.1|UniProtKB=W5MRQ7 W5MRQ7 PTHR46145:SF1 HEPARANASE INACTIVE HEPARANASE-2 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000003149.1|UniProtKB=W5M5Q5 W5M5Q5 PTHR28434:SF1 PROTEIN C3ORF33 MITOCHONDRIAL INNER MEMBRANE SUBDOMAIN ORGANIZER 1 LEPOC|Ensembl=ENSLOCG00000001610.1|UniProtKB=W5M0P5 W5M0P5 PTHR11412:SF150 MACROGLOBULIN / COMPLEMENT ALPHA-2 MACROGLOBULIN-LIKE PROTEIN-RELATED enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000002170.1|UniProtKB=W5M2B9 W5M2B9 PTHR43313:SF62 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 ISOFORM X1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;biological regulation#GO:0065007;hormone biosynthetic process#GO:0042446;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;steroid biosynthetic process#GO:0006694;regulation of biological quality#GO:0065008;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000018361.1|UniProtKB=W5NPA3 W5NPA3 PTHR24247:SF193 5-HYDROXYTRYPTAMINE RECEPTOR BETA-2 ADRENERGIC RECEPTOR ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;cation binding#GO:0043169;serotonin binding#GO:0051378;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;heterocyclic compound binding#GO:1901363;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165 dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010120.1|UniProtKB=W5MVH6 W5MVH6 TRMT5 PTHR23245:SF44 TRNA METHYLTRANSFERASE TRNA (GUANINE(37)-N(1))-METHYLTRANSFERASE RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;mitochondrial RNA modification#GO:1900864;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;mitochondrial RNA metabolic process#GO:0000959;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;mitochondrial gene expression#GO:0140053;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA methylation#GO:0030488;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000015849.1|UniProtKB=W5NFV3 W5NFV3 PTHR21831:SF2 MICROTUBULE-ASSOCIATED PROTEIN 10 MICROTUBULE-ASSOCIATED PROTEIN 10 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;regulation of cell division#GO:0051302;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;positive regulation of cellular process#GO:0048522;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;biological regulation#GO:0065007;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;regulation of cell cycle#GO:0051726;cytoplasmic microtubule organization#GO:0031122;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;regulation of cytokinesis#GO:0032465;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;positive regulation of cell cycle#GO:0045787;spindle elongation#GO:0051231;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;mitotic spindle#GO:0072686;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle pole#GO:0000922;cytoplasmic microtubule#GO:0005881;midbody#GO:0030496;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;microtubule#GO:0005874;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001009.1|UniProtKB=W5LYD0 W5LYD0 PTHR12214:SF5 GC-RICH SEQUENCE DNA-BINDING FACTOR GCF C-TERMINAL DOMAIN-CONTAINING PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000002144.1|UniProtKB=W5M2B2 W5M2B2 PTHR11347:SF184 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 9A ISOFORM X1-RELATED cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;negative regulation of cellular process#GO:0048523;nucleotide catabolic process#GO:0009166;regulation of response to stimulus#GO:0048583;cyclic nucleotide metabolic process#GO:0009187;regulation of cellular process#GO:0050794;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;negative regulation of signal transduction#GO:0009968;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cyclic purine nucleotide metabolic process#GO:0052652;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;negative regulation of biological process#GO:0048519;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;nucleotide metabolic process#GO:0009117;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;ribonucleotide metabolic process#GO:0009259;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000003666.1|UniProtKB=W5M7J6 W5M7J6 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;sensory organ development#GO:0007423;system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513;sensory system development#GO:0048880;multicellular organismal process#GO:0032501 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006694.1|UniProtKB=W5MI78 W5MI78 PTHR19282:SF214 TETRASPANIN CD81 ANTIGEN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007064.1|UniProtKB=W5MJJ4 W5MJJ4 PTHR28638:SF1 CELL CYCLE PROGRESSION PROTEIN 1 PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR-INTERACTING PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000007118.1|UniProtKB=W5MJQ8 W5MJQ8 PTHR45874:SF5 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-D10 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000011910.1|UniProtKB=W5N211 W5N211 PTHR45615:SF44 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-13 binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;actin binding#GO:0003779;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 multicellular organismal process#GO:0032501;system process#GO:0003008;muscle contraction#GO:0006936;muscle system process#GO:0003012 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000006460.1|UniProtKB=W5MHE4 W5MHE4 PTHR22812:SF85 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 5 chromatin binding#GO:0003682;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775 LEPOC|Ensembl=ENSLOCG00000000815.1|UniProtKB=W5LXQ3 W5LXQ3 PTHR15185:SF3 BCL9 B-CELL CLL_LYMPHOMA 9-LIKE PROTEIN beta-catenin binding#GO:0008013;protein binding#GO:0005515;binding#GO:0005488 positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of RNA biosynthetic process#GO:1902680;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000003088.1|UniProtKB=W5M5I8 W5M5I8 PTHR23319:SF1 GRAM DOMAIN CONTAINING 1B, ISOFORM E PROTEIN ASTER-C sterol transfer activity#GO:0120015;transporter activity#GO:0005215;steroid binding#GO:0005496;cholesterol transfer activity#GO:0120020;alcohol binding#GO:0043178;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094;lipid transfer activity#GO:0120013;cholesterol binding#GO:0015485;lipid binding#GO:0008289 establishment of localization#GO:0051234;sterol transport#GO:0015918;cellular localization#GO:0051641;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;intracellular transport#GO:0046907;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;intracellular sterol transport#GO:0032366;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle membrane contact site#GO:0044232 LEPOC|Ensembl=ENSLOCG00000010174.1|UniProtKB=W5MVP6 W5MVP6 PTHR46129:SF4 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN-16 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000012448.1|UniProtKB=W5N3W3 W5N3W3 PTHR13820:SF10 SYNUCLEIN GAMMA-SYNUCLEIN cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;copper ion binding#GO:0005507 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chemical synaptic transmission#GO:0007268;synaptic vesicle endocytosis#GO:0048488;signaling#GO:0023052;cell junction organization#GO:0034330;endocytosis#GO:0006897;anterograde trans-synaptic signaling#GO:0098916;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;cellular localization#GO:0051641;cell communication#GO:0007154;localization#GO:0051179 axon#GO:0030424;intracellular anatomical structure#GO:0005622;cell body#GO:0044297;synapse#GO:0045202;cellular anatomical structure#GO:0110165;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;neuron projection terminus#GO:0044306;cell junction#GO:0030054;axon terminus#GO:0043679;presynapse#GO:0098793;neuron projection#GO:0043005;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 Parkinson disease#P00049>gamma-Synuclein#P01231 LEPOC|Ensembl=ENSLOCG00000017267.1|UniProtKB=W5NL50 W5NL50 PTHR11845:SF13 5'-DEOXYNUCLEOTIDASE HDDC2 5'-DEOXYNUCLEOTIDASE HDDC2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016191.1|UniProtKB=W5NH48 W5NH48 PTHR15217:SF0 WILMS' TUMOR 1-ASSOCIATING PROTEIN PRE-MRNA-SPLICING REGULATOR WTAP enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA metabolic process#GO:1903311;mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000014087.1|UniProtKB=W5N9P9 W5N9P9 PTHR12316:SF19 NINJURIN-RELATED NINJURIN-1 cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 response to stimulus#GO:0050896;cellular process#GO:0009987;cell death#GO:0008219;response to stress#GO:0006950;programmed cell death#GO:0012501;defense response#GO:0006952;cell adhesion#GO:0007155;inflammatory response#GO:0006954 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009085.1|UniProtKB=W5MRT7 W5MRT7 PTHR46026:SF3 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 7 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;lamellipodium assembly#GO:0030032;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;cell leading edge#GO:0031252 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006945.1|UniProtKB=W5MJ41 W5MJ41 PTHR12015:SF190 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE-RELATED cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000009517.1|UniProtKB=W5MTC6 W5MTC6 PTHR44981:SF3 PERICENTRIN-LIKE PROTEIN, ISOFORM F PERICENTRIN mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 LEPOC|Ensembl=ENSLOCG00000017670.1|UniProtKB=W5NMB6 W5NMB6 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011747.1|UniProtKB=W5N1E4 W5N1E4 PTHR22812:SF162 CHROMOBOX PROTEIN CHROMOBOX 3 chromatin binding#GO:0003682;binding#GO:0005488 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000013021.1|UniProtKB=W5N5Y2 W5N5Y2 PTHR24173:SF33 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 2 catabolic process#GO:0009056;circulatory system development#GO:0072359;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;system development#GO:0048731;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;animal gross anatomical part developmental process#GO:0160108;proteasomal protein catabolic process#GO:0010498;multicellular organismal process#GO:0032501;heart development#GO:0007507;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;animal organ development#GO:0048513;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015452.1|UniProtKB=W5NEF9 W5NEF9 PTHR28576:SF2 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000006881.1|UniProtKB=W5MIW2 W5MIW2 PTHR12015:SF213 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE-RELATED cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000001768.1|UniProtKB=W5M0Z9 W5M0Z9 PTHR18934:SF99 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX37-RELATED helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000015544.1|UniProtKB=W5NES6 W5NES6 IMPDH PTHR11911:SF74 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 LEPOC|Ensembl=ENSLOCG00000013703.1|UniProtKB=W5N8F3 W5N8F3 PTHR13954:SF17 IRE1-RELATED SERINE_THREONINE-PROTEIN KINASE_ENDORIBONUCLEASE IRE1 protein kinase activity#GO:0004672;nuclease activity#GO:0004518;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell communication#GO:0007154;response to unfolded protein#GO:0006986;intrinsic apoptotic signaling pathway#GO:0097193;intracellular signal transduction#GO:0035556;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;cell death#GO:0008219;apoptotic signaling pathway#GO:0097190;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 tyrosine protein kinase receptor#PC00233;transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110;Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144 LEPOC|Ensembl=ENSLOCG00000014239.1|UniProtKB=W5NA75 W5NA75 PTHR12991:SF10 NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4 GATOR1 COMPLEX PROTEIN NPRL2 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;response to starvation#GO:0042594;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;cellular response to amino acid starvation#GO:0034198;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;response to nutrient levels#GO:0031667;response to stress#GO:0006950;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;regulation of TORC1 signaling#GO:1903432;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;negative regulation of TORC1 signaling#GO:1904262;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583 intracellular organelle#GO:0043229;Seh1-associated complex#GO:0035859;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000004506.1|UniProtKB=W5MAI5 W5MAI5 PTHR45818:SF4 PROTEIN VAV GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 positive regulation of cellular process#GO:0048522;immune response-regulating cell surface receptor signaling pathway#GO:0002768;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;intracellular signaling cassette#GO:0141124;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;signaling#GO:0023052;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 B cell activation#P00010>vav#P00368;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169 LEPOC|Ensembl=ENSLOCG00000011674.1|UniProtKB=W5N136 W5N136 PTHR17103:SF15 NEUREXOPHILIN NEUREXOPHILIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;GABA-ergic synapse#GO:0098982 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014719.1|UniProtKB=W5NBW7 W5NBW7 PTHR46842:SF1 TRANSMEMBRANE PROTEIN 266 TRANSMEMBRANE PROTEIN 266 LEPOC|Ensembl=ENSLOCG00000015212.1|UniProtKB=W5NDL0 W5NDL0 PTHR12186:SF3 SIKE FAMILY MEMBER FGFR1 ONCOGENE PARTNER 2 response to stimulus#GO:0050896;response to stress#GO:0006950;response to wounding#GO:0009611 LEPOC|Ensembl=ENSLOCG00000006186.1|UniProtKB=W5MGG9 W5MGG9 PTHR10190:SF7 EYES ABSENT PROTEIN PHOSPHATASE EYA2 phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;positive regulation of DNA metabolic process#GO:0051054;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA repair#GO:0045739;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of response to stress#GO:0080134;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000014050.1|UniProtKB=W5N9K8 W5N9K8 PTHR44019:SF17 WD REPEAT-CONTAINING PROTEIN 55 F-BOX_WD REPEAT-CONTAINING PROTEIN 12 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000018104.1|UniProtKB=W5NNJ6 W5NNJ6 PTHR24070:SF290 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE, FAMILY 10, MEMBER A hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000007381.1|UniProtKB=W5MKP2 W5MKP2 PTHR12661:SF5 PETER PAN-RELATED SUPPRESSOR OF SWI4 1 HOMOLOG RNA binding#GO:0003723;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654 preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005000.1|UniProtKB=W5MCB2 W5MCB2 PTHR18952:SF124 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 7 catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000015682.1|UniProtKB=W5NF98 W5NF98 PTHR18939:SF4 RIBOSOME BINDING PROTEIN-1 RIBOSOME-BINDING PROTEIN 1 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015135.1|UniProtKB=W5NDC0 W5NDC0 PTHR23405:SF4 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED PROTEIN MAK16 HOMOLOG maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000005347.1|UniProtKB=W5MDJ3 W5MDJ3 PTHR13412:SF0 T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG T-CELL IMMUNOMODULATORY PROTEIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000013505.1|UniProtKB=W5N7P0 W5N7P0 PTHR12619:SF2 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX7 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000018198.1|UniProtKB=W5NNU0 W5NNU0 PTHR23349:SF66 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TWIST HOMLOG 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000004448.1|UniProtKB=W5MAA2 W5MAA2 PAFAH1B1 PTHR44129:SF20 WD REPEAT-CONTAINING PROTEIN POP1 LISSENCEPHALY-1 HOMOLOG A-RELATED microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017908.1|UniProtKB=W5NN02 W5NN02 PTHR46481:SF15 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000003505.1|UniProtKB=W5M702 W5M702 PTHR11851:SF229 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585 membrane-enclosed lumen#GO:0031974;peptidase complex#GO:1905368;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;endopeptidase complex#GO:1905369;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000004453.1|UniProtKB=W5MAB3 W5MAB3 PTHR43625:SF4 AFLATOXIN B1 ALDEHYDE REDUCTASE ALDO-KETO REDUCTASE FAMILY 7 MEMBER A2 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000009440.1|UniProtKB=W5MT20 W5MT20 PTHR11564:SF40 SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54 GTPase activity#GO:0003924;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;hydrolase activity#GO:0016787;RNA binding#GO:0003723;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;signal sequence receptor activity#GO:0005048 protein targeting#GO:0006605;localization within membrane#GO:0051668;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;transport#GO:0006810;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;intracellular protein transport#GO:0006886;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047 ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016965.1|UniProtKB=W5NK12 W5NK12 PTHR12894:SF30 CNH DOMAIN CONTAINING TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1 ISOFORM X1 establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;transport#GO:0006810;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;vesicle fusion#GO:0006906;membrane organization#GO:0061024;cellular component organization#GO:0016043;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987 organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 LEPOC|Ensembl=ENSLOCG00000008678.1|UniProtKB=W5MQ94 W5MQ94 PTHR42753:SF10 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER PROLINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006303.1|UniProtKB=W5MGV9 W5MGV9 PTHR18884:SF67 SEPTIN SEPTIN-2 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;cell division#GO:0051301;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;cilium organization#GO:0044782;cytokinesis#GO:0000910;organelle assembly#GO:0070925 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cell cortex#GO:0005938;cell periphery#GO:0071944 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 LEPOC|Ensembl=ENSLOCG00000003752.1|UniProtKB=W5M7W0 W5M7W0 PTHR23414:SF3 ADRENOMEDULLIN, ADM PRO-ADRENOMEDULLIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;renal system process#GO:0003014;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of system process#GO:0044057;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;system process#GO:0003008;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of heart contraction#GO:0008016;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;cell communication#GO:0007154;regulation of biological quality#GO:0065008 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000001147.1|UniProtKB=W5LYT4 W5LYT4 PTHR34488:SF1 SI:CH211-245H14.1-RELATED SI:CH211-245H14.1-RELATED LEPOC|Ensembl=ENSLOCG00000000827.1|UniProtKB=W5LXR3 W5LXR3 PTHR12002:SF184 CLAUDIN CLAUDIN cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;cell junction organization#GO:0034330 tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000000790.1|UniProtKB=W5LXN0 W5LXN0 PTHR46806:SF4 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN NEUROPILIN-1 transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023 axon guidance#GO:0007411;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell projection organization#GO:0031344;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;regulation of response to stimulus#GO:0048583;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of filopodium assembly#GO:0051489;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;mesenchyme development#GO:0060485;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cell communication#GO:0010646;stem cell development#GO:0048864;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell projection organization#GO:0031346;anatomical structure development#GO:0048856;neuron projection development#GO:0031175;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neural crest cell migration#GO:0001755;vasculogenesis#GO:0001570;positive regulation of cellular component biogenesis#GO:0044089;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;vascular endothelial growth factor receptor signaling pathway#GO:0048010;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;angiogenesis#GO:0001525;axonogenesis#GO:0007409;neuron development#GO:0048666;stem cell differentiation#GO:0048863;axon development#GO:0061564;response to wounding#GO:0009611;tissue development#GO:0009888;neural crest cell development#GO:0014032;cell migration#GO:0016477;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;tube development#GO:0035295;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;cellular developmental process#GO:0048869;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;cell communication#GO:0007154;regulation of cell motility#GO:2000145;enzyme-linked receptor protein signaling pathway#GO:0007167;system development#GO:0048731;regulation of cell projection assembly#GO:0060491;response to stress#GO:0006950;neural crest cell differentiation#GO:0014033;mesenchymal cell differentiation#GO:0048762;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;animal organ development#GO:0048513;cell projection morphogenesis#GO:0048858;positive regulation of cell motility#GO:2000147;blood vessel morphogenesis#GO:0048514;cellular component organization#GO:0016043;circulatory system development#GO:0072359;cell projection organization#GO:0030030;cell differentiation#GO:0030154;signaling#GO:0023052;sprouting angiogenesis#GO:0002040;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130 anchoring junction#GO:0070161;cell junction#GO:0030054;axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 Axon guidance mediated by semaphorins#P00007>Neuropilin 1#P00338 LEPOC|Ensembl=ENSLOCG00000008014.1|UniProtKB=W5MMX9 W5MMX9 PTHR13621:SF2 PROLINE-RICH PROTEIN PRCC PROLINE-RICH PROTEIN PRCC intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017985.1|UniProtKB=W5NN77 W5NN77 PTHR10502:SF210 ANNEXIN PRION PROTEIN 1 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phospholipid binding#GO:0005543;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;nucleus#GO:0005634;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000011553.1|UniProtKB=W5N0P2 W5N0P2 PTHR24103:SF590 E3 UBIQUITIN-PROTEIN LIGASE TRIM BUTYROPHILIN SUBFAMILY 3 MEMBER A1-LIKE catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000000379.1|UniProtKB=W5LWA5 W5LWA5 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune response#GO:0006955;adaptive immune response#GO:0002250;response to stimulus#GO:0050896 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016290.1|UniProtKB=W5NHK3 W5NHK3 PTHR11339:SF225 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED OTOGELIN-LIKE PROTEIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000005791.1|UniProtKB=W5MF36 W5MF36 PTHR31838:SF1 CENTROSOMAL PROTEIN OF 55 KDA CENTROSOMAL PROTEIN OF 55 KDA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 membrane organization#GO:0061024;cellular process#GO:0009987;establishment of protein localization#GO:0045184;mitotic cell cycle process#GO:1903047;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cell division#GO:0051301;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic cytokinetic process#GO:1902410;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinetic process#GO:0032506;cytokinesis#GO:0000910 cellular anatomical structure#GO:0110165;midbody#GO:0030496 LEPOC|Ensembl=ENSLOCG00000015155.1|UniProtKB=W5NDE1 W5NDE1 PTHR19818:SF25 ZINC FINGER PROTEIN ZIC AND GLI ZIC FAMILY MEMBER 3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000018099.1|UniProtKB=W5NNJ1 W5NNJ1 PTHR24226:SF3 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 G PROTEIN-COUPLED RECEPTOR 146 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001754.1|UniProtKB=W5M0X0 W5M0X0 PTHR12353:SF4 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 3 modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051 cell junction#GO:0030054;postsynaptic specialization#GO:0099572;organelle#GO:0043226;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007665.1|UniProtKB=W5MLP9 W5MLP9 PTHR11347:SF91 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE 4D catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 hydrolase#PC00121;phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000003374.1|UniProtKB=W5M6I9 W5M6I9 PTHR45685:SF1 HELICASE SRCAP-RELATED CHROMATIN REMODELING PROTEIN DOMINO binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;histone binding#GO:0042393;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Swr1 complex#GO:0000812;ATPase complex#GO:1904949;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000008591.1|UniProtKB=W5MPY9 W5MPY9 PTHR45656:SF8 PROTEIN CBR-CLEC-78 SEIZURE 6-LIKE PROTEIN synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;cell junction organization#GO:0034330;central nervous system development#GO:0007417;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;nervous system development#GO:0007399;head development#GO:0060322;multicellular organismal process#GO:0032501;brain development#GO:0007420;developmental maturation#GO:0021700 intracellular organelle#GO:0043229;postsynaptic membrane#GO:0045211;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell body#GO:0044297;postsynapse#GO:0098794;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic membrane#GO:0097060;endoplasmic reticulum#GO:0005783;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;endomembrane system#GO:0012505;plasma membrane region#GO:0098590 LEPOC|Ensembl=ENSLOCG00000011696.1|UniProtKB=W5N162 W5N162 PTHR14256:SF4 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE SUBUNIT FA4 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;transporter complex#GO:1990351 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009635.1|UniProtKB=W5MTS6 W5MTS6 PTHR21686:SF12 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000012487.1|UniProtKB=W5N409 W5N409 PTHR11889:SF85 HEDGEHOG SONIC HEDGEHOG PROTEIN-RELATED ion binding#GO:0043167;small molecule binding#GO:0036094;signaling receptor binding#GO:0005102;binding#GO:0005488;calcium ion binding#GO:0005509;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169 biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;cell fate specification#GO:0001708;cell surface receptor signaling pathway#GO:0007166;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;cell fate commitment#GO:0045165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Hedgehog signaling pathway#P00025>Hedgehog#P00688 LEPOC|Ensembl=ENSLOCG00000003555.1|UniProtKB=W5M749 W5M749 PTHR23136:SF8 TAX1-BINDING PROTEIN 3-RELATED ALPHA-N-ACETYLNEURAMINYL-2,3-BETA-GALACTOSYL-1,3-N-ACETYLGALACTOSAMINIDE6-ALPHA-SIALYLTRANSFERASE LEPOC|Ensembl=ENSLOCG00000016169.1|UniProtKB=W5NH14 W5NH14 PTHR10656:SF35 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;regulation of DNA metabolic process#GO:0051052;regulation of double-strand break repair via homologous recombination#GO:0010569;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;negative regulation of double-strand break repair via homologous recombination#GO:2000042;positive regulation of response to external stimulus#GO:0032103;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of multicellular organismal process#GO:0051239;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;positive regulation of cytokine production#GO:0001819;regulation of response to biotic stimulus#GO:0002831;regulation of response to stress#GO:0080134;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;activation of innate immune response#GO:0002218;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of innate immune response#GO:0045089;cellular response to nitrogen compound#GO:1901699;negative regulation of DNA metabolic process#GO:0051053;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;response to stimulus#GO:0050896;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of double-strand break repair#GO:2000779;negative regulation of DNA recombination#GO:0045910;positive regulation of type I interferon production#GO:0032481;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of cellular process#GO:0048523;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;DNA damage response#GO:0006974;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of response to biotic stimulus#GO:0002833;regulation of primary metabolic process#GO:0080090;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 nucleotidyltransferase#PC00174;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000000532.1|UniProtKB=W5LWT1 W5LWT1 PTHR46890:SF1 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED SECRETED RXLR EFFECTOR PROTEIN 78-LIKE viral or transposable element protein#PC00237;reverse transcriptase#PC00200 LEPOC|Ensembl=ENSLOCG00000017245.1|UniProtKB=W5NL21 W5NL21 PTHR31075:SF2 CENTROSOMAL PROTEIN OF 85 KDA CENTROSOMAL PROTEIN OF 85 KDA-LIKE membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000004094.1|UniProtKB=W5M932 W5M932 PTHR43270:SF1 BETA-ALA-HIS DIPEPTIDASE BETA-ALA-HIS DIPEPTIDASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000005190.1|UniProtKB=W5MD08 W5MD08 PTHR45814:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1B N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;histone H3K4 methyltransferase activity#GO:0042800;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000004726.1|UniProtKB=W5MBA7 W5MBA7 PTHR14732:SF0 RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA transcription#GO:0009301;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000007684.1|UniProtKB=W5MLS2 W5MLS2 PTHR13906:SF14 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 5 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphatidylcholine biosynthetic process#GO:0006656;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;lipid modification#GO:0030258 membrane#GO:0016020;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000000975.1|UniProtKB=W5LY89 W5LY89 PTHR47228:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 16 SPERMATOGENESIS-ASSOCIATED PROTEIN 16 multicellular organismal reproductive process#GO:0048609;developmental process#GO:0032502;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000008735.1|UniProtKB=W5MQH3 W5MQH3 PTHR11660:SF47 SOLUTE CARRIER FAMILY 40 MEMBER FERROPORTIN transition metal ion transmembrane transporter activity#GO:0046915;binding#GO:0005488;iron ion transmembrane transporter activity#GO:0005381;monoatomic cation transmembrane transporter activity#GO:0008324;hormone binding#GO:0042562;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;peptide hormone binding#GO:0017046;metal ion transmembrane transporter activity#GO:0046873 transition metal ion transport#GO:0000041;transport#GO:0006810;iron ion transmembrane transport#GO:0034755;iron ion transport#GO:0006826;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014396.1|UniProtKB=W5NAR9 W5NAR9 PTHR10878:SF8 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-2 frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Wnt signaling pathway#P00057>Dishevelled#P01447;Alzheimer disease-presenilin pathway#P00004>Dsh#P00132 LEPOC|Ensembl=ENSLOCG00000010346.1|UniProtKB=W5MWB9 W5MWB9 PTHR15375:SF22 ACTIVATOR OF S-PHASE KINASE-RELATED PROTEIN DBF4 HOMOLOG A kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;positive regulation of DNA metabolic process#GO:0051054;regulation of cell cycle phase transition#GO:1901987;regulation of DNA metabolic process#GO:0051052;regulation of DNA-templated DNA replication#GO:0090329;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of DNA replication#GO:0006275;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of DNA replication#GO:0045740;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 kinase activator#PC00138;kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000014282.1|UniProtKB=W5NAC6 W5NAC6 PTHR13318:SF186 PARTNER OF PAIRED, ISOFORM B-RELATED DISTAL MEMBRANE-ARM ASSEMBLY COMPLEX PROTEIN 2 NADH dehydrogenase complex assembly#GO:0010257;ubiquitin-dependent protein catabolic process#GO:0006511;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;protein-containing complex assembly#GO:0065003;modification-dependent protein catabolic process#GO:0019941;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461 LEPOC|Ensembl=ENSLOCG00000005173.1|UniProtKB=W5MCX1 W5MCX1 PTHR14572:SF0 PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR LEPOC|Ensembl=ENSLOCG00000018114.1|UniProtKB=W5NNK6 W5NNK6 PTHR11818:SF107 BETA/GAMMA CRYSTALLIN CRYGMX PROTEIN structural molecule activity#GO:0005198 sensory system development#GO:0048880;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;system process#GO:0003008;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;sensory perception#GO:0007600;nervous system process#GO:0050877;anatomical structure development#GO:0048856;system development#GO:0048731;eye development#GO:0001654 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008731.1|UniProtKB=W5MQI1 W5MQI1 PTHR16311:SF3 THROMBOSPONDIN TYPE I DOMAIN-CONTAINING 1 THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000015752.1|UniProtKB=W5NFI5 W5NFI5 PTHR15989:SF5 VEZATIN VEZATIN cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000011578.1|UniProtKB=W5N0S7 W5N0S7 PTHR14493:SF36 UNKEMPT FAMILY MEMBER RING FINGER PROTEIN UNKEMPT HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000013230.1|UniProtKB=W5N6P4 W5N6P4 PTHR11827:SF93 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 1 symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;solute:sodium symporter activity#GO:0015370;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000000118.1|UniProtKB=W5LVH5 W5LVH5 PTHR26451:SF52 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 12D2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006594.1|UniProtKB=W5MHV6 W5MHV6 PTHR28574:SF1 RIKEN CDNA 6820408C15 RIKEN CDNA 6820408C15 GENE LEPOC|Ensembl=ENSLOCG00000017176.1|UniProtKB=W5NKS0 W5NKS0 PTHR11003:SF104 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 16 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000013417.1|UniProtKB=W5N7D5 W5N7D5 PTHR22812:SF159 CHROMOBOX PROTEIN CHROMOBOX 1 binding#GO:0005488;chromatin binding#GO:0003682 regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687 LEPOC|Ensembl=ENSLOCG00000003876.1|UniProtKB=W5M8B0 W5M8B0 PTHR14015:SF1 OPIOID GROWTH FACTOR RECEPTOR OGFR ZETA-TYPE OPIOID RECEPTOR OPIOID GROWTH FACTOR RECEPTOR transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000007518.1|UniProtKB=W5ML72 W5ML72 PTHR14095:SF3 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT ALPHA phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 anterior/posterior pattern specification#GO:0009952;regulation of cell migration#GO:0030334;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of canonical Wnt signaling pathway#GO:0060828;epithelium development#GO:0060429;regionalization#GO:0003002;multicellular organismal process#GO:0032501;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;embryo development#GO:0009790;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;regulation of signaling#GO:0023051;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005087.1|UniProtKB=W5MCM0 W5MCM0 MOCOS PTHR14237:SF96 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MOLYBDENUM COFACTOR SULFURASE sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 LEPOC|Ensembl=ENSLOCG00000000342.1|UniProtKB=W5LW67 W5LW67 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;immune response#GO:0006955;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;immune system process#GO:0002376 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015017.1|UniProtKB=W5NCX7 W5NCX7 PTHR24340:SF32 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000016083.1|UniProtKB=W5NGQ7 W5NGQ7 PTHR15698:SF9 PROTEIN CBG15099 PHYTANOYL-COA HYDROXYLASE-INTERACTING PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000008931.1|UniProtKB=W5MR67 W5MR67 PTHR12262:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;CCR4-NOT complex#GO:0030014;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000015676.1|UniProtKB=W5NF97 W5NF97 PTHR45653:SF3 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 5 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 cell differentiation#GO:0030154;cell migration#GO:0016477;muscle structure development#GO:0061061;cell motility#GO:0048870;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;myoblast fusion#GO:0007520;striated muscle cell differentiation#GO:0051146;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000015613.1|UniProtKB=W5NF13 W5NF13 PTHR22969:SF7 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of signaling#GO:0023056;response to peptide#GO:1901652;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;response to tumor necrosis factor#GO:0034612;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of RNA metabolic process#GO:0051254;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;tumor necrosis factor-mediated signaling pathway#GO:0033209;regulation of RNA metabolic process#GO:0051252;cytokine-mediated signaling pathway#GO:0019221 intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>IKK#P00313;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871;Interleukin signaling pathway#P00036>Ikk#P00968;Toll receptor signaling pathway#P00054>IKKbeta#P01360;B cell activation#P00010>IKK#P00397;T cell activation#P00053>IKK#P01330;PDGF signaling pathway#P00047>Ikk#P01146 LEPOC|Ensembl=ENSLOCG00000006001.1|UniProtKB=W5MFU4 W5MFU4 PTHR46573:SF1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000009826.1|UniProtKB=W5MUF6 W5MUF6 PTHR10131:SF76 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 3 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 signal transduction#GO:0007165;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016582.1|UniProtKB=W5NIM4 W5NIM4 QRSL1 PTHR11895:SF179 TRANSAMIDASE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000007910.1|UniProtKB=W5MMJ9 W5MMJ9 PTHR24089:SF262 SOLUTE CARRIER FAMILY 25 SOLUTE CARRIER FAMILY 25 MEMBER 24 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;establishment of localization#GO:0051234;carbohydrate derivative transport#GO:1901264;transport#GO:0006810;nitrogen compound transport#GO:0071705 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000006307.1|UniProtKB=W5MGW1 W5MGW1 PTHR13388:SF23 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132C membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006317.1|UniProtKB=W5MGY9 W5MGY9 PTHR13008:SF7 MAP-KINASE ACTIVATING DEATH DOMAIN PROTEIN MADD /DENN/AEX-3 C.ELEGANS MAP KINASE-ACTIVATING DEATH DOMAIN PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of apoptotic process#GO:0042981;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Apoptosis signaling pathway#P00006>MADD#P00267 LEPOC|Ensembl=ENSLOCG00000004443.1|UniProtKB=W5MA98 W5MA98 PTHR24388:SF37 ZINC FINGER PROTEIN SNAIL FAMILY TRANSCRIPTIONAL REPRESSOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000003185.1|UniProtKB=W5M5X2 W5M5X2 PTHR43066:SF28 RHOMBOID-RELATED PROTEIN UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 2 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007244.1|UniProtKB=W5MK55 W5MK55 PTHR24369:SF221 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000005653.1|UniProtKB=W5MEL6 W5MEL6 PTHR21381:SF3 ZGC:162297 SGC REGION PROTEIN SGCQ-RELATED LEPOC|Ensembl=ENSLOCG00000016293.1|UniProtKB=W5NHJ8 W5NHJ8 PTHR16255:SF1 REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000012087.1|UniProtKB=W5N2L7 W5N2L7 PTHR10454:SF31 CASPASE CASPASE-7 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of neuron apoptotic process#GO:0043523;biological regulation#GO:0065007;cell death#GO:0008219;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>Caspase 7#P00300;FAS signaling pathway#P00020>Pro-Caspase7#P00605;FAS signaling pathway#P00020>Caspase7#P00595 LEPOC|Ensembl=ENSLOCG00000005199.1|UniProtKB=W5MCZ9 W5MCZ9 PTHR24207:SF0 ZYX102 PROTEIN LIPOMA-PREFERRED PARTNER cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cytoskeleton#GO:0005856;stress fiber#GO:0001725;intracellular organelle#GO:0043229;cell junction#GO:0030054;membraneless organelle#GO:0043228;actin filament bundle#GO:0032432;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055 kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000000475.1|UniProtKB=W5LWL4 W5LWL4 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014685.1|UniProtKB=W5NBR6 W5NBR6 PTHR19282:SF48 TETRASPANIN TETRASPANIN-3 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012564.1|UniProtKB=W5N4A9 W5N4A9 PTHR28602:SF2 ENDOTHELIAL CELL-SPECIFIC CHEMOTAXIS REGULATOR ENDOTHELIAL CELL-SPECIFIC CHEMOTAXIS REGULATOR ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000004791.1|UniProtKB=W5MBI6 W5MBI6 PTHR31638:SF3 DAZ-ASSOCIATED PROTEIN 2 DAZ-ASSOCIATED PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000015390.1|UniProtKB=W5NE79 W5NE79 PTHR21493:SF79 CGI-141-RELATED/LIPASE CONTAINING PROTEIN VESICLE TRANSPORT PROTEIN GOT1B membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013521.1|UniProtKB=W5N7Q9 W5N7Q9 PTHR10519:SF74 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;cellular process#GO:0009987;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 LEPOC|Ensembl=ENSLOCG00000000327.1|UniProtKB=W5LW44 W5LW44 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014271.1|UniProtKB=W5NAA9 W5NAA9 PTHR24100:SF155 BUTYROPHILIN CD276 ANTIGEN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011430.1|UniProtKB=W5N085 W5N085 PTHR23250:SF3 DYSFERLIN-RELATED FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000008837.1|UniProtKB=W5MQU1 W5MQU1 PTHR12489:SF16 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 6 PROTEIN-RELATED cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007391.1|UniProtKB=W5MKQ7 W5MKQ7 PTHR23235:SF26 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP9 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000010679.1|UniProtKB=W5MXG9 W5MXG9 PTHR10281:SF24 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 2 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016896.1|UniProtKB=W5NJS6 W5NJS6 PTHR45632:SF29 LD33804P KELCH-LIKE PROTEIN 31 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein metabolic process#GO:0019538;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;regulation of JNK cascade#GO:0046328;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013352.1|UniProtKB=W5N747 W5N747 PTHR12015:SF198 SMALL INDUCIBLE CYTOKINE A INTERLEUKIN-8 cytokine activity#GO:0005125;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;response to bacterium#GO:0009617;chemotaxis#GO:0006935;inflammatory response#GO:0006954;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell chemotaxis#GO:0060326;immune response#GO:0006955;cell migration#GO:0016477;response to other organism#GO:0051707;leukocyte migration#GO:0050900;cellular response to molecule of bacterial origin#GO:0071219;myeloid leukocyte migration#GO:0097529;response to external stimulus#GO:0009605;defense response#GO:0006952;leukocyte chemotaxis#GO:0030595;response to molecule of bacterial origin#GO:0002237;response to stimulus#GO:0050896;granulocyte chemotaxis#GO:0071621;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular response to lipopolysaccharide#GO:0071222;cellular response to oxygen-containing compound#GO:1901701;defense response to symbiont#GO:0140546;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;neutrophil migration#GO:1990266;granulocyte migration#GO:0097530;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;defense response to other organism#GO:0098542;neutrophil chemotaxis#GO:0030593;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to lipopolysaccharide#GO:0032496 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083 CCKR signaling map#P06959>IL8#G07296;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856;CCKR signaling map#P06959>IL8#G07001;CCKR signaling map#P06959>IL8#P07136;Interleukin signaling pathway#P00036>Interleukin#P00970 LEPOC|Ensembl=ENSLOCG00000000740.1|UniProtKB=W5LXG9 W5LXG9 PTHR10794:SF60 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002167.1|UniProtKB=W5M2D2 W5M2D2 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular process#GO:0009987;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular response to stimulus#GO:0051716;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of immune response#GO:0050776;cell communication#GO:0007154;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000017243.1|UniProtKB=W5NL18 W5NL18 PTHR14233:SF10 DUF914-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F1 LEPOC|Ensembl=ENSLOCG00000001873.1|UniProtKB=W5M1B2 W5M1B2 PTHR13624:SF3 RE42071P TRANSMEMBRANE PROTEIN 161B LEPOC|Ensembl=ENSLOCG00000011787.1|UniProtKB=W5N1I3 W5N1I3 PTHR11249:SF3 GLIAL FACTOR NATURATION FACTOR GLIA MATURATION FACTOR BETA protein-containing complex binding#GO:0044877;binding#GO:0005488 regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of biological process#GO:0048519;negative regulation of cytoskeleton organization#GO:0051494;actin filament-based process#GO:0030029;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000002660.1|UniProtKB=W5M419 W5M419 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015895.1|UniProtKB=W5NG19 W5NG19 PTHR42985:SF2 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324 monocarboxylic acid transport#GO:0015718;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;vitamin transport#GO:0051180;cellular process#GO:0009987;sodium ion transport#GO:0006814;nitrogen compound transport#GO:0071705 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007105.1|UniProtKB=W5MJP3 W5MJP3 PTHR11211:SF17 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000003044.1|UniProtKB=W5M5H3 W5M5H3 PTHR10663:SF124 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 2 cellular component organization#GO:0016043;Golgi to plasma membrane transport#GO:0006893;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;organelle organization#GO:0006996;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosome organization#GO:0007032;vesicle organization#GO:0016050 Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000018186.1|UniProtKB=W5NNS8 W5NNS8 PTHR36542:SF6 GIG2-LIKE PROTEIN DRED-RELATED GIG2-LIKE PROTEIN DREP-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014182.1|UniProtKB=W5NA11 W5NA11 PTHR11984:SF107 CONNEXIN GAP JUNCTION PROTEIN wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 regulation of biological process#GO:0050789;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cell communication#GO:0007154 membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell junction#GO:0030054;anchoring junction#GO:0070161 cell junction protein#PC00070;gap junction#PC00105 LEPOC|Ensembl=ENSLOCG00000013700.1|UniProtKB=W5N8D8 W5N8D8 PTHR23086:SF22 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 BETA kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transferase#PC00220;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000004712.1|UniProtKB=W5MB98 W5MB98 PTHR23030:SF39 PCD6 INTERACTING PROTEIN-RELATED PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;endosomal transport#GO:0016197;cell cycle process#GO:0022402;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;establishment of protein localization to vacuole#GO:0072666;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cytokinesis#GO:0000910;protein transport#GO:0015031;cellular localization#GO:0051641;cytoskeleton-dependent cytokinesis#GO:0061640;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;cell division#GO:0051301;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cell cycle#GO:0007049;protein localization to organelle#GO:0033365;mitotic cytokinesis#GO:0000281;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006182.1|UniProtKB=W5MGG2 W5MGG2 PTHR12606:SF30 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 1 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008387.1|UniProtKB=W5MP78 W5MP78 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006480.1|UniProtKB=W5MHG5 W5MHG5 PTHR12322:SF123 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 2B RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;sex differentiation#GO:0007548;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;reproductive process#GO:0022414 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015631.1|UniProtKB=W5NF36 W5NF36 PTHR14146:SF4 EXOCYST COMPLEX COMPONENT 4 EXOCYST COMPLEX COMPONENT 4 signaling#GO:0023052;export from cell#GO:0140352;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;secretion by cell#GO:0032940;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;synaptic signaling#GO:0099536;exocytosis#GO:0006887;establishment of localization#GO:0051234;transport#GO:0006810 cell cortex#GO:0005938;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;growth cone#GO:0030426;axon#GO:0030424;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;exocyst#GO:0000145;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;cell junction#GO:0030054 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012877.1|UniProtKB=W5N5E3 W5N5E3 PTHR10511:SF2 GRANULOCYTE COLONY-STIMULATING FACTOR GRANULOCYTE COLONY-STIMULATING FACTOR protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 hemopoiesis#GO:0030097;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of myeloid cell differentiation#GO:0045639;regulation of cell development#GO:0060284;cellular developmental process#GO:0048869;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of developmental process#GO:0050793;cellular response to stimulus#GO:0051716;regulation of hemopoiesis#GO:1903706;cell communication#GO:0007154;anatomical structure development#GO:0048856;cytokine-mediated signaling pathway#GO:0019221;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of multicellular organismal process#GO:0051239;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell differentiation#GO:0045597;response to stimulus#GO:0050896;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;signaling#GO:0023052;cell development#GO:0048468;leukocyte differentiation#GO:0002521;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;mononuclear cell differentiation#GO:1903131;response to peptide#GO:1901652;regulation of myeloid cell differentiation#GO:0045637 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016526.1|UniProtKB=W5NIF4 W5NIF4 PTHR11267:SF83 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR T transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 anatomical structure formation involved in morphogenesis#GO:0048646;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;mesoderm development#GO:0007498;animal organ development#GO:0048513;cell fate specification#GO:0001708;anterior/posterior pattern specification#GO:0009952;embryo development#GO:0009790;heart development#GO:0007507;cellular process#GO:0009987;cell fate commitment#GO:0045165;formation of primary germ layer#GO:0001704;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;gastrulation#GO:0007369;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;mesoderm formation#GO:0001707;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;tissue development#GO:0009888;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;tissue morphogenesis#GO:0048729;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;embryo development ending in birth or egg hatching#GO:0009792;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;heart morphogenesis#GO:0003007;mesoderm morphogenesis#GO:0048332 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000015590.1|UniProtKB=W5NEY5 W5NEY5 PTHR12027:SF86 WNT RELATED PROTEIN WNT-2 frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;system development#GO:0048731;cell fate commitment#GO:0045165;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 LEPOC|Ensembl=ENSLOCG00000012906.1|UniProtKB=W5N5I1 W5N5I1 PTHR12550:SF84 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR-RELATED PROTEIN 3 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000003431.1|UniProtKB=W5M6Q4 W5M6Q4 PTHR10654:SF19 CAS SCAFFOLDING PROTEIN CAS SCAFFOLDING PROTEIN FAMILY MEMBER 4 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000014472.1|UniProtKB=W5NB06 W5NB06 PTHR24418:SF263 TYROSINE-PROTEIN KINASE NON-RECEPTOR TYROSINE-PROTEIN KINASE TNK1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000014563.1|UniProtKB=W5NBB6 W5NBB6 PTHR24060:SF24 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 6 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;glutamate receptor signaling pathway#GO:0007215;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044 LEPOC|Ensembl=ENSLOCG00000011999.1|UniProtKB=W5N2A7 W5N2A7 PTHR22870:SF155 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC1-RELATED guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000004609.1|UniProtKB=W5MAW2 W5MAW2 PTHR12015:SF108 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 20 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 LEPOC|Ensembl=ENSLOCG00000004113.1|UniProtKB=W5M958 W5M958 PTHR13180:SF0 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50B transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015814.1|UniProtKB=W5NFR3 W5NFR3 PTHR46513:SF6 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED NIDOGEN-1 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017885.1|UniProtKB=W5NMX9 W5NMX9 PTHR24249:SF417 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 11 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014669.1|UniProtKB=W5NBQ0 W5NBQ0 PTHR12120:SF1 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000017652.1|UniProtKB=W5NM98 W5NM98 PTHR26451:SF876 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000015239.1|UniProtKB=W5NDP3 W5NDP3 PTHR45828:SF33 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SI:DKEY-251I10.2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000001159.1|UniProtKB=W5LYW8 W5LYW8 PTHR16091:SF1 TTC17 PROTEIN TETRATRICOPEPTIDE REPEAT PROTEIN 17 protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;actin filament polymerization#GO:0030041;cell projection organization#GO:0030030;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cilium organization#GO:0044782;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 LEPOC|Ensembl=ENSLOCG00000009710.1|UniProtKB=W5MU07 W5MU07 PTHR16110:SF1 TBC1 DOMAIN FAMILY MEMBER 19 TBC1 DOMAIN FAMILY MEMBER 19 LEPOC|Ensembl=ENSLOCG00000017760.1|UniProtKB=W5NMK5 W5NMK5 PTHR11767:SF43 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 2 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834 inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000002920.1|UniProtKB=W5M4Z9 W5M4Z9 PTHR24278:SF33 COAGULATION FACTOR PROTEIN Z, VITAMIN K-DEPENDENT PLASMA GLYCOPROTEIN A catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000005104.1|UniProtKB=W5MCP8 W5MCP8 PTHR23123:SF10 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 2B histone modifying activity#GO:0140993;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000002775.1|UniProtKB=W5M4G0 W5M4G0 PTHR45744:SF46 TYROSINE AMINOTRANSFERASE TYROSINE AMINOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 transaminase#PC00216 Tyrosine biosynthesis#P02784>Aromatic amino acid aminotransferase#P03213 LEPOC|Ensembl=ENSLOCG00000005704.1|UniProtKB=W5MES5 W5MES5 PTHR23011:SF43 CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 2 ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076 gamete generation#GO:0007276;male gamete generation#GO:0048232;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953 LEPOC|Ensembl=ENSLOCG00000003652.1|UniProtKB=W5M7I1 W5M7I1 PTHR11042:SF72 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018368.1|UniProtKB=W5NPB0 W5NPB0 PTHR26451:SF998 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001382.1|UniProtKB=W5LZK8 W5LZK8 PTHR31051:SF1 PROTEASOME ASSEMBLY CHAPERONE 3 PROTEASOME ASSEMBLY CHAPERONE 3 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000012701.1|UniProtKB=W5N4S0 W5N4S0 PTHR11958:SF109 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 3 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283 L-glutamate import#GO:0051938;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;acidic amino acid transport#GO:0015800;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;establishment of localization#GO:0051234;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 LEPOC|Ensembl=ENSLOCG00000005415.1|UniProtKB=W5MDS4 W5MDS4 PTHR16024:SF7 XK-RELATED PROTEIN XK-RELATED PROTEIN 7 anatomical structure development#GO:0048856;localization#GO:0051179;programmed cell death#GO:0012501;cell death#GO:0008219;organophosphate ester transport#GO:0015748;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;phagocytosis#GO:0006909;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;lipid transport#GO:0006869;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;lipid localization#GO:0010876;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;endocytosis#GO:0006897;membrane invagination#GO:0010324;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;cellular process#GO:0009987;endomembrane system organization#GO:0010256 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000010398.1|UniProtKB=W5MWJ3 W5MWJ3 PTHR10962:SF4 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2B binding#GO:0005488;peptide binding#GO:0042277 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000005016.1|UniProtKB=W5MCD2 W5MCD2 PTHR11818:SF50 BETA/GAMMA CRYSTALLIN BETA_GAMMA CRYSTALLIN DOMAIN-CONTAINING PROTEIN 2 structural molecule activity#GO:0005198 sensory organ development#GO:0007423;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system process#GO:0003008;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;nervous system process#GO:0050877;sensory perception#GO:0007600;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;sensory perception of light stimulus#GO:0050953;visual perception#GO:0007601;visual system development#GO:0150063 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000016935.1|UniProtKB=W5NJX5 W5NJX5 PTHR10367:SF17 MRNA-CAPPING ENZYME MRNA-CAPPING ENZYME catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 mRNA capping factor#PC00145;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000014155.1|UniProtKB=W5N9X7 W5N9X7 PTHR11552:SF231 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE CHOLINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012937.1|UniProtKB=W5N5M4 W5N5M4 PTHR13420:SF7 UPF0235 PROTEIN C15ORF40 UPF0235 PROTEIN C15ORF40 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014185.1|UniProtKB=W5NA12 W5NA12 PTHR46680:SF6 NF-KAPPA-B INHIBITOR ALPHA NFKB INHIBITOR BETA protein sequestering activity#GO:0140311;binding#GO:0005488;transcription factor binding#GO:0008134;molecular sequestering activity#GO:0140313;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515 regulation of cellular process#GO:0050794;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000009122.1|UniProtKB=W5MRX1 W5MRX1 PTHR22836:SF0 WD40 REPEAT PROTEIN PRE-MRNA 3' END PROCESSING PROTEIN WDR33 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000009681.1|UniProtKB=W5MTX4 W5MTX4 PTHR24012:SF409 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1 binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608 organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000814.1|UniProtKB=W5LXP6 W5LXP6 PTHR23351:SF23 FOS TRANSCRIPTION FACTOR-RELATED CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#G06902;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#G06689;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#P06821 LEPOC|Ensembl=ENSLOCG00000000687.1|UniProtKB=W5LXA5 W5LXA5 PTHR24353:SF118 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE PROTEIN KINASE CGMP-DEPENDENT 3 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014405.1|UniProtKB=W5NAS4 W5NAS4 PTHR45911:SF2 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of neurotransmitter secretion#GO:0046928;regulation of trans-synaptic signaling#GO:0099177;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;regulation of secretion#GO:0051046;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of secretion by cell#GO:1903530 cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;presynapse#GO:0098793;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000011567.1|UniProtKB=W5N0Q0 W5N0Q0 PTHR10513:SF19 DEOXYNUCLEOSIDE KINASE DEOXYCYTIDINE KINASE transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;deoxynucleoside kinase activity#GO:0019136;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010035.1|UniProtKB=W5MV75 W5MV75 PTHR11773:SF1 GLYCINE DEHYDROGENASE, DECARBOXYLATING GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012155.1|UniProtKB=W5N2T6 W5N2T6 PTHR15304:SF1 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of MAPK cascade#GO:0043408;negative regulation of RNA metabolic process#GO:0051253;regulation of response to stimulus#GO:0048583;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of JNK cascade#GO:0046328;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012821.1|UniProtKB=W5N567 W5N567 PTHR24027:SF106 CADHERIN-23 CADHERIN-18 protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;cell motility#GO:0048870;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component biogenesis#GO:0044085;cell migration#GO:0016477;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000018260.1|UniProtKB=W5NP02 W5NP02 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008360.1|UniProtKB=W5MP46 W5MP46 PTHR23412:SF18 STEREOCILIN RELATED OTOANCORIN cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000010937.1|UniProtKB=W5MYG0 W5MYG0 PTHR10010:SF21 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2A metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;phosphate transmembrane transporter activity#GO:0005315 phosphate ion transport#GO:0006817;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;localization#GO:0051179;chemical homeostasis#GO:0048878;transport#GO:0006810;inorganic ion homeostasis#GO:0098771 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell periphery#GO:0071944;brush border#GO:0005903;apical plasma membrane#GO:0016324;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;apical part of cell#GO:0045177 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000015830.1|UniProtKB=W5NFS8 W5NFS8 PTHR16024:SF9 XK-RELATED PROTEIN XK-RELATED PROTEIN 6 organophosphate ester transport#GO:0015748;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;programmed cell death#GO:0012501;cell death#GO:0008219;localization#GO:0051179;anatomical structure development#GO:0048856;lipid transport#GO:0006869;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;phagocytosis#GO:0006909;developmental process#GO:0032502;transport#GO:0006810;endocytosis#GO:0006897;cellular component organization#GO:0016043;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;endomembrane system organization#GO:0010256;cellular process#GO:0009987;apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;membrane invagination#GO:0010324 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000003021.1|UniProtKB=W5M5A0 W5M5A0 PTHR20982:SF14 RIBOSOME RECYCLING FACTOR RIBOSOME-RECYCLING FACTOR, MITOCHONDRIAL ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 protein-containing complex disassembly#GO:0032984;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mitochondrial gene expression#GO:0140053;organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;translation#GO:0006412;translational termination#GO:0006415;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 translation release factor#PC00225 LEPOC|Ensembl=ENSLOCG00000008727.1|UniProtKB=W5MQG3 W5MQG3 PTHR23092:SF24 POLY(A) RNA POLYMERASE TERMINAL NUCLEOTIDYLTRANSFERASE 4A transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;modification-dependent macromolecule catabolic process#GO:0043632;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000009599.1|UniProtKB=W5MTL7 W5MTL7 PTHR12925:SF2 HIKESHI FAMILY MEMBER PROTEIN HIKESHI binding#GO:0005488;molecular carrier activity#GO:0140104;protein-folding chaperone binding#GO:0051087;heat shock protein binding#GO:0031072;nucleocytoplasmic carrier activity#GO:0140142;protein binding#GO:0005515;Hsp70 protein binding#GO:0030544 establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001775.1|UniProtKB=W5M0Z4 W5M0Z4 PTHR10071:SF23 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016056.1|UniProtKB=W5NGM2 W5NGM2 PTHR12965:SF0 VACUOLAR PROTEIN SORTING 54 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018076.1|UniProtKB=W5NNG8 W5NNG8 PTHR11505:SF205 L1 TRANSPOSABLE ELEMENT-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000007394.1|UniProtKB=W5MKR9 W5MKR9 PTHR15911:SF6 WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;RNA polymerase binding#GO:0070063;chromatin binding#GO:0003682;enzyme binding#GO:0019899 regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of metabolic process#GO:0019222;positive regulation of TORC1 signaling#GO:1904263;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007614.1|UniProtKB=W5MLH7 W5MLH7 PTHR12458:SF11 ORF PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 20 developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule bundle formation#GO:0001578;spermatid development#GO:0007286;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;male gamete generation#GO:0048232;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;cilium assembly#GO:0060271;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;sperm motility#GO:0097722;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;multicellular organism development#GO:0007275;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;microtubule-based process#GO:0007017 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;sperm flagellum#GO:0036126;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 LEPOC|Ensembl=ENSLOCG00000001870.1|UniProtKB=W5M1D3 W5M1D3 PTHR11409:SF52 ADENOSINE DEAMINASE ADENOSINE DEAMINASE catalytic activity#GO:0003824;adenosine deaminase activity#GO:0004000;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 nucleobase metabolic process#GO:0009112;small molecule biosynthetic process#GO:0044283;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;cell activation#GO:0001775;purine nucleoside metabolic process#GO:0042278;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;leukocyte activation#GO:0045321;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;lymphocyte activation#GO:0046649;cellular process#GO:0009987;adenosine metabolic process#GO:0046085;nucleoside catabolic process#GO:0009164;purine-containing compound biosynthetic process#GO:0072522;immune system process#GO:0002376;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;T cell activation#GO:0042110;nucleobase-containing small molecule catabolic process#GO:0034656;purine-containing compound metabolic process#GO:0072521 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 deaminase#PC00088 LEPOC|Ensembl=ENSLOCG00000005108.1|UniProtKB=W5MCP7 W5MCP7 PTHR47979:SF150 DRAB11-RELATED RAB2A, MEMBER RAS ONCOGENE FAMILY ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 small GTPase#PC00208;G-protein#PC00020 PDGF signaling pathway#P00047>Ras#P01154 LEPOC|Ensembl=ENSLOCG00000008963.1|UniProtKB=W5MRB5 W5MRB5 PTHR12546:SF36 FER-1-LIKE FER-1-LIKE PROTEIN 4 cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000000010.1|UniProtKB=W5LV54 W5LV54 PTHR46066:SF2 CHITINASE DOMAIN-CONTAINING PROTEIN 1 FAMILY MEMBER CHITINASE DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;oligosaccharide binding#GO:0070492;carbohydrate binding#GO:0030246 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000002891.1|UniProtKB=W5M4U3 W5M4U3 PTHR21345:SF5 SPIRE PROTEIN SPIRE HOMOLOG 2 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;meiotic cell cycle#GO:0051321;membrane invagination#GO:0010324;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;gamete generation#GO:0007276;establishment of organelle localization#GO:0051656;cytokinesis#GO:0000910;nuclear division#GO:0000280;cytokinetic process#GO:0032506;cytoskeleton-dependent cytokinesis#GO:0061640;spindle localization#GO:0051653;cellular localization#GO:0051641;establishment of spindle localization#GO:0051293;membrane organization#GO:0061024;intracellular transport#GO:0046907;transport#GO:0006810;meiotic nuclear division#GO:0140013;establishment of localization#GO:0051234;actin filament organization#GO:0007015;cell cycle#GO:0007049;cell division#GO:0051301;actin cytoskeleton organization#GO:0030036;reproductive process#GO:0022414;organelle localization#GO:0051640;sexual reproduction#GO:0019953;actin filament-based process#GO:0030029;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;supramolecular fiber organization#GO:0097435;multicellular organismal reproductive process#GO:0048609 organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;cell cortex#GO:0005938;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000017294.1|UniProtKB=W5NL90 W5NL90 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED SI:DKEYP-69E1.8 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000011238.1|UniProtKB=W5MZJ9 W5MZJ9 PTHR11035:SF16 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 4 catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 dehydratase#PC00091 LEPOC|Ensembl=ENSLOCG00000014222.1|UniProtKB=W5NA56 W5NA56 PTHR45797:SF1 RAD54-LIKE HELICASE ARIP4 catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;transcription regulator activity#GO:0140110;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transcription coregulator activity#GO:0003712 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006381.1|UniProtKB=W5MH45 W5MH45 PTHR42757:SF44 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 141 heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010806.1|UniProtKB=W5MXY4 W5MXY4 PTHR45617:SF186 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012978.1|UniProtKB=W5N5S2 W5N5S2 PTHR14453:SF107 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE transferase activity#GO:0016740;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;glycosyltransferase activity#GO:0016757;transcription regulator activity#GO:0140110;pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950 regulation of biological process#GO:0050789;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biological process#GO:0048519;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of gene expression#GO:0010629;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000006312.1|UniProtKB=W5MGV8 W5MGV8 PTHR31655:SF3 PROTEIN FAM78A PROTEIN FAM78A LEPOC|Ensembl=ENSLOCG00000017887.1|UniProtKB=W5NMY1 W5NMY1 PTHR24249:SF415 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014425.1|UniProtKB=W5NAU5 W5NAU5 PTHR12307:SF40 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3F protein phosphatase binding#GO:0019903;carbohydrate binding#GO:0030246;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of polysaccharide metabolic process#GO:0032881;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000017957.1|UniProtKB=W5NN51 W5NN51 PTHR11829:SF209 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN B1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000009106.1|UniProtKB=W5MRU3 W5MRU3 PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 LEPOC|Ensembl=ENSLOCG00000013999.1|UniProtKB=W5N9E7 W5N9E7 PTHR11644:SF26 CYTIDINE DEAMINASE ZGC:103586 ISOFORM X1 deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 nucleoside catabolic process#GO:0009164;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 deaminase#PC00088 LEPOC|Ensembl=ENSLOCG00000003028.1|UniProtKB=W5M5A9 W5M5A9 PTHR45767:SF5 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O6 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000013405.1|UniProtKB=W5N7B8 W5N7B8 PTHR12309:SF5 SEC61 GAMMA SUBUNIT PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization to endoplasmic reticulum#GO:0072599;localization within membrane#GO:0051668;protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;rough endoplasmic reticulum#GO:0005791;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000004578.1|UniProtKB=W5MAS4 W5MAS4 PTHR45636:SF48 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-6 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 sensory organ development#GO:0007423;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelium development#GO:0060429;brain development#GO:0007420;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;camera-type eye development#GO:0043010;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;pancreas development#GO:0031016;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;visual system development#GO:0150063;multicellular organism development#GO:0007275;animal organ development#GO:0048513;sensory system development#GO:0048880;cellular process#GO:0009987;head development#GO:0060322;retina development in camera-type eye#GO:0060041;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;eye development#GO:0001654;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;forebrain development#GO:0030900 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000007508.1|UniProtKB=W5ML53 W5ML53 PTHR15536:SF1 TACHYKININ-3 TACHYKININ-3 multicellular organismal process#GO:0032501;blood circulation#GO:0008015;positive regulation of blood pressure#GO:0045777;biological regulation#GO:0065007;regulation of blood pressure#GO:0008217;regulation of biological quality#GO:0065008;system process#GO:0003008;circulatory system process#GO:0003013 LEPOC|Ensembl=ENSLOCG00000010003.1|UniProtKB=W5MV20 W5MV20 PTHR15040:SF3 DERMATOPONTIN-RELATED SI:DKEY-14D8.6-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000014632.1|UniProtKB=W5NBK6 W5NBK6 PTHR11835:SF60 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;alcohol metabolic process#GO:0006066;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000009087.1|UniProtKB=W5MRS6 W5MRS6 PTHR12761:SF1 HERMANSKY-PUDLAK SYNDROME PROTEIN 1 BLOC-3 COMPLEX MEMBER HPS1 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;organelle assembly#GO:0070925;melanosome organization#GO:0032438;pigmentation#GO:0043473;cellular component assembly#GO:0022607;cellular pigmentation#GO:0033059;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000006994.1|UniProtKB=W5MJC0 W5MJC0 PTHR11827:SF46 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 4 solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000006048.1|UniProtKB=W5MFZ3 W5MFZ3 PTHR22168:SF7 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000010802.1|UniProtKB=W5MXY5 W5MXY5 PTHR12680:SF8 PUTATIVE HOMEODOMAIN TRANSCRIPTION FACTOR PHTF PROTEIN PHTF1 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000018044.1|UniProtKB=W5NND6 W5NND6 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007229.1|UniProtKB=W5MK41 W5MK41 PTHR11353:SF24 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT GAMMA cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein folding chaperone complex#GO:0101031;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;chaperonin-containing T-complex#GO:0005832;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000000628.1|UniProtKB=W5LX70 W5LX70 PTHR19971:SF24 SIGNAL-REGULATORY PROTEIN BETA IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001501.1|UniProtKB=W5M005 W5M005 PTHR21349:SF0 50S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;mitochondrial translation#GO:0032543;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 Methylcitrate cycle#P02754>Aconitase#P03028 LEPOC|Ensembl=ENSLOCG00000009305.1|UniProtKB=W5MSJ5 W5MSJ5 PTHR48493:SF1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000012593.1|UniProtKB=W5N4E4 W5N4E4 PTHR24169:SF9 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of transcription by RNA polymerase II#GO:0045944;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;response to cytokine#GO:0034097;positive regulation of macromolecule metabolic process#GO:0010604;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;non-canonical NF-kappaB signal transduction#GO:0038061;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to peptide#GO:1901652;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of gene expression#GO:0010468;innate immune response#GO:0045087;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;response to other organism#GO:0051707;canonical NF-kappaB signal transduction#GO:0007249;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;response to external biotic stimulus#GO:0043207;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;Rel homology transcription factor#PC00252;DNA-binding transcription factor#PC00218 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Apoptosis signaling pathway#P00006>NFkappaB#P00297;B cell activation#P00010>NFkappaB#P00370;Toll receptor signaling pathway#P00054>NFkappaB#P01354;T cell activation#P00053>NFkappaB#P01298 LEPOC|Ensembl=ENSLOCG00000016343.1|UniProtKB=W5NHR7 W5NHR7 PTHR24329:SF359 HOMEOBOX PROTEIN ARISTALESS ALX HOMEOBOX PROTEIN 1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;embryo development ending in birth or egg hatching#GO:0009792;embryonic organ development#GO:0048568;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;generation of neurons#GO:0048699;chordate embryonic development#GO:0043009;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;skeletal system development#GO:0001501;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;embryo development#GO:0009790;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000017859.1|UniProtKB=W5NMV3 W5NMV3 PTHR36542:SF6 GIG2-LIKE PROTEIN DRED-RELATED GIG2-LIKE PROTEIN DREP-RELATED cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000016011.1|UniProtKB=W5NGG4 W5NGG4 PTHR12092:SF1 PLECKSTRIN PLECKSTRIN cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000016564.1|UniProtKB=W5NIK0 W5NIK0 PTHR24006:SF953 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBL CARBOXYL-TERMINAL HYDROLASE 18 ISOFORM X1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008743.1|UniProtKB=W5MQI3 W5MQI3 PTHR11890:SF50 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-18 RECEPTOR 1 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005703.1|UniProtKB=W5MES4 W5MES4 PTHR23349:SF10 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 9 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000002235.1|UniProtKB=W5M2K0 W5M2K0 PTHR10133:SF65 DNA POLYMERASE I DNA POLYMERASE NU transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303 DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000015397.1|UniProtKB=W5NE91 W5NE91 PTHR10603:SF4 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN FRAGILE X MESSENGER RIBONUCLEOPROTEIN 1 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;RNA localization#GO:0006403;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;establishment of RNA localization#GO:0051236;modulation of chemical synaptic transmission#GO:0050804;regulation of developmental process#GO:0050793;mRNA transport#GO:0051028;regulation of cell communication#GO:0010646;positive regulation of neurogenesis#GO:0050769;regulation of neurogenesis#GO:0050767;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;nucleic acid transport#GO:0050657;positive regulation of translation#GO:0045727;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;regulation of translation#GO:0006417;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of neuronal synaptic plasticity#GO:0048168;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of synaptic plasticity#GO:0048167;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;transport#GO:0006810;positive regulation of nervous system development#GO:0051962;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule metabolic process#GO:0010604;regulation of trans-synaptic signaling#GO:0099177;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;animal organ development#GO:0048513;positive regulation of cell differentiation#GO:0045597 nucleus#GO:0005634;neuron projection#GO:0043005;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000002368.1|UniProtKB=W5M326 W5M326 PTHR13257:SF0 NUCLEOPORIN NUP84-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP88 macromolecule biosynthetic process#GO:0009059;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;biosynthetic process#GO:0009058;transport#GO:0006810;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;RNA export from nucleus#GO:0006405;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;organelle localization#GO:0051640;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;protein export from nucleus#GO:0006611;gene expression#GO:0010467;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;ribosomal large subunit export from nucleus#GO:0000055;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;ribosome biogenesis#GO:0042254;protein import into nucleus#GO:0006606;protein transport#GO:0015031;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641 organelle envelope#GO:0031967;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016745.1|UniProtKB=W5NJ85 W5NJ85 PTHR24024:SF43 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A HBL4 PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187 regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;positive regulation of cellular component organization#GO:0051130;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;activation of immune response#GO:0002253;positive regulation of transport#GO:0051050;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;defense response to other organism#GO:0098542;humoral immune response#GO:0006959;immune effector process#GO:0002252;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;regulation of immune response#GO:0050776;positive regulation of cellular process#GO:0048522;complement activation#GO:0006956;immune response#GO:0006955;positive regulation of endocytosis#GO:0045807;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211;surfactant#PC00212 LEPOC|Ensembl=ENSLOCG00000001160.1|UniProtKB=W5LYX3 W5LYX3 PTHR45828:SF44 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000003981.1|UniProtKB=W5M8P3 W5M8P3 PTHR13593:SF32 FAMILY NOT NAMED PI-PLC X DOMAIN-CONTAINING PROTEIN 2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 LEPOC|Ensembl=ENSLOCG00000004441.1|UniProtKB=W5MAA9 W5MAA9 PTHR11269:SF9 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription factor binding#GO:0008134 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;rhythmic process#GO:0048511;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;circadian rhythm#GO:0007623;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;photoperiodism#GO:0009648;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of circadian rhythm#GO:0042752;response to radiation#GO:0009314;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 transcription cofactor#PC00217 Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>per#G01499;Circadian clock system#P00015>Per#P00504 LEPOC|Ensembl=ENSLOCG00000017291.1|UniProtKB=W5NL87 W5NL87 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 14A ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006041.1|UniProtKB=W5MFY5 W5MFY5 PTHR12011:SF285 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G3 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010613.1|UniProtKB=W5MX87 W5MX87 PTHR48051:SF49 FAMILY NOT NAMED LEUCINE-RICH REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002268.1|UniProtKB=W5M2N7 W5M2N7 PTHR19424:SF0 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to heat#GO:0034605;heat acclimation#GO:0010286;response to heat#GO:0009408;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000860.1|UniProtKB=W5LXV4 W5LXV4 PTHR11931:SF11 PHOSPHOGLYCERATE MUTASE BISPHOSPHOGLYCERATE MUTASE phosphoglycerate mutase activity#GO:0004619;isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868 nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 isomerase#PC00135;mutase#PC00160 Glycolysis#P00024>Phosphoglyceromutase#P00680 LEPOC|Ensembl=ENSLOCG00000008227.1|UniProtKB=W5MNM7 W5MNM7 PTHR23311:SF5 HEAT SHOCK REGULATED 2 CENTROSOMAL PROTEIN OF 72 KDA LEPOC|Ensembl=ENSLOCG00000004644.1|UniProtKB=W5MB39 W5MB39 PTHR24257:SF31 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER ELASTASE 3 LIKE ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015328.1|UniProtKB=W5NE01 W5NE01 PTHR13518:SF1 PUTATIVE TREBLE-CLEF ZINC-FINGER C2ORF42 FAMILY MEMBER RGD1306746 PROTEIN cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015298.1|UniProtKB=W5NDW3 W5NDW3 PTHR14150:SF12 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 UTP14A SMALL SUBUNIT PROCESSOME COMPONENT enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017632.1|UniProtKB=W5NM78 W5NM78 PTHR16736:SF3 CORTEXIN-1-RELATED CORTEXIN-1 LEPOC|Ensembl=ENSLOCG00000005248.1|UniProtKB=W5MD65 W5MD65 PTHR11675:SF123 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000002129.1|UniProtKB=W5M266 W5M266 PTHR12209:SF0 NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE EKC_KEOPS COMPLEX SUBUNIT TP53RK phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000015317.1|UniProtKB=W5NDY8 W5NDY8 PTHR12228:SF0 TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 7 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 LEPOC|Ensembl=ENSLOCG00000016428.1|UniProtKB=W5NI32 W5NI32 PTHR11475:SF60 OXIDASE/PEROXIDASE THYROID PEROXIDASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 regulation of biological quality#GO:0065008;metabolic process#GO:0008152;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;phenol-containing compound metabolic process#GO:0018958 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000006982.1|UniProtKB=W5MJ89 W5MJ89 PTHR14254:SF6 GENE 33 POLYPEPTIDE ACTIVATED CDC42 KINASE 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000007212.1|UniProtKB=W5MK16 W5MK16 PTHR10177:SF62 CYCLINS CYCLIN-J cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;transferase complex#GO:1990234;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000000531.1|UniProtKB=W5LWT0 W5LWT0 PTHR25952:SF256 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000018179.1|UniProtKB=W5NNS1 W5NNS1 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012869.1|UniProtKB=W5N5D5 W5N5D5 PTHR45677:SF14 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 3 lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 synapse#GO:0045202;presynaptic active zone#GO:0048786;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;presynapse#GO:0098793 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 LEPOC|Ensembl=ENSLOCG00000009520.1|UniProtKB=W5MTC5 W5MTC5 PTHR10558:SF2 SOMATOSTATIN SOMATOSTATIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001927.1|UniProtKB=W5M1I9 W5M1I9 PTHR17271:SF9 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN MYOSIN PHOSPHATASE RHO-INTERACTING PROTEIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000016331.1|UniProtKB=W5NHQ4 W5NHQ4 PTHR43157:SF79 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED GPI ETHANOLAMINE PHOSPHATE TRANSFERASE, STABILIZING SUBUNIT metabolic process#GO:0008152;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;phospholipid metabolic process#GO:0006644 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000006958.1|UniProtKB=W5MJ63 W5MJ63 PTHR45729:SF11 RABPHILIN, ISOFORM A DOUBLE C2-LIKE DOMAINS, GAMMA ISOFORM X1 chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;localization#GO:0051179;regulation of secretion#GO:0051046;cell communication#GO:0007154;secretion#GO:0046903;regulation of exocytosis#GO:0017157;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;export from cell#GO:0140352;signaling#GO:0023052;positive regulation of secretion#GO:0051047;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;regulated exocytosis#GO:0045055;vesicle-mediated transport in synapse#GO:0099003;positive regulation of vesicle fusion#GO:0031340;regulation of localization#GO:0032879;exocytosis#GO:0006887;regulation of transport#GO:0051049 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 LEPOC|Ensembl=ENSLOCG00000004310.1|UniProtKB=W5M9U3 W5M9U3 PTHR24416:SF356 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 multicellular organismal process#GO:0032501;cell migration#GO:0016477;biological regulation#GO:0065007;hemopoiesis#GO:0030097;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell motility#GO:0048870;regulation of cellular process#GO:0050794;leukocyte activation#GO:0045321;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cytokine-mediated signaling pathway#GO:0019221;cell activation#GO:0001775;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;lymphocyte differentiation#GO:0030098;response to chemical#GO:0042221;response to cytokine#GO:0034097;lymphocyte activation#GO:0046649;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;B cell activation#GO:0042113;cell surface receptor signaling pathway#GO:0007166;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;leukocyte differentiation#GO:0002521;positive regulation of cell population proliferation#GO:0008284;mononuclear cell differentiation#GO:1903131;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to peptide#GO:1901652;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013782.1|UniProtKB=W5N8P2 W5N8P2 PTHR10075:SF123 BASIGIN RELATED IMMUNOGLOBULIN SUPERFAMILY DCC SUBCLASS MEMBER 3 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001105.1|UniProtKB=W5LYP3 W5LYP3 PTHR22807:SF4 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098 ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;positive regulation of protein metabolic process#GO:0051247;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;methylation#GO:0032259;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;rRNA modification#GO:0000154;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;regulation of protein metabolic process#GO:0051246;cellular component biogenesis#GO:0044085;rRNA base methylation#GO:0070475;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA processing#GO:0006396;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;positive regulation of biosynthetic process#GO:0009891;rRNA processing#GO:0006364;positive regulation of translation#GO:0045727;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;post-transcriptional regulation of gene expression#GO:0010608;rRNA metabolic process#GO:0016072;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000017587.1|UniProtKB=W5NM33 W5NM33 PTHR23334:SF69 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN GAMMA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011382.1|UniProtKB=W5N044 W5N044 PTHR21444:SF17 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 STIMULATED BY RETINOIC ACID GENE 6 PROTEIN-LIKE localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;vitamin transport#GO:0051180;macromolecule localization#GO:0033036;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000012760.1|UniProtKB=W5N4Z4 W5N4Z4 PTHR24056:SF126 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 12 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011490.1|UniProtKB=W5N0G4 W5N0G4 PTHR21324:SF10 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 2 multicellular organismal-level homeostasis#GO:0048871;regulation of catabolic process#GO:0009894;tissue homeostasis#GO:0001894;retina homeostasis#GO:0001895;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of autophagy#GO:0010506;homeostatic process#GO:0042592;biological regulation#GO:0065007;anatomical structure homeostasis#GO:0060249;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015256.1|UniProtKB=W5NDR6 W5NDR6 PTHR45697:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 guanyl nucleotide binding#GO:0019001;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001827.1|UniProtKB=W5M157 W5M157 PTHR11438:SF4 PROENKEPHALIN PROENKEPHALIN-B signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;sensory perception of pain#GO:0019233;neuropeptide signaling pathway#GO:0007218;system process#GO:0003008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987 secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell body#GO:0044297;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle lumen#GO:0043233;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane-enclosed lumen#GO:0031974;secretory vesicle#GO:0099503 intercellular signal molecule#PC00207;neuropeptide#PC00162;peptide hormone#PC00179 Enkephalin release#P05913>Enkephalin#P05976;Opioid prodynorphin pathway#P05916>prodynorphin#P05997;Opioid prodynorphin pathway#P05916>dynorphin#P06003;Enkephalin release#P05913>preproenkephalin#G06045;Enkephalin release#P05913>preproenkephalin mRNA#G06046;Opioid prodynorphin pathway#P05916>preprodynorphin#G06049;Opioid proenkephalin pathway#P05915>Enkephalin#P05991;Opioid prodynorphin pathway#P05916>preprodynorphin#G06047 LEPOC|Ensembl=ENSLOCG00000013697.1|UniProtKB=W5N8D5 W5N8D5 ENTREP2 PTHR17615:SF6 PROTEIN FAM189A PROTEIN ENTREP2 LEPOC|Ensembl=ENSLOCG00000003992.1|UniProtKB=W5M8S1 W5M8S1 PTHR12156:SF21 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 2 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;basal part of cell#GO:0045178;cell periphery#GO:0071944;cell cortex#GO:0005938 EGF receptor signaling pathway#P00018>Gab#P00563 LEPOC|Ensembl=ENSLOCG00000014019.1|UniProtKB=W5N9H2 W5N9H2 PTHR12137:SF68 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 14 catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009141.1|UniProtKB=W5MRY5 W5MRY5 PTHR11346:SF190 GALECTIN GALECTIN binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000001979.1|UniProtKB=W5M1N3 W5M1N3 PTHR31258:SF5 KERATINOCYTE-ASSOCIATED PROTEIN 3 TMEM54 PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000003987.1|UniProtKB=W5M8T7 W5M8T7 PTHR43184:SF11 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A1 phosphate transmembrane transporter activity#GO:0005315;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;organophosphate ester transport#GO:0015748;phosphate ion transport#GO:0006817 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001874.1|UniProtKB=W5M1C3 W5M1C3 PTHR10794:SF50 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PHOSPHOLIPASE ABHD3 hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;A2-type glycerophospholipase activity#GO:0004623;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity#GO:0016787 organophosphate metabolic process#GO:0019637;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine metabolic process#GO:0046470;lipid biosynthetic process#GO:0008610;monocarboxylic acid catabolic process#GO:0072329;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;phospholipid metabolic process#GO:0006644;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000016065.1|UniProtKB=W5NGN5 W5NGN5 PTHR10513:SF8 DEOXYNUCLEOSIDE KINASE DEOXYGUANOSINE KINASE, MITOCHONDRIAL transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;deoxynucleoside kinase activity#GO:0019136;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011759.1|UniProtKB=W5N1F0 W5N1F0 ELOVL6 PTHR11157:SF125 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 6 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016175.1|UniProtKB=W5NH26 W5NH26 PTHR12756:SF12 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE-LIKE PROTEIN 5 exopeptidase activity#GO:0008238;protein binding#GO:0005515;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;binding#GO:0005488;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;metalloexopeptidase activity#GO:0008235 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000007783.1|UniProtKB=W5MM49 W5MM49 PTHR22619:SF3 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 6 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000001711.1|UniProtKB=W5M0R8 W5M0R8 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000615.1|UniProtKB=W5LX19 W5LX19 PTHR19956:SF5 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2 structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intermediate filament#GO:0005882;organelle envelope#GO:0031967;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000008276.1|UniProtKB=W5MNU2 W5MNU2 PTHR21181:SF13 ER membrane protein complex subunit 5-related NADH DEHYDROGENASE (UBIQUINONE) COMPLEX I, ASSEMBLY FACTOR 6 LEPOC|Ensembl=ENSLOCG00000018101.1|UniProtKB=W5NNJ3 W5NNJ3 PTHR12137:SF4 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 12 transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000010377.1|UniProtKB=W5MWF9 W5MWF9 PTHR18902:SF25 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000018217.1|UniProtKB=W5NNV9 W5NNV9 PTHR24231:SF17 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled receptor binding#GO:0001664;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor binding#GO:0005102 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003786.1|UniProtKB=W5M804 W5M804 PTHR12468:SF2 GPI MANNOSYLTRANSFERASE 2 GPI ALPHA-1,6-MANNOSYLTRANSFERASE 2 glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;organophosphate metabolic process#GO:0019637;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;phospholipid metabolic process#GO:0006644 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;mannosyltransferase complex#GO:0031501;membrane#GO:0016020;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012984.1|UniProtKB=W5N5T4 W5N5T4 PTHR21705:SF10 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK INTERACTING PROTEIN 2A LEPOC|Ensembl=ENSLOCG00000011316.1|UniProtKB=W5MZV0 W5MZV0 PTHR24028:SF264 CADHERIN-87A PROTOCADHERIN 1 GAMMA 32 cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000017763.1|UniProtKB=W5NMK8 W5NMK8 PTHR17068:SF3 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER HOMOLOG LEPOC|Ensembl=ENSLOCG00000006452.1|UniProtKB=W5MHD7 W5MHD7 PTHR11176:SF4 BOULE-RELATED DELETED IN AZOOSPERMIA-LIKE translation regulator activity#GO:0045182 regulation of RNA stability#GO:0043487;positive regulation of translation#GO:0045727;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA catabolic process#GO:1902369;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of translational initiation#GO:0006446;positive regulation of protein metabolic process#GO:0051247;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005899.1|UniProtKB=W5MFG9 W5MFG9 PTHR23330:SF8 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED JUNCTION-MEDIATING AND -REGULATORY PROTEIN transcription coregulator activity#GO:0003712;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;protein-containing complex binding#GO:0044877 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;regulation of cellular process#GO:0050794;actin filament organization#GO:0007015;apoptotic signaling pathway#GO:0097190;positive regulation of cellular process#GO:0048522;Arp2/3 complex-mediated actin nucleation#GO:0034314;biological regulation#GO:0065007;signal transduction by p53 class mediator#GO:0072331;intrinsic apoptotic signaling pathway#GO:0097193;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;signaling#GO:0023052;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003518.1|UniProtKB=W5M703 W5M703 PTHR10969:SF15 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEIN 1 LIGHT CHAIN 3 BETA-RELATED ubiquitin protein ligase binding#GO:0031625;phospholipid binding#GO:0005543;ubiquitin-like protein ligase binding#GO:0044389;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515;lipid binding#GO:0008289;microtubule binding#GO:0008017;binding#GO:0005488;enzyme binding#GO:0019899 cellular response to stress#GO:0033554;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;protein-containing complex disassembly#GO:0032984;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to nutrient levels#GO:0031669;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;cellular component assembly#GO:0022607 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;autophagosome membrane#GO:0000421;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;autophagosome#GO:0005776 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000016312.1|UniProtKB=W5NHN2 W5NHN2 PTHR12587:SF6 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular component organization#GO:0016043;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;presynaptic active zone#GO:0048786;presynapse#GO:0098793 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002975.1|UniProtKB=W5M568 W5M568 PTHR14963:SF5 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 28 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of stress fiber assembly#GO:0051492;negative regulation of cytoskeleton organization#GO:0051494;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of actin filament bundle assembly#GO:0032231;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;regulation of intracellular signal transduction#GO:1902531;regulation of actin filament length#GO:0030832;regulation of signaling#GO:0023051;regulation of biological quality#GO:0065008;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000009210.1|UniProtKB=W5MS71 W5MS71 PTHR11545:SF45 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of translation#GO:0017148;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000005900.1|UniProtKB=W5MFH1 W5MFH1 PTHR14339:SF10 VASCULIN VASCULIN-LIKE PROTEIN 1 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000014002.1|UniProtKB=W5N9F4 W5N9F4 PTHR10545:SF66 DIAMINE N-ACETYLTRANSFERASE DIAMINE ACETYLTRANSFERASE 2A-RELATED N-acetyltransferase activity#GO:0008080;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 transferase#PC00220;acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000011620.1|UniProtKB=W5N0W9 W5N0W9 PTHR24366:SF150 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 3 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000016344.1|UniProtKB=W5NHS0 W5NHS0 PTHR15286:SF17 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 9 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004214.1|UniProtKB=W5M9I0 W5M9I0 PTHR31247:SF17 TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER TRANSMEMBRANE PROTEIN 198 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000010936.1|UniProtKB=W5MYF3 W5MYF3 PTHR45998:SF9 SERINE/THREONINE-PROTEIN KINASE 16 SERINE_THREONINE-PROTEIN KINASE 16 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011288.1|UniProtKB=W5MZR4 W5MZR4 PTHR10122:SF11 CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 organelle membrane#GO:0031090;transporter complex#GO:1990351;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;transmembrane transporter complex#GO:1902495;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000007703.1|UniProtKB=W5MLU7 W5MLU7 PTHR12442:SF37 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;microtubule-based movement#GO:0007018;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;microtubule-based transport#GO:0099111;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport along microtubule#GO:0010970;localization#GO:0051179 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000003320.1|UniProtKB=W5M6B2 W5M6B2 PTHR46473:SF4 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 38 transmembrane transporter activity#GO:0022857;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;molecular function regulator activity#GO:0098772;monoatomic cation channel activity#GO:0005261;transmembrane transporter binding#GO:0044325;transporter regulator activity#GO:0141108;potassium channel activity#GO:0005267;channel regulator activity#GO:0016247;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;potassium channel regulator activity#GO:0015459;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;binding#GO:0005488;molecular function activator activity#GO:0140677;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;protein binding#GO:0005515 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000003592.1|UniProtKB=W5M799 W5M799 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception of light stimulus#GO:0050953 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008781.1|UniProtKB=W5MQN2 W5MQN2 PTHR11735:SF6 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012910.1|UniProtKB=W5N5I5 W5N5I5 PTHR24365:SF23 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 10 protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;lipid binding#GO:0008289;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;immune system process#GO:0002376;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;toll-like receptor signaling pathway#GO:0002224;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;cell communication#GO:0007154;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000000978.1|UniProtKB=W5LY90 W5LY90 PTHR31872:SF6 TRANSMEMBRANE PROTEIN 179 TRANSMEMBRANE PROTEIN 179-LIKE LEPOC|Ensembl=ENSLOCG00000017460.1|UniProtKB=W5NLQ6 W5NLQ6 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011404.1|UniProtKB=W5N060 W5N060 PTHR23419:SF1 DIVALENT CATION TOLERANCE CUTA-RELATED PROTEIN CUTA small molecule binding#GO:0036094;binding#GO:0005488;copper ion binding#GO:0005507;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000007568.1|UniProtKB=W5MLF6 W5MLF6 PTHR11199:SF6 STROMAL ANTIGEN COHESIN SUBUNIT SA-1 chromatin binding#GO:0003682;binding#GO:0005488 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004108.1|UniProtKB=W5M959 W5M959 PTHR13600:SF34 LEUCINE CARBOXYL METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4 O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000007944.1|UniProtKB=W5MMP5 W5MMP5 PTHR12341:SF7 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 1 binding#GO:0005488;nucleic acid binding#GO:0003676;exonuclease activity#GO:0004527;RNA binding#GO:0003723;hydrolase activity#GO:0016787;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 LEPOC|Ensembl=ENSLOCG00000008897.1|UniProtKB=W5MR24 W5MR24 PTHR10677:SF21 UBIQUILIN UBIQUILIN-4 protein binding#GO:0005515;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003986.1|UniProtKB=W5M8Q1 W5M8Q1 PTHR15228:SF22 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 22 GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of biological quality#GO:0065008;negative regulation of cell communication#GO:0010648;regulation of synapse structure or activity#GO:0050803;negative regulation of intracellular signal transduction#GO:1902532 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000016071.1|UniProtKB=W5NGP3 W5NGP3 PTHR48078:SF14 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED L-THREONINE AMMONIA-LYASE-RELATED catalytic activity#GO:0003824;lyase activity#GO:0016829 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000004678.1|UniProtKB=W5MB45 W5MB45 PTHR14568:SF9 TRANSMEMBRANE SUPERFAMILY 6 MEMBER 1/2 TRANSMEMBRANE 6 SUPERFAMILY MEMBER 2 biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;lipid homeostasis#GO:0055088;chemical homeostasis#GO:0048878;regulation of lipid metabolic process#GO:0019216 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000005392.1|UniProtKB=W5MDP1 W5MDP1 PTHR11348:SF18 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;signaling receptor binding#GO:0005102;integrin binding#GO:0005178;carbohydrate derivative binding#GO:0097367;cell adhesion molecule binding#GO:0050839;heparin binding#GO:0008201 positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of developmental process#GO:0050793;cell adhesion#GO:0007155;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of locomotion#GO:0040017 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015204.1|UniProtKB=W5NDK1 W5NDK1 PTHR46756:SF27 TRANSGELIN GAS2-LIKE PROTEIN 3 ISOFORM X1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015 supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000001838.1|UniProtKB=W5M172 W5M172 PTHR11852:SF1 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT ALPHA2 transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 spermatogenesis#GO:0007283;developmental process#GO:0032502;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;gamete generation#GO:0007276;male gamete generation#GO:0048232 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009072.1|UniProtKB=W5MRQ5 W5MRQ5 PTHR24203:SF14 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 10 LEPOC|Ensembl=ENSLOCG00000008252.1|UniProtKB=W5MNQ8 W5MNQ8 PTHR12663:SF1 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED SISTER CHROMATID COHESION PROTEIN PDS5 HOMOLOG B chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016350.1|UniProtKB=W5NHT3 W5NHT3 PTHR31219:SF2 CHROMOSOME 28 C12ORF29 HOMOLOG RNA LIGASE 1 LEPOC|Ensembl=ENSLOCG00000012214.1|UniProtKB=W5N358 W5N358 PTHR45836:SF9 SLIT HOMOLOG SLIT HOMOLOG 3 PROTEIN protein binding#GO:0005515;heparin binding#GO:0008201;signaling receptor binding#GO:0005102;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539 plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;taxis#GO:0042330;response to chemical#GO:0042221;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;chemotaxis#GO:0006935;system development#GO:0048731;anatomical structure development#GO:0048856;locomotion#GO:0040011 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 LEPOC|Ensembl=ENSLOCG00000012688.1|UniProtKB=W5N4Q1 W5N4Q1 PTHR12011:SF476 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G3-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002693.1|UniProtKB=W5M453 W5M453 PTHR11537:SF65 VOLTAGE-GATED POTASSIUM CHANNEL BTB DOMAIN-CONTAINING PROTEIN potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000012824.1|UniProtKB=W5N572 W5N572 PTHR17600:SF2 MESODERM DEVELOPMENT CANDIDATE 2 LRP CHAPERONE MESD LEPOC|Ensembl=ENSLOCG00000008441.1|UniProtKB=W5MPH1 W5MPH1 PTHR46735:SF5 CALPAIN, SMALL SUBUNIT 1 A-RELATED GRANCALCIN metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 LEPOC|Ensembl=ENSLOCG00000010605.1|UniProtKB=W5MX82 W5MX82 PTHR34533:SF3 TRANSMEMBRANE PROTEIN CCDC163 BICD FAMILY-LIKE CARGO ADAPTER 2 LEPOC|Ensembl=ENSLOCG00000006671.1|UniProtKB=W5MI65 W5MI65 PTHR13817:SF54 TITIN CELL ADHESION MOLECULE DSCAML1 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000001192.1|UniProtKB=W5LYZ7 W5LYZ7 PTHR45652:SF5 GLIAL FIBRILLARY ACIDIC PROTEIN VIMENTIN structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;intermediate filament organization#GO:0045109;intermediate filament cytoskeleton organization#GO:0045104;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;axon#GO:0030424;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 intermediate filament#PC00129;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000004197.1|UniProtKB=W5M9F8 W5M9F8 PTHR10361:SF55 SODIUM-BILE ACID COTRANSPORTER SODIUM-DEPENDENT ORGANIC ANION TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;bile acid transmembrane transporter activity#GO:0015125 monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;localization#GO:0051179;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;bile acid and bile salt transport#GO:0015721;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000008280.1|UniProtKB=W5MNU8 W5MNU8 PTHR14002:SF38 ENDOGLIN/TGF-BETA RECEPTOR TYPE III CUB AND ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010177.1|UniProtKB=W5MVQ0 W5MVQ0 PTHR11360:SF92 MONOCARBOXYLATE TRANSPORTER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011036.1|UniProtKB=W5MYV5 W5MYV5 PTHR46806:SF2 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN NEUROPILIN-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;plasma membrane region#GO:0098590;synaptic membrane#GO:0097060;axon#GO:0030424;postsynaptic membrane#GO:0045211;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000016184.1|UniProtKB=W5NH39 W5NH39 PTHR11132:SF250 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E3 organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017821.1|UniProtKB=W5NMR5 W5NMR5 PTHR26451:SF887 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 4K15-LIKE molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014607.1|UniProtKB=W5NBG8 W5NBG8 PTHR11451:SF51 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE 1, CYTOPLASMIC ISOFORM X1 ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000010487.1|UniProtKB=W5MWV1 W5MWV1 PTHR45971:SF2 PHOX (PX) DOMAIN-CONTAINING PROTEIN PROTEIN ASSOCIATED WITH UVRAG AS AUTOPHAGY ENHANCER phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;vesicle fusion#GO:0006906;catabolic process#GO:0009056;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;localization#GO:0051179;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;macroautophagy#GO:0016236;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;transport#GO:0006810;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;autophagosome membrane#GO:0000421;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;autophagosome#GO:0005776;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000004103.1|UniProtKB=W5M939 W5M939 PTHR25466:SF21 T-LYMPHOCYTE ACTIVATION ANTIGEN BUTYROPHILIN SUBFAMILY 2 MEMBER A1-LIKE-RELATED receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008206.1|UniProtKB=W5MNK2 W5MNK2 PTHR46784:SF1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY B MEMBER 1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY B MEMBER 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to biotic stimulus#GO:0002831;regulation of natural killer cell mediated immunity#GO:0002715;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of immune effector process#GO:0002697;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of lymphocyte mediated immunity#GO:0002706;regulation of defense response#GO:0031347;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;regulation of response to external stimulus#GO:0032101;regulation of natural killer cell mediated cytotoxicity#GO:0042269;biological regulation#GO:0065007;regulation of innate immune response#GO:0045088;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001520.1|UniProtKB=W5M024 W5M024 PTHR47743:SF1 KIAA1210 / KIAA1211 FAMILY MEMBER CRACD-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000010975.1|UniProtKB=W5MYK3 W5MYK3 PTHR10366:SF876 NAD DEPENDENT EPIMERASE/DEHYDRATASE 3 BETA-HYDROXYSTEROID DEHYDROGENASE_DELTA 5--4-ISOMERASE TYPE 2-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 lyase#PC00144;dehydratase#PC00091;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000017645.1|UniProtKB=W5NM91 W5NM91 PTHR26450:SF44 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51M1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014124.1|UniProtKB=W5N9T9 W5N9T9 PTHR28585:SF1 TUBEROINFUNDIBULAR PEPTIDE OF 39 RESIDUES TUBEROINFUNDIBULAR PEPTIDE OF 39 RESIDUES LEPOC|Ensembl=ENSLOCG00000014035.1|UniProtKB=W5N9J5 W5N9J5 PTHR13104:SF0 MED-6-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 6 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000017178.1|UniProtKB=W5NKS2 W5NKS2 PTHR11003:SF241 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 5 gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000004709.1|UniProtKB=W5MBB0 W5MBB0 PTHR45614:SF9 MYB PROTEIN-RELATED MYB-RELATED PROTEIN A nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell cycle#GO:0007049;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;mitotic cell cycle#GO:0000278;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000009777.1|UniProtKB=W5MU84 W5MU84 PTHR44666:SF1 WD REPEAT-CONTAINING PROTEIN 53 WD REPEAT-CONTAINING PROTEIN 53 LEPOC|Ensembl=ENSLOCG00000005543.1|UniProtKB=W5ME82 W5ME82 PTHR16024:SF16 XK-RELATED PROTEIN XK-RELATED PROTEIN 4 localization#GO:0051179;anatomical structure development#GO:0048856;cell death#GO:0008219;programmed cell death#GO:0012501;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;developmental process#GO:0032502;transport#GO:0006810;phagocytosis#GO:0006909;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cellular component organization#GO:0016043;endocytosis#GO:0006897;membrane invagination#GO:0010324;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;import into cell#GO:0098657;cellular process#GO:0009987;endomembrane system organization#GO:0010256 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000016746.1|UniProtKB=W5NJ86 W5NJ86 PTHR11232:SF81 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PID DOMAIN-CONTAINING PROTEIN signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014416.1|UniProtKB=W5NAT9 W5NAT9 PTHR14085:SF3 WD-REPEAT PROTEIN BING4 WD REPEAT-CONTAINING PROTEIN 46 gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000008190.1|UniProtKB=W5MNI4 W5MNI4 PTHR31054:SF5 ZYGOTE ARREST PROTEIN 1-LIKE ISOFORM X1 PROTEIN ZAR1-LIKE mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 negative regulation of metabolic process#GO:0009892;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of translation#GO:0017148;oogenesis#GO:0048477;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;negative regulation of protein metabolic process#GO:0051248;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure maturation#GO:0071695;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;developmental maturation#GO:0021700;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell maturation#GO:0048469;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009216.1|UniProtKB=W5MS82 W5MS82 PTHR45622:SF73 UBIQUITIN-PROTEIN LIGASE E3A-RELATED HECT DOMAIN-CONTAINING PROTEIN ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013118.1|UniProtKB=W5N6A4 W5N6A4 PTHR23122:SF35 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 2 anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010859.1|UniProtKB=W5MY48 W5MY48 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000000904.1|UniProtKB=W5LXZ8 W5LXZ8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007725.1|UniProtKB=W5MLX0 W5MLX0 PTHR10106:SF12 CYTOCHROME B561-RELATED PLASMA MEMBRANE ASCORBATE-DEPENDENT REDUCTASE CYBRD1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491 carbohydrate homeostasis#GO:0033500;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 cellular anatomical structure#GO:0110165;brush border membrane#GO:0031526;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;brush border#GO:0005903;cell projection membrane#GO:0031253;cluster of actin-based cell projections#GO:0098862;apical part of cell#GO:0045177 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000017746.1|UniProtKB=W5NMJ1 W5NMJ1 PTHR15895:SF12 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 5 PROTEIN LEPOC|Ensembl=ENSLOCG00000012652.1|UniProtKB=W5N4L2 W5N4L2 PTHR12173:SF1 GDNF SUBFAMILY OF TGF-BETA FAMILY GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545 signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;growth factor#PC00112;neurotrophic factor#PC00163 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000006281.1|UniProtKB=W5MGU7 W5MGU7 PTHR13817:SF20 TITIN MYOSIN-BINDING PROTEIN C, CARDIAC-TYPE structural molecule activity#GO:0005198 organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;system development#GO:0048731;supramolecular fiber organization#GO:0097435;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;heart morphogenesis#GO:0003007;animal organ morphogenesis#GO:0009887;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;cardiac muscle tissue development#GO:0048738;cellular developmental process#GO:0048869;multicellular organismal process#GO:0032501;tissue development#GO:0009888;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;circulatory system development#GO:0072359;actomyosin structure organization#GO:0031032;cell development#GO:0048468;muscle organ development#GO:0007517;cellular anatomical entity morphogenesis#GO:0032989;striated muscle tissue development#GO:0014706;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;heart development#GO:0007507;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010 contractile muscle fiber#GO:0043292;A band#GO:0031672;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;M band#GO:0031430;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;membraneless organelle#GO:0043228;sarcomere#GO:0030017 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000017639.1|UniProtKB=W5NM85 W5NM85 PTHR22639:SF13 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3-LIKE viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000014121.1|UniProtKB=W5N9U0 W5N9U0 PTHR11679:SF71 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 2 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000016386.1|UniProtKB=W5NHX6 W5NHX6 PTHR47992:SF105 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1B catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of canonical Wnt signaling pathway#GO:0060828 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000017421.1|UniProtKB=W5NLL7 W5NLL7 PTHR14527:SF2 PROTEIN MIS12 HOMOLOG PROTEIN MIS12 HOMOLOG mitotic cell cycle#GO:0000278;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;organelle fission#GO:0048285;kinetochore organization#GO:0051383;nuclear division#GO:0000280;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382;cellular component assembly#GO:0022607;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059 outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776 LEPOC|Ensembl=ENSLOCG00000013666.1|UniProtKB=W5N891 W5N891 PTHR24416:SF652 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-B RECEPTOR 4B protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 LEPOC|Ensembl=ENSLOCG00000009896.1|UniProtKB=W5MUP5 W5MUP5 PTHR45739:SF3 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1B PRECURSOR epithelial structure maintenance#GO:0010669;homeostatic process#GO:0042592;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;cellular process#GO:0009987;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000014362.1|UniProtKB=W5NAM7 W5NAM7 PTHR22838:SF4 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 13 chromatin binding#GO:0003682;binding#GO:0005488 LEPOC|Ensembl=ENSLOCG00000004752.1|UniProtKB=W5MBE8 W5MBE8 PTHR10027:SF33 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1A-RELATED transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;monoatomic ion-gated channel activity#GO:0022839;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000007765.1|UniProtKB=W5MM25 W5MM25 PTHR34093:SF1 CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253 intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000006884.1|UniProtKB=W5MIW8 W5MIW8 PTHR11339:SF384 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-2 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000002941.1|UniProtKB=W5M508 W5M508 PTHR15660:SF2 BRISC AND BRCA1-A COMPLEX MEMBER 1 BRISC AND BRCA1-A COMPLEX MEMBER 1 regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 LEPOC|Ensembl=ENSLOCG00000014250.1|UniProtKB=W5NA87 W5NA87 PTHR11040:SF120 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000014972.1|UniProtKB=W5NCS4 W5NCS4 PTHR22600:SF39 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE SUBUNIT ALPHA hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 aminoglycan metabolic process#GO:0006022;ceramide metabolic process#GO:0006672;protein metabolic process#GO:0019538;sphingolipid catabolic process#GO:0030149;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;extracellular region#GO:0005576;intracellular organelle#GO:0043229 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000006434.1|UniProtKB=W5MHB8 W5MHB8 PTHR10762:SF1 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1 metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 LEPOC|Ensembl=ENSLOCG00000004335.1|UniProtKB=W5M9W8 W5M9W8 PTHR44942:SF6 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN NOVEL PROTEIN LEPOC|Ensembl=ENSLOCG00000013997.1|UniProtKB=W5N9E3 W5N9E3 PTHR24340:SF27 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.8 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000001948.1|UniProtKB=W5M1J9 W5M1J9 PTHR10343:SF92 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2 binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 LEPOC|Ensembl=ENSLOCG00000016471.1|UniProtKB=W5NI87 W5NI87 PTHR13720:SF11 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 4 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 microtubule cytoskeleton#GO:0015630;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000003500.1|UniProtKB=W5M700 W5M700 PTHR48083:SF41 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000013190.1|UniProtKB=W5N6J2 W5N6J2 PTHR10812:SF8 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-ALPHA double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;skeletal system development#GO:0001501;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of transcription by RNA polymerase II#GO:0006357;regulation of apoptotic process#GO:0042981;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;animal organ development#GO:0048513;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;renal system development#GO:0072001;kidney development#GO:0001822;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012300.1|UniProtKB=W5N3D3 W5N3D3 PTHR24129:SF0 ANKYCORBIN ANKYCORBIN LEPOC|Ensembl=ENSLOCG00000009388.1|UniProtKB=W5MSV7 W5MSV7 PTHR23322:SF96 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 1 DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;ubiquitin binding#GO:0043130;transcription factor binding#GO:0008134;binding#GO:0005488 response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 FAS signaling pathway#P00020>FAF1#P00609 LEPOC|Ensembl=ENSLOCG00000012810.1|UniProtKB=W5N551 W5N551 PTHR18945:SF82 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-6 monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;acetylcholine receptor activity#GO:0015464;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960 modulation of chemical synaptic transmission#GO:0050804;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;chemical synaptic transmission#GO:0007268;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;establishment of localization#GO:0051234;transport#GO:0006810;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;neuromuscular synaptic transmission#GO:0007274 cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;postsynapse#GO:0098794;plasma membrane protein complex#GO:0098797 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA6#P06592;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 LEPOC|Ensembl=ENSLOCG00000007581.1|UniProtKB=W5MLE7 W5MLE7 PTHR24016:SF21 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;Golgi vesicle transport#GO:0048193;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996;retrograde transport, vesicle recycling within Golgi#GO:0000301 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;COG complex#GO:0017119;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010079.1|UniProtKB=W5MVC5 W5MVC5 PTHR10513:SF15 DEOXYNUCLEOSIDE KINASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;deoxynucleoside kinase activity#GO:0019136 mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000008182.1|UniProtKB=W5MNH5 W5MNH5 PTHR24418:SF231 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SYK catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell activation#GO:0001775;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of cell adhesion#GO:0045785;leukocyte activation#GO:0045321;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell adhesion mediated by integrin#GO:0033628;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;macrophage activation#GO:0042116;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;adaptive immune response#GO:0002250;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;cell activation involved in immune response#GO:0002263;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;leukocyte activation involved in immune response#GO:0002366;immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;B cell receptor signaling pathway#GO:0050853;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;myeloid leukocyte activation#GO:0002274;antigen receptor-mediated signaling pathway#GO:0050851 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 B cell activation#P00010>Syk#P00382 LEPOC|Ensembl=ENSLOCG00000009375.1|UniProtKB=W5MSS4 W5MSS4 PTHR11685:SF104 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF144B catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015205.1|UniProtKB=W5NDK2 W5NDK2 CIAO1 PTHR19920:SF0 WD40 PROTEIN CIAO1 CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000009671.1|UniProtKB=W5MTV7 W5MTV7 PTHR18860:SF154 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA_DELTA-RELATED scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004071.1|UniProtKB=W5M8Z9 W5M8Z9 PTHR46403:SF3 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;localization#GO:0051179;macromolecule localization#GO:0033036;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;negative regulation of apoptotic process#GO:0043066;lipid transport#GO:0006869;phospholipid transport#GO:0015914;biological regulation#GO:0065007;intermembrane phospholipid transfer#GO:0120010;membrane organization#GO:0061024;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;transport#GO:0006810;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;cellular component organization or biogenesis#GO:0071840 mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000007913.1|UniProtKB=W5MMK3 W5MMK3 PTHR10276:SF3 CORE-BINDING FACTOR, BETA SUBUNIT CORE-BINDING FACTOR SUBUNIT BETA transcription coactivator activity#GO:0003713;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;transcription coregulator activity#GO:0003712;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000007362.1|UniProtKB=W5MKL5 W5MKL5 PTHR12622:SF47 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004633.1|UniProtKB=W5MAZ2 W5MAZ2 PTHR12901:SF8 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG A, MITOCHONDRIAL intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000007921.1|UniProtKB=W5MML5 W5MML5 PTHR21534:SF0 KATANIN-INTERACTING PROTEIN KATANIN-INTERACTING PROTEIN LEPOC|Ensembl=ENSLOCG00000002443.1|UniProtKB=W5M3B3 W5M3B3 PTHR46582:SF1 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 LEPOC|Ensembl=ENSLOCG00000015794.1|UniProtKB=W5NFN3 W5NFN3 PTHR24247:SF212 5-HYDROXYTRYPTAMINE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013400.1|UniProtKB=W5N7B1 W5N7B1 PTHR13622:SF14 THIAMIN PYROPHOSPHOKINASE THIAMINE PYROPHOSPHOKINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;transferase#PC00220 Thiamin metabolism#P02780>Thiamine kinase#P03176 LEPOC|Ensembl=ENSLOCG00000009019.1|UniProtKB=W5MRI1 W5MRI1 PTHR15955:SF8 RWD DOMAIN CONTAINING PROTEIN 2 RWD DOMAIN-CONTAINING PROTEIN 2B ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012282.1|UniProtKB=W5N3B2 W5N3B2 PTHR10160:SF22 NAD(P) TRANSHYDROGENASE NAD(P) TRANSHYDROGENASE, MITOCHONDRIAL nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000016235.1|UniProtKB=W5NHB5 W5NHB5 PTHR10983:SF8 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DELTA acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000000246.1|UniProtKB=W5LVX1 W5LVX1 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000005968.1|UniProtKB=W5MFR2 W5MFR2 PTHR47448:SF3 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000009069.1|UniProtKB=W5MRQ1 W5MRQ1 PTHR13844:SF5 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 3 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000007060.1|UniProtKB=W5MJI9 W5MJI9 PTHR23063:SF21 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 transferase#PC00220;acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012267.1|UniProtKB=W5N3A0 W5N3A0 PTHR15597:SF25 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 3 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;nervous system development#GO:0007399;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011552.1|UniProtKB=W5N0N6 W5N0N6 PTHR32510:SF3 TRANSMEMBRANE PROTEIN 98 TRANSMEMBRANE PROTEIN 98 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000005006.1|UniProtKB=W5MCB7 W5MCB7 PTHR32074:SF2 RNA DEMETHYLASE ALKBH5 RNA DEMETHYLASE ALKBH5 dioxygenase activity#GO:0051213;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on RNA#GO:0140098 regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membraneless organelle#GO:0043228 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000017272.1|UniProtKB=W5NL55 W5NL55 PTHR20859:SF98 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON GAMMA RECEPTOR 2 PRECURSOR-RELATED cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001669.1|UniProtKB=W5M0M7 W5M0M7 PTHR22763:SF164 RING ZINC FINGER PROTEIN RING FINGER PROTEIN 145 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008740.1|UniProtKB=W5MQI5 W5MQI5 PTHR14593:SF5 WD REPEAT-CONTAINING PROTEIN 11 WD REPEAT-CONTAINING PROTEIN 11 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000005276.1|UniProtKB=W5MDA0 W5MDA0 PTHR22883:SF466 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC4 acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007497.1|UniProtKB=W5ML41 W5ML41 PTHR31774:SF1 PROTEIN SHISA-9-RELATED PROTEIN SHISA-9 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of synaptic plasticity#GO:0048167;regulation of signaling#GO:0023051;regulation of neuronal synaptic plasticity#GO:0048168;regulation of biological quality#GO:0065008 asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;neuron spine#GO:0044309;cell projection#GO:0042995;postsynapse#GO:0098794;dendritic spine#GO:0043197;cell projection membrane#GO:0031253;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256;protein-containing complex#GO:0032991;cell leading edge#GO:0031252;neuron projection#GO:0043005;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060 LEPOC|Ensembl=ENSLOCG00000005687.1|UniProtKB=W5MEQ8 W5MEQ8 PTHR28448:SF1 UPF0728 PROTEIN C10ORF53 UPF0728 PROTEIN C10ORF53 LEPOC|Ensembl=ENSLOCG00000007004.1|UniProtKB=W5MJB9 W5MJB9 PTHR45752:SF13 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 58 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005341.1|UniProtKB=W5MDH5 W5MDH5 PTHR11438:SF3 PROENKEPHALIN PROENKEPHALIN-A molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;sensory perception of pain#GO:0019233;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 membrane-enclosed lumen#GO:0031974;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;cell body#GO:0044297;organelle lumen#GO:0043233;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;organelle#GO:0043226 peptide hormone#PC00179;neuropeptide#PC00162;intercellular signal molecule#PC00207 Opioid proenkephalin pathway#P05915>proenkephalin#P05995;Opioid proenkephalin pathway#P05915>Enkephalin#P05991;Enkephalin release#P05913>preproenkephalin mRNA#G06046;Enkephalin release#P05913>preproenkephalin#G06045;Opioid proenkephalin pathway#P05915>peptide F#P05987;Opioid proenkephalin pathway#P05915>leu-Enkephalin#P05989;Enkephalin release#P05913>Enkephalin#P05976;Opioid proenkephalin pathway#P05915>met-Enkephalin#P05992;Opioid proenkephalin pathway#P05915>peptide E#P05988 LEPOC|Ensembl=ENSLOCG00000001155.1|UniProtKB=W5LYY1 W5LYY1 PTHR10407:SF14 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN-INTERACTING PROTEIN 1 phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;cytoskeletal adaptor activity#GO:0008093;protein binding#GO:0005515;protein-membrane adaptor activity#GO:0043495;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;regulation of apoptotic process#GO:0042981;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;endocytosis#GO:0006897;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;transport#GO:0006810;actin filament organization#GO:0007015;establishment of localization#GO:0051234;regulation of ERBB signaling pathway#GO:1901184;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;localization#GO:0051179 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;vesicle#GO:0031982;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;presynapse#GO:0098793;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;clathrin-coated vesicle#GO:0030136 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 Huntington disease#P00029>Hip-1#P00765 LEPOC|Ensembl=ENSLOCG00000000391.1|UniProtKB=W5LWB8 W5LWB8 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000004615.1|UniProtKB=W5MAX1 W5MAX1 PTHR11208:SF131 RNA-BINDING PROTEIN RELATED PROTEIN QUAKING-A RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of mRNA processing#GO:0050684;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000007706.1|UniProtKB=W5MLU3 W5MLU3 PTHR19818:SF141 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008504.1|UniProtKB=W5MPN8 W5MPN8 PTHR11866:SF3 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP1 SUBTYPE molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;regulation of biological quality#GO:0065008;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 PI3 kinase pathway#P00048>GPCR#P01204;Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 LEPOC|Ensembl=ENSLOCG00000010171.1|UniProtKB=W5MVN9 W5MVN9 PTHR31120:SF8 METALLOPROTEASE TIKI METALLOPROTEASE TIKI2 binding#GO:0005488;protein binding#GO:0005515;Wnt-protein binding#GO:0017147 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signal transduction#GO:0009968;regulation of cellular process#GO:0050794;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523 organelle membrane#GO:0031090;plasma membrane#GO:0005886;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000008049.1|UniProtKB=W5MN16 W5MN16 PTHR21634:SF11 RE13835P FOLLICULIN-INTERACTING PROTEIN 2 protein binding#GO:0005515;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011033.1|UniProtKB=W5MYS8 W5MYS8 PTHR11860:SF96 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IG-LIKE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008532.1|UniProtKB=W5MPS3 W5MPS3 PTHR11383:SF3 NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 13 NAD(P)H PYROPHOSPHATASE NUDT13, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000001060.1|UniProtKB=W5LYI8 W5LYI8 PTHR46927:SF1 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 5 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000000953.1|UniProtKB=W5LY55 W5LY55 PTHR11994:SF8 60S RIBOSOMAL PROTEIN L11-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL5 binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016528.1|UniProtKB=W5NIF7 W5NIF7 PTHR13040:SF2 AUTOPHAGY PROTEIN 5 AUTOPHAGY PROTEIN 5 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;cellular component organization#GO:0016043;piecemeal microautophagy of the nucleus#GO:0034727;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;response to stress#GO:0006950;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423 membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;autophagosome#GO:0005776;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000010375.1|UniProtKB=W5MWG3 W5MWG3 PTHR10869:SF244 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;oxidoreductase complex#GO:1990204;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000897.1|UniProtKB=W5LXY7 W5LXY7 PTHR10339:SF32 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 5-RELATED glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009608.1|UniProtKB=W5MTN3 W5MTN3 PTHR45752:SF160 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 40 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002683.1|UniProtKB=W5M466 W5M466 PTHR42861:SF6 CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000015745.1|UniProtKB=W5NFH3 W5NFH3 PTHR10574:SF419 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-3-RELATED axon guidance#GO:0007411;axon development#GO:0061564;extracellular matrix assembly#GO:0085029;tissue development#GO:0009888;multicellular organismal process#GO:0032501;cell migration#GO:0016477;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;external encapsulating structure organization#GO:0045229;system development#GO:0048731;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;substrate adhesion-dependent cell spreading#GO:0034446;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;cell adhesion#GO:0007155;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;basement membrane#GO:0005604;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000005260.1|UniProtKB=W5MD87 W5MD87 PTHR22957:SF194 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 2 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005271.1|UniProtKB=W5MD95 W5MD95 PTHR13196:SF22 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1A binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cytosol#GO:0005829;vesicle#GO:0031982;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;clathrin-coated vesicle#GO:0030136;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016916.1|UniProtKB=W5NJV3 W5NJV3 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE 5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleotide catabolic process#GO:0009166;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 LEPOC|Ensembl=ENSLOCG00000010948.1|UniProtKB=W5MYH6 W5MYH6 PTHR22811:SF3 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 11 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;Golgi organization#GO:0007030;cellular component organization#GO:0016043 vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150;vesicle coat protein#PC00235 LEPOC|Ensembl=ENSLOCG00000010472.1|UniProtKB=W5MWT2 W5MWT2 PTHR12062:SF27 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B-LIKE PRECURSOR transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi stack#GO:0005795;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004414.1|UniProtKB=W5MA65 W5MA65 PTHR23071:SF1 PHOSPHATIDYLINOSITOL GLYCAN GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3, CATALYTIC SUBUNIT catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000012700.1|UniProtKB=W5N4R9 W5N4R9 PTHR24410:SF16 HL07962P-RELATED GALECTIN-3-BINDING PROTEIN defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001109.1|UniProtKB=W5LYN9 W5LYN9 PTHR46841:SF7 OX-2 MEMBRANE GLYCOPROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839 regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;heterotypic cell-cell adhesion#GO:0034113;negative regulation of inflammatory response#GO:0050728;negative regulation of defense response#GO:0031348;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;cell body#GO:0044297;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000003972.1|UniProtKB=W5M8N9 W5M8N9 PTHR23103:SF13 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID BETA PRECURSOR LIKE PROTEIN 1 G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 neuron projection development#GO:0031175;axon development#GO:0061564;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;neuron differentiation#GO:0030182;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666 membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000013348.1|UniProtKB=W5N740 W5N740 PTHR22736:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 66 COILED-COIL DOMAIN CONTAINING 66 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000003962.1|UniProtKB=W5M8M7 W5M8M7 PTHR45703:SF48 DYNEIN HEAVY CHAIN DYNEIN AXONEMAL HEAVY CHAIN 17 microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000004513.1|UniProtKB=W5MAI9 W5MAI9 PTHR15963:SF3 GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED PROTEIN TAMALIN signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular response to stimulus#GO:0051716;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell communication#GO:0007154;regulation of biological quality#GO:0065008 membrane#GO:0016020;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;cell junction#GO:0030054;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000007946.1|UniProtKB=W5MMP1 W5MMP1 PTHR35440:SF1 TESTIS-EXPRESSED PROTEIN 36 TESTIS-EXPRESSED PROTEIN 36 LEPOC|Ensembl=ENSLOCG00000012389.1|UniProtKB=W5N3P4 W5N3P4 PTHR14076:SF9 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 2 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;coreceptor activity#GO:0015026 metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;system development#GO:0048731;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;anatomical structure development#GO:0048856;localization within membrane#GO:0051668;biological regulation#GO:0065007;tube development#GO:0035295;multicellular organismal process#GO:0032501;macromolecule localization#GO:0033036;receptor-mediated endocytosis#GO:0006898;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;circulatory system development#GO:0072359;endocytosis#GO:0006897;cellular response to hormone stimulus#GO:0032870;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;response to endogenous stimulus#GO:0009719;blood vessel morphogenesis#GO:0048514;monoatomic ion transport#GO:0006811;protein transport#GO:0015031;angiogenesis#GO:0001525;cellular localization#GO:0051641;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;response to chemical#GO:0042221;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;signal transduction#GO:0007165;cellular process#GO:0009987;receptor internalization#GO:0031623;response to hormone#GO:0009725;calcium ion transport#GO:0006816;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;import into cell#GO:0098657;protein localization to cell periphery#GO:1990778 signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008136.1|UniProtKB=W5MNB9 W5MNB9 PTHR24412:SF492 KELCH PROTEIN KELCH-LIKE PROTEIN 20 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017622.1|UniProtKB=W5NM68 W5NM68 PTHR45598:SF5 PROTEIN CBG11839-RELATED 4FE-4S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010843.1|UniProtKB=W5MY39 W5MY39 PTHR23139:SF9 RNA-BINDING PROTEIN SPLICING FACTOR U2AF 65 KDA SUBUNIT nucleic acid binding#GO:0003676;binding#GO:0005488;pre-mRNA binding#GO:0036002;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003020.1|UniProtKB=W5M596 W5M596 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008285.1|UniProtKB=W5MNV4 W5MNV4 MAP9 PTHR14739:SF9 MICROTUBULE-ASSOCIATED PROTEIN 9 MICROTUBULE-ASSOCIATED PROTEIN 9 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;mitotic spindle organization#GO:0007052;regulation of cell cycle#GO:0051726;nuclear division#GO:0000280;regulation of cytokinesis#GO:0032465;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cell division#GO:0051302;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cytokinesis#GO:1902412;mitotic spindle assembly#GO:0090307;biological regulation#GO:0065007;spindle organization#GO:0007051;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047 spindle#GO:0005819;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001689.1|UniProtKB=W5M0N5 W5M0N5 PTHR28607:SF2 EXPRESSED PROTEIN PROTEIN FAM174C extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016097.1|UniProtKB=W5NGS4 W5NGS4 PTHR15664:SF27 C20ORF30 PROTEIN TRANSMEMBRANE PROTEIN 230 establishment of organelle localization#GO:0051656;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810 secretory vesicle#GO:0099503;presynapse#GO:0098793;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 LEPOC|Ensembl=ENSLOCG00000018199.1|UniProtKB=W5NNU1 W5NNU1 PTHR14499:SF57 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD21 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006102.1|UniProtKB=W5MG67 W5MG67 PTHR24089:SF762 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SLC25A25 phosphate transmembrane transporter activity#GO:0005315;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;purine nucleotide transmembrane transporter activity#GO:0015216 establishment of localization#GO:0051234;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;localization#GO:0051179;carbohydrate derivative transport#GO:1901264;transport#GO:0006810;nitrogen compound transport#GO:0071705 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000011420.1|UniProtKB=W5N079 W5N079 PTHR46228:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006879.1|UniProtKB=W5MIW4 W5MIW4 PTHR12549:SF6 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN JUMONJI DOMAIN-CONTAINING PROTEIN 1C transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;histone demethylase activity#GO:0032452;chromatin DNA binding#GO:0031490;protein demethylase activity#GO:0140457;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;DNA binding#GO:0003677;histone modifying activity#GO:0140993 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000001114.1|UniProtKB=W5LYR5 W5LYR5 PTHR12563:SF17 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000003734.1|UniProtKB=W5M7V1 W5M7V1 PTHR11208:SF29 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000009862.1|UniProtKB=W5MUJ6 W5MUJ6 PTHR21292:SF7 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN 2 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 secretion by cell#GO:0032940;exocytosis#GO:0006887;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;exocyst#GO:0000145;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000016173.1|UniProtKB=W5NH30 W5NH30 PTHR47735:SF8 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 5 potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873 cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 transporter#PC00227;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000018021.1|UniProtKB=W5NNB3 W5NNB3 PTHR11929:SF132 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE 4 glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920;transferase activity#GO:0016740;catalytic activity#GO:0003824;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000008985.1|UniProtKB=W5MRE0 W5MRE0 PTHR10742:SF377 FLAVIN MONOAMINE OXIDASE PEROXISOMAL N(1)-ACETYL-SPERMINE_SPERMIDINE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000001647.1|UniProtKB=W5M0K8 W5M0K8 PTHR19143:SF473 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-2 protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;receptor tyrosine kinase binding#GO:0030971 animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;angiogenesis#GO:0001525;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;blood vessel morphogenesis#GO:0048514;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;tube development#GO:0035295;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 intercellular signal molecule#PC00207 Angiogenesis#P00005>Ang-2#P00246 LEPOC|Ensembl=ENSLOCG00000010747.1|UniProtKB=W5MXQ7 W5MXQ7 PTHR23240:SF26 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED 5' EXONUCLEASE APOLLO damaged DNA binding#GO:0003684;DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;5'-3' exonuclease activity#GO:0008409;hydrolase activity#GO:0016787;DNA binding#GO:0003677 response to stimulus#GO:0050896;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;telomere organization#GO:0032200;cellular response to stress#GO:0033554;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;double-strand break repair via nonhomologous end joining#GO:0006303;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974 nucleus#GO:0005634;chromosome#GO:0005694;chromosome, telomeric region#GO:0000781;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000012254.1|UniProtKB=W5N370 W5N370 PTHR12824:SF7 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GROUP XIIA SECRETORY PHOSPHOLIPASE A2 hydrolase activity#GO:0016787;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;A2-type glycerophospholipase activity#GO:0004623;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 hydrolase#PC00121;lipase#PC00143;phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000007047.1|UniProtKB=W5MJH0 W5MJH0 PTHR23194:SF7 PYGOPUS PYGOPUS HOMOLOG 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 Wnt signaling pathway#P00057>Pygo#P01464 LEPOC|Ensembl=ENSLOCG00000002934.1|UniProtKB=W5M502 W5M502 PTHR12983:SF10 RING FINGER 10 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RNF10 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 proteasomal protein catabolic process#GO:0010498;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of system process#GO:0044057;metabolic process#GO:0008152;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of nervous system development#GO:0051960;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000003882.1|UniProtKB=W5M8C5 W5M8C5 PTHR24291:SF214 CYTOCHROME P450 FAMILY 4 25-HYDROXYVITAMIN D-1 ALPHA HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014620.1|UniProtKB=W5NBI5 W5NBI5 PTHR35256:SF1 CHROMOSOME 8 OPEN READING FRAME 48 SIMILAR TO HUMAN CHROMOSOME 8 OPEN READING FRAME 48 LEPOC|Ensembl=ENSLOCG00000010924.1|UniProtKB=W5MYE0 W5MYE0 PTHR24356:SF149 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE LATS2 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 mitotic cell cycle process#GO:1903047;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;G1/S transition of mitotic cell cycle#GO:0000082;hippo signaling#GO:0035329;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;mitotic cell cycle phase transition#GO:0044772;regulation of developmental process#GO:0050793;signaling#GO:0023052;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;cell cycle#GO:0007049;regulation of programmed cell death#GO:0043067 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000010943.1|UniProtKB=W5MYG3 W5MYG3 PTHR45945:SF2 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G PROTEIN SIGNALING 14 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 cellular component organization#GO:0016043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;positive regulation of synaptic transmission#GO:0050806;nervous system process#GO:0050877;regulation of signaling#GO:0023051;regulation of trans-synaptic signaling#GO:0099177;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;cell cycle#GO:0007049;cell division#GO:0051301;microtubule cytoskeleton organization#GO:0000226;cognition#GO:0050890;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;spindle organization#GO:0007051;system process#GO:0003008;regulation of synaptic plasticity#GO:0048167;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 LEPOC|Ensembl=ENSLOCG00000015162.1|UniProtKB=W5NDF0 W5NDF0 PTHR12832:SF17 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11-LIKE PROTEIN 2 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000008745.1|UniProtKB=W5MQI7 W5MQI7 PTHR10556:SF57 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 1 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 steroid biosynthetic process#GO:0006694;regulation of biological quality#GO:0065008;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;hormone biosynthetic process#GO:0042446;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000004547.1|UniProtKB=W5MAP0 W5MAP0 PTHR12820:SF0 VACUOLAR SORTING PROTEIN 53 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004363.1|UniProtKB=W5MA06 W5MA06 PTHR10120:SF24 CAAX PRENYL PROTEASE 1 CAAX PRENYL PROTEASE 1 HOMOLOG metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000010884.1|UniProtKB=W5MY83 W5MY83 PTHR32387:SF3 WU:FJ29H11 WU:FJ29H11 LEPOC|Ensembl=ENSLOCG00000001088.1|UniProtKB=W5LYM1 W5LYM1 PTHR12911:SF22 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 2 protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane#GO:0016020;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000011356.1|UniProtKB=W5N003 W5N003 PTHR24347:SF116 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017463.1|UniProtKB=W5NLQ9 W5NLQ9 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014704.1|UniProtKB=W5NBU1 W5NBU1 PTHR31893:SF2 TRANSMEMBRANE PROTEIN 151 HOMOLOG TRANSMEMBRANE PROTEIN 151B membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009135.1|UniProtKB=W5MRY9 W5MRY9 PTHR46001:SF1 TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR TIAM1 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 signaling#GO:0023052;regulation of developmental process#GO:0050793;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;regulation of axonogenesis#GO:0050770;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cell projection organization#GO:0031344 cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 Ras Pathway#P04393>Tiam1#P04571 LEPOC|Ensembl=ENSLOCG00000010015.1|UniProtKB=W5MV38 W5MV38 PTHR11866:SF10 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of system process#GO:0044057;muscle contraction#GO:0006936;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of localization#GO:0032879;regulation of transport#GO:0051049;system process#GO:0003008;defense response#GO:0006952;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;inflammatory response#GO:0006954;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;muscle system process#GO:0003012;cellular response to stimulus#GO:0051716;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836;PI3 kinase pathway#P00048>GPCR#P01204 LEPOC|Ensembl=ENSLOCG00000012109.1|UniProtKB=W5N2N6 W5N2N6 PTHR19316:SF35 PROTEIN FOLDING REGULATOR NUCLEOTIDE EXCHANGE FACTOR SIL1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000009470.1|UniProtKB=W5MT63 W5MT63 PTHR47161:SF1 LYMPHOID-SPECIFIC HELICASE LYMPHOID-SPECIFIC HELICASE ATP-dependent activity, acting on DNA#GO:0008094;protein-macromolecule adaptor activity#GO:0030674;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 cellular response to stress#GO:0033554;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;constitutive heterochromatin formation#GO:0140719;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular process#GO:0009987;recombinational repair#GO:0000725;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;heterochromatin formation#GO:0031507;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000009344.1|UniProtKB=W5MSP0 W5MSP0 PTHR23358:SF2 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET1 dioxygenase activity#GO:0051213;catalytic activity, acting on DNA#GO:0140097;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009034.1|UniProtKB=W5MRK4 W5MRK4 PTHR12300:SF93 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 5 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013391.1|UniProtKB=W5N7A0 W5N7A0 PTHR43205:SF7 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 1-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000007649.1|UniProtKB=W5MLN8 W5MLN8 PTHR10337:SF14 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 1 receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;signaling receptor binding#GO:0005102 response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cellular response to chemical stimulus#GO:0070887;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006429.1|UniProtKB=W5MHC6 W5MHC6 PTHR16301:SF25 IMPACT-RELATED PROTEIN IMPACT intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of translational initiation#GO:0006446;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017110.1|UniProtKB=W5NKI5 W5NKI5 PTHR10896:SF8 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 2 transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000009138.1|UniProtKB=W5MRZ1 W5MRZ1 ENPP2 PTHR10151:SF21 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE AUTOTAXIN hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;catalytic activity, acting on a nucleic acid#GO:0140640;carboxylic ester hydrolase activity#GO:0052689;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;ion binding#GO:0043167;cation binding#GO:0043169;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;binding#GO:0005488;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;metal ion binding#GO:0046872 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid catabolic process#GO:0046475;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine metabolic process#GO:0046470;glycerolipid catabolic process#GO:0046503;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000013183.1|UniProtKB=W5N6I9 W5N6I9 PTHR18947:SF31 HOOK PROTEINS PROTEIN DAPLE protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;cytoskeleton organization#GO:0007010;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;cytoplasmic microtubule organization#GO:0031122;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012024.1|UniProtKB=W5N2D0 W5N2D0 PTHR14523:SF1 UNCHARACTERIZED PROTEIN C17ORF53 HOMOLOG HOMOLOGOUS RECOMBINATION OB-FOLD PROTEIN LEPOC|Ensembl=ENSLOCG00000007458.1|UniProtKB=W5MKY9 W5MKY9 PTHR14983:SF1 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 2 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 2 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;organelle assembly#GO:0070925;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;cilium organization#GO:0044782 centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869 LEPOC|Ensembl=ENSLOCG00000003166.1|UniProtKB=W5M5U6 W5M5U6 PTHR24248:SF154 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(3) DOPAMINE RECEPTOR postsynaptic neurotransmitter receptor activity#GO:0098960;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;regulation of trans-synaptic signaling#GO:0099177;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;G protein-coupled dopamine receptor signaling pathway#GO:0007212;response to nitrogen compound#GO:1901698;adrenergic receptor signaling pathway#GO:0071875;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signaling#GO:0023057;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Nicotine pharmacodynamics pathway#P06587>DRD2/ DRD3/ DRD4#P06603 LEPOC|Ensembl=ENSLOCG00000001193.1|UniProtKB=W5LZ15 W5LZ15 PTHR45845:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED KIAA1755 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000010037.1|UniProtKB=W5MV80 W5MV80 PTHR16795:SF14 LIMBIN/ELLIS-VAN CREVELD PROTEIN LIMBIN cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;ciliary membrane#GO:0060170;plasma membrane#GO:0005886;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000008800.1|UniProtKB=W5MQQ3 W5MQQ3 PTHR16557:SF12 ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED NUCLEIC ACID DIOXYGENASE ALKBH1 binding#GO:0005488;metal ion binding#GO:0046872;ferrous iron binding#GO:0008198;catalytic activity, acting on DNA#GO:0140097;iron ion binding#GO:0005506;demethylase activity#GO:0032451;catalytic activity, acting on RNA#GO:0140098;ion binding#GO:0043167;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;dioxygenase activity#GO:0051213;cation binding#GO:0043169;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000009057.1|UniProtKB=W5MRM9 W5MRM9 PTHR10264:SF135 BAND 7 PROTEIN-RELATED PODOCIN channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106 animal gross anatomical part developmental process#GO:0160108;renal system development#GO:0072001;developmental process#GO:0032502;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010367.1|UniProtKB=W5MWE4 W5MWE4 PTHR10306:SF16 SYNAPTOPHYSIN SYNAPTOPORIN exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;presynapse#GO:0098793;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008120.1|UniProtKB=W5MNA1 W5MNA1 PTHR26451:SF854 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877;system process#GO:0003008;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014603.1|UniProtKB=W5NBH0 W5NBH0 PTHR24347:SF440 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1B protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013188.1|UniProtKB=W5N6I6 W5N6I6 PTHR34035:SF1 TESTIS-EXPRESSED PROTEIN 47 TESTIS-EXPRESSED PROTEIN 47 LEPOC|Ensembl=ENSLOCG00000010146.1|UniProtKB=W5MVL2 W5MVL2 PTHR23043:SF7 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA HYPOXIA-INDUCIBLE FACTOR 1-ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;cellular response to hypoxia#GO:0071456;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;intracellular chemical homeostasis#GO:0055082;response to hypoxia#GO:0001666;regulation of gene expression#GO:0010468;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 Angiogenesis#P00005>HIF-1#P00214;Hypoxia response via HIF activation#P00030>HIF-1alpha#P00818;VEGF signaling pathway#P00056>HIF-1#P01401 LEPOC|Ensembl=ENSLOCG00000003253.1|UniProtKB=W5M632 W5M632 PTHR19441:SF103 WAP four-disulfide core domain protein PERLWAPIN ISOFORM X1 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;humoral immune response#GO:0006959;antimicrobial humoral response#GO:0019730;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;defense response to other organism#GO:0098542;response to other organism#GO:0051707 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000001276.1|UniProtKB=W5LZ94 W5LZ94 PTHR11848:SF119 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 8A-RELATED signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;heart development#GO:0007507;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000016462.1|UniProtKB=W5NI77 W5NI77 PTHR11844:SF22 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 3 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 regulation of catabolic process#GO:0009894;regulation of proteolysis#GO:0030162;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;response to chemical#GO:0042221;negative regulation of protein catabolic process#GO:0042177;response to cytokine#GO:0034097;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;response to peptide#GO:1901652;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000013959.1|UniProtKB=W5N996 W5N996 PTHR47915:SF1 SI:DKEY-19B23.7 DUF7886 DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017841.1|UniProtKB=W5NMT5 W5NMT5 PTHR24366:SF159 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS CARBOXYPEPTIDASE N SUBUNIT 2 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000016359.1|UniProtKB=W5NHU1 W5NHU1 PTHR22852:SF2 LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN DENTICLELESS PROTEIN HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;regulation of mitotic cell cycle phase transition#GO:1901990;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;protein metabolic process#GO:0019538;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000000661.1|UniProtKB=W5LXB8 W5LXB8 PTHR12607:SF3 ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY ADENOMATOUS POLYPOSIS COLI PROTEIN 2 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cell fate specification#GO:0001708;multicellular organism development#GO:0007275;regulation of protein-containing complex disassembly#GO:0043244;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;cell fate commitment#GO:0045165;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of Wnt signaling pathway#GO:0030111;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;multicellular organismal process#GO:0032501;cell migration#GO:0016477;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;regulation of microtubule-based process#GO:0032886;pattern specification process#GO:0007389;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;anatomical structure development#GO:0048856;system development#GO:0048731;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cell communication#GO:0010646 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;intracellular protein-containing complex#GO:0140535;extrinsic component of membrane#GO:0019898;membraneless organelle#GO:0043228;extrinsic component of plasma membrane#GO:0019897;polymeric cytoskeletal fiber#GO:0099513;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991 Wnt signaling pathway#P00057>APC#P01468;Angiogenesis#P00005>APC#P00195 LEPOC|Ensembl=ENSLOCG00000001865.1|UniProtKB=W5M1A2 W5M1A2 PTHR12753:SF2 AD-003 - RELATED N-TERMINAL XAA-PRO-LYS N-METHYLTRANSFERASE 2 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 methyltransferase#PC00155;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016926.1|UniProtKB=W5NJW4 W5NJW4 PTHR21442:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;developmental process#GO:0032502;spermatogenesis#GO:0007283;male gamete generation#GO:0048232;regulation of reproductive process#GO:2000241;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;cell motility#GO:0048870;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;gamete generation#GO:0007276;cell differentiation#GO:0030154;regulation of microtubule-based movement#GO:0060632;cell projection organization#GO:0030030;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000014351.1|UniProtKB=W5NAL1 W5NAL1 PTHR14107:SF15 WD REPEAT PROTEIN DYSTROPHIA MYOTONICA WD REPEAT-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134;enzyme activator activity#GO:0008047 negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of cellular process#GO:0048523;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015828.1|UniProtKB=W5NFS6 W5NFS6 PTHR12907:SF4 EGL NINE HOMOLOG-RELATED EGL NINE HOMOLOG 1 metal ion binding#GO:0046872;dioxygenase activity#GO:0051213;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;ferrous iron binding#GO:0008198;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;regulation of programmed cell death#GO:0043067;cellular response to hypoxia#GO:0071456;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;response to hypoxia#GO:0001666;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;response to stress#GO:0006950;biological regulation#GO:0065007;response to chemical#GO:0042221 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 LEPOC|Ensembl=ENSLOCG00000012632.1|UniProtKB=W5N4J3 W5N4J3 PTHR11100:SF20 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-2, MEMBRANE-BOUND ISOFORM binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;animal organ development#GO:0048513;signal transduction#GO:0007165;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 LEPOC|Ensembl=ENSLOCG00000006404.1|UniProtKB=W5MH81 W5MH81 PTHR13350:SF1 INTEGRATOR COMPLEX SUBUNIT 8 INTEGRATOR COMPLEX SUBUNIT 8 nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;integrator complex#GO:0032039;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000015780.1|UniProtKB=W5NFL9 W5NFL9 PTHR24115:SF421 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF25 cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000011602.1|UniProtKB=W5N0U7 W5N0U7 PTHR24106:SF283 NACHT, LRR AND CARD DOMAINS-CONTAINING NACHT DOMAIN-CONTAINING PROTEIN molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006507.1|UniProtKB=W5MHL5 W5MHL5 PTHR12546:SF36 FER-1-LIKE FER-1-LIKE PROTEIN 4 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;endomembrane system organization#GO:0010256;membrane organization#GO:0061024 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000014672.1|UniProtKB=W5NBQ1 W5NBQ1 PTHR47222:SF1 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 592 LEPOC|Ensembl=ENSLOCG00000005742.1|UniProtKB=W5MEX7 W5MEX7 PTHR11339:SF420 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED IGGFC-BINDING PROTEIN-RELATED structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000001052.1|UniProtKB=W5LYK6 W5LYK6 PTHR45828:SF55 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE FERRIC-CHELATE REDUCTASE 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000016579.1|UniProtKB=W5NIM2 W5NIM2 PTHR11695:SF652 ALCOHOL DEHYDROGENASE RELATED NAD(P)H OXIDOREDUCTASE RTN4IP1, MITOCHONDRIAL catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NAD(P)H dehydrogenase (quinone) activity#GO:0003955 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000001420.1|UniProtKB=W5LZR7 W5LZR7 PTHR10131:SF21 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 2 ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;tumor necrosis factor receptor superfamily binding#GO:0032813;molecular adaptor activity#GO:0060090;transferase activity#GO:0016740;catalytic activity#GO:0003824 tumor necrosis factor-mediated signaling pathway#GO:0033209;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;response to peptide#GO:1901652;regulation of intracellular signal transduction#GO:1902531;cytokine-mediated signaling pathway#GO:0019221;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of intracellular signal transduction#GO:1902533;response to cytokine#GO:0034097;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to tumor necrosis factor#GO:0034612;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 scaffold/adaptor protein#PC00226 p53 pathway#P00059>TRAF#P04620;Apoptosis signaling pathway#P00006>TRAF2#P00306 LEPOC|Ensembl=ENSLOCG00000016666.1|UniProtKB=W5NIY2 W5NIY2 PTHR22988:SF73 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE-RELATED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;embryo development#GO:0009790;intracellular signaling cassette#GO:0141124;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;signaling#GO:0023052;actomyosin structure organization#GO:0031032;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;cytoskeleton-dependent cytokinesis#GO:0061640;Rho protein signal transduction#GO:0007266;cytokinesis#GO:0000910;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;mitotic cell cycle process#GO:1903047;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;cell cycle#GO:0007049;cell division#GO:0051301;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cortical actin cytoskeleton organization#GO:0030866;anatomical structure development#GO:0048856;intracellular signal transduction#GO:0035556;cortical cytoskeleton organization#GO:0030865;regulation of cell junction assembly#GO:1901888;actin filament-based process#GO:0030029 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519 LEPOC|Ensembl=ENSLOCG00000010050.1|UniProtKB=W5MV82 W5MV82 PTHR43622:SF3 3-DEHYDROQUINATE SYNTHASE 2-EPI-5-EPI-VALIOLONE SYNTHASE ISOFORM X1 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000013893.1|UniProtKB=W5N920 W5N920 PTHR19143:SF263 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN-LIKE PROTEIN 1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of response to stimulus#GO:0048583;negative regulation of cell activation#GO:0050866;regulation of cell adhesion#GO:0030155;regulation of T cell activation#GO:0050863;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of cell adhesion#GO:0007162;regulation of multicellular organismal process#GO:0051239;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of T cell activation#GO:0050868;regulation of immune response#GO:0050776;regulation of leukocyte activation#GO:0002694;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell-cell adhesion#GO:0022407;regulation of immune system process#GO:0002682;regulation of lymphocyte activation#GO:0051249;negative regulation of leukocyte cell-cell adhesion#GO:1903038 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003106.1|UniProtKB=W5M5J8 W5M5J8 PTHR10114:SF0 60S RIBOSOMAL PROTEIN L36 LARGE RIBOSOMAL SUBUNIT PROTEIN EL36 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000012795.1|UniProtKB=W5N541 W5N541 PTHR12505:SF22 PHD FINGER TRANSCRIPTION FACTOR BAH AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000010087.1|UniProtKB=W5MVD7 W5MVD7 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle membrane contact site#GO:0044232 LEPOC|Ensembl=ENSLOCG00000015488.1|UniProtKB=W5NEK7 W5NEK7 PTHR12471:SF2 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1 intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725 membrane#GO:0016020;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proton-transporting two-sector ATPase complex#GO:0016469;ATPase complex#GO:1904949;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;proton-transporting V-type ATPase complex#GO:0033176 primary active transporter#PC00068;ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000000778.1|UniProtKB=W5LXL3 W5LXL3 PTHR18866:SF33 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000008892.1|UniProtKB=W5MR18 W5MR18 PTHR11471:SF34 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;positive regulation of signal transduction#GO:0009967;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000002545.1|UniProtKB=W5M3M8 W5M3M8 PTHR23037:SF63 CYTOKINE RECEPTOR INTERLEUKIN 2 RECEPTOR, GAMMA B ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 immune effector process#GO:0002252;cell surface receptor signaling pathway#GO:0007166;adaptive immune response#GO:0002250;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;response to peptide#GO:1901652;immunoglobulin mediated immune response#GO:0016064;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;cell communication#GO:0007154;cytokine-mediated signaling pathway#GO:0019221;immune system process#GO:0002376;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002283.1|UniProtKB=W5M2Q7 W5M2Q7 PTHR31367:SF3 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1A phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine nucleoside metabolic process#GO:0042278 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014729.1|UniProtKB=W5NBX7 W5NBX7 PTHR10933:SF9 IMMUNOGLOBULIN-BINDING PROTEIN 1 IMMUNOGLOBULIN BINDING PROTEIN 1 molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;TOR signaling#GO:0031929;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000014621.1|UniProtKB=W5NBI7 W5NBI7 PTHR24418:SF472 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE CSK non-membrane spanning protein tyrosine kinase activity#GO:0004715;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096 cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;cell junction organization#GO:0034330;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;adherens junction organization#GO:0034332;cellular component organization#GO:0016043 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 CCKR signaling map#P06959>CSK#P07072;T cell activation#P00053>Csk#P01304;Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Csk#P00913 LEPOC|Ensembl=ENSLOCG00000010047.1|UniProtKB=W5MV90 W5MV90 PTHR24046:SF2 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 3 muscle cell differentiation#GO:0042692;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;muscle cell development#GO:0055001;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;smoothened signaling pathway#GO:0007224;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;developmental process#GO:0032502;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular developmental process#GO:0048869 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000001931.1|UniProtKB=W5M1I0 W5M1I0 PTHR11576:SF15 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899;binding#GO:0005488;structural molecule activity#GO:0005198;protein binding#GO:0005515 cellular developmental process#GO:0048869;cell-cell recognition#GO:0009988;sperm-egg recognition#GO:0035036;developmental process#GO:0032502;regulation of reproductive process#GO:2000241;oogenesis#GO:0048477;biological regulation#GO:0065007;single fertilization#GO:0007338;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;anatomical structure development#GO:0048856;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609;cell recognition#GO:0008037;sexual reproduction#GO:0019953;gamete generation#GO:0007276;cell differentiation#GO:0030154;reproductive process#GO:0022414;fertilization#GO:0009566;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000010791.1|UniProtKB=W5MXW3 W5MXW3 PTHR23244:SF465 KELCH REPEAT DOMAIN ZGC:163014 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 LEPOC|Ensembl=ENSLOCG00000010933.1|UniProtKB=W5MYE9 W5MYE9 PTHR19890:SF13 FIBROBLAST GROWTH FACTOR RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR-LIKE 1 signaling receptor activity#GO:0038023;fibroblast growth factor binding#GO:0017134;kinase activity#GO:0016301;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;tyrosine protein kinase receptor#PC00233 LEPOC|Ensembl=ENSLOCG00000014771.1|UniProtKB=W5NC29 W5NC29 PTHR46030:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6 RNA_DNA DEMETHYLASE ALKBH6-RELATED oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009604.1|UniProtKB=W5MTM0 W5MTM0 PTHR23227:SF87 BUCENTAUR RELATED PROTEIN CFDP2 LEPOC|Ensembl=ENSLOCG00000000383.1|UniProtKB=W5LWB1 W5LWB1 PTHR23076:SF144 METALLOPROTEASE M41 FTSH ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1 peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824 organelle organization#GO:0006996;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000001899.1|UniProtKB=W5M1E8 W5M1E8 PTHR15706:SF6 SH3 MULTIPLE DOMAIN NEUTROPHIL CYTOSOL FACTOR 1-RELATED enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;superoxide metabolic process#GO:0006801 cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007457.1|UniProtKB=W5MKY8 W5MKY8 PTHR20437:SF3 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 13/17 BCMA TALL-1 BINDING DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008638.1|UniProtKB=W5MQ38 W5MQ38 PTHR16655:SF3 COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT PROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000004066.1|UniProtKB=W5M8Z6 W5M8Z6 PTHR22745:SF7 PROTHYMOSIN ALPHA PROTHYMOSIN ALPHA protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of apoptotic process#GO:0043066;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010101.1|UniProtKB=W5MVF5 W5MVF5 PTHR12859:SF2 PRA1 PROTEIN PRA1 FAMILY PROTEIN 3 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of localization#GO:0032879;regulation of transport#GO:0051049;biological regulation#GO:0065007;negative regulation of transport#GO:0051051 cellular anatomical structure#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000015438.1|UniProtKB=W5NEE0 W5NEE0 PTHR10845:SF196 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 17 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 negative regulation of cell communication#GO:0010648;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519 cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 LEPOC|Ensembl=ENSLOCG00000013580.1|UniProtKB=W5N7Y7 W5N7Y7 PTHR15999:SF2 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013313.1|UniProtKB=W5N700 W5N700 PTHR10877:SF145 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-1-LIKE PROTEIN 1 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to mechanical stimulus#GO:0009612;detection of stimulus#GO:0051606;detection of mechanical stimulus#GO:0050982;response to abiotic stimulus#GO:0009628 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000001811.1|UniProtKB=W5M131 W5M131 PTHR42951:SF4 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING ACYL-COENZYME A THIOESTERASE MBLAC2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017823.1|UniProtKB=W5NMR7 W5NMR7 PTHR26451:SF998 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008900.1|UniProtKB=W5MR37 W5MR37 PTHR11733:SF195 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED ENDOTHELIN-CONVERTING ENZYME-LIKE 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 LEPOC|Ensembl=ENSLOCG00000006902.1|UniProtKB=W5MIY7 W5MIY7 PTHR11961:SF56 CYTOCHROME C CYTOCHROME C electron transport chain#GO:0022900;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP synthesis#P02721>Cyt C#P02798;Apoptosis signaling pathway#P00006>Cytochrome C#P00322 LEPOC|Ensembl=ENSLOCG00000018246.1|UniProtKB=W5NNY8 W5NNY8 PTHR24240:SF15 OPSIN RHODOPSIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cellular response to radiation#GO:0071478;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;biological regulation#GO:0065007;cellular process#GO:0009987;response to radiation#GO:0009314;cellular response to light stimulus#GO:0071482;signal transduction#GO:0007165;detection of stimulus#GO:0051606 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin#P00747 LEPOC|Ensembl=ENSLOCG00000015935.1|UniProtKB=W5NG59 W5NG59 PTHR12307:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3A protein phosphatase binding#GO:0019903;carbohydrate binding#GO:0030246;protein binding#GO:0005515;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247;binding#GO:0005488 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of polysaccharide metabolic process#GO:0032881;regulation of carbohydrate biosynthetic process#GO:0043255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000007530.1|UniProtKB=W5ML77 W5ML77 PTHR16201:SF57 SEVEN TRANSMEMBRANE PROTEIN 1-RELATED LYSOSOMAL AMINO ACID TRANSPORTER 1 HOMOLOG basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;vacuolar transmembrane transport#GO:0034486;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;homeostatic process#GO:0042592;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773 LEPOC|Ensembl=ENSLOCG00000000349.1|UniProtKB=W5LW74 W5LW74 PTHR46009:SF1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG late endosome to vacuole transport#GO:0045324;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012173.1|UniProtKB=W5N2X3 W5N2X3 PTHR24027:SF323 CADHERIN-23 CADHERIN-19 beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 anatomical structure development#GO:0048856;cell adhesion#GO:0007155;cell motility#GO:0048870;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;cell-cell junction assembly#GO:0007043;cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609 anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000011123.1|UniProtKB=W5MZ57 W5MZ57 PTHR14972:SF3 AGAP011572-PA GLUCOCORTICOID-INDUCED TRANSCRIPT 1 PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007071.1|UniProtKB=W5MJK3 W5MJK3 PTHR23167:SF18 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED CYTOSPIN-A cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based process#GO:0030029 actin filament#GO:0005884;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005780.1|UniProtKB=W5MF52 W5MF52 PTHR13222:SF5 RB1-INDUCIBLE COILED-COIL RB1-INDUCIBLE COILED-COIL PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;vacuole organization#GO:0007033;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;energy derivation by oxidation of organic compounds#GO:0015980;glycogen catabolic process#GO:0005980;reticulophagy#GO:0061709;macroautophagy#GO:0016236 membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;phagophore assembly site#GO:0000407;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012619.1|UniProtKB=W5N4I0 W5N4I0 PTHR23074:SF72 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4B ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 macromolecule catabolic process#GO:0009057;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511;endosomal transport#GO:0016197;organelle organization#GO:0006996;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cellular localization#GO:0051641;localization#GO:0051179;vacuole organization#GO:0007033;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000007700.1|UniProtKB=W5MLU2 W5MLU2 PTHR19308:SF60 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN START DOMAIN-CONTAINING PROTEIN 10 LEPOC|Ensembl=ENSLOCG00000011245.1|UniProtKB=W5MZL6 W5MZL6 PTHR23115:SF191 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000015494.1|UniProtKB=W5NEL2 W5NEL2 PTHR10615:SF174 HISTONE ACETYLTRANSFERASE PHD FINGER PROTEIN 10 protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;acetyltransferase activity#GO:0016407;binding#GO:0005488;transcription regulator activity#GO:0140110;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;histone acetyltransferase activity#GO:0004402;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000017830.1|UniProtKB=W5NMS4 W5NMS4 PTHR20889:SF1 PHOSPHATASE, ORPHAN 1, 2 PYRIDOXAL PHOSPHATE PHOSPHATASE PHOSPHO2 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006891.1|UniProtKB=W5MIX3 W5MIX3 PTHR43917:SF9 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE THETA-1 catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000018045.1|UniProtKB=W5NND7 W5NND7 PTHR24232:SF95 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013568.1|UniProtKB=W5N7Y2 W5N7Y2 PTHR45975:SF2 NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF LEPOC|Ensembl=ENSLOCG00000009246.1|UniProtKB=W5MSC6 W5MSC6 PTHR23507:SF32 ZGC:174356 LYSOSOMAL PROTON-COUPLED STEROID CONJUGATE AND BILE ACID SYMPORTER SLC46A3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;vacuolar transmembrane transport#GO:0034486;establishment of localization#GO:0051234 membrane#GO:0016020;lysosomal membrane#GO:0005765;cytoplasm#GO:0005737;vacuole#GO:0005773;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000016776.1|UniProtKB=W5NJC6 W5NJC6 PTHR11711:SF484 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000016522.1|UniProtKB=W5NIE9 W5NIE9 PTHR15537:SF2 F-BOX ONLY PROTEIN 7 F-BOX ONLY PROTEIN 7 LEPOC|Ensembl=ENSLOCG00000011099.1|UniProtKB=W5MZ27 W5MZ27 PTHR25462:SF291 BONUS, ISOFORM C-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM45 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009254.1|UniProtKB=W5MSE0 W5MSE0 PTHR11792:SF15 ARRESTIN S-ARRESTIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of cell communication#GO:0010646;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;nervous system process#GO:0050877;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;localization#GO:0051179;cellular process#GO:0009987;receptor internalization#GO:0031623;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;vesicle-mediated transport#GO:0016192;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;transport#GO:0006810;negative regulation of cellular process#GO:0048523;system process#GO:0003008;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657 9+0 non-motile cilium#GO:0097731;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;photoreceptor outer segment#GO:0001750;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;photoreceptor inner segment#GO:0001917;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730 scaffold/adaptor protein#PC00226 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>beta-arrestin#P00757;Wnt signaling pathway#P00057>beta-arrestin#P01456 LEPOC|Ensembl=ENSLOCG00000015392.1|UniProtKB=W5NE82 W5NE82 PTHR34343:SF1 SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8 SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8 developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;neuron migration#GO:0001764;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;anatomical structure formation involved in morphogenesis#GO:0048646;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell migration#GO:0016477;nervous system development#GO:0007399;tube development#GO:0035295;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;cellular component organization#GO:0016043;tube morphogenesis#GO:0035239;establishment of cell polarity#GO:0030010;anatomical structure morphogenesis#GO:0009653;cell motility#GO:0048870;cell differentiation#GO:0030154 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000000739.1|UniProtKB=W5LXG6 W5LXG6 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015616.1|UniProtKB=W5NF16 W5NF16 PTHR11743:SF28 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL NON-SELECTIVE VOLTAGE-GATED ION CHANNEL VDAC3 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic anion channel activity#GO:0008308;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;mitochondrial transmembrane transport#GO:1990542;intracellular transport#GO:0046907;mitochondrial transport#GO:0006839;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000016618.1|UniProtKB=W5NIR9 W5NIR9 PTHR23333:SF16 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 2A ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 spindle localization#GO:0051653;cellular localization#GO:0051641;regulation of cellular response to stress#GO:0080135;establishment or maintenance of cell polarity#GO:0007163;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;establishment of organelle localization#GO:0051656;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of protein catabolic process#GO:0042177;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;regulation of protein metabolic process#GO:0051246;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;organelle localization#GO:0051640;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of ERAD pathway#GO:1904292;primary metabolic process#GO:0044238;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;regulation of response to endoplasmic reticulum stress#GO:1905897;establishment of cell polarity#GO:0030010;modification-dependent protein catabolic process#GO:0019941;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;mitotic cell cycle process#GO:1903047;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;establishment of spindle localization#GO:0051293;negative regulation of macromolecule metabolic process#GO:0010605 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;ATPase complex#GO:1904949;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;cytosol#GO:0005829 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000004810.1|UniProtKB=W5MBL5 W5MBL5 PTHR12313:SF13 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF185 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011350.1|UniProtKB=W5MZY5 W5MZY5 PTHR23235:SF82 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 5 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000012995.1|UniProtKB=W5N5U8 W5N5U8 PTHR11374:SF59 UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE UDP-GLUCOSE 6-DEHYDROGENASE biosynthetic process#GO:0009058;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000003364.1|UniProtKB=W5M6I3 W5M6I3 PTHR43340:SF12 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE metal ion binding#GO:0046872;magnesium ion binding#GO:0000287;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245;Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804 LEPOC|Ensembl=ENSLOCG00000013327.1|UniProtKB=W5N716 W5N716 PTHR16165:SF23 NXPE FAMILY MEMBER NEUREXOPHILIN AND PC-ESTERASE DOMAIN FAMILY, MEMBER 5 LEPOC|Ensembl=ENSLOCG00000016341.1|UniProtKB=W5NHR3 W5NHR3 PTHR47464:SF1 MACOILIN SI:DKEY-12H9.6 LEPOC|Ensembl=ENSLOCG00000017810.1|UniProtKB=W5NMQ5 W5NMQ5 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000006400.1|UniProtKB=W5MH71 W5MH71 PTHR12949:SF0 RNA POLYMERASE III DNA DIRECTED -RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000017276.1|UniProtKB=W5NL60 W5NL60 PTHR23280:SF17 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 2 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Dopamine receptor mediated signaling pathway#P05912>EPB41L2#P05952;Nicotine pharmacodynamics pathway#P06587>EPB41L2#P06598;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 LEPOC|Ensembl=ENSLOCG00000002141.1|UniProtKB=W5M282 W5M282 PTHR48023:SF7 D-XYLOSE-PROTON SYMPORTER-LIKE 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 10 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 multicellular organism development#GO:0007275;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;carbohydrate transport#GO:0008643;developmental process#GO:0032502;transport#GO:0006810;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000006817.1|UniProtKB=W5MIR6 W5MIR6 PTHR46877:SF8 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 3 ISOFORM X1 protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;system development#GO:0048731;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008296.1|UniProtKB=W5MNW6 W5MNW6 PTHR31530:SF4 MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 MINAR1 FAMILY MEMBER MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1-LIKE transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001947.1|UniProtKB=W5M1K9 W5M1K9 PTHR31131:SF2 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 2 regulation of response to stimulus#GO:0048583;negative regulation of TORC1 signaling#GO:1904262;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;response to nitrogen compound#GO:1901698;negative regulation of intracellular signal transduction#GO:1902532;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000011195.1|UniProtKB=W5MZE5 W5MZE5 PTHR11374:SF63 UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE UDP-GLUCOSE 6-DEHYDROGENASE metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007206.1|UniProtKB=W5MK09 W5MK09 PTHR10845:SF184 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G PROTEIN SIGNALING 4 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of cell communication#GO:0010648;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523 cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000012245.1|UniProtKB=W5N353 W5N353 PTHR24349:SF63 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;enzyme binding#GO:0019899;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;protein serine/threonine kinase activity#GO:0004674;mitogen-activated protein kinase binding#GO:0051019;kinase activity#GO:0016301;transferase activity#GO:0016740;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824 regulation of defense response#GO:0031347;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;inflammatory response#GO:0006954;regulation of immune response#GO:0050776;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to growth factor#GO:0070848;regulation of response to biotic stimulus#GO:0002831;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of innate immune response#GO:0045088;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to biotic stimulus#GO:0002833;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune system process#GO:0002376;response to peptide#GO:1901652;cellular response to growth factor stimulus#GO:0071363;toll-like receptor signaling pathway#GO:0002224;response to endogenous stimulus#GO:0009719;vascular endothelial growth factor receptor signaling pathway#GO:0048010;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;regulation of response to external stimulus#GO:0032101;response to chemical#GO:0042221;response to cytokine#GO:0034097 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Angiogenesis#P00005>MAPKAPK2/3#P00244;p38 MAPK pathway#P05918>MAPKAP-K2#P05920;Interleukin signaling pathway#P00036>MAPKAPK2#P00979;Ras Pathway#P04393>MAPKAP#P04564;PDGF signaling pathway#P00047>MAPKAPK2#P01157;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415 LEPOC|Ensembl=ENSLOCG00000005733.1|UniProtKB=W5MEW5 W5MEW5 PTHR46809:SF3 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN STROMAL CELL-DERIVED FACTOR 2 LEPOC|Ensembl=ENSLOCG00000001032.1|UniProtKB=W5LYF8 W5LYF8 PTHR12968:SF4 B9 DOMAIN-CONTAINING TECTONIC-LIKE COMPLEX MEMBER MKS1 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869;membrane-bounded organelle#GO:0043227 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008827.1|UniProtKB=W5MQU3 W5MQU3 PTHR22504:SF4 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000006862.1|UniProtKB=W5MIU1 W5MIU1 PTHR24012:SF812 RNA BINDING PROTEIN RNA-BINDING PROTEIN 45 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000004884.1|UniProtKB=W5MBW5 W5MBW5 PTHR22979:SF3 ZINC FINGER PROTEIN-RELATED ZINC FINGER PROTEIN 512B LEPOC|Ensembl=ENSLOCG00000008411.1|UniProtKB=W5MPB1 W5MPB1 PTHR14725:SF0 RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED LEPOC|Ensembl=ENSLOCG00000011531.1|UniProtKB=W5N0K7 W5N0K7 PTHR19290:SF94 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 sensory organ development#GO:0007423;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000007001.1|UniProtKB=W5MJB1 W5MJB1 PTHR45827:SF4 SORTING NEXIN SORTING NEXIN-18 ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 cell cycle#GO:0007049;cellular component organization#GO:0016043;cell division#GO:0051301;cell cycle process#GO:0022402;endocytosis#GO:0006897;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;cytoskeleton-dependent cytokinesis#GO:0061640;plasma membrane organization#GO:0007009;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;intracellular transport#GO:0046907;membrane invagination#GO:0010324;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;endosomal transport#GO:0016197 plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015320.1|UniProtKB=W5NDZ3 W5NDZ3 PTHR11969:SF18 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000013370.1|UniProtKB=W5N773 W5N773 PTHR15572:SF4 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 BRD4-INTERACTING CHROMATIN-REMODELING COMPLEX-ASSOCIATED PROTEIN ISOFORM X1 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603 LEPOC|Ensembl=ENSLOCG00000004762.1|UniProtKB=W5MBI0 W5MBI0 PTHR31408:SF2 HYPOTHETICAL PROTEIN LOC689986 PROTEIN SPO16 HOMOLOG nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;synaptonemal complex assembly#GO:0007130;homologous chromosome pairing at meiosis#GO:0007129;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131 membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009339.1|UniProtKB=W5MSQ2 W5MSQ2 PTHR43731:SF14 RHOMBOID PROTEASE PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000013617.1|UniProtKB=W5N835 W5N835 PTHR10887:SF365 DNA2/NAM7 HELICASE FAMILY ATP-DEPENDENT RNA HELICASE WITH ZINC FINGER DOMAIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000010805.1|UniProtKB=W5MXX9 W5MXX9 PTHR13809:SF1 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-11 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cytoplasmic side of membrane#GO:0098562;catalytic complex#GO:1902494;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 heterotrimeric G-protein#PC00117 Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;GABA-B receptor II signaling#P05731>Ggamma#P05754;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408 LEPOC|Ensembl=ENSLOCG00000015706.1|UniProtKB=W5NFC6 W5NFC6 PTHR15298:SF19 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000005428.1|UniProtKB=W5MDV7 W5MDV7 PTHR13302:SF8 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 establishment of localization in cell#GO:0051649;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;retrograde transport, vesicle recycling within Golgi#GO:0000301;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COG complex#GO:0017119 LEPOC|Ensembl=ENSLOCG00000001112.1|UniProtKB=W5LYP8 W5LYP8 PTHR24346:SF90 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SNF-RELATED SERINE_THREONINE-PROTEIN KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000007533.1|UniProtKB=W5ML81 W5ML81 PTHR15414:SF5 OS-9-RELATED PROTEIN OS-9 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular localization#GO:0051641;response to unfolded protein#GO:0006986;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;biological regulation#GO:0065007;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;protein metabolic process#GO:0019538;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;catabolic process#GO:0009056 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000001541.1|UniProtKB=W5M056 W5M056 PTHR22883:SF414 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC24-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008326.1|UniProtKB=W5MP08 W5MP08 PTHR42904:SF1 NUDIX HYDROLASE, NUDC SUBFAMILY M7GPPPN-MRNA HYDROLASE NUDT17 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;NADP+ metabolic process#GO:0006739;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;pyridine nucleotide catabolic process#GO:0019364;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000006603.1|UniProtKB=W5MHW2 W5MHW2 PTHR11954:SF22 D-DOPACHROME DECARBOXYLASE D-DOPACHROME DECARBOXYLASE catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lyase#PC00144;metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 LEPOC|Ensembl=ENSLOCG00000004137.1|UniProtKB=W5M989 W5M989 PTHR24329:SF542 HOMEOBOX PROTEIN ARISTALESS DORSAL ROOT GANGLIA HOMEOBOX PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell development#GO:0048468;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016950.1|UniProtKB=W5NJZ9 W5NJZ9 PTHR11119:SF22 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 4 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000145.1|UniProtKB=W5LVK2 W5LVK2 PTHR11062:SF117 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 2 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000014871.1|UniProtKB=W5NCF4 W5NCF4 PTHR17490:SF16 SUA5 THREONYLCARBAMOYL-AMP SYNTHASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;nucleic acid binding#GO:0003676;binding#GO:0005488;tRNA binding#GO:0000049;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000001311.1|UniProtKB=W5LZD8 W5LZD8 PTHR11292:SF7 T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN-RELATED immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013070.1|UniProtKB=W5N647 W5N647 PTHR12174:SF34 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2A hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 side of membrane#GO:0098552;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;Golgi-associated vesicle membrane#GO:0030660;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;cytoplasmic vesicle membrane#GO:0030659;vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum membrane#GO:0005789;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020 aspartic protease#PC00053;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000798.1|UniProtKB=W5LXN2 W5LXN2 PTHR22957:SF360 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 17 GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000005692.1|UniProtKB=W5MES9 W5MES9 PTHR23323:SF24 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vacuole organization#GO:0007033;endosome organization#GO:0007032;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;organelle fusion#GO:0048284 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000011560.1|UniProtKB=W5N0P0 W5N0P0 PTHR19290:SF94 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;sensory organ development#GO:0007423;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000017738.1|UniProtKB=W5NMI3 W5NMI3 PTHR45752:SF11 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8D passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;amino acid transmembrane transport#GO:0003333;carboxylic acid transmembrane transport#GO:1905039;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;carbohydrate derivative transport#GO:1901264;monoatomic anion transport#GO:0006820;establishment of localization#GO:0051234;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;biological regulation#GO:0065007;dicarboxylic acid transport#GO:0006835;monoatomic ion transmembrane transport#GO:0034220;aspartate transmembrane transport#GO:0015810;nitrogen compound transport#GO:0071705;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;signaling#GO:0023052;import across plasma membrane#GO:0098739;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;import into cell#GO:0098657;organic acid transport#GO:0015849;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;monoatomic anion transmembrane transport#GO:0098656;signal transduction#GO:0007165;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013029.1|UniProtKB=W5N5Y7 W5N5Y7 PTHR21193:SF3 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001128.1|UniProtKB=W5LYR3 W5LYR3 PTHR15491:SF16 FAMILY NOT NAMED MATRIN-TYPE DOMAIN-CONTAINING PROTEIN regulation of DNA replication#GO:0006275;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of DNA-templated DNA replication#GO:0090329;positive regulation of DNA metabolic process#GO:0051054;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA replication#GO:0045740;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of DNA-templated DNA replication initiation#GO:0030174;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000018111.1|UniProtKB=W5NNK3 W5NNK3 PTHR31046:SF2 TRANSMEMBRANE PROTEIN 121 TRANSMEMBRANE PROTEIN 121 LEPOC|Ensembl=ENSLOCG00000000469.1|UniProtKB=W5LWK4 W5LWK4 PTHR19960:SF7 TEKTIN TEKTIN organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cell motility#GO:0048870;organelle assembly#GO:0070925;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000013332.1|UniProtKB=W5N719 W5N719 PTHR34341:SF1 TRANSMEMBRANE PROTEIN 107 TRANSMEMBRANE PROTEIN 107 protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;localization#GO:0051179;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000006319.1|UniProtKB=W5MGX1 W5MGX1 PTHR15591:SF11 RUN AND SH3 DOMAIN CONTAINING AP-4 COMPLEX ACCESSORY SUBUNIT RUSC1 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000002869.1|UniProtKB=W5M4S0 W5M4S0 PTHR45949:SF1 SORTING NEXIN-4 SORTING NEXIN-30 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;reticulophagy#GO:0061709;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;vesicle-mediated transport#GO:0016192;transport#GO:0006810;autophagy of mitochondrion#GO:0000422;intracellular transport#GO:0046907;metabolic process#GO:0008152;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;mitophagy#GO:0000423;piecemeal microautophagy of the nucleus#GO:0034727;endocytic recycling#GO:0032456;catabolic process#GO:0009056;localization within membrane#GO:0051668;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179 early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006072.1|UniProtKB=W5MG22 W5MG22 PTHR12011:SF326 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G5 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015925.1|UniProtKB=W5NG55 W5NG55 PTHR15653:SF2 STRIATIN STRIATIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell communication#GO:0007154;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054;postsynapse#GO:0098794;neuron projection#GO:0043005;cell body#GO:0044297;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000009907.1|UniProtKB=W5MUP7 W5MUP7 PTHR10605:SF16 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000002887.1|UniProtKB=W5M4T7 W5M4T7 PTHR24409:SF451 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 431-LIKE transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011580.1|UniProtKB=W5N0R4 W5N0R4 PTHR11767:SF99 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 1 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000012832.1|UniProtKB=W5N586 W5N586 PTHR46603:SF1 ABSCISSION/NOCUT CHECKPOINT REGULATOR ABSCISSION_NOCUT CHECKPOINT REGULATOR phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981 negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794 cleavage furrow#GO:0032154;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;midbody#GO:0030496 LEPOC|Ensembl=ENSLOCG00000015795.1|UniProtKB=W5NFN5 W5NFN5 PTHR14776:SF1 CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1 CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000007219.1|UniProtKB=W5MK27 W5MK27 PTHR13968:SF6 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN RALY RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000338.1|UniProtKB=W5LW63 W5LW63 PTHR24241:SF20 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V2 RECEPTOR signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 regulation of anatomical structure size#GO:0090066;regulation of system process#GO:0044057;system process#GO:0003008;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;blood circulation#GO:0008015;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003235.1|UniProtKB=W5M610 W5M610 PTHR31705:SF5 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000011630.1|UniProtKB=W5N0Y2 W5N0Y2 PTHR24232:SF44 G-PROTEIN COUPLED RECEPTOR URACIL NUCLEOTIDE_CYSTEINYL LEUKOTRIENE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010905.1|UniProtKB=W5MYB5 W5MYB5 PTHR28342:SF1 MONOOXYGENASE P33MONOX-RELATED MONOOXYGENASE P33MONOX-RELATED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000001762.1|UniProtKB=W5M0Y2 W5M0Y2 PTHR43294:SF15 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-3 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;sodium ion transmembrane transporter activity#GO:0015081;primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;potassium ion homeostasis#GO:0055075;localization#GO:0051179;transmembrane transport#GO:0055085;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;export from cell#GO:0140352;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014126.1|UniProtKB=W5N9U3 W5N9U3 PTHR19282:SF216 TETRASPANIN TETRASPANIN-1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002402.1|UniProtKB=W5M356 W5M356 PTHR23004:SF10 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2B microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874 LEPOC|Ensembl=ENSLOCG00000016822.1|UniProtKB=W5NJI3 W5NJI3 PTHR32055:SF1 INTEGRIN BETA-1-BINDING PROTEIN 1 INTEGRIN BETA-1-BINDING PROTEIN 1 protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell-substrate adhesion#GO:0010810;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;negative regulation of cell adhesion#GO:0007162;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;regulation of cell-matrix adhesion#GO:0001952;regulation of cell junction assembly#GO:1901888;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;ruffle#GO:0001726;membraneless organelle#GO:0043228;cell periphery#GO:0071944;cell leading edge#GO:0031252;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000006473.1|UniProtKB=W5MHG1 W5MHG1 PTHR11941:SF178 ENOYL-COA HYDRATASE-RELATED ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL catalytic activity#GO:0003824;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 lyase#PC00144;hydratase#PC00120;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004079.1|UniProtKB=W5M953 W5M953 PTHR10684:SF2 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 2 DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134 response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000011151.1|UniProtKB=W5MZ89 W5MZ89 PTHR24067:SF311 UBIQUITIN-CONJUGATING ENZYME E2 SUMO-CONJUGATING ENZYME UBC9-B aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein sumoylation#GO:0016925;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012534.1|UniProtKB=W5N477 W5N477 PTHR19282:SF39 TETRASPANIN LEUKOCYTE SURFACE ANTIGEN CD53 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010411.1|UniProtKB=W5MWK6 W5MWK6 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000005431.1|UniProtKB=W5MDU0 W5MDU0 PTHR22917:SF3 HEMOPEXIN DOMAIN-CONTAINING PROTEIN VITRONECTIN extracellular matrix binding#GO:0050840;protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839 cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell adhesion#GO:0007155;cell adhesion mediated by integrin#GO:0033627;cell-matrix adhesion#GO:0007160 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 LEPOC|Ensembl=ENSLOCG00000003459.1|UniProtKB=W5M6V0 W5M6V0 PTHR46731:SF1 F-BOX ONLY PROTEIN 15 F-BOX ONLY PROTEIN 15 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 LEPOC|Ensembl=ENSLOCG00000009162.1|UniProtKB=W5MS21 W5MS21 PTHR23140:SF3 RNA PROCESSING PROTEIN LD23810P SR-RELATED AND CTD-ASSOCIATED FACTOR 4 nucleic acid binding#GO:0003676;binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase II complex binding#GO:0000993;RNA binding#GO:0003723;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;RNA polymerase core enzyme binding#GO:0043175 regulation of DNA-templated transcription#GO:0006355;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein-containing complex disassembly#GO:0043244;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000002277.1|UniProtKB=W5M2Q1 W5M2Q1 PTHR19378:SF7 GOLGIN- RELATED HAUS AUGMIN-LIKE COMPLEX SUBUNIT 3 chromosome segregation#GO:0007059;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;microtubule cytoskeleton#GO:0015630;HAUS complex#GO:0070652;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001331.1|UniProtKB=W5LZF2 W5LZF2 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immune system process#GO:0002376;immune effector process#GO:0002252 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000002349.1|UniProtKB=W5M313 W5M313 PTHR14432:SF6 PROSAPIP2 PROTEIN/5-AZACYTIDINE INDUCED GENE 2 5-AZACYTIDINE-INDUCED PROTEIN 2 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000008888.1|UniProtKB=W5MR08 W5MR08 PTHR12333:SF0 COMM DOMAIN CONTAINING PROTEIN 10 COMM DOMAIN-CONTAINING PROTEIN 10 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000014759.1|UniProtKB=W5NC15 W5NC15 PTHR10071:SF190 TRANSCRIPTION FACTOR GATA FAMILY MEMBER ERYTHROID TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010022.1|UniProtKB=W5MV50 W5MV50 PTHR15974:SF0 CYTOKINE-LIKE PROTEIN 1 CYTOKINE-LIKE PROTEIN 1 regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893 cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000017703.1|UniProtKB=W5NME9 W5NME9 PTHR22889:SF0 WD REPEAT-CONTAINING PROTEIN 89 WD REPEAT-CONTAINING PROTEIN 89 LEPOC|Ensembl=ENSLOCG00000008263.1|UniProtKB=W5MNT8 W5MNT8 PTHR10226:SF7 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN SPHKAP protein binding#GO:0005515;binding#GO:0005488;protein kinase A binding#GO:0051018 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008324.1|UniProtKB=W5MP03 W5MP03 PTHR10858:SF2 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE-2-BETA hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519 catabolic process#GO:0009056;programmed cell death#GO:0012501;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;execution phase of apoptosis#GO:0097194;cell death#GO:0008219;apoptotic process#GO:0006915;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000003834.1|UniProtKB=W5M891 W5M891 PTHR47615:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 LEPOC|Ensembl=ENSLOCG00000003484.1|UniProtKB=W5M6X5 W5M6X5 PTHR46625:SF1 72 KDA INOSITOL POLYPHOSPHATE 5-PHOSPHATASE PHOSPHATIDYLINOSITOL POLYPHOSPHATE 5-PHOSPHATASE TYPE IV hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010228.1|UniProtKB=W5MVW2 W5MVW2 PTHR48619:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 276 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 276 LEPOC|Ensembl=ENSLOCG00000000706.1|UniProtKB=W5LXC5 W5LXC5 PTHR11079:SF208 CYTOSINE DEAMINASE FAMILY MEMBER TRNA-SPECIFIC ADENOSINE-34 DEAMINASE CATALYTIC SUBUNIT ADAT2 tRNA-specific adenosine deaminase activity#GO:0008251;adenosine deaminase activity#GO:0004000;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;base conversion or substitution editing#GO:0016553;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;adenosine to inosine editing#GO:0006382 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCTP deaminase#P02920;Salvage pyrimidine ribonucleotides#P02775>Cytosine deaminase#P03155;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154 LEPOC|Ensembl=ENSLOCG00000020997.1|UniProtKB=Q8HQM3 Q8HQM3 PTHR42829:SF4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011486.1|UniProtKB=W5N0F7 W5N0F7 PTHR23235:SF203 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000006672.1|UniProtKB=W5MI47 W5MI47 PTHR24347:SF459 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H1 HOMOLOG-RELATED protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013026.1|UniProtKB=W5N5Y3 W5N5Y3 PTHR12122:SF4 RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED ROD CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;neuron projection#GO:0043005;cell periphery#GO:0071944;photoreceptor cell cilium#GO:0097733;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;plasma membrane#GO:0005886;ciliary membrane#GO:0060170;plasma membrane region#GO:0098590;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cell projection membrane#GO:0031253;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEgamma#P00754 LEPOC|Ensembl=ENSLOCG00000011101.1|UniProtKB=W5MZ29 W5MZ29 PTHR16453:SF9 WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER GATOR2 COMPLEX PROTEIN MIOS regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular response to amino acid starvation#GO:0034198;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;positive regulation of TORC1 signaling#GO:1904263;response to nutrient levels#GO:0031667;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004021.1|UniProtKB=W5M8U7 W5M8U7 PTHR24006:SF823 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011764.1|UniProtKB=W5N1G2 W5N1G2 PTHR24031:SF125 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX42 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000006946.1|UniProtKB=W5MJ43 W5MJ43 PTHR11211:SF41 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS HOMEOBOX 7 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;cell development#GO:0048468;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000014486.1|UniProtKB=W5NB20 W5NB20 PTHR13568:SF6 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 185B LEPOC|Ensembl=ENSLOCG00000000656.1|UniProtKB=W5LX66 W5LX66 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002831.1|UniProtKB=W5M4M4 W5M4M4 PTHR46883:SF1 BARDET-BIEDL SYNDROME 12 PROTEIN CHAPERONIN-CONTAINING T-COMPLEX MEMBER BBS12 LEPOC|Ensembl=ENSLOCG00000011665.1|UniProtKB=W5N123 W5N123 PTHR11346:SF190 GALECTIN GALECTIN carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000003782.1|UniProtKB=W5M812 W5M812 PTHR11818:SF122 BETA/GAMMA CRYSTALLIN SI:DKEY-57A22.15 structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;sensory system development#GO:0048880;system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception of light stimulus#GO:0050953;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011603.1|UniProtKB=W5N103 W5N103 PTHR24270:SF70 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 apolipoprotein#PC00052;transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000003467.1|UniProtKB=W5M6V1 W5M6V1 PTHR47977:SF16 RAS-RELATED PROTEIN RAB SI:DKEY-34D22.2 guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000006324.1|UniProtKB=W5MGY5 W5MGY5 PTHR13162:SF8 CCR4-NOT TRANSCRIPTION COMPLEX CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;CCR4-NOT complex#GO:0030014;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000008682.1|UniProtKB=W5MQ98 W5MQ98 PTHR16134:SF154 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX DOMAIN-CONTAINING PROTEIN enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000008718.1|UniProtKB=W5MQF5 W5MQF5 PTHR13128:SF12 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular localization#GO:0051641;protein transport#GO:0015031;establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011879.1|UniProtKB=W5N1U4 W5N1U4 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 ISOFORM X1 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000004235.1|UniProtKB=W5M9K7 W5M9K7 PTHR21331:SF2 BRCA1-ASSOCIATED ATM ACTIVATOR 1 INTEGRATOR COMPLEX ASSEMBLY FACTOR BRAT1 response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000015798.1|UniProtKB=W5NFP3 W5NFP3 PTHR10459:SF112 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 1 glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 LEPOC|Ensembl=ENSLOCG00000017108.1|UniProtKB=W5NKI4 W5NKI4 PTHR45632:SF45 LD33804P KELCH-LIKE PROTEIN 32 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009366.1|UniProtKB=W5MSR3 W5MSR3 PTHR28032:SF1 FI02826P FI02826P binding#GO:0005488;protein-containing complex binding#GO:0044877 primary metabolic process#GO:0044238;response to misfolded protein#GO:0051788;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;response to topologically incorrect protein#GO:0035966;cellular response to topologically incorrect protein#GO:0035967;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;localization#GO:0051179;response to stress#GO:0006950;macromolecule localization#GO:0033036;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;cellular response to misfolded protein#GO:0071218;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 LEPOC|Ensembl=ENSLOCG00000016225.1|UniProtKB=W5NH96 W5NH96 PTHR43720:SF4 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;cellular process#GO:0009987;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;oxoacid metabolic process#GO:0043436;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000010667.1|UniProtKB=W5MXG0 W5MXG0 PTHR10177:SF57 CYCLINS CYCLIN-I2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000010396.1|UniProtKB=W5MWI9 W5MWI9 PTHR45897:SF2 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH AFFINITY CHOLINE TRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 establishment of localization#GO:0051234;neuromuscular synaptic transmission#GO:0007274;metabolic process#GO:0008152;transport#GO:0006810;synaptic transmission, cholinergic#GO:0007271;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell body#GO:0044297;perikaryon#GO:0043204;cell junction#GO:0030054;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072 LEPOC|Ensembl=ENSLOCG00000006972.1|UniProtKB=W5MJ78 W5MJ78 PTHR24411:SF3 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000011335.1|UniProtKB=W5MZX8 W5MZX8 PTHR10037:SF209 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1I sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;sodium channel activity#GO:0005272;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;regulation of cellular process#GO:0050794;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;calcium ion import#GO:0070509;establishment of localization#GO:0051234;system process#GO:0003008;transport#GO:0006810;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;positive regulation of cytosolic calcium ion concentration#GO:0007204;positive regulation of secretion#GO:0051047;nervous system process#GO:0050877;calcium ion transmembrane transport#GO:0070588;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;action potential#GO:0001508;regulation of membrane potential#GO:0042391;calcium ion transmembrane import into cytosol#GO:0097553;regulation of transport#GO:0051049;transmission of nerve impulse#GO:0019226;regulation of localization#GO:0032879;calcium ion transport#GO:0006816;monoatomic cation transmembrane transport#GO:0098655;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 sodium channel complex#GO:0034706;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;neuron projection#GO:0043005;membrane#GO:0016020;membrane protein complex#GO:0098796 voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000008210.1|UniProtKB=W5MNL0 W5MNL0 PTHR13068:SF194 CGI-12 PROTEIN-RELATED TRANSCRIPTION TERMINATION FACTOR 3, MITOCHONDRIAL regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;organelle assembly#GO:0070925;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;mitochondrial ribosome assembly#GO:0061668;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component assembly#GO:0022607;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011064.1|UniProtKB=W5MYY6 W5MYY6 PTHR45739:SF7 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1 epithelial structure maintenance#GO:0010669;homeostatic process#GO:0042592;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;cellular process#GO:0009987;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;cell-substrate adhesion#GO:0031589;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000006976.1|UniProtKB=W5MJ83 W5MJ83 PTHR12775:SF0 PROTEIN C20ORF43 HOMOLOG REPLICATION TERMINATION FACTOR 2 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000015819.1|UniProtKB=W5NFR8 W5NFR8 PTHR15146:SF0 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137B regulation of hemopoiesis#GO:1903706;positive regulation of TOR signaling#GO:0032008;regulation of tissue remodeling#GO:0034103;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;negative regulation of multicellular organismal process#GO:0051241;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of cell differentiation#GO:0045595;positive regulation of response to stimulus#GO:0048584;negative regulation of immune system process#GO:0002683;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of bone remodeling#GO:0046850;regulation of metabolic process#GO:0019222;positive regulation of TORC1 signaling#GO:1904263;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;positive regulation of signaling#GO:0023056;regulation of myeloid cell differentiation#GO:0045637;regulation of intracellular signal transduction#GO:1902531;regulation of bone resorption#GO:0045124;regulation of signaling#GO:0023051;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006 membrane#GO:0016020;lysosomal membrane#GO:0005765;cytoplasm#GO:0005737;vacuole#GO:0005773;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010728.1|UniProtKB=W5MXN1 W5MXN1 PTHR12416:SF2 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN FCF1 HOMOLOG ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000008201.1|UniProtKB=W5MNJ8 W5MNJ8 PTHR46110:SF2 HOMEOBOX PROTEIN HMX HOMEOBOX PROTEIN HMX3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009990.1|UniProtKB=W5MV08 W5MV08 PTHR47410:SF1 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 8 molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023 regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;toll-like receptor signaling pathway#GO:0002224;defense response to virus#GO:0051607;immune response-regulating signaling pathway#GO:0002764;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;canonical NF-kappaB signal transduction#GO:0007249;positive regulation of response to stimulus#GO:0048584;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;regulation of gene expression#GO:0010468;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of gene expression#GO:0010628;response to external stimulus#GO:0009605;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to biotic stimulus#GO:0002831;response to external biotic stimulus#GO:0043207;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;response to virus#GO:0009615;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;intracellular signal transduction#GO:0035556;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000006383.1|UniProtKB=W5MH57 W5MH57 PTHR48012:SF9 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 25 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008998.1|UniProtKB=W5MRG2 W5MRG2 PTHR12389:SF0 ZINC FINGER PROTEIN 294 E3 UBIQUITIN-PROTEIN LIGASE LISTERIN transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ribosomal large subunit binding#GO:0043023;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;ribosome binding#GO:0043022;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;rescue of stalled cytosolic ribosome#GO:0072344;modification-dependent protein catabolic process#GO:0019941;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;modification-dependent macromolecule catabolic process#GO:0043632;translation#GO:0006412;protein catabolic process#GO:0030163;gene expression#GO:0010467;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;translational elongation#GO:0006414 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012766.1|UniProtKB=W5N4Z8 W5N4Z8 PTHR23407:SF1 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000004592.1|UniProtKB=W5MAU1 W5MAU1 PTHR24064:SF196 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 31-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000013587.1|UniProtKB=W5N7Z4 W5N7Z4 PTHR10663:SF372 GUANYL-NUCLEOTIDE EXCHANGE FACTOR F-BOX ONLY PROTEIN 8 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000004673.1|UniProtKB=W5MB34 W5MB34 PTHR10129:SF51 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFB DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000011224.1|UniProtKB=W5MZI2 W5MZI2 PTHR11977:SF78 VILLIN SCINDERIN cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;actin binding#GO:0003779;actin filament binding#GO:0051015;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515 negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;multicellular organismal process#GO:0032501;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;anatomical structure development#GO:0048856;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;supramolecular fiber organization#GO:0097435;system development#GO:0048731;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament depolymerization#GO:0030834;regulation of anatomical structure size#GO:0090066;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;nervous system development#GO:0007399;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;central nervous system development#GO:0007417;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 FAS signaling pathway#P00020>Gelsolin#P00611 LEPOC|Ensembl=ENSLOCG00000009038.1|UniProtKB=W5MRK2 W5MRK2 PTHR47027:SF25 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009147.1|UniProtKB=W5MS07 W5MS07 PTHR19302:SF14 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 3 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cellular process#GO:0009987;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;reproductive process#GO:0022414;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000005269.1|UniProtKB=W5MD88 W5MD88 PTHR24229:SF18 NEUROPEPTIDES RECEPTOR NEUROPEPTIDES B_W RECEPTOR TYPE 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016586.1|UniProtKB=W5NIM6 W5NIM6 PTHR28665:SF1 BEN DOMAIN-CONTAINING PROTEIN 3 BEN DOMAIN-CONTAINING PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488;rDNA binding#GO:0000182;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;nucleolus organization#GO:0007000;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000011721.1|UniProtKB=W5N195 W5N195 PTHR16209:SF4 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN BINDING PROTEIN 1-LIKE G protein-coupled receptor signaling pathway#GO:0007186;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to chemokine#GO:1990869;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemokine#GO:1990868;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097 LEPOC|Ensembl=ENSLOCG00000007107.1|UniProtKB=W5MJP7 W5MJP7 PTHR12299:SF29 HYALURONIC ACID-BINDING PROTEIN 4 SERPINE1 MRNA-BINDING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006682.1|UniProtKB=W5MI61 W5MI61 PTHR12550:SF18 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR-RELATED PROTEIN 2 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;histone H3K9me2/3 reader activity#GO:0062072;protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000006160.1|UniProtKB=W5MGE7 W5MGE7 PTHR11206:SF268 MULTIDRUG RESISTANCE PROTEIN MULTIDRUG AND TOXIN EXTRUSION PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014614.1|UniProtKB=W5NBH4 W5NBH4 PTHR24366:SF53 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN CONTAINING 1 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000016912.1|UniProtKB=W5NJV0 W5NJV0 PTHR12199:SF3 INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN 1 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000011107.1|UniProtKB=W5MZ46 W5MZ46 PTHR21812:SF1 INO80 COMPLEX SUBUNIT E INO80 COMPLEX SUBUNIT E regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA replication#GO:0006275;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Ino80 complex#GO:0031011 LEPOC|Ensembl=ENSLOCG00000005275.1|UniProtKB=W5MD99 W5MD99 PTHR11937:SF570 ACTIN ACTIN, EPSILON 1 structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cadherin signaling pathway#P00012>F-actin#P00470;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 LEPOC|Ensembl=ENSLOCG00000004941.1|UniProtKB=W5MC36 W5MC36 PTHR13073:SF0 BLOC-1 COMPLEX SUBUNIT 1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 1 transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 intracellular protein-containing complex#GO:0140535;BLOC-1 complex#GO:0031083;protein-containing complex#GO:0032991 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015801.1|UniProtKB=W5NFP4 W5NFP4 PTHR12106:SF46 SORTILIN RELATED SORTILIN ISOFORM X1 endocytosis#GO:0006897;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;Golgi to endosome transport#GO:0006895;cellular localization#GO:0051641;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport#GO:0016192;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017239.1|UniProtKB=W5NL13 W5NL13 PTHR13334:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN US10M cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000003896.1|UniProtKB=W5M8E4 W5M8E4 PTHR10543:SF110 BETA-CAROTENE DIOXYGENASE BETA,BETA-CAROTENE 15,15'-DIOXYGENASE ISOFORM X1 dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 diterpenoid metabolic process#GO:0016101;isoprenoid metabolic process#GO:0006720;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;terpenoid metabolic process#GO:0006721;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;catabolic process#GO:0009056;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014247.1|UniProtKB=W5NA82 W5NA82 PTHR15283:SF3 GREMLIN 1 GREMLIN-1 receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine binding#GO:0019955;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011469.1|UniProtKB=W5N0D4 W5N0D4 PTHR24139:SF34 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 85_88 KDA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 A2-type glycerophospholipase activity#GO:0004623;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;deacylase activity#GO:0160215;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity#GO:0016787;thiolester hydrolase activity#GO:0016790;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289 regulation of lipid metabolic process#GO:0019216;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;regulation of cellular component biogenesis#GO:0044087;regulation of macromolecule metabolic process#GO:0060255;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;glycerophospholipid metabolic process#GO:0006650;regulation of lipid biosynthetic process#GO:0046890 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 phospholipase#PC00186;lipase#PC00143 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738 LEPOC|Ensembl=ENSLOCG00000001241.1|UniProtKB=W5LZ60 W5LZ60 PTHR23167:SF87 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED MICAL-LIKE PROTEIN 2 actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013891.1|UniProtKB=W5N918 W5N918 PTHR15333:SF2 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 LEPOC|Ensembl=ENSLOCG00000007347.1|UniProtKB=W5MKL2 W5MKL2 PTHR15012:SF8 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM2 actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840 actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;apical junction complex#GO:0043296;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;cell junction#GO:0030054;membraneless organelle#GO:0043228;adherens junction#GO:0005912 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000015357.1|UniProtKB=W5NE40 W5NE40 PTHR43326:SF8 METHIONYL-TRNA SYNTHETASE METHIONINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000007521.1|UniProtKB=W5ML80 W5ML80 PTHR11001:SF2 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 mitochondrial fission#GO:0000266;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015412.1|UniProtKB=W5NEA6 W5NEA6 PTHR11515:SF30 GLYCOPROTEIN HORMONE BETA CHAIN FOLLITROPIN SUBUNIT BETA ISOFORM X1-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;reproductive structure development#GO:0048608;reproductive process#GO:0022414;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108;cell communication#GO:0007154;anatomical structure development#GO:0048856;female gonad development#GO:0008585;system development#GO:0048731;reproductive system development#GO:0061458;signal transduction#GO:0007165;cellular process#GO:0009987;sex differentiation#GO:0007548;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;gonad development#GO:0008406;developmental process#GO:0032502;development of primary sexual characteristics#GO:0045137;multicellular organism development#GO:0007275;animal organ development#GO:0048513 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000011743.1|UniProtKB=W5N1E1 W5N1E1 PTHR11533:SF276 PROTEASE M1 ZINC METALLOPROTEASE GLUTAMYL AMINOPEPTIDASE catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 protein processing#GO:0016485;peptide hormone processing#GO:0016486;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;peptide catabolic process#GO:0043171;regulation of systemic arterial blood pressure#GO:0003073;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;multicellular organismal process#GO:0032501;protein maturation#GO:0051604;blood circulation#GO:0008015;hormone metabolic process#GO:0042445;metabolic process#GO:0008152;system process#GO:0003008;macromolecule metabolic process#GO:0043170;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;catabolic process#GO:0009056;circulatory system process#GO:0003013;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000011432.1|UniProtKB=W5N089 W5N089 PTHR31443:SF2 FAMILY NOT NAMED ZGC:153675 LEPOC|Ensembl=ENSLOCG00000000876.1|UniProtKB=W5LXX2 W5LXX2 PTHR11669:SF20 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 4 catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 replication fork#GO:0005657;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 LEPOC|Ensembl=ENSLOCG00000013735.1|UniProtKB=W5N8I7 W5N8I7 PTHR43903:SF3 NEUROLIGIN NEUROLIGIN-2 membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;organelle#GO:0043226;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;synaptic membrane#GO:0097060;cell junction#GO:0030054 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009108.1|UniProtKB=W5MRU5 W5MRU5 PTHR22776:SF42 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PROTEIN MAL2 biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane microdomain#GO:0098857;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane raft#GO:0045121;intracellular vesicle#GO:0097708;vesicle#GO:0031982 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003386.1|UniProtKB=W5M6K2 W5M6K2 PTHR46404:SF1 DNA POLYMERASE IOTA DNA POLYMERASE IOTA transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887 DNA synthesis involved in DNA replication#GO:0090592;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;translesion synthesis#GO:0019985;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004225.1|UniProtKB=W5M9J3 W5M9J3 PTHR11567:SF213 ACID PHOSPHATASE-RELATED 2-PHOSPHOXYLOSE PHOSPHATASE 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000003278.1|UniProtKB=W5M660 W5M660 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000013107.1|UniProtKB=W5N686 W5N686 PTHR21522:SF35 PROTON CHANNEL OTOP PROTON CHANNEL OTOP2 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016299.1|UniProtKB=W5NHK6 W5NHK6 PTHR11003:SF11 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 12 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008196.1|UniProtKB=W5MNJ2 W5MNJ2 PTHR10165:SF15 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 2 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cell communication#GO:0007154;dephosphorylation#GO:0016311;cellular response to stimulus#GO:0051716;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014197.1|UniProtKB=W5NA30 W5NA30 PTHR12387:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;proteasome regulatory particle, lid subcomplex#GO:0008541;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;proteasome complex#GO:0000502 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000014033.1|UniProtKB=W5N9J1 W5N9J1 PTHR10625:SF23 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 11 deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096;histone modifying activity#GO:0140993;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007 protein-containing complex#GO:0032991;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000006350.1|UniProtKB=W5MH08 W5MH08 PTHR24416:SF341 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TIE-1 signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transmembrane signaling receptor activity#GO:0004888 positive regulation of angiogenesis#GO:0045766;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of developmental process#GO:0050793;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of angiogenesis#GO:0045765;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of vasculature development#GO:1901342;positive regulation of developmental process#GO:0051094;cell surface receptor signaling pathway#GO:0007166;regulation of anatomical structure morphogenesis#GO:0022603 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014244.1|UniProtKB=W5NA78 W5NA78 PTHR13377:SF3 PLACENTAL PROTEIN 6 TRANSMEMBRANE PROTEIN 115 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;organelle#GO:0043226;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004343.1|UniProtKB=W5M9X9 W5M9X9 PTHR11311:SF16 SPONDIN SPONDIN-1 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000013549.1|UniProtKB=W5N7V1 W5N7V1 PTHR11353:SF94 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT EPSILON protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein folding chaperone complex#GO:0101031;chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000005161.1|UniProtKB=W5MCV7 W5MCV7 PTHR10985:SF5 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-3 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000000720.1|UniProtKB=W5LXE3 W5LXE3 PTHR45781:SF5 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 2 DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000014789.1|UniProtKB=W5NC57 W5NC57 PTHR12112:SF12 BNIP - RELATED BCL2_ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 2 programmed cell death#GO:0012501;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004180.1|UniProtKB=W5M9F3 W5M9F3 PTHR22940:SF4 TIMEOUT/TIMELESS-2 PROTEIN TIMELESS HOMOLOG DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular response to stress#GO:0033554;regulation of DNA replication#GO:0006275;DNA-templated DNA replication#GO:0006261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;regulation of cell cycle#GO:0051726;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;regulation of DNA-templated DNA replication#GO:0090329;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of DNA-templated DNA replication#GO:2000104;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;regulation of metabolic process#GO:0019222;DNA integrity checkpoint signaling#GO:0031570;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;chromosome#GO:0005694;replication fork#GO:0005657;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000014539.1|UniProtKB=W5NB85 W5NB85 PTHR10071:SF149 TRANSCRIPTION FACTOR GATA FAMILY MEMBER ENDOTHELIAL TRANSCRIPTION FACTOR GATA-2 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;positive regulation of angiogenesis#GO:0045766;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell fate commitment#GO:0045165;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of vasculature development#GO:1901342;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of angiogenesis#GO:0045765;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>GATA2/4#P06859 LEPOC|Ensembl=ENSLOCG00000010201.1|UniProtKB=W5MVT8 W5MVT8 PTHR22727:SF13 PROTEIN CBG13728 ENDOSOME_LYSOSOME-ASSOCIATED APOPTOSIS AND AUTOPHAGY REGULATOR 1 macroautophagy#GO:0016236;biological regulation#GO:0065007;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;organelle assembly#GO:0070925 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endosome#GO:0005768;intracellular organelle#GO:0043229;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;vacuole#GO:0005773;plasma membrane#GO:0005886;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;lytic vacuole#GO:0000323;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000002505.1|UniProtKB=W5M3J3 W5M3J3 PTHR11417:SF3 SOMATOTROPIN,PROLACTIN SOMATOLACTIN ALPHA-RELATED hormone receptor binding#GO:0051427;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;protein binding#GO:0005515;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;response to peptide hormone#GO:0043434;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;developmental process#GO:0032502;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to hormone#GO:0009725;animal organ development#GO:0048513;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000010402.1|UniProtKB=W5MWJ5 W5MWJ5 PTHR23192:SF33 OLFACTOMEDIN-RELATED MYOCILIN osteoblast differentiation#GO:0001649;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;ossification#GO:0001503;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000003595.1|UniProtKB=W5M7A0 W5M7A0 PTHR13857:SF42 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3A-LIKE RNA binding#GO:0003723;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824 RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;base conversion or substitution editing#GO:0016553;metabolic process#GO:0008152;RNA modification#GO:0009451;nucleobase-containing compound metabolic process#GO:0006139;cytidine to uridine editing#GO:0016554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000015108.1|UniProtKB=W5ND86 W5ND86 PTHR24205:SF14 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 1 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000013719.1|UniProtKB=W5N8G7 W5N8G7 PTHR11699:SF120 ALDEHYDE DEHYDROGENASE-RELATED CYTOSOLIC 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 tetrahydrofolate metabolic process#GO:0046653;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000009166.1|UniProtKB=W5MS46 W5MS46 PTHR22826:SF115 RHO GUANINE EXCHANGE FACTOR-RELATED GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003001.1|UniProtKB=W5M583 W5M583 PTHR10807:SF64 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR4 phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;protein phosphatase binding#GO:0019903;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein binding#GO:0005515;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902 dephosphorylation#GO:0016311;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000005283.1|UniProtKB=W5MDC3 W5MDC3 PTHR23162:SF7 OUTER DENSE FIBER OF SPERM TAILS 2 PROTEIN BCAP regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;regulation of cilium assembly#GO:1902017;negative regulation of cellular process#GO:0048523;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cellular component biogenesis#GO:0044087;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000008976.1|UniProtKB=W5MRC5 W5MRC5 PTHR10668:SF103 PHYTOENE DEHYDROGENASE PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000006275.1|UniProtKB=W5MGS3 W5MGS3 PTHR10201:SF7 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-23 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000003636.1|UniProtKB=W5M7F6 W5M7F6 PTHR45810:SF12 HISTONE H3.2 HISTONE H3 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003448.1|UniProtKB=W5M6T1 W5M6T1 PTHR34491:SF156 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED AUGMIN COMPLEX SUBUNIT DGT5 LEPOC|Ensembl=ENSLOCG00000004565.1|UniProtKB=W5MAR1 W5MAR1 PTHR11530:SF15 D-AMINO ACID OXIDASE D-AMINO-ACID OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000001036.1|UniProtKB=W5LYH1 W5LYH1 PTHR11590:SF80 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000007798.1|UniProtKB=W5MM61 W5MM61 PTHR24136:SF14 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 11 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;positive regulation of metabolic process#GO:0009893;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule metabolic process#GO:0010604;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000016268.1|UniProtKB=W5NHF7 W5NHF7 PTHR48182:SF2 PROTEIN SERAC1 PROTEIN SERAC1 LEPOC|Ensembl=ENSLOCG00000014006.1|UniProtKB=W5N9G8 W5N9G8 PTHR24351:SF115 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-5 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;TORC1 signaling#GO:0038202;regulation of DNA-templated transcription#GO:0006355;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;TOR signaling#GO:0031929;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 protein modifying enzyme#PC00260 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;p38 MAPK pathway#P05918>MSK1#P06040;PDGF signaling pathway#P00047>p90RSK#P01142 LEPOC|Ensembl=ENSLOCG00000014862.1|UniProtKB=W5NCE2 W5NCE2 PTHR11848:SF246 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 16 receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;heart morphogenesis#GO:0003007;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000004422.1|UniProtKB=W5MA73 W5MA73 PTHR24264:SF7 TRYPSIN-RELATED TRYPSIN-2-LIKE PRECURSOR-RELATED catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000008243.1|UniProtKB=W5MNR1 W5MNR1 PTHR22870:SF398 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC2 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000015176.1|UniProtKB=W5NDG4 W5NDG4 PTHR22806:SF0 NUCLEOPORIN NUP37 P37 -RELATED NUCLEOPORIN NUP37 nuclear pore outer ring#GO:0031080;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002097.1|UniProtKB=W5M264 W5M264 PTHR13265:SF2 THO COMPLEX SUBUNIT 1 THO COMPLEX SUBUNIT 1 cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transcription export complex#GO:0000346;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013189.1|UniProtKB=W5N6J1 W5N6J1 SHC4 PTHR10337:SF12 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell surface receptor signaling pathway#GO:0007166 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011925.1|UniProtKB=W5N1Z8 W5N1Z8 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 ISOFORM X1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017128.1|UniProtKB=W5NKK8 W5NKK8 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED reverse transcriptase#PC00200;viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000013899.1|UniProtKB=W5N926 W5N926 PTHR46169:SF17 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000009190.1|UniProtKB=W5MS56 W5MS56 PTHR13500:SF0 NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1 NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000004619.1|UniProtKB=W5MAY1 W5MAY1 PTHR23316:SF11 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-8 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;nucleocytoplasmic transport#GO:0006913;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;protein localization to organelle#GO:0033365 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001589.1|UniProtKB=W5M0B7 W5M0B7 PTHR10978:SF5 SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091 respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 dehydrogenase#PC00092 TCA cycle#P00051>Succinate Dehydrogenase#P01273 LEPOC|Ensembl=ENSLOCG00000011114.1|UniProtKB=W5MZ48 W5MZ48 PTHR46025:SF1 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE 2 catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;UDP-xylosyltransferase activity#GO:0035252;catalytic activity#GO:0003824;transferase activity#GO:0016740;xylosyltransferase activity#GO:0042285;pentosyltransferase activity#GO:0016763 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011178.1|UniProtKB=W5MZF1 W5MZF1 PTHR24115:SF893 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF21B ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal motor activity#GO:0003774;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000002922.1|UniProtKB=W5M4X5 W5M4X5 PTHR15902:SF2 NEURITIN-RELATED NEURITIN-LIKE PROTEIN neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;developmental growth#GO:0048589;cell growth#GO:0016049;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;developmental cell growth#GO:0048588;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000001962.1|UniProtKB=W5M1L1 W5M1L1 PTHR31253:SF0 BRI3-BINDING PROTEIN BRI3-BINDING PROTEIN mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000003401.1|UniProtKB=W5M6M2 W5M6M2 PTHR10605:SF45 HEPARAN SULFATE SULFOTRANSFERASE N-HEPARAN SULFATE SULFOTRANSFERASE 4 deacylase activity#GO:0160215;transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;deacetylase activity#GO:0019213 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000008736.1|UniProtKB=W5MQH2 W5MQH2 PTHR22802:SF475 C-TYPE LECTIN SUPERFAMILY MEMBER CD302 ANTIGEN binding#GO:0005488;signaling receptor activity#GO:0038023;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006417.1|UniProtKB=W5MH99 W5MH99 PTHR10570:SF9 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;cellular process#GO:0009987;lymphocyte activation#GO:0046649;multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;biological regulation#GO:0065007;T cell differentiation#GO:0030217;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cellular developmental process#GO:0048869;leukocyte activation#GO:0045321;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;mononuclear cell differentiation#GO:1903131;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell development#GO:0048468;immune system process#GO:0002376;lymphocyte differentiation#GO:0030098;cell activation#GO:0001775;cell communication#GO:0007154;anatomical structure development#GO:0048856 side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD3 eta#P01302 LEPOC|Ensembl=ENSLOCG00000010917.1|UniProtKB=W5MYD0 W5MYD0 PTHR16154:SF22 NEURABIN NEURABIN-1 molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein-membrane adaptor activity#GO:0043495 supramolecular fiber organization#GO:0097435;system development#GO:0048731;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;actin filament organization#GO:0007015;calcium-mediated signaling#GO:0019722;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;filopodium#GO:0030175;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cortical cytoskeleton#GO:0030863;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;cell cortex#GO:0005938;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000014590.1|UniProtKB=W5NBF5 W5NBF5 PTHR11616:SF96 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1 amino acid transmembrane transporter activity#GO:0015171;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283 amino acid transport#GO:0006865;transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 LEPOC|Ensembl=ENSLOCG00000014663.1|UniProtKB=W5NBP4 W5NBP4 PTHR10590:SF22 SODIUM/NUCLEOSIDE COTRANSPORTER SODIUM_NUCLEOSIDE COTRANSPORTER 1 ISOFORM X1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;nucleoside transmembrane transporter activity#GO:0005337;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;carbohydrate derivative transmembrane transporter activity#GO:1901505;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;nucleobase-containing compound transmembrane transporter activity#GO:0015932 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleobase-containing compound transport#GO:0015931 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016045.1|UniProtKB=W5NGK5 W5NGK5 PTHR22760:SF1 GLYCOSYLTRANSFERASE DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000012811.1|UniProtKB=W5N554 W5N554 PTHR11824:SF17 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-1 voltage-gated ion channel#PC00241 Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 LEPOC|Ensembl=ENSLOCG00000001919.1|UniProtKB=W5M1H5 W5M1H5 PTHR10383:SF51 SERINE INCORPORATOR SERINE INCORPORATOR 3 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000011243.1|UniProtKB=W5MZK6 W5MZK6 PTHR11783:SF43 SULFOTRANSFERASE SULT AMINE SULFOTRANSFERASE-RELATED sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013463.1|UniProtKB=W5N7J3 W5N7J3 PTHR28625:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;positive regulation of cell projection organization#GO:0031346;positive regulation of cellular component organization#GO:0051130;regulation of microtubule-based process#GO:0032886;regulation of cell projection assembly#GO:0060491;positive regulation of organelle organization#GO:0010638;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of organelle assembly#GO:1902115;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035 microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000013952.1|UniProtKB=W5N9A2 W5N9A2 PTHR23220:SF21 INTEGRIN ALPHA INTEGRIN ALPHA-11 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell surface receptor signaling pathway#GO:0007166;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609 integrin complex#GO:0008305;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000008079.1|UniProtKB=W5MN65 W5MN65 PTHR11134:SF31 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-1 COMPLEX SUBUNIT BETA-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;membrane coat#GO:0030117;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;intracellular organelle#GO:0043229;coated membrane#GO:0048475;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle coat#GO:0030120 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000005225.1|UniProtKB=W5MD33 W5MD33 PTHR16483:SF0 GASTROKINE 1 BRICHOS DOMAIN-CONTAINING PROTEIN 5 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000003258.1|UniProtKB=W5M639 W5M639 PTHR13674:SF2 GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN PROTEIN FAM162A response to stress#GO:0006950;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hypoxia#GO:0001666;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;cellular response to hypoxia#GO:0071456;programmed cell death#GO:0012501;response to abiotic stimulus#GO:0009628;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;cell death#GO:0008219;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;apoptotic process#GO:0006915;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;cellular response to chemical stimulus#GO:0070887;regulation of release of cytochrome c from mitochondria#GO:0090199;positive regulation of cellular component organization#GO:0051130;cellular response to stress#GO:0033554;neuron apoptotic process#GO:0051402;positive regulation of organelle organization#GO:0010638 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000002437.1|UniProtKB=W5M399 W5M399 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to stimulus#GO:0050896;response to chemical#GO:0042221;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000737.1|UniProtKB=W5LXG1 W5LXG1 PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;pyruvate metabolic process#GO:0006090;small molecule catabolic process#GO:0044282 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000001081.1|UniProtKB=W5LYL1 W5LYL1 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009502.1|UniProtKB=W5MTA5 W5MTA5 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016592.1|UniProtKB=W5NIN5 W5NIN5 PTHR13037:SF16 FORMIN FORMIN-2 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;actin filament bundle assembly#GO:0051017 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000001434.1|UniProtKB=W5LZT3 W5LZT3 PTHR21148:SF11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015206.1|UniProtKB=W5NDK4 W5NDK4 PTHR48092:SF14 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 1, GROUP H, MEMBER 4 sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000005353.1|UniProtKB=W5MDK9 W5MDK9 PTHR11849:SF156 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-1 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 LEPOC|Ensembl=ENSLOCG00000001178.1|UniProtKB=W5LYW7 W5LYW7 PTHR34488:SF1 SI:CH211-245H14.1-RELATED SI:CH211-245H14.1-RELATED LEPOC|Ensembl=ENSLOCG00000006170.1|UniProtKB=W5MGE3 W5MGE3 PTHR24410:SF20 HL07962P-RELATED BTB DOMAIN CONTAINING 2 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005242.1|UniProtKB=W5MD56 W5MD56 PTHR14002:SF21 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1-RELATED cellular anatomical structure#GO:0110165;cell surface#GO:0009986;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006952.1|UniProtKB=W5MJ51 W5MJ51 PTHR24343:SF539 SERINE/THREONINE KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000018041.1|UniProtKB=W5NND3 W5NND3 PTHR35660:SF1 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000016783.1|UniProtKB=W5NJE1 W5NJE1 PTHR13677:SF2 LD41638P PROTEIN DENND6B molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 recycling endosome#GO:0055037;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000000239.1|UniProtKB=W5LVV8 W5LVV8 PTHR14453:SF107 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN POLY [ADP-RIBOSE] POLYMERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transcription regulator activity#GO:0140110;pentosyltransferase activity#GO:0016763 negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of gene expression#GO:0010629;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biological process#GO:0048519;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000006984.1|UniProtKB=W5MJ90 W5MJ90 PTHR24286:SF100 CYTOCHROME P450 26 CYTOCHROME P450 26C1 catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;central nervous system development#GO:0007417;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;regulation of hormone levels#GO:0010817;isoprenoid metabolic process#GO:0006720;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;terpenoid metabolic process#GO:0006721;multicellular organismal process#GO:0032501;monocarboxylic acid catabolic process#GO:0072329;hormone metabolic process#GO:0042445;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;multicellular organism development#GO:0007275;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;developmental process#GO:0032502 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000015746.1|UniProtKB=W5NFI2 W5NFI2 PTHR10398:SF2 AFADIN AFADIN cytoskeletal adaptor activity#GO:0008093;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;adherens junction organization#GO:0034332;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cell adhesion#GO:0007155;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cell-cell junction maintenance#GO:0045217 plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;adherens junction#GO:0005912;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 Alzheimer disease-presenilin pathway#P00004>Afadin#P00146 LEPOC|Ensembl=ENSLOCG00000002607.1|UniProtKB=W5M3Y2 W5M3Y2 PTHR11269:SF13 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 3 transcription factor binding#GO:0008134;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of macromolecule metabolic process#GO:0060255;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;response to radiation#GO:0009314;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;photoperiodism#GO:0009648;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;response to abiotic stimulus#GO:0009628;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;rhythmic process#GO:0048511;negative regulation of DNA-templated transcription#GO:0045892;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217 Circadian clock system#P00015>per#G01499;Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>Per#P00504 LEPOC|Ensembl=ENSLOCG00000013385.1|UniProtKB=W5N790 W5N790 PTHR11560:SF15 39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL10M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000000623.1|UniProtKB=W5LX32 W5LX32 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000008507.1|UniProtKB=W5MPP1 W5MPP1 PTHR10293:SF16 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 reductase#PC00198;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014612.1|UniProtKB=W5NBJ7 W5NBJ7 PTHR22625:SF32 PLEXIN PLEXIN-A3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of nervous system development#GO:0051960;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;cellular developmental process#GO:0048869;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of cell adhesion#GO:0007162;axon development#GO:0061564;positive regulation of axonogenesis#GO:0050772;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;signaling#GO:0023052;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of multicellular organismal development#GO:2000026;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;regulation of axonogenesis#GO:0050770;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;anatomical structure development#GO:0048856;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;axon guidance#GO:0007411;regulation of biological quality#GO:0065008;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;synapse assembly#GO:0007416;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;neuron differentiation#GO:0030182;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011202.1|UniProtKB=W5MZG0 W5MZG0 PTHR12098:SF5 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 2 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015386.1|UniProtKB=W5NE78 W5NE78 PTHR15715:SF17 CENTROSOMAL PROTEIN OF 170 KDA CENTROSOMAL PROTEIN OF 170 KDA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 microtubule cytoskeleton organization#GO:0000226;microtubule anchoring#GO:0034453;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002118.1|UniProtKB=W5M273 W5M273 PTHR47958:SF31 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036 membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000017633.1|UniProtKB=W5NM79 W5NM79 PTHR24343:SF166 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 6 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 sexual reproduction#GO:0019953;spermatid development#GO:0007286;spermatid differentiation#GO:0048515;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;reproductive process#GO:0022414;cell differentiation#GO:0030154;gamete generation#GO:0007276;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;cellular process#GO:0009987;male gamete generation#GO:0048232 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006093.1|UniProtKB=W5MG53 W5MG53 PTHR34347:SF1 DNA REPAIR-SCAFFOLDING PROTEIN SPIDR DNA REPAIR-SCAFFOLDING PROTEIN response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of localization#GO:0032879;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001600.1|UniProtKB=W5M0D5 W5M0D5 AHSG PTHR13814:SF6 FETUIN ALPHA-2-HS-GLYCOPROTEIN molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;acute inflammatory response#GO:0002526;inflammatory response#GO:0006954;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;regulation of bone mineralization#GO:0030500;regulation of multicellular organismal process#GO:0051239;response to stress#GO:0006950;defense response#GO:0006952;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000013753.1|UniProtKB=W5N8K9 W5N8K9 PTHR10527:SF1 IMPORTIN BETA IMPORTIN SUBUNIT BETA-1 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004325.1|UniProtKB=W5M9V9 W5M9V9 PTHR10024:SF180 SYNAPTOTAGMIN SYNAPTOTAGMIN-9 lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543 regulation of localization#GO:0032879;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;synaptic signaling#GO:0099536;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;positive regulation of organelle organization#GO:0010638;cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;positive regulation of cellular component organization#GO:0051130;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;chemical synaptic transmission#GO:0007268 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;secretory vesicle#GO:0099503;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000000589.1|UniProtKB=W5LWZ5 W5LWZ5 PTHR10603:SF6 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN RNA-BINDING PROTEIN FXR1 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA stability#GO:0043487;positive regulation of translation#GO:0045727;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;nucleic acid transport#GO:0050657;regulation of neurogenesis#GO:0050767;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;modulation of chemical synaptic transmission#GO:0050804;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;positive regulation of neurogenesis#GO:0050769;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA localization#GO:0006403;RNA transport#GO:0050658;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;transport#GO:0006810;regulation of synaptic plasticity#GO:0048167;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of neuronal synaptic plasticity#GO:0048168;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;regulation of translation#GO:0006417;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;positive regulation of nervous system development#GO:0051962;positive regulation of cell differentiation#GO:0045597;animal organ development#GO:0048513;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;positive regulation of macromolecule metabolic process#GO:0010604;regulation of trans-synaptic signaling#GO:0099177 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;neuron projection#GO:0043005;nucleus#GO:0005634;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 translation factor#PC00223;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000006100.1|UniProtKB=W5MG61 W5MG61 PTHR10201:SF25 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-15 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141 LEPOC|Ensembl=ENSLOCG00000004943.1|UniProtKB=W5MC37 W5MC37 PTHR15256:SF6 INTEGRAL MEMBRANE PROTEIN DGCR2/IDD INTEGRAL MEMBRANE PROTEIN DGCR2_IDD cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000005041.1|UniProtKB=W5MCH4 W5MCH4 PTHR43831:SF1 ISOBUTYRYL-COA DEHYDROGENASE ISOBUTYRYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000001121.1|UniProtKB=W5LYQ4 W5LYQ4 PTHR46841:SF7 OX-2 MEMBRANE GLYCOPROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488 negative regulation of response to stimulus#GO:0048585;regulation of response to external stimulus#GO:0032101;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;heterotypic cell-cell adhesion#GO:0034113;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell adhesion#GO:0007155;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347 cell body#GO:0044297;neuron projection#GO:0043005;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424 LEPOC|Ensembl=ENSLOCG00000003017.1|UniProtKB=W5M5B7 W5M5B7 PTHR10896:SF21 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000010135.1|UniProtKB=W5MVJ3 W5MVJ3 PTHR23430:SF20 HISTONE H2A CORE HISTONE MACRO-H2A.1 structural molecule activity#GO:0005198 regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of transcription by RNA polymerase I#GO:0006356;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000002147.1|UniProtKB=W5M290 W5M290 PTHR24103:SF700 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM7 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010197.1|UniProtKB=W5MVS9 W5MVS9 PTHR45684:SF20 RE74312P SMALL COPII COAT GTPASE SAR1B hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;membrane organization#GO:0061024;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;coated membrane#GO:0048475;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle coat#GO:0030120;cytoplasm#GO:0005737;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000016280.1|UniProtKB=W5NHH5 W5NHH5 FSHR PTHR24372:SF5 GLYCOPROTEIN HORMONE RECEPTOR FOLLICLE-STIMULATING HORMONE RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;cell communication#GO:0007154;reproductive system development#GO:0061458;multicellular organismal reproductive process#GO:0048609;female gonad development#GO:0008585;system development#GO:0048731;multicellular organismal process#GO:0032501;gonad development#GO:0008406;biological regulation#GO:0065007;development of primary male sexual characteristics#GO:0046546;male sex differentiation#GO:0046661;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental process#GO:0032502;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;reproductive structure development#GO:0048608;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;hormone-mediated signaling pathway#GO:0009755;animal gross anatomical part developmental process#GO:0160108;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;rhythmic process#GO:0048511;response to chemical#GO:0042221;response to hormone#GO:0009725;cellular process#GO:0009987;sex differentiation#GO:0007548;male gonad development#GO:0008584;signal transduction#GO:0007165;animal organ development#GO:0048513;multicellular organism development#GO:0007275;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;development of primary sexual characteristics#GO:0045137 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016451.1|UniProtKB=W5NI61 W5NI61 PTHR12945:SF0 TRANSLATION INITIATION FACTOR EIF3-RELATED TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000014711.1|UniProtKB=W5NBV6 W5NBV6 PTHR43153:SF1 ELECTRON TRANSFER FLAVOPROTEIN ALPHA ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363 oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009897.1|UniProtKB=W5MUQ1 W5MUQ1 PTHR13817:SF88 TITIN CONTACTIN 3B structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000005433.1|UniProtKB=W5MDU8 W5MDU8 PTHR10572:SF24 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;isoprenoid metabolic process#GO:0006720;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;peroxisomal membrane#GO:0005778;endomembrane system#GO:0012505;microbody#GO:0042579;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 reductase#PC00198 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA reductase#P00491 LEPOC|Ensembl=ENSLOCG00000012432.1|UniProtKB=W5N3U4 W5N3U4 PTHR11588:SF540 TUBULIN TUBULIN GAMMA CHAIN purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 spindle organization#GO:0007051;chromosome organization#GO:0051276;microtubule polymerization#GO:0046785;mitotic cell cycle process#GO:1903047;microtubule polymerization or depolymerization#GO:0031109;mitotic sister chromatid segregation#GO:0000070;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;nuclear division#GO:0000280;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;sister chromatid segregation#GO:0000819;microtubule nucleation#GO:0007020;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;mitotic spindle organization#GO:0007052 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 tubulin#PC00228;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000002849.1|UniProtKB=W5M4P9 W5M4P9 PTHR16146:SF46 INTELECTIN INTELECTIN-1A-RELATED LEPOC|Ensembl=ENSLOCG00000010418.1|UniProtKB=W5MWL5 W5MWL5 PTHR14286:SF2 GENE, 49355-RELATED CENTROSOMAL PROTEIN 15 LEPOC|Ensembl=ENSLOCG00000018020.1|UniProtKB=W5NNB2 W5NNB2 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 14A ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000006208.1|UniProtKB=W5MGK9 W5MGK9 PTHR46075:SF4 CHIMERIN FAMILY MEMBER BETA-CHIMAERIN enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 male gamete generation#GO:0048232;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;vesicle organization#GO:0016050;cellular anatomical entity morphogenesis#GO:0032989;spermatogenesis#GO:0007283;developmental process#GO:0032502;gamete generation#GO:0007276;cell differentiation#GO:0030154;reproductive process#GO:0022414;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process involved in reproduction#GO:0003006;cellular component organization#GO:0016043;germ cell development#GO:0007281;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;cellular component assembly involved in morphogenesis#GO:0010927;spermatid differentiation#GO:0048515;organelle assembly#GO:0070925;spermatid development#GO:0007286;acrosome assembly#GO:0001675;sexual reproduction#GO:0019953 LEPOC|Ensembl=ENSLOCG00000006178.1|UniProtKB=W5MGG4 W5MGG4 PTHR10527:SF110 IMPORTIN BETA TRANSPORTIN-2 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;protein localization to organelle#GO:0033365 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001598.1|UniProtKB=W5M0D0 W5M0D0 PTHR15225:SF4 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN N-MYC-INTERACTOR cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000006467.1|UniProtKB=W5MHH5 W5MHH5 PTHR13408:SF1 DNA-DIRECTED RNA POLYMERASE III ZGC:171971 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000378.1|UniProtKB=W5LWA7 W5LWA7 PTHR11949:SF2 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 7 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 Toll receptor signaling pathway#P00054>IRF3#P01374 LEPOC|Ensembl=ENSLOCG00000006347.1|UniProtKB=W5MH02 W5MH02 PTHR12113:SF11 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 1 protein binding#GO:0005515;signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545 regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009665.1|UniProtKB=W5MTV8 W5MTV8 PTHR24020:SF18 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN skeletal muscle tissue development#GO:0007519;cellular process#GO:0009987;tissue development#GO:0009888;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;muscle organ development#GO:0007517;striated muscle cell differentiation#GO:0051146;cellular developmental process#GO:0048869;animal organ development#GO:0048513;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;muscle tissue development#GO:0060537;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000006289.1|UniProtKB=W5MGT8 W5MGT8 PTHR10972:SF215 OXYSTEROL-BINDING PROTEIN-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 3-LIKE PROTEIN binding#GO:0005488;sterol binding#GO:0032934;lipid binding#GO:0008289;steroid binding#GO:0005496 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000008516.1|UniProtKB=W5MPQ2 W5MPQ2 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to other organism#GO:0051707 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000001579.1|UniProtKB=W5M0A7 W5M0A7 PTHR10334:SF521 CYSTEINE-RICH SECRETORY PROTEIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 18 MEMBER A-RELATED polysaccharide binding#GO:0030247;binding#GO:0005488;carbohydrate binding#GO:0030246 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017442.1|UniProtKB=W5NLN8 W5NLN8 PTHR23411:SF41 TAPASIN IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000002034.1|UniProtKB=W5M1U8 W5M1U8 PTHR16002:SF5 TRANSMEMBRANE PROTEIN 248-LIKE TRANSMEMBRANE PROTEIN 248 LEPOC|Ensembl=ENSLOCG00000016719.1|UniProtKB=W5NJ48 W5NJ48 PTHR28664:SF3 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi apparatus subcompartment#GO:0098791;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000015934.1|UniProtKB=W5NG58 W5NG58 BMT2 PTHR21008:SF0 S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1-RELATED S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1 molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;response to nitrogen compound#GO:1901698;response to nutrient levels#GO:0031667;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432 LEPOC|Ensembl=ENSLOCG00000014702.1|UniProtKB=W5NBU7 W5NBU7 PTHR11089:SF33 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3-LIKE PROTEIN nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000015883.1|UniProtKB=W5NG01 W5NG01 PTHR24304:SF2 CYTOCHROME P450 FAMILY 7 24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008846.1|UniProtKB=W5MQX0 W5MQX0 PTHR11365:SF2 5-OXOPROLINASE RELATED 5-OXOPROLINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000000333.1|UniProtKB=W5LW57 W5LW57 PTHR11036:SF145 SEMAPHORIN SEMAPHORIN-4A ISOFORM X1-RELATED protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;chemotaxis#GO:0006935;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;response to chemical#GO:0042221;taxis#GO:0042330;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000006774.1|UniProtKB=W5MIH4 W5MIH4 PTHR11324:SF16 IL16-RELATED PDZ DOMAIN-CONTAINING PROTEIN 2 cytokine#PC00083;interleukin superfamily#PC00128 LEPOC|Ensembl=ENSLOCG00000007741.1|UniProtKB=W5MLY7 W5MLY7 PTHR23248:SF58 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303 transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;biological regulation#GO:0065007;phospholipid transport#GO:0015914;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;lipid localization#GO:0010876;plasma membrane organization#GO:0007009;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011147.1|UniProtKB=W5MZ84 W5MZ84 PTHR10041:SF9 COLIPASE COLIPASE enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015653.1|UniProtKB=W5NF59 W5NF59 PTHR14304:SF12 CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN CELL CYCLE AND APOPTOSIS REGULATOR PROTEIN 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004123.1|UniProtKB=W5M976 W5M976 PTHR43270:SF11 BETA-ALA-HIS DIPEPTIDASE CYTOSOLIC NON-SPECIFIC DIPEPTIDASE peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;catalytic activity#GO:0003824 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000010052.1|UniProtKB=W5MV86 W5MV86 PTHR14614:SF1 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN METHYLTRANSFERASE-LIKE PROTEIN 21E methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005214.1|UniProtKB=W5MD13 W5MD13 PTHR45684:SF6 RE74312P SMALL COPII COAT GTPASE SAR1A ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003 vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;coated membrane#GO:0048475;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000013510.1|UniProtKB=W5N7Q1 W5N7Q1 PTHR31931:SF2 PROTEIN CHURCHILL PROTEIN CHURCHILL cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;fibroblast growth factor receptor signaling pathway#GO:0008543;biological regulation#GO:0065007;response to fibroblast growth factor#GO:0071774;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363 LEPOC|Ensembl=ENSLOCG00000016957.1|UniProtKB=W5NK04 W5NK04 PTHR24189:SF69 MYOTROPHIN MYOTROPHIN regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of protein depolymerization#GO:1901879;cellular component organization or biogenesis#GO:0071840;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003063.1|UniProtKB=W5M5F7 W5M5F7 PTHR21664:SF1 CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66 NUDC DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000008598.1|UniProtKB=W5MPZ7 W5MPZ7 PTHR24055:SF79 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 15 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 PDGF signaling pathway#P00047>ERK#P01143;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Interleukin signaling pathway#P00036>ERK#P00965;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Parkinson disease#P00049>ERK#P01211;EGF receptor signaling pathway#P00018>ERK1-2#P00543 LEPOC|Ensembl=ENSLOCG00000012505.1|UniProtKB=W5N449 W5N449 PTHR24270:SF16 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED VERY LOW-DENSITY LIPOPROTEIN RECEPTOR protein binding#GO:0005515;binding#GO:0005488 multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;multicellular organism development#GO:0007275;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810;developmental process#GO:0032502;endocytosis#GO:0006897;central nervous system development#GO:0007417;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transfer/carrier protein#PC00219;apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000017673.1|UniProtKB=W5NMB9 W5NMB9 PTHR45822:SF4 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 1 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888 positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of establishment of protein localization#GO:0070201;response to fatty acid#GO:0070542;positive regulation of hormone secretion#GO:0046887;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of protein transport#GO:0051223;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of hormone secretion#GO:0046883;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of protein localization#GO:0032880;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;response to oxygen-containing compound#GO:1901700;response to lipid#GO:0033993;response to chemical#GO:0042221;regulation of insulin secretion#GO:0050796;cellular process#GO:0009987;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of protein secretion#GO:0050714;regulation of localization#GO:0032879;regulation of transport#GO:0051049 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000001130.1|UniProtKB=W5LYR7 W5LYR7 PTHR18460:SF3 TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER TELO2-INTERACTING PROTEIN 1 HOMOLOG intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016845.1|UniProtKB=W5NJL3 W5NJL3 PTHR12656:SF11 BRG-1 ASSOCIATED FACTOR 250 BAF250 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1B protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;binding#GO:0005488;chromatin binding#GO:0003682 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000010094.1|UniProtKB=W5MVE8 W5MVE8 PTHR31395:SF5 SHISA PROTEIN SHISA-4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015369.1|UniProtKB=W5NE55 W5NE55 PTHR19282:SF199 TETRASPANIN TETRASPANIN-15 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011894.1|UniProtKB=W5N1X5 W5N1X5 PTHR24347:SF451 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000007108.1|UniProtKB=W5MJP9 W5MJP9 PTHR13409:SF0 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L51 LARGE RIBOSOMAL SUBUNIT PROTEIN ML51 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000000084.1|UniProtKB=W5LVD8 W5LVD8 PTHR13593:SF154 FAMILY NOT NAMED SI:DKEY-266F7.9 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 LEPOC|Ensembl=ENSLOCG00000008272.1|UniProtKB=W5MNU0 W5MNU0 PTHR23101:SF103 RAB GDP/GTP EXCHANGE FACTOR RAB5 GDP_GTP EXCHANGE FACTOR-LIKE enzyme binding#GO:0019899;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular vesicle#GO:0097708;vesicle#GO:0031982 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000001906.1|UniProtKB=W5M1E5 W5M1E5 PTHR11071:SF593 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003093.1|UniProtKB=W5M5J6 W5M5J6 PTHR22715:SF0 TRANSFORMING GROWTH FACTOR BETA REGULATED GENE 1 TRANSFORMING GROWTH FACTOR BETA REGULATOR 1 biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 intercellular signal molecule#PC00207;growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000005598.1|UniProtKB=W5MEF6 W5MEF6 PTHR10288:SF97 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;RNA binding#GO:0003723 positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005840.1|UniProtKB=W5MF90 W5MF90 PTHR46880:SF11 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN PR_SET DOMAIN 11 LEPOC|Ensembl=ENSLOCG00000007855.1|UniProtKB=W5MMC8 W5MMC8 PTHR11200:SF127 INOSITOL 5-PHOSPHATASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 5-PHOSPHATASE A catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of microtubule polymerization or depolymerization#GO:0031110;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of microtubule polymerization#GO:0031113;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein polymerization#GO:0032272;regulation of microtubule-based process#GO:0032886;regulation of cellular component biogenesis#GO:0044087;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;negative regulation of cellular component organization#GO:0051129;regulation of protein-containing complex assembly#GO:0043254;negative regulation of organelle organization#GO:0010639 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;ruffle#GO:0001726;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000001655.1|UniProtKB=W5M0K2 W5M0K2 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009494.1|UniProtKB=W5MT96 W5MT96 PTHR45916:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;condensed chromosome#GO:0000793;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000009264.1|UniProtKB=W5MSD8 W5MSD8 PTHR21415:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;snRNA binding#GO:0017069 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA processing factor#PC00147;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000454.1|UniProtKB=W5LWJ2 W5LWJ2 PTHR21431:SF0 PREFOLDIN SUBUNIT 6 PREFOLDIN SUBUNIT 6 protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001945.1|UniProtKB=W5M1J2 W5M1J2 PTHR13817:SF153 TITIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 22 structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;supramolecular fiber organization#GO:0097435;animal gross anatomical part developmental process#GO:0160108;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;developmental process#GO:0032502;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987 supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;A band#GO:0031672;contractile muscle fiber#GO:0043292;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;M band#GO:0031430;intracellular organelle#GO:0043229 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011530.1|UniProtKB=W5N0K8 W5N0K8 PTHR21637:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD20 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017898.1|UniProtKB=W5NMZ2 W5NMZ2 PTHR22923:SF87 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 4 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cytokine-mediated signaling pathway#GO:0001959;regulation of response to cytokine stimulus#GO:0060759;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of cytokine-mediated signaling pathway#GO:0001961;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014156.1|UniProtKB=W5N9X8 W5N9X8 PTHR10383:SF5 SERINE INCORPORATOR SERINE INCORPORATOR 4 cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014465.1|UniProtKB=W5NAZ5 W5NAZ5 PTHR24031:SF221 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A-I translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181 intracellular protein-containing complex#GO:0140535;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017501.1|UniProtKB=W5NLU7 W5NLU7 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016314.1|UniProtKB=W5NHM9 W5NHM9 PTHR11647:SF58 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 5 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;primary metabolic process#GO:0044238;pyrimidine nucleobase catabolic process#GO:0006208;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;metabolic process#GO:0008152;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRAM#P00330;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 LEPOC|Ensembl=ENSLOCG00000017184.1|UniProtKB=W5NKT0 W5NKT0 PTHR47130:SF3 SI:DKEY-19B23.11-RELATED ZONA PELLUCIDA PROTEIN LEPOC|Ensembl=ENSLOCG00000011212.1|UniProtKB=W5MZG4 W5MZG4 PTHR21245:SF4 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN DEAD END PROTEIN HOMOLOG 1 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000016062.1|UniProtKB=W5NGN1 W5NGN1 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183-LIKE-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012647.1|UniProtKB=W5N4L4 W5N4L4 PTHR23302:SF66 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 7 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;channel activity#GO:0015267 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000013253.1|UniProtKB=W5N6R8 W5N6R8 PTHR15907:SF107 DUF614 FAMILY PROTEIN-RELATED PLAC8 ONZIN-RELATED PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000016044.1|UniProtKB=W5NGL7 W5NGL7 PTHR10574:SF274 NETRIN/LAMININ-RELATED USHERIN anatomical structure development#GO:0048856;tissue development#GO:0009888;developmental process#GO:0032502 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000014814.1|UniProtKB=W5NC82 W5NC82 PTHR32193:SF5 REGULATOR OF CELL CYCLE RGCC RGCC PROTEIN LEPOC|Ensembl=ENSLOCG00000008327.1|UniProtKB=W5MP13 W5MP13 PTHR14699:SF1 STI2 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 21B microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;intraciliary transport#GO:0042073;protein localization to cilium#GO:0061512;intraciliary retrograde transport#GO:0035721;protein localization to organelle#GO:0033365;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043 intraciliary transport particle A#GO:0030991;protein-containing complex#GO:0032991;intraciliary transport particle#GO:0030990 LEPOC|Ensembl=ENSLOCG00000015840.1|UniProtKB=W5NFU2 W5NFU2 SCARA5 PTHR19331:SF488 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CLASS A MEMBER 5 cargo receptor activity#GO:0038024 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000016440.1|UniProtKB=W5NI46 W5NI46 PTHR10578:SF151 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 1 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987;biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013865.1|UniProtKB=W5N8Z3 W5N8Z3 PTHR11406:SF0 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphoglycerate kinase activity#GO:0004618;catalytic activity#GO:0003824;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;ATP binding#GO:0005524;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate biosynthetic process#GO:0016051;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;monocarboxylic acid metabolic process#GO:0032787;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;pyruvate metabolic process#GO:0006090;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;energy derivation by oxidation of organic compounds#GO:0015980;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;purine nucleotide catabolic process#GO:0006195;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 LEPOC|Ensembl=ENSLOCG00000002725.1|UniProtKB=W5M497 W5M497 PTHR31954:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;sexual reproduction#GO:0019953;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cilium movement involved in cell motility#GO:0060294;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;cilium organization#GO:0044782;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;gamete generation#GO:0007276;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;cilium assembly#GO:0060271;cellular component organization#GO:0016043;sperm motility#GO:0097722 cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000006850.1|UniProtKB=W5MIS1 W5MIS1 PTHR23235:SF54 KRUEPPEL-LIKE TRANSCRIPTION FACTOR E3 SUMO-PROTEIN LIGASE EGR2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000017458.1|UniProtKB=W5NLQ4 W5NLQ4 PTHR26451:SF885 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488 response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008955.1|UniProtKB=W5MR99 W5MR99 PTHR21549:SF0 MUTATED IN BLADDER CANCER 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 112 LEPOC|Ensembl=ENSLOCG00000006642.1|UniProtKB=W5MI16 W5MI16 PTHR12308:SF37 ANOCTAMIN ANOCTAMIN-9 transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 biological regulation#GO:0065007;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;lipid localization#GO:0010876 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000006138.1|UniProtKB=W5MGB1 W5MGB1 PTHR45618:SF1 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED DICARBOXYLATE CARRIER SLC25A8 proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324 cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;adaptive thermogenesis#GO:1990845;homeostatic process#GO:0042592;response to cold#GO:0009409;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;multicellular organismal-level homeostasis#GO:0048871;establishment of localization#GO:0051234;transport#GO:0006810;temperature homeostasis#GO:0001659;intracellular transport#GO:0046907;response to temperature stimulus#GO:0009266;multicellular organismal process#GO:0032501;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;response to stress#GO:0006950 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014582.1|UniProtKB=W5NBD4 W5NBD4 PTHR24241:SF127 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 22 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001360.1|UniProtKB=W5LZJ2 W5LZJ2 PTHR46012:SF3 IP22168P GLUCOSIDE XYLOSYLTRANSFERASE 1 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000010775.1|UniProtKB=W5MXU1 W5MXU1 PTHR38490:SF1 CYSTEINE AND TYROSINE-RICH PROTEIN 1 CYSTEINE AND TYROSINE-RICH PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000001654.1|UniProtKB=W5M0M1 W5M0M1 PTHR24170:SF2 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 early endosome to late endosome transport#GO:0045022;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;neurogenesis#GO:0022008;vesicle-mediated transport to the plasma membrane#GO:0098876;localization within membrane#GO:0051668;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731;neuron projection development#GO:0031175;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;endosomal transport#GO:0016197;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;endocytic recycling#GO:0032456;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular localization#GO:0051641;neuron development#GO:0048666 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;plasma membrane#GO:0005886;late endosome#GO:0005770;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000006088.1|UniProtKB=W5MG51 W5MG51 PTHR21254:SF1 C2 DOMAIN-CONTAINING PROTEIN 3 C2 DOMAIN-CONTAINING PROTEIN 3 cilium organization#GO:0044782;localization#GO:0051179;protein localization to microtubule organizing center#GO:1905508;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;protein localization to centrosome#GO:0071539;cell cycle#GO:0007049;cellular component organization#GO:0016043;cilium assembly#GO:0060271;membraneless organelle assembly#GO:0140694;protein localization to cytoskeleton#GO:0044380;microtubule organizing center organization#GO:0031023;intracellular protein localization#GO:0008104;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;protein localization to microtubule cytoskeleton#GO:0072698;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriolar satellite#GO:0034451;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000000637.1|UniProtKB=W5LX48 W5LX48 PTHR11471:SF31 TUMOR NECROSIS FACTOR FAMILY MEMBER LYMPHOTOXIN-ALPHA receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of canonical NF-kappaB signal transduction#GO:0043122;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;positive regulation of apoptotic process#GO:0043065;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870;Apoptosis signaling pathway#P00006>TNF#P00259 LEPOC|Ensembl=ENSLOCG00000016562.1|UniProtKB=W5NIJ6 W5NIJ6 PTHR16770:SF3 PROTEIN RIPPLY-LIKE PROTEIN RIPPLY2 negative regulation of macromolecule biosynthetic process#GO:0010558;embryonic pattern specification#GO:0009880;embryo development#GO:0009790;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pattern specification process#GO:0007389;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015986.1|UniProtKB=W5NGC4 W5NGC4 PTHR15032:SF38 N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;cell body#GO:0044297;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000003724.1|UniProtKB=W5M7T5 W5M7T5 PTHR23503:SF99 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 3 sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657;carbohydrate transport#GO:0008643;transport#GO:0006810;import across plasma membrane#GO:0098739;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000012848.1|UniProtKB=W5N5A8 W5N5A8 PTHR23302:SF35 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 3 passive transmembrane transporter activity#GO:0022803;gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000007604.1|UniProtKB=W5MLG7 W5MLG7 PTHR32463:SF0 L-FUCOSE KINASE L-FUCOSE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleotide-sugar metabolic process#GO:0009225;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086 kinase#PC00137;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000000888.1|UniProtKB=W5LY29 W5LY29 PTHR11254:SF66 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE ITCHY HOMOLOG ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000010069.1|UniProtKB=W5MVE4 W5MVE4 PTHR13902:SF53 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN 2 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;intracellular signal transduction#GO:0035556;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011860.1|UniProtKB=W5N1S7 W5N1S7 PTHR14735:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 134 COILED-COIL DOMAIN-CONTAINING PROTEIN 134 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000017125.1|UniProtKB=W5NKK2 W5NKK2 PTHR24403:SF82 ZINC FINGER PROTEIN ZINC FINGER-CONTAINING UBIQUITIN PEPTIDASE 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000003332.1|UniProtKB=W5M6D6 W5M6D6 PTHR11669:SF9 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 5 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA replication#GO:0006260 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;replication fork#GO:0005657;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 LEPOC|Ensembl=ENSLOCG00000003519.1|UniProtKB=W5M714 W5M714 PTHR11849:SF160 ETS ETS TRANSLOCATION VARIANT 5 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000010483.1|UniProtKB=W5MWU6 W5MWU6 PTHR11073:SF7 CALRETICULIN AND CALNEXIN CALMEGIN ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;protein folding#GO:0006457;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005575.1|UniProtKB=W5MEB9 W5MEB9 PTHR24232:SF21 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 regulation of intracellular signal transduction#GO:1902531;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;signaling#GO:0023052;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;positive regulation of MAPK cascade#GO:0043410;regulation of small GTPase mediated signal transduction#GO:0051056;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005402.1|UniProtKB=W5MDQ4 W5MDQ4 PTHR24390:SF211 ZINC FINGER PROTEIN ZINC FINGER PROTEIN XFIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000006006.1|UniProtKB=W5MFU8 W5MFU8 PTHR12307:SF15 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3C enzyme binding#GO:0019899;phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247;binding#GO:0005488;protein phosphatase binding#GO:0019903;carbohydrate binding#GO:0030246;protein binding#GO:0005515 regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010478.1|UniProtKB=W5MWT9 W5MWT9 PTHR12473:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-3 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005 LEPOC|Ensembl=ENSLOCG00000001334.1|UniProtKB=W5LZG1 W5LZG1 PTHR46914:SF1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;inflammatory response#GO:0006954;response to bacterium#GO:0009617;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;detection of stimulus#GO:0051606;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;defense response#GO:0006952;response to external stimulus#GO:0009605 cytosol#GO:0005829;canonical inflammasome complex#GO:0061702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000012367.1|UniProtKB=W5N3L2 W5N3L2 PTHR45930:SF2 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A3 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007354.1|UniProtKB=W5MKK1 W5MKK1 PTHR12622:SF47 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000277.1|UniProtKB=W5LVZ6 W5LVZ6 PTHR10903:SF112 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000016806.1|UniProtKB=W5NJG4 W5NJG4 PTHR22599:SF48 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 2 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase activator#PC00138 LEPOC|Ensembl=ENSLOCG00000003641.1|UniProtKB=W5M7G9 W5M7G9 PTHR23085:SF6 GH28348P JUNCTOPHILIN-1 membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529;cell periphery#GO:0071944;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000015654.1|UniProtKB=W5NF58 W5NF58 PTHR24198:SF207 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013794.1|UniProtKB=W5N8Q9 W5N8Q9 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;enzyme binding#GO:0019899 developmental process#GO:0032502;sperm-egg recognition#GO:0035036;cell-cell recognition#GO:0009988;cellular developmental process#GO:0048869;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;single fertilization#GO:0007338;oogenesis#GO:0048477;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;cell recognition#GO:0008037;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;binding of sperm to zona pellucida#GO:0007339;germ cell development#GO:0007281;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;fertilization#GO:0009566;gamete generation#GO:0007276;cell differentiation#GO:0030154 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007730.1|UniProtKB=W5MLX4 W5MLX4 PTHR23248:SF38 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 cellular component organization#GO:0016043;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;cellular process#GO:0009987;macromolecule localization#GO:0033036;endomembrane system organization#GO:0010256;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000654.1|UniProtKB=W5LX67 W5LX67 PTHR21344:SF1 RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000011883.1|UniProtKB=W5N1U7 W5N1U7 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 ISOFORM X1 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000015605.1|UniProtKB=W5NF07 W5NF07 PTHR46726:SF1 TWO PORE CHANNEL 3 TWO-PORE CALCIUM CHANNEL 3 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081 action potential#GO:0001508;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000002647.1|UniProtKB=W5M404 W5M404 PTHR13723:SF147 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 2 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000016198.1|UniProtKB=W5NH59 W5NH59 PTHR47966:SF37 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CATHEPSIN E-A-LIKE aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 aspartic protease#PC00053;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006311.1|UniProtKB=W5MGW5 W5MGW5 PTHR22619:SF4 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 4 Cul2-RING ubiquitin ligase complex#GO:0031462;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 LEPOC|Ensembl=ENSLOCG00000003730.1|UniProtKB=W5M7T8 W5M7T8 PTHR13914:SF0 PROLINE OXIDASE PROLINE DEHYDROGENASE-RELATED ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166 amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidase#PC00175 Huntington disease#P00029>Proline oxidase#G01529 LEPOC|Ensembl=ENSLOCG00000013764.1|UniProtKB=W5N8M4 W5N8M4 PTHR46021:SF6 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 2 molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;phosphatidylinositol phosphate binding#GO:1901981;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;lipid binding#GO:0008289;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 circulatory system development#GO:0072359;heart development#GO:0007507;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;system development#GO:0048731 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000003810.1|UniProtKB=W5M850 W5M850 PTHR12891:SF1 DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19 MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001310.1|UniProtKB=W5LZD4 W5LZD4 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 binding#GO:0005488;antigen binding#GO:0003823 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009281.1|UniProtKB=W5MSG3 W5MSG3 PTHR46402:SF2 SET AND MYND DOMAIN-CONTAINING PROTEIN 5 PROTEIN-LYSINE N-TRIMETHYLTRANSFERASE SMYD5 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cellular process#GO:0048523;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222 LEPOC|Ensembl=ENSLOCG00000000849.1|UniProtKB=W5LXU5 W5LXU5 PTHR10751:SF32 GUANYLATE BINDING PROTEIN ATLASTIN-3 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 G-protein#PC00020;heterotrimeric G-protein#PC00117 LEPOC|Ensembl=ENSLOCG00000003915.1|UniProtKB=W5M8I3 W5M8I3 PTHR10194:SF26 RAS GTPASE-ACTIVATING PROTEINS DISABLED HOMOLOG 2-INTERACTING PROTEIN GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 LEPOC|Ensembl=ENSLOCG00000000180.1|UniProtKB=W5LVP4 W5LVP4 PTHR24068:SF141 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 N ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;response to stimulus#GO:0050896;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Toll receptor signaling pathway#P00054>Ubc13#P01381 LEPOC|Ensembl=ENSLOCG00000015734.1|UniProtKB=W5NFG1 W5NFG1 PTHR10362:SF85 HISTIDINE AMMONIA-LYASE HISTIDINE AMMONIA-LYASE catalytic activity#GO:0003824;lyase activity#GO:0016829 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000017470.1|UniProtKB=W5NLR6 W5NLR6 PTHR13947:SF60 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000013518.1|UniProtKB=W5N7R0 W5N7R0 PTHR13434:SF0 PROTEIN CASC3 PROTEIN CASC3 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000004876.1|UniProtKB=W5MBV2 W5MBV2 PTHR13869:SF19 MYELIN P0 RELATED MYELIN PROTEIN ZERO-LIKE PROTEIN 1 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000002301.1|UniProtKB=W5M2T7 W5M2T7 NUBP2 PTHR23264:SF19 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2 binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;iron-sulfur cluster assembly#GO:0016226 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000008106.1|UniProtKB=W5MN87 W5MN87 PTHR46756:SF25 TRANSGELIN GAS2-LIKE PROTEIN 1 actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886;supramolecular fiber organization#GO:0097435;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;protein localization to cytoskeleton#GO:0044380;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;actin cytoskeleton organization#GO:0030036;actin filament organization#GO:0007015;intracellular protein localization#GO:0008104;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;protein localization to microtubule cytoskeleton#GO:0072698 microtubule cytoskeleton#GO:0015630;actomyosin#GO:0042641;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;stress fiber#GO:0001725;microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin cytoskeleton#GO:0015629;microtubule end#GO:1990752;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;microtubule#GO:0005874;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000008485.1|UniProtKB=W5MPL9 W5MPL9 PTHR24031:SF292 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX54 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000002747.1|UniProtKB=W5M4C3 W5M4C3 PTHR46523:SF1 DCTP PYROPHOSPHATASE 1 DCTP PYROPHOSPHATASE 1 nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;response to stress#GO:0006950;nucleobase-containing small molecule metabolic process#GO:0055086;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleotide catabolic process#GO:0009166 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000003135.1|UniProtKB=W5M5Q7 W5M5Q7 PTHR31432:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;intraciliary transport involved in cilium assembly#GO:0035735;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intraciliary transport particle#GO:0030990;intraciliary transport particle B#GO:0030992;cilium#GO:0005929;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000017387.1|UniProtKB=W5NLI3 W5NLI3 PTHR24231:SF25 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000000795.1|UniProtKB=W5LXN1 W5LXN1 PTHR13451:SF0 CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT MUS81 endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520 metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of biological process#GO:0048519;meiosis I#GO:0007127;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;meiotic cell cycle process#GO:1903046;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;mitotic cell cycle process#GO:1903047;DNA integrity checkpoint signaling#GO:0031570;double-strand break repair via break-induced replication#GO:0000727;resolution of meiotic recombination intermediates#GO:0000712;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;sexual reproduction#GO:0019953;cell communication#GO:0007154;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;homologous recombination#GO:0035825 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;endonuclease complex#GO:1905348;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000018286.1|UniProtKB=W5NP28 W5NP28 PTHR12002:SF182 CLAUDIN CLAUDIN-23 cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell junction organization#GO:0034330;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;apical junction complex#GO:0043296 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000010726.1|UniProtKB=W5MXP1 W5MXP1 PTHR46730:SF2 POLYCYSTIN-1 POLYCYSTIN-1 ISOFORM X1 monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000006589.1|UniProtKB=W5MHV1 W5MHV1 PTHR23077:SF69 AAA-FAMILY ATPASE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;polyubiquitin modification-dependent protein binding#GO:0031593;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;modification-dependent protein binding#GO:0140030 response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;autophagy#GO:0006914;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cell cycle process#GO:0022402;mitotic spindle organization#GO:0007052;response to stimulus#GO:0050896;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;autophagosome maturation#GO:0097352;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;transport#GO:0006810;establishment of localization#GO:0051234;spindle organization#GO:0007051;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;intracellular protein localization#GO:0008104;primary metabolic process#GO:0044238;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;protein-containing complex disassembly#GO:0032984;response to endoplasmic reticulum stress#GO:0034976;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;ERAD pathway#GO:0036503 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane#GO:0016020;cytosol#GO:0005829;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000009054.1|UniProtKB=W5MRN1 W5MRN1 PTHR11879:SF38 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012404.1|UniProtKB=W5N3R3 W5N3R3 PTHR24240:SF153 OPSIN GREEN-SENSITIVE OPSIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214;signal transduction#GO:0007165;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;response to radiation#GO:0009314;detection of stimulus#GO:0051606;biological regulation#GO:0065007 non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;9+0 non-motile cilium#GO:0097731;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944;neuron projection#GO:0043005 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004553.1|UniProtKB=W5MAP2 W5MAP2 PTHR13865:SF11 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN ZO-3 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 multicellular organismal-level homeostasis#GO:0048871;system process#GO:0003008;intracellular protein localization#GO:0008104;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cell-cell junction organization#GO:0045216;endothelial cell differentiation#GO:0045446;developmental process#GO:0032502;biological regulation#GO:0065007;epithelial cell differentiation#GO:0030855;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;tissue development#GO:0009888;blood circulation#GO:0008015;epithelium development#GO:0060429;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;tissue homeostasis#GO:0001894;anatomical structure development#GO:0048856;localization#GO:0051179;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;circulatory system process#GO:0003013;protein localization to cell junction#GO:1902414;cell development#GO:0048468;homeostatic process#GO:0042592;cell junction organization#GO:0034330;cell differentiation#GO:0030154;cellular component organization#GO:0016043 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000012239.1|UniProtKB=W5N347 W5N347 PTHR10497:SF0 60S RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN EL27 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000012707.1|UniProtKB=W5N4S7 W5N4S7 PTHR22942:SF39 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER DNA REPAIR PROTEIN RAD51 HOMOLOG 1 DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;response to stimulus#GO:0050896;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;chromosome organization involved in meiotic cell cycle#GO:0070192;protein-containing complex organization#GO:0043933;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;sexual reproduction#GO:0019953;mitotic recombination#GO:0006312;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;homologous recombination#GO:0035825;reproductive process#GO:0022414;DNA damage response#GO:0006974;DNA repair#GO:0006281;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000006401.1|UniProtKB=W5MH70 W5MH70 PTHR24372:SF67 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE-RICH REPEAT-CONTAINING G PROTEIN-COUPLED RECEPTOR 4 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of canonical Wnt signaling pathway#GO:0060828;response to hormone#GO:0009725;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to chemical#GO:0042221;positive regulation of Wnt signaling pathway#GO:0030177;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;hormone-mediated signaling pathway#GO:0009755;positive regulation of signaling#GO:0023056;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell communication#GO:0007154;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000010717.1|UniProtKB=W5MXL9 W5MXL9 PTHR12876:SF36 N4BP1-RELATED RIBONUCLEASE ZC3H12C-RELATED RNA binding#GO:0003723;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000006933.1|UniProtKB=W5MJ25 W5MJ25 PTHR12015:SF190 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE-RELATED cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000013264.1|UniProtKB=W5N6U1 W5N6U1 PTHR11474:SF3 TYROSINASE FAMILY MEMBER 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID OXIDASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 developmental process#GO:0032502;melanosome organization#GO:0032438;pigmentation#GO:0043473;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental pigmentation#GO:0048066;cellular process#GO:0009987;melanocyte differentiation#GO:0030318;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular pigmentation#GO:0033059;cell differentiation#GO:0030154 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;melanosome#GO:0042470;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000017616.1|UniProtKB=W5NM62 W5NM62 PTHR24232:SF107 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 183-LIKE-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017427.1|UniProtKB=W5NLM3 W5NLM3 PTHR12002:SF227 CLAUDIN CLAUDIN-RELATED transport#GO:0006810;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;paracellular transport#GO:0160184;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell junction assembly#GO:0034329;cellular process#GO:0009987;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000011878.1|UniProtKB=W5N1U3 W5N1U3 PTHR24026:SF133 FAT ATYPICAL CADHERIN-RELATED CADHERIN-RELATED FAMILY MEMBER 2 neuron development#GO:0048666;axonogenesis#GO:0007409;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;system development#GO:0048731;anatomical structure development#GO:0048856;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;axon development#GO:0061564 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000003530.1|UniProtKB=W5M715 W5M715 PTHR16195:SF16 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 14 LEPOC|Ensembl=ENSLOCG00000014324.1|UniProtKB=W5NAI0 W5NAI0 PTHR22811:SF60 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 3 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;Golgi organization#GO:0007030;cellular component organization#GO:0016043;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179 COPI-coated vesicle#GO:0030137;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle coat#GO:0030120;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;coated membrane#GO:0048475;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014470.1|UniProtKB=W5NB01 W5NB01 PTHR12606:SF16 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 3 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011237.1|UniProtKB=W5MZJ5 W5MZJ5 PTHR11866:SF6 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP4 SUBTYPE G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of response to stimulus#GO:0048583;cellular response to stimulus#GO:0051716;cellular response to alcohol#GO:0097306;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;negative regulation of inflammatory response#GO:0050728;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;cell communication#GO:0007154;response to hormone#GO:0009725;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;regulation of response to external stimulus#GO:0032101;negative regulation of response to external stimulus#GO:0032102;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to alcohol#GO:0097305;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;regulation of biological quality#GO:0065008 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 LEPOC|Ensembl=ENSLOCG00000017156.1|UniProtKB=W5NKP4 W5NKP4 PTHR23359:SF148 NUCLEOTIDE KINASE ADENYLATE KINASE 9 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 LEPOC|Ensembl=ENSLOCG00000006730.1|UniProtKB=W5MIB7 W5MIB7 PTHR24068:SF563 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein K48-linked ubiquitination#GO:0070936;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012732.1|UniProtKB=W5N4W5 W5N4W5 PTHR46532:SF13 MALE FERTILITY FACTOR KL5 DYNEIN AXONEMAL HEAVY CHAIN 5 LEPOC|Ensembl=ENSLOCG00000015948.1|UniProtKB=W5NG78 W5NG78 PTHR10202:SF24 PRESENILIN PRESENILIN-2 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 metabolic process#GO:0008152;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;cell surface receptor signaling pathway#GO:0007166;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;monoatomic ion homeostasis#GO:0050801;membrane protein proteolysis#GO:0033619;signal transduction#GO:0007165;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;membrane protein ectodomain proteolysis#GO:0006509;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;proteolysis#GO:0006508;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;cell communication#GO:0007154;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052 membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;catalytic complex#GO:1902494 aspartic protease#PC00053;protease#PC00190 Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Notch signaling pathway#P00045>Pen-2#P01113;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129 LEPOC|Ensembl=ENSLOCG00000011991.1|UniProtKB=W5N285 W5N285 PTHR28604:SF1 FAMILY NOT NAMED PROLINE-RICH PROTEIN 29 LEPOC|Ensembl=ENSLOCG00000014096.1|UniProtKB=W5N9Q7 W5N9Q7 PTHR34105:SF1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000007626.1|UniProtKB=W5MLJ8 W5MLJ8 PTHR22996:SF2 MAHOGUNIN E3 UBIQUITIN-PROTEIN LIGASE MGRN1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;localization#GO:0051179;cell communication#GO:0007154;cellular localization#GO:0051641;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;cellular process#GO:0009987;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;intracellular transport#GO:0046907 intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015115.1|UniProtKB=W5ND92 W5ND92 PTHR12011:SF277 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G4 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002474.1|UniProtKB=W5M3F1 W5M3F1 PTHR45672:SF2 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED PROTEIN DISULFIDE-ISOMERASE A5 isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000005729.1|UniProtKB=W5MEV0 W5MEV0 PTHR11767:SF16 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 1 transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;GABA-B receptor II signaling#P05731>K channel#P05758;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083 LEPOC|Ensembl=ENSLOCG00000005189.1|UniProtKB=W5MCY8 W5MCY8 PTHR46319:SF6 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;early endosome membrane#GO:0031901;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000000350.1|UniProtKB=W5LW75 W5LW75 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010438.1|UniProtKB=W5MWN2 W5MWN2 PTHR24247:SF30 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594 cell communication#GO:0007154;response to nitrogen compound#GO:1901698;G protein-coupled receptor signaling pathway#GO:0007186;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;trans-synaptic signaling#GO:0099537;response to oxygen-containing compound#GO:1901700;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;dendrite#GO:0030425;dendritic tree#GO:0097447 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414 LEPOC|Ensembl=ENSLOCG00000014037.1|UniProtKB=W5N9J3 W5N9J3 PTHR15390:SF1 NEUROMEDIN-U NEUROMEDIN U LEPOC|Ensembl=ENSLOCG00000009282.1|UniProtKB=W5MSG8 W5MSG8 PTHR10747:SF26 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;P53-like transcription factor#PC00253 LEPOC|Ensembl=ENSLOCG00000017019.1|UniProtKB=W5NK79 W5NK79 PTHR43407:SF1 GLUTAMINE SYNTHETASE LENGSIN ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;homeostatic process#GO:0042592;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;response to nutrient levels#GO:0031667;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;chemical homeostasis#GO:0048878 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483 LEPOC|Ensembl=ENSLOCG00000008911.1|UniProtKB=W5MR44 W5MR44 PTHR22870:SF335 REGULATOR OF CHROMOSOME CONDENSATION RCC1 AND BTB DOMAIN CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000000930.1|UniProtKB=W5LY49 W5LY49 PTHR13140:SF781 MYOSIN MYOSIN-11 isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;membrane#GO:0016020 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000008552.1|UniProtKB=W5MPU0 W5MPU0 PTHR11653:SF4 PARVALBUMIN ALPHA ONCOMODULIN-2 calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000013440.1|UniProtKB=W5N7G2 W5N7G2 PTHR45659:SF2 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000014615.1|UniProtKB=W5NBH6 W5NBH6 PTHR10807:SF34 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR6 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;dephosphorylation#GO:0016311;lipid modification#GO:0030258 nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000007740.1|UniProtKB=W5MLY9 W5MLY9 PTHR11394:SF137 TASTE RECEPTOR TYPE 2 OLFACTORY RECEPTOR CLASS A-LIKE PROTEIN 4-RELATED transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012392.1|UniProtKB=W5N3Q5 W5N3Q5 PTHR19288:SF46 4-NITROPHENYLPHOSPHATASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004776.1|UniProtKB=W5MBM6 W5MBM6 PTHR15729:SF13 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 32 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of synapse structure or activity#GO:0050803;regulation of dendritic spine morphogenesis#GO:0061001;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of postsynapse organization#GO:0099175;cellular response to stimulus#GO:0051716;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;regulation of synapse assembly#GO:0051963;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;cellular process#GO:0009987 neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;organelle#GO:0043226;postsynapse#GO:0098794;cell junction#GO:0030054;postsynaptic density#GO:0014069 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 Gonadotropin-releasing hormone receptor pathway#P06664>RICS#G06882;Gonadotropin-releasing hormone receptor pathway#P06664>RICS#P06765;Gonadotropin-releasing hormone receptor pathway#P06664>RICS#G06669 LEPOC|Ensembl=ENSLOCG00000007722.1|UniProtKB=W5MLW3 W5MLW3 PTHR24418:SF91 TYROSINE-PROTEIN KINASE CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000008852.1|UniProtKB=W5MQV8 W5MQV8 LSM6 PTHR11021:SF1 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA splicing, via transesterification reactions#GO:0000375;rRNA processing#GO:0006364;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467 spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;P-body#GO:0000932;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U6 snRNP#GO:0005688;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;U4/U6 x U5 tri-snRNP complex#GO:0046540;ribonucleoprotein granule#GO:0035770 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000005457.1|UniProtKB=W5MDY7 W5MDY7 PTHR24351:SF43 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;cell communication#GO:0007154;TORC1 signaling#GO:0038202;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;TOR signaling#GO:0031929;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 CCKR signaling map#P06959>RSK1/2#P07153;PDGF signaling pathway#P00047>p90RSK#P01142;Ras Pathway#P04393>p90RSK#P04541;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Interleukin signaling pathway#P00036>p90RSK#P00964 LEPOC|Ensembl=ENSLOCG00000015619.1|UniProtKB=W5NF17 W5NF17 PTHR21490:SF2 ENKURIN-RELATED ENKURIN DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic microtubule#GO:0005881;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012969.1|UniProtKB=W5N5R4 W5N5R4 PTHR18945:SF489 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;transmembrane transport#GO:0055085;trans-synaptic signaling#GO:0099537;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 LEPOC|Ensembl=ENSLOCG00000006567.1|UniProtKB=W5MHR9 W5MHR9 PTHR12086:SF12 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER B molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 biological regulation#GO:0065007;regulation of calcium ion transport#GO:0051924;regulation of signal transduction#GO:0009966;regulation of monoatomic ion transport#GO:0043269;cellular process#GO:0009987;regulation of calcineurin-NFAT signaling cascade#GO:0070884;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of response to stimulus#GO:0048583;flagellated sperm motility#GO:0030317;regulation of cell communication#GO:0010646;reproductive process#GO:0022414;regulation of calcium-mediated signaling#GO:0050848;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of metal ion transport#GO:0010959;sperm motility#GO:0097722;regulation of biological process#GO:0050789;cilium-dependent cell motility#GO:0060285;regulation of signaling#GO:0023051;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;regulation of intracellular signal transduction#GO:1902531 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;cytoplasmic microtubule#GO:0005881 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000005363.1|UniProtKB=W5MDM4 W5MDM4 PTHR11477:SF3 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 2 transcription regulator activity#GO:0140110;transcription elongation factor activity#GO:0003711 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000784.1|UniProtKB=W5LXL2 W5LXL2 PTHR45134:SF5 OS08G0543275 PROTEIN G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000006688.1|UniProtKB=W5MI71 W5MI71 PTHR10363:SF2 BLEOMYCIN HYDROLASE BLEOMYCIN HYDROLASE aminopeptidase activity#GO:0004177;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238 sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;carboxylic acid catabolic process#GO:0046395;response to chemical#GO:0042221;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;sulfur compound catabolic process#GO:0044273;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;response to toxic substance#GO:0009636;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000012485.1|UniProtKB=W5N411 W5N411 PTHR21319:SF53 RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 P53 pathway feedback loops 1#P04392>Pirh-2#G04684;P53 pathway feedback loops 1#P04392>Pirh-2#P04538 LEPOC|Ensembl=ENSLOCG00000010883.1|UniProtKB=W5MY84 W5MY84 PTHR19433:SF127 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED NOVEL IMMUNE-TYPE RECEPTOR 12 ISOFORM X1-RELATED response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000014038.1|UniProtKB=W5N9J4 W5N9J4 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000016679.1|UniProtKB=W5NIZ8 W5NIZ8 PTHR24073:SF269 DRAB5-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 27 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 LEPOC|Ensembl=ENSLOCG00000018026.1|UniProtKB=W5NNB8 W5NNB8 PTHR34072:SF73 ENZYMATIC POLYPROTEIN-RELATED REVERSE TRANSCRIPTASE RNASE H-LIKE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009524.1|UniProtKB=W5MTD3 W5MTD3 PTHR11309:SF75 FRIZZLED FRIZZLED-6 signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089;Wnt-protein binding#GO:0017147;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;signaling#GO:0023052;biological regulation#GO:0065007;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>Frizzled#P00475;Wnt signaling pathway#P00057>Frizzled#P01428;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 LEPOC|Ensembl=ENSLOCG00000018146.1|UniProtKB=W5NNN8 W5NNN8 PTHR24366:SF174 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000008329.1|UniProtKB=W5MP06 W5MP06 PTHR21353:SF10 FAMILY NOT NAMED CARDIOTROPHIN-LIKE CYTOKINE FACTOR 1 receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway via STAT#GO:0097696;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000010687.1|UniProtKB=W5MXJ4 W5MXJ4 PTHR43416:SF5 DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000000985.1|UniProtKB=W5LYA1 W5LYA1 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;serine hydrolase activity#GO:0017171;peptidase activity#GO:0008233;catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017975.1|UniProtKB=W5NN67 W5NN67 PTHR24231:SF16 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 6 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013960.1|UniProtKB=W5N999 W5N999 PTHR48421:SF1 MYCBP-ASSOCIATED PROTEIN MYCBP-ASSOCIATED PROTEIN LEPOC|Ensembl=ENSLOCG00000011029.1|UniProtKB=W5MYS7 W5MYS7 PTHR46458:SF1 BLR2807 PROTEIN NEUROGLOBIN molecular carrier activity#GO:0140104;small molecule binding#GO:0036094;binding#GO:0005488 establishment of localization#GO:0051234;localization#GO:0051179;response to hypoxia#GO:0001666;transport#GO:0006810;response to stimulus#GO:0050896;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004992.1|UniProtKB=W5MCA2 W5MCA2 PTHR46346:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011193.1|UniProtKB=W5MZF0 W5MZF0 PTHR16214:SF3 TRANSMEMBRANE PROTEIN 260 PROTEIN O-MANNOSYL-TRANSFERASE TMEM260 LEPOC|Ensembl=ENSLOCG00000003577.1|UniProtKB=W5M787 W5M787 PTHR12801:SF158 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 4 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;nucleic acid biosynthetic process#GO:0141187;DNA catabolic process#GO:0006308;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 exoribonuclease#PC00099;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001963.1|UniProtKB=W5M1L3 W5M1L3 PTHR24369:SF172 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011440.1|UniProtKB=W5N0A7 W5N0A7 PTHR13489:SF0 MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN chromatin binding#GO:0003682;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261 LEPOC|Ensembl=ENSLOCG00000011368.1|UniProtKB=W5N020 W5N020 PTHR12768:SF4 BECLIN 1 BECLIN-1 binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;phosphatidylinositol 3-kinase binding#GO:0043548;protein binding#GO:0005515 response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;intracellular transport#GO:0046907;autophagy of mitochondrion#GO:0000422;cellular response to starvation#GO:0009267;transport#GO:0006810;cellular response to nutrient levels#GO:0031669;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;mitophagy#GO:0000423;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;organelle assembly#GO:0070925;localization#GO:0051179;vacuole organization#GO:0007033;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome organization#GO:1905037;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;cellular component organization#GO:0016043;response to stimulus#GO:0050896;late endosome to vacuole transport#GO:0045324;cellular response to stress#GO:0033554;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;phosphatidylinositol 3-kinase complex, class III#GO:0035032;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000008528.1|UniProtKB=W5MPS1 W5MPS1 PTHR43157:SF54 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 12 ISOFORM X1-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000000580.1|UniProtKB=W5LWY5 W5LWY5 PTHR45879:SF4 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CAMP-RESPONSIVE ELEMENT MODULATOR transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 intracellular signaling cassette#GO:0141124;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 Apoptosis signaling pathway#P00006>ATF#P00302;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;CCKR signaling map#P06959>ICER#P07027;Enkephalin release#P05913>CREB#P05971;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 LEPOC|Ensembl=ENSLOCG00000010683.1|UniProtKB=W5MXH7 W5MXH7 PTHR12356:SF18 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 2 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003927.1|UniProtKB=W5M8I4 W5M8I4 PTHR12919:SF41 30S RIBOSOMAL PROTEIN S16 SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000011012.1|UniProtKB=W5MYQ6 W5MYQ6 PTHR24327:SF31 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;embryo development ending in birth or egg hatching#GO:0009792;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000005530.1|UniProtKB=W5ME67 W5ME67 PTHR12225:SF0 ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;proteasome complex#GO:0000502 LEPOC|Ensembl=ENSLOCG00000008935.1|UniProtKB=W5MR73 W5MR73 PTHR23320:SF54 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 5 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004763.1|UniProtKB=W5MBF5 W5MBF5 PTHR32315:SF3 ADENINE PHOSPHORIBOSYLTRANSFERASE ADENINE PHOSPHORIBOSYLTRANSFERASE heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;ribonucleotide binding#GO:0032553;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;glycosyltransferase activity#GO:0016757;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;pentosyltransferase activity#GO:0016763 purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleobase metabolic process#GO:0006144;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate biosynthetic process#GO:0090407;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphoribosyl transferase#P02810 LEPOC|Ensembl=ENSLOCG00000006299.1|UniProtKB=W5MGU9 W5MGU9 PTHR17615:SF7 PROTEIN FAM189A PROTEIN ENTREP3 LEPOC|Ensembl=ENSLOCG00000001271.1|UniProtKB=W5LZ98 W5LZ98 PTHR12979:SF5 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;CCR4-NOT complex#GO:0030014 LEPOC|Ensembl=ENSLOCG00000014083.1|UniProtKB=W5N9R4 W5N9R4 PTHR12295:SF9 FURRY-RELATED PROTEIN FURRY HOMOLOG-LIKE cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502 cell division site#GO:0032153;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014016.1|UniProtKB=W5N9G9 W5N9G9 PTHR47574:SF3 CANCER-RELATED REGULATOR OF ACTIN DYNAMICS CAPPING PROTEIN-INHIBITING REGULATOR OF ACTIN DYNAMICS tissue homeostasis#GO:0001894;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;homeostatic process#GO:0042592;regulation of actin filament depolymerization#GO:0030834;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;system process#GO:0003008;regulation of protein depolymerization#GO:1901879;multicellular organismal-level homeostasis#GO:0048871;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;digestion#GO:0007586;multicellular organismal process#GO:0032501;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;epithelial structure maintenance#GO:0010669;regulation of actin cytoskeleton organization#GO:0032956;anatomical structure homeostasis#GO:0060249;positive regulation of cellular component biogenesis#GO:0044089 LEPOC|Ensembl=ENSLOCG00000000232.1|UniProtKB=W5LVU9 W5LVU9 PTHR24399:SF32 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 37 sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008990.1|UniProtKB=W5MRE3 W5MRE3 PTHR10671:SF106 EPITHELIAL MEMBRANE PROTEIN-RELATED LENS FIBER MEMBRANE INTRINSIC PROTEIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000017333.1|UniProtKB=W5NLC9 W5NLC9 PTHR13568:SF9 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 203 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013835.1|UniProtKB=W5N8V1 W5N8V1 PTHR47979:SF110 DRAB11-RELATED RAS-RELATED PROTEIN RAB-11A catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;pigmentation#GO:0043473;organelle localization#GO:0051640;protein localization to cell junction#GO:1902414;secretion#GO:0046903;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;transport#GO:0006810;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;endosome to plasma membrane protein transport#GO:0099638;vesicle localization#GO:0051648;macromolecule localization#GO:0033036;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;protein transport#GO:0015031;secretion by cell#GO:0032940;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;export from cell#GO:0140352;establishment of organelle localization#GO:0051656;endocytic recycling#GO:0032456;intracellular protein transport#GO:0006886;protein localization to cell periphery#GO:1990778;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;exocytosis#GO:0006887;endosomal transport#GO:0016197;protein localization to synapse#GO:0035418;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;cellular pigmentation#GO:0033059;establishment of vesicle localization#GO:0051650;vesicle-mediated transport#GO:0016192 endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;cell junction#GO:0030054;postsynapse#GO:0098794;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000004245.1|UniProtKB=W5M9L6 W5M9L6 PTHR11247:SF82 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 DOLICHYLDIPHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006121.1|UniProtKB=W5MG89 W5MG89 PTHR45618:SF57 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED DICARBOXYLATE CARRIER UCP2 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;intracellular transport#GO:0046907;temperature homeostasis#GO:0001659;multicellular organismal-level homeostasis#GO:0048871;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;response to stress#GO:0006950;response to temperature stimulus#GO:0009266;multicellular organismal process#GO:0032501;adaptive thermogenesis#GO:1990845;mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;response to abiotic stimulus#GO:0009628;homeostatic process#GO:0042592;response to stimulus#GO:0050896;mitochondrial transport#GO:0006839;response to cold#GO:0009409 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000016960.1|UniProtKB=W5NK08 W5NK08 PTHR31057:SF0 E3 UFM1-PROTEIN LIGASE 1 E3 UFM1-PROTEIN LIGASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 response to stimulus#GO:0050896;catabolic process#GO:0009056;macroautophagy#GO:0016236;response to stress#GO:0006950;reticulophagy#GO:0061709;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;autophagy#GO:0006914;process utilizing autophagic mechanism#GO:0061919;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000014878.1|UniProtKB=W5NCG2 W5NCG2 PTHR22747:SF14 NUCLEOPLASMIN NUCLEOPLASMIN-2 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015644.1|UniProtKB=W5NF50 W5NF50 PTHR46006:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A NEUROEPITHELIAL CELL-TRANSFORMING GENE 1 PROTEIN regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009181.1|UniProtKB=W5MS44 W5MS44 PTHR23339:SF74 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14B hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;regulation of mitotic cell cycle phase transition#GO:1901990;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;regulation of cell cycle phase transition#GO:1901987;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;regulation of cell cycle#GO:0051726 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012025.1|UniProtKB=W5N2D1 W5N2D1 PTHR43477:SF4 DIHYDROANTICAPSIN 7-DEHYDROGENASE DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 6 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 biosynthetic process#GO:0009058;siderophore biosynthetic process#GO:0019290;cellular process#GO:0009987;peptide metabolic process#GO:0006518;secondary metabolic process#GO:0019748;metabolic process#GO:0008152;secondary metabolite biosynthetic process#GO:0044550;siderophore metabolic process#GO:0009237 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004950.1|UniProtKB=W5MC51 W5MC51 PTHR11616:SF241 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 2 monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;glycine transmembrane transporter activity#GO:0015187;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175 monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;nitrogen compound transport#GO:0071705;synaptic signaling#GO:0099536;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;import into cell#GO:0098657;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;glycine transport#GO:0015816 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000016609.1|UniProtKB=W5NIQ9 W5NIQ9 PTHR19336:SF10 UNCHARACTERIZED DUF1167 CENTROSOMAL PROTEIN CEP57L1 cytoskeletal protein binding#GO:0008092;cytoskeletal adaptor activity#GO:0008093;tubulin binding#GO:0015631;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;microtubule binding#GO:0008017;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;organelle organization#GO:0006996;attachment of spindle microtubules to kinetochore#GO:0008608;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004856.1|UniProtKB=W5MBS2 W5MBS2 PTHR24412:SF187 KELCH PROTEIN KELCH-LIKE PROTEIN 35 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015337.1|UniProtKB=W5NE15 W5NE15 PTHR20929:SF11 LUNG ADENOMA SUSCEPTIBILITY 1-RELATED DYNEIN AXONEMAL INTERMEDIATE CHAIN 7 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 axoneme#GO:0005930;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000015615.1|UniProtKB=W5NF15 W5NF15 PTHR22776:SF88 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MAL, T CELL DIFFERENTIATION PROTEIN A, TANDEM DUPLICATE 1 structural molecule activity#GO:0005198 establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;multicellular organismal process#GO:0032501;protein insertion into membrane#GO:0051205;nervous system development#GO:0007399;biological regulation#GO:0065007;membrane organization#GO:0061024;developmental process#GO:0032502;establishment of localization#GO:0051234;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;myelination#GO:0042552;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;localization within membrane#GO:0051668;cellular localization#GO:0051641;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane raft#GO:0045121;membrane#GO:0016020;apical plasma membrane#GO:0016324;membrane microdomain#GO:0098857;apical part of cell#GO:0045177 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010218.1|UniProtKB=W5MVW4 W5MVW4 PTHR43691:SF10 URIDINE PHOSPHORYLASE URIDINE PHOSPHORYLASE 1 pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 nucleoside catabolic process#GO:0009164;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 LEPOC|Ensembl=ENSLOCG00000013129.1|UniProtKB=W5N6D6 W5N6D6 PTHR10574:SF36 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-2 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component assembly#GO:0022607;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron differentiation#GO:0030182;substrate adhesion-dependent cell spreading#GO:0034446;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;cell adhesion#GO:0007155;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;axon guidance#GO:0007411;axon development#GO:0061564;tissue development#GO:0009888;extracellular matrix assembly#GO:0085029;cell migration#GO:0016477;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;anatomical structure development#GO:0048856;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;system development#GO:0048731 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;basement membrane#GO:0005604;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000012989.1|UniProtKB=W5N5T9 W5N5T9 PTHR24068:SF147 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 K ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000016047.1|UniProtKB=W5NGK8 W5NGK8 PTHR13793:SF17 PHD FINGER PROTEINS BROMODOMAIN-CONTAINING PROTEIN 1 chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566 chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000006472.1|UniProtKB=W5MHF6 W5MHF6 PTHR25462:SF306 BONUS, ISOFORM C-RELATED E3 UBIQUITIN-PROTEIN LIGASE MIDLINE-1-LIKE acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000005567.1|UniProtKB=W5MEC0 W5MEC0 PTHR24028:SF263 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 1 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000015383.1|UniProtKB=W5NE72 W5NE72 PTHR10185:SF9 PHOSPHOLIPASE D - RELATED INACTIVE PHOSPHOLIPASE D5 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000016509.1|UniProtKB=W5NID3 W5NID3 PTHR10052:SF1 60S RIBOSOMAL PROTEIN L18A LARGE RIBOSOMAL SUBUNIT PROTEIN EL20 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000003460.1|UniProtKB=W5M6V9 W5M6V9 PTHR12655:SF10 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL hydrolase activity#GO:0016787;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;deacylase activity#GO:0160215;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 LEPOC|Ensembl=ENSLOCG00000016115.1|UniProtKB=W5NGU7 W5NGU7 PTHR24025:SF31 DESMOGLEIN FAMILY MEMBER NEURAL-CADHERIN metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000002074.1|UniProtKB=W5M226 W5M226 PTHR24031:SF54 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX10-RELATED gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008798.1|UniProtKB=W5MQP9 W5MQP9 PTHR13231:SF3 MITOCHONDRIAL RIBOSOMAL PROTEIN S31 SMALL RIBOSOMAL SUBUNIT PROTEIN MS31 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000012651.1|UniProtKB=W5N4L0 W5N4L0 PTHR11476:SF7 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000010705.1|UniProtKB=W5MXK2 W5MXK2 PTHR15949:SF3 TESTIS-EXPRESSED PROTEIN 264 TESTIS-EXPRESSED PROTEIN 264 reticulophagy#GO:0061709;response to stress#GO:0006950;autophagy#GO:0006914;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;macroautophagy#GO:0016236;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;process utilizing autophagic mechanism#GO:0061919 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membraneless organelle#GO:0043228;vacuolar membrane#GO:0005774;nucleus#GO:0005634;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;vacuole#GO:0005773;endomembrane system#GO:0012505 LEPOC|Ensembl=ENSLOCG00000010870.1|UniProtKB=W5MY67 W5MY67 PTHR14768:SF4 UPF0338 PROTEIN SYNAPSE DIFFERENTIATION-INDUCING GENE PROTEIN 1-LIKE membrane#GO:0016020;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000014447.1|UniProtKB=W5NAX3 W5NAX3 SEC61A1 PTHR10906:SF19 SECY/SEC61-ALPHA FAMILY MEMBER PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;transmembrane protein transporter activity#GO:0008320 SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;localization within membrane#GO:0051668;protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;rough endoplasmic reticulum#GO:0005791;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005847.1|UniProtKB=W5MFD8 W5MFD8 PTHR10816:SF9 MYELIN TRANSCRIPTION FACTOR 1-RELATED SUPPRESSION OF TUMORIGENICITY 18 PROTEIN DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016937.1|UniProtKB=W5NJX6 W5NJX6 PTHR15405:SF8 PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR 1 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004033.1|UniProtKB=W5M8W1 W5M8W1 PTHR23037:SF42 CYTOKINE RECEPTOR INTERLEUKIN-4 RECEPTOR SUBUNIT ALPHA ISOFORM 2 PRECURSOR molecular transducer activity#GO:0060089;protein binding#GO:0005515;growth factor binding#GO:0019838;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896 regulation of cellular process#GO:0050794;response to cytokine#GO:0034097;response to stimulus#GO:0050896;response to chemical#GO:0042221;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010147.1|UniProtKB=W5MVL0 W5MVL0 PTHR11639:SF147 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-P calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515 cell migration#GO:0016477;endothelial cell migration#GO:0043542;cell motility#GO:0048870;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061;calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000013159.1|UniProtKB=W5N6F6 W5N6F6 PTHR10574:SF197 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-1 cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;substrate adhesion-dependent cell spreading#GO:0034446;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular component assembly#GO:0022607;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;extracellular structure organization#GO:0043062;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;extracellular matrix assembly#GO:0085029;cell migration#GO:0016477;multicellular organismal process#GO:0032501;tissue development#GO:0009888;axon guidance#GO:0007411;axon development#GO:0061564;external encapsulating structure organization#GO:0045229;system development#GO:0048731;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;cell motility#GO:0048870 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;basement membrane#GO:0005604 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000017839.1|UniProtKB=W5NMT3 W5NMT3 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014738.1|UniProtKB=W5NBY8 W5NBY8 PTHR12400:SF55 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE A phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000013849.1|UniProtKB=W5N8X5 W5N8X5 PTHR45712:SF2 AGAP008170-PA ASPORIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000002285.1|UniProtKB=W5M2R4 W5M2R4 PTHR12981:SF0 ZINC FINGER PROTEIN-LIKE 1 ZINC FINGER PROTEIN-LIKE 1 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010879.1|UniProtKB=W5MY75 W5MY75 PTHR22950:SF244 AMINO ACID TRANSPORTER NEUTRAL AMINO ACID TRANSPORTER 9 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774 amino acid transporter#PC00046;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000002142.1|UniProtKB=W5M281 W5M281 PTHR11534:SF3 MYOGENIC FACTOR MYOGENIC FACTOR 5 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;muscle tissue development#GO:0060537;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;tissue development#GO:0009888;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;skeletal muscle tissue development#GO:0007519;regulation of cell development#GO:0060284;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;animal organ development#GO:0048513;muscle organ development#GO:0007517;striated muscle tissue development#GO:0014706;positive regulation of cell differentiation#GO:0045597 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013066.1|UniProtKB=W5N639 W5N639 PTHR23342:SF22 N-ACETYLGLUTAMATE SYNTHASE N-ACETYLGLUTAMATE SYNTHASE, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, carboxyl group as acceptor#GO:0016774 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 Arginine biosynthesis#P02728>N-acetylglutamate synthase#P02848 LEPOC|Ensembl=ENSLOCG00000001997.1|UniProtKB=W5M1R3 W5M1R3 PTHR11878:SF26 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER 4 ISOFORM B antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;export from cell#GO:0140352;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082 axon#GO:0030424;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000011916.1|UniProtKB=W5N1Z0 W5N1Z0 PTHR11309:SF34 FRIZZLED FRIZZLED-2 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147 non-canonical Wnt signaling pathway#GO:0035567;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475;Wnt signaling pathway#P00057>Frizzled#P01428;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 LEPOC|Ensembl=ENSLOCG00000015043.1|UniProtKB=W5ND12 W5ND12 PTHR16228:SF25 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 2 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013139.1|UniProtKB=W5N6C5 W5N6C5 PTHR13009:SF22 HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1 ACTIVATOR OF 90 KDA HEAT SHOCK PROTEIN ATPASE HOMOLOG 1 ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000017864.1|UniProtKB=W5NMV8 W5NMV8 PTHR24390:SF260 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001731.1|UniProtKB=W5M0U7 W5M0U7 PTHR24412:SF396 KELCH PROTEIN INFLUENZA VIRUS NS1A-BINDING PROTEIN ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007138.1|UniProtKB=W5MJT1 W5MJT1 PTHR31402:SF2 UPF0711 PROTEIN C18ORF21 RIBONUCLEASE MRP PROTEIN SUBUNIT P24 LEPOC|Ensembl=ENSLOCG00000005448.1|UniProtKB=W5MDW2 W5MDW2 PTHR22998:SF1 SARM1 NAD(+) HYDROLASE SARM1 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;pyridine nucleotide catabolic process#GO:0019364;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195 cell projection#GO:0042995;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell body#GO:0044297;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;neuron projection#GO:0043005 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005794.1|UniProtKB=W5MF40 W5MF40 PTHR23226:SF248 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 648 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008716.1|UniProtKB=W5MQH9 W5MQH9 PTHR14149:SF10 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP3 protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;cytoskeletal protein binding#GO:0008092;enzyme activator activity#GO:0008047;calmodulin binding#GO:0005516 cellular process#GO:0009987;actomyosin contractile ring assembly#GO:0000915;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;mitotic cell cycle process#GO:1903047;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cell division#GO:0051301;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell cycle#GO:0007049;actomyosin structure organization#GO:0031032;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;cytokinetic process#GO:0032506;cytokinesis#GO:0000910;cortical cytoskeleton organization#GO:0030865;supramolecular fiber organization#GO:0097435;mitotic cytokinetic process#GO:1902410;cortical actin cytoskeleton organization#GO:0030866;cytoskeleton-dependent cytokinesis#GO:0061640 cell cortex#GO:0005938;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000015787.1|UniProtKB=W5NFN4 W5NFN4 PTHR10751:SF42 GUANYLATE BINDING PROTEIN ATLASTIN-2 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 G-protein#PC00020;heterotrimeric G-protein#PC00117 LEPOC|Ensembl=ENSLOCG00000005479.1|UniProtKB=W5ME05 W5ME05 PTHR11412:SF83 MACROGLOBULIN / COMPLEMENT COMPLEMENT C5 molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;cytokine activity#GO:0005125;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;chemokine activity#GO:0008009;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of immune response#GO:0050776;chemotaxis#GO:0006935;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;locomotion#GO:0040011;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;complement activation#GO:0006956;immune response#GO:0006955;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;response to other organism#GO:0051707;adaptive immune response#GO:0002250;immune system process#GO:0002376;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;humoral immune response#GO:0006959;immune effector process#GO:0002252;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;response to chemical#GO:0042221;taxis#GO:0042330;defense response to other organism#GO:0098542 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000007942.1|UniProtKB=W5MMP6 W5MMP6 PTHR10372:SF6 PLAKOPHILLIN-RELATED CATENIN DELTA-1 protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;nucleus#GO:0005634;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 intermediate filament binding protein#PC00130;intermediate filament#PC00129;cytoskeletal protein#PC00085 Cadherin signaling pathway#P00012>P120#P00473 LEPOC|Ensembl=ENSLOCG00000007056.1|UniProtKB=W5MJJ2 W5MJJ2 PTHR46108:SF1 BLUE CHEESE WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 3 macroautophagy#GO:0016236;process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;autophagy#GO:0006914;cellular process#GO:0009987;metabolic process#GO:0008152 LEPOC|Ensembl=ENSLOCG00000014561.1|UniProtKB=W5NBB0 W5NBB0 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;organelle assembly#GO:0070925;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000013507.1|UniProtKB=W5N7P5 W5N7P5 PTHR21656:SF2 MALE-SPECIFIC LETHAL-1 PROTEIN MALE-SPECIFIC LETHAL 1 HOMOLOG chromatin binding#GO:0003682;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000014333.1|UniProtKB=W5NAJ4 W5NAJ4 PTHR11036:SF14 SEMAPHORIN SEMAPHORIN-4B signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to chemical#GO:0042221;taxis#GO:0042330;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;neuron development#GO:0048666;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;chemotaxis#GO:0006935;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;locomotion#GO:0040011 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000002707.1|UniProtKB=W5M479 W5M479 PTHR24025:SF31 DESMOGLEIN FAMILY MEMBER NEURAL-CADHERIN calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000002069.1|UniProtKB=W5M1Z6 W5M1Z6 PTHR15703:SF3 RIKEN CDNA 4931406P16 GENE GRANULE ASSOCIATED RAC AND RHOG EFFECTOR PROTEIN 1 protein-containing complex binding#GO:0044877;binding#GO:0005488 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;Rac protein signal transduction#GO:0016601;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 LEPOC|Ensembl=ENSLOCG00000007217.1|UniProtKB=W5MK29 W5MK29 PTHR11475:SF63 OXIDASE/PEROXIDASE EOSINOPHIL PEROXIDASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 defense response#GO:0006952;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000009435.1|UniProtKB=W5MT01 W5MT01 PTHR10264:SF117 BAND 7 PROTEIN-RELATED ERYTHROCYTE BAND 7 INTEGRAL MEMBRANE PROTEIN-LIKE ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000004047.1|UniProtKB=W5M8X1 W5M8X1 PTHR12560:SF58 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010132.1|UniProtKB=W5MVJ0 W5MVJ0 PTHR23159:SF47 CENTROSOMAL PROTEIN 2 ROOTLETIN-LIKE COILED-COIL DOMAIN-CONTAINING PROTEIN chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000003474.1|UniProtKB=W5M6X6 W5M6X6 PTHR48012:SF22 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE 24 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of cell migration#GO:0030334;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell motility#GO:2000145 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005153.1|UniProtKB=W5MCU4 W5MCU4 PTHR46013:SF9 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008007.1|UniProtKB=W5MMY3 W5MMY3 PTHR11831:SF5 30S 40S RIBOSOMAL PROTEIN SMALL RIBOSOMAL SUBUNIT PROTEIN US4 structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085 cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000015077.1|UniProtKB=W5ND48 W5ND48 PTHR21556:SF2 TRESLIN TRESLIN binding#GO:0005488;chromatin binding#GO:0003682 signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;regulation of DNA-templated DNA replication initiation#GO:0030174;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;mitotic DNA replication checkpoint signaling#GO:0033314;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of DNA replication#GO:0006275;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;regulation of DNA-templated DNA replication#GO:0090329;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000008807.1|UniProtKB=W5MQQ9 W5MQQ9 PTHR45767:SF10 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O1-A-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000005994.1|UniProtKB=W5MFT3 W5MFT3 PTHR23147:SF44 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 1 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000005829.1|UniProtKB=W5MF79 W5MF79 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000012608.1|UniProtKB=W5N4G2 W5N4G2 PTHR46152:SF2 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN 2 binding#GO:0005488;protein binding#GO:0005515 intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 LEPOC|Ensembl=ENSLOCG00000012138.1|UniProtKB=W5N2S2 W5N2S2 PTHR22793:SF11 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN muscle tissue development#GO:0060537;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;muscle structure development#GO:0061061;cell differentiation#GO:0030154;circulatory system development#GO:0072359;muscle cell differentiation#GO:0042692;striated muscle cell differentiation#GO:0051146;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;cardiac muscle cell differentiation#GO:0055007;multicellular organismal process#GO:0032501;tissue development#GO:0009888;heart development#GO:0007507;cellular process#GO:0009987 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000001061.1|UniProtKB=W5LYK4 W5LYK4 PTHR10828:SF48 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 M-PHASE INDUCER PHOSPHATASE 2 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of cell cycle G2/M phase transition#GO:1902749;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;regulation of cell cycle#GO:0051726;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic cell cycle phase transition#GO:0044772 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005436.1|UniProtKB=W5MDU1 W5MDU1 PTHR21642:SF2 CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN-LIKE animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;circulatory system development#GO:0072359;heart development#GO:0007507;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887 LEPOC|Ensembl=ENSLOCG00000017263.1|UniProtKB=W5NL43 W5NL43 PTHR13084:SF3 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 2 regulation of biological process#GO:0050789;regulation of transport#GO:0051049;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000008864.1|UniProtKB=W5MQY1 W5MQY1 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000018127.1|UniProtKB=W5NNL9 W5NNL9 PTHR37984:SF27 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000018219.1|UniProtKB=W5NNW1 W5NNW1 PTHR15357:SF2 OLFACTORY MARKER PROTEIN OLFACTORY MARKER PROTEIN cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;neurogenesis#GO:0022008;system development#GO:0048731;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;cell body#GO:0044297;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cytosol#GO:0005829;nucleus#GO:0005634;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000011635.1|UniProtKB=W5N0Y6 W5N0Y6 PTHR14186:SF26 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015767.1|UniProtKB=W5NFK2 W5NFK2 PTHR22625:SF4 PLEXIN PLEXIN-C1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;system development#GO:0048731;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;regulation of axonogenesis#GO:0050770;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;signaling#GO:0023052;synapse assembly#GO:0007416;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of nervous system development#GO:0051962;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;positive regulation of axonogenesis#GO:0050772 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017070.1|UniProtKB=W5NKD8 W5NKD8 PTHR43108:SF5 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-ACETYLGLUCOSAMINE-6-SULFATASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238 lysosome#GO:0005764;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003859.1|UniProtKB=W5M8A0 W5M8A0 PTHR22897:SF7 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE 2 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 extracellular matrix assembly#GO:0085029;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000005259.1|UniProtKB=W5MD74 W5MD74 PTHR24304:SF3 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 7A1 oxidoreductase activity#GO:0016491;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;homeostatic process#GO:0042592 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012205.1|UniProtKB=W5N307 W5N307 PTHR11818:SF107 BETA/GAMMA CRYSTALLIN CRYGMX PROTEIN structural molecule activity#GO:0005198 system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;nervous system process#GO:0050877;sensory perception#GO:0007600;animal gross anatomical part developmental process#GO:0160108;camera-type eye development#GO:0043010;visual system development#GO:0150063;visual perception#GO:0007601;sensory perception of light stimulus#GO:0050953 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008936.1|UniProtKB=W5MR75 W5MR75 PTHR22811:SF117 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193 vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001701.1|UniProtKB=W5M0S6 W5M0S6 PTHR21422:SF18 RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 anatomical structure development#GO:0048856;system development#GO:0048731;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;developmental process#GO:0032502;multicellular organismal process#GO:0032501;brain development#GO:0007420;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;regulation of autophagosome assembly#GO:2000785;positive regulation of cellular component organization#GO:0051130;central nervous system development#GO:0007417;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;positive regulation of macroautophagy#GO:0016239;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of macroautophagy#GO:0016241;positive regulation of cellular component biogenesis#GO:0044089;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of autophagy#GO:0010508;positive regulation of biological process#GO:0048518 G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000016195.1|UniProtKB=W5NH56 W5NH56 EIF3L PTHR13242:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000014364.1|UniProtKB=W5NAM5 W5NAM5 PTHR12219:SF17 NADH-UBIQUINONE OXIDOREDUCTASE WD REPEAT-CONTAINING PROTEIN 93 NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;electron transport chain#GO:0022900;cellular respiration#GO:0045333;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009047.1|UniProtKB=W5MRM6 W5MRM6 PTHR45623:SF7 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD1 nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;DNA binding#GO:0003677;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;histone binding#GO:0042393;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097 protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;nucleosome organization#GO:0034728;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005881.1|UniProtKB=W5MFF0 W5MFF0 PTHR12831:SF0 TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3 nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;response to stimulus#GO:0050896;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;gene expression#GO:0010467 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 LEPOC|Ensembl=ENSLOCG00000004909.1|UniProtKB=W5MBZ1 W5MBZ1 PTHR46985:SF8 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD-RELATED endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;peptidase activator activity#GO:0016504;molecular function regulator activity#GO:0098772;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;defense response#GO:0006952;positive regulation of response to biotic stimulus#GO:0002833;apoptotic signaling pathway#GO:0097190;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stress#GO:0080134;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of defense response#GO:0031347;inflammatory response#GO:0006954;regulation of immune response#GO:0050776;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;positive regulation of response to external stimulus#GO:0032103;signaling#GO:0023052;response to stimulus#GO:0050896;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;immune system process#GO:0002376 cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;canonical inflammasome complex#GO:0061702;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003646.1|UniProtKB=W5M7G8 W5M7G8 PTHR24027:SF433 CADHERIN-23 CADHERIN-LIKE PROTEIN 26-RELATED beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;cell migration#GO:0016477;cell motility#GO:0048870 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 cadherin#PC00057;cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000399.1|UniProtKB=W5LWD0 W5LWD0 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000003706.1|UniProtKB=W5M7P8 W5M7P8 PTHR21472:SF18 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN-LIKE LEPOC|Ensembl=ENSLOCG00000004805.1|UniProtKB=W5MBL0 W5MBL0 PTHR10245:SF15 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 LEPOC|Ensembl=ENSLOCG00000003283.1|UniProtKB=W5M690 W5M690 PTHR10027:SF14 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;outward rectifier potassium channel activity#GO:0015271;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012524.1|UniProtKB=W5N464 W5N464 PTHR10740:SF17 TRANSFORMING GROWTH FACTOR ALPHA PROHEPARIN-BINDING EGF-LIKE GROWTH FACTOR receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;positive regulation of organelle organization#GO:0010638;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cellular component organization#GO:0051130;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of nuclear division#GO:0051783;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of mitotic cell cycle#GO:0007346;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;regulation of mitotic nuclear division#GO:0007088;cell surface receptor signaling pathway#GO:0007166;positive regulation of mitotic nuclear division#GO:0045840 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000011122.1|UniProtKB=W5MZ55 W5MZ55 PTHR14700:SF0 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, MITOCHONDRIAL PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, MITOCHONDRIAL regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;regulation of RNA metabolic process#GO:0051252 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003049.1|UniProtKB=W5M5I1 W5M5I1 PTHR11731:SF208 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED INACTIVE DIPEPTIDYL PEPTIDASE 10-LIKE ISOFORM X1 peptidase activity#GO:0008233;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459 proteolysis#GO:0006508;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;regulation of metal ion transport#GO:0010959;regulation of cellular process#GO:0050794;regulation of monoatomic cation transmembrane transport#GO:1904062;metabolic process#GO:0008152;regulation of transport#GO:0051049;regulation of localization#GO:0032879;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;biological regulation#GO:0065007;regulation of monoatomic ion transport#GO:0043269 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000000097.1|UniProtKB=W5LVF4 W5LVF4 PTHR14140:SF2 E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED E3 UBIQUITIN-PROTEIN LIGASE UHRF1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 post-translational protein modification#GO:0043687;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein ubiquitination#GO:0016567;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016895.1|UniProtKB=W5NJS9 W5NJS9 PTHR24020:SF17 COLLAGEN ALPHA COLLAGEN ALPHA-1(XII) CHAIN cell differentiation#GO:0030154;gastrulation#GO:0007369;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;formation of primary germ layer#GO:0001704;multicellular organismal process#GO:0032501;tissue development#GO:0009888;endoderm formation#GO:0001706;embryo development#GO:0009790;cellular process#GO:0009987;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular developmental process#GO:0048869;anatomical structure formation involved in morphogenesis#GO:0048646;endoderm development#GO:0007492;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863 LEPOC|Ensembl=ENSLOCG00000015182.1|UniProtKB=W5NDH5 W5NDH5 PTHR46051:SF8 SH2 DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 5-PHOSPHATASE 2B catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015037.1|UniProtKB=W5NCZ7 W5NCZ7 PTHR16015:SF0 TRANSMEMBRANE PROTEIN 51 TRANSMEMBRANE PROTEIN 51 LEPOC|Ensembl=ENSLOCG00000005081.1|UniProtKB=W5MCL2 W5MCL2 PTHR12191:SF14 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP10 active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;transition metal ion transmembrane transporter activity#GO:0046915 monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000000711.1|UniProtKB=W5LXD1 W5LXD1 PTHR23266:SF388 IMMUNOGLOBULIN HEAVY CHAIN IG HEAVY CHAIN V REGION 345-RELATED antigen binding#GO:0003823;binding#GO:0005488 adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;immune effector process#GO:0002252;immune system process#GO:0002376 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007676.1|UniProtKB=W5MLS5 W5MLS5 PTHR45965:SF4 INACTIVE RHOMBOID PROTEIN INACTIVE RHOMBOID PROTEIN 1 regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;regulation of secretion by cell#GO:1903530;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of secretion#GO:0051046;regulation of signaling#GO:0023051 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000005111.1|UniProtKB=W5MCP5 W5MCP5 PTHR12002:SF92 CLAUDIN CLAUDIN-1 binding#GO:0005488;protein binding#GO:0005515;virus receptor activity#GO:0001618 cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;cell adhesion#GO:0007155 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical junction complex#GO:0043296;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161 cell junction protein#PC00070;tight junction#PC00214 LEPOC|Ensembl=ENSLOCG00000005102.1|UniProtKB=W5MCN4 W5MCN4 PTHR11848:SF320 TGF-BETA FAMILY NODAL-RELATED 1-RELATED signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000010560.1|UniProtKB=W5MX29 W5MX29 PTHR46098:SF1 TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a tRNA#GO:0140101 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000004818.1|UniProtKB=W5MBP6 W5MBP6 DRAXIN PTHR28610:SF1 DRAXIN DRAXIN animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;negative regulation of signal transduction#GO:0009968;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;head development#GO:0060322;regulation of canonical Wnt signaling pathway#GO:0060828;neuron projection development#GO:0031175;cellular process#GO:0009987;negative regulation of cell communication#GO:0010648;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;forebrain development#GO:0030900;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;central nervous system development#GO:0007417;cell development#GO:0048468;regulation of Wnt signaling pathway#GO:0030111;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;neuron projection morphogenesis#GO:0048812;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;negative regulation of Wnt signaling pathway#GO:0030178;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;brain development#GO:0007420;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;axon development#GO:0061564;axon guidance#GO:0007411;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013224.1|UniProtKB=W5N6N1 W5N6N1 PTHR11241:SF0 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;nucleoside triphosphate diphosphatase activity#GO:0047429;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;nucleoside monophosphate biosynthetic process#GO:0009124;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide catabolic process#GO:0009166;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086 phosphatase#PC00181;hydrolase#PC00121 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUTP pyrophosphatase#P02918 LEPOC|Ensembl=ENSLOCG00000005461.1|UniProtKB=W5MDX5 W5MDX5 PTHR15933:SF1 PROTEIN CBG16327 F-BOX ONLY PROTEIN 40 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015318.1|UniProtKB=W5NDZ0 W5NDZ0 PTHR12570:SF10 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED MGC108429 PROTEIN magnesium ion transport#GO:0015693;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000008354.1|UniProtKB=W5MP82 W5MP82 PTHR13743:SF62 BEIGE/BEACH-RELATED NEUROBEACHIN protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011636.1|UniProtKB=W5N0Z8 W5N0Z8 PTHR11362:SF133 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML38 membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000004128.1|UniProtKB=W5M996 W5M996 PTHR24073:SF555 DRAB5-RELATED RAS-RELATED PROTEIN RAB-5B ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 endocytosis#GO:0006897;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000014194.1|UniProtKB=W5NA32 W5NA32 PTHR18861:SF3 ELKS/RAB6-INTERACTING/CAST PROTEIN ERC PROTEIN 2 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cytoplasm#GO:0005737;cell cortex#GO:0005938;presynapse#GO:0098793;cell periphery#GO:0071944;cell junction#GO:0030054;presynaptic active zone#GO:0048786;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003079.1|UniProtKB=W5M5I9 W5M5I9 PTHR11254:SF396 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE E3 UBIQUITIN-PROTEIN LIGASE WWP2 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of monoatomic ion transport#GO:0043269;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 LEPOC|Ensembl=ENSLOCG00000000653.1|UniProtKB=W5LX64 W5LX64 PTHR23104:SF15 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN CELL GROWTH REGULATOR WITH EF HAND DOMAIN PROTEIN 1 negative regulation of biological process#GO:0048519;regulation of growth#GO:0040008;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cell growth#GO:0001558;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell growth#GO:0030308;negative regulation of cellular process#GO:0048523 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011381.1|UniProtKB=W5N051 W5N051 PTHR22948:SF18 TUDOR DOMAIN CONTAINING PROTEIN TUDOR AND KH DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008470.1|UniProtKB=W5MPK6 W5MPK6 PTHR43173:SF28 ABC1 FAMILY PROTEIN AARF DOMAIN CONTAINING KINASE 5 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000009149.1|UniProtKB=W5MRZ7 W5MRZ7 PTHR10194:SF52 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN NGAP GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 LEPOC|Ensembl=ENSLOCG00000014920.1|UniProtKB=W5NCL3 W5NCL3 PTHR43243:SF20 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 3 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;amino acid transport#GO:0006865;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 amino acid transporter#PC00046;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000010200.1|UniProtKB=W5MVT1 W5MVT1 PTHR31655:SF0 PROTEIN FAM78A PROTEIN FAM78B LEPOC|Ensembl=ENSLOCG00000013444.1|UniProtKB=W5N7G5 W5N7G5 PTHR10370:SF0 ERYTHROPOIETIN ERYTHROPOIETIN hormone activity#GO:0005179;signaling receptor binding#GO:0005102;kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;protein kinase activator activity#GO:0030295;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;protein kinase regulator activity#GO:0019887;signaling receptor activator activity#GO:0030546;kinase regulator activity#GO:0019207;enzyme activator activity#GO:0008047 cytokine-mediated signaling pathway#GO:0019221;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872;cell communication#GO:0007154;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;response to peptide#GO:1901652;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052;cell development#GO:0048468;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;response to cytokine#GO:0034097;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;hemopoiesis#GO:0030097;cell surface receptor signaling pathway via STAT#GO:0097696 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000003064.1|UniProtKB=W5M5E8 W5M5E8 PTHR42919:SF8 N-ALPHA-ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 50 N-acetyltransferase activity#GO:0008080;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic sister chromatid cohesion#GO:0007064 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248 acetyltransferase#PC00038;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000014062.1|UniProtKB=W5N9L9 W5N9L9 PTHR24330:SF12 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN BARH-LIKE 1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000017325.1|UniProtKB=W5NLC1 W5NLC1 PTHR13445:SF3 TUMOR SUPPRESSING SUBTRANSFERABLE CANDIDATE 4 TSSC4 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN TSSC4 mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013134.1|UniProtKB=W5N6C1 W5N6C1 PTHR10460:SF60 ABL INTERACTOR FAMILY MEMBER ABI GENE FAMILY MEMBER 3 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron migration#GO:0001764;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell migration#GO:0016477;nervous system development#GO:0007399 cell leading edge#GO:0031252;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;lamellipodium#GO:0030027;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011089.1|UniProtKB=W5MZ12 W5MZ12 PTHR34340:SF3 MELANOREGULIN MELANOREGULIN developmental pigmentation#GO:0048066;cellular process#GO:0009987;melanocyte differentiation#GO:0030318;vesicle localization#GO:0051648;establishment of localization in cell#GO:0051649;cellular pigmentation#GO:0033059;establishment of vesicle localization#GO:0051650;transport#GO:0006810;developmental process#GO:0032502;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;establishment of organelle localization#GO:0051656;cell differentiation#GO:0030154;organelle localization#GO:0051640;pigmentation#GO:0043473;cellular localization#GO:0051641;localization#GO:0051179 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;melanosome#GO:0042470;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000009097.1|UniProtKB=W5MRT6 W5MRT6 PTHR10921:SF2 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;protein-containing complex organization#GO:0043933;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;organelle transport along microtubule#GO:0072384;chromosome localization#GO:0050000;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;spindle localization#GO:0051653;cellular localization#GO:0051641;establishment or maintenance of cell polarity#GO:0007163;nuclear division#GO:0000280;microtubule-based transport#GO:0099111;establishment of organelle localization#GO:0051656;centrosome localization#GO:0051642;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;transport along microtubule#GO:0010970;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;vesicle cytoskeletal trafficking#GO:0099518;microtubule polymerization#GO:0046785;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;cell migration#GO:0016477;microtubule polymerization or depolymerization#GO:0031109;establishment of spindle localization#GO:0051293;vesicle localization#GO:0051648;localization#GO:0051179;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;organelle localization#GO:0051640;mitotic cell cycle#GO:0000278;cell motility#GO:0048870;microtubule-based movement#GO:0007018;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;establishment of cell polarity#GO:0030010 chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;kinetochore#GO:0000776;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;microtubule organizing center#GO:0005815;centrosome#GO:0005813;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000009828.1|UniProtKB=W5MUF7 W5MUF7 PTHR24064:SF198 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000003639.1|UniProtKB=W5M7G3 W5M7G3 AK5 PTHR23359:SF79 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 5 phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740 ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nucleoside diphosphate metabolic process#GO:0009132;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 LEPOC|Ensembl=ENSLOCG00000004157.1|UniProtKB=W5M9B3 W5M9B3 PTHR14969:SF14 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 dephosphorylation#GO:0016311;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;alcohol metabolic process#GO:0006066;small molecule metabolic process#GO:0044281;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010736.1|UniProtKB=W5MXP4 W5MXP4 PTHR48033:SF2 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D-LIKE nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003537.1|UniProtKB=W5M727 W5M727 PTHR10836:SF79 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, TESTIS-SPECIFIC oxidoreductase activity#GO:0016491;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810 LEPOC|Ensembl=ENSLOCG00000000641.1|UniProtKB=W5LX56 W5LX56 PTHR46117:SF1 FI24210P1 UPSTREAM STIMULATORY FACTOR 1 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000014534.1|UniProtKB=W5NB77 W5NB77 PTHR11003:SF28 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 6 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000014354.1|UniProtKB=W5NAM0 W5NAM0 PTHR11616:SF126 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294 amino acid transport#GO:0006865;transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000006648.1|UniProtKB=W5MI32 W5MI32 PTHR12093:SF11 NCK-ASSOCIATED PROTEIN 1 NCK-ASSOCIATED PROTEIN 1 neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;cell migration#GO:0016477;multicellular organismal process#GO:0032501;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;system development#GO:0048731;anatomical structure development#GO:0048856;cortical actin cytoskeleton organization#GO:0030866;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;organelle organization#GO:0006996;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000013687.1|UniProtKB=W5N8B4 W5N8B4 PTHR45740:SF7 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE TIPARP glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000017850.1|UniProtKB=W5NMU4 W5NMU4 PTHR10903:SF180 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7-LIKE ISOFORM X1 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000002586.1|UniProtKB=W5M3V3 W5M3V3 PTHR46513:SF16 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 5 system development#GO:0048731;nervous system development#GO:0007399;multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Wnt signaling pathway#P00057>LRP5/6#P01431 LEPOC|Ensembl=ENSLOCG00000013353.1|UniProtKB=W5N7A3 W5N7A3 PTHR15036:SF33 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 2 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;cognition#GO:0050890;animal gross anatomical part developmental process#GO:0160108;nervous system process#GO:0050877;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502 membrane#GO:0016020;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001409.1|UniProtKB=W5LZQ6 W5LZQ6 PTHR46259:SF1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000016888.1|UniProtKB=W5NJS5 W5NJS5 PTHR11164:SF0 GLUTAMATE CYSTEINE LIGASE GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 peptide metabolic process#GO:0006518;biosynthetic process#GO:0009058;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 ligase#PC00142;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014989.1|UniProtKB=W5NCU4 W5NCU4 PTHR10962:SF7 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2A binding#GO:0005488;peptide binding#GO:0042277 negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010482.1|UniProtKB=W5MWX6 W5MWX6 PTHR11908:SF129 XANTHINE DEHYDROGENASE XANTHINE DEHYDROGENASE_OXIDASE oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006439.1|UniProtKB=W5MHC8 W5MHC8 PTHR11566:SF225 DYNAMIN INTERFERON-INDUCED GTP-BINDING PROTEIN MX-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;hydrolase activity#GO:0016787;protein binding#GO:0005515;GTPase activity#GO:0003924;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 cellular localization#GO:0051641;cellular component organization#GO:0016043;defense response to virus#GO:0051607;establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;response to stress#GO:0006950;synaptic vesicle transport#GO:0048489;organelle organization#GO:0006996;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;organelle localization#GO:0051640;response to virus#GO:0009615;localization#GO:0051179;synaptic vesicle endocytosis#GO:0048488;response to external biotic stimulus#GO:0043207;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;defense response#GO:0006952;response to external stimulus#GO:0009605;vesicle localization#GO:0051648;synaptic vesicle recycling#GO:0036465;response to other organism#GO:0051707;membrane organization#GO:0061024 intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cell junction#GO:0030054;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000015796.1|UniProtKB=W5NFP2 W5NFP2 PTHR47958:SF26 ATP-DEPENDENT RNA HELICASE DBP3 EUKARYOTIC INITIATION FACTOR 4A-III binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000013556.1|UniProtKB=W5N7V4 W5N7V4 PTHR11675:SF129 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE-LIKE 6 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009980.1|UniProtKB=W5MUZ5 W5MUZ5 PTHR12920:SF3 RYBP AND YAF2-RELATED RING1 AND YY1-BINDING PROTEIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011839.1|UniProtKB=W5N1Q0 W5N1Q0 PTHR12589:SF10 PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE 6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000000579.1|UniProtKB=W5LWY4 W5LWY4 PTHR12434:SF6 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000015475.1|UniProtKB=W5NEI5 W5NEI5 PTHR47979:SF73 DRAB11-RELATED RAS-RELATED PROTEIN RAB-4A guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 transport#GO:0006810;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;regulation of biological process#GO:0050789;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128 secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000003172.1|UniProtKB=W5M5U3 W5M5U3 PTHR15301:SF10 INSULIN-INDUCED GENE 1 INSULIN-INDUCED GENE 2 PROTEIN secondary alcohol biosynthetic process#GO:1902653;negative regulation of cellular process#GO:0048523;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;cholesterol metabolic process#GO:0008203;lipid biosynthetic process#GO:0008610;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to peptide hormone#GO:0043434;SREBP signaling pathway#GO:0032933;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;alcohol metabolic process#GO:0006066;cholesterol biosynthetic process#GO:0006695;cellular response to lipid#GO:0071396;negative regulation of signal transduction#GO:0009968;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;cellular localization#GO:0051641;negative regulation of cell communication#GO:0010648;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;secondary alcohol metabolic process#GO:1902652;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;intracellular protein localization#GO:0008104;regulation of response to stress#GO:0080134;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cellular response to nitrogen compound#GO:1901699;regulation of signal transduction#GO:0009966;macromolecule localization#GO:0033036;cell communication#GO:0007154;localization#GO:0051179;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cellular response to peptide hormone stimulus#GO:0071375;metabolic process#GO:0008152;response to chemical#GO:0042221;response to lipid#GO:0033993;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;response to hormone#GO:0009725;response to stress#GO:0006950;negative regulation of intracellular signal transduction#GO:1902532;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719 membrane protein complex#GO:0098796;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000005411.1|UniProtKB=W5MDS3 W5MDS3 PTHR10288:SF234 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 3 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009962.1|UniProtKB=W5MUX4 W5MUX4 PTHR10196:SF57 SUGAR KINASE XYLULOSE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200;phosphotransferase activity, alcohol group as acceptor#GO:0016773 carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 carbohydrate kinase#PC00065;kinase#PC00137 Ascorbate degradation#P02729>L-xylulose kinase#P02849 LEPOC|Ensembl=ENSLOCG00000013198.1|UniProtKB=W5N6K7 W5N6K7 PTHR33862:SF3 OROFACIAL CLEFT 1 CANDIDATE GENE 1 PROTEIN OROFACIAL CLEFT 1 CANDIDATE 1 LEPOC|Ensembl=ENSLOCG00000016392.1|UniProtKB=W5NHY6 W5NHY6 PTHR46808:SF1 H2.0-LIKE HOMEOBOX PROTEIN H2.0-LIKE HOMEOBOX PROTEIN sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000015733.1|UniProtKB=W5NFG2 W5NFG2 PTHR11223:SF3 EXPORTIN 1/5 EXPORTIN-5 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 establishment of localization#GO:0051234;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004293.1|UniProtKB=W5M9S2 W5M9S2 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;signaling receptor activity#GO:0038023;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018082.1|UniProtKB=W5NNH4 W5NNH4 PTHR11214:SF410 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 6 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194 glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000005494.1|UniProtKB=W5ME25 W5ME25 PTHR24125:SF1 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1B LEPOC|Ensembl=ENSLOCG00000018305.1|UniProtKB=W5NP47 W5NP47 PTHR13936:SF2 PROFILIN PROFILIN-3 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;positive regulation of actin filament bundle assembly#GO:0032233;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament polymerization#GO:0030833;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 LEPOC|Ensembl=ENSLOCG00000010853.1|UniProtKB=W5MY43 W5MY43 PTHR28546:SF2 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2 biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;regulation of biological quality#GO:0065008;protein transport#GO:0015031;localization#GO:0051179;macromolecule metabolic process#GO:0043170;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072 endosome#GO:0005768;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;postsynapse#GO:0098794;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;glutamatergic synapse#GO:0098978;endomembrane system#GO:0012505;late endosome#GO:0005770;plasma membrane region#GO:0098590 LEPOC|Ensembl=ENSLOCG00000016231.1|UniProtKB=W5NHA5 W5NHA5 PTHR19282:SF455 TETRASPANIN TETRASPANIN-16 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015023.1|UniProtKB=W5NCY4 W5NCY4 PTHR12901:SF14 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG, MITOCHONDRIAL intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000004070.1|UniProtKB=W5M8Z8 W5M8Z8 PTHR31395:SF30 SHISA PROTEIN SHISA-2 HOMOLOG ISOFORM X1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003319.1|UniProtKB=W5M6E1 W5M6E1 PTHR13817:SF85 TITIN DCC NETRIN 1 RECEPTOR structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014230.1|UniProtKB=W5NA66 W5NA66 PTHR15453:SF8 TUMOR SUPPRESSOR CANDIDATE 2 TUMOR SUPPRESSOR CANDIDATE 2 response to stress#GO:0006950;inflammatory response#GO:0006954;response to stimulus#GO:0050896;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;defense response#GO:0006952 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000003071.1|UniProtKB=W5M5F4 W5M5F4 PTHR45718:SF3 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLIS1 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000000786.1|UniProtKB=W5LXL9 W5LXL9 PTHR10554:SF6 SYNTROPHIN ALPHA-1-SYNTROPHIN molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 circulatory system process#GO:0003013;cardiac muscle contraction#GO:0060048;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;muscle system process#GO:0003012;action potential#GO:0001508;heart process#GO:0003015;actin-mediated cell contraction#GO:0070252;striated muscle contraction#GO:0006941;muscle contraction#GO:0006936;cardiac muscle cell contraction#GO:0086003;regulation of membrane potential#GO:0042391;heart contraction#GO:0060047;system process#GO:0003008;actin filament-based movement#GO:0030048;cellular process#GO:0009987;blood circulation#GO:0008015;cardiac muscle cell action potential involved in contraction#GO:0086002;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;cell junction#GO:0030054;sarcolemma#GO:0042383;neuromuscular junction#GO:0031594 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014552.1|UniProtKB=W5NBA4 W5NBA4 PTHR13556:SF2 TRANSCRIPTIONAL ADAPTER 3-RELATED TRANSCRIPTIONAL ADAPTER 3 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000002550.1|UniProtKB=W5M3Q3 W5M3Q3 PTHR21258:SF45 DOCKING PROTEIN RELATED DOCKING PROTEIN 5 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014436.1|UniProtKB=W5NAW5 W5NAW5 PTHR11036:SF28 SEMAPHORIN SEMA DOMAIN, IMMUNOGLOBULIN DOMAIN (IG), SHORT BASIC DOMAIN, SECRETED, (SEMAPHORIN) 3GA signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;taxis#GO:0042330;response to chemical#GO:0042221;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;response to external stimulus#GO:0009605;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon guidance#GO:0007411;axon development#GO:0061564 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000013273.1|UniProtKB=W5N6W9 W5N6W9 PTHR13950:SF13 RABCONNECTIN-RELATED DMX-LIKE PROTEIN 2 transport#GO:0006810;intracellular transport#GO:0046907;regulation of monoatomic cation transmembrane transport#GO:1904062;protein-containing complex organization#GO:0043933;regulation of transport#GO:0051049;regulation of localization#GO:0032879;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of monoatomic ion transmembrane transport#GO:0034765;early endosome to late endosome transport#GO:0045022;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;regulation of monoatomic ion transport#GO:0043269;cellular component assembly#GO:0022607;cellular localization#GO:0051641;localization#GO:0051179;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of transmembrane transport#GO:0034762;cellular component organization#GO:0016043;regulation of cellular process#GO:0050794 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cell junction#GO:0030054;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle#GO:0030133;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793 LEPOC|Ensembl=ENSLOCG00000011795.1|UniProtKB=W5N1K6 W5N1K6 PTHR14650:SF1 PROLYL HYDROXYLASE-RELATED 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 3 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001812.1|UniProtKB=W5M139 W5M139 PTHR31937:SF2 TRANSMEMBRANE PROTEIN 163 TRANSMEMBRANE PROTEIN 163 cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;zinc ion binding#GO:0008270 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;presynapse#GO:0098793;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000001380.1|UniProtKB=W5LZP8 W5LZP8 PTHR24103:SF672 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN_ISG15 LIGASE TRIM25-LIKE ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004270.1|UniProtKB=W5M9P6 W5M9P6 PTHR19370:SF108 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE 2 catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on NAD(P)H#GO:0016651 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009420.1|UniProtKB=W5MSY5 W5MSY5 PTHR10024:SF114 SYNAPTOTAGMIN SYNAPTOTAGMIN-4 molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149 regulation of cellular component organization#GO:0051128;signaling#GO:0023052;export from cell#GO:0140352;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;positive regulation of cellular component organization#GO:0051130;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;synaptic vesicle exocytosis#GO:0016079;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;regulation of localization#GO:0032879;exocytosis#GO:0006887;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;regulated exocytosis#GO:0045055;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;vesicle fusion#GO:0006906;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;biological regulation#GO:0065007;membrane fusion#GO:0061025;positive regulation of cellular process#GO:0048522;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810 cell junction#GO:0030054;secretory vesicle#GO:0099503;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;axon#GO:0030424;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025 membrane trafficking regulatory protein#PC00151 Gonadotropin-releasing hormone receptor pathway#P06664>Syt IV#P06746 LEPOC|Ensembl=ENSLOCG00000002324.1|UniProtKB=W5M2W8 W5M2W8 PTHR16209:SF5 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 WW DOMAIN-BINDING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000001987.1|UniProtKB=W5M1Q1 W5M1Q1 PTHR24271:SF102 KALLIKREIN-RELATED KALLIKREIN 1 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000003385.1|UniProtKB=W5M6J8 W5M6J8 PTHR13107:SF0 N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT N(6)-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT METTL14 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;RNA modification#GO:0009451;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;mRNA modification#GO:0016556;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071 nucleus#GO:0005634;methyltransferase complex#GO:0034708;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000012036.1|UniProtKB=W5N2F0 W5N2F0 PTHR46900:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488;phosphatidylinositol 3-kinase binding#GO:0043548 regulation of synapse organization#GO:0050807;regulation of signaling#GO:0023051;regulation of cell junction assembly#GO:1901888;regulation of intracellular signal transduction#GO:1902531;regulation of biological quality#GO:0065008;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;negative regulation of multicellular organismal process#GO:0051241;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of multicellular organismal process#GO:0051239;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of synapse assembly#GO:0051963 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000007307.1|UniProtKB=W5MKE5 W5MKE5 PTHR45711:SF2 CHLORIDE CHANNEL PROTEIN H(+)_CL(-) EXCHANGE TRANSPORTER 4 passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821 intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000011485.1|UniProtKB=W5N0I0 W5N0I0 PTHR11905:SF114 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 11 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000014029.1|UniProtKB=W5N9I4 W5N9I4 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 binding#GO:0005488;chromatin binding#GO:0003682 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000009625.1|UniProtKB=W5MTQ2 W5MTQ2 PTHR12970:SF1 PROTEASOME ASSEMBLY CHAPERONE 2 PROTEASOME ASSEMBLY CHAPERONE 2 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002136.1|UniProtKB=W5M289 W5M289 PTHR10918:SF4 HOMER HOMER PROTEIN HOMOLOG 3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 regulation of monoatomic ion transport#GO:0043269;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of localization#GO:0032879;regulation of transport#GO:0051049;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of metal ion transport#GO:0010959;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186 dendrite#GO:0030425;postsynaptic density#GO:0014069;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000010656.1|UniProtKB=W5MXF5 W5MXF5 PTHR13487:SF3 SERINE PROTEASE INHIBITOR REVERSION-INDUCING CYSTEINE-RICH PROTEIN WITH KAZAL MOTIFS endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;circulatory system development#GO:0072359;regulation of Wnt signaling pathway#GO:0030111;blood vessel morphogenesis#GO:0048514;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;angiogenesis#GO:0001525;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;sprouting angiogenesis#GO:0002040;regulation of signaling#GO:0023051;multicellular organismal process#GO:0032501;developmental maturation#GO:0021700;tube development#GO:0035295;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure maturation#GO:0071695;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;external encapsulating structure organization#GO:0045229;system development#GO:0048731 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000003842.1|UniProtKB=W5M886 W5M886 PTHR43557:SF8 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;programmed cell death#GO:0012501 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000004845.1|UniProtKB=W5MBR5 W5MBR5 PTHR14690:SF11 IQ MOTIF CONTAINING WITH AAA DOMAIN 1 DYNEIN REGULATORY COMPLEX PROTEIN 11 ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000008785.1|UniProtKB=W5MQN5 W5MQN5 PTHR22802:SF444 C-TYPE LECTIN SUPERFAMILY MEMBER SI:CH211-125E6.12 PROTEIN binding#GO:0005488;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011935.1|UniProtKB=W5N223 W5N223 PTHR12223:SF28 VESICULAR MANNOSE-BINDING LECTIN LECTIN, MANNOSE BINDING 1 LIKE carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029;binding#GO:0005488;small molecule binding#GO:0036094 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000018294.1|UniProtKB=W5NP36 W5NP36 PTHR22750:SF17 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 2 bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008100.1|UniProtKB=W5MN80 W5MN80 PTHR13793:SF27 PHD FINGER PROTEINS PROTEIN JADE-3 histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;chromatin-protein adaptor activity#GO:0140463 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000005660.1|UniProtKB=W5MEM7 W5MEM7 PTHR17616:SF13 YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER TRANSCRIPTIONAL COACTIVATOR YAP1 transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;hippo signaling#GO:0035329;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000015513.1|UniProtKB=W5NEN3 W5NEN3 PTHR12019:SF5 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN EMERIN (EMERY-DREIFUSS MUSCULAR DYSTROPHY) intercellular signal molecule#PC00207;peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000004354.1|UniProtKB=W5M9Z9 W5M9Z9 PTHR19302:SF13 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 reproductive process#GO:0022414;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000012728.1|UniProtKB=W5N4V4 W5N4V4 PTHR19282:SF63 TETRASPANIN TETRASPANIN-5 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004421.1|UniProtKB=W5MA77 W5MA77 PTHR10048:SF33 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA ISOFORM kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886 kinase#PC00137 Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;Ras Pathway#P04393>PI3K#P04567;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Interleukin signaling pathway#P00036>PI3K#P00990;p53 pathway feedback loops 2#P04398>PI3K#P04661;Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557;FGF signaling pathway#P00021>PI3K#P00640;B cell activation#P00010>PI3K#P00391;CCKR signaling map#P06959>p110#P07020;T cell activation#P00053>PI3K#P01322;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;PI3 kinase pathway#P00048>P110ACT#P01177;VEGF signaling pathway#P00056>PI3K#P01413;PI3 kinase pathway#P00048>p110#P01192 LEPOC|Ensembl=ENSLOCG00000005771.1|UniProtKB=W5MF19 W5MF19 PTHR13578:SF19 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL1 chromatin binding#GO:0003682;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of RNA metabolic process#GO:0051254;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557 PcG protein complex#GO:0031519;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000006818.1|UniProtKB=W5MIQ1 W5MIQ1 PTHR24082:SF112 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 2 transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 cellular response to chemical stimulus#GO:0070887;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;hormone-mediated signaling pathway#GO:0009755;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;negative regulation of macromolecule biosynthetic process#GO:0010558;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000017921.1|UniProtKB=W5NN15 W5NN15 PTHR11537:SF296 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 3 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249 regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;potassium ion transport#GO:0006813;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;metal ion transport#GO:0030001;action potential#GO:0001508 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000001447.1|UniProtKB=W5LZU0 W5LZU0 PTHR43758:SF2 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE OXIDIZED PURINE NUCLEOSIDE TRIPHOSPHATE HYDROLASE nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462 cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000011052.1|UniProtKB=W5MYW8 W5MYW8 PTHR19853:SF0 WD REPEAT CONTAINING PROTEIN 3 WDR3 WD REPEAT-CONTAINING PROTEIN 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000008980.1|UniProtKB=W5MRD3 W5MRD3 PTHR24099:SF18 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM36 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;sexual reproduction#GO:0019953;reproductive process#GO:0022414;fertilization#GO:0009566;cytoskeleton organization#GO:0007010;cell cycle process#GO:0022402;cellular process#GO:0009987;acrosome reaction#GO:0007340;single fertilization#GO:0007338;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996 acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001984.1|UniProtKB=W5M1P5 W5M1P5 PTHR15175:SF3 NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2 NEUTROPHIL CYTOSOL FACTOR 2 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;superoxide metabolic process#GO:0006801 oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;catalytic complex#GO:1902494 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006796.1|UniProtKB=W5MIK5 W5MIK5 PTHR24025:SF1 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-2 calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000006932.1|UniProtKB=W5MJ34 W5MJ34 PTHR11567:SF202 ACID PHOSPHATASE-RELATED LYSOPHOSPHATIDIC ACID PHOSPHATASE TYPE 6 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000013450.1|UniProtKB=W5N7H3 W5N7H3 PTHR47977:SF20 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-27A ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of localization#GO:0032879;regulation of transport#GO:0051049;exocytosis#GO:0006887;transport#GO:0006810;regulation of cellular process#GO:0050794;export from cell#GO:0140352;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of secretion#GO:0051046;localization#GO:0051179;secretion#GO:0046903;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;positive regulation of secretion#GO:0051047 endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;melanosome#GO:0042470;plasma membrane#GO:0005886;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;Golgi apparatus#GO:0005794;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;apical plasma membrane#GO:0016324;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000004777.1|UniProtKB=W5MBH1 W5MBH1 PTHR46289:SF2 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED THAP-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000006925.1|UniProtKB=W5MJ17 W5MJ17 PTHR10125:SF13 P2X PURINOCEPTOR P2X PURINOCEPTOR 7 passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;monoatomic ion transport#GO:0006811;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;metal ion transport#GO:0030001;signaling#GO:0023052;calcium ion transmembrane transport#GO:0070588;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000015258.1|UniProtKB=W5NDR7 W5NDR7 PTHR12619:SF35 RFX TRANSCRIPTION FACTOR FAMILY TRANSCRIPTION FACTOR RFX4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000014538.1|UniProtKB=W5NB84 W5NB84 PTHR24359:SF34 SERINE/THREONINE-PROTEIN KINASE SBK1 SERINE_THREONINE-PROTEIN KINASE SBK2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000016402.1|UniProtKB=W5NHZ5 W5NHZ5 RNF8 PTHR15067:SF9 E3 UBIQUITIN-PROTEIN LIGASE RNF8 E3 UBIQUITIN-PROTEIN LIGASE RNF8 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;histone binding#GO:0042393;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein modification by small protein conjugation or removal#GO:0070647;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein K48-linked ubiquitination#GO:0070936;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;double-strand break repair#GO:0006302 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000005452.1|UniProtKB=W5MDW9 W5MDW9 PTHR46150:SF1 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN SYDE2 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of Ras protein signal transduction#GO:0046578;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular process#GO:0009987 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000003941.1|UniProtKB=W5M8N7 W5M8N7 PTHR10190:SF11 EYES ABSENT PROTEIN PHOSPHATASE EYA1 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 biological regulation#GO:0065007;positive regulation of DNA repair#GO:0045739;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;inner ear development#GO:0048839;regulation of metabolic process#GO:0019222;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;sensory organ development#GO:0007423;regulation of response to stress#GO:0080134;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;positive regulation of DNA metabolic process#GO:0051054;anatomical structure development#GO:0048856;embryonic organ development#GO:0048568;embryo development#GO:0009790;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;inner ear morphogenesis#GO:0042472;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell differentiation#GO:0030154;sensory organ morphogenesis#GO:0090596;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of cellular response to stress#GO:0080135;ear development#GO:0043583;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000010490.1|UniProtKB=W5MWU8 W5MWU8 PTHR45752:SF156 LEUCINE-RICH REPEAT-CONTAINING RAS SUPPRESSOR PROTEIN 1 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008157.1|UniProtKB=W5MNE8 W5MNE8 PTHR11945:SF804 MADS BOX PROTEIN MYOCYTE ENHANCER FACTOR 2D MEF2D protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;histone deacetylase binding#GO:0042826;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;heart development#GO:0007507;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 MADS box transcription factor#PC00250 LEPOC|Ensembl=ENSLOCG00000002840.1|UniProtKB=W5M4N1 W5M4N1 PTHR11730:SF48 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER AMTB-LIKE DOMAIN-CONTAINING PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 homeostatic process#GO:0042592;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000010750.1|UniProtKB=W5MXR0 W5MXR0 PTHR23426:SF75 FERREDOXIN/ADRENODOXIN ADRENODOXIN, MITOCHONDRIAL electron transport chain#GO:0022900;metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013951.1|UniProtKB=W5N987 W5N987 PTHR11844:SF26 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 4 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of catabolic process#GO:0009895;response to peptide#GO:1901652;regulation of protein catabolic process#GO:0042176;response to chemical#GO:0042221;response to cytokine#GO:0034097;negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;response to hormone#GO:0009725;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003574.1|UniProtKB=W5M777 W5M777 PTHR10036:SF7 CD59 GLYCOPROTEIN LY6_PLAUR DOMAIN-CONTAINING PROTEIN 1 signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;neurotransmitter receptor regulator activity#GO:0099602;acetylcholine receptor inhibitor activity#GO:0030550;signaling receptor regulator activity#GO:0030545;acetylcholine receptor regulator activity#GO:0030548 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;response to chemical#GO:0042221;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699 LEPOC|Ensembl=ENSLOCG00000012451.1|UniProtKB=W5N3W8 W5N3W8 PTHR44229:SF5 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000007068.1|UniProtKB=W5MJJ7 W5MJJ7 PTHR13924:SF4 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 3 cell cycle process#GO:0022402;nuclear migration#GO:0007097;cellular component organization#GO:0016043;cell cycle#GO:0007049;cytoplasmic microtubule organization#GO:0031122;establishment of organelle localization#GO:0051656;cell differentiation#GO:0030154;organelle localization#GO:0051640;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;anatomical structure development#GO:0048856;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;spindle organization#GO:0007051 cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000008492.1|UniProtKB=W5MPM6 W5MPM6 PTHR11214:SF361 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000015880.1|UniProtKB=W5NG04 W5NG04 PTHR24416:SF573 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE 7 catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;protein kinase activity#GO:0004672 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000015400.1|UniProtKB=W5NE89 W5NE89 PTHR11388:SF133 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER-RELATED active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011172.1|UniProtKB=W5MZB7 W5MZB7 PTHR16356:SF1 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 TMCO6 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000008874.1|UniProtKB=W5MQZ4 W5MQZ4 PTHR10560:SF1 THROMBOPOIETIN THROMBOPOIETIN ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000015660.1|UniProtKB=W5NF69 W5NF69 PTHR15944:SF3 FARNESYLCYSTEINE LYASE PRENYLCYSTEINE OXIDASE 1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056 metabolite interconversion enzyme#PC00262;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000009948.1|UniProtKB=W5MUV7 W5MUV7 PTHR46487:SF1 DNA REPAIR PROTEIN XRCC3 DNA REPAIR PROTEIN XRCC3 four-way junction DNA binding#GO:0000400;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 telomere organization#GO:0032200;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;cellular process#GO:0009987;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 nucleus#GO:0005634;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014040.1|UniProtKB=W5N9J6 W5N9J6 PTHR45809:SF1 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 2 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000008737.1|UniProtKB=W5MQH8 W5MQH8 PTHR12894:SF29 CNH DOMAIN CONTAINING TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1 HOMOLOG localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;transport#GO:0006810;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;vesicle fusion#GO:0006906;organelle membrane fusion#GO:0090174;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000010526.1|UniProtKB=W5MWY9 W5MWY9 PTHR23351:SF10 FOS TRANSCRIPTION FACTOR-RELATED JUN DIMERIZATION PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302 LEPOC|Ensembl=ENSLOCG00000007205.1|UniProtKB=W5MK10 W5MK10 PTHR23001:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2 translation factor activity#GO:0180051;translation initiation factor binding#GO:0031369;translation initiation factor activity#GO:0003743;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;protein binding#GO:0005515;RNA binding#GO:0003723 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translational initiation#GO:0002183;translational initiation#GO:0006413;translation#GO:0006412;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000014299.1|UniProtKB=W5NAE7 W5NAE7 PTHR10117:SF76 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 5 alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;metal ion transport#GO:0030001;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 LEPOC|Ensembl=ENSLOCG00000001566.1|UniProtKB=W5M082 W5M082 PTHR15201:SF1 CRSP70 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000008572.1|UniProtKB=W5MPW5 W5MPW5 PTHR11054:SF0 6-PHOSPHOGLUCONOLACTONASE 6-PHOSPHOGLUCONOLACTONASE 6-phosphogluconolactonase activity#GO:0017057;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleobase-containing small molecule metabolic process#GO:0055086;pentose-phosphate shunt, oxidative branch#GO:0009051;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004174.1|UniProtKB=W5M9E0 W5M9E0 PTHR11353:SF21 CHAPERONIN CHAPERONIN CONTAINING TCP1 SUBUNIT 6A-RELATED macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 protein folding chaperone complex#GO:0101031;chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 chaperonin#PC00073 LEPOC|Ensembl=ENSLOCG00000008350.1|UniProtKB=W5MP30 W5MP30 PTHR15297:SF2 IMMUNOGLOBULIN SUPERFAMILY MEMBER 6 IMMUNOGLOBULIN SUPERFAMILY MEMBER 6 immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000002470.1|UniProtKB=W5M3G4 W5M3G4 PTHR11640:SF49 NEPHRIN KIN OF IRRE-LIKE PROTEIN 3 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 synapse assembly#GO:0007416;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;system development#GO:0048731;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000012290.1|UniProtKB=W5N3B0 W5N3B0 PTHR22792:SF43 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 4B mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008188.1|UniProtKB=W5MNK9 W5MNK9 PTHR45670:SF13 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;response to stress#GO:0006950 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000006286.1|UniProtKB=W5MGT5 W5MGT5 PTHR15744:SF1 BLOM7 KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012124.1|UniProtKB=W5N2Q8 W5N2Q8 PTHR31728:SF2 ABRAXAS FAMILY MEMBER BRCA1-A COMPLEX SUBUNIT ABRAXAS 1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;microtubule binding#GO:0008017;protein binding#GO:0005515 organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;organelle localization#GO:0051640;organelle assembly#GO:0070925;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;nuclear division#GO:0000280;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;chromosome localization#GO:0050000;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;attachment of spindle microtubules to kinetochore#GO:0008608;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011346.1|UniProtKB=W5MZY9 W5MZY9 PTHR19849:SF7 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN PHOSPHOLIPASE A-2-ACTIVATING PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of cell motility#GO:2000145;protein metabolic process#GO:0019538;inflammatory response#GO:0006954;biological regulation#GO:0065007;macroautophagy#GO:0016236;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;macromolecule metabolic process#GO:0043170;positive regulation of locomotion#GO:0040017;ubiquitin-dependent protein catabolic process#GO:0006511;defense response#GO:0006952;regulation of neuron migration#GO:2001222;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cell migration#GO:0030334;response to stimulus#GO:0050896;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;positive regulation of transport#GO:0051050;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of transport#GO:0051049;regulation of localization#GO:0032879;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010040.1|UniProtKB=W5MV72 W5MV72 PTHR39063:SF1 ORAL-FACIAL-DIGITAL SYNDROME 1 PROTEIN HOMOLOG OFD1 CENTRIOLE AND CENTRIOLAR SATELLITE PROTEIN cellular process#GO:0009987;multicellular organismal process#GO:0032501;regionalization#GO:0003002;determination of bilateral symmetry#GO:0009855;specification of symmetry#GO:0009799;left/right pattern formation#GO:0060972;developmental process#GO:0032502;transport#GO:0006810;multicellular organism development#GO:0007275;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;determination of left/right symmetry#GO:0007368;microtubule-based movement#GO:0007018;cilium movement#GO:0003341;pattern specification process#GO:0007389;microtubule-based transport#GO:0099111;localization#GO:0051179;anatomical structure development#GO:0048856 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000008960.1|UniProtKB=W5MRA6 W5MRA6 PTHR24179:SF30 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 16A enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;enzyme inhibitor activity#GO:0004857 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000001337.1|UniProtKB=W5LZG9 W5LZG9 PTHR45614:SF30 MYB PROTEIN-RELATED MYB-RELATED PROTEIN B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell cycle#GO:0007049;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000006010.1|UniProtKB=W5MFU9 W5MFU9 PTHR19433:SF85 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 17-RELATED response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000012942.1|UniProtKB=W5N5N6 W5N5N6 PTHR23255:SF62 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transforming growth factor beta receptor activity#GO:0005024;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regionalization#GO:0003002;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to growth factor stimulus#GO:0071363;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;pattern specification process#GO:0007389;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;cell differentiation#GO:0030154;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;dorsal/ventral pattern formation#GO:0009953;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442 LEPOC|Ensembl=ENSLOCG00000017586.1|UniProtKB=W5NM32 W5NM32 PTHR23334:SF5 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016333.1|UniProtKB=W5NHQ5 W5NHQ5 PTHR18919:SF153 ACETYL-COA C-ACYLTRANSFERASE TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 transferase#PC00220;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000007151.1|UniProtKB=W5MJW0 W5MJW0 PTHR11675:SF7 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 4 glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009360.1|UniProtKB=W5MSQ7 W5MSQ7 PTHR10686:SF12 FOLATE TRANSPORTER REDUCED FOLATE TRANSPORTER active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;antiporter activity#GO:0015297;binding#GO:0005488;carboxylic acid binding#GO:0031406 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;vitamin transport#GO:0051180;dicarboxylic acid transport#GO:0006835;carboxylic acid transmembrane transport#GO:1905039;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;apical plasma membrane#GO:0016324;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;apical part of cell#GO:0045177 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008035.1|UniProtKB=W5MN01 W5MN01 PTHR13869:SF21 MYELIN P0 RELATED MYELIN PROTEIN ZERO-LIKE PROTEIN 2 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000000848.1|UniProtKB=W5LXU3 W5LXU3 PTHR11247:SF81 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 PALMITOYL-PROTEIN THIOESTERASE 1 palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824 developmental process#GO:0032502;transport#GO:0006810;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;localization#GO:0051179;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;import into cell#GO:0098657;establishment of localization#GO:0051234;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;endocytosis#GO:0006897 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009449.1|UniProtKB=W5MT25 W5MT25 PTHR10500:SF7 BETA-MICROSEMINOPROTEIN MICROSEMINOPROTEIN BETA intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014968.1|UniProtKB=W5NCS1 W5NCS1 PTHR11178:SF1 IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000010821.1|UniProtKB=W5MY03 W5MY03 PTHR12791:SF64 GOLGI SNARE BET1-RELATED BET1 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular component organization#GO:0016043;Golgi organization#GO:0007030;vesicle fusion#GO:0006906;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 membrane#GO:0016020;membrane protein complex#GO:0098796;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 SNARE protein#PC00034 LEPOC|Ensembl=ENSLOCG00000002757.1|UniProtKB=W5M4D6 W5M4D6 PTHR19282:SF514 TETRASPANIN UROPLAKIN-1B plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014443.1|UniProtKB=W5NAW8 W5NAW8 PTHR11875:SF108 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 1 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000013265.1|UniProtKB=W5N6T8 W5N6T8 PTHR13677:SF1 LD41638P PROTEIN DENND6A guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 positive regulation of cell adhesion#GO:0045785;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of cell-cell adhesion#GO:0022409;biological regulation#GO:0065007;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of cell adhesion#GO:0030155 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;recycling endosome#GO:0055037;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 LEPOC|Ensembl=ENSLOCG00000001856.1|UniProtKB=W5M192 W5M192 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;immune response#GO:0006955;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009083.1|UniProtKB=W5MRT1 W5MRT1 PTHR18966:SF36 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 1 potassium ion transmembrane transporter activity#GO:0015079;molecular transducer activity#GO:0060089;channel activity#GO:0015267;carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;metal ion transmembrane transporter activity#GO:0046873;neurotransmitter receptor activity#GO:0030594;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of trans-synaptic signaling#GO:0099177 transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839;sodium channel complex#GO:0034706;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group I pathway#P00041>GluR5#P01054;Ionotropic glutamate receptor pathway#P00037>KA1#P01004;Ionotropic glutamate receptor pathway#P00037>KA#P01026 LEPOC|Ensembl=ENSLOCG00000004257.1|UniProtKB=W5M9N2 W5M9N2 PTHR12245:SF3 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000002014.1|UniProtKB=W5M1S6 W5M1S6 PTHR10201:SF340 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-21 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 LEPOC|Ensembl=ENSLOCG00000001031.1|UniProtKB=W5LYG1 W5LYG1 PTHR11216:SF29 EH DOMAIN INTERSECTIN-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;intracellular transport#GO:0046907;endosomal transport#GO:0016197;receptor-mediated endocytosis#GO:0006898;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;import into cell#GO:0098657;clathrin-dependent endocytosis#GO:0072583;synaptic vesicle endocytosis#GO:0048488;endocytosis#GO:0006897;localization#GO:0051179;cellular localization#GO:0051641 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017525.1|UniProtKB=W5NLX1 W5NLX1 PTHR24232:SF0 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 3 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Blood coagulation#P00011>mPAR-3#P00452 LEPOC|Ensembl=ENSLOCG00000006255.1|UniProtKB=W5MGQ7 W5MGQ7 PTHR12771:SF16 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 3 response to external stimulus#GO:0009605;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;taxis#GO:0042330;response to chemical#GO:0042221;cell migration#GO:0016477;chemotaxis#GO:0006935;actin filament-based process#GO:0030029;cellular response to chemical stimulus#GO:0070887;cell chemotaxis#GO:0060326;supramolecular fiber organization#GO:0097435;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;locomotion#GO:0040011;response to stimulus#GO:0050896;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011258.1|UniProtKB=W5MZM6 W5MZM6 PTHR24025:SF31 DESMOGLEIN FAMILY MEMBER NEURAL-CADHERIN metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000003905.1|UniProtKB=W5M8G8 W5M8G8 PTHR10605:SF10 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000011455.1|UniProtKB=W5N0B5 W5N0B5 PTHR23509:SF4 PA-PL1 PHOSPHOLIPASE FAMILY SEC23-INTERACTING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;hydrolase activity#GO:0016787 spermatid differentiation#GO:0048515;spermatid development#GO:0007286;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;gamete generation#GO:0007276;cell differentiation#GO:0030154;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular process#GO:0009987;male gamete generation#GO:0048232 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000001110.1|UniProtKB=W5LYP7 W5LYP7 PTHR11782:SF33 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2 hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;nucleoside diphosphate metabolic process#GO:0009132;metabolic process#GO:0008152;organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 phosphatase#PC00181;hydrolase#PC00121;nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000010650.1|UniProtKB=W5MXD7 W5MXD7 PTHR10844:SF16 CAVEOLIN CAVEOLIN-3 protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;membrane assembly#GO:0071709;regulation of cytosolic calcium ion concentration#GO:0051480;cell differentiation#GO:0030154;homeostatic process#GO:0042592;developmental process#GO:0032502;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;regulation of membrane potential#GO:0042391;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;cellular component biogenesis#GO:0044085;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;cellular component assembly#GO:0022607;biological regulation#GO:0065007;membrane organization#GO:0061024;endomembrane system organization#GO:0010256 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;membrane raft#GO:0045121;membrane#GO:0016020;caveola#GO:0005901;cell periphery#GO:0071944;plasma membrane raft#GO:0044853;cell junction#GO:0030054;sarcolemma#GO:0042383;anchoring junction#GO:0070161;membrane microdomain#GO:0098857 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000017808.1|UniProtKB=W5NMQ3 W5NMQ3 PTHR46473:SF23 GH08155P GH08155P LEPOC|Ensembl=ENSLOCG00000016384.1|UniProtKB=W5NHX7 W5NHX7 PTHR46269:SF3 EPIPHYCAN-RELATED EPIPHYCAN animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;animal organ development#GO:0048513;skeletal system development#GO:0001501;multicellular organism development#GO:0007275;cartilage development#GO:0051216;connective tissue development#GO:0061448;system development#GO:0048731;bone development#GO:0060348;multicellular organismal process#GO:0032501;tissue development#GO:0009888 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 LEPOC|Ensembl=ENSLOCG00000003000.1|UniProtKB=W5M591 W5M591 PTHR46207:SF1 PROTEIN RCC2 PROTEIN RCC2 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267 positive regulation of cell cycle process#GO:0090068;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;macromolecule localization#GO:0033036;protein localization to kinetochore#GO:0034501;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;positive regulation of cell cycle#GO:0045787;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of chromosome segregation#GO:0051983;intracellular protein localization#GO:0008104;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015961.1|UniProtKB=W5NG96 W5NG96 PTHR11630:SF106 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM3 ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386 DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047;mitotic DNA replication#GO:1902969;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA replication initiation#GO:0006270;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987 MCM complex#GO:0042555;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000010126.1|UniProtKB=W5MVI5 W5MVI5 PTHR24278:SF37 COAGULATION FACTOR TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 1 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000010542.1|UniProtKB=W5MX14 W5MX14 PTHR11089:SF11 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000006751.1|UniProtKB=W5MIE8 W5MIE8 PTHR19960:SF25 TEKTIN TEKTIN-1 cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium movement involved in cell motility#GO:0060294;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell projection organization#GO:0030030;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;organelle assembly#GO:0070925;cilium organization#GO:0044782;cilium-dependent cell motility#GO:0060285 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000004327.1|UniProtKB=W5MA86 W5MA86 PTHR24035:SF137 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 6 cellular process#GO:0009987;cellular component organization#GO:0016043;membrane organization#GO:0061024;endocytosis#GO:0006897;membrane invagination#GO:0010324;transport#GO:0006810;phagocytosis#GO:0006909;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;establishment of localization#GO:0051234;import into cell#GO:0098657 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000002766.1|UniProtKB=W5M4E7 W5M4E7 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001304.1|UniProtKB=W5LZC7 W5LZC7 PTHR13178:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SGDH SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 5, MITOCHONDRIAL protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013616.1|UniProtKB=W5N830 W5N830 PTHR24055:SF335 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000010638.1|UniProtKB=W5MXE0 W5MXE0 PTHR13297:SF10 TBC1 DOMAIN FAMILY MEMBER 23-RELATED TBC1 DOMAIN FAMILY MEMBER 23 cellular localization#GO:0051641;anatomical structure development#GO:0048856;localization#GO:0051179;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;cytosolic transport#GO:0016482;endosomal transport#GO:0016197;establishment of localization#GO:0051234;animal organ development#GO:0048513;multicellular organism development#GO:0007275;transport#GO:0006810;developmental process#GO:0032502;intracellular transport#GO:0046907;embryo development#GO:0009790;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791 LEPOC|Ensembl=ENSLOCG00000010676.1|UniProtKB=W5MXG7 W5MXG7 PTHR24100:SF151 BUTYROPHILIN BUTYROPHILIN-LIKE 12 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;T cell receptor signaling pathway#GO:0050852;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;signaling#GO:0023052;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011537.1|UniProtKB=W5N0P5 W5N0P5 PTHR24416:SF91 TYROSINE-PROTEIN KINASE RECEPTOR EPIDERMAL GROWTH FACTOR RECEPTOR binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein binding#GO:0005515;protein kinase activity#GO:0004672;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;hormone binding#GO:0042562;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199 neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;multicellular organism development#GO:0007275;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;nervous system development#GO:0007399;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;ERBB signaling pathway#GO:0038127;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;epidermal growth factor receptor signaling pathway#GO:0007173;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;system development#GO:0048731;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 signaling receptor complex#GO:0043235;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>EGFR#P00466;EGF receptor signaling pathway#P00018>EGFR#P00542;Gonadotropin-releasing hormone receptor pathway#P06664>EGFR#P06843 LEPOC|Ensembl=ENSLOCG00000012293.1|UniProtKB=W5N3C2 W5N3C2 PTHR24416:SF343 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 4 catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;fibroblast growth factor binding#GO:0017134;signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;growth factor binding#GO:0019838;protein kinase activity#GO:0004672;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of lipid metabolic process#GO:0019216;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;regulation of biosynthetic process#GO:0009889;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of lipid biosynthetic process#GO:0046890;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;regulation of steroid biosynthetic process#GO:0050810;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;regulation of ERK1 and ERK2 cascade#GO:0070372 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 LEPOC|Ensembl=ENSLOCG00000014318.1|UniProtKB=W5NAH4 W5NAH4 PTHR22906:SF43 PROPERDIN PROPERDIN LEPOC|Ensembl=ENSLOCG00000009578.1|UniProtKB=W5MTJ5 W5MTJ5 PTHR43220:SF21 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41A LEPOC|Ensembl=ENSLOCG00000012230.1|UniProtKB=W5N343 W5N343 PTHR12217:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 2D EUKARYOTIC TRANSLATION INITIATION FACTOR 2D translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translational initiation#GO:0002183;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000013901.1|UniProtKB=W5N930 W5N930 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED LEPOC|Ensembl=ENSLOCG00000014429.1|UniProtKB=W5NAV0 W5NAV0 PTHR47136:SF1 SYNEMIN SYNEMIN cytoskeletal protein binding#GO:0008092;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198;protein binding#GO:0005515 system process#GO:0003008;nervous system process#GO:0050877;neuromuscular process#GO:0050905;muscle contraction#GO:0006936;multicellular organismal process#GO:0032501;striated muscle contraction#GO:0006941;skeletal muscle contraction#GO:0003009;muscle system process#GO:0003012 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;contractile muscle fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;sarcolemma#GO:0042383;intermediate filament#GO:0005882;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003029.1|UniProtKB=W5M5B0 W5M5B0 PTHR14102:SF4 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG BETA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cell cycle process#GO:0022402;cellular process#GO:0009987;centrosome cycle#GO:0007098;cell junction organization#GO:0034330;cytoskeleton organization#GO:0007010;establishment or maintenance of cell polarity#GO:0007163;cell-cell junction organization#GO:0045216;cell-cell junction maintenance#GO:0045217;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023 apical plasma membrane#GO:0016324;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transferase complex#GO:1990234;apical part of cell#GO:0045177;protein kinase complex#GO:1902911 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000011888.1|UniProtKB=W5N1V7 W5N1V7 PTHR23057:SF0 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000015311.1|UniProtKB=W5NDY0 W5NDY0 PTHR45882:SF2 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 3 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001548.1|UniProtKB=W5M064 W5M064 PTHR15359:SF7 IG-LIKE DOMAIN-CONTAINING PROTEIN CALMODULIN REGULATOR PROTEIN PCP4 cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calmodulin binding#GO:0005516 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 LEPOC|Ensembl=ENSLOCG00000000847.1|UniProtKB=W5LXU4 W5LXU4 PTHR24031:SF762 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A-II protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular protein-containing complex#GO:0140535;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000005382.1|UniProtKB=W5MDN0 W5MDN0 PTHR47025:SF30 AUTOIMMUNE REGULATOR AUTOIMMUNE REGULATOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;histone binding#GO:0042393;double-stranded DNA binding#GO:0003690;protein binding#GO:0005515;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488 positive regulation of macromolecule metabolic process#GO:0010604;lymphocyte activation#GO:0046649;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;multicellular organism development#GO:0007275;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;cell development#GO:0048468;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;lymphocyte mediated immunity#GO:0002449;positive regulation of macromolecule biosynthetic process#GO:0010557;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;immune response#GO:0006955;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;T cell differentiation#GO:0030217;animal organ development#GO:0048513;morphogenesis of an epithelium#GO:0002009;humoral immune response#GO:0006959;positive regulation of transcription by RNA polymerase II#GO:0045944;immune effector process#GO:0002252;cell differentiation#GO:0030154;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;mononuclear cell differentiation#GO:1903131;leukocyte mediated immunity#GO:0002443;immune system development#GO:0002520;positive regulation of metabolic process#GO:0009893;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;tissue development#GO:0009888;adaptive immune response#GO:0002250;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of leukocyte migration#GO:0002685;leukocyte activation#GO:0045321;regulation of DNA-templated transcription#GO:0006355;regulation of cell motility#GO:2000145;positive regulation of biosynthetic process#GO:0009891;tissue morphogenesis#GO:0048729;system development#GO:0048731;regulation of lymphocyte migration#GO:2000401;cell activation#GO:0001775;lymphocyte differentiation#GO:0030098;T cell mediated immunity#GO:0002456 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001175.1|UniProtKB=W5LYX0 W5LYX0 PTHR11848:SF249 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;transforming growth factor beta receptor signaling pathway#GO:0007179;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;circulatory system development#GO:0072359;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to transforming growth factor beta stimulus#GO:0071560;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cellular response to growth factor stimulus#GO:0071363;animal gross anatomical part developmental process#GO:0160108;response to transforming growth factor beta#GO:0071559 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000003582.1|UniProtKB=W5M793 W5M793 PTHR10334:SF73 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN LCCL DOMAIN-CONTAINING 1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015301.1|UniProtKB=W5NDW5 W5NDW5 PTHR21559:SF24 DYSTROGLYCAN-RELATED PEPTIDASE S72 DOMAIN-CONTAINING PROTEIN cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 system development#GO:0048731;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection organization#GO:0120036;epithelium development#GO:0060429;tissue development#GO:0009888;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;neuron projection development#GO:0031175 sarcolemma#GO:0042383;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000017826.1|UniProtKB=W5NMS0 W5NMS0 PTHR21824:SF4 TRANSMEMBRANE PROTEIN 177 TRANSMEMBRANE PROTEIN 177 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000015936.1|UniProtKB=W5NG64 W5NG64 PTHR45796:SF11 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P2 ISOFORM X1 DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;skeletal muscle tissue development#GO:0007519;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;tissue development#GO:0009888;regulation of nucleobase-containing compound metabolic process#GO:0019219;striated muscle tissue development#GO:0014706;developmental process#GO:0032502;muscle organ development#GO:0007517;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000017151.1|UniProtKB=W5NKN6 W5NKN6 PTHR32026:SF20 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24 ISOFORM X1-RELATED transferase#PC00220;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000011983.1|UniProtKB=W5N286 W5N286 PTHR45718:SF5 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTION ACTIVATOR GLI3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;smoothened signaling pathway#GO:0007224;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus repressor#P00687;Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690 LEPOC|Ensembl=ENSLOCG00000002509.1|UniProtKB=W5M3K4 W5M3K4 PTHR46022:SF3 PROTEIN PATCHED PROTEIN PATCHED HOMOLOG 2 signaling receptor binding#GO:0005102;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000004516.1|UniProtKB=W5MAK6 W5MAK6 PTHR21616:SF2 CENTROSOME SPINDLE POLE ASSOCIATED PROTEIN CENTROSOME AND SPINDLE POLE-ASSOCIATED PROTEIN 1 regulation of cellular process#GO:0050794;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;positive regulation of cell cycle process#GO:0090068;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;intracellular organelle#GO:0043229 centromere DNA-binding protein#PC00071 LEPOC|Ensembl=ENSLOCG00000000817.1|UniProtKB=W5LXQ1 W5LXQ1 PTHR10071:SF154 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-4 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>GATA2/4#P06859 LEPOC|Ensembl=ENSLOCG00000011085.1|UniProtKB=W5MZ04 W5MZ04 PTHR23065:SF8 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 F-BAR DOMAIN ONLY PROTEIN 2 cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;synaptic vesicle endocytosis#GO:0048488;clathrin-dependent endocytosis#GO:0072583;protein-containing complex assembly#GO:0065003;endocytosis#GO:0006897;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;receptor-mediated endocytosis#GO:0006898;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;cellular component assembly#GO:0022607 clathrin-coated vesicle#GO:0030136;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000015833.1|UniProtKB=W5NFT2 W5NFT2 PTHR14484:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 COILED-COIL DOMAIN-CONTAINING PROTEIN 71L LEPOC|Ensembl=ENSLOCG00000011163.1|UniProtKB=W5MZA6 W5MZA6 PTHR12329:SF52 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 regulation of biological quality#GO:0065008;protein stabilization#GO:0050821;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 Apoptosis signaling pathway#P00006>Bag#P00278 LEPOC|Ensembl=ENSLOCG00000017326.1|UniProtKB=W5NLC2 W5NLC2 PTHR37557:SF4 115 KDA PROTEIN IN TYPE-1 RETROTRANSPOSABLE ELEMENT R1DM-LIKE PROTEIN-RELATED-RELATED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000004936.1|UniProtKB=W5MC29 W5MC29 PTHR12966:SF0 NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13 membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000003707.1|UniProtKB=W5M7S9 W5M7S9 PTHR45999:SF1 UNC-13-4A, ISOFORM B BAI1-ASSOCIATED PROTEIN 3 binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;regulation of localization#GO:0032879;regulation of transport#GO:0051049;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of neurotransmitter secretion#GO:0046928;positive regulation of cell communication#GO:0010647;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;positive regulation of signaling#GO:0023056;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;positive regulation of synaptic transmission#GO:0050806 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;late endosome membrane#GO:0031902;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;trans-Golgi network membrane#GO:0032588;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;secretory vesicle#GO:0099503 LEPOC|Ensembl=ENSLOCG00000003281.1|UniProtKB=W5M659 W5M659 PTHR31767:SF0 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-LIKE SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-LIKE SUBUNIT voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000008579.1|UniProtKB=W5MPX4 W5MPX4 PTHR21705:SF6 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 1A LEPOC|Ensembl=ENSLOCG00000011098.1|UniProtKB=W5MZ21 W5MZ21 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000008339.1|UniProtKB=W5MP20 W5MP20 PTHR12890:SF0 DREV PROTEIN PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000008029.1|UniProtKB=W5MMZ6 W5MMZ6 PTHR10110:SF90 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 3 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885 cluster of actin-based cell projections#GO:0098862;cell projection membrane#GO:0031253;apical part of cell#GO:0045177;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;brush border membrane#GO:0031526;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;brush border#GO:0005903;cell periphery#GO:0071944;membrane#GO:0016020;apical plasma membrane#GO:0016324 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009680.1|UniProtKB=W5MTW5 W5MTW5 PTHR21519:SF1 PDZ DOMAIN-CONTAINING PROTEIN 8 PDZ DOMAIN-CONTAINING PROTEIN 8 calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592 organelle membrane contact site#GO:0044232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007900.1|UniProtKB=W5MMI3 W5MMI3 PTHR32023:SF2 PILR ALPHA-ASSOCIATED NEURAL PROTEIN PILR ALPHA-ASSOCIATED NEURAL PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011399.1|UniProtKB=W5N055 W5N055 PTHR12709:SF5 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;DNA-templated transcription elongation#GO:0006354;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 LEPOC|Ensembl=ENSLOCG00000011807.1|UniProtKB=W5N1L1 W5N1L1 PTHR23235:SF141 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 15 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002993.1|UniProtKB=W5M566 W5M566 PTHR16489:SF16 GH11727P PROTEIN PHOSPHATASE 1, REGULATORY SUBUNIT 15B molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000009876.1|UniProtKB=W5MUL4 W5MUL4 PTHR12566:SF8 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 2 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;translation factor activity#GO:0180051;translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730 negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of translation#GO:0017148 cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;nucleus#GO:0005634;neuron projection#GO:0043005;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000010027.1|UniProtKB=W5MV52 W5MV52 PTHR10279:SF11 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 2 enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000015705.1|UniProtKB=W5NFC4 W5NFC4 PTHR34394:SF1 SIMILAR TO RIKEN CDNA 2310022B05 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 198 LEPOC|Ensembl=ENSLOCG00000004946.1|UniProtKB=W5MC49 W5MC49 PTHR42881:SF4 PROLYL ENDOPEPTIDASE PROLYL ENDOPEPTIDASE ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000017466.1|UniProtKB=W5NLR2 W5NLR2 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000008417.1|UniProtKB=W5MPC3 W5MPC3 PTHR11860:SF120 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 5-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000009002.1|UniProtKB=W5MRH4 W5MRH4 PTHR11782:SF37 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 7 ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;ribonucleoside diphosphate metabolic process#GO:0009185;nucleoside diphosphate catabolic process#GO:0009134;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;ribonucleoside diphosphate catabolic process#GO:0009191;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;nucleoside diphosphate metabolic process#GO:0009132;ribonucleotide metabolic process#GO:0009259 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000010321.1|UniProtKB=W5MWB8 W5MWB8 PTHR24044:SF421 NOTCH LIGAND FAMILY MEMBER PROTEIN JAGGED-2 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 intercellular signal molecule#PC00207 Notch signaling pathway#P00045>Next#P01103;Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Serrate#P01104 LEPOC|Ensembl=ENSLOCG00000014440.1|UniProtKB=W5NAW4 W5NAW4 PTHR32267:SF2 T-CELL LEUKEMIA TRANSLOCATION-ALTERED GENE PROTEIN T-CELL LEUKEMIA TRANSLOCATION-ALTERED GENE PROTEIN LEPOC|Ensembl=ENSLOCG00000005211.1|UniProtKB=W5MD11 W5MD11 PTHR24061:SF441 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 2.1-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000014950.1|UniProtKB=W5NCQ0 W5NCQ0 PTHR21208:SF0 ADP-DEPENDENT GLUCOKINASE ADP-DEPENDENT GLUCOKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 glucose metabolic process#GO:0006006;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000011734.1|UniProtKB=W5N1C1 W5N1C1 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 aspartic protease#PC00053;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008088.1|UniProtKB=W5MN61 W5MN61 PTHR10339:SF32 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 5-RELATED glycosyltransferase activity#GO:0016757;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016092.1|UniProtKB=W5NGS0 W5NGS0 PTHR13817:SF101 TITIN IMMUNOGLOBULIN SUPERFAMILY, MEMBER 9A structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009774.1|UniProtKB=W5MU83 W5MU83 PTHR11216:SF57 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;localization within membrane#GO:0051668;endocytosis#GO:0006897;endocytic recycling#GO:0032456;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;recycling endosome#GO:0055037 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006202.1|UniProtKB=W5MGI3 W5MGI3 PTHR13161:SF15 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT SPLICING FACTOR, SUPPRESSOR OF WHITE-APRICOT HOMOLOG macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011240.1|UniProtKB=W5MZL7 W5MZL7 PTHR16212:SF4 FOCADHESIN FAMILY MEMBER FOCADHESIN LEPOC|Ensembl=ENSLOCG00000017701.1|UniProtKB=W5NME7 W5NME7 PTHR24229:SF38 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;binding#GO:0005488;neuropeptide receptor activity#GO:0008188;molecular transducer activity#GO:0060089 cell communication#GO:0007154;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;response to estradiol#GO:0032355;biological regulation#GO:0065007;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000011177.1|UniProtKB=W5MZC3 W5MZC3 PTHR16200:SF5 RING ZINC FINGER PROTEIN ARK2N aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003145.1|UniProtKB=W5M5P7 W5M5P7 PTHR33722:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT DELTA sperm capacitation#GO:0048240;male gamete generation#GO:0048232;developmental maturation#GO:0021700;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;cell maturation#GO:0048469;developmental process#GO:0032502;spermatogenesis#GO:0007283;flagellated sperm motility#GO:0030317;cell development#GO:0048468;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;gamete generation#GO:0007276;microtubule-based movement#GO:0007018;cell motility#GO:0048870;cell differentiation#GO:0030154;sperm motility#GO:0097722;germ cell development#GO:0007281;anatomical structure maturation#GO:0071695;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;cilium-dependent cell motility#GO:0060285;spermatid development#GO:0007286;cilium movement#GO:0003341;sexual reproduction#GO:0019953;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;sperm principal piece#GO:0097228;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;9+2 motile cilium#GO:0097729;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;monoatomic ion channel complex#GO:0034702;sperm flagellum#GO:0036126;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351 voltage-gated ion channel#PC00241;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006071.1|UniProtKB=W5MG21 W5MG21 PTHR22883:SF514 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC12 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096 localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012437.1|UniProtKB=W5N3U9 W5N3U9 PTHR28659:SF1 RETICULON-LIKE PROTEIN RETICULOPHAGY REGULATOR 3 LEPOC|Ensembl=ENSLOCG00000003206.1|UniProtKB=W5M5Y2 W5M5Y2 PTHR20843:SF2 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 12 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000003371.1|UniProtKB=W5M6H0 W5M6H0 PTHR21162:SF0 P53 AND DNA DAMAGE-REGULATED PROTEIN P53 AND DNA DAMAGE-REGULATED PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000013686.1|UniProtKB=W5N8B8 W5N8B8 PTHR12692:SF2 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT MAGT1 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;establishment of localization#GO:0051234;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;magnesium ion transport#GO:0015693;metabolic process#GO:0008152;transport#GO:0006810;glycoprotein metabolic process#GO:0009100;metal ion transport#GO:0030001;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000012888.1|UniProtKB=W5N5F8 W5N5F8 PTHR24412:SF192 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006410.1|UniProtKB=W5MH85 W5MH85 PTHR22950:SF192 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 7 L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 LEPOC|Ensembl=ENSLOCG00000005714.1|UniProtKB=W5MEW3 W5MEW3 PTHR15154:SF2 HAMARTIN HAMARTIN negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;regulation of cell population proliferation#GO:0042127;negative regulation of cell communication#GO:0010648;negative regulation of cell population proliferation#GO:0008285;regulation of TOR signaling#GO:0032006;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC1#P04495;p53 pathway by glucose deprivation#P04397>TSC1#P04645 LEPOC|Ensembl=ENSLOCG00000016581.1|UniProtKB=W5NIM8 W5NIM8 PTHR11444:SF1 ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE FUMARATE HYDRATASE, MITOCHONDRIAL catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 lyase#PC00144 TCA cycle#P00051>Fumarase#P01271 LEPOC|Ensembl=ENSLOCG00000014215.1|UniProtKB=W5NA90 W5NA90 PTHR23317:SF81 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 11 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of filopodium assembly#GO:0051489;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cell projection assembly#GO:0060491;positive regulation of cell projection organization#GO:0031346;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of intracellular signal transduction#GO:1902531;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000012891.1|UniProtKB=W5N5H3 W5N5H3 PTHR48099:SF1 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000015478.1|UniProtKB=W5NEJ1 W5NEJ1 PTHR12298:SF8 PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED US5 ASSEMBLY CHAPERONE PDCD2 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008220.1|UniProtKB=W5MNM3 W5MNM3 PTHR13388:SF29 DETONATOR, ISOFORM E TRANSMEMBRANE PROTEIN 132A ISOFORM X1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014500.1|UniProtKB=W5NB41 W5NB41 PTHR23511:SF2 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2B cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;regulation of transport#GO:0051049;intracellular calcium ion homeostasis#GO:0006874;regulation of localization#GO:0032879;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;monoatomic ion homeostasis#GO:0050801;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of secretion#GO:0051046;inorganic ion homeostasis#GO:0098771;regulation of signaling#GO:0023051;calcium ion homeostasis#GO:0055074;regulation of neurotransmitter transport#GO:0051588;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of cell communication#GO:0010646;homeostatic process#GO:0042592;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of neurotransmitter secretion#GO:0046928;regulation of cytosolic calcium ion concentration#GO:0051480;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873 cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000018181.1|UniProtKB=W5NNS3 W5NNS3 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008341.1|UniProtKB=W5MP23 W5MP23 PTHR24012:SF719 RNA BINDING PROTEIN RNA-BINDING PROTEIN 19-RELATED RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000017553.1|UniProtKB=W5NLZ9 W5NLZ9 PTHR15314:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P20 RIBONUCLEASE P PROTEIN SUBUNIT P20 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000017071.1|UniProtKB=W5NKD7 W5NKD7 PTHR14042:SF22 DOPEY-RELATED PROTEIN DOP1A establishment of localization in cell#GO:0051649;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;retrograde transport, vesicle recycling within Golgi#GO:0000301;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000002486.1|UniProtKB=W5M3G1 W5M3G1 PTHR16839:SF1 GALANIN GALANIN PEPTIDES signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;neuropeptide hormone activity#GO:0005184;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 secretory vesicle#GO:0099503;endomembrane system#GO:0012505;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;cell body#GO:0044297;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;extracellular region#GO:0005576;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 LEPOC|Ensembl=ENSLOCG00000017569.1|UniProtKB=W5NM15 W5NM15 PTHR31746:SF3 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229B LEPOC|Ensembl=ENSLOCG00000002121.1|UniProtKB=W5M250 W5M250 PTHR23411:SF42 TAPASIN IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013662.1|UniProtKB=W5N884 W5N884 PTHR15601:SF15 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001284.1|UniProtKB=W5LZC4 W5LZC4 PTHR11492:SF2 NUCLEAR FACTOR I NUCLEAR FACTOR 1 C-TYPE transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000007711.1|UniProtKB=W5MLV4 W5MLV4 HECTD4 PTHR46435:SF1 E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED chemical homeostasis#GO:0048878;carbohydrate homeostasis#GO:0033500;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000007520.1|UniProtKB=W5ML64 W5ML64 PTHR23033:SF9 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-A galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004473.1|UniProtKB=W5MAD7 W5MAD7 MARCHF2 PTHR46065:SF4 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF2 ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000006328.1|UniProtKB=W5MGX9 W5MGX9 PTHR15735:SF11 FCH AND DOUBLE SH3 DOMAINS PROTEIN F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 2 phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 vesicle-mediated transport#GO:0016192;regulation of actin cytoskeleton organization#GO:0032956;synaptic signaling#GO:0099536;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;regulation of anatomical structure size#GO:0090066;neuromuscular synaptic transmission#GO:0007274;regulation of cellular component organization#GO:0051128;endocytosis#GO:0006897;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;regulation of actin filament organization#GO:0110053;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;regulation of actin filament-based process#GO:0032970;transport#GO:0006810;regulation of protein polymerization#GO:0032271;anterograde trans-synaptic signaling#GO:0098916;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;chemical synaptic transmission#GO:0007268;regulation of supramolecular fiber organization#GO:1902903;clathrin-dependent endocytosis#GO:0072583;cell communication#GO:0007154;localization#GO:0051179;trans-synaptic signaling#GO:0099537 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;neuromuscular junction#GO:0031594;recycling endosome#GO:0055037 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000005982.1|UniProtKB=W5MFS2 W5MFS2 PTHR14882:SF4 COILED-COIL DOMAIN-CONTAINING 74A COILED-COIL DOMAIN-CONTAINING PROTEIN 92 regulation of immune response#GO:0050776;inflammatory response#GO:0006954;regulation of defense response#GO:0031347;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;intracellular receptor signaling pathway#GO:0030522;regulation of response to biotic stimulus#GO:0002831;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;positive regulation of response to biotic stimulus#GO:0002833;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;activation of innate immune response#GO:0002218;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune system process#GO:0002376;cytoplasmic pattern recognition receptor signaling pathway#GO:0002753;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization or biogenesis#GO:0071840;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;cellular process#GO:0009987;cellular component assembly#GO:0022607;regulation of response to external stimulus#GO:0032101 centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000012854.1|UniProtKB=W5N5B5 W5N5B5 PTHR45832:SF3 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE LEPOC|Ensembl=ENSLOCG00000001491.1|UniProtKB=W5LZZ5 W5LZZ5 PTHR45704:SF16 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE LEPOC|Ensembl=ENSLOCG00000016439.1|UniProtKB=W5NI45 W5NI45 PTHR31226:SF1 TRANSMEMBRANE PROTEIN 117 TRANSMEMBRANE PROTEIN 117 biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;apoptotic signaling pathway#GO:0097190;signaling#GO:0023052;regulation of cellular process#GO:0050794;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976 LEPOC|Ensembl=ENSLOCG00000010677.1|UniProtKB=W5MXG8 W5MXG8 PTHR10177:SF59 CYCLINS CYCLIN-G1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>CYCLIN G#G04715;p53 pathway#P00059>Cyclin G#G04689;p53 pathway feedback loops 2#P04398>cyclin G#P04662 LEPOC|Ensembl=ENSLOCG00000016307.1|UniProtKB=W5NHM0 W5NHM0 PTHR13448:SF0 TRANSMEMBRANE PROTEIN 214 TRANSMEMBRANE PROTEIN 214 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002962.1|UniProtKB=W5M553 W5M553 PTHR31167:SF3 SPINDLE AND CENTRIOLE ASSOCIATED PROTEIN 1 SPICE1 SPINDLE AND CENTRIOLE-ASSOCIATED PROTEIN 1 biological regulation#GO:0065007;mitotic sister chromatid segregation#GO:0000070;regulation of organelle assembly#GO:1902115;mitotic spindle assembly#GO:0090307;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle assembly#GO:0070925;organelle localization#GO:0051640;regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;regulation of cellular component organization#GO:0051128;mitotic spindle organization#GO:0007052;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;nuclear division#GO:0000280 spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000011433.1|UniProtKB=W5N092 W5N092 PTHR12411:SF917 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L, LIKE-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000017539.1|UniProtKB=W5NLY5 W5NLY5 PTHR11829:SF215 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN B2 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000011063.1|UniProtKB=W5MYX3 W5MYX3 PTHR45660:SF13 HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR DNA binding#GO:0003677;histone modifying activity#GO:0140993;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;methyltransferase activity#GO:0008168;histone methyltransferase activity#GO:0042054;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000001020.1|UniProtKB=W5LYE1 W5LYE1 PTHR11782:SF38 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110 nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate catabolic process#GO:0046434;metabolic process#GO:0008152;nucleoside diphosphate metabolic process#GO:0009132;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;nucleoside diphosphate catabolic process#GO:0009134;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000000696.1|UniProtKB=W5LXB3 W5LXB3 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000015881.1|UniProtKB=W5NFZ7 W5NFZ7 PTHR42799:SF2 MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000008690.1|UniProtKB=W5MQB2 W5MQB2 PTHR21540:SF3 RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2 E3 UBIQUITIN-PROTEIN LIGASE ZSWIM2 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011923.1|UniProtKB=W5N209 W5N209 PTHR14167:SF50 SH3 DOMAIN-CONTAINING ENDOPHILIN-A1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;membrane organization#GO:0061024;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;endocytosis#GO:0006897;synaptic vesicle endocytosis#GO:0048488;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641 presynapse#GO:0098793;cytosol#GO:0005829;cytoplasm#GO:0005737;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010031.1|UniProtKB=W5MV62 W5MV62 PTHR24174:SF4 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 1A protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;ephrin receptor signaling pathway#GO:0048013;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012781.1|UniProtKB=W5N520 W5N520 PTHR12191:SF22 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP6 transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804 transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002969.1|UniProtKB=W5M536 W5M536 PTHR23292:SF48 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR SI:CH211-202H22.9 transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;side of membrane#GO:0098552;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;lysosomal membrane#GO:0005765;nucleus#GO:0005634;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;cytoplasmic side of membrane#GO:0098562;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013050.1|UniProtKB=W5N612 W5N612 PTHR46272:SF1 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G PROTEIN-COUPLED RECEPTOR 142 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000018203.1|UniProtKB=W5NNU5 W5NNU5 PTHR26451:SF886 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593;system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007159.1|UniProtKB=W5MJV4 W5MJV4 PTHR39654:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 75A-LIKE ISOFORM X1 LEUCINE RICH REPEAT CONTAINING 75A LEPOC|Ensembl=ENSLOCG00000002238.1|UniProtKB=W5M2J6 W5M2J6 PTHR12682:SF11 ARCHEASE TRNA-SPLICING LIGASE-ACTIVATING FACTOR ARCHEASE catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000013065.1|UniProtKB=W5N638 W5N638 PTHR45734:SF5 TENSIN TENSIN-3 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003507.1|UniProtKB=W5M6Z4 W5M6Z4 PTHR11594:SF1 40S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN ES27 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;nucleic acid biosynthetic process#GO:0141187;translation#GO:0006412;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 LEPOC|Ensembl=ENSLOCG00000016180.1|UniProtKB=W5NH34 W5NH34 PTHR24070:SF467 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1B catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 regulation of synaptic vesicle exocytosis#GO:2000300;signaling#GO:0023052;regulation of neurotransmitter secretion#GO:0046928;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;negative regulation of biological process#GO:0048519;regulation of secretion by cell#GO:1903530;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;regulation of neurotransmitter transport#GO:0051588;cellular response to chemical stimulus#GO:0070887;intracellular signaling cassette#GO:0141124;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;regulation of exocytosis#GO:0017157;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;regulation of secretion#GO:0051046;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular response to nitrogen compound#GO:1901699;negative regulation of cellular process#GO:0048523 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 LEPOC|Ensembl=ENSLOCG00000016076.1|UniProtKB=W5NGP8 W5NGP8 PTHR24241:SF82 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 1-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003407.1|UniProtKB=W5M6P5 W5M6P5 PTHR23257:SF987 SERINE-THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013480.1|UniProtKB=W5N7L7 W5N7L7 PTHR10075:SF147 BASIGIN RELATED PROTOGENIN cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004939.1|UniProtKB=W5MC32 W5MC32 PTHR12377:SF0 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000000276.1|UniProtKB=W5LVZ5 W5LVZ5 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013474.1|UniProtKB=W5N7K3 W5N7K3 PTHR46492:SF2 DYNEIN ASSEMBLY FACTOR 4, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 4 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;binding#GO:0005488;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134;nuclear estrogen receptor binding#GO:0030331 determination of left/right symmetry#GO:0007368;microtubule-based movement#GO:0007018;organelle assembly#GO:0070925;pattern specification process#GO:0007389;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;axoneme assembly#GO:0035082;outer dynein arm assembly#GO:0036158;multicellular organismal process#GO:0032501;regionalization#GO:0003002;plasma membrane bounded cell projection organization#GO:0120036;specification of symmetry#GO:0009799;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;transport#GO:0006810;establishment of localization#GO:0051234;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;circulatory system development#GO:0072359;cell projection organization#GO:0030030;animal gross anatomical part developmental process#GO:0160108;inner dynein arm assembly#GO:0036159;cilium movement#GO:0003341;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;heart development#GO:0007507;cytoskeleton organization#GO:0007010;determination of bilateral symmetry#GO:0009855;left/right pattern formation#GO:0060972;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013904.1|UniProtKB=W5N941 W5N941 PTHR11616:SF124 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 3 active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811 cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000013460.1|UniProtKB=W5N7J1 W5N7J1 PTHR46294:SF3 SEGMENTATION PROTEIN EVEN-SKIPPED EVEN-SKIPPED-LIKE1 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007758.1|UniProtKB=W5MM16 W5MM16 PTHR48078:SF21 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED L-SERINE AMMONIA-LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;branched-chain amino acid biosynthetic process#GO:0009082;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 dehydratase#PC00091;lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000017981.1|UniProtKB=W5NN73 W5NN73 PTHR32358:SF1 TRANSCRIPTIONAL AND IMMUNE RESPONSE REGULATOR TRANSCRIPTIONAL AND IMMUNE RESPONSE REGULATOR protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;immune effector process#GO:0002252;negative regulation of Notch signaling pathway#GO:0045746;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;immune response#GO:0006955;cell activation involved in immune response#GO:0002263;negative regulation of cell communication#GO:0010648;immune system process#GO:0002376;negative regulation of signaling#GO:0023057;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;cell activation#GO:0001775;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000015565.1|UniProtKB=W5NEV3 W5NEV3 PTHR48071:SF37 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000007429.1|UniProtKB=W5MKV8 W5MKV8 BOP1 PTHR17605:SF0 RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN RIBOSOME BIOGENESIS PROTEIN BOP1 rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000015864.1|UniProtKB=W5NFX5 W5NFX5 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009598.1|UniProtKB=W5MTL5 W5MTL5 PTHR47266:SF40 ENDONUCLEASE-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000006159.1|UniProtKB=W5MGC9 W5MGC9 PTHR26451:SF905 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 2G3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012562.1|UniProtKB=W5N4A8 W5N4A8 PTHR46644:SF4 DNA REPAIR PROTEIN XRCC2 DNA REPAIR PROTEIN XRCC2 binding#GO:0005488;nucleic acid binding#GO:0003676;four-way junction DNA binding#GO:0000400;DNA binding#GO:0003677 DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;replication fork#GO:0005657;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000004182.1|UniProtKB=W5M9D0 W5M9D0 PTHR10462:SF61 GLYCOSYLTRANSFERASE-RELATED GLOBOSIDE ALPHA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1-RELATED glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000010929.1|UniProtKB=W5MYE6 W5MYE6 PTHR24361:SF342 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;PDGF signaling pathway#P00047>ERK#P01143;B cell activation#P00010>MEKK#P00369;FGF signaling pathway#P00021>MEKK1-5#P00634;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;Integrin signalling pathway#P00034>ERK#P00907 LEPOC|Ensembl=ENSLOCG00000018182.1|UniProtKB=W5NNS4 W5NNS4 PTHR15258:SF1 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 2 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;cellular process#GO:0009987;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000011832.1|UniProtKB=W5N1P4 W5N1P4 PTHR11960:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 1B RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000006361.1|UniProtKB=W5MH26 W5MH26 PTHR10814:SF33 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 7 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000015461.1|UniProtKB=W5NEH5 W5NEH5 PTHR22625:SF9 PLEXIN PLEXIN-B2 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;regulation of locomotion#GO:0040012;negative regulation of cell adhesion#GO:0007162;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;system development#GO:0048731;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;cellular component assembly#GO:0022607;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;regulation of axonogenesis#GO:0050770;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;synapse assembly#GO:0007416;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;positive regulation of axonogenesis#GO:0050772;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001197.1|UniProtKB=W5LZ19 W5LZ19 PTHR43899:SF14 RH59310P VERY-LONG-CHAIN 3-OXOACYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000012936.1|UniProtKB=W5N5N3 W5N5N3 PTHR13140:SF417 MYOSIN UNCONVENTIONAL MYOSIN-ID microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;transport#GO:0006810;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based movement#GO:0030048;cellular process#GO:0009987 microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000009805.1|UniProtKB=W5MUC5 W5MUC5 PTHR12732:SF0 UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING PCI DOMAIN-CONTAINING PROTEIN 2 RNA binding#GO:0003723;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;mRNA transport#GO:0051028;RNA localization#GO:0006403;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;macromolecule biosynthetic process#GO:0009059;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transport#GO:0006810;transcription by RNA polymerase II#GO:0006366;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;chromosome organization#GO:0051276;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;cellular component organization#GO:0016043;nucleic acid biosynthetic process#GO:0141187;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;mRNA export from nucleus#GO:0006406;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;DNA-templated transcription elongation#GO:0006354;organelle organization#GO:0006996;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;transcription export complex 2#GO:0070390;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000004882.1|UniProtKB=W5MBY1 W5MBY1 PTHR22635:SF0 RING FINGER PROTEIN 207 RING FINGER PROTEIN 207 Hsp70 protein binding#GO:0030544;protein binding#GO:0005515;heat shock protein binding#GO:0031072;transmembrane transporter binding#GO:0044325;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 regulation of heart contraction#GO:0008016;regulation of multicellular organismal process#GO:0051239;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;regulation of anatomical structure morphogenesis#GO:0022603;regulation of system process#GO:0044057;regulation of muscle contraction#GO:0006937 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471 LEPOC|Ensembl=ENSLOCG00000008232.1|UniProtKB=W5MNN5 W5MNN5 PTHR45710:SF8 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN CONTAINING 5A-RELATED cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000017930.1|UniProtKB=W5NN24 W5NN24 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000007943.1|UniProtKB=W5MMN7 W5MMN7 PTHR10736:SF1 BESTROPHIN BESTROPHIN-2A chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000017201.1|UniProtKB=W5NKV5 W5NKV5 PTHR11848:SF321 TGF-BETA FAMILY GROWTH_DIFFERENTIATION FACTOR 6-A molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000006068.1|UniProtKB=W5MG23 W5MG23 PTHR10383:SF16 SERINE INCORPORATOR SERINE INCORPORATOR 5 membrane#GO:0016020;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000014142.1|UniProtKB=W5N9W2 W5N9W2 PTHR13005:SF5 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN CYSTEINE-RICH HYDROPHOBIC DOMAIN-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000007439.1|UniProtKB=W5MKW7 W5MKW7 PTHR45897:SF5 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH AFFINITY CHOLINE TRANSPORTER 1 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;metabolic process#GO:0008152;biosynthetic process#GO:0009058;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003121.1|UniProtKB=W5M5L3 W5M5L3 PTHR45972:SF1 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 7A LEPOC|Ensembl=ENSLOCG00000000541.1|UniProtKB=W5LWU0 W5LWU0 PTHR14248:SF33 CYCLIN Y, ISOFORM A CYCLIN-Y molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical Wnt signaling pathway#GO:0060828 intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000003030.1|UniProtKB=W5M5B5 W5M5B5 PTHR24355:SF18 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;G protein-coupled receptor binding#GO:0001664;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin kinase#P00750;Parkinson disease#P00049>GRK#P01234;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK3#P05941 LEPOC|Ensembl=ENSLOCG00000012873.1|UniProtKB=W5N5E6 W5N5E6 PTHR16055:SF2 INTEGRATOR COMPLEX SUBUNIT 10 INTEGRATOR COMPLEX SUBUNIT 10 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;integrator complex#GO:0032039;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002516.1|UniProtKB=W5M3J1 W5M3J1 PTHR24248:SF14 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1D ADRENERGIC RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;regulation of multicellular organismal process#GO:0051239;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of system process#GO:0044057;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of anatomical structure size#GO:0090066;system process#GO:0003008;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cytosolic calcium ion concentration#GO:0007204;G protein-coupled receptor signaling pathway#GO:0007186;circulatory system process#GO:0003013;regulation of biological quality#GO:0065008;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000012816.1|UniProtKB=W5N570 W5N570 PTHR46750:SF1 KUNITZ-TYPE PROTEASE INHIBITOR 1 KUNITZ-TYPE PROTEASE INHIBITOR 1 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;external encapsulating structure organization#GO:0045229;animal gross anatomical part developmental process#GO:0160108;epidermis development#GO:0008544;extracellular structure organization#GO:0043062;developmental process#GO:0032502;epithelium development#GO:0060429;tissue development#GO:0009888;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000013681.1|UniProtKB=W5N8B3 W5N8B3 PTHR17039:SF0 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005528.1|UniProtKB=W5ME66 W5ME66 PTHR46370:SF1 GPALPP MOTIFS-CONTAINING PROTEIN 1 GPALPP MOTIFS-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000010067.1|UniProtKB=W5MVA8 W5MVA8 PTHR24055:SF172 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 9 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 B cell activation#P00010>Jnk#P00402;Ras Pathway#P04393>JNK#P04572;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Huntington disease#P00029>JNK-2#P00799;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;FAS signaling pathway#P00020>JNK#P00615;EGF receptor signaling pathway#P00018>JNK1-3#P00545;Integrin signalling pathway#P00034>Jnk#P00951;FGF signaling pathway#P00021>JNK1-3#P00628;TGF-beta signaling pathway#P00052>JNK#P01284;T cell activation#P00053>Jnk#P01336;Parkinson disease#P00049>SAPK#P01219;Toll receptor signaling pathway#P00054>JNK#P01375;Oxidative stress response#P00046>JNK1/2#P01129;Apoptosis signaling pathway#P00006>JNK#P00274;CCKR signaling map#P06959>MAPK8-10#P07090;Gonadotropin-releasing hormone receptor pathway#P06664>JNK1/2#P06847 LEPOC|Ensembl=ENSLOCG00000010562.1|UniProtKB=W5MX33 W5MX33 PTHR34257:SF3 ADAPTER PROTEIN CIKS E3 UBIQUITIN LIGASE TRAF3IP2 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;humoral immune response#GO:0006959;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005835.1|UniProtKB=W5MF86 W5MF86 PTHR23205:SF0 SPLICING FACTOR 3A SUBUNIT 2 SPLICING FACTOR 3A SUBUNIT 2 spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006521.1|UniProtKB=W5MHN2 W5MHN2 PTHR31859:SF24 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39C multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;embryonic morphogenesis#GO:0048598;animal organ development#GO:0048513;plasma membrane bounded cell projection assembly#GO:0120031;sensory organ development#GO:0007423;developmental process#GO:0032502;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;embryo development#GO:0009790;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;inner ear morphogenesis#GO:0042472;inner ear development#GO:0048839;cell projection assembly#GO:0030031;cellular process#GO:0009987;anatomical structure development#GO:0048856;cilium organization#GO:0044782;ear development#GO:0043583;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;cell projection organization#GO:0030030;animal organ morphogenesis#GO:0009887;sensory organ morphogenesis#GO:0090596;cellular component organization#GO:0016043;cilium assembly#GO:0060271;anatomical structure morphogenesis#GO:0009653 LEPOC|Ensembl=ENSLOCG00000014055.1|UniProtKB=W5N9M5 W5N9M5 PTHR13260:SF0 ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4 ANAPHASE-PROMOTING COMPLEX SUBUNIT 4 protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein K11-linked ubiquitination#GO:0070979;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;organelle lumen#GO:0043233;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000002362.1|UniProtKB=W5M312 W5M312 PTHR24103:SF629 E3 UBIQUITIN-PROTEIN LIGASE TRIM BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 12 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000004624.1|UniProtKB=W5MAY4 W5MAY4 PTHR24028:SF248 CADHERIN-87A PROTOCADHERIN-9 cell adhesion#GO:0007155;cellular process#GO:0009987 synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;cell junction#GO:0030054;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000010993.1|UniProtKB=W5MYN7 W5MYN7 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000008714.1|UniProtKB=W5MQE7 W5MQE7 PTHR10026:SF144 CYCLIN CYCLIN-K molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 regulation of biological process#GO:0050789;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription elongation#GO:0032784;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911 kinase activator#PC00138;kinase modulator#PC00140 Cell cycle#P00013>CdkC#P00489 LEPOC|Ensembl=ENSLOCG00000011221.1|UniProtKB=W5MZI4 W5MZI4 PTHR43294:SF26 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;localization#GO:0051179;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;export from cell#GO:0140352;homeostatic process#GO:0042592;import across plasma membrane#GO:0098739;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000007555.1|UniProtKB=W5MLD5 W5MLD5 PTHR23220:SF9 INTEGRIN ALPHA INTEGRIN ALPHA-6 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;immune system process#GO:0002376;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell migration#GO:0016477;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;signal transduction#GO:0007165;leukocyte migration#GO:0050900;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;integrin complex#GO:0008305 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000016903.1|UniProtKB=W5NJT4 W5NJT4 PTHR23166:SF3 FILAMIN/GPBP-INTERACTING PROTEIN FILAMIN-A-INTERACTING PROTEIN 1 intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;macromolecule localization#GO:0033036 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000010426.1|UniProtKB=W5MWM6 W5MWM6 PTHR14398:SF1 RNA RECOGNITION RRM/RNP DOMAIN RNA-BINDING PROTEIN 27 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010412.1|UniProtKB=W5MWK9 W5MWK9 PTHR24390:SF162 ZINC FINGER PROTEIN FEZ FAMILY ZINC FINGER 2 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000002734.1|UniProtKB=W5M4A7 W5M4A7 PTHR10829:SF25 CORTACTIN AND DREBRIN COACTOSIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament polymerization#GO:0030833;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;actin filament#GO:0005884;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000009151.1|UniProtKB=W5MRZ9 W5MRZ9 PTHR12845:SF8 GUANINE NUCLEOTIDE EXCHANGE FACTOR EPHEXIN-1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000010399.1|UniProtKB=W5MWK4 W5MWK4 PTHR24115:SF472 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3A cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;hydrolase activity#GO:0016787;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544 cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;axonal transport#GO:0098930;anterograde axonal transport#GO:0008089;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000004144.1|UniProtKB=W5M9A2 W5M9A2 PTHR45629:SF17 SNF2/RAD54 FAMILY MEMBER DNA REPAIR AND RECOMBINATION PROTEIN RAD54-LIKE DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fission#GO:0048285;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;homologous recombination#GO:0035825;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000007142.1|UniProtKB=W5MJV1 W5MJV1 PTHR24416:SF295 TYROSINE-PROTEIN KINASE RECEPTOR DISCOIDIN DOMAIN-CONTAINING RECEPTOR 2 molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;binding#GO:0005488;collagen binding#GO:0005518;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of intracellular signal transduction#GO:1902533 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001474.1|UniProtKB=W5M007 W5M007 PTHR10857:SF4 COPINE COPINE-4 phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 response to calcium ion#GO:0051592;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to metal ion#GO:0010038;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000016272.1|UniProtKB=W5NHH6 W5NHH6 PTHR47535:SF9 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 establishment of localization in cell#GO:0051649;nuclear migration#GO:0007097;cellular process#GO:0009987;establishment of organelle localization#GO:0051656;transport#GO:0006810;organelle localization#GO:0051640;intracellular transport#GO:0046907;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 nuclear protein-containing complex#GO:0140513;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane#GO:0016020;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967 LEPOC|Ensembl=ENSLOCG00000005221.1|UniProtKB=W5MD26 W5MD26 PTHR32178:SF8 FAM187 PROTEIN FAM187B immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000014042.1|UniProtKB=W5N9J7 W5N9J7 PTHR11242:SF15 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 9A cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein modification process#GO:0036211;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 membrane#GO:0016020;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004405.1|UniProtKB=W5MA66 W5MA66 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011225.1|UniProtKB=W5MZJ6 W5MZJ6 PTHR10127:SF866 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING TOLLOID-LIKE PROTEIN 2 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;developmental process#GO:0032502;multicellular organism development#GO:0007275;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;regionalization#GO:0003002;gene expression#GO:0010467;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;proteolysis#GO:0006508;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;dorsal/ventral pattern formation#GO:0009953 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000007802.1|UniProtKB=W5MM57 W5MM57 PTHR16485:SF3 MICROFIBRILLAR-ASSOCIATED PROTEIN 2 MICROFIBRILLAR-ASSOCIATED PROTEIN 2 animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;sensory organ development#GO:0007423;developmental process#GO:0032502;multicellular organismal process#GO:0032501;embryo development#GO:0009790;sensory system development#GO:0048880;anatomical structure development#GO:0048856;eye development#GO:0001654;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;visual system development#GO:0150063;anatomical structure morphogenesis#GO:0009653 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;interstitial matrix#GO:0005614;supramolecular complex#GO:0099080;extracellular region#GO:0005576;supramolecular fiber#GO:0099512 LEPOC|Ensembl=ENSLOCG00000000344.1|UniProtKB=W5LW69 W5LW69 PTHR11481:SF64 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;immune system process#GO:0002376;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;immune response#GO:0006955;signal transduction#GO:0007165 plasma membrane#GO:0005886;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005746.1|UniProtKB=W5MEY1 W5MEY1 PTHR22805:SF2 WDR41-RELATED WD REPEAT-CONTAINING PROTEIN 41 LEPOC|Ensembl=ENSLOCG00000002363.1|UniProtKB=W5M310 W5M310 PTHR24300:SF319 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450, FAMILY 2, SUBFAMILY AC, POLYPEPTIDE 1 tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to chemical#GO:0042221;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000014753.1|UniProtKB=W5NC04 W5NC04 PTHR11579:SF19 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 methyltransferase#PC00155;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000004464.1|UniProtKB=W5MAC8 W5MAC8 PTHR16027:SF3 DILUTE DOMAIN-CONTAINING PROTEIN YPR089W RAS-ASSOCIATING AND DILUTE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515 cell motility#GO:0048870;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;stem cell development#GO:0048864;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;cell-substrate adhesion#GO:0031589;stem cell differentiation#GO:0048863;cellular process#GO:0009987;neural crest cell migration#GO:0001755;neural crest cell development#GO:0014032;cell migration#GO:0016477;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;neural crest cell differentiation#GO:0014033;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cellular developmental process#GO:0048869;animal organ development#GO:0048513;mesenchyme development#GO:0060485 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000000518.1|UniProtKB=W5LWR3 W5LWR3 PTHR48071:SF37 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003177.1|UniProtKB=W5M5Y4 W5M5Y4 PTHR24023:SF987 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXIV) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000004035.1|UniProtKB=W5M8W9 W5M8W9 PTHR13930:SF0 S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000003046.1|UniProtKB=W5M5C9 W5M5C9 PTHR10736:SF55 BESTROPHIN BESTROPHIN-4 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000000893.1|UniProtKB=W5LXY5 W5LXY5 PTHR23266:SF396 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-3 binding#GO:0005488;antigen binding#GO:0003823 immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune effector process#GO:0002252;immune system process#GO:0002376;adaptive immune response#GO:0002250;response to stimulus#GO:0050896;immune response#GO:0006955 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000011802.1|UniProtKB=W5N1K3 W5N1K3 PTHR19432:SF37 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000008330.1|UniProtKB=W5MP21 W5MP21 PTHR12385:SF34 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002215.1|UniProtKB=W5M2H7 W5M2H7 PTHR11728:SF7 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE 1-LIKE PROTEIN catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001504.1|UniProtKB=W5M043 W5M043 PTHR15704:SF7 SUPERKILLER 3 PROTEIN-RELATED SUPERKILLER COMPLEX PROTEIN 3 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016934.1|UniProtKB=W5NJX3 W5NJX3 PTHR13293:SF8 AKIRIN-RELATED AKIRIN-2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of RNA metabolic process#GO:0051254;regulation of response to biotic stimulus#GO:0002831;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of response to biotic stimulus#GO:0002833;regulation of gene expression#GO:0010468;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;positive regulation of response to external stimulus#GO:0032103;positive regulation of transcription by RNA polymerase II#GO:0045944 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000005113.1|UniProtKB=W5MCP6 W5MCP6 PTHR46013:SF9 VASCULAR CELL ADHESION MOLECULE 1 B-CELL RECEPTOR CD22-RELATED cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004854.1|UniProtKB=W5MBU5 W5MBU5 PTHR46016:SF4 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF166 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 LEPOC|Ensembl=ENSLOCG00000003193.1|UniProtKB=W5M5W5 W5M5W5 PTHR24341:SF4 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN ENGRAILED-1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 LEPOC|Ensembl=ENSLOCG00000014372.1|UniProtKB=W5NAN6 W5NAN6 PTHR45704:SF13 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE LEPOC|Ensembl=ENSLOCG00000005258.1|UniProtKB=W5MD89 W5MD89 PTHR44006:SF1 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 mRNA splicing#P00058>U5#P01474 LEPOC|Ensembl=ENSLOCG00000000535.1|UniProtKB=W5LWT4 W5LWT4 PTHR11652:SF1 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;ribosome#GO:0005840;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000015563.1|UniProtKB=W5NEU6 W5NEU6 PTHR11949:SF10 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cell surface receptor signaling pathway#GO:0007166;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of nucleobase-containing compound metabolic process#GO:0019219;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;response to peptide#GO:1901652;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000011026.1|UniProtKB=W5MYT7 W5MYT7 PTHR12247:SF79 POLYCOMB GROUP PROTEIN MBT DOMAIN-CONTAINING PROTEIN 1 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000002068.1|UniProtKB=W5M1Z3 W5M1Z3 PTHR15486:SF103 ANCIENT UBIQUITOUS PROTEIN LIPID DROPLET-REGULATING VLDL ASSEMBLY FACTOR AUP1 macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010507.1|UniProtKB=W5MWW9 W5MWW9 PTHR23351:SF4 FOS TRANSCRIPTION FACTOR-RELATED PROTEIN C-FOS DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>c-fos#G06680;Apoptosis signaling pathway#P00006>Fos#P00317;B cell activation#P00010>fos#P00380;Interleukin signaling pathway#P00036>c-fos#P00967;Gonadotropin-releasing hormone receptor pathway#P06664>c-fos#G06894;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>c-fos#P00884;CCKR signaling map#P06959>FOS#G06973;CCKR signaling map#P06959>FOS#G07266;T cell activation#P00053>fos#P01309;CCKR signaling map#P06959>FOS#P07035;Gonadotropin-releasing hormone receptor pathway#P06664>FOS#P06709;Angiogenesis#P00005>c-Fos#P00235;Huntington disease#P00029>Fos protein#P00801;PDGF signaling pathway#P00047>c-fos#P01145 LEPOC|Ensembl=ENSLOCG00000014406.1|UniProtKB=W5NAS2 W5NAS2 PTHR11787:SF3 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR ALPHA molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;transport#GO:0006810 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein-binding activity modulator#PC00095;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000012968.1|UniProtKB=W5N5R3 W5N5R3 PTHR15744:SF2 BLOM7 KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA splice site recognition#GO:0006376;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013751.1|UniProtKB=W5N8J8 W5N8J8 PTHR44974:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000008704.1|UniProtKB=W5MQD7 W5MQD7 PTHR11890:SF23 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-18 RECEPTOR ACCESSORY PROTEIN molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016423.1|UniProtKB=W5NI27 W5NI27 PTHR22970:SF14 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949 LEPOC|Ensembl=ENSLOCG00000005639.1|UniProtKB=W5MEK0 W5MEK0 PTHR11370:SF6 DNA-REPAIR PROTEIN XRCC1 DNA REPAIR PROTEIN XRCC1 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;base-excision repair#GO:0006284;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002621.1|UniProtKB=W5M3X8 W5M3X8 PTHR10281:SF4 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED NEUFERRICIN membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003035.1|UniProtKB=W5M5B2 W5M5B2 PTHR44176:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003375.1|UniProtKB=W5M6J3 W5M6J3 PTHR43981:SF9 ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000016209.1|UniProtKB=W5NH77 W5NH77 PTHR13429:SF7 FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY FERM DOMAIN-CONTAINING PROTEIN 1 molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 LEPOC|Ensembl=ENSLOCG00000000791.1|UniProtKB=W5LXM3 W5LXM3 PTHR11626:SF8 FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE SQUALENE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 organophosphate metabolic process#GO:0019637;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;phospholipid metabolic process#GO:0006644;secondary alcohol metabolic process#GO:1902652;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220 Cholesterol biosynthesis#P00014>Farnesyl-diphosphate farnesyltransferase#P00499 LEPOC|Ensembl=ENSLOCG00000008390.1|UniProtKB=W5MP84 W5MP84 PTHR12612:SF25 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;protein localization to organelle#GO:0033365 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000014235.1|UniProtKB=W5NA71 W5NA71 PTHR10794:SF45 ABHYDROLASE DOMAIN-CONTAINING PROTEIN MONOACYLGLYCEROL LIPASE ABHD2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 fatty acid catabolic process#GO:0009062;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;regulation of biological process#GO:0050789;cellular response to steroid hormone stimulus#GO:0071383;cellular response to lipid#GO:0071396;signal transduction#GO:0007165;lipid catabolic process#GO:0016042;cellular process#GO:0009987;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;response to steroid hormone#GO:0048545;sexual reproduction#GO:0019953;spermatid development#GO:0007286;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;anatomical structure maturation#GO:0071695;steroid hormone receptor signaling pathway#GO:0043401;germ cell development#GO:0007281;cellular response to stimulus#GO:0051716;cell maturation#GO:0048469;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;acylglycerol metabolic process#GO:0006639;neutral lipid catabolic process#GO:0046461;developmental maturation#GO:0021700;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007;hormone-mediated signaling pathway#GO:0009755;oxoacid metabolic process#GO:0043436;spermatid differentiation#GO:0048515;glycerolipid catabolic process#GO:0046503;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;glycerolipid metabolic process#GO:0046486;gamete generation#GO:0007276;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;carboxylic acid metabolic process#GO:0019752;acylglycerol catabolic process#GO:0046464;metabolic process#GO:0008152;response to chemical#GO:0042221;response to lipid#GO:0033993;sperm capacitation#GO:0048240;response to hormone#GO:0009725;cell communication#GO:0007154;catabolic process#GO:0009056;reproductive process#GO:0022414;developmental process involved in reproduction#GO:0003006;carboxylic acid biosynthetic process#GO:0046394;neutral lipid metabolic process#GO:0006638;cellular developmental process#GO:0048869;spermatogenesis#GO:0007283;developmental process#GO:0032502;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;male gamete generation#GO:0048232;fatty acid biosynthetic process#GO:0006633;carboxylic acid catabolic process#GO:0046395 membrane-bounded organelle#GO:0043227;cilium#GO:0005929;9+2 motile cilium#GO:0097729;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;motile cilium#GO:0031514;organelle#GO:0043226;sperm flagellum#GO:0036126;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014314.1|UniProtKB=W5NAG6 W5NAG6 PTHR23147:SF52 SERINE/ARGININE RICH SPLICING FACTOR SERINE AND ARGININE RICH SPLICING FACTOR 7A ISOFORM X1 nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membraneless organelle#GO:0043228 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000016682.1|UniProtKB=W5NJ01 W5NJ01 PTHR12444:SF4 PROTEIN EFR3 HOMOLOG CMP44E PROTEIN EFR3 HOMOLOG B protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;cellular process#GO:0009987;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000005716.1|UniProtKB=W5MEU5 W5MEU5 PTHR11412:SF139 MACROGLOBULIN / COMPLEMENT C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PROTEIN 8 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731;eye development#GO:0001654;sensory organ development#GO:0007423;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;visual system development#GO:0150063;sensory system development#GO:0048880 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;extracellular region#GO:0005576 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000013411.1|UniProtKB=W5N7C7 W5N7C7 NFE2L1 PTHR24411:SF31 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR ENDOPLASMIC RETICULUM MEMBRANE SENSOR NFE2L1 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000016188.1|UniProtKB=W5NH46 W5NH46 PTHR11404:SF6 SUPEROXIDE DISMUTASE 2 SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000007415.1|UniProtKB=W5MKT4 W5MKT4 PTHR47139:SF3 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9 SI:CH73-361P23.3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;regulation of biological process#GO:0050789 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002183.1|UniProtKB=W5M2G4 W5M2G4 PTHR43184:SF9 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A2 phosphate transmembrane transporter activity#GO:0005315;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;inorganic anion transport#GO:0015698;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;phosphate ion transport#GO:0006817;organophosphate ester transport#GO:0015748 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017362.1|UniProtKB=W5NLF8 W5NLF8 PTHR24228:SF55 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G PROTEIN-COUPLED RECEPTOR 75-RELATED transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005886.1|UniProtKB=W5MFF1 W5MFF1 PTHR32193:SF3 REGULATOR OF CELL CYCLE RGCC REGULATOR OF CELL CYCLE RGCC protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;positive regulation of mitotic cell cycle#GO:0045931;cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of cell cycle phase transition#GO:1901987;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;response to transforming growth factor beta#GO:0071559;regulation of immune response#GO:0050776;intracellular signal transduction#GO:0035556;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;transforming growth factor beta receptor signaling pathway#GO:0007179;intracellular signaling cassette#GO:0141124;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell cycle G1/S phase transition#GO:1902808;immune response-activating signaling pathway#GO:0002757;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;response to endogenous stimulus#GO:0009719;regulation of cell cycle#GO:0051726;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of G1/S transition of mitotic cell cycle#GO:2000045;immune system process#GO:0002376;cellular response to growth factor stimulus#GO:0071363;regulation of mitotic cell cycle phase transition#GO:1901990 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000003132.1|UniProtKB=W5M5M7 W5M5M7 PTHR14678:SF2 PROLINE-RICH PROTEIN 35-RELATED PROLINE-RICH PROTEIN 35 LEPOC|Ensembl=ENSLOCG00000007919.1|UniProtKB=W5MMK5 W5MMK5 PTHR11038:SF16 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;mitochondrial transport#GO:0006839;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrial protein import pathway#GO:7770058 membrane-bounded organelle#GO:0043227;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004223.1|UniProtKB=W5M9J0 W5M9J0 PTHR20859:SF55 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON LAMBDA RECEPTOR 1 immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016002.1|UniProtKB=W5NGE7 W5NGE7 PTHR28661:SF3 SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 1 MICROTUBULE NUCLEATION FACTOR SSNA1 plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon development#GO:0061564;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental growth#GO:0048589;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;developmental cell growth#GO:0048588;system development#GO:0048731;anatomical structure development#GO:0048856;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;axon extension#GO:0048675;cellular process#GO:0009987;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;cell growth#GO:0016049;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;neuron differentiation#GO:0030182;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 intracellular organelle#GO:0043229;cilium#GO:0005929;axon#GO:0030424;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membraneless organelle#GO:0043228;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000006825.1|UniProtKB=W5MIP0 W5MIP0 PTHR31612:SF2 MULTIVESICULAR BODY SUBUNIT 12A MULTIVESICULAR BODY SUBUNIT 12A endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;establishment of localization in cell#GO:0051649;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;endosomal transport#GO:0016197;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;regulation of response to stimulus#GO:0048583;transport#GO:0006810;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;localization#GO:0051179;cellular localization#GO:0051641;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;regulation of signaling#GO:0023051 intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cytosol#GO:0005829;ESCRT I complex#GO:0000813;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000000375.1|UniProtKB=W5LWA1 W5LWA1 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014417.1|UniProtKB=W5NAT6 W5NAT6 PTHR31996:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 115 VACUOLAR ATPASE ASSEMBLY PROTEIN VMA22 biological regulation#GO:0065007;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;vacuolar acidification#GO:0007035;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of intracellular pH#GO:0051453 membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;endoplasmic reticulum#GO:0005783;proton-transporting two-sector ATPase complex#GO:0016469;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176 LEPOC|Ensembl=ENSLOCG00000009102.1|UniProtKB=W5MRT5 W5MRT5 PTHR11771:SF161 LIPOXYGENASE ARACHIDONATE 15-LIPOXYGENASE TYPE B oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 icosanoid metabolic process#GO:0006690;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;arachidonate metabolic process#GO:0019369;lipid oxidation#GO:0034440;olefinic compound metabolic process#GO:0120254;oxoacid metabolic process#GO:0043436 oxygenase#PC00177;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011434.1|UniProtKB=W5N091 W5N091 PTHR12708:SF0 DNA POLYMERASE EPSILON SUBUNIT B DNA POLYMERASE EPSILON SUBUNIT 2 response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;DNA-templated DNA replication#GO:0006261;DNA synthesis involved in DNA replication#GO:0090592;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974 epsilon DNA polymerase complex#GO:0008622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694 DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000015208.1|UniProtKB=W5NDK5 W5NDK5 PTHR19308:SF8 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 7, MITOCHONDRIAL LEPOC|Ensembl=ENSLOCG00000002086.1|UniProtKB=W5M235 W5M235 PTHR12845:SF4 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 26 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of actin filament-based process#GO:0032970;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000015779.1|UniProtKB=W5NFL7 W5NFL7 PTHR15715:SF26 CENTROSOMAL PROTEIN OF 170 KDA COILED-COIL DOMAIN-CONTAINING PROTEIN 136 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;sexual reproduction#GO:0019953;spermatid development#GO:0007286;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;regulation of cell communication#GO:0010646;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cellular developmental process#GO:0048869;negative regulation of cellular process#GO:0048523;spermatogenesis#GO:0007283;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;male gamete generation#GO:0048232;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of hippo signaling#GO:0035331;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;spermatid differentiation#GO:0048515;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;acrosome assembly#GO:0001675;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;regulation of hippo signaling#GO:0035330;cellular process involved in reproduction in multicellular organism#GO:0022412;fertilization#GO:0009566;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;negative regulation of signal transduction#GO:0009968;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;single fertilization#GO:0007338;cellular process#GO:0009987 intracellular organelle#GO:0043229;acrosomal vesicle#GO:0001669;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;acrosomal membrane#GO:0002080;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000018247.1|UniProtKB=W5NNY9 W5NNY9 PTHR22752:SF11 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 62 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;signaling receptor complex#GO:0043235;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000011341.1|UniProtKB=W5MZZ4 W5MZZ4 PTHR22803:SF69 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED C-TYPE MANNOSE RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000003938.1|UniProtKB=W5M8L2 W5M8L2 PTHR10877:SF134 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-1-LIKE PROTEIN 2 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803 detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to stimulus#GO:0050896;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000005622.1|UniProtKB=W5MEH8 W5MEH8 PTHR20859:SF55 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON LAMBDA RECEPTOR 1 transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;response to peptide#GO:1901652 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010387.1|UniProtKB=W5MWI0 W5MWI0 PTHR14738:SF29 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 binding#GO:0005488;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA stability#GO:0043488 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000013257.1|UniProtKB=W5N6U3 W5N6U3 PTHR23220:SF73 INTEGRIN ALPHA INTEGRIN ALPHA-IIB signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system development#GO:0048731;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;tube morphogenesis#GO:0035239;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;blood vessel morphogenesis#GO:0048514;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;tube development#GO:0035295;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;integrin#PC00126 Blood coagulation#P00011>GP IIb#P00410;Integrin signalling pathway#P00034>Integrin alpha#P00941 LEPOC|Ensembl=ENSLOCG00000017635.1|UniProtKB=W5NM81 W5NM81 PTHR24369:SF207 ANTIGEN BSP, PUTATIVE-RELATED IG-LIKE DOMAIN-CONTAINING PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011673.1|UniProtKB=W5N135 W5N135 PTHR46365:SF1 COPPER TRANSPORT PROTEIN ATOX1 COPPER TRANSPORT PROTEIN ATOX1 molecular carrier activity#GO:0140104 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000010263.1|UniProtKB=W5MW15 W5MW15 PTHR43658:SF14 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING], MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000002838.1|UniProtKB=W5M4N2 W5M4N2 PTHR46485:SF6 LIM DOMAIN KINASE 1 DUAL SPECIFICITY TESTIS-SPECIFIC PROTEIN KINASE 2 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014326.1|UniProtKB=W5NAI2 W5NAI2 PTHR11471:SF28 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10 signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of apoptotic signaling pathway#GO:2001233;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;positive regulation of canonical NF-kappaB signal transduction#GO:0043123 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000001025.1|UniProtKB=W5LYE7 W5LYE7 PTHR45653:SF6 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 2 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488 syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell differentiation#GO:0030154;cell motility#GO:0048870;cell migration#GO:0016477;muscle structure development#GO:0061061;myoblast fusion#GO:0007520;muscle cell differentiation#GO:0042692;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000016995.1|UniProtKB=W5NK51 W5NK51 PTHR24056:SF570 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 19 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mediator complex#GO:0016592;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009800.1|UniProtKB=W5MUB7 W5MUB7 PTHR14911:SF13 THUMP DOMAIN-CONTAINING TRNA (GUANINE(6)-N(2))-METHYLTRANSFERASE THUMP3 tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000013082.1|UniProtKB=W5N655 W5N655 PTHR45869:SF7 C-REACTIVE PROTEIN-RELATED PENTRAXIN FAMILY MEMBER LEPOC|Ensembl=ENSLOCG00000014988.1|UniProtKB=W5NCU5 W5NCU5 PTHR46973:SF1 GRAM DOMAIN-CONTAINING PROTEIN 2A GRAM DOMAIN-CONTAINING PROTEIN 2A phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of transport#GO:0051049;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane contact site#GO:0044232;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000014270.1|UniProtKB=W5NAA6 W5NAA6 PTHR15917:SF3 FAMILY NOT NAMED INHIBITORY SYNAPTIC FACTOR 1 trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;regulation of biological quality#GO:0065008;chemical synaptic transmission#GO:0007268;regulation of postsynaptic membrane potential#GO:0060078;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission, postsynaptic#GO:0099565;cell surface receptor signaling pathway#GO:0007166;regulation of membrane potential#GO:0042391;system process#GO:0003008;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;postsynapse#GO:0098794;cell junction#GO:0030054;postsynaptic density#GO:0014069 LEPOC|Ensembl=ENSLOCG00000017747.1|UniProtKB=W5NMJ2 W5NMJ2 PTHR11829:SF361 FORKHEAD BOX PROTEIN FORKHEAD BOX D2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000003718.1|UniProtKB=W5M7R0 W5M7R0 PTHR22776:SF28 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN 1 biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007344.1|UniProtKB=W5MKJ4 W5MKJ4 PTHR46257:SF2 TYROSINE-PROTEIN PHOSPHATASE CORKSCREW TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE binding#GO:0005488;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cellular developmental process#GO:0048869;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular process#GO:0009987;developmental process#GO:0032502 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017161.1|UniProtKB=W5NKQ4 W5NKQ4 PTHR23308:SF66 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 KANADAPTIN molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000004273.1|UniProtKB=W5M9Q0 W5M9Q0 PTHR32123:SF10 BICD FAMILY-LIKE CARGO ADAPTER BICD FAMILY-LIKE CARGO ADAPTER 1-RELATED vesicle cytoskeletal trafficking#GO:0099518;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000017871.1|UniProtKB=W5NMW5 W5NMW5 PTHR24249:SF381 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE ASSOCIATED RECEPTOR 14A ISOFORM X1-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000014199.1|UniProtKB=W5NA33 W5NA33 PTHR13843:SF6 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1A tubulin binding#GO:0015631;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 dendrite development#GO:0016358;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of microtubule cytoskeleton organization#GO:0070507;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;neuron projection development#GO:0031175;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of microtubule-based process#GO:0032886;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;cellular developmental process#GO:0048869;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564 cell body#GO:0044297;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuronal cell body#GO:0043025;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;cell junction#GO:0030054;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 LEPOC|Ensembl=ENSLOCG00000006806.1|UniProtKB=W5MIN0 W5MIN0 PTHR45807:SF5 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK1 catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;non-membrane spanning protein tyrosine kinase activity#GO:0004715 defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;cellular developmental process#GO:0048869;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;developmental process#GO:0032502;response to other organism#GO:0051707;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;immune response#GO:0006955;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cytokine-mediated signaling pathway#GO:0019221;cellular response to peptide hormone stimulus#GO:0071375;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;interleukin-2-mediated signaling pathway#GO:0038110;cell surface receptor signaling pathway#GO:0007166;cell surface receptor signaling pathway via STAT#GO:0097696;interleukin-15-mediated signaling pathway#GO:0035723;interleukin-9-mediated signaling pathway#GO:0038113;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;response to type II interferon#GO:0034341;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to stress#GO:0006950;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607;response to peptide#GO:1901652;response to oxygen-containing compound#GO:1901700;type I interferon-mediated signaling pathway#GO:0060337;immune system process#GO:0002376;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 non-receptor tyrosine protein kinase#PC00168 Interferon-gamma signaling pathway#P00035>Jak1#P00953;JAK/STAT signaling pathway#P00038>Jak#P01034;Angiogenesis#P00005>JAK1#P00185;PDGF signaling pathway#P00047>Jak#P01155 LEPOC|Ensembl=ENSLOCG00000016914.1|UniProtKB=W5NJV2 W5NJV2 PTHR28575:SF1 MEIOSIS-SPECIFIC PROTEIN MEI4 MEIOSIS-SPECIFIC PROTEIN MEI4 organelle organization#GO:0006996;meiotic DNA double-strand break formation#GO:0042138;cellular process#GO:0009987;homologous chromosome pairing at meiosis#GO:0007129;oogenesis#GO:0048477;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;DNA metabolic process#GO:0006259;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;male gamete generation#GO:0048232;nucleobase-containing compound metabolic process#GO:0006139;developmental process#GO:0032502;spermatogenesis#GO:0007283;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;meiotic nuclear division#GO:0140013;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;organelle fission#GO:0048285;multicellular organismal reproductive process#GO:0048609 membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;synaptonemal structure#GO:0099086;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;chromosome#GO:0005694;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000001767.1|UniProtKB=W5M0Y4 W5M0Y4 PTHR24232:SF91 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009235.1|UniProtKB=W5MSA9 W5MSA9 PTHR45956:SF3 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000016616.1|UniProtKB=W5NIR5 W5NIR5 PTHR24329:SF362 HOMEOBOX PROTEIN ARISTALESS INTESTINE-SPECIFIC HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cell development#GO:0048468;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000006450.1|UniProtKB=W5MHD1 W5MHD1 PTHR12460:SF40 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 LEPOC|Ensembl=ENSLOCG00000009576.1|UniProtKB=W5MTJ3 W5MTJ3 PTHR24124:SF5 ANKYRIN REPEAT FAMILY A NF-KAPPA-B INHIBITOR ZETA regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002664.1|UniProtKB=W5M426 W5M426 PTHR45828:SF44 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000007098.1|UniProtKB=W5MJN7 W5MJN7 PTHR43690:SF42 NARDILYSIN INSULIN-DEGRADING ENZYME metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 hormone metabolic process#GO:0042445;catabolic process#GO:0009056;biological regulation#GO:0065007;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;peptide catabolic process#GO:0043171;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;regulation of biological quality#GO:0065008;peptide metabolic process#GO:0006518;macromolecule catabolic process#GO:0009057;proteolysis#GO:0006508;metabolic process#GO:0008152;protein catabolic process#GO:0030163 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;peroxisome#GO:0005777;microbody#GO:0042579;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000017803.1|UniProtKB=W5NMP8 W5NMP8 PTHR15462:SF10 SERINE PROTEASE SERINE PROTEASE 23 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000014068.1|UniProtKB=W5N9N3 W5N9N3 PTHR22406:SF4 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM SLAIN MOTIF-CONTAINING PROTEIN 2 protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;positive regulation of cellular component organization#GO:0051130;regulation of microtubule polymerization#GO:0031113;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;microtubule nucleation#GO:0007020;regulation of cellular component biogenesis#GO:0044087;cytoplasmic microtubule organization#GO:0031122;regulation of cellular component organization#GO:0051128;microtubule polymerization#GO:0046785;regulation of microtubule polymerization or depolymerization#GO:0031110;positive regulation of cellular process#GO:0048522;microtubule polymerization or depolymerization#GO:0031109;biological regulation#GO:0065007;positive regulation of protein polymerization#GO:0032273;regulation of microtubule-based process#GO:0032886;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493 microtubule end#GO:1990752;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule plus-end#GO:0035371;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000010243.1|UniProtKB=W5MVZ6 W5MVZ6 PTHR19972:SF14 CALBINDIN CALBINDIN small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axon#GO:0030424;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection#GO:0042995;neuron projection terminus#GO:0044306;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;axon terminus#GO:0043679;cell junction#GO:0030054;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;neuron projection#GO:0043005;presynapse#GO:0098793;nucleus#GO:0005634;cytosol#GO:0005829 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000006154.1|UniProtKB=W5MGC5 W5MGC5 PTHR19850:SF29 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-1 signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234 protein-binding activity modulator#PC00095;G-protein#PC00020;heterotrimeric G-protein#PC00117 Nicotine pharmacodynamics pathway#P06587>GNB#P06591;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;GABA-B receptor II signaling#P05731>Gbeta#P05755;Enkephalin release#P05913>G-Protein (s)#P05977;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;PI3 kinase pathway#P00048>Gbetagamma#P01188;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Wnt signaling pathway#P00057>GBeta#P01457;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;CCKR signaling map#P06959>Gbeta/gamma#P07197;Enkephalin release#P05913>G-Protein (i)#P05974;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710 LEPOC|Ensembl=ENSLOCG00000018327.1|UniProtKB=W5NP69 W5NP69 PTHR13516:SF8 RIBONUCLEASE P SUBUNIT P25 RIBONUCLEASE P PROTEIN SUBUNIT P25-LIKE PROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular protein-containing complex#GO:0140535;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000005685.1|UniProtKB=W5MEQ6 W5MEQ6 PTHR23147:SF133 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 10 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;membraneless organelle#GO:0043228;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000000412.1|UniProtKB=W5LWE3 W5LWE3 PTHR11977:SF33 VILLIN ADVILLIN protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543 regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of actin filament depolymerization#GO:0030834;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000017739.1|UniProtKB=W5NMI4 W5NMI4 PTHR31416:SF1 TRANSMEMBRANE PROTEIN 125 TRANSMEMBRANE PROTEIN 125 LEPOC|Ensembl=ENSLOCG00000006297.1|UniProtKB=W5MGX4 W5MGX4 PTHR10283:SF109 SOLUTE CARRIER FAMILY 13 MEMBER NA(+)_CITRATE COTRANSPORTER transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;dicarboxylic acid transmembrane transporter activity#GO:0005310;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;succinate transmembrane transporter activity#GO:0015141;C4-dicarboxylate transmembrane transporter activity#GO:0015556;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;citrate transmembrane transporter activity#GO:0015137;symporter activity#GO:0015293;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324 dicarboxylic acid transport#GO:0006835;succinate transport#GO:0015744;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;tricarboxylic acid transport#GO:0006842;organic acid transport#GO:0015849;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;citrate transport#GO:0015746 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000006099.1|UniProtKB=W5MG63 W5MG63 PTHR24023:SF861 COLLAGEN ALPHA ACETYLCHOLINESTERASE COLLAGENIC TAIL PEPTIDE structural molecule activity#GO:0005198;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;heparin binding#GO:0008201 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000006804.1|UniProtKB=W5MIM6 W5MIM6 PTHR24412:SF418 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000003346.1|UniProtKB=W5M6E4 W5M6E4 PTHR21630:SF10 VEPH-A/MELTED VENTRICULAR ZONE-EXPRESSED PH DOMAIN-CONTAINING PROTEIN HOMOLOG 1 phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;ion binding#GO:0043167;binding#GO:0005488;phospholipid binding#GO:0005543;anion binding#GO:0043168;small molecule binding#GO:0036094 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000005545.1|UniProtKB=W5ME83 W5ME83 PTHR11215:SF1 METAL DEPENDENT HYDROLASE - RELATED MYG1 EXONUCLEASE hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000003358.1|UniProtKB=W5M6G7 W5M6G7 PTHR11034:SF21 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG4 positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000010686.1|UniProtKB=W5MXI2 W5MXI2 PTHR12736:SF11 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 2 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to alcohol#GO:1905957;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to alcohol#GO:1901419;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of abscisic acid-activated signaling pathway#GO:0009787 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000001381.1|UniProtKB=W5LZL7 W5LZL7 PTHR23101:SF25 RAB GDP/GTP EXCHANGE FACTOR GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1 small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000000286.1|UniProtKB=W5LW05 W5LW05 PTHR19331:SF491 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 cargo receptor activity#GO:0038024 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000002093.1|UniProtKB=W5M230 W5M230 PTHR21677:SF1 CRAMPED PROTEIN PROTEIN CRAMPED-LIKE chromatin binding#GO:0003682;binding#GO:0005488 multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;pattern specification process#GO:0007389;developmental process#GO:0032502 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000000820.1|UniProtKB=W5LXQ7 W5LXQ7 PTHR10652:SF1 ADENYLYL CYCLASE-ASSOCIATED PROTEIN ADENYLYL CYCLASE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;developmental process#GO:0032502;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cell morphogenesis#GO:0000902;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000004968.1|UniProtKB=W5MC67 W5MC67 PTHR24241:SF143 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PYROGLUTAMYLATED RF-AMIDE PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004014.1|UniProtKB=W5M8V3 W5M8V3 PTHR23131:SF6 ENDORIBONUCLEASE LACTB2 ENDORIBONUCLEASE LACTB2 nuclease activity#GO:0004518;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;single-stranded RNA binding#GO:0003727;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 endoribonuclease#PC00094;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010318.1|UniProtKB=J3AMA0 J3AMA0 PTHR16551:SF5 AGOUTI RELATED AGOUTI-RELATED PEPTIDE 2 protein binding#GO:0005515;molecular function activator activity#GO:0140677;hormone activity#GO:0005179;signaling receptor binding#GO:0005102;binding#GO:0005488;neuropeptide hormone activity#GO:0005184;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;neuropeptide receptor binding#GO:0071855;G protein-coupled receptor binding#GO:0001664 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of multicellular organismal process#GO:0051240;feeding behavior#GO:0007631;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000014320.1|UniProtKB=W5NAI1 W5NAI1 PTHR11915:SF425 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-4 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cell junction#GO:0030054;cytoskeleton#GO:0005856;I band#GO:0031674;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 LEPOC|Ensembl=ENSLOCG00000016880.1|UniProtKB=W5NJR1 W5NJR1 PTHR10516:SF25 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4 cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000015362.1|UniProtKB=W5NE50 W5NE50 PTHR13108:SF9 CONDENSIN COMPLEX SUBUNIT 2 CONDENSIN COMPLEX SUBUNIT 2 binding#GO:0005488;chromatin binding#GO:0003682 cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;mitotic cell cycle#GO:0000278;nuclear division#GO:0000280;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;organelle fission#GO:0048285 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;condensin complex#GO:0000796;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694 LEPOC|Ensembl=ENSLOCG00000012471.1|UniProtKB=W5N3Z5 W5N3Z5 PTHR11863:SF241 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000001555.1|UniProtKB=W5M075 W5M075 PTHR47193:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1 voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215 regulation of cell motility#GO:2000145;monoatomic cation transport#GO:0006812;localization#GO:0051179;multicellular organismal reproductive process#GO:0048609;regulation of microtubule-based process#GO:0032886;sexual reproduction#GO:0019953;cell motility#GO:0048870;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;metal ion transport#GO:0030001;developmental process involved in reproduction#GO:0003006;establishment of localization#GO:0051234;flagellated sperm motility#GO:0030317;transport#GO:0006810;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;cilium-dependent cell motility#GO:0060285;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;gamete generation#GO:0007276;regulation of microtubule-based movement#GO:0060632;sperm motility#GO:0097722;regulation of biological process#GO:0050789;calcium ion transport#GO:0006816;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;CatSper complex#GO:0036128;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000015588.1|UniProtKB=W5NEY8 W5NEY8 PTHR43272:SF36 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 6 ISOFORM X1 ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000002111.1|UniProtKB=W5M243 W5M243 PTHR24219:SF6 LIM DOMAIN-CONTAINING PROTEIN JUB WILMS TUMOR PROTEIN 1-INTERACTING PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;regulation of cell communication#GO:0010646;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of translation#GO:0017148;regulation of signaling#GO:0023051;negative regulation of metabolic process#GO:0009892;regulation of hippo signaling#GO:0035330;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;P-body#GO:0000932;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000011254.1|UniProtKB=W5MZL8 W5MZL8 PTHR24064:SF170 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 15 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000009559.1|UniProtKB=W5MTI0 W5MTI0 PTHR16206:SF12 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 1A negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000010681.1|UniProtKB=W5MXH5 W5MXH5 PTHR11588:SF53 TUBULIN TUBULIN ALPHA-4A CHAIN GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;microtubule-based process#GO:0007017;neurogenesis#GO:0022008;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 tubulin#PC00228;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000015324.1|UniProtKB=W5NDZ8 W5NDZ8 PTHR24012:SF692 RNA BINDING PROTEIN CYTOTOXIC GRANULE ASSOCIATED RNA BINDING PROTEIN TIA1 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;single-stranded RNA binding#GO:0003727;mRNA binding#GO:0003729;binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;nucleus#GO:0005634;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015786.1|UniProtKB=W5NFM3 W5NFM3 PTHR16777:SF2 PROTEIN ECT2 PROTEIN ECT2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;cytokinesis#GO:0000910;mitotic cell cycle process#GO:1903047;cytoskeleton-dependent cytokinesis#GO:0061640 cell cortex#GO:0005938;nucleus#GO:0005634;cell periphery#GO:0071944;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000000745.1|UniProtKB=W5LXH0 W5LXH0 PTHR11422:SF16 T-CELL SURFACE GLYCOPROTEIN CD4 DIVERSE IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 3.3 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005424.1|UniProtKB=W5MDT2 W5MDT2 PTHR46484:SF1 SI:CH211-171H4.5-RELATED B-CELL RECEPTOR CD22-RELATED LEPOC|Ensembl=ENSLOCG00000001818.1|UniProtKB=W5M146 W5M146 PTHR10739:SF20 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE B nucleotidyltransferase activity#GO:0016779;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylcholine binding#GO:0031210;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;lipid binding#GO:0008289 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000013925.1|UniProtKB=W5N956 W5N956 PTHR45629:SF13 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;DNA translocase activity#GO:0015616;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 damaged DNA-binding protein#PC00086 LEPOC|Ensembl=ENSLOCG00000015842.1|UniProtKB=W5NFU3 W5NFU3 PTHR15117:SF9 ATAXIN 7 RELATED ATAXIN-7-LIKE PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 LEPOC|Ensembl=ENSLOCG00000006137.1|UniProtKB=W5MGA7 W5MGA7 PTHR46472:SF1 NUCLEOREDOXIN NUCLEOREDOXIN oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036 negative regulation of biological process#GO:0048519;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;negative regulation of protein ubiquitination#GO:0031397;regulation of signaling#GO:0023051;regulation of post-translational protein modification#GO:1901873;negative regulation of cell communication#GO:0010648;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of protein ubiquitination#GO:0031396;regulation of response to stimulus#GO:0048583;regulation of protein modification process#GO:0031399 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000006526.1|UniProtKB=W5MHM3 W5MHM3 PTHR10687:SF11 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 4 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;exocytosis#GO:0006887;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network membrane#GO:0032588;vesicle membrane#GO:0012506;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000005836.1|UniProtKB=W5MFB0 W5MFB0 PTHR11010:SF127 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE multicellular organism development#GO:0007275;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;developmental process#GO:0032502;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;tube development#GO:0035295;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;response to stress#GO:0006950;response to wounding#GO:0009611;anatomical structure development#GO:0048856;angiogenesis#GO:0001525;regulation of cell motility#GO:2000145;wound healing#GO:0042060;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;tube morphogenesis#GO:0035239;blood vessel development#GO:0001568;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000007019.1|UniProtKB=W5MJD5 W5MJD5 PTHR45946:SF3 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-A1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000010250.1|UniProtKB=W5MVY3 W5MVY3 PTHR15076:SF15 CD99/MIC2 PROTEIN RELATED CD99 ANTIGEN immune system process#GO:0002376;mononuclear cell migration#GO:0071674;cell adhesion#GO:0007155;regulation of cell motility#GO:2000145;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;regulation of leukocyte migration#GO:0002685;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of immune system process#GO:0002682;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;positive regulation of locomotion#GO:0040017;cell-cell adhesion#GO:0098609;lymphocyte migration#GO:0072676;positive regulation of immune system process#GO:0002684;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell migration#GO:0030335;cellular process#GO:0009987;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;homotypic cell-cell adhesion#GO:0034109 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000014365.1|UniProtKB=W5NAN1 W5NAN1 PTHR45832:SF9 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517 LEPOC|Ensembl=ENSLOCG00000015640.1|UniProtKB=W5NF46 W5NF46 PTHR42796:SF4 FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED OXALOACETATE TAUTOMERASE FAHD2A, MITOCHONDRIAL hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000010049.1|UniProtKB=W5MV83 W5MV83 PTHR11683:SF10 MYELIN PROTEOLIPID NEURONAL MEMBRANE GLYCOPROTEIN M6-B structural molecule activity#GO:0005198 multicellular organismal process#GO:0032501;oligodendrocyte differentiation#GO:0048709;glial cell differentiation#GO:0010001;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;neuron projection development#GO:0031175;axon development#GO:0061564;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;gliogenesis#GO:0042063;myelination#GO:0042552;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;myelin sheath#GO:0043209;plasma membrane#GO:0005886 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000017637.1|UniProtKB=W5NM83 W5NM83 PTHR22750:SF52 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE-1-PHOSPHATE RECEPTOR 3A transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017931.1|UniProtKB=W5NN25 W5NN25 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008;detection of chemical stimulus#GO:0009593;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013677.1|UniProtKB=W5N8D1 W5N8D1 PTHR10857:SF112 COPINE COPINE-9 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 cellular response to chemical stimulus#GO:0070887;response to metal ion#GO:0010038;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to calcium ion#GO:0051592;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000014018.1|UniProtKB=W5N9H9 W5N9H9 PTHR32022:SF10 D-GLUTAMATE CYCLASE, MITOCHONDRIAL D-GLUTAMATE CYCLASE, MITOCHONDRIAL cyclase activity#GO:0009975;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520 lyase#PC00144;cyclase#PC00079 LEPOC|Ensembl=ENSLOCG00000002457.1|UniProtKB=W5M3D5 W5M3D5 PTHR24345:SF42 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;endomembrane system organization#GO:0010256;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of G1/S transition of mitotic cell cycle#GO:2000045;cellular response to stress#GO:0033554;regulation of mitotic cell cycle phase transition#GO:1901990;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;microtubule cytoskeleton organization involved in mitosis#GO:1902850;Golgi organization#GO:0007030;cellular response to stimulus#GO:0051716;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of cell cycle G1/S phase transition#GO:1902806;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;intracellular signal transduction#GO:0035556 membraneless organelle#GO:0043228;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017679.1|UniProtKB=W5NMC5 W5NMC5 PTHR16433:SF0 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;mannosyltransferase complex#GO:0031501;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000006689.1|UniProtKB=W5MI67 W5MI67 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED signaling receptor activity#GO:0038023;pattern recognition receptor activity#GO:0038187;carbohydrate binding#GO:0030246;molecular transducer activity#GO:0060089;binding#GO:0005488 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008830.1|UniProtKB=W5MQT5 W5MQT5 PTHR10332:SF17 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 3 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001013.1|UniProtKB=W5LYD7 W5LYD7 PTHR11949:SF7 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 8 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000003256.1|UniProtKB=W5M638 W5M638 PTHR19370:SF184 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE-LIKE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010833.1|UniProtKB=W5MY17 W5MY17 PTHR12490:SF4 GSK3B-INTERACTING PROTEIN GSK3B-INTERACTING PROTEIN protein kinase A binding#GO:0051018;binding#GO:0005488;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000017431.1|UniProtKB=W5NLM7 W5NLM7 PTHR12002:SF225 CLAUDIN CLAUDIN cell-cell junction assembly#GO:0007043;transport#GO:0006810;cell-cell junction organization#GO:0045216;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;paracellular transport#GO:0160184;cellular process#GO:0009987;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cell junction organization#GO:0034330;cellular component assembly#GO:0022607 tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000007970.1|UniProtKB=W5MMT0 W5MMT0 PTHR11616:SF318 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;symporter activity#GO:0015293 sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;establishment of localization#GO:0051234;import into cell#GO:0098657 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000000462.1|UniProtKB=W5LWJ7 W5LWJ7 PTHR23411:SF36 TAPASIN IMMUNOGLOBULIN KAPPA CONSTANT immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000005442.1|UniProtKB=W5MDU6 W5MDU6 PTHR24106:SF286 NACHT, LRR AND CARD DOMAINS-CONTAINING NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 3 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000014994.1|UniProtKB=W5NCV4 W5NCV4 PTHR33768:SF6 MIP11318P SI:CH211-284K5.2 LEPOC|Ensembl=ENSLOCG00000009317.1|UniProtKB=W5MSK8 W5MSK8 IL12B PTHR48485:SF4 INTERLEUKIN-12 SUBUNIT BETA-RELATED INTERLEUKIN-12 SUBUNIT BETA receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;growth factor receptor binding#GO:0070851;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine binding#GO:0019955;cytokine activity#GO:0005125;binding#GO:0005488;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;signal transduction#GO:0007165;response to peptide#GO:1901652;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392 LEPOC|Ensembl=ENSLOCG00000002406.1|UniProtKB=W5M379 W5M379 PTHR12425:SF4 SYNEMBRYN CHAPERONE RIC-8A binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004064.1|UniProtKB=W5M905 W5M905 PTHR13026:SF0 NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52 RIBOSOMAL RNA PROCESSING 1B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000004438.1|UniProtKB=W5MAC6 W5MAC6 PTHR24253:SF70 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 5 serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012236.1|UniProtKB=W5N342 W5N342 PTHR43908:SF4 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY B MEMBER 14 heat shock protein binding#GO:0031072;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;cellular response to misfolded protein#GO:0071218;metabolic process#GO:0008152;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to misfolded protein#GO:0051788;protein metabolic process#GO:0019538;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008659.1|UniProtKB=W5MQ74 W5MQ74 PTHR12141:SF3 ARFAPTIN-RELATED ARFAPTIN-2 molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;trans-Golgi network membrane#GO:0032588;organelle#GO:0043226;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 vesicle coat protein#PC00235 Huntington disease#P00029>Arfaptin-2#P00793 LEPOC|Ensembl=ENSLOCG00000001167.1|UniProtKB=W5LYX2 W5LYX2 PTHR11590:SF6 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000002978.1|UniProtKB=W5M550 W5M550 PTHR14167:SF115 SH3 DOMAIN-CONTAINING OSTEOCLAST-STIMULATING FACTOR 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012591.1|UniProtKB=W5N4E5 W5N4E5 PTHR21562:SF7 NOTUM-RELATED PALMITOLEOYL-PROTEIN CARBOXYLESTERASE NOTUM LEPOC|Ensembl=ENSLOCG00000001274.1|UniProtKB=W5LZ89 W5LZ89 PTHR32017:SF3 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 chromosome segregation#GO:0007059;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;outer kinetochore#GO:0000940;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;supramolecular fiber#GO:0099512;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013249.1|UniProtKB=W5N6R7 W5N6R7 PTHR46212:SF3 PEFLIN PROGRAMMED CELL DEATH PROTEIN 6 LEPOC|Ensembl=ENSLOCG00000006215.1|UniProtKB=W5MGK4 W5MGK4 PTHR11055:SF16 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;sulfur compound metabolic process#GO:0006790;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167 LEPOC|Ensembl=ENSLOCG00000005219.1|UniProtKB=W5MD24 W5MD24 PTHR11579:SF2 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 2 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000005055.1|UniProtKB=W5MCH7 W5MCH7 PTHR12688:SF1 DYNEIN LIGHT INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 LIGHT INTERMEDIATE CHAIN 2 protein binding#GO:0005515;binding#GO:0005488 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule-based movement#GO:0007018;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;dynein complex#GO:0030286;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasmic dynein complex#GO:0005868;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;centrosome#GO:0005813;microtubule organizing center#GO:0005815 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 LEPOC|Ensembl=ENSLOCG00000018278.1|UniProtKB=W5NP20 W5NP20 PTHR20855:SF41 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR ALPHA signaling receptor activity#GO:0038023;steroid binding#GO:0005496;lipid binding#GO:0008289;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 response to lipid#GO:0033993;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to steroid hormone#GO:0048545;response to hormone#GO:0009725;response to endogenous stimulus#GO:0009719 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005481.1|UniProtKB=W5ME01 W5ME01 PTHR24012:SF728 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 5 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000014392.1|UniProtKB=W5NAR0 W5NAR0 PTHR31428:SF4 RGM DOMAIN FAMILY MEMBER DRAG-1 REPULSIVE GUIDANCE MOLECULE A coreceptor activity#GO:0015026;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000006841.1|UniProtKB=W5MIR5 W5MIR5 PTHR11850:SF98 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 4 sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell development#GO:0048468;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;eye development#GO:0001654;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790;nervous system development#GO:0007399;head development#GO:0060322;sensory system development#GO:0048880;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryonic organ development#GO:0048568;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000001021.1|UniProtKB=W5LYD8 W5LYD8 PTHR34605:SF3 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN MUCIN-2-LIKE ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000009612.1|UniProtKB=W5MTN6 W5MTN6 PTHR24253:SF194 TRANSMEMBRANE PROTEASE SERINE ENTEROPEPTIDASE peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000015887.1|UniProtKB=W5NG09 W5NG09 PTHR48019:SF168 SERUM RESPONSE FACTOR HOMOLOG SERUM RESPONSE FACTOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;MADS box transcription factor#PC00250 PDGF signaling pathway#P00047>SRF#P01165;CCKR signaling map#P06959>SRF#P07181;PDGF signaling pathway#P00047>c-fos#P01145;Interleukin signaling pathway#P00036>SRF#P00987;Ras Pathway#P04393>SRF#P04561;p38 MAPK pathway#P05918>SRF#P06025;Gonadotropin-releasing hormone receptor pathway#P06664>SRF#P06811 LEPOC|Ensembl=ENSLOCG00000011659.1|UniProtKB=W5N122 W5N122 PTHR12697:SF20 PBS LYASE HEAT-LIKE PROTEIN HEAT REPEAT-CONTAINING PROTEIN 4 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000017233.1|UniProtKB=W5NL06 W5NL06 PTHR22593:SF2 TRANSMEMBRANE PROTEIN 18 TRANSMEMBRANE PROTEIN 18 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane#GO:0016020;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;nuclear membrane#GO:0031965;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011990.1|UniProtKB=W5N290 W5N290 PTHR45638:SF9 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ALPHA-1 anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;purine ribonucleotide binding#GO:0032555;monoatomic ion channel activity#GO:0005216 monoatomic ion transport#GO:0006811;system process#GO:0003008;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;multicellular organismal process#GO:0032501;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ligand-gated ion channel#PC00141;ion channel#PC00133 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 LEPOC|Ensembl=ENSLOCG00000002882.1|UniProtKB=W5M4S9 W5M4S9 PTHR21580:SF21 SHIPPO-1-RELATED O(6)-METHYLGUANINE-INDUCED APOPTOSIS 2 cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915;organelle organization#GO:0006996;programmed cell death#GO:0012501;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;apoptotic mitochondrial changes#GO:0008637;regulation of membrane permeability#GO:0090559;regulation of biological quality#GO:0065008;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000015313.1|UniProtKB=W5NDY3 W5NDY3 PTHR12268:SF16 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN-RELATED PROTEIN 2 cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000015899.1|UniProtKB=W5NG20 W5NG20 PTHR13964:SF24 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4B nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000005296.1|UniProtKB=W5MDB9 W5MDB9 PTHR12478:SF7 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 DNA DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN protein binding#GO:0005515;binding#GO:0005488 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;response to hypoxia#GO:0001666;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;programmed cell death#GO:0012501;response to decreased oxygen levels#GO:0036293;negative regulation of biological process#GO:0048519;response to oxygen levels#GO:0070482;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007 LEPOC|Ensembl=ENSLOCG00000007048.1|UniProtKB=W5MJH9 W5MJH9 PTHR19353:SF57 FATTY ACID DESATURASE 2 ACYL-COA (8-3)-DESATURASE catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000009801.1|UniProtKB=W5MUB5 W5MUB5 PTHR13738:SF9 TROPONIN I TROPONIN I, SLOW SKELETAL MUSCLE protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 nervous system process#GO:0050877;neuromuscular process#GO:0050905;cardiac muscle contraction#GO:0060048;muscle contraction#GO:0006936;circulatory system process#GO:0003013;system process#GO:0003008;heart contraction#GO:0060047;heart process#GO:0003015;muscle system process#GO:0003012;striated muscle contraction#GO:0006941;skeletal muscle contraction#GO:0003009;multicellular organismal process#GO:0032501;blood circulation#GO:0008015 cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000016306.1|UniProtKB=W5NHL8 W5NHL8 PTHR14168:SF7 TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER EPITHELIAL CELL ADHESION MOLECULE cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cell-cell junction#GO:0005911;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;extracellular region#GO:0005576;apical junction complex#GO:0043296 LEPOC|Ensembl=ENSLOCG00000014098.1|UniProtKB=W5N9S9 W5N9S9 PTHR10730:SF7 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER MULTIFUNCTIONAL PROCOLLAGEN LYSINE HYDROXYLASE AND GLYCOSYLTRANSFERASE LH3 glucosyltransferase activity#GO:0046527;dioxygenase activity#GO:0051213;glycosyltransferase activity#GO:0016757;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;collagen fibril organization#GO:0030199;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012979.1|UniProtKB=W5N5S7 W5N5S7 PTHR13767:SF2 TRNA-PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE TRUB1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;tRNA modification#GO:0006400;pseudouridine synthesis#GO:0001522;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 isomerase#PC00135;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000013793.1|UniProtKB=W5N8Q1 W5N8Q1 PTHR23064:SF47 TROPONIN TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cytoskeletal protein binding#GO:0008092 circulatory system process#GO:0003013;nervous system process#GO:0050877;muscle contraction#GO:0006936;neuromuscular process#GO:0050905;cardiac muscle contraction#GO:0060048;heart contraction#GO:0060047;system process#GO:0003008;heart process#GO:0003015;muscle system process#GO:0003012;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941 cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000013723.1|UniProtKB=W5N8G4 W5N8G4 PTHR22437:SF2 WINGED HELIX DOMAIN-CONTAINING PROTEIN STORKHEAD-BOX PROTEIN 2 transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014014.1|UniProtKB=W5N9G4 W5N9G4 PTHR11595:SF59 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER EF-HAND AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000017960.1|UniProtKB=W5NN54 W5NN54 PTHR46468:SF1 SENTRIN-SPECIFIC PROTEASE 8 SENTRIN-SPECIFIC PROTEASE 8 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000002434.1|UniProtKB=W5M3A0 W5M3A0 PTHR44145:SF6 DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000018156.1|UniProtKB=W5NNP8 W5NNP8 PTHR45961:SF5 IP21249P DUAL SPECIFICITY PROTEIN PHOSPHATASE 14 hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 Oxidative stress response#P00046>MKP5#P01131 LEPOC|Ensembl=ENSLOCG00000010722.1|UniProtKB=W5MXM9 W5MXM9 PTHR11534:SF5 MYOGENIC FACTOR MYOGENIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;tissue development#GO:0009888;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;skeletal muscle tissue development#GO:0007519;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of macromolecule metabolic process#GO:0060255;animal organ development#GO:0048513;positive regulation of cell differentiation#GO:0045597;striated muscle tissue development#GO:0014706;positive regulation of transcription by RNA polymerase II#GO:0045944;muscle organ development#GO:0007517;regulation of multicellular organismal process#GO:0051239;positive regulation of cell development#GO:0010720;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000017357.1|UniProtKB=W5NLF3 W5NLF3 PTHR31410:SF1 TRANSMEMBRANE PROTEIN 246 GPI-N-ACETYLGALACTOSAMINE TRANSFERASE PGAP4 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474 intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000012183.1|UniProtKB=W5N2W9 W5N2W9 RNF125 PTHR46016:SF4 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF166 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000001318.1|UniProtKB=W5LZE3 W5LZE3 PTHR13832:SF535 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1E catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of actin filament bundle assembly#GO:0032231;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;cell communication#GO:0007154;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament-based process#GO:0032970;positive regulation of actin filament bundle assembly#GO:0032233 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000008065.1|UniProtKB=W5MN34 W5MN34 PTHR11210:SF60 RING BOX RING-BOX PROTEIN 2 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;Cul5-RING ubiquitin ligase complex#GO:0031466;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000017700.1|UniProtKB=W5NME6 W5NME6 PTHR22752:SF3 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 135 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004275.1|UniProtKB=W5M9S3 W5M9S3 PTHR10694:SF119 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4A histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 LEPOC|Ensembl=ENSLOCG00000015708.1|UniProtKB=W5NFC8 W5NFC8 PTHR15298:SF17 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000001980.1|UniProtKB=W5M1N2 W5M1N2 PTHR28611:SF1 NORRIN NORRIN G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell surface receptor signaling pathway#GO:0007166;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;positive regulation of RNA metabolic process#GO:0051254;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 LEPOC|Ensembl=ENSLOCG00000003791.1|UniProtKB=W5M834 W5M834 PTHR23235:SF109 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002973.1|UniProtKB=W5M543 W5M543 PTHR24061:SF418 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000917.1|UniProtKB=W5LY16 W5LY16 PTHR14819:SF9 GTP-BINDING UP-REGULATOR OF CELL PROLIFERATION-LIKE LEPOC|Ensembl=ENSLOCG00000014123.1|UniProtKB=W5N9U2 W5N9U2 PTHR11138:SF5 METHIONYL-TRNA FORMYLTRANSFERASE METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000016251.1|UniProtKB=W5NHD1 W5NHD1 PTHR48439:SF1 HEMIMETHYLATED DNA-BINDING DOMAIN-CONTAINING PROTEIN HEMIMETHYLATED DNA-BINDING DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000017725.1|UniProtKB=W5NMH0 W5NMH0 PTHR13675:SF1 LYR MOTIF-CONTAINING PROTEIN 2 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex II assembly#GO:0034553;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000006314.1|UniProtKB=W5MGW2 W5MGW2 PTHR10104:SF20 STATHMIN STATHMIN DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;neuron development#GO:0048666;cellular component disassembly#GO:0022411;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;protein depolymerization#GO:0051261;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;microtubule polymerization or depolymerization#GO:0031109;neurogenesis#GO:0022008;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular developmental process#GO:0048869;developmental process#GO:0032502;protein-containing complex disassembly#GO:0032984;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;system development#GO:0048731;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;regulation of microtubule-based process#GO:0032886 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000000212.1|UniProtKB=W5LVS9 W5LVS9 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000005480.1|UniProtKB=W5ME00 W5ME00 PTHR10283:SF139 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000005697.1|UniProtKB=W5MER6 W5MER6 PTHR12436:SF38 80 KDA MCM3-ASSOCIATED PROTEIN SAC3 DOMAIN-CONTAINING PROTEIN 1 nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;spindle organization#GO:0007051;cell cycle#GO:0007049;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;organelle assembly#GO:0070925;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;metabolic process#GO:0008152;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002786.1|UniProtKB=W5M4I3 W5M4I3 PTHR42985:SF50 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SLC5A5 PROTEIN symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017423.1|UniProtKB=W5NLL9 W5NLL9 PTHR17149:SF3 NUCLEAR PROTEIN 1 AND 2 NUCLEAR PROTEIN 2 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cell cycle#GO:0045786;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cell population proliferation#GO:0008285;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006620.1|UniProtKB=W5MHY4 W5MHY4 PTHR13523:SF4 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 10, MITOCHONDRIAL mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 mitochondrion#GO:0005739;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010078.1|UniProtKB=W5MVB9 W5MVB9 PTHR28450:SF1 FANCONI ANEMIA GROUP B PROTEIN FANCONI ANEMIA GROUP B PROTEIN DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;negative regulation of double-strand break repair via homologous recombination#GO:2000042;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular response to stress#GO:0080135;negative regulation of biological process#GO:0048519;double-strand break repair via homologous recombination#GO:0000724;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of double-strand break repair via homologous recombination#GO:0010569;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;DNA repair#GO:0006281;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;regulation of metabolic process#GO:0019222;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;negative regulation of DNA metabolic process#GO:0051053;positive regulation of DNA repair#GO:0045739;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;recombinational repair#GO:0000725;regulation of double-strand break repair#GO:2000779;positive regulation of DNA metabolic process#GO:0051054;negative regulation of DNA recombination#GO:0045910;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of double-strand break repair#GO:2000781 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Fanconi anaemia nuclear complex#GO:0043240;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000013931.1|UniProtKB=W5N972 W5N972 PTHR13619:SF0 PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;phosphatidylglycerol biosynthetic process#GO:0006655;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000002416.1|UniProtKB=W5M377 W5M377 PTHR24073:SF528 DRAB5-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 22 HOMOLOG catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017604.1|UniProtKB=W5NM50 W5NM50 PTHR24031:SF421 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX28-RELATED protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;mitochondrial large ribosomal subunit assembly#GO:1902775;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;protein-RNA complex assembly#GO:0022618;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;cellular component assembly#GO:0022607;mitochondrial ribosome assembly#GO:0061668;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000012656.1|UniProtKB=W5N4M6 W5N4M6 PTHR16017:SF0 GASTRULATION DEFECTIVE PROTEIN 1-RELATED WD REPEAT-CONTAINING PROTEIN 70 site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000002546.1|UniProtKB=W5M3P7 W5M3P7 PTHR12634:SF12 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 3 enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000006444.1|UniProtKB=W5MHD9 W5MHD9 PTHR19277:SF122 PENTRAXIN PENTRAXIN-4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013286.1|UniProtKB=W5N6V9 W5N6V9 PTHR23353:SF34 RAB-GAP/TBC-RELATED TBC1 DOMAIN FAMILY MEMBER 24 GTPase-activating protein#PC00257 N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036 LEPOC|Ensembl=ENSLOCG00000002914.1|UniProtKB=W5M4W6 W5M4W6 PTHR45917:SF14 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 1A-RELATED ion channel regulator activity#GO:0099106;calcium channel regulator activity#GO:0005246;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 response to external stimulus#GO:0009605;system process#GO:0003008;cellular process#GO:0009987;response to radiation#GO:0009314;signal transduction#GO:0007165;detection of stimulus#GO:0051606;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;sensory perception of light stimulus#GO:0050953;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;visual perception#GO:0007601;response to stimulus#GO:0050896 LEPOC|Ensembl=ENSLOCG00000000185.1|UniProtKB=W5LVQ0 W5LVQ0 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000002462.1|UniProtKB=W5M3F3 W5M3F3 PTHR10807:SF52 MYOTUBULARIN-RELATED MYOTUBULARIN RELATED PROTEIN 9 LIKE, PSEUDO catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;protein phosphatase binding#GO:0019903;binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;hydrolase activity#GO:0016787;protein binding#GO:0005515 lipid modification#GO:0030258;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;dephosphorylation#GO:0016311;negative regulation of catabolic process#GO:0009895;phosphatidylinositol dephosphorylation#GO:0046856;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;phospholipid metabolic process#GO:0006644;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000004130.1|UniProtKB=W5M991 W5M991 PTHR45876:SF6 FI04035P RHO GTPASE-ACTIVATING PROTEIN 39 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000011561.1|UniProtKB=W5N0P7 W5N0P7 PTHR10502:SF239 ANNEXIN ANNEXIN A7 ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289 vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000013412.1|UniProtKB=W5N7D4 W5N7D4 PTHR15083:SF0 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000000114.1|UniProtKB=W5LVH1 W5LVH1 PTHR14241:SF1 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 LEPOC|Ensembl=ENSLOCG00000015068.1|UniProtKB=W5ND34 W5ND34 PTHR23412:SF14 STEREOCILIN RELATED STEREOCILIN-RELATED cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155 cluster of actin-based cell projections#GO:0098862;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;stereocilium#GO:0032420;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cell surface#GO:0009986;neuron projection#GO:0043005 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000008792.1|UniProtKB=W5MQQ6 W5MQQ6 PTHR31613:SF2 AUGURIN AUGURIN multicellular organism development#GO:0007275;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nervous system development#GO:0007399;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;animal gross anatomical part developmental process#GO:0160108;modification-dependent macromolecule catabolic process#GO:0043632;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;central nervous system development#GO:0007417;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;developmental process#GO:0032502;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;system development#GO:0048731;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006652.1|UniProtKB=W5MI25 W5MI25 PTHR11910:SF1 ATP SYNTHASE DELTA CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT OSCP, MITOCHONDRIAL monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013120.1|UniProtKB=W5N6A2 W5N6A2 PTHR21646:SF24 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 19 cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000013772.1|UniProtKB=W5N8M3 W5N8M3 PTHR15031:SF8 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 1 ISOFORM X1 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017191.1|UniProtKB=W5NKT7 W5NKT7 PTHR47059:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 32 TETRATRICOPEPTIDE REPEAT PROTEIN 32 LEPOC|Ensembl=ENSLOCG00000003525.1|UniProtKB=W5M726 W5M726 PTHR22983:SF7 PROTEIN KINASE RELATED SERINE_THREONINE-PROTEIN KINASE 36 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Hedgehog signaling pathway#P00025>Fused#P00686 LEPOC|Ensembl=ENSLOCG00000010911.1|UniProtKB=W5MYD6 W5MYD6 PTHR11036:SF27 SEMAPHORIN SEMAPHORIN-3F receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677 animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;mesenchymal cell differentiation#GO:0048762;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;neural crest cell differentiation#GO:0014033;taxis#GO:0042330;response to chemical#GO:0042221;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;neural crest cell migration#GO:0001755;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;mesenchyme development#GO:0060485;neurogenesis#GO:0022008;response to external stimulus#GO:0009605;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neural crest cell development#GO:0014032;cell migration#GO:0016477;tissue development#GO:0009888;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;stem cell development#GO:0048864;chemotaxis#GO:0006935;cell motility#GO:0048870;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000012709.1|UniProtKB=W5N4S6 W5N4S6 PTHR18849:SF21 LEUCINE RICH REPEAT PROTEIN DYNEIN AXONEMAL ASSEMBLY FACTOR 11 axoneme assembly#GO:0035082;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;outer dynein arm assembly#GO:0036158;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000015000.1|UniProtKB=W5NCW0 W5NCW0 PTHR11071:SF477 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000001877.1|UniProtKB=W5M1D2 W5M1D2 PTHR24012:SF365 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 4 mRNA 3'-UTR binding#GO:0003730;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143;binding#GO:0005488 post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010365.1|UniProtKB=W5MWE0 W5MWE0 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000008674.1|UniProtKB=W5MQ87 W5MQ87 PTHR22802:SF475 C-TYPE LECTIN SUPERFAMILY MEMBER CD302 ANTIGEN binding#GO:0005488;signaling receptor activity#GO:0038023;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000014791.1|UniProtKB=W5NC65 W5NC65 PTHR13720:SF50 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000001675.1|UniProtKB=W5M0R5 W5M0R5 PTHR24543:SF302 MULTICOPPER OXIDASE-RELATED COAGULATION FACTOR V biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;blood circulation#GO:0008015;coagulation#GO:0050817;hemostasis#GO:0007599;response to wounding#GO:0009611;response to stress#GO:0006950;wound healing#GO:0042060;regulation of biological quality#GO:0065008;blood coagulation#GO:0007596;system process#GO:0003008;circulatory system process#GO:0003013 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708 oxidoreductase#PC00176 Blood coagulation#P00011>FVa#P00435;Blood coagulation#P00011>FV#P00432 LEPOC|Ensembl=ENSLOCG00000011408.1|UniProtKB=W5N072 W5N072 PTHR13219:SF6 TRANSMEMBRANE PROTEIN 94 TRANSMEMBRANE PROTEIN 94 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;magnesium ion transmembrane transporter activity#GO:0015095 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;magnesium ion transport#GO:0015693;intracellular transport#GO:0046907;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular localization#GO:0051641 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000014797.1|UniProtKB=W5NCA6 W5NCA6 PTHR11254:SF446 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HUWE1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;cellular response to stimulus#GO:0051716;Golgi organization#GO:0007030;modification-dependent protein catabolic process#GO:0019941;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;response to stress#GO:0006950;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000010024.1|UniProtKB=W5MV43 W5MV43 PTHR11860:SF120 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 5-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014216.1|UniProtKB=W5NA51 W5NA51 PTHR14113:SF1 PICCOLO/BASSOON PROTEIN BASSOON structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;developmental process#GO:0032502;synapse assembly#GO:0007416;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;protein localization to cell junction#GO:1902414;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;presynaptic active zone#GO:0048786;cell junction#GO:0030054;cell periphery#GO:0071944;presynapse#GO:0098793;neuron projection#GO:0043005;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;glutamatergic synapse#GO:0098978;axon#GO:0030424;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;plasma membrane bounded cell projection#GO:0120025;GABA-ergic synapse#GO:0098982;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000010382.1|UniProtKB=W5MWG4 W5MWG4 PTHR24264:SF43 TRYPSIN-RELATED HEPATOCYTE GROWTH FACTOR ACTIVATOR SERINE PROTEASE catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 multicellular organismal process#GO:0032501;protein maturation#GO:0051604;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;response to wounding#GO:0009611;response to stress#GO:0006950;coagulation#GO:0050817;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;blood coagulation#GO:0007596;metabolic process#GO:0008152;response to stimulus#GO:0050896;regulation of body fluid levels#GO:0050878;primary metabolic process#GO:0044238;hemostasis#GO:0007599;zymogen activation#GO:0031638;protein metabolic process#GO:0019538;wound healing#GO:0042060;regulation of biological quality#GO:0065008;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000005717.1|UniProtKB=W5MEW0 W5MEW0 PTHR43084:SF1 PERSULFIDE DIOXYGENASE ETHE1 PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000015336.1|UniProtKB=W5NE10 W5NE10 PTHR21024:SF0 GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1 regulation of metabolic process#GO:0019222;negative regulation of cellular process#GO:0048523;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000014948.1|UniProtKB=W5NCP4 W5NCP4 PTHR22546:SF0 PREMATURE OVARIAN FAILURE, 1B PROTEIN POF1B cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;epithelial cell differentiation#GO:0030855;tissue development#GO:0009888;epithelium development#GO:0060429;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cell development#GO:0048468;actin cytoskeleton organization#GO:0030036;cell junction organization#GO:0034330;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;tight junction#GO:0070160;cell junction#GO:0030054;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical junction complex#GO:0043296;actin filament#GO:0005884;supramolecular polymer#GO:0099081;bicellular tight junction#GO:0005923;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cell-cell junction#GO:0005911;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 LEPOC|Ensembl=ENSLOCG00000006529.1|UniProtKB=W5MHN0 W5MHN0 PTHR22414:SF0 LEUCINE ZIPPER PROTEIN 2 LEUCINE ZIPPER PROTEIN 2 LEPOC|Ensembl=ENSLOCG00000010286.1|UniProtKB=W5MW36 W5MW36 PTHR48051:SF16 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 2 ISOFORM X1 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009959.1|UniProtKB=W5MUX0 W5MUX0 PTHR12146:SF0 40S RIBOSOMAL PROTEIN S10 RIBOSOMAL PROTEIN S10 binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000013081.1|UniProtKB=W5N654 W5N654 PTHR13513:SF9 E3 UBIQUITIN-PROTEIN LIGASE UBR7 E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007980.1|UniProtKB=W5MMT8 W5MMT8 PTHR10621:SF29 UV EXCISION REPAIR PROTEIN RAD23 LYSINE-SPECIFIC DEMETHYLASE RAD23A protein-containing complex binding#GO:0044877;protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014067.1|UniProtKB=W5N9N2 W5N9N2 PTHR48051:SF30 FAMILY NOT NAMED LEUCINE-RICH REPEAT SERINE_THREONINE-PROTEIN KINASE 1 ISOFORM X1 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009224.1|UniProtKB=W5MS95 W5MS95 PTHR19282:SF159 TETRASPANIN TETRASPANIN-15 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015439.1|UniProtKB=W5NEE2 W5NEE2 PTHR24229:SF7 NEUROPEPTIDES RECEPTOR MU-TYPE OPIOID RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;binding#GO:0005488;neuropeptide receptor activity#GO:0008188;protein binding#GO:0005515;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;sensory perception of pain#GO:0019233;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;system process#GO:0003008;signal transduction#GO:0007165;cellular process#GO:0009987;multicellular organismal process#GO:0032501;biological regulation#GO:0065007 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Opioid proopiomelanocortin pathway#P05917>Mu or Delta receptor#P06004;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Enkephalin release#P05913>GPCR (s)#P05975;Opioid proenkephalin pathway#P05915>Mu or Delta receptor#P05985;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000017380.1|UniProtKB=W5NLH6 W5NLH6 PTHR24061:SF528 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008289.1|UniProtKB=W5MNV8 W5MNV8 PTHR10165:SF17 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 5 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipid modification#GO:0030258;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154;dephosphorylation#GO:0016311 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000017648.1|UniProtKB=W5NM94 W5NM94 PTHR26451:SF966 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;system process#GO:0003008 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017130.1|UniProtKB=W5NKL3 W5NKL3 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001182.1|UniProtKB=W5LZ70 W5LZ70 PTHR23169:SF25 ENVOPLAKIN MICROTUBULE-ACTIN CROSS-LINKING FACTOR 1, ISOFORMS 1_2_3_4_5 regulation of cell junction assembly#GO:1901888;intermediate filament-based process#GO:0045103;regulation of microtubule-based process#GO:0032886;wound healing#GO:0042060;regulation of cell-matrix adhesion#GO:0001952;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;response to stimulus#GO:0050896;intermediate filament cytoskeleton organization#GO:0045104;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;response to wounding#GO:0009611;biological regulation#GO:0065007;regulation of cell-substrate adhesion#GO:0010810;cytoskeleton organization#GO:0007010;regulation of cell adhesion#GO:0030155 intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081 intermediate filament#PC00129;intermediate filament binding protein#PC00130 LEPOC|Ensembl=ENSLOCG00000011132.1|UniProtKB=W5MZ63 W5MZ63 PTHR14191:SF7 PDZ DOMAIN CONTAINING PROTEIN NA(+)_H(+) EXCHANGE REGULATORY COFACTOR NHE-RF1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515 intracellular protein localization#GO:0008104;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007291.1|UniProtKB=W5MKC0 W5MKC0 PTHR48226:SF1 OS06G0326200 PROTEIN WAS_WASL-INTERACTING PROTEIN FAMILY MEMBER 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cytoskeletal adaptor activity#GO:0008093 actin filament-based process#GO:0030029;cellular process#GO:0009987;actin filament-based movement#GO:0030048 cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000003353.1|UniProtKB=W5M6F0 W5M6F0 PTHR46109:SF2 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG A binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009160.1|UniProtKB=W5MS05 W5MS05 PTHR28453:SF2 PROTEIN SNORC PROTEIN SNORC LEPOC|Ensembl=ENSLOCG00000002392.1|UniProtKB=W5M362 W5M362 PTHR24092:SF49 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IIA-RELATED intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657 transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;vesicle-mediated transport#GO:0016192;lipid transport#GO:0006869;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;endocytosis#GO:0006897;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endomembrane system#GO:0012505;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;Golgi apparatus#GO:0005794 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000014313.1|UniProtKB=W5NAG5 W5NAG5 PTHR13948:SF4 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 10 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000015993.1|UniProtKB=W5NGD4 W5NGD4 PTHR32083:SF34 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 146 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000009864.1|UniProtKB=W5MUJ8 W5MUJ8 PTHR23251:SF2 LYSINE-RICH CEACAM1 CO-ISOLATED PROTEIN LYRIC PROTEIN METADHERIN transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000001743.1|UniProtKB=W5M0Z8 W5M0Z8 PTHR24020:SF18 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN muscle tissue development#GO:0060537;anatomical structure development#GO:0048856;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;skeletal muscle organ development#GO:0060538;cell development#GO:0048468;muscle structure development#GO:0061061;cell differentiation#GO:0030154;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;cellular developmental process#GO:0048869;developmental process#GO:0032502;striated muscle tissue development#GO:0014706;muscle organ development#GO:0007517;tissue development#GO:0009888;skeletal muscle tissue development#GO:0007519;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000008596.1|UniProtKB=W5MPZ8 W5MPZ8 PTHR10410:SF5 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED UBIQUITIN C-TERMINAL HYDROLASE PSMD14 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;proteasome complex#GO:0000502;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000014678.1|UniProtKB=W5NBQ7 W5NBQ7 PTHR16866:SF3 GASTRIN-RELEASING PEPTIDE NEUROMEDIN B G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;neuropeptide receptor binding#GO:0071855;protein binding#GO:0005515 positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;positive regulation of hormone secretion#GO:0046887;positive regulation of signaling#GO:0023056;regulation of hormone secretion#GO:0046883;regulation of secretion#GO:0051046;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530 LEPOC|Ensembl=ENSLOCG00000015114.1|UniProtKB=W5ND99 W5ND99 PTHR11730:SF124 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE C-LIKE 2-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;homeostatic process#GO:0042592 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000016302.1|UniProtKB=W5NHL0 W5NHL0 PTHR11534:SF3 MYOGENIC FACTOR MYOGENIC FACTOR 5 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;skeletal muscle organ development#GO:0060538;animal gross anatomical part developmental process#GO:0160108;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;muscle organ development#GO:0007517;positive regulation of cell differentiation#GO:0045597;striated muscle tissue development#GO:0014706;animal organ development#GO:0048513;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;muscle tissue development#GO:0060537;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;skeletal muscle tissue development#GO:0007519;positive regulation of cellular process#GO:0048522;tissue development#GO:0009888;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001473.1|UniProtKB=W5M067 W5M067 PTHR24023:SF372 COLLAGEN ALPHA COLLAGEN ALPHA-1(XVI) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000018202.1|UniProtKB=W5NNU4 W5NNU4 PTHR24373:SF394 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE RICH REPEAT CONTAINING 3C signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000003774.1|UniProtKB=W5M7Z0 W5M7Z0 PTHR12622:SF48 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000011370.1|UniProtKB=W5N025 W5N025 PTHR42757:SF34 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED MAM DOMAIN CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR 2 heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000017683.1|UniProtKB=W5NMC9 W5NMC9 PTHR11021:SF1 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 rRNA processing#GO:0006364;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397 intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;P-body#GO:0000932;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;small nuclear ribonucleoprotein complex#GO:0030532;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U6 snRNP#GO:0005688 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000010000.1|UniProtKB=W5MV16 W5MV16 PTHR12021:SF3 THYMOSIN BETA THYMOSIN BETA-RELATED molecular sequestering activity#GO:0140313;binding#GO:0005488;protein sequestering activity#GO:0140311;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin monomer binding#GO:0003785;protein binding#GO:0005515 regulation of cell migration#GO:0030334;regulation of biological process#GO:0050789;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell motility#GO:2000145 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000012886.1|UniProtKB=W5N5G2 W5N5G2 PTHR10758:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502 protein modifying enzyme#PC00260;protease#PC00190 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000003127.1|UniProtKB=W5M5Q8 W5M5Q8 PTHR21439:SF0 OXIDORED-NITRO DOMAIN-CONTAINING PROTEIN PROTEIN OSCP1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000018033.1|UniProtKB=W5NNC5 W5NNC5 PTHR26451:SF854 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to stimulus#GO:0050896;nervous system process#GO:0050877;sensory perception#GO:0007600;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000016606.1|UniProtKB=W5NIQ1 W5NIQ1 PTHR21356:SF2 ARMADILLO REPEAT CONTAINING 2 ARMADILLO REPEAT-CONTAINING PROTEIN 2 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;spermatid differentiation#GO:0048515;cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;flagellated sperm motility#GO:0030317;spermatogenesis#GO:0007283;developmental process#GO:0032502;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;cell motility#GO:0048870;microtubule-based movement#GO:0007018;reproductive process#GO:0022414;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609 LEPOC|Ensembl=ENSLOCG00000008616.1|UniProtKB=W5MQ15 W5MQ15 PTHR22752:SF10 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 161 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000001862.1|UniProtKB=W5M1A3 W5M1A3 PTHR22957:SF598 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 26 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000012376.1|UniProtKB=W5N3P7 W5N3P7 PTHR45761:SF2 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-2 phospholipid binding#GO:0005543;phosphatidylinositol binding#GO:0035091;phosphatidylcholine binding#GO:0031210;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169;lipid binding#GO:0008289 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001457.1|UniProtKB=W5LZV3 W5LZV3 PTHR45632:SF33 LD33804P KELCH-LIKE PROTEIN 26 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005012.1|UniProtKB=W5MCC6 W5MCC6 PTHR45619:SF67 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 CATALYTIC SUBUNIT catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000007234.1|UniProtKB=W5MK46 W5MK46 PTHR24393:SF151 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 956 nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000002116.1|UniProtKB=W5M254 W5M254 PTHR11097:SF8 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP42 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA catabolic process#GO:0006401;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 exoribonuclease#PC00099;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015373.1|UniProtKB=W5NE58 W5NE58 PTHR24034:SF102 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 1 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000017924.1|UniProtKB=W5NN18 W5NN18 PTHR24072:SF306 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOH nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900 signaling#GO:0023052;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;establishment or maintenance of cell polarity#GO:0007163;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;actin filament organization#GO:0007015;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000010666.1|UniProtKB=W5MXG1 W5MXG1 PTHR11746:SF150 O-METHYLTRANSFERASE ACETYLSEROTONIN O-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 metabolic process#GO:0008152;regulation of biological quality#GO:0065008;methylation#GO:0032259;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;biological regulation#GO:0065007;hormone biosynthetic process#GO:0042446;biosynthetic process#GO:0009058;hormone metabolic process#GO:0042445 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000007960.1|UniProtKB=W5MMS3 W5MMS3 PTHR24241:SF135 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010632.1|UniProtKB=W5MXB3 W5MXB3 PTHR23327:SF5 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 2 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cell death#GO:0008219;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;system development#GO:0048731;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;macromolecule metabolic process#GO:0043170;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;apoptotic process#GO:0006915;neuron apoptotic process#GO:0051402;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;protein catabolic process#GO:0030163;generation of neurons#GO:0048699;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;neuron differentiation#GO:0030182 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000004155.1|UniProtKB=W5M9G3 W5M9G3 PTHR11733:SF141 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED MEMBRANE METALLO-ENDOPEPTIDASE-LIKE 1 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014120.1|UniProtKB=W5N9T7 W5N9T7 PTHR36129:SF3 ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA-RELATED SOLUTE CARRIER FAMILY 51 SUBUNIT BETA ISOFORM X1 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000014382.1|UniProtKB=W5NAP7 W5NAP7 PTHR20855:SF35 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to peptide#GO:1901652;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to endogenous stimulus#GO:0009719;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003264.1|UniProtKB=W5M651 W5M651 PTHR18947:SF38 HOOK PROTEINS PROTEIN HOOK HOMOLOG 3 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 supramolecular fiber organization#GO:0097435;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;cytoplasmic microtubule organization#GO:0031122;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;cytoskeleton organization#GO:0007010;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000936.1|UniProtKB=W5LY58 W5LY58 PTHR11091:SF0 OXIDOREDUCTASE-RELATED MALATE DEHYDROGENASE oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Allantoin degradation#P02725>Ureidoglycolate dehydrogenase#P02820;TCA cycle#P00051>Malate Dehydrogenase#P01270;Pyruvate metabolism#P02772>Malate Dehydrogenase#P03138 LEPOC|Ensembl=ENSLOCG00000012197.1|UniProtKB=W5N302 W5N302 PTHR24381:SF453 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 770 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000010439.1|UniProtKB=W5MWP3 W5MWP3 PTHR44535:SF1 PROTEIN CBG16200 SERINE_THREONINE-PROTEIN KINASE NEK9 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular process#GO:0009987 LEPOC|Ensembl=ENSLOCG00000003190.1|UniProtKB=W5M5W4 W5M5W4 PTHR24322:SF483 PKSB SHORT-CHAIN DEHYDROGENASE_REDUCTASE 3 all-trans-retinol dehydrogenase (NAD+) activity#GO:0004745;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;isoprenoid metabolic process#GO:0006720;regulation of signaling#GO:0023051;terpenoid metabolic process#GO:0006721;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;lipid metabolic process#GO:0006629;regulation of response to stimulus#GO:0048583;metabolic process#GO:0008152 intracellular organelle#GO:0043229;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000011032.1|UniProtKB=W5MYT8 W5MYT8 PTHR13944:SF22 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 28 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 CCKR signaling map#P06959>p190RhoGEF#P07157 LEPOC|Ensembl=ENSLOCG00000007742.1|UniProtKB=W5MLZ0 W5MLZ0 PTHR48051:SF15 FAMILY NOT NAMED SI:ZFOS-323E3.4 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004010.1|UniProtKB=W5M8T0 W5M8T0 PTHR14657:SF2 IGF-LIKE FAMILY RECEPTOR 1 IGF-LIKE FAMILY RECEPTOR 1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002210.1|UniProtKB=W5M2I8 W5M2I8 PTHR11142:SF33 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE SYNTHASE-LIKE 1 catalytic activity, acting on a tRNA#GO:0140101;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;intramolecular transferase activity#GO:0016866;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;pseudouridine synthesis#GO:0001522;mRNA modification#GO:0016556;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000012057.1|UniProtKB=W5N2H8 W5N2H8 PTHR46318:SF2 UPSTREAM BINDING TRANSCRIPTION FACTOR NUCLEOLAR TRANSCRIPTION FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase I#GO:0045943;positive regulation of RNA biosynthetic process#GO:1902680;transcription by RNA polymerase I#GO:0006360;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase I#GO:0006356;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;nucleic acid biosynthetic process#GO:0141187;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000013250.1|UniProtKB=W5N6R3 W5N6R3 PTHR24234:SF9 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 132-RELATED G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003250.1|UniProtKB=W5M636 W5M636 PTHR11562:SF37 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A8 metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915 hormone transport#GO:0009914;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;response to chemical#GO:0042221;cellular process#GO:0009987;establishment of protein localization#GO:0045184;monoatomic ion transport#GO:0006811;hormone secretion#GO:0046879;protein transport#GO:0015031;regulation of biological quality#GO:0065008;secretion by cell#GO:0032940;response to carbohydrate#GO:0009743;transmembrane transport#GO:0055085;protein secretion#GO:0009306;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;response to oxygen-containing compound#GO:1901700;response to monosaccharide#GO:0034284;signaling#GO:0023052;export from cell#GO:0140352;response to stimulus#GO:0050896;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;response to hexose#GO:0009746;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;response to metal ion#GO:0010038;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;response to glucose#GO:0009749;insulin secretion#GO:0030073;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;macromolecule localization#GO:0033036;peptide hormone secretion#GO:0030072;secretion#GO:0046903;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;peptide secretion#GO:0002790;signal release#GO:0023061;metal ion transport#GO:0030001;protein localization to extracellular region#GO:0071692 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013933.1|UniProtKB=W5N971 W5N971 PTHR10782:SF11 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS1 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678 protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;metabolic process#GO:0008152;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;protein sumoylation#GO:0016925 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785 ubiquitin-protein ligase#PC00234 JAK/STAT signaling pathway#P00038>PIAS#P01031;Interferon-gamma signaling pathway#P00035>PIAS#P00958 LEPOC|Ensembl=ENSLOCG00000016568.1|UniProtKB=W5NIK6 W5NIK6 PTHR16262:SF2 PEROXISOME ASSEMBLY PROTEIN 26 PEROXISOME ASSEMBLY PROTEIN 26 enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515 intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;peroxisomal transport#GO:0043574;protein transport#GO:0015031;peroxisome organization#GO:0007031;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000002313.1|UniProtKB=W5M2W2 W5M2W2 PTHR42884:SF37 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000000418.1|UniProtKB=W5LWF1 W5LWF1 PTHR12998:SF0 TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA methylation#GO:0001510;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 LEPOC|Ensembl=ENSLOCG00000015276.1|UniProtKB=W5NDT9 W5NDT9 PTHR11276:SF24 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA-DIRECTED DNA_RNA POLYMERASE MU catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 LEPOC|Ensembl=ENSLOCG00000004956.1|UniProtKB=W5MC63 W5MC63 PTHR44027:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of transport#GO:0051049;regulation of localization#GO:0032879;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular process#GO:0050794;protein folding#GO:0006457;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell junction#GO:0030054;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;presynapse#GO:0098793;membrane#GO:0016020 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000011039.1|UniProtKB=W5MYT5 W5MYT5 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005124.1|UniProtKB=W5MCR2 W5MCR2 PTHR47992:SF253 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1D kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;mitogen-activated protein kinase binding#GO:0051019 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;regulation of cell communication#GO:0010646;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule biosynthetic process#GO:0010558;chromatin organization#GO:0006325;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>WIP-1#G04708;p53 pathway#P00059>WIP-1#G04693;p53 pathway feedback loops 2#P04398>WIP-1#P04650 LEPOC|Ensembl=ENSLOCG00000006739.1|UniProtKB=W5MID1 W5MID1 PTHR23503:SF129 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 transport#GO:0006810;carbohydrate transport#GO:0008643;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180;import across plasma membrane#GO:0098739 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000007472.1|UniProtKB=W5ML09 W5ML09 PTHR22739:SF21 STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED ACTIN-BINDING RHO-ACTIVATING PROTEIN positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of signal transduction#GO:0009967;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of response to stimulus#GO:0048584;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of transcription by RNA polymerase II#GO:0006357;regulation of Rho protein signal transduction#GO:0035023;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of transcription by RNA polymerase II#GO:0045944 sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292 LEPOC|Ensembl=ENSLOCG00000001531.1|UniProtKB=W5M071 W5M071 PTHR14043:SF4 CCAAT DISPLACEMENT PROTEIN-RELATED HOMEOBOX PROTEIN CUT-LIKE 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000016008.1|UniProtKB=W5NGF8 W5NGF8 PTHR13479:SF66 30S RIBOSOMAL PROTEIN S18 LARGE RIBOSOMAL SUBUNIT PROTEIN ML66 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000018189.1|UniProtKB=W5NNT1 W5NNT1 PTHR22750:SF8 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 12 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017022.1|UniProtKB=W5NK81 W5NK81 PTHR13255:SF1 ATAXIN-10 ATAXIN-10 neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;organelle organization#GO:0006996;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;organelle assembly#GO:0070925;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cilium organization#GO:0044782;neuron development#GO:0048666;anatomical structure development#GO:0048856;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154 intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cytosol#GO:0005829;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000003266.1|UniProtKB=W5M658 W5M658 PTHR21723:SF3 RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 RIC3 PROTEIN RIC-3 anterograde trans-synaptic signaling#GO:0098916;synaptic transmission, cholinergic#GO:0007271;signaling#GO:0023052;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;macromolecule localization#GO:0033036;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular process#GO:0009987;localization#GO:0051179;cell communication#GO:0007154;intracellular protein localization#GO:0008104;trans-synaptic signaling#GO:0099537 neuron projection#GO:0043005;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000017492.1|UniProtKB=W5NLT8 W5NLT8 PTHR24248:SF176 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 101-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000012495.1|UniProtKB=W5N423 W5N423 PTHR10607:SF2 OSTEOPONTIN OSTEOPONTIN-RELATED protein binding#GO:0005515;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839 cellular process#GO:0009987;cell adhesion#GO:0007155 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cytokine#PC00083;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000010338.1|UniProtKB=W5MWA3 W5MWA3 PTHR14969:SF18 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE POLYISOPRENOID DIPHOSPHATE_PHOSPHATE PHOSPHOHYDROLASE PLPP6 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;dephosphorylation#GO:0016311;lipid modification#GO:0030258 cellular anatomical structure#GO:0110165;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000010617.1|UniProtKB=W5MX93 W5MX93 PTHR45809:SF4 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 3 cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;growth factor receptor binding#GO:0070851;protein binding#GO:0005515 animal gross anatomical part developmental process#GO:0160108;angiogenesis#GO:0001525;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;blood vessel morphogenesis#GO:0048514;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;circulatory system development#GO:0072359;protein folding#GO:0006457;metabolic process#GO:0008152;multicellular organism development#GO:0007275;anatomical structure formation involved in morphogenesis#GO:0048646;vasculature development#GO:0001944;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;protein maturation#GO:0051604;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;primary metabolic process#GO:0044238;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;tube development#GO:0035295;biosynthetic process#GO:0009058;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000002495.1|UniProtKB=W5M3H9 W5M3H9 PTHR16243:SF2 BTG3-ASSOCIATED NUCLEAR PROTEIN BANP PROTEIN BANP LEPOC|Ensembl=ENSLOCG00000001737.1|UniProtKB=W5M0U9 W5M0U9 PTHR23507:SF36 ZGC:174356 SOLUTE CARRIER FAMILY 46 MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000006949.1|UniProtKB=W5MJ58 W5MJ58 PTHR22802:SF471 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR-LIKE 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;binding#GO:0005488 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004638.1|UniProtKB=W5MB22 W5MB22 PTHR14516:SF3 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 dehydrogenase#PC00092;oxidoreductase#PC00176 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 LEPOC|Ensembl=ENSLOCG00000011249.1|UniProtKB=W5MZL3 W5MZL3 PTHR12800:SF2 CDC37-RELATED HSP90 CO-CHAPERONE CDC37-LIKE 1 heat shock protein binding#GO:0031072;binding#GO:0005488;protein binding#GO:0005515 regulation of protein stability#GO:0031647;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein folding chaperone complex#GO:0101031 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009076.1|UniProtKB=W5MRR3 W5MRR3 PTHR22765:SF42 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING FINGER PROTEIN 150 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009248.1|UniProtKB=W5MSB8 W5MSB8 PTHR24023:SF1002 COLLAGEN ALPHA C1Q DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000018107.1|UniProtKB=W5NNJ9 W5NNJ9 PTHR10656:SF9 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN-LIKE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleotidyltransferase#PC00174;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000014645.1|UniProtKB=W5NBM5 W5NBM5 PTHR10663:SF314 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 2 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of endocytosis#GO:0030100;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008 membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000002728.1|UniProtKB=W5M4A3 W5M4A3 PTHR13264:SF5 GCIP-INTERACTING PROTEIN P29 PRE-MRNA-SPLICING FACTOR SYF2 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000002431.1|UniProtKB=W5M398 W5M398 PTHR24230:SF1 G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 54-2 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 positive regulation of hormone secretion#GO:0046887;positive regulation of secretion#GO:0051047;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;regulation of biological quality#GO:0065008;regulation of secretion by cell#GO:1903530;regulation of hormone secretion#GO:0046883;cell communication#GO:0007154;regulation of secretion#GO:0051046;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001726.1|UniProtKB=W5M0T4 W5M0T4 PTHR46212:SF10 PEFLIN PEFLIN COPII-coated vesicle budding#GO:0090114;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;membrane organization#GO:0061024 LEPOC|Ensembl=ENSLOCG00000011149.1|UniProtKB=W5MZ86 W5MZ86 PTHR23065:SF9 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000012526.1|UniProtKB=W5N467 W5N467 PTHR47977:SF102 RAS-RELATED PROTEIN RAB RAB44, MEMBER RAS ONCOGENE FAMILY GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;transport#GO:0006810 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000010579.1|UniProtKB=W5MX52 W5MX52 PTHR15975:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;CCR4-NOT complex#GO:0030014 LEPOC|Ensembl=ENSLOCG00000001045.1|UniProtKB=W5LYG7 W5LYG7 PTHR11375:SF25 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016543.1|UniProtKB=W5NIH1 W5NIH1 PTHR21711:SF0 MITOCHONDRIAL INNER MEMBRANE PROTEASE MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;biosynthetic process#GO:0009058;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;proteolysis#GO:0006508;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000018343.1|UniProtKB=W5NP85 W5NP85 PTHR13832:SF627 PROTEIN PHOSPHATASE 2C [PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 1, MITOCHONDRIAL protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000003684.1|UniProtKB=W5M7L1 W5M7L1 PTHR22409:SF2 CHROMOSOME 19 OPEN READING FRAME 44 CHROMOSOME 19 OPEN READING FRAME 44 LEPOC|Ensembl=ENSLOCG00000005210.1|UniProtKB=W5MD18 W5MD18 PTHR12537:SF1 RNA BINDING PROTEIN PUMILIO-RELATED PUMILIO HOMOLOG 1 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000003092.1|UniProtKB=W5M5H8 W5M5H8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003542.1|UniProtKB=W5M751 W5M751 PTHR11610:SF3 LIPASE LIPOPROTEIN LIPASE protein binding#GO:0005515;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;multicellular organismal process#GO:0032501;catabolic process#GO:0009056;biological regulation#GO:0065007;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;lipid catabolic process#GO:0016042;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 2-arachidonoylglycerol biosynthesis#P05726>DGL#P05736 LEPOC|Ensembl=ENSLOCG00000014944.1|UniProtKB=W5NCP3 W5NCP3 PTHR45618:SF20 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED BRAIN MITOCHONDRIAL CARRIER PROTEIN 1 monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;proton transmembrane transporter activity#GO:0015078 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;regulation of cellular response to stress#GO:0080135;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006134.1|UniProtKB=W5MGA6 W5MGA6 PTHR10623:SF7 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 2 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;cell cycle#GO:0007049;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;protein localization to microtubule cytoskeleton#GO:0072698;cellular component assembly#GO:0022607;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;chromosome segregation#GO:0007059 microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;microtubule cytoskeleton#GO:0015630;supramolecular fiber#GO:0099512;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule end#GO:1990752;cytoplasmic microtubule#GO:0005881 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000014750.1|UniProtKB=W5NC20 W5NC20 PTHR46055:SF4 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT PAS DOMAIN CONTAINING REPRESSOR 1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;circadian rhythm#GO:0007623;regulation of RNA metabolic process#GO:0051252;rhythmic process#GO:0048511 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004766.1|UniProtKB=W5MBG2 W5MBG2 PTHR43128:SF2 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE B CHAIN oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;energy derivation by oxidation of organic compounds#GO:0015980 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000008255.1|UniProtKB=W5MNQ7 W5MNQ7 PTHR12308:SF40 ANOCTAMIN ANOCTAMIN-10 molecular carrier activity#GO:0140104;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;ligand-gated monoatomic ion channel activity#GO:0015276;intramembrane lipid carrier activity#GO:0140303;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation channel activity#GO:0005261 organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;monoatomic anion transport#GO:0006820;cellular component organization#GO:0016043;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;lipid transport#GO:0006869;monoatomic anion transmembrane transport#GO:0098656;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;macromolecule localization#GO:0033036;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;chloride transport#GO:0006821;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000017453.1|UniProtKB=W5NLP9 W5NLP9 PTHR26451:SF847 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;sensory perception#GO:0007600;nervous system process#GO:0050877;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;system process#GO:0003008 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011579.1|UniProtKB=W5N0R5 W5N0R5 PTHR24044:SF507 NOTCH LIGAND FAMILY MEMBER NOTCH HOMOLOG 2 N-TERMINAL-LIKE PROTEIN B signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000004736.1|UniProtKB=W5MBB5 W5MBB5 PTHR11767:SF106 INWARD RECTIFIER POTASSIUM CHANNEL POTASSIUM INWARDLY RECTIFYING CHANNEL SUBFAMILY J MEMBER 21 passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;transport#GO:0006810;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000007770.1|UniProtKB=W5MM27 W5MM27 PTHR11442:SF97 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ALPHA-D-LIKE heme binding#GO:0020037;molecular carrier activity#GO:0140104;binding#GO:0005488;tetrapyrrole binding#GO:0046906 hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;cellular process#GO:0009987;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;cell development#GO:0048468;homeostatic process#GO:0042592;myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;localization#GO:0051179;homeostasis of number of cells#GO:0048872;immune system process#GO:0002376 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219;globin#PC00107 LEPOC|Ensembl=ENSLOCG00000000429.1|UniProtKB=W5LWH5 W5LWH5 PTHR12011:SF290 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G6 extracellular matrix binding#GO:0050840;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;laminin binding#GO:0043236;binding#GO:0005488;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930 regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;cellular response to stimulus#GO:0051716;heart morphogenesis#GO:0003007;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;biological regulation#GO:0065007;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental process#GO:0032502;cell development#GO:0048468;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;peripheral nervous system development#GO:0007422;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;nervous system development#GO:0007399;heart development#GO:0007507;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure formation involved in morphogenesis#GO:0048646;myelination#GO:0042552;gliogenesis#GO:0042063;animal organ development#GO:0048513;multicellular organism development#GO:0007275;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000004386.1|UniProtKB=W5MA55 W5MA55 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER PANCREATIC ELASTASE serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013773.1|UniProtKB=W5N8M5 W5N8M5 PTHR45635:SF14 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;purine nucleotide transmembrane transporter activity#GO:0015216;active transmembrane transporter activity#GO:0022804 regulation of mitochondrial membrane permeability#GO:0046902;biological regulation#GO:0065007;regulation of membrane permeability#GO:0090559;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;regulation of biological quality#GO:0065008;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000018276.1|UniProtKB=W5NP18 W5NP18 PTHR17045:SF5 MELANOCYTE SPECIFIC GENE RELATED CITED CBP_P300-INTERACTING TRANSACTIVATOR 4 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of RNA metabolic process#GO:0051254;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 LEPOC|Ensembl=ENSLOCG00000001361.1|UniProtKB=W5LZI3 W5LZI3 PTHR22811:SF45 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 6 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;vesicle#GO:0031982 vesicle coat protein#PC00235;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006793.1|UniProtKB=W5MIJ6 W5MIJ6 PTHR23424:SF29 SERUM AMYLOID A SERUM AMYLOID A PROTEIN transfer/carrier protein#PC00219;apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000006142.1|UniProtKB=W5MGB5 W5MGB5 NUBP1 PTHR23264:SF35 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011680.1|UniProtKB=W5N146 W5N146 PTHR22950:SF188 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 1 solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;glycine transmembrane transporter activity#GO:0015187;proton transmembrane transporter activity#GO:0015078;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943 carboxylic acid transmembrane transport#GO:1905039;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;organic acid transport#GO:0015849;alanine transport#GO:0032328 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;vacuolar membrane#GO:0005774;membrane#GO:0016020;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 LEPOC|Ensembl=ENSLOCG00000016673.1|UniProtKB=W5NIZ1 W5NIZ1 PTHR12181:SF10 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN1 hydrolase activity#GO:0016787;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;carboxylic acid catabolic process#GO:0046395;glycerolipid biosynthetic process#GO:0045017;triglyceride biosynthetic process#GO:0019432;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699;monocarboxylic acid catabolic process#GO:0072329;positive regulation of DNA-templated transcription#GO:0045893;lipid biosynthetic process#GO:0008610;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;response to peptide hormone#GO:0043434;fatty acid metabolic process#GO:0006631;acylglycerol metabolic process#GO:0006639;cellular response to insulin stimulus#GO:0032869;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;neutral lipid metabolic process#GO:0006638;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to peptide hormone stimulus#GO:0071375;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;response to hormone#GO:0009725;cellular response to oxygen-containing compound#GO:1901701;lipid catabolic process#GO:0016042;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;response to endogenous stimulus#GO:0009719;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;regulation of biological process#GO:0050789;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;glycerolipid metabolic process#GO:0046486;cellular response to hormone stimulus#GO:0032870;small molecule catabolic process#GO:0044282;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;fatty acid catabolic process#GO:0009062 membrane#GO:0016020;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000000316.1|UniProtKB=W5LW43 W5LW43 PTHR14063:SF5 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG C molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;secretion by cell#GO:0032940;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;regulation of synapse organization#GO:0050807;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle transport#GO:0048489;synaptic signaling#GO:0099536;regulation of developmental process#GO:0050793;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of growth#GO:0040008;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;signal release#GO:0023061;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;regulation of synapse assembly#GO:0051963;vesicle localization#GO:0051648;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synapse#GO:0045202;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;anchoring junction#GO:0070161 cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000016381.1|UniProtKB=W5NHX5 W5NHX5 PTHR10357:SF240 ALPHA-GLUCOSIDASE FAMILY MEMBER AMINO ACID TRANSPORTER HEAVY CHAIN SLC3A1 primary metabolic process#GO:0044238;cellular process#GO:0009987;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;carbohydrate catabolic process#GO:0016052;establishment of localization#GO:0051234;oligosaccharide metabolic process#GO:0009311 brush border membrane#GO:0031526;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;brush border#GO:0005903;cell periphery#GO:0071944;cell projection membrane#GO:0031253;cluster of actin-based cell projections#GO:0098862;apical part of cell#GO:0045177 metabolite interconversion enzyme#PC00262;amylase#PC00048 LEPOC|Ensembl=ENSLOCG00000005519.1|UniProtKB=W5ME65 W5ME65 PTHR22753:SF14 TRANSMEMBRANE PROTEIN 68 DGAT1_2-INDEPENDENT ENZYME SYNTHESIZING STORAGE LIPIDS membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013627.1|UniProtKB=W5N842 W5N842 PTHR24136:SF18 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 5 positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;positive regulation of protein metabolic process#GO:0051247;protein modification by small protein conjugation or removal#GO:0070647;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246 LEPOC|Ensembl=ENSLOCG00000016275.1|UniProtKB=W5NHG7 W5NHG7 PTHR10972:SF216 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 8 steroid binding#GO:0005496;lipid binding#GO:0008289;cholesterol binding#GO:0015485;alcohol binding#GO:0043178;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000016744.1|UniProtKB=W5NJ92 W5NJ92 PTHR22589:SF69 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 1, MUSCLE ISOFORM acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;carnitine metabolic process#GO:0009437;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;lipid metabolic process#GO:0006629;transport#GO:0006810;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;establishment of localization#GO:0051234;cellular process#GO:0009987;macromolecule localization#GO:0033036;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000006177.1|UniProtKB=W5MGF5 W5MGF5 PTHR12449:SF17 DEATH DOMAIN-CONTAINING PROTEIN NUCLEOLAR PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000002839.1|UniProtKB=W5M4Q3 W5M4Q3 PTHR13673:SF0 ESOPHAGEAL CANCER ASSOCIATED PROTEIN VPS35 ENDOSOMAL PROTEIN-SORTING FACTOR-LIKE establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 LEPOC|Ensembl=ENSLOCG00000012028.1|UniProtKB=W5N2D3 W5N2D3 PTHR24055:SF162 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 10 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of cellular process#GO:0050794;JNK cascade#GO:0007254;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Angiogenesis#P00005>JNK1#P00221;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Ras Pathway#P04393>JNK#P04572;B cell activation#P00010>Jnk#P00402;PDGF signaling pathway#P00047>ERK#P01143;CCKR signaling map#P06959>MAPK8-10#P07090;Apoptosis signaling pathway#P00006>JNK#P00274;Integrin signalling pathway#P00034>ERK#P00907;Parkinson disease#P00049>SAPK#P01219;Toll receptor signaling pathway#P00054>JNK#P01375;Oxidative stress response#P00046>JNK1/2#P01129;FGF signaling pathway#P00021>JNK1-3#P00628;TGF-beta signaling pathway#P00052>JNK#P01284;T cell activation#P00053>Jnk#P01336;FAS signaling pathway#P00020>JNK#P00615;EGF receptor signaling pathway#P00018>JNK1-3#P00545;Integrin signalling pathway#P00034>Jnk#P00951 LEPOC|Ensembl=ENSLOCG00000000437.1|UniProtKB=W5LWH6 W5LWH6 PTHR46890:SF1 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED SECRETED RXLR EFFECTOR PROTEIN 78-LIKE reverse transcriptase#PC00200;viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000004825.1|UniProtKB=W5MBN7 W5MBN7 PTHR16500:SF3 BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000008279.1|UniProtKB=W5MNU7 W5MNU7 PTHR24071:SF17 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule biosynthetic process#GO:0009059;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;biosynthetic process#GO:0009058;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;organelle localization#GO:0051640;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;protein export from nucleus#GO:0006611;gene expression#GO:0010467;ribosome biogenesis#GO:0042254;protein transport#GO:0015031;protein import into nucleus#GO:0006606;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;ribosomal large subunit export from nucleus#GO:0000055;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656 nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000003975.1|UniProtKB=W5M8S9 W5M8S9 PTHR13931:SF16 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 A transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000012338.1|UniProtKB=W5N3I1 W5N3I1 PTHR10106:SF14 CYTOCHROME B561-RELATED TRANSMEMBRANE ASCORBATE-DEPENDENT REDUCTASE CYB561 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;carbohydrate homeostasis#GO:0033500;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000008755.1|UniProtKB=W5MQK5 W5MQK5 PTHR22808:SF31 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173 cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;tRNA wobble base modification#GO:0002097;protein-containing complex assembly#GO:0065003;tRNA modification#GO:0006400;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;methylation#GO:0032259;RNA metabolic process#GO:0016070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;tRNA methylation#GO:0030488;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;protein-RNA complex organization#GO:0071826;tRNA processing#GO:0008033;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mitochondrial large ribosomal subunit assembly#GO:1902775;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;mitochondrial ribosome assembly#GO:0061668 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 LEPOC|Ensembl=ENSLOCG00000001273.1|UniProtKB=W5LZ88 W5LZ88 PTHR23176:SF108 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 15 nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 LEPOC|Ensembl=ENSLOCG00000013279.1|UniProtKB=W5N6W0 W5N6W0 PTHR13115:SF8 RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 LEPOC|Ensembl=ENSLOCG00000013774.1|UniProtKB=W5N8M6 W5N8M6 PTHR14186:SF20 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED IGFBP DOMAIN-CONTAINING PROTEIN ISOFORM X1 molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000003246.1|UniProtKB=W5M646 W5M646 PTHR43150:SF7 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-1 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;protein binding#GO:0005515;channel regulator activity#GO:0016247;binding#GO:0005488;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;potassium channel regulator activity#GO:0015459;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;ion channel regulator activity#GO:0099106 biological regulation#GO:0065007;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of transmembrane transport#GO:0034762;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062 transmembrane transporter complex#GO:1902495;axon#GO:0030424;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;main axon#GO:0044304;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000003944.1|UniProtKB=W5M8K9 W5M8K9 PTHR23161:SF2 PROTEIN CIP2A PROTEIN CIP2A enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212 cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;cellular component organization#GO:0016043;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cytosol#GO:0005829;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000012167.1|UniProtKB=W5N2V7 W5N2V7 PTHR11630:SF71 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM3 isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;DNA strand elongation involved in DNA replication#GO:0006271;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA replication initiation#GO:0006270;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;cell cycle DNA replication#GO:0044786;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;double-strand break repair via break-induced replication#GO:0000727;response to stress#GO:0006950 MCM complex#GO:0042555;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000007925.1|UniProtKB=W5MML2 W5MML2 PTHR31592:SF1 TRANSMEMBRANE PROTEIN 192 TRANSMEMBRANE PROTEIN 192 vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosomal membrane#GO:0005765;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;vesicle#GO:0031982 LEPOC|Ensembl=ENSLOCG00000006685.1|UniProtKB=W5MI64 W5MI64 PTHR10019:SF18 SNF5 SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY B MEMBER 1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000006927.1|UniProtKB=W5MJ27 W5MJ27 PTHR13587:SF7 INTEGRATOR COMPLEX SUBUNIT 3 INTEGRATOR COMPLEX SUBUNIT 3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017606.1|UniProtKB=W5NM52 W5NM52 PTHR24229:SF35 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 4 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neuropeptide receptor activity#GO:0008188;binding#GO:0005488;peptide binding#GO:0042277;neuropeptide binding#GO:0042923;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cellular response to steroid hormone stimulus#GO:0071383;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;cellular response to lipid#GO:0071396;response to lipid#GO:0033993;response to chemical#GO:0042221;response to steroid hormone#GO:0048545;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 LEPOC|Ensembl=ENSLOCG00000011133.1|UniProtKB=W5MZ60 W5MZ60 PTHR12080:SF59 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE HEPATIC AND GLIAL CELL ADHESION MOLECULE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 macromolecule localization#GO:0033036;signal transduction#GO:0007165;regulation of biological process#GO:0050789;immune response#GO:0006955;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;immune system process#GO:0002376;protein localization to cell junction#GO:1902414;cell communication#GO:0007154;localization#GO:0051179;intracellular protein localization#GO:0008104 anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000010193.1|UniProtKB=W5MVR8 W5MVR8 PTHR10164:SF5 ISLET CELL AUTOANTIGEN 1 ISLET CELL AUTOANTIGEN 1-LIKE PROTEIN molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;membrane organization#GO:0061024;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000002233.1|UniProtKB=W5M2K3 W5M2K3 PTHR10972:SF47 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 10 sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094;lipid binding#GO:0008289;cholesterol binding#GO:0015485;steroid binding#GO:0005496;alcohol binding#GO:0043178 membrane#GO:0016020;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000008044.1|UniProtKB=W5MN09 W5MN09 PTHR23343:SF4 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 structural molecule activity#GO:0005198;protein binding#GO:0005515;enzyme binding#GO:0019899;extracellular matrix structural constituent#GO:0005201;binding#GO:0005488 cell-cell recognition#GO:0009988;binding of sperm to zona pellucida#GO:0007339;sexual reproduction#GO:0019953;cell activation#GO:0001775;cell recognition#GO:0008037;sperm-egg recognition#GO:0035036;biological regulation#GO:0065007;fertilization#GO:0009566;reproductive process#GO:0022414;regulation of reproductive process#GO:2000241;multicellular organismal process#GO:0032501;regulation of biological process#GO:0050789;cellular process#GO:0009987;negative regulation of biological process#GO:0048519;single fertilization#GO:0007338 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002902.1|UniProtKB=W5M4V0 W5M4V0 PTHR24403:SF43 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 64 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000005777.1|UniProtKB=W5MF14 W5MF14 PTHR12253:SF44 RH14732P PHOSPHOLIPASE A2 LEPOC|Ensembl=ENSLOCG00000013226.1|UniProtKB=W5N6N6 W5N6N6 PTHR24034:SF107 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-5 extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;supramolecular fiber organization#GO:0097435;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;extracellular matrix assembly#GO:0085029;cellular component assembly#GO:0022607 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000014744.1|UniProtKB=W5NBZ2 W5NBZ2 PTHR37948:SF1 ZGC:113208 BLR2476 PROTEIN LEPOC|Ensembl=ENSLOCG00000004723.1|UniProtKB=W5MB96 W5MB96 PTHR12522:SF3 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN 503 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000007514.1|UniProtKB=W5ML60 W5ML60 PTHR24376:SF275 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 41 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000012318.1|UniProtKB=W5N3E7 W5N3E7 PTHR48228:SF8 SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE ALPHA-METHYLACYL-COA RACEMASE racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;isomerase activity#GO:0016853 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;steroid metabolic process#GO:0008202;small molecule metabolic process#GO:0044281 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 Carnitine metabolism#P02733>Carnitine dehydratase#P02866;Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864 LEPOC|Ensembl=ENSLOCG00000018091.1|UniProtKB=W5NNI3 W5NNI3 PTHR24366:SF112 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS VASORIN B immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000014090.1|UniProtKB=W5N9Q1 W5N9Q1 PTHR34765:SF1 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 19 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 19 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000016260.1|UniProtKB=W5NHE6 W5NHE6 PTHR31918:SF2 TRANSMEMBRANE PROTEIN 181 TRANSMEMBRANE PROTEIN 181 positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of cell communication#GO:0010646;regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of establishment of protein localization#GO:0070201;regulation of protein localization#GO:0032880;regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of protein secretion#GO:0050714;regulation of transport#GO:0051049;regulation of localization#GO:0032879 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000013045.1|UniProtKB=W5N618 W5N618 PTHR24412:SF135 KELCH PROTEIN KELCH-LIKE PROTEIN 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000012880.1|UniProtKB=W5N5F2 W5N5F2 PTHR10957:SF3 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1-B-RELATED cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000007054.1|UniProtKB=W5MJH7 W5MJH7 PTHR11132:SF247 SOLUTE CARRIER FAMILY 35 NUCLEOTIDE SUGAR TRANSPORTER SLC35D1 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297 cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleotide-sugar transmembrane transport#GO:0015780;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003964.1|UniProtKB=W5M8M5 W5M8M5 PTHR14254:SF5 GENE 33 POLYPEPTIDE ERBB RECEPTOR FEEDBACK INHIBITOR 1 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of protein modification process#GO:0031399;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000018234.1|UniProtKB=W5NNX6 W5NNX6 PTHR22966:SF76 2-AMINOETHANETHIOL DIOXYGENASE 2-AMINOETHANETHIOL DIOXYGENASE oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 response to stimulus#GO:0050896;response to chemical#GO:0042221;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;cellular response to hypoxia#GO:0071456;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to hypoxia#GO:0001666;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000002041.1|UniProtKB=W5M1W4 W5M1W4 PTHR12422:SF2 GH09096P CYRIA_CYRIB RAC1 BINDING DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013014.1|UniProtKB=W5N5X6 W5N5X6 PTHR14647:SF57 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 4 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000009501.1|UniProtKB=W5MTA3 W5MTA3 PTHR46896:SF2 SENTRIN-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 7 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;post-translational protein modification#GO:0043687 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000006144.1|UniProtKB=W5MGB3 W5MGB3 PTHR21456:SF2 FAMILY WITH SEQUENCE SIMILARITY 102 EARLY ESTROGEN-INDUCED GENE 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000011955.1|UniProtKB=W5N239 W5N239 PTHR22923:SF64 CEREBELLIN-RELATED C1Q-RELATED FACTOR cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011046.1|UniProtKB=W5MYV6 W5MYV6 PTHR10846:SF41 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 2 monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804 inorganic ion homeostasis#GO:0098771;regulation of signaling#GO:0023051;calcium ion homeostasis#GO:0055074;positive regulation of synaptic transmission#GO:0050806;negative regulation of signaling#GO:0023057;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;negative regulation of cell communication#GO:0010648;positive regulation of signaling#GO:0023056;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;negative regulation of biological process#GO:0048519;chemical homeostasis#GO:0048878;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;regulation of trans-synaptic signaling#GO:0099177;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of cell communication#GO:0010646;metal ion transport#GO:0030001;homeostatic process#GO:0042592;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;negative regulation of cellular process#GO:0048523;regulation of synaptic plasticity#GO:0048167;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000011159.1|UniProtKB=W5MZA0 W5MZA0 PTHR23216:SF2 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010538.1|UniProtKB=W5MX05 W5MX05 PTHR23036:SF193 CYTOKINE RECEPTOR FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008109.1|UniProtKB=W5MN90 W5MN90 PTHR12899:SF23 39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL18M binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;RNA binding#GO:0003723 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;nucleic acid transport#GO:0050657;localization#GO:0051179;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000004268.1|UniProtKB=W5M9P1 W5M9P1 PTHR32205:SF4 ARCHAEMETZINCIN-2-RELATED ARCHAEMETZINCIN-1 LEPOC|Ensembl=ENSLOCG00000009164.1|UniProtKB=W5MS18 W5MS18 PTHR11599:SF11 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;proteasome complex#GO:0000502 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000015630.1|UniProtKB=W5NF37 W5NF37 PTHR11119:SF33 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 2 solute:sodium symporter activity#GO:0015370;carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;sugar transmembrane transporter activity#GO:0051119;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;carbohydrate transport#GO:0008643;carboxylic acid transmembrane transport#GO:1905039;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000003483.1|UniProtKB=W5M6X9 W5M6X9 PTHR24124:SF7 ANKYRIN REPEAT FAMILY A NF-KAPPA-B INHIBITOR DELTA regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000003056.1|UniProtKB=W5M5D4 W5M5D4 PTHR46970:SF1 BASIC HELIX-LOOP-HELIX DOMAIN-CONTAINING PROTEIN USF3 BASIC HELIX-LOOP-HELIX DOMAIN-CONTAINING PROTEIN USF3 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009050.1|UniProtKB=W5MRL4 W5MRL4 PTHR24340:SF32 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000002604.1|UniProtKB=W5M3W6 W5M3W6 PTHR11731:SF193 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 9 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000011982.1|UniProtKB=W5N284 W5N284 PTHR13429:SF11 FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY FERM DOMAIN-CONTAINING PROTEIN 6 protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 LEPOC|Ensembl=ENSLOCG00000012122.1|UniProtKB=W5N2Q5 W5N2Q5 PTHR14903:SF4 SCLEROSTIN-RELATED SCLEROSTIN binding#GO:0005488;cytokine binding#GO:0019955;protein binding#GO:0005515 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;ossification#GO:0001503;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of BMP signaling pathway#GO:0030514;regulation of BMP signaling pathway#GO:0030510;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;negative regulation of Wnt signaling pathway#GO:0030178 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003400.1|UniProtKB=W5M6L8 W5M6L8 PTHR23192:SF31 OLFACTOMEDIN-RELATED OLFACTOMEDIN-RELATED cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008325.1|UniProtKB=W5MP10 W5MP10 PTHR18945:SF23 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-5 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;channel activity#GO:0015267;molecular transducer activity#GO:0060089 transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;animal gross anatomical part developmental process#GO:0160108;synapse assembly#GO:0007416;signaling#GO:0023052;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;chloride transport#GO:0006821;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;nervous system development#GO:0007399;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;anatomical structure development#GO:0048856;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;system development#GO:0048731;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;multicellular organismal process#GO:0032501;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;neuron projection membrane#GO:0032589;signaling receptor complex#GO:0043235;cell junction#GO:0030054;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection membrane#GO:0031253 ligand-gated ion channel#PC00141 LEPOC|Ensembl=ENSLOCG00000004665.1|UniProtKB=W5MB27 W5MB27 PTHR12183:SF36 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 RING-TYPE E3 UBIQUITIN TRANSFERASE positive regulation of developmental process#GO:0051094;protein stabilization#GO:0050821;regulation of anatomical structure morphogenesis#GO:0022603;regulation of protein stability#GO:0031647;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of organelle organization#GO:0033043;positive regulation of mitochondrial fission#GO:0090141;regulation of mitochondrial fission#GO:0090140;regulation of developmental process#GO:0050793;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000002012.1|UniProtKB=W5M1Z9 W5M1Z9 PTHR23122:SF40 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PERIPHERAL PLASMA MEMBRANE PROTEIN CASK protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;regulation of secretion#GO:0051046;localization#GO:0051179;regulation of secretion by cell#GO:1903530;regulation of biological process#GO:0050789;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of localization#GO:0032879;intracellular protein localization#GO:0008104;regulation of transport#GO:0051049;macromolecule localization#GO:0033036;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Parkinson disease#P00049>CASK#P01232 LEPOC|Ensembl=ENSLOCG00000011239.1|UniProtKB=W5MZK4 W5MZK4 AK3 PTHR23359:SF68 NUCLEOTIDE KINASE GTP:AMP PHOSPHOTRANSFERASE AK3, MITOCHONDRIAL transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 LEPOC|Ensembl=ENSLOCG00000008803.1|UniProtKB=W5MQQ4 W5MQQ4 PTHR46907:SF1 HEAT SHOCK PROTEIN BETA-7-RELATED SHSP DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000010306.1|UniProtKB=W5MW70 W5MW70 PTHR23503:SF130 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;vitamin transport#GO:0051180 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000012559.1|UniProtKB=W5N4A4 W5N4A4 PTHR12478:SF18 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 DNA DAMAGE-INDUCIBLE TRANSCRIPT 4-LIKE PROTEIN-LIKE cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531 LEPOC|Ensembl=ENSLOCG00000013207.1|UniProtKB=W5N6K9 W5N6K9 PTHR15441:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P14 RIBONUCLEASE P PROTEIN SUBUNIT P14 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;endonuclease complex#GO:1905348;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000018085.1|UniProtKB=W5NNH7 W5NNH7 PTHR11214:SF291 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;aminoglycan biosynthetic process#GO:0006023;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000004132.1|UniProtKB=W5M980 W5M980 PTHR20859:SF85 INTERFERON/INTERLEUKIN RECEPTOR FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000017561.1|UniProtKB=W5NM07 W5NM07 PTHR24393:SF151 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 956 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000016486.1|UniProtKB=W5NIA7 W5NIA7 PTHR22969:SF14 IKB KINASE SERINE_THREONINE-PROTEIN KINASE TBK1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;immune system process#GO:0002376;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;positive regulation of response to external stimulus#GO:0032103;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to biotic stimulus#GO:0002831;positive regulation of type I interferon production#GO:0032481;positive regulation of biosynthetic process#GO:0009891;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;positive regulation of response to biotic stimulus#GO:0002833;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Toll receptor signaling pathway#P00054>TBK1#P01361 LEPOC|Ensembl=ENSLOCG00000011538.1|UniProtKB=W5N0L6 W5N0L6 PTHR10780:SF3 MITOCHONDRIAL CARRIER HOMOLOG MITOCHONDRIAL CARRIER HOMOLOG 1 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;positive regulation of programmed cell death#GO:0043068;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;protein localization to mitochondrion#GO:0070585;regulation of biological process#GO:0050789;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040;protein insertion into membrane#GO:0051205;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;membrane organization#GO:0061024;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;mitochondrial membrane organization#GO:0007006;positive regulation of cellular process#GO:0048522;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;positive regulation of apoptotic process#GO:0043065;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;regulation of apoptotic process#GO:0042981 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000007510.1|UniProtKB=W5ML52 W5ML52 PTHR45710:SF8 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN CONTAINING 5A-RELATED cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016740.1|UniProtKB=W5NJ82 W5NJ82 DNPH1 PTHR15364:SF0 2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1 5-HYDROXYMETHYL-DUMP N-HYDROLASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate catabolic process#GO:0046434 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000004738.1|UniProtKB=W5MBB8 W5MBB8 PTHR34605:SF3 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN MUCIN-2-LIKE ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000008584.1|UniProtKB=W5MPY4 W5MPY4 PTHR43107:SF7 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 1 ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;catalytic activity#GO:0003824;monocarboxylic acid transmembrane transporter activity#GO:0008028;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877 lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;macromolecule localization#GO:0033036;lipid transport#GO:0006869 cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000017102.1|UniProtKB=W5NKH4 W5NKH4 PTHR42884:SF23 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED ENDOPROTEASE AEX-5 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000010057.1|UniProtKB=W5MV91 W5MV91 PTHR16238:SF7 GEM-ASSOCIATED PROTEIN 8 GEM-ASSOCIATED PROTEIN 8 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;spliceosomal snRNP assembly#GO:0000387;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;SMN complex#GO:0032797;Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000006034.1|UniProtKB=W5MFX9 W5MFX9 PTHR11627:SF3 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE C lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;fructose-bisphosphate aldolase activity#GO:0004332;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nicotinamide nucleotide metabolic process#GO:0046496;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;primary metabolic process#GO:0044238;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 lyase#PC00144;aldolase#PC00044 Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959;Glycolysis#P00024>Aldolase#P00679 LEPOC|Ensembl=ENSLOCG00000009728.1|UniProtKB=W5MU19 W5MU19 PTHR10035:SF4 T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000003697.1|UniProtKB=W5M7P1 W5M7P1 PTHR24068:SF153 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 W ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824 proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001003.1|UniProtKB=W5LYC4 W5LYC4 PTHR12381:SF66 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010114.1|UniProtKB=W5MVG4 W5MVG4 PTHR24006:SF842 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 40 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 cysteine protease#PC00081;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000006141.1|UniProtKB=W5MGD3 W5MGD3 PTHR24348:SF19 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 reticulophagy#GO:0061709;axon development#GO:0061564;response to nutrient levels#GO:0031667;negative regulation of cell growth#GO:0030308;plasma membrane bounded cell projection organization#GO:0120036;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;developmental process#GO:0032502;cellular developmental process#GO:0048869;negative regulation of cellular component organization#GO:0051129;response to starvation#GO:0042594;regulation of growth#GO:0040008;catabolic process#GO:0009056;regulation of developmental process#GO:0050793;organelle assembly#GO:0070925;regulation of nervous system development#GO:0051960;vacuole organization#GO:0007033;system development#GO:0048731;response to stress#GO:0006950;autophagy#GO:0006914;regulation of cell growth#GO:0001558;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;metabolic process#GO:0008152;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell growth#GO:0016049;regulation of axonogenesis#GO:0050770;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;regulation of multicellular organismal development#GO:2000026;regulation of cellular component size#GO:0032535;cell projection organization#GO:0030030;cell differentiation#GO:0030154;generation of neurons#GO:0048699;regulation of cell size#GO:0008361;developmental growth involved in morphogenesis#GO:0060560;regulation of metabolic process#GO:0019222;regulation of cell development#GO:0060284;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of cell differentiation#GO:0045595;neuron projection morphogenesis#GO:0048812;developmental growth#GO:0048589;mitophagy#GO:0000423;regulation of plasma membrane bounded cell projection organization#GO:0120035;neurogenesis#GO:0022008;regulation of catabolic process#GO:0009894;regulation of neurogenesis#GO:0050767;negative regulation of multicellular organismal process#GO:0051241;regulation of cellular process#GO:0050794;piecemeal microautophagy of the nucleus#GO:0034727;developmental cell growth#GO:0048588;anatomical structure development#GO:0048856;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;autophagosome organization#GO:1905037;regulation of neuron projection development#GO:0010975;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;axon extension#GO:0048675;regulation of anatomical structure size#GO:0090066;growth#GO:0040007;neuron differentiation#GO:0030182;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron projection extension#GO:1990138;neuron development#GO:0048666;process utilizing autophagic mechanism#GO:0061919;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000002649.1|UniProtKB=W5M403 W5M403 PTHR45888:SF7 HL01030P-RELATED ZINC FINGER PROTEIN UBI-D4 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell differentiation#GO:0045595;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of developmental process#GO:0050793;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000003971.1|UniProtKB=W5M8N4 W5M8N4 PTHR10540:SF7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome complex#GO:0000502;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 LEPOC|Ensembl=ENSLOCG00000001292.1|UniProtKB=W5LZA9 W5LZA9 PTHR23060:SF3 TESTIS EXPRESSED GENE 14 INACTIVE SERINE_THREONINE-PROTEIN KINASE TEX14 regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;mitotic sister chromatid separation#GO:0051306;reproductive process#GO:0022414;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;localization#GO:0051179;cell communication#GO:0007154;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;negative regulation of chromosome organization#GO:2001251;organelle localization#GO:0051640;male gamete generation#GO:0048232;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;gamete generation#GO:0007276;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;extracellular structure organization#GO:0043062;negative regulation of mitotic sister chromatid separation#GO:2000816;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;chromosome localization#GO:0050000;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of cell cycle#GO:0045786;chromosome separation#GO:0051304;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid segregation#GO:0033047;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;meiotic nuclear division#GO:0140013;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;chromosome organization#GO:0051276;negative regulation of cellular process#GO:0048523;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of organelle organization#GO:0033043;nuclear division#GO:0000280;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;male meiotic nuclear division#GO:0007140;organelle organization#GO:0006996;negative regulation of sister chromatid segregation#GO:0033046;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of chromosome segregation#GO:0051985;meiotic cell cycle#GO:0051321;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048 midbody#GO:0030496;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000013808.1|UniProtKB=W5N8S0 W5N8S0 PTHR13016:SF0 AMMECR1 HOMOLOG AMME SYNDROME CANDIDATE GENE 1 PROTEIN LEPOC|Ensembl=ENSLOCG00000003223.1|UniProtKB=W5M5Z9 W5M5Z9 PTHR11414:SF21 CYSTATIN FAMILY MEMBER CYSTATIN 14B, TANDEM DUPLICATE 2-RELATED peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000001300.1|UniProtKB=W5LZD3 W5LZD3 PTHR34479:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 30 COILED-COIL DOMAIN-CONTAINING PROTEIN 30 LEPOC|Ensembl=ENSLOCG00000016773.1|UniProtKB=W5NJC5 W5NJC5 PTHR13049:SF2 DUF814-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 25 LEPOC|Ensembl=ENSLOCG00000015121.1|UniProtKB=W5NDA1 W5NDA1 PTHR24240:SF67 OPSIN TELEOST MULTIPLE TISSUE OPSIN 3A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;cellular response to radiation#GO:0071478;signaling#GO:0023052;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;signal transduction#GO:0007165;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;cellular process#GO:0009987;detection of stimulus#GO:0051606;biological regulation#GO:0065007;response to external stimulus#GO:0009605;cellular response to abiotic stimulus#GO:0071214 membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929;organelle#GO:0043226;photoreceptor outer segment#GO:0001750;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;9+0 non-motile cilium#GO:0097731;membrane#GO:0016020;neuron projection#GO:0043005;photoreceptor cell cilium#GO:0097733;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011586.1|UniProtKB=W5N0T3 W5N0T3 PTHR48083:SF42 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE FAMILY MEMBER 11 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000009020.1|UniProtKB=W5MRI4 W5MRI4 PTHR23291:SF78 BAX INHIBITOR-RELATED FAS APOPTOTIC INHIBITORY MOLECULE 2A monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085 endoplasmic reticulum unfolded protein response#GO:0030968;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of neuron apoptotic process#GO:0043524;response to stress#GO:0006950;regulation of neuron apoptotic process#GO:0043523;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;negative regulation of signal transduction#GO:0009968;regulation of apoptotic process#GO:0042981;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;negative regulation of cell communication#GO:0010648 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000013815.1|UniProtKB=W5N8T2 W5N8T2 PTHR19211:SF117 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3 ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;binding#GO:0005488;ATP binding#GO:0005524;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 translation elongation factor#PC00222 LEPOC|Ensembl=ENSLOCG00000012269.1|UniProtKB=W5N390 W5N390 PTHR14002:SF13 ENDOGLIN/TGF-BETA RECEPTOR TYPE III BETA-TECTORIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009755.1|UniProtKB=W5MU53 W5MU53 PTHR11461:SF375 SERINE PROTEASE INHIBITOR, SERPIN THYROXINE-BINDING GLOBULIN enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000011926.1|UniProtKB=W5N200 W5N200 PTHR16705:SF7 COMPLEXIN COMPLEXIN-4 SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515 neurotransmitter transport#GO:0006836;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;synaptic signaling#GO:0099536;regulation of transport#GO:0051049;regulation of localization#GO:0032879;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055;export from cell#GO:0140352;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;secretion by cell#GO:0032940;cellular localization#GO:0051641;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537 cellular anatomical structure#GO:0110165;synapse#GO:0045202;SNARE complex#GO:0031201;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuron projection terminus#GO:0044306;cell projection#GO:0042995;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;axon#GO:0030424;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;presynapse#GO:0098793;neuron projection#GO:0043005;cell junction#GO:0030054;axon terminus#GO:0043679 LEPOC|Ensembl=ENSLOCG00000011716.1|UniProtKB=W5N1A4 W5N1A4 PTHR11347:SF191 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585 phosphodiesterase#PC00185;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000011325.1|UniProtKB=W5MZW3 W5MZW3 PTHR11492:SF4 NUCLEAR FACTOR I NUCLEAR FACTOR 1 B-TYPE cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009018.1|UniProtKB=W5MRI8 W5MRI8 PTHR23511:SF11 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2A anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;signaling#GO:0023052;export from cell#GO:0140352;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular localization#GO:0051641;secretion by cell#GO:0032940;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;regulated exocytosis#GO:0045055;exocytic process#GO:0140029 intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793;neuron projection#GO:0043005;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasm#GO:0005737;cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 LEPOC|Ensembl=ENSLOCG00000006384.1|UniProtKB=W5MH51 W5MH51 PTHR24115:SF372 KINESIN-RELATED KINESIN-LIKE PROTEIN polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule binding#GO:0008017;microtubule motor activity#GO:0003777;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;plus-end-directed microtubule motor activity#GO:0008574;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774 organelle localization#GO:0051640;nuclear division#GO:0000280;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cellular component disassembly#GO:0022411;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;protein-containing complex disassembly#GO:0032984;mitotic cell cycle#GO:0000278;microtubule-based movement#GO:0007018;chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;chromosome localization#GO:0050000;protein depolymerization#GO:0051261;microtubule depolymerization#GO:0007019 cytoplasmic microtubule#GO:0005881;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;spindle#GO:0005819;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000017369.1|UniProtKB=W5NLG5 W5NLG5 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002925.1|UniProtKB=W5M511 W5M511 PTHR19237:SF22 NUCLEOBINDIN NUCLEOBINDIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000013263.1|UniProtKB=W5N6T0 W5N6T0 PTHR15907:SF186 DUF614 FAMILY PROTEIN-RELATED PLACENTA-SPECIFIC GENE 8 PROTEIN ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000001250.1|UniProtKB=W5LZ66 W5LZ66 KYNU PTHR14084:SF0 KYNURENINASE KYNURENINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000012578.1|UniProtKB=W5N4C3 W5N4C3 PTHR11964:SF11 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 nucleotidyltransferase#PC00174;transferase#PC00220 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 LEPOC|Ensembl=ENSLOCG00000015220.1|UniProtKB=W5NDM5 W5NDM5 PTHR11475:SF63 OXIDASE/PEROXIDASE EOSINOPHIL PEROXIDASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000008194.1|UniProtKB=W5MNI8 W5MNI8 PTHR45710:SF8 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN CONTAINING 5A-RELATED biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000012229.1|UniProtKB=W5N356 W5N356 PTHR11850:SF47 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS2 sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216 positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;sensory system development#GO:0048880;embryonic pattern specification#GO:0009880;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;head development#GO:0060322;nervous system development#GO:0007399;embryo development#GO:0009790;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;eye development#GO:0001654;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000016778.1|UniProtKB=W5NJC9 W5NJC9 PTHR23157:SF25 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000005602.1|UniProtKB=W5MEF4 W5MEF4 PTHR46745:SF1 TSC22 DOMAIN FAMILY PROTEIN 1 TSC22 DOMAIN FAMILY PROTEIN 1 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of cell population proliferation#GO:0042127;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;positive regulation of cell population proliferation#GO:0008284;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000009986.1|UniProtKB=W5MV03 W5MV03 PTHR28546:SF3 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 biological regulation#GO:0065007;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;macromolecule metabolic process#GO:0043170;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;regulation of biological quality#GO:0065008;protein transport#GO:0015031;metabolic process#GO:0008152;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;transport#GO:0006810 synaptic membrane#GO:0097060;cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;late endosome#GO:0005770;glutamatergic synapse#GO:0098978;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;endosome#GO:0005768;postsynaptic membrane#GO:0045211;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202 LEPOC|Ensembl=ENSLOCG00000010897.1|UniProtKB=W5MYA1 W5MYA1 PTHR11394:SF72 TASTE RECEPTOR TYPE 2 OLFACTORY RECEPTOR CLASS A-LIKE PROTEIN 4 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009194.1|UniProtKB=W5MS60 W5MS60 PTHR24020:SF15 COLLAGEN ALPHA COLLAGEN ALPHA-1(XIV) CHAIN cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165;interstitial matrix#GO:0005614 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 LEPOC|Ensembl=ENSLOCG00000007958.1|UniProtKB=W5MMQ7 W5MMQ7 PTHR12281:SF31 RP42 RELATED DCN1-LIKE PROTEIN 3 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein binding#GO:0005515;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 regulation of protein modification process#GO:0031399;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000007642.1|UniProtKB=W5MLL2 W5MLL2 PTHR46805:SF3 FORKHEAD BOX PROTEIN J1 FORKHEAD BOX PROTEIN J1-B cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000005921.1|UniProtKB=W5MFJ1 W5MFJ1 PTHR33820:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 LEPOC|Ensembl=ENSLOCG00000009121.1|UniProtKB=W5MRW3 W5MRW3 PTHR13126:SF0 CHAPERONE ATP11 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1 mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000009009.1|UniProtKB=W5MRH0 W5MRH0 PTHR24034:SF200 EGF-LIKE DOMAIN-CONTAINING PROTEIN FI18763P1-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000004151.1|UniProtKB=W5M9B2 W5M9B2 PTHR14002:SF59 ENDOGLIN/TGF-BETA RECEPTOR TYPE III CUB AND ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000016326.1|UniProtKB=W5NHP8 W5NHP8 PTHR11109:SF6 GTP CYCLOHYDROLASE I GTP CYCLOHYDROLASE 1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;biosynthetic process#GO:0009058;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 Tetrahydrofolate biosynthesis#P02742>GTP cyclohydrolase#P02951 LEPOC|Ensembl=ENSLOCG00000014287.1|UniProtKB=W5NAD6 W5NAD6 PTHR12354:SF8 INTERFERON-RELATED DEVELOPMENTAL REGULATOR INTERFERON-RELATED DEVELOPMENTAL REGULATOR 2 LEPOC|Ensembl=ENSLOCG00000005422.1|UniProtKB=W5MDT4 W5MDT4 PTHR45616:SF21 GATA-TYPE DOMAIN-CONTAINING PROTEIN KERATIN, TYPE II CYTOSKELETAL 7 structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;intermediate filament-based process#GO:0045103;keratinocyte differentiation#GO:0030216;animal gross anatomical part developmental process#GO:0160108;intermediate filament organization#GO:0045109;intermediate filament cytoskeleton organization#GO:0045104;cell differentiation#GO:0030154;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;animal organ development#GO:0048513;epidermis development#GO:0008544;developmental process#GO:0032502;epithelium development#GO:0060429;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;skin development#GO:0043588;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 LEPOC|Ensembl=ENSLOCG00000004219.1|UniProtKB=W5M9I2 W5M9I2 PTHR14002:SF59 ENDOGLIN/TGF-BETA RECEPTOR TYPE III CUB AND ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010688.1|UniProtKB=W5MXI0 W5MXI0 PTHR20957:SF0 RNA-BINDING PROTEIN 48 RNA-BINDING PROTEIN 48 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;catalytic step 2 spliceosome#GO:0071013;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000001353.1|UniProtKB=W5LZL8 W5LZL8 PTHR45990:SF1 DNA REPAIR PROTEIN REV1 TRANSLESION SYNTHESIS PROTEIN REV1 DNA-directed DNA polymerase activity#GO:0003887;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097 response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA synthesis involved in DNA replication#GO:0090592 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008631.1|UniProtKB=W5MQ32 W5MQ32 PTHR10903:SF199 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017115.1|UniProtKB=W5NKJ0 W5NKJ0 PTHR22802:SF460 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009011.1|UniProtKB=W5MRH5 W5MRH5 PTHR46920:SF1 FAMILY NOT NAMED PROTEIN MSS51 HOMOLOG, MITOCHONDRIAL-RELATED LEPOC|Ensembl=ENSLOCG00000001234.1|UniProtKB=W5LZ40 W5LZ40 PTHR13091:SF0 AMPLIFIED IN BREAST CANCER 2-RELATED NONSENSE-MEDIATED MRNA DECAY FACTOR SMG8 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468 LEPOC|Ensembl=ENSLOCG00000013424.1|UniProtKB=W5N7E6 W5N7E6 PTHR11461:SF290 SERINE PROTEASE INHIBITOR, SERPIN SERINE (OR CYSTEINE) PEPTIDASE INHIBITOR, CLADE H, MEMBER 2 ISOFORM X1 molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 external encapsulating structure organization#GO:0045229;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000012039.1|UniProtKB=W5N2E8 W5N2E8 PTHR10903:SF167 GTPASE, IMAP FAMILY MEMBER-RELATED SI:DKEYP-69E1.8 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017918.1|UniProtKB=W5NN12 W5NN12 PTHR24248:SF117 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013341.1|UniProtKB=W5N734 W5N734 PTHR47368:SF5 NUMB PROTEIN NUMB HOMOLOG positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;biological regulation#GO:0065007;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;positive regulation of nervous system development#GO:0051962;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;basal part of cell#GO:0045178;vesicle#GO:0031982;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;cytoplasm#GO:0005737;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 Notch signaling pathway#P00045>Numb#P01118 LEPOC|Ensembl=ENSLOCG00000004667.1|UniProtKB=W5MB30 W5MB30 PTHR10379:SF6 MTG8 ETO EIGHT TWENTY ONE PROTEIN TRANSCRIPTIONAL COREPRESSOR CBFA2T3 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000008831.1|UniProtKB=W5MQU6 W5MQU6 PTHR24043:SF9 SCAVENGER RECEPTOR CLASS F MULTIPLE EGF LIKE DOMAINS 11 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012274.1|UniProtKB=W5N395 W5N395 PTHR24073:SF471 DRAB5-RELATED RAS-RELATED PROTEIN RAB-24 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;autophagosome#GO:0005776;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227 small GTPase#PC00208;G-protein#PC00020 LEPOC|Ensembl=ENSLOCG00000003999.1|UniProtKB=W5M8U8 W5M8U8 PTHR23042:SF52 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS BASIC HELIX-LOOP-HELIX ARNT-LIKE PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;circadian rhythm#GO:0007623;rhythmic process#GO:0048511;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 Circadian clock system#P00015>bmal1#G01504;Hypoxia response via HIF activation#P00030>HIF-1beta#P00820;Circadian clock system#P00015>BMAL1#P00506;Circadian clock system#P00015>bmal1#G01500 LEPOC|Ensembl=ENSLOCG00000013786.1|UniProtKB=W5N8P1 W5N8P1 PTHR10676:SF359 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN DOMAIN-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;microtubule motor activity#GO:0003777 cilium or flagellum-dependent cell motility#GO:0001539;cilium movement#GO:0003341;cilium-dependent cell motility#GO:0060285;microtubule-based process#GO:0007017;cilium movement involved in cell motility#GO:0060294;cellular process#GO:0009987;cell motility#GO:0048870;microtubule-based movement#GO:0007018 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;9+2 motile cilium#GO:0097729;cilium#GO:0005929;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;motile cilium#GO:0031514;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;dynein complex#GO:0030286;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000002305.1|UniProtKB=W5M2U0 W5M2U0 PTHR11360:SF255 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 13 monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012484.1|UniProtKB=W5N407 W5N407 PTHR24214:SF9 PDZ AND LIM DOMAIN PROTEIN ZASP LIM DOMAIN-BINDING PROTEIN 3 binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;heart development#GO:0007507;multicellular organismal process#GO:0032501;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;circulatory system development#GO:0072359;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;actomyosin#GO:0042641;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;cell-cell junction#GO:0005911;adherens junction#GO:0005912;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;sarcomere#GO:0030017;actin filament#GO:0005884;I band#GO:0031674;cytoskeleton#GO:0005856;stress fiber#GO:0001725;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006233.1|UniProtKB=W5MGM1 W5MGM1 PTHR10050:SF51 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 1 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000004741.1|UniProtKB=W5MBC7 W5MBC7 PTHR24225:SF81 CHEMOTACTIC RECEPTOR CHEMERIN-LIKE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;signaling#GO:0023052;immune response-activating cell surface receptor signaling pathway#GO:0002429;G protein-coupled receptor signaling pathway#GO:0007186;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of immune response#GO:0050776;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;regulation of biological quality#GO:0065008;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of immune response#GO:0050778;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;immune response-activating signaling pathway#GO:0002757 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004348.1|UniProtKB=W5M9Y8 W5M9Y8 PTHR15507:SF18 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN RLF DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000011319.1|UniProtKB=W5MZV9 W5MZV9 PTHR23355:SF35 RIBONUCLEASE EXOSOME COMPLEX EXONUCLEASE RRP44 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000015978.1|UniProtKB=W5NGB4 W5NGB4 PTHR10188:SF8 L-ASPARAGINASE THREONINE ASPARTASE 1 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001807.1|UniProtKB=W5M156 W5M156 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;hexose metabolic process#GO:0019318;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 glycosidase#PC00110;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000014161.1|UniProtKB=W5N9Y5 W5N9Y5 PTHR11937:SF13 ACTIN ACTIN-RELATED PROTEIN 8 mRNA binding#GO:0003729;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 regulation of gene expression#GO:0010468;double-strand break repair#GO:0006302;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular response to stress#GO:0033554;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 Ino80 complex#GO:0031011;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 actin and actin related protein#PC00039 LEPOC|Ensembl=ENSLOCG00000006483.1|UniProtKB=W5MHG9 W5MHG9 PTHR31185:SF0 FIN BUD INITIATION FACTOR FIBIN FIN BUD INITIATION FACTOR HOMOLOG LEPOC|Ensembl=ENSLOCG00000007092.1|UniProtKB=W5MJM9 W5MJM9 PTHR11211:SF47 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS HOMEOBOX 6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;cell development#GO:0048468;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000004649.1|UniProtKB=W5MB10 W5MB10 PTHR12628:SF12 POLYCOMB-LIKE TRANSCRIPTION FACTOR METAL-RESPONSE ELEMENT-BINDING TRANSCRIPTION FACTOR 2 DNA binding#GO:0003677;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000009497.1|UniProtKB=W5MT86 W5MT86 PTHR47084:SF1 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT A SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT A transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;ceramide metabolic process#GO:0006672 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000017793.1|UniProtKB=W5NMN8 W5NMN8 PTHR23186:SF3 RETINOIC ACID-INDUCED PROTEIN 2 RETINOIC ACID-INDUCED PROTEIN 2 anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015649.1|UniProtKB=W5NF55 W5NF55 PTHR10127:SF870 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING ALVEOLIN metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000008266.1|UniProtKB=W5MNS4 W5MNS4 PTHR23235:SF145 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUPPEL-LIKE FACTOR 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000013342.1|UniProtKB=W5N750 W5N750 PTHR13373:SF21 FROUNT PROTEIN-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP85 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 gene expression#GO:0010467;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;protein transport#GO:0015031;protein import into nucleus#GO:0006606;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear pore outer ring#GO:0031080;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000003174.1|UniProtKB=W5M5V4 W5M5V4 PTHR11922:SF6 GMP SYNTHASE-RELATED GMP SYNTHASE [GLUTAMINE-HYDROLYZING] ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ligase#PC00142 De novo purine biosynthesis#P02738>GMP synthase#P02899 LEPOC|Ensembl=ENSLOCG00000003916.1|UniProtKB=W5M8H4 W5M8H4 PTHR18934:SF234 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX40-RELATED helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 RNA metabolism protein#PC00031;RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000012429.1|UniProtKB=W5N3U1 W5N3U1 PTHR46990:SF2 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 1 GLUTAREDOXIN AND CYSTEINE-RICH DOMAIN-CONTAINING 1 B-RELATED oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000001550.1|UniProtKB=W5M070 W5M070 PTHR12454:SF3 TRIMERIC INTRACELLULAR CATION CHANNEL TRIMERIC INTRACELLULAR CATION CHANNEL TYPE A transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;potassium channel activity#GO:0005267;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;release of sequestered calcium ion into cytosol by sarcoplasmic reticulum#GO:0014808;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017;cytoplasm#GO:0005737;membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;sarcoplasm#GO:0016528;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000008589.1|UniProtKB=W5MPY5 W5MPY5 PTHR46645:SF2 GRAM DOMAIN-CONTAINING PROTEIN 2B-RELATED GRAM DOMAIN-CONTAINING PROTEIN 2B microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 LEPOC|Ensembl=ENSLOCG00000016485.1|UniProtKB=W5NIA5 W5NIA5 PTHR10272:SF0 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000009942.1|UniProtKB=W5MUV0 W5MUV0 PTHR16487:SF0 PPP4R2-RELATED PROTEIN SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2 phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000013569.1|UniProtKB=W5N7X0 W5N7X0 PTHR24215:SF29 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE-RICH PROTEIN 2 cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000000874.1|UniProtKB=W5LXW5 W5LXW5 PTHR24377:SF1040 IP01015P-RELATED ZINC FINGER PROTEIN 467 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000008612.1|UniProtKB=W5MQ08 W5MQ08 PTHR15249:SF0 TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR Toll receptor signaling pathway#P00054>TANK#P01353 LEPOC|Ensembl=ENSLOCG00000001635.1|UniProtKB=W5M0H3 W5M0H3 PTHR18945:SF401 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4 excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;acetylcholine receptor activity#GO:0015464;monoatomic cation transmembrane transporter activity#GO:0008324 trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;response to nitrogen compound#GO:1901698;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;membrane depolarization#GO:0051899;modulation of chemical synaptic transmission#GO:0050804;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;neuromuscular synaptic transmission#GO:0007274;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;regulation of trans-synaptic signaling#GO:0099177;response to chemical#GO:0042221 transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA4#P06594;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 LEPOC|Ensembl=ENSLOCG00000011805.1|UniProtKB=W5N1K8 W5N1K8 PTHR23167:SF89 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED MICAL-LIKE PROTEIN 1 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>alpha actinin#P00928 LEPOC|Ensembl=ENSLOCG00000014039.1|UniProtKB=W5N9J8 W5N9J8 PTHR24034:SF158 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN 2 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000012624.1|UniProtKB=W5N4H9 W5N4H9 LEMD2 PTHR13428:SF8 INNER NUCLEAR MEMBRANE PROTEIN MAN1 LEM DOMAIN CONTAINING PROTEIN LEM DOMAIN-CONTAINING PROTEIN 2 chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 nuclear envelope organization#GO:0006998;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;membrane assembly#GO:0071709;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967 LEPOC|Ensembl=ENSLOCG00000007305.1|UniProtKB=W5MKD6 W5MKD6 PTHR34757:SF1 JUNCTIONAL PROTEIN ASSOCIATED WITH CORONARY ARTERY DISEASE JUNCTIONAL CADHERIN 5-ASSOCIATED PROTEIN positive regulation of cell population proliferation#GO:0008284;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cell population proliferation#GO:0042127 ruffle membrane#GO:0032587;adherens junction#GO:0005912;ruffle#GO:0001726;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;cell leading edge#GO:0031252;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;leading edge membrane#GO:0031256;anchoring junction#GO:0070161;cell projection membrane#GO:0031253;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000005004.1|UniProtKB=W5MCC4 W5MCC4 PTHR11566:SF67 DYNAMIN DYNAMIN-LIKE GTPASE OPA1, MITOCHONDRIAL hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515 cellular component organization#GO:0016043;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fusion#GO:0048284;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;microtubule cytoskeleton#GO:0015630;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;cytoskeleton#GO:0005856;mitochondrial intermembrane space#GO:0005758;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrion#GO:0005739;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000001521.1|UniProtKB=W5M032 W5M032 PTHR13170:SF23 O-GLCNACASE PROTEIN O-GLCNACASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;metabolic process#GO:0008152 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000015078.1|UniProtKB=W5ND46 W5ND46 PTHR10367:SF9 MRNA-CAPPING ENZYME RNA_RNP COMPLEX-1-INTERACTING PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 RNA processing factor#PC00147;mRNA capping factor#PC00145 LEPOC|Ensembl=ENSLOCG00000011811.1|UniProtKB=W5N1M7 W5N1M7 PTHR45652:SF9 GLIAL FIBRILLARY ACIDIC PROTEIN GLIAL FIBRILLARY ACIDIC PROTEIN structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;intermediate filament cytoskeleton organization#GO:0045104;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of autophagy#GO:0010506;regulation of protein catabolic process#GO:0042176;supramolecular fiber organization#GO:0097435;intermediate filament organization#GO:0045109;intermediate filament-based process#GO:0045103;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000007768.1|UniProtKB=W5MM23 W5MM23 PTHR24126:SF53 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED CYCLIN-DEPENDENT KINASE 4 INHIBITOR D protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297;transcription factor binding#GO:0008134;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000001372.1|UniProtKB=W5LZL0 W5LZL0 PTHR12969:SF7 NGD5/OSM-6/IFT52 INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810 membraneless organelle#GO:0043228;intraciliary transport particle B#GO:0030992;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000015838.1|UniProtKB=W5NFT9 W5NFT9 PTHR10306:SF33 SYNAPTOPHYSIN SYNAPTOPHYSIN-LIKE 1 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013373.1|UniProtKB=W5N777 W5N777 PTHR13363:SF5 RING FINGER AND SRY DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF123 ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000004125.1|UniProtKB=W5M977 W5M977 PTHR11616:SF129 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER serotonin binding#GO:0051378;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;symporter activity#GO:0015293;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;solute:sodium symporter activity#GO:0015370;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;chloride transmembrane transporter activity#GO:0015108;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857 monoatomic cation transmembrane transport#GO:0098655;neurotransmitter transport#GO:0006836;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;amino acid transport#GO:0006865;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;organic hydroxy compound transport#GO:0015850;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000009397.1|UniProtKB=W5MSW9 W5MSW9 PTHR10048:SF7 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 cellular component assembly#GO:0022607;glycerophospholipid metabolic process#GO:0006650;autophagy#GO:0006914;signal transduction#GO:0007165;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;metabolic process#GO:0008152;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;endocytosis#GO:0006897;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;phosphatidylinositol phosphate biosynthetic process#GO:0046854;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macroautophagy#GO:0016236;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;pexophagy#GO:0000425;establishment of localization#GO:0051234;glycerophospholipid biosynthetic process#GO:0046474;transport#GO:0006810;lipid metabolic process#GO:0006629;phospholipid metabolic process#GO:0006644;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;vacuole organization#GO:0007033;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;organelle assembly#GO:0070925 membrane#GO:0016020;microbody#GO:0042579;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;extrinsic component of membrane#GO:0019898;peroxisome#GO:0005777;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;phosphatidylinositol 3-kinase complex, class III#GO:0035032;endosome#GO:0005768;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase#PC00137 p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Angiogenesis#P00005>PI3K#P00236;PDGF signaling pathway#P00047>PI3K#P01168;Ras Pathway#P04393>PI3K#P04567;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;EGF receptor signaling pathway#P00018>PI3K#P00557;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;T cell activation#P00053>PI3K#P01322;VEGF signaling pathway#P00056>PI3K#P01413;Integrin signalling pathway#P00034>PI3K#P00936 LEPOC|Ensembl=ENSLOCG00000007417.1|UniProtKB=W5MKW0 W5MKW0 PTHR14043:SF5 CCAAT DISPLACEMENT PROTEIN-RELATED HOMEOBOX PROTEIN CUT-LIKE 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000003898.1|UniProtKB=W5M8G4 W5M8G4 PTHR48041:SF75 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 4 transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 transmembrane transport#GO:0055085;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;sterol transport#GO:0015918;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;chemical homeostasis#GO:0048878;transport#GO:0006810;lipid transport#GO:0006869;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cellular process#GO:0009987;cholesterol efflux#GO:0033344 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000016600.1|UniProtKB=W5NIQ6 W5NIQ6 PTHR31344:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP205 NUCLEAR PORE COMPLEX PROTEIN NUP205 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;nuclear pore organization#GO:0006999;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000011534.1|UniProtKB=W5N0L7 W5N0L7 PTHR45899:SF4 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 molecular function activator activity#GO:0140677;lipid binding#GO:0008289;enzyme regulator activity#GO:0030234;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;molecular function regulator activity#GO:0098772;phosphatidylinositol phosphate binding#GO:1901981;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047 regulation of actin filament-based process#GO:0032970;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000004954.1|UniProtKB=W5MC45 W5MC45 PTHR13232:SF12 NAD(P)H-HYDRATE EPIMERASE YJEF N-TERMINAL DOMAIN-CONTAINING PROTEIN 3 isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;epimerase/racemase#PC00096 LEPOC|Ensembl=ENSLOCG00000016161.1|UniProtKB=W5NH04 W5NH04 PTHR46238:SF8 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000002809.1|UniProtKB=W5M4K5 W5M4K5 PTHR11062:SF381 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-2 catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;glycosyltransferase#PC00111 LEPOC|Ensembl=ENSLOCG00000009848.1|UniProtKB=W5MUH9 W5MUH9 PTHR11481:SF112 IMMUNOGLOBULIN FC RECEPTOR BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;immune response#GO:0006955;signal transduction#GO:0007165;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;immune system process#GO:0002376 plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002297.1|UniProtKB=W5M2V9 W5M2V9 PTHR47966:SF42 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CATHEPSIN D catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosome#GO:0005764 protease#PC00190;aspartic protease#PC00053 LEPOC|Ensembl=ENSLOCG00000002266.1|UniProtKB=W5M2R3 W5M2R3 PTHR24291:SF120 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;vitamin D metabolic process#GO:0042359;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000010634.1|UniProtKB=W5MXB5 W5MXB5 PTHR19918:SF35 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG binding#GO:0005488;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;proteasomal protein catabolic process#GO:0010498;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;protein metabolic process#GO:0019538;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255 ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000016367.1|UniProtKB=W5NHV1 W5NHV1 PTHR23179:SF26 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED T-CELL ACTIVATION RHO GTPASE-ACTIVATING PROTEIN enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 LEPOC|Ensembl=ENSLOCG00000005561.1|UniProtKB=W5MEA9 W5MEA9 PTHR13309:SF0 NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1 FMR1-INTERACTING PROTEIN NUFIP1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex assembly#GO:0022618;protein-RNA complex organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;cellular component assembly#GO:0022607 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001691.1|UniProtKB=W5M0P1 W5M0P1 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune system process#GO:0002376;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;antigen receptor-mediated signaling pathway#GO:0050851;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013369.1|UniProtKB=W5N766 W5N766 PTHR47004:SF1 F-BOX ONLY PROTEIN 24 F-BOX ONLY PROTEIN 24 LEPOC|Ensembl=ENSLOCG00000007749.1|UniProtKB=W5MM05 W5MM05 PTHR22809:SF3 METHYLTRANSFERASE-RELATED TRNA N(3)-CYTIDINE METHYLTRANSFERASE METTL8, MITOCHONDRIAL RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 methyltransferase#PC00155 LEPOC|Ensembl=ENSLOCG00000010577.1|UniProtKB=W5MX54 W5MX54 PTHR13134:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 TRAPP complex#GO:0030008;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 LEPOC|Ensembl=ENSLOCG00000001259.1|UniProtKB=W5LZ76 W5LZ76 PTHR11328:SF50 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 12 neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;localization#GO:0051179;pigmentation#GO:0043473;regulation of cellular process#GO:0050794;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;metabolic process#GO:0008152;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;biological regulation#GO:0065007;nitrogen compound transport#GO:0071705;regulation of metabolic process#GO:0019222;pigment metabolic process#GO:0042440;L-amino acid transport#GO:0015807;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000014238.1|UniProtKB=W5NA73 W5NA73 PTHR10174:SF200 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED RETINALDEHYDE-BINDING PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000006732.1|UniProtKB=W5MIC5 W5MIC5 PTHR11932:SF76 CULLIN CULLIN-5 protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;structural molecule activity#GO:0005198;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein complex scaffold activity#GO:0140378 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;Cul5-RING ubiquitin ligase complex#GO:0031466;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000013182.1|UniProtKB=W5N6H7 W5N6H7 PTHR14484:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 LEPOC|Ensembl=ENSLOCG00000010516.1|UniProtKB=W5MWX7 W5MWX7 PTHR43671:SF104 SERINE/THREONINE-PROTEIN KINASE NEK SI:CH211-285C6.2-RELATED catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000016400.1|UniProtKB=W5NHZ3 W5NHZ3 PTHR31893:SF4 TRANSMEMBRANE PROTEIN 151 HOMOLOG TRANSMEMBRANE PROTEIN 151B membrane#GO:0016020;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000007852.1|UniProtKB=W5MMC3 W5MMC3 PTHR11442:SF7 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT BETA-RELATED binding#GO:0005488;molecular carrier activity#GO:0140104;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 multicellular organismal process#GO:0032501;hemopoiesis#GO:0030097;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;multicellular organismal-level homeostasis#GO:0048871;developmental process#GO:0032502;transport#GO:0006810;cell differentiation#GO:0030154;myeloid cell differentiation#GO:0030099;homeostatic process#GO:0042592;cell development#GO:0048468;localization#GO:0051179;anatomical structure development#GO:0048856;erythrocyte differentiation#GO:0030218;immune system process#GO:0002376;homeostasis of number of cells#GO:0048872 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219;globin#PC00107 LEPOC|Ensembl=ENSLOCG00000011515.1|UniProtKB=W5N0I8 W5N0I8 PTHR31774:SF14 PROTEIN SHISA-9-RELATED PROTEIN SHISA-8 regulation of biological quality#GO:0065008;regulation of neuronal synaptic plasticity#GO:0048168;regulation of signaling#GO:0023051;regulation of synaptic plasticity#GO:0048167;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of biological process#GO:0050789 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;asymmetric synapse#GO:0032279;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;neuron to neuron synapse#GO:0098984;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589;postsynapse#GO:0098794;dendritic spine#GO:0043197;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuron spine#GO:0044309;postsynaptic membrane#GO:0045211;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell leading edge#GO:0031252;neuron projection#GO:0043005;protein-containing complex#GO:0032991;synaptic membrane#GO:0097060;cell junction#GO:0030054;transporter complex#GO:1990351 LEPOC|Ensembl=ENSLOCG00000017518.1|UniProtKB=W5NLW4 W5NLW4 PTHR19290:SF83 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000010252.1|UniProtKB=W5MVZ9 W5MVZ9 PTHR10373:SF33 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of DNA-templated transcription#GO:0006355 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;chromatin#GO:0000785 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Gonadotropin-releasing hormone receptor pathway#P06664>TCF#P06701;Angiogenesis#P00005>TCF#P00242 LEPOC|Ensembl=ENSLOCG00000002657.1|UniProtKB=W5M443 W5M443 PTHR22928:SF4 TELOMERE-ASSOCIATED PROTEIN RIF1 TELOMERE-ASSOCIATED PROTEIN RIF1 organelle organization#GO:0006996;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723 membraneless organelle#GO:0043228;chromosome, telomeric repeat region#GO:0140445;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781;chromosome#GO:0005694;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000017144.1|UniProtKB=W5NKM8 W5NKM8 PTHR11949:SF1 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 Toll receptor signaling pathway#P00054>IRF3#P01374 LEPOC|Ensembl=ENSLOCG00000015672.1|UniProtKB=W5NF82 W5NF82 PTHR45652:SF8 GLIAL FIBRILLARY ACIDIC PROTEIN NEUROFILAMENT LIGHT POLYPEPTIDE structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918;structural constituent of cytoskeleton#GO:0005200 supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;intermediate filament organization#GO:0045109;intermediate filament bundle assembly#GO:0045110;intermediate filament-based process#GO:0045103;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;intermediate filament cytoskeleton organization#GO:0045104;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 axon#GO:0030424;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;postsynapse#GO:0098794;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054;neuron projection#GO:0043005;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085;intermediate filament#PC00129 LEPOC|Ensembl=ENSLOCG00000013884.1|UniProtKB=W5N912 W5N912 PTHR10980:SF9 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 1 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000005351.1|UniProtKB=W5MDI9 W5MDI9 PTHR12027:SF94 WNT RELATED PROTEIN WNT-8B receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell fate commitment#GO:0045165;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 LEPOC|Ensembl=ENSLOCG00000011197.1|UniProtKB=W5MZF4 W5MZF4 PTHR37456:SF3 SI:CH211-266K2.1 COLLAGEN ALPHA-1(XXV) CHAIN binding#GO:0005488;peptide binding#GO:0042277 LEPOC|Ensembl=ENSLOCG00000001568.1|UniProtKB=W5M088 W5M088 PTHR24034:SF146 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-7 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000008433.1|UniProtKB=W5MPE4 W5MPE4 PTHR46890:SF1 NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED SECRETED RXLR EFFECTOR PROTEIN 78-LIKE reverse transcriptase#PC00200;viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000009601.1|UniProtKB=W5MTM9 W5MTM9 PTHR12616:SF16 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 vesicle organization#GO:0016050;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;organelle membrane fusion#GO:0090174;vesicle fusion#GO:0006906;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;cellular component organization#GO:0016043;membrane fusion#GO:0061025;organelle organization#GO:0006996 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;vesicle tethering complex#GO:0099023;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000006701.1|UniProtKB=W5MI85 W5MI85 PTHR11594:SF1 40S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN ES27 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;translation#GO:0006412;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;protein biosynthetic process#GO:0160307 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000004739.1|UniProtKB=W5MBG7 W5MBG7 PTHR10985:SF104 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-5 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cell communication#GO:0007154;pattern specification process#GO:0007389;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;Notch signaling pathway#GO:0007219;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of multicellular organismal process#GO:0051239;nervous system development#GO:0007399;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;anterior/posterior pattern specification#GO:0009952 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000002308.1|UniProtKB=W5M2U3 W5M2U3 PTHR24068:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;protein modification by small protein conjugation or removal#GO:0070647;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Ubc6#P01222 LEPOC|Ensembl=ENSLOCG00000009563.1|UniProtKB=W5MTH7 W5MTH7 PTHR10472:SF1 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 2 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;deacylase activity#GO:0160215;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787 RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 esterase#PC00097;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014796.1|UniProtKB=W5NC59 W5NC59 PTHR10966:SF0 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 LEPOC|Ensembl=ENSLOCG00000009532.1|UniProtKB=W5MTE1 W5MTE1 PTHR22750:SF3 G-PROTEIN COUPLED RECEPTOR ADRENOCORTICOTROPIC HORMONE RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000001796.1|UniProtKB=W5M123 W5M123 PTHR11849:SF318 ETS SI:CH211-265G22.4 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000000772.1|UniProtKB=W5LXJ5 W5LXJ5 PTHR12713:SF38 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;cellular component organization#GO:0016043;homeostatic process#GO:0042592;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;cellular homeostasis#GO:0019725;vesicle organization#GO:0016050;synaptic vesicle maturation#GO:0016188;proton transmembrane transport#GO:1902600;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;developmental maturation#GO:0021700;vesicle-mediated transport#GO:0016192 cell junction#GO:0030054;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;ATPase dependent transmembrane transport complex#GO:0098533;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;exocytic vesicle#GO:0070382;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;cation-transporting ATPase complex#GO:0090533 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000001152.1|UniProtKB=W5LYW4 W5LYW4 PTHR13052:SF3 NFRKB-RELATED NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN binding#GO:0005488;enzyme binding#GO:0019899;protease binding#GO:0002020;protein binding#GO:0005515 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000000712.1|UniProtKB=W5LXD8 W5LXD8 PTHR12901:SF14 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG, MITOCHONDRIAL intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000012571.1|UniProtKB=W5N4B6 W5N4B6 PTHR12630:SF22 N-LINKED OLIGOSACCHARIDE PROCESSING GLUCOSIDASE 2 SUBUNIT BETA protein metabolic process#GO:0019538;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;liver development#GO:0001889;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative biosynthetic process#GO:1901137;animal organ development#GO:0048513;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;metabolic process#GO:0008152;developmental process#GO:0032502;glycoprotein metabolic process#GO:0009100;multicellular organismal process#GO:0032501;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000012415.1|UniProtKB=W5N3S7 W5N3S7 PTHR13857:SF4 MRNA EDITING ENZYME C-U-EDITING ENZYME APOBEC-2 RNA binding#GO:0003723;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;base conversion or substitution editing#GO:0016553;metabolic process#GO:0008152;RNA modification#GO:0009451;nucleobase-containing compound metabolic process#GO:0006139;cytidine to uridine editing#GO:0016554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000009744.1|UniProtKB=W5MU45 W5MU45 PTHR31777:SF0 TRANSMEMBRANE PROTEIN 169 TRANSMEMBRANE PROTEIN 169 LEPOC|Ensembl=ENSLOCG00000013006.1|UniProtKB=W5N5W1 W5N5W1 PTHR11655:SF16 60S/50S RIBOSOMAL PROTEIN L6/L9 LARGE RIBOSOMAL SUBUNIT PROTEIN UL6 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000007532.1|UniProtKB=W5ML83 W5ML83 PTHR45807:SF6 TYROSINE-PROTEIN KINASE HOPSCOTCH NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;hormone receptor binding#GO:0051427;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;non-membrane spanning protein tyrosine kinase activity#GO:0004715;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;response to peptide#GO:1901652;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;type I interferon-mediated signaling pathway#GO:0060337;response to oxygen-containing compound#GO:1901700;response to cytokine#GO:0034097;response to chemical#GO:0042221;defense response to other organism#GO:0098542;cell surface receptor signaling pathway via STAT#GO:0097696;response to biotic stimulus#GO:0009607;response to hormone#GO:0009725;response to stress#GO:0006950;signal transduction#GO:0007165;defense response to symbiont#GO:0140546;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to type II interferon#GO:0034341;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;cellular response to peptide hormone stimulus#GO:0071375;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to other organism#GO:0051707;response to peptide hormone#GO:0043434;immune response#GO:0006955;innate immune response#GO:0045087;cellular developmental process#GO:0048869;response to external stimulus#GO:0009605;defense response#GO:0006952;developmental process#GO:0032502;cell surface receptor signaling pathway via JAK-STAT#GO:0007259 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>JAK#P00846 LEPOC|Ensembl=ENSLOCG00000002263.1|UniProtKB=W5M2P4 W5M2P4 PTHR10024:SF249 SYNAPTOTAGMIN SYNAPTOTAGMIN-8 molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149 transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;regulation of exocytosis#GO:0017157;localization#GO:0051179;regulation of secretion#GO:0051046;cell communication#GO:0007154;secretion#GO:0046903;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulated exocytosis#GO:0045055;exocytosis#GO:0006887;positive regulation of vesicle fusion#GO:0031340;regulation of localization#GO:0032879;regulation of transport#GO:0051049;vesicle-mediated transport in synapse#GO:0099003;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;signaling#GO:0023052;export from cell#GO:0140352;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of cellular component organization#GO:0051128;regulation of neurotransmitter secretion#GO:0046928 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;axon#GO:0030424;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;organelle membrane#GO:0031090;plasma membrane#GO:0005886;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 LEPOC|Ensembl=ENSLOCG00000000868.1|UniProtKB=W5LXW4 W5LXW4 PTHR12371:SF4 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 2 protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000002753.1|UniProtKB=W5M4D7 W5M4D7 PTHR21541:SF3 BTB POZ DOMAIN CONTAINING 12 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4 organelle fission#GO:0048285;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;homologous recombination#GO:0035825;reproductive process#GO:0022414;cellular component organization#GO:0016043;meiosis I#GO:0007127;nucleic acid metabolic process#GO:0090304;meiotic cell cycle process#GO:1903046;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;cellular process#GO:0009987;resolution of meiotic recombination intermediates#GO:0000712 organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 LEPOC|Ensembl=ENSLOCG00000006572.1|UniProtKB=W5MHS9 W5MHS9 PTHR24393:SF146 ZINC FINGER PROTEIN ZINC FINGER PROTEIN GFI-1B DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cell differentiation#GO:0045595;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of multicellular organismal process#GO:0051239;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cell development#GO:0060284;regulation of hemopoiesis#GO:1903706;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000016446.1|UniProtKB=W5NI52 W5NI52 PTHR12547:SF174 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36L2 RNA binding#GO:0003723;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182;protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090 metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010445.1|UniProtKB=W5MWP1 W5MWP1 PTHR15710:SF261 E3 UBIQUITIN-PROTEIN LIGASE PRAJA RING-TYPE E3 UBIQUITIN TRANSFERASE regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of response to stimulus#GO:0048584;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;positive regulation of intracellular signal transduction#GO:1902533 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000006025.1|UniProtKB=W5MFW6 W5MFW6 PTHR24376:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 544-RELATED zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000016712.1|UniProtKB=W5NJ44 W5NJ44 PTHR15627:SF14 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 PROTEIN YIPF3 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000001471.1|UniProtKB=W5M048 W5M048 PTHR13817:SF68 TITIN CELL ADHESION MOLECULE DSCAM structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011125.1|UniProtKB=W5MZ59 W5MZ59 PTHR19346:SF2 SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN SOLUTE CARRIER FAMILY 35 MEMBER F4 LEPOC|Ensembl=ENSLOCG00000004083.1|UniProtKB=W5M947 W5M947 PTHR10857:SF6 COPINE COPINE-7 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 response to chemical#GO:0042221;response to stimulus#GO:0050896;response to calcium ion#GO:0051592;response to metal ion#GO:0010038;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 calcium-binding protein#PC00060 LEPOC|Ensembl=ENSLOCG00000008468.1|UniProtKB=W5MPJ6 W5MPJ6 PTHR15110:SF2 REGULATORY FACTOR X-ASSOCIATED PROTEIN REGULATORY FACTOR X-ASSOCIATED PROTEIN regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000010694.1|UniProtKB=W5MXI9 W5MXI9 PTHR11890:SF51 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR TYPE 1 cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002037.1|UniProtKB=W5M1V1 W5M1V1 PTHR12039:SF18 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE_NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 2 nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000006007.1|UniProtKB=W5MFW3 W5MFW3 PTHR46877:SF16 EPH RECEPTOR A5 EPHRIN TYPE-A RECEPTOR 10 protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of cellular process#GO:0050794;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013929.1|UniProtKB=W5N964 W5N964 PTHR10005:SF8 SKI ONCOGENE-RELATED SKI FAMILY TRANSCRIPTIONAL COREPRESSOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of BMP signaling pathway#GO:0030514;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of BMP signaling pathway#GO:0030510;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000003218.1|UniProtKB=W5M5Z6 W5M5Z6 PTHR11062:SF97 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-1 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000010099.1|UniProtKB=W5MVE7 W5MVE7 PTHR36866:SF1 CHROMOSOME 4 OPEN READING FRAME 50 GENE 1043-RELATED LEPOC|Ensembl=ENSLOCG00000003662.1|UniProtKB=W5M7I8 W5M7I8 PTHR24027:SF433 CADHERIN-23 CADHERIN-LIKE PROTEIN 26-RELATED beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell motility#GO:0048870;cell migration#GO:0016477;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 cell adhesion molecule#PC00069;cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000012778.1|UniProtKB=W5N518 W5N518 PTHR13318:SF47 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN 20 metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 LEPOC|Ensembl=ENSLOCG00000001277.1|UniProtKB=W5LZ90 W5LZ90 PTHR23049:SF81 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT POLYPEPTIDE 9 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;myosin binding#GO:0017022 developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure morphogenesis#GO:0009653;muscle cell development#GO:0055001;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin filament bundle#GO:0032432;myofibril#GO:0030016;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;stress fiber#GO:0001725;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;actomyosin#GO:0042641;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000010215.1|UniProtKB=W5MVU6 W5MVU6 PTHR48430:SF2 PARTNER OF XRN-2 PROTEIN 1 CDKN2A-INTERACTING PROTEIN N-TERMINAL-LIKE LEPOC|Ensembl=ENSLOCG00000016570.1|UniProtKB=W5NIK9 W5NIK9 PTHR34031:SF1 CENTROSOMAL PROTEIN OF 162 KDA CENTROSOMAL PROTEIN OF 162 KDA cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;ciliary plasm#GO:0097014;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;microtubule#GO:0005874;axoneme#GO:0005930;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cilium#GO:0005929;organelle#GO:0043226;nucleoplasm#GO:0005654;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000011772.1|UniProtKB=W5N1G3 W5N1G3 PTHR11860:SF111 POLYMERIC-IMMUNOGLOBULIN RECEPTOR IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000013950.1|UniProtKB=W5N989 W5N989 PTHR46688:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 LEPOC|Ensembl=ENSLOCG00000002024.1|UniProtKB=W5M1V2 W5M1V2 PTHR24055:SF584 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Parkinson disease#P00049>ERK#P01211;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Apoptosis signaling pathway#P00006>MAPK#P00269;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Endothelin signaling pathway#P00019>ERK#P00566;Ras Pathway#P04393>ERK#P04542;T cell activation#P00053>ERK#P01300;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>MEK#P00225;CCKR signaling map#P06959>MAPK1/3#P07228;Integrin signalling pathway#P00034>ERK#P00907;Interleukin signaling pathway#P00036>ERK#P00965;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MAPK#P05937;B cell activation#P00010>ERK#P00371;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;CCKR signaling map#P06959>MAPK1#P07166;VEGF signaling pathway#P00056>MEK#P01402;FGF signaling pathway#P00021>ERK1-2#P00627;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Angiogenesis#P00005>Erk#P00203;Toll receptor signaling pathway#P00054>ERK2#P01356;Gonadotropin-releasing hormone receptor pathway#P06664>ERK1/2#P06786;VEGF signaling pathway#P00056>Erk#P01407 LEPOC|Ensembl=ENSLOCG00000001883.1|UniProtKB=W5M1C2 W5M1C2 PTHR21641:SF0 TRANSLATION INITIATION FACTOR-RELATED RNA-BINDING PROTEIN EIF1AD-RELATED intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000006904.1|UniProtKB=W5MJ24 W5MJ24 PTHR14491:SF9 SOSONDOWAH, ISOFORM G ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHA ISOFORM X3 LEPOC|Ensembl=ENSLOCG00000016023.1|UniProtKB=W5NGI4 W5NGI4 PTHR11036:SF25 SEMAPHORIN SEMAPHORIN-3C signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;neural crest cell differentiation#GO:0014033;neuron differentiation#GO:0030182;mesenchymal cell differentiation#GO:0048762;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neural crest cell migration#GO:0001755;taxis#GO:0042330;response to chemical#GO:0042221;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;stem cell development#GO:0048864;chemotaxis#GO:0006935;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;cellular response to stimulus#GO:0051716;cell motility#GO:0048870;regulation of cellular process#GO:0050794;locomotion#GO:0040011;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;mesenchyme development#GO:0060485;neurogenesis#GO:0022008;axon guidance#GO:0007411;stem cell differentiation#GO:0048863;axon development#GO:0061564;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;multicellular organismal process#GO:0032501;cell migration#GO:0016477;tissue development#GO:0009888;neural crest cell development#GO:0014032;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000016424.1|UniProtKB=W5NI26 W5NI26 PTHR19328:SF54 HEDGEHOG-INTERACTING PROTEIN HHIP-LIKE PROTEIN 2 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000002321.1|UniProtKB=W5M2W6 W5M2W6 PTHR10546:SF1 SODIUM CHANNEL SUBUNIT BETA-1 AND 3 SODIUM CHANNEL REGULATORY SUBUNIT BETA-3 ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;binding#GO:0005488;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;protein binding#GO:0005515 regulation of heart contraction#GO:0008016;striated muscle contraction#GO:0006941;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;actin-mediated cell contraction#GO:0070252;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;circulatory system process#GO:0003013;monoatomic cation transport#GO:0006812;localization#GO:0051179;actin filament-based movement#GO:0030048;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;transport#GO:0006810;muscle contraction#GO:0006936;regulation of system process#GO:0044057;heart contraction#GO:0060047;system process#GO:0003008;cardiac muscle cell contraction#GO:0086003;establishment of localization#GO:0051234;heart process#GO:0003015;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;muscle system process#GO:0003012;action potential#GO:0001508;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;cardiac muscle cell action potential involved in contraction#GO:0086002;regulation of membrane potential#GO:0042391 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ion channel#PC00133;voltage-gated ion channel#PC00241 LEPOC|Ensembl=ENSLOCG00000001346.1|UniProtKB=W5LZJ3 W5LZJ3 PTHR46240:SF1 SER/THR PROTEIN KINASE ULK4 INACTIVE SERINE_THREONINE-PROTEIN KINASE ULK4 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000009533.1|UniProtKB=W5MTE6 W5MTE6 GHRHR PTHR45620:SF14 PDF RECEPTOR-LIKE PROTEIN-RELATED GROWTH HORMONE-RELEASING HORMONE RECEPTOR molecular transducer activity#GO:0060089;protein binding#GO:0005515;growth factor binding#GO:0019838;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000009784.1|UniProtKB=W5MU93 W5MU93 PTHR45688:SF6 FAMILY NOT NAMED 5-PHOSPHOHYDROXY-L-LYSINE PHOSPHO-LYASE LEPOC|Ensembl=ENSLOCG00000001911.1|UniProtKB=W5M1E7 W5M1E7 PTHR15416:SF5 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI CAMP-DEPENDENT PROTEIN KINASE INHIBITOR GAMMA molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;enzyme inhibitor activity#GO:0004857 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 kinase inhibitor#PC00139;kinase modulator#PC00140 LEPOC|Ensembl=ENSLOCG00000013031.1|UniProtKB=W5N5Z4 W5N5Z4 PTHR21838:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 137 COILED-COIL DOMAIN-CONTAINING PROTEIN 137 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000008256.1|UniProtKB=W5MNR7 W5MNR7 GUCY1A1 PTHR45655:SF2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1 guanylate cyclase activity#GO:0004383;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;response to abiotic stimulus#GO:0009628;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cyclic nucleotide biosynthetic process#GO:0009190;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;response to oxygen levels#GO:0070482;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407 cytosol#GO:0005829;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cyclase#PC00079;guanylate cyclase#PC00114 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581;Gonadotropin-releasing hormone receptor pathway#P06664>GC#P06726 LEPOC|Ensembl=ENSLOCG00000012623.1|UniProtKB=W5N4I1 W5N4I1 PTHR12873:SF7 T7-LIKE MITOCHONDRIAL DNA HELICASE TWINKLE MTDNA HELICASE single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;mitochondrial DNA metabolic process#GO:0032042;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA helicase#PC00011 LEPOC|Ensembl=ENSLOCG00000009033.1|UniProtKB=W5MRK7 W5MRK7 PTHR12592:SF0 ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 metabolic process#GO:0008152;cellular process#GO:0009987 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000006545.1|UniProtKB=W5MHP9 W5MHP9 PTHR10217:SF380 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL VOLTAGE-GATED DELAYED RECTIFIER POTASSIUM CHANNEL KCNH8 voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;potassium ion transport#GO:0006813;biological regulation#GO:0065007;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of membrane potential#GO:0042391;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009302.1|UniProtKB=W5MSJ0 W5MSJ0 PTHR12002:SF15 CLAUDIN CLAUDIN cell junction organization#GO:0034330;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000016250.1|UniProtKB=W5NHE8 W5NHE8 PTHR32170:SF5 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134;enzyme activator activity#GO:0008047 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369 LEPOC|Ensembl=ENSLOCG00000010225.1|UniProtKB=W5MVW6 W5MVW6 PTHR10894:SF1 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 58 RNA binding#GO:0003723;snoRNA binding#GO:0030515;binding#GO:0005488;nucleic acid binding#GO:0003676 small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015088.1|UniProtKB=W5ND60 W5ND60 PTHR46088:SF1 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000009462.1|UniProtKB=W5MT43 W5MT43 PTHR28635:SF1 TRANSMEMBRANE INNER EAR EXPRESSED PROTEIN TRANSMEMBRANE INNER EAR EXPRESSED PROTEIN system process#GO:0003008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;developmental process#GO:0032502;sensory organ development#GO:0007423;embryo development#GO:0009790;multicellular organismal process#GO:0032501;inner ear development#GO:0048839;inner ear morphogenesis#GO:0042472;ear development#GO:0043583;anatomical structure development#GO:0048856;nervous system process#GO:0050877;embryonic organ development#GO:0048568;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;animal gross anatomical part developmental process#GO:0160108;sensory organ morphogenesis#GO:0090596;animal organ morphogenesis#GO:0009887;sensory perception of sound#GO:0007605;anatomical structure morphogenesis#GO:0009653 LEPOC|Ensembl=ENSLOCG00000012536.1|UniProtKB=W5N487 W5N487 PTHR24217:SF9 PUTATIVE-RELATED SYNAPTOPODIN-2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle cell development#GO:0055001;regulation of supramolecular fiber organization#GO:1902903;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;regulation of cytoskeleton organization#GO:0051493;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cellular developmental process#GO:0048869;positive regulation of actin filament bundle assembly#GO:0032233;positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;striated muscle cell development#GO:0055002;positive regulation of organelle organization#GO:0010638;regulation of actin filament bundle assembly#GO:0032231;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of Rho protein signal transduction#GO:0035023;actomyosin structure organization#GO:0031032;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;Z disc#GO:0030018;actomyosin#GO:0042641;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cell junction#GO:0030054;I band#GO:0031674;stress fiber#GO:0001725;cytoskeleton#GO:0005856;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000016835.1|UniProtKB=W5NJJ9 W5NJJ9 PTHR11037:SF16 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 1 HOMOLOG binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015671.1|UniProtKB=W5NF83 W5NF83 PTHR31735:SF3 VACUOLAR MEMBRANE PROTEIN YPL162C TRANSMEMBRANE PROTEIN 110-RELATED cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000013887.1|UniProtKB=W5N925 W5N925 PTHR18929:SF263 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;response to stimulus#GO:0050896;protein maturation#GO:0051604;gene expression#GO:0010467;cellular response to stress#GO:0033554;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000008398.1|UniProtKB=W5MPA6 W5MPA6 PTHR24347:SF401 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell growth#GO:0016049;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;axon extension#GO:0048675;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;developmental growth#GO:0048589;neurogenesis#GO:0022008;axon development#GO:0061564;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;anatomical structure development#GO:0048856;system development#GO:0048731;developmental cell growth#GO:0048588 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017729.1|UniProtKB=W5NMH4 W5NMH4 PTHR24234:SF7 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G PROTEIN-COUPLED RECEPTOR 132-RELATED biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cell cycle G1/S phase transition#GO:0044843;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;mitotic cell cycle process#GO:1903047;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle process#GO:0010948;G1/S transition of mitotic cell cycle#GO:0000082;negative regulation of cellular process#GO:0048523;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic cell cycle phase transition#GO:0044772 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017037.1|UniProtKB=W5NKA1 W5NKA1 PTHR19282:SF163 TETRASPANIN CD9 ANTIGEN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009928.1|UniProtKB=W5MUS9 W5MUS9 PTHR12329:SF2 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 5 protein-folding chaperone binding#GO:0051087;binding#GO:0005488;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of protein stability#GO:0031647;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;protein stabilization#GO:0050821;regulation of protein modification process#GO:0031399;regulation of protein ubiquitination#GO:0031396;negative regulation of cellular process#GO:0048523;negative regulation of protein metabolic process#GO:0051248;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;regulation of post-translational protein modification#GO:1901873;negative regulation of protein ubiquitination#GO:0031397 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000014423.1|UniProtKB=W5NAU3 W5NAU3 PTHR45690:SF19 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 3 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000016704.1|UniProtKB=W5NJ38 W5NJ38 PTHR22727:SF3 PROTEIN CBG13728 ENDOSOME_LYSOSOME-ASSOCIATED APOPTOSIS AND AUTOPHAGY REGULATOR FAMILY MEMBER 2 positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of BMP signaling pathway#GO:0030513;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of BMP signaling pathway#GO:0030510;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000008054.1|UniProtKB=W5MN30 W5MN30 PTHR12349:SF5 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 PALMITOYLTRANSFERASE ZDHHC5-A-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to external stimulus#GO:0032101;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;positive regulation of immune system process#GO:0002684;positive regulation of pattern recognition receptor signaling pathway#GO:0062208;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;positive regulation of response to external stimulus#GO:0032103;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134 LEPOC|Ensembl=ENSLOCG00000004413.1|UniProtKB=W5MA79 W5MA79 PTHR24040:SF7 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN FIBRILLIN 2B extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000012592.1|UniProtKB=W5N4E1 W5N4E1 PTHR21584:SF1 DIFFERENTIAL DISPLAY AND ACTIVATED BY P53 DDA3 /G2 S PHASE EXPRESSED 1 PROLINE_SERINE-RICH COILED-COIL PROTEIN 1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;chromosome localization#GO:0050000;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic metaphase chromosome alignment#GO:0007080;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;organelle localization#GO:0051640;nuclear division#GO:0000280;organelle fission#GO:0048285;localization#GO:0051179 supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;spindle#GO:0005819;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spindle pole#GO:0000922;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009782.1|UniProtKB=W5MU94 W5MU94 PTHR24418:SF87 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 LEPOC|Ensembl=ENSLOCG00000012643.1|UniProtKB=W5N4K3 W5N4K3 PTHR35346:SF1 BEN DOMAIN-CONTAINING PROTEIN 6 BEN DOMAIN-CONTAINING PROTEIN 6 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of developmental process#GO:0050793;negative regulation of signaling#GO:0023057;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of neuron differentiation#GO:0045664;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;negative regulation of Notch signaling pathway#GO:0045746;positive regulation of developmental process#GO:0051094 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000001370.1|UniProtKB=W5LZL2 W5LZL2 PTHR12920:SF2 RYBP AND YAF2-RELATED YY1-ASSOCIATED FACTOR 2 DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000010900.1|UniProtKB=W5MYA5 W5MYA5 PTHR13948:SF37 RNA-BINDING PROTEIN RNA BINDING MOTIF PROTEIN 6 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000013621.1|UniProtKB=W5N836 W5N836 PTHR48051:SF14 FAMILY NOT NAMED LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 2 ISOFORM X1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000001660.1|UniProtKB=W5M0K6 W5M0K6 PTHR10686:SF42 FOLATE TRANSPORTER SOLUTE CARRIER FAMILY 19 MEMBER 2 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000004023.1|UniProtKB=W5M8U6 W5M8U6 PTHR23333:SF4 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 11 protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000007411.1|UniProtKB=W5MKU0 W5MKU0 PTHR10015:SF274 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000003790.1|UniProtKB=W5M830 W5M830 PTHR10534:SF2 PYRIDOXAL KINASE PYRIDOXAL KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524;small molecule biosynthetic process#GO:0044283;organophosphate biosynthetic process#GO:0090407 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 kinase#PC00137 Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine kinase#P03122;Vitamin B6 metabolism#P02787>Pyridoxal kinase#P03244;Pyridoxal phosphate salvage pathway#P02770>Pyridoxal kinase#P03121 LEPOC|Ensembl=ENSLOCG00000017748.1|UniProtKB=W5NMJ3 W5NMJ3 PTHR11829:SF156 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN E3 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000017984.1|UniProtKB=W5NN76 W5NN76 PTHR16155:SF18 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000004608.1|UniProtKB=W5MAW9 W5MAW9 PTHR24178:SF21 MOLTING PROTEIN MLT-4 ANKYRIN REPEAT AND SOCS BOX PROTEIN 3 macromolecule localization#GO:0033036;protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to cilium#GO:0061512 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000004612.1|UniProtKB=W5MAZ0 W5MAZ0 PTHR24027:SF300 CADHERIN-23 CADHERIN-15 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cell migration#GO:0016477;cell motility#GO:0048870;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 LEPOC|Ensembl=ENSLOCG00000017378.1|UniProtKB=W5NLH4 W5NLH4 PTHR24070:SF194 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2B hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell migration#GO:0030334;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;intracellular signaling cassette#GO:0141124;regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 LEPOC|Ensembl=ENSLOCG00000015371.1|UniProtKB=W5NE60 W5NE60 PTHR11453:SF137 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;bicarbonate transmembrane transporter activity#GO:0015106;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000012745.1|UniProtKB=W5N4X0 W5N4X0 PTHR24118:SF104 POTE ANKYRIN DOMAIN ANKYRIN REPEAT AND SOCS BOX PROTEIN 7 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;Cul5-RING ubiquitin ligase complex#GO:0031466;protein-containing complex#GO:0032991 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000009692.1|UniProtKB=W5MTX7 W5MTX7 PTHR12431:SF15 SORTING NEXIN 17 AND 27 SORTING NEXIN-31 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;localization within membrane#GO:0051668;establishment of localization#GO:0051234;cellular localization#GO:0051641;macromolecule metabolic process#GO:0043170;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000009815.1|UniProtKB=W5MUE8 W5MUE8 PTHR25465:SF5 B-BOX DOMAIN CONTAINING BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 30 ISOFORM X1-RELATED ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000002421.1|UniProtKB=W5M384 W5M384 PTHR11588:SF429 TUBULIN TUBULIN BETA 8B-RELATED purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 tubulin#PC00228;cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 LEPOC|Ensembl=ENSLOCG00000013857.1|UniProtKB=W5N8Y3 W5N8Y3 PTHR11977:SF127 VILLIN MACROPHAGE-CAPPING PROTEIN lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of protein-containing complex disassembly#GO:0043244;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;nervous system development#GO:0007399;regulation of anatomical structure size#GO:0090066;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;central nervous system development#GO:0007417;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;animal gross anatomical part developmental process#GO:0160108;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;actin filament organization#GO:0007015;regulation of protein depolymerization#GO:1901879;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of actin filament depolymerization#GO:0030834;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;actin filament-based process#GO:0030029;negative regulation of cytoskeleton organization#GO:0051494;anatomical structure development#GO:0048856;negative regulation of protein-containing complex disassembly#GO:0043242;system development#GO:0048731;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 LEPOC|Ensembl=ENSLOCG00000010192.1|UniProtKB=W5MVS3 W5MVS3 PTHR11860:SF87 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CD300 MOLECULE LIKE FAMILY MEMBER G-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin receptor superfamily#PC00124;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002222.1|UniProtKB=W5M2H8 W5M2H8 PTHR21446:SF12 DUF3504 DOMAIN-CONTAINING PROTEIN POTASSIUM CHANNEL TETRAMERIZATION DOMAIN CONTAINING 1 LEPOC|Ensembl=ENSLOCG00000014567.1|UniProtKB=W5NBC8 W5NBC8 PTHR24023:SF1071 COLLAGEN ALPHA COLLAGEN ALPHA-1(VII) CHAIN extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198 basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000010588.1|UniProtKB=W5MX69 W5MX69 PTHR11848:SF34 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-3 PROPROTEIN signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cellular response to transforming growth factor beta stimulus#GO:0071560;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;circulatory system development#GO:0072359;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to transforming growth factor beta#GO:0071559;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor signaling pathway#GO:0007179;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;animal organ development#GO:0048513;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000009487.1|UniProtKB=W5MT76 W5MT76 PTHR46608:SF3 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;small molecule binding#GO:0036094;binding#GO:0005488;phospholipid binding#GO:0005543;anion binding#GO:0043168;ion binding#GO:0043167 apoptotic cell clearance#GO:0043277;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;endocytosis#GO:0006897;phagocytosis#GO:0006909;transport#GO:0006810 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000007525.1|UniProtKB=W5ML69 W5ML69 PTHR12876:SF26 N4BP1-RELATED NEDD4-BINDING PROTEIN 1 RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;RNA destabilization#GO:0050779;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of protein ubiquitination#GO:0031397;regulation of biological quality#GO:0065008;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of protein ubiquitination#GO:0031396;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of protein modification process#GO:0031399;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of mRNA catabolic process#GO:0061014;negative regulation of proteasomal protein catabolic process#GO:1901799;positive regulation of RNA metabolic process#GO:0051254;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000002769.1|UniProtKB=W5M4F6 W5M4F6 PTHR24404:SF53 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 148 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000018191.1|UniProtKB=W5NNT3 W5NNT3 PTHR35972:SF1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 LEPOC|Ensembl=ENSLOCG00000011313.1|UniProtKB=W5MZU2 W5MZU2 PTHR12268:SF13 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000009745.1|UniProtKB=W5MU46 W5MU46 PTHR28682:SF2 INHIBITORY SYNAPTIC FACTOR 2A-RELATED PROTEIN INSYN2B LEPOC|Ensembl=ENSLOCG00000005329.1|UniProtKB=W5MDG3 W5MDG3 PTHR12411:SF965 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L.1 ISOFORM X1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008717.1|UniProtKB=W5MQF2 W5MQF2 PTHR22802:SF475 C-TYPE LECTIN SUPERFAMILY MEMBER CD302 ANTIGEN carbohydrate binding#GO:0030246;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488 immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000008954.1|UniProtKB=W5MR97 W5MR97 PTHR10529:SF345 AP COMPLEX SUBUNIT MU STONIN-2 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 biological regulation#GO:0065007;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of localization#GO:0032879;receptor-mediated endocytosis#GO:0006898;regulation of transport#GO:0051049;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;Golgi vesicle transport#GO:0048193;vacuolar transport#GO:0007034;regulation of endocytosis#GO:0030100;intracellular transport#GO:0046907;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of cellular component organization#GO:0051128;clathrin-dependent endocytosis#GO:0072583;regulation of biological process#GO:0050789;synaptic vesicle endocytosis#GO:0048488;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;localization#GO:0051179 organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;synapse#GO:0045202;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;coated membrane#GO:0048475;endocytic vesicle#GO:0030139;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell junction#GO:0030054;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin vesicle coat#GO:0030125;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;synaptic vesicle#GO:0008021;plasma membrane protein complex#GO:0098797;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;vesicle membrane#GO:0012506;cytosol#GO:0005829;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000003170.1|UniProtKB=W5M5U1 W5M5U1 CIAPIN1 PTHR13273:SF14 ANAMORSIN ANAMORSIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000016763.1|UniProtKB=W5NJB5 W5NJB5 PTHR12277:SF61 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN LYSOPHOSPHATIDYLSERINE LIPASE ABHD12 hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;lipase activity#GO:0016298 catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;glycerolipid catabolic process#GO:0046503;glycerophospholipid metabolic process#GO:0006650;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;neutral lipid metabolic process#GO:0006638;glycerophospholipid catabolic process#GO:0046475;acylglycerol catabolic process#GO:0046464;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000007070.1|UniProtKB=W5MJK0 W5MJK0 PTHR23428:SF344 HISTONE H2B HISTONE H2B-RELATED biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to other organism#GO:0051707;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;humoral immune response#GO:0006959;response to external stimulus#GO:0009605;defense response#GO:0006952;antibacterial humoral response#GO:0019731;innate immune response#GO:0045087 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000008790.1|UniProtKB=W5MQP2 W5MQP2 PTHR15736:SF4 PROTEIN FAM131B-RELATED PROTEIN FAM131A LEPOC|Ensembl=ENSLOCG00000007859.1|UniProtKB=W5MME2 W5MME2 PTHR21139:SF2 TRIOSEPHOSPHATE ISOMERASE TRIOSEPHOSPHATE ISOMERASE intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;ADP catabolic process#GO:0046032;carbohydrate biosynthetic process#GO:0016051;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;pyruvate metabolic process#GO:0006090;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;aldehyde metabolic process#GO:0006081;glyceraldehyde-3-phosphate metabolic process#GO:0019682;oxoacid metabolic process#GO:0043436;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;purine nucleotide catabolic process#GO:0006195;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;purine ribonucleotide catabolic process#GO:0009154;hexose biosynthetic process#GO:0019319;nucleoside diphosphate catabolic process#GO:0009134 metabolite interconversion enzyme#PC00262;isomerase#PC00135 Glycolysis#P00024>Triosephosphate isomerase#P00673 LEPOC|Ensembl=ENSLOCG00000001505.1|UniProtKB=W5M033 W5M033 PTHR43020:SF2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1 MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1 small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098 cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA modification#GO:1900864;mitochondrial gene expression#GO:0140053;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000005395.1|UniProtKB=W5MDP5 W5MDP5 PTHR11723:SF16 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-3 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nervous system development#GO:0007399;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Id3#P06711 LEPOC|Ensembl=ENSLOCG00000012323.1|UniProtKB=W5N3F8 W5N3F8 PTHR19432:SF34 SUGAR TRANSPORTER MEMBRANE-ASSOCIATED TRANSPORTER PROTEIN proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324 secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152;pigmentation#GO:0043473;pigment biosynthetic process#GO:0046148;melanin biosynthetic process#GO:0042438;secondary metabolic process#GO:0019748;pigment metabolic process#GO:0042440;phenol-containing compound biosynthetic process#GO:0046189;cellular process#GO:0009987;developmental pigmentation#GO:0048066;phenol-containing compound metabolic process#GO:0018958;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic vesicle membrane#GO:0030659;melanosome#GO:0042470;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000008809.1|UniProtKB=W5MQR0 W5MQR0 PTHR45532:SF1 WD REPEAT-CONTAINING PROTEIN 97 WD REPEAT-CONTAINING PROTEIN 97 LEPOC|Ensembl=ENSLOCG00000017155.1|UniProtKB=W5NKP1 W5NKP1 PTHR45738:SF5 POLYPHOSPHOINOSITIDE PHOSPHATASE POLYPHOSPHOINOSITIDE PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018 phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;dephosphorylation#GO:0016311;lipid modification#GO:0030258;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121;phosphatase#PC00181 LEPOC|Ensembl=ENSLOCG00000017020.1|UniProtKB=W5NK80 W5NK80 PTHR11348:SF7 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 2 glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of developmental process#GO:0050793;cell adhesion#GO:0007155;cell communication#GO:0007154;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;biological regulation#GO:0065007;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000016802.1|UniProtKB=W5NJF9 W5NJF9 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000000979.1|UniProtKB=W5LY95 W5LY95 PTHR10269:SF16 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-4A PRECURSOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;system development#GO:0048731;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012314.1|UniProtKB=W5N3E1 W5N3E1 PTHR28572:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 103 DYNEIN AXONEMAL ASSEMBLY FACTOR 19 plasma membrane bounded cell projection assembly#GO:0120031;specification of symmetry#GO:0009799;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regionalization#GO:0003002;plasma membrane bounded cell projection organization#GO:0120036;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;axoneme assembly#GO:0035082;organelle assembly#GO:0070925;axonemal dynein complex assembly#GO:0070286;microtubule bundle formation#GO:0001578;pattern specification process#GO:0007389;determination of left/right symmetry#GO:0007368;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;left/right pattern formation#GO:0060972;cellular component assembly#GO:0022607;determination of bilateral symmetry#GO:0009855;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium organization#GO:0044782;inner dynein arm assembly#GO:0036159;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein-containing complex assembly#GO:0065003 LEPOC|Ensembl=ENSLOCG00000000552.1|UniProtKB=W5LWV2 W5LWV2 PTHR14454:SF6 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;biological regulation#GO:0065007;epidermal growth factor receptor signaling pathway#GO:0007173;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794 LEPOC|Ensembl=ENSLOCG00000002489.1|UniProtKB=W5M3G3 W5M3G3 PTHR26450:SF391 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000005197.1|UniProtKB=W5MD14 W5MD14 PTHR12587:SF15 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cell junction#GO:0030054;presynaptic active zone#GO:0048786;synapse#GO:0045202;cellular anatomical structure#GO:0110165;presynapse#GO:0098793 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007870.1|UniProtKB=W5MME5 W5MME5 PTHR10872:SF1 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 3 enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;receptor tyrosine kinase binding#GO:0030971;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090 cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of response to cytokine stimulus#GO:0060759;response to chemokine#GO:1990868;biological regulation#GO:0065007;hemopoiesis#GO:0030097;negative regulation of response to stimulus#GO:0048585;response to cytokine#GO:0034097;response to chemical#GO:0042221;G protein-coupled receptor signaling pathway#GO:0007186;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;intracellular signal transduction#GO:0035556;anatomical structure development#GO:0048856;cell communication#GO:0007154;chemokine-mediated signaling pathway#GO:0070098;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cell development#GO:0048468;cellular response to chemokine#GO:1990869;signaling#GO:0023052;negative regulation of response to cytokine stimulus#GO:0060761;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011906.1|UniProtKB=W5N1Y4 W5N1Y4 PTHR19282:SF511 TETRASPANIN TETRASPANIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004531.1|UniProtKB=W5MAL0 W5MAL0 PTHR22978:SF6 B-CELL TRANSLOCATION GENE PROTEIN BTG3 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000009311.1|UniProtKB=W5MSJ7 W5MSJ7 PTHR15746:SF14 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 5 transport#GO:0006810;regulated exocytosis#GO:0045055;secretion by cell#GO:0032940;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192 endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;recycling endosome#GO:0055037;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;secretory granule#GO:0030141;endosome#GO:0005768;intracellular organelle#GO:0043229 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000007862.1|UniProtKB=W5MMD5 W5MMD5 PTHR21255:SF20 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 3 protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000000197.1|UniProtKB=W5LVR3 W5LVR3 PTHR12259:SF2 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC3 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006236.1|UniProtKB=W5MGM3 W5MGM3 PTHR16950:SF16 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER ZIP13 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000008891.1|UniProtKB=W5MR11 W5MR11 PTHR13323:SF4 LATE ENDOSOMAL/LYSOSOMAL MP1 INTERACTING PROTEIN RAGULATOR COMPLEX PROTEIN LAMTOR2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of TORC1 signaling#GO:1904263;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051 membrane protein complex#GO:0098796;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;vacuole#GO:0005773;cytoplasm#GO:0005737;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000016168.1|UniProtKB=W5NH13 W5NH13 PTHR23115:SF222 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 1-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000008847.1|UniProtKB=W5MQW3 W5MQW3 PTHR15948:SF8 G-PROTEIN COUPLED RECEPTOR 89-RELATED GOLGI PH REGULATOR A-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic anion channel activity#GO:0008308;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000004734.1|UniProtKB=W5MBB4 W5MBB4 PTHR46282:SF4 LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN cell differentiation#GO:0030154;cellular developmental process#GO:0048869;pigmentation#GO:0043473;developmental process#GO:0032502;melanocyte differentiation#GO:0030318;developmental pigmentation#GO:0048066;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000009987.1|UniProtKB=W5MV04 W5MV04 PTHR11158:SF23 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING PROTEIN 3A molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013 phospholipid transport#GO:0015914;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000002010.1|UniProtKB=W5M1T5 W5M1T5 PTHR15696:SF5 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG7 DNA binding#GO:0003677;RNA binding#GO:0003723;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000010463.1|UniProtKB=W5MWR3 W5MWR3 PTHR23227:SF87 BUCENTAUR RELATED PROTEIN CFDP2 LEPOC|Ensembl=ENSLOCG00000001124.1|UniProtKB=W5LYR1 W5LYR1 AK2 PTHR23359:SF234 NUCLEOTIDE KINASE ADENYLATE KINASE 2, MITOCHONDRIAL phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleoside phosphate biosynthetic process#GO:1901293;ADP metabolic process#GO:0046031;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;organophosphate biosynthetic process#GO:0090407 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase#PC00137;nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 LEPOC|Ensembl=ENSLOCG00000005523.1|UniProtKB=W5ME60 W5ME60 PTHR22874:SF1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 catabolic process#GO:0009056;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000014346.1|UniProtKB=W5NAK6 W5NAK6 PTHR14207:SF8 STEROL ISOMERASE 3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE catalytic activity#GO:0003824;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 isomerase#PC00135 LEPOC|Ensembl=ENSLOCG00000007853.1|UniProtKB=W5MMD2 W5MMD2 PTHR24356:SF150 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE_THREONINE-PROTEIN KINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 brain development#GO:0007420;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;head development#GO:0060322;nervous system development#GO:0007399;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;developmental process#GO:0032502;central nervous system development#GO:0007417;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;intracellular signal transduction#GO:0035556;animal gross anatomical part developmental process#GO:0160108 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell body#GO:0044297;microtubule cytoskeleton#GO:0015630 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000000913.1|UniProtKB=W5LY26 W5LY26 PTHR11521:SF20 TROPONIN T TROPONIN T2D, CARDIAC-RELATED binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cardiac muscle contraction#GO:0060048;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;circulatory system process#GO:0003013;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;striated muscle contraction#GO:0006941;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle contraction#GO:0006936;developmental process#GO:0032502;heart contraction#GO:0060047;system process#GO:0003008;cellular developmental process#GO:0048869;blood circulation#GO:0008015;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;heart process#GO:0003015;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cytoskeleton#GO:0005856;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000008670.1|UniProtKB=W5MQC6 W5MQC6 PTHR24025:SF18 DESMOGLEIN FAMILY MEMBER CADHERIN-23 small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000016230.1|UniProtKB=W5NHA3 W5NHA3 PTHR10126:SF69 TATA-BOX BINDING PROTEIN TATA BOX-BINDING PROTEIN-LIKE 1 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription initiation#GO:0006352;gene expression#GO:0010467;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 general transcription factor#PC00259;RNA metabolism protein#PC00031 Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;General transcription by RNA polymerase I#P00022>TBP#P00657;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription regulation#P00023>TBP#P00670 LEPOC|Ensembl=ENSLOCG00000014998.1|UniProtKB=W5NCX2 W5NCX2 PTHR16266:SF25 WD REPEAT DOMAIN 9 BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 3 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000017549.1|UniProtKB=W5NLZ5 W5NLZ5 PTHR10489:SF951 CELL ADHESION MOLECULE RELAXIN-3 RECEPTOR 2 immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;cytokine binding#GO:0019955;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;protein binding#GO:0005515;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;cell migration#GO:0016477;response to chemical#GO:0042221;taxis#GO:0042330;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;cell communication#GO:0007154;regulation of biological quality#GO:0065008;intracellular signal transduction#GO:0035556;cell chemotaxis#GO:0060326;cellular response to chemical stimulus#GO:0070887;immune system process#GO:0002376;positive regulation of cytosolic calcium ion concentration#GO:0007204;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;cell motility#GO:0048870;response to stimulus#GO:0050896;locomotion#GO:0040011;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004681.1|UniProtKB=W5MB42 W5MB42 PTHR28645:SF1 TRANSMEMBRANE PROTEIN 119 TRANSMEMBRANE PROTEIN 119 regulation of cellular process#GO:0050794;regulation of multicellular organismal process#GO:0051239;regulation of bone mineralization#GO:0030500;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;positive regulation of cell population proliferation#GO:0008284;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of cell population proliferation#GO:0042127;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000002784.1|UniProtKB=W5M4G7 W5M4G7 PTHR13994:SF46 NUDIX HYDROLASE RELATED NUDIX HYDROLASE 6 heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 hydrolase#PC00121;nucleotide phosphatase#PC00173 LEPOC|Ensembl=ENSLOCG00000010314.1|UniProtKB=W5MW81 W5MW81 PTHR12607:SF11 ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY ADENOMATOUS POLYPOSIS COLI PROTEIN beta-catenin binding#GO:0008013;protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 negative regulation of cytoskeleton organization#GO:0051494;anatomical structure development#GO:0048856;negative regulation of protein-containing complex disassembly#GO:0043242;system development#GO:0048731;regulation of microtubule-based process#GO:0032886;pattern specification process#GO:0007389;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;cellular developmental process#GO:0048869;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;cell migration#GO:0016477;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of protein depolymerization#GO:1901880;cell fate commitment#GO:0045165;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;regulation of Wnt signaling pathway#GO:0030111;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cell fate specification#GO:0001708;negative regulation of signal transduction#GO:0009968;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of protein-containing complex disassembly#GO:0043244;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;cytoplasmic microtubule#GO:0005881;plasma membrane protein complex#GO:0098797;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;cell periphery#GO:0071944;extrinsic component of membrane#GO:0019898;membraneless organelle#GO:0043228;extrinsic component of plasma membrane#GO:0019897;polymeric cytoskeletal fiber#GO:0099513;intracellular protein-containing complex#GO:0140535;cytoskeleton#GO:0005856 Wnt signaling pathway#P00057>APC#P01468;Angiogenesis#P00005>APC#P00195 LEPOC|Ensembl=ENSLOCG00000005786.1|UniProtKB=W5MF35 W5MF35 PTHR11134:SF10 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 anterograde axonal transport#GO:0008089;vacuole organization#GO:0007033;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;pigmentation#GO:0043473;organelle localization#GO:0051640;axonal transport#GO:0098930;microtubule-based movement#GO:0007018;vesicle cytoskeletal trafficking#GO:0099518;anterograde synaptic vesicle transport#GO:0048490;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;lytic vacuole organization#GO:0080171;vacuolar transport#GO:0007034;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle localization#GO:0051648;axo-dendritic transport#GO:0008088;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;establishment of organelle localization#GO:0051656;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;melanosome organization#GO:0032438;cellular pigmentation#GO:0033059;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;lysosome organization#GO:0007040;establishment of localization in cell#GO:0051649;synaptic vesicle transport#GO:0048489;organelle organization#GO:0006996 AP-type membrane coat adaptor complex#GO:0030119;intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane protein complex#GO:0098796;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000012765.1|UniProtKB=W5N4Z7 W5N4Z7 PTHR23289:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HEME A SYNTHASE COX15 chaperone#PC00072 Vitamin D metabolism and pathway#P04396>FDX#P04607 LEPOC|Ensembl=ENSLOCG00000016517.1|UniProtKB=W5NIE3 W5NIE3 PTHR34832:SF1 CENTROMERE PROTEIN W CENTROMERE PROTEIN W kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;kinetochore organization#GO:0051383;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000014374.1|UniProtKB=W5NAP3 W5NAP3 PTHR11388:SF86 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 3A1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000012574.1|UniProtKB=W5N4D7 W5N4D7 PTHR45673:SF3 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein binding#GO:0005515;binding#GO:0005488 intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;calcineurin-NFAT signaling cascade#GO:0033173;calcineurin-mediated signaling#GO:0097720 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000014322.1|UniProtKB=W5NAI4 W5NAI4 PTHR46006:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3 regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of Rho protein signal transduction#GO:0035023;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000011066.1|UniProtKB=W5MYX8 W5MYX8 PTHR19433:SF111 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 4 response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external stimulus#GO:0009605;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896 defense/immunity protein#PC00090;immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000013623.1|UniProtKB=W5N857 W5N857 PTHR22625:SF36 PLEXIN PLEXIN-B1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;regulation of axonogenesis#GO:0050770;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of cell differentiation#GO:0045597;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;positive regulation of nervous system development#GO:0051962;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;synapse assembly#GO:0007416;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;regulation of multicellular organismal development#GO:2000026;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;positive regulation of axonogenesis#GO:0050772;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;negative regulation of cell adhesion#GO:0007162;regulation of cell adhesion#GO:0030155;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of developmental process#GO:0051094;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of cell differentiation#GO:0045595;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Axon guidance mediated by semaphorins#P00007>plexinB1#P00328 LEPOC|Ensembl=ENSLOCG00000006768.1|UniProtKB=W5MIH0 W5MIH0 PTHR13869:SF14 MYELIN P0 RELATED SODIUM CHANNEL REGULATORY SUBUNIT BETA-4 binding#GO:0005488;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;transmembrane transporter binding#GO:0044325;protein binding#GO:0005515;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 circulatory system process#GO:0003013;actin filament-based process#GO:0030029;cardiac muscle contraction#GO:0060048;regulation of biological quality#GO:0065008;heart process#GO:0003015;muscle system process#GO:0003012;action potential#GO:0001508;regulation of biological process#GO:0050789;actin-mediated cell contraction#GO:0070252;regulation of heart contraction#GO:0008016;striated muscle contraction#GO:0006941;membrane depolarization#GO:0051899;regulation of system process#GO:0044057;muscle contraction#GO:0006936;cardiac muscle cell contraction#GO:0086003;regulation of membrane potential#GO:0042391;system process#GO:0003008;heart contraction#GO:0060047;actin filament-based movement#GO:0030048;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cardiac muscle cell action potential involved in contraction#GO:0086002;blood circulation#GO:0008015;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 myelin protein#PC00161 LEPOC|Ensembl=ENSLOCG00000000537.1|UniProtKB=W5LWT6 W5LWT6 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000009919.1|UniProtKB=W5MUS0 W5MUS0 PTHR11492:SF6 NUCLEAR FACTOR I NUCLEAR FACTOR 1 A-TYPE DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009641.1|UniProtKB=W5MTS4 W5MTS4 PTHR24339:SF32 HOMEOBOX PROTEIN EMX-RELATED VENTRAL ANTERIOR HOMEOBOX 1 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;animal organ development#GO:0048513;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;developmental process#GO:0032502;nervous system development#GO:0007399;head development#GO:0060322;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000004621.1|UniProtKB=W5MAX8 W5MAX8 PTHR16181:SF30 PROTEIN FAM83A-RELATED PROTEIN FAM83D protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;protein localization to cytoskeleton#GO:0044380;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;cell communication#GO:0007154;localization#GO:0051179;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell communication#GO:0010646;regulation of response to stimulus#GO:0048583;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;positive regulation of cellular process#GO:0048522;protein localization to microtubule cytoskeleton#GO:0072698;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;cytoplasm#GO:0005737;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitotic spindle pole#GO:0097431;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000017786.1|UniProtKB=W5NMN1 W5NMN1 PTHR14499:SF29 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD12 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 developmental process#GO:0032502;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;regulation of neuron projection development#GO:0010975;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of dendrite morphogenesis#GO:0048814;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773 presynaptic active zone membrane#GO:0048787;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynaptic membrane#GO:0045211;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;cell junction#GO:0030054;presynaptic active zone#GO:0048786 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000011808.1|UniProtKB=W5N1L4 W5N1L4 PTHR34529:SF1 AP-1 COMPLEX-ASSOCIATED REGULATORY PROTEIN AP-1 COMPLEX-ASSOCIATED REGULATORY PROTEIN binding#GO:0005488;protein-containing complex binding#GO:0044877 intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;Golgi to endosome transport#GO:0006895;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;transport vesicle#GO:0030133;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000009131.1|UniProtKB=W5MRX5 W5MRX5 CPEB4 PTHR12566:SF2 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 4 translation regulator activity#GO:0045182;mRNA 3'-UTR binding#GO:0003730;translation factor activity#GO:0180051;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of translation#GO:0017148;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 neuron projection#GO:0043005;nucleus#GO:0005634;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054 mRNA polyadenylation factor#PC00146 LEPOC|Ensembl=ENSLOCG00000011493.1|UniProtKB=W5N0G1 W5N0G1 PTHR24232:SF22 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 4 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Blood coagulation#P00011>PAR-4#P00461 LEPOC|Ensembl=ENSLOCG00000013098.1|UniProtKB=W5N691 W5N691 PTHR11199:SF10 STROMAL ANTIGEN COHESIN SUBUNIT SA-3 ISOFORM X1 chromatin binding#GO:0003682;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000005400.1|UniProtKB=W5MDS1 W5MDS1 PTHR11388:SF14 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1 active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 cellular process#GO:0009987;macromolecule localization#GO:0033036;lipid transport#GO:0006869;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;fatty acid transport#GO:0015908 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002377.1|UniProtKB=W5M378 W5M378 PTHR10856:SF20 CORONIN CORONIN-7 binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cell motility#GO:0048870;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;positive regulation of signal transduction#GO:0009967;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;supramolecular fiber organization#GO:0097435;regulation of intracellular signal transduction#GO:1902531;actin filament-based process#GO:0030029;regulation of signaling#GO:0023051 organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;actin filament#GO:0005884 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000000095.1|UniProtKB=W5LVE8 W5LVE8 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000002352.1|UniProtKB=W5M2Z5 W5M2Z5 PTHR26451:SF871 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN LOW QUALITY PROTEIN: ODORANT RECEPTOR 125-6-RELATED binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to chemical#GO:0042221;response to stimulus#GO:0050896;sensory perception of smell#GO:0007608;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002847.1|UniProtKB=W5M4P3 W5M4P3 PTHR23288:SF37 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL MARVEL DOMAIN CONTAINING 2-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;regulation of DNA-templated transcription elongation#GO:0032784;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;positive regulation of DNA-templated transcription, elongation#GO:0032786;snRNA transcription#GO:0009301;regulation of transcription by RNA polymerase II#GO:0006357;cell-cell junction assembly#GO:0007043;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;gene expression#GO:0010467;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;snRNA metabolic process#GO:0016073;regulation of DNA-templated transcription#GO:0006355;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;cell-cell junction organization#GO:0045216;transcription by RNA polymerase II#GO:0006366;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;intracellular vesicle#GO:0097708;organelle lumen#GO:0043233;vesicle#GO:0031982;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;apical junction complex#GO:0043296;apical part of cell#GO:0045177;cell junction#GO:0030054;nuclear protein-containing complex#GO:0140513;tight junction#GO:0070160;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;cell-cell junction#GO:0005911;cell periphery#GO:0071944;nucleus#GO:0005634;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000015578.1|UniProtKB=W5NEX1 W5NEX1 PTHR46555:SF1 UBIQUITIN-LIKE PROTEIN 4A UBIQUITIN-LIKE PROTEIN 4A LEPOC|Ensembl=ENSLOCG00000001666.1|UniProtKB=W5M0M0 W5M0M0 PTHR12875:SF3 GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000011270.1|UniProtKB=W5MZP7 W5MZP7 PTHR45851:SF1 MYC PROTO-ONCOGENE MYC PROTO-ONCOGENE PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;positive regulation of cell population proliferation#GO:0008284;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 CCKR signaling map#P06959>MYC#G06979;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;PDGF signaling pathway#P00047>c-Myc#P01172;Oxidative stress response#P00046>Myc#P01124;p53 pathway feedback loops 2#P04398>Myc#P04649;CCKR signaling map#P06959>MYC#G07272;Interleukin signaling pathway#P00036>c-Myc#P00995 LEPOC|Ensembl=ENSLOCG00000014355.1|UniProtKB=W5NAL9 W5NAL9 PTHR23288:SF12 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL2 binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;snRNA metabolic process#GO:0016073;regulation of DNA-templated transcription#GO:0006355;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;transcription by RNA polymerase II#GO:0006366;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;positive regulation of RNA biosynthetic process#GO:1902680;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;nucleic acid biosynthetic process#GO:0141187;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;positive regulation of DNA-templated transcription, elongation#GO:0032786;snRNA transcription#GO:0009301;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000001629.1|UniProtKB=W5M0J2 W5M0J2 PTHR21357:SF6 FAM172 FAMILY PROTEIN HOMOLOG CG10038 COTRANSCRIPTIONAL REGULATOR ARB2A HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000002463.1|UniProtKB=W5M3D9 W5M3D9 PTHR43544:SF39 SHORT-CHAIN DEHYDROGENASE/REDUCTASE NADB-LER2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002906.1|UniProtKB=W5M4X4 W5M4X4 PTHR24061:SF418 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000010499.1|UniProtKB=W5MWW3 W5MWW3 PTHR45755:SF1 FAMILY NOT NAMED PROTON-COUPLED ZINC ANTIPORTER SLC30A5 transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;zinc ion transmembrane transport#GO:0071577 intracellular vesicle#GO:0097708;Golgi stack#GO:0005795;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;Golgi cis cisterna#GO:0000137;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000005619.1|UniProtKB=W5MEJ1 W5MEJ1 PTHR31191:SF4 CENTROSOMAL PROTEIN CEP126 CENTROSOMAL PROTEIN OF 126 KDA cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;cytoplasmic microtubule organization#GO:0031122;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;ciliary base#GO:0097546;intracellular membraneless organelle#GO:0043232;cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;midbody#GO:0030496;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000002414.1|UniProtKB=W5M373 W5M373 PTHR10412:SF11 MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;alpha-glucosidase activity#GO:0090599;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 glucosidase#PC00108;hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000007656.1|UniProtKB=W5MLM6 W5MLM6 PTHR31383:SF2 OXIDATIVE STRESS-RESPONSE SERINE-RICH PROTEIN 1 OXIDATIVE STRESS-RESPONSIVE SERINE-RICH PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006628.1|UniProtKB=W5MHZ5 W5MHZ5 PTHR22624:SF38 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4C hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 macroautophagy#GO:0016236;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome assembly#GO:0000045;macromolecule metabolic process#GO:0043170;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;protein metabolic process#GO:0019538;proteolysis#GO:0006508;organelle assembly#GO:0070925 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000012348.1|UniProtKB=W5N3J2 W5N3J2 PTHR13243:SF1 HSPC111 PROTEIN-RELATED NUCLEOLAR PROTEIN 16 ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000006149.1|UniProtKB=W5MGB9 W5MGB9 PTHR47130:SF1 SI:DKEY-19B23.11-RELATED ZP DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000011522.1|UniProtKB=W5N0K4 W5N0K4 PTHR10336:SF33 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-3 lipase activity#GO:0016298;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143 5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 LEPOC|Ensembl=ENSLOCG00000012689.1|UniProtKB=W5N4Q7 W5N4Q7 PTHR11716:SF110 PHOSPHOLIPASE A2 FAMILY MEMBER OTOCONIN-90 PRECURSOR A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;lipid binding#GO:0008289;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;hydrolase activity, acting on ester bonds#GO:0016788;phospholipid binding#GO:0005543;catalytic activity#GO:0003824;cation binding#GO:0043169;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;small molecule binding#GO:0036094;lipase activity#GO:0016298;ion binding#GO:0043167 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;phosphatidylcholine metabolic process#GO:0046470;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phosphatidylglycerol metabolic process#GO:0046471 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000010745.1|UniProtKB=W5MXQ4 W5MXQ4 PTHR12441:SF10 ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT F6, MITOCHONDRIAL transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;proton-transporting ATP synthase complex#GO:0045259;respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796 ATP synthase#PC00002;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000001179.1|UniProtKB=W5LYW9 W5LYW9 PTHR24230:SF55 G-PROTEIN COUPLED RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 2 transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002612.1|UniProtKB=W5M3W1 W5M3W1 PTHR19818:SF84 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN GLIS2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000014616.1|UniProtKB=W5NBH5 W5NBH5 PTHR24366:SF99 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 3 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000013665.1|UniProtKB=W5N888 W5N888 PTHR12489:SF14 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 4 PROTEIN protein binding#GO:0005515;GABA receptor binding#GO:0050811;signaling receptor binding#GO:0005102;binding#GO:0005488 macromolecule localization#GO:0033036;cellular process#GO:0009987;multicellular organismal process#GO:0032501;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840;system process#GO:0003008;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;cell junction organization#GO:0034330;sensory perception of sound#GO:0007605;postsynapse organization#GO:0099173;nervous system process#GO:0050877;synapse organization#GO:0050808;localization within membrane#GO:0051668;sensory perception#GO:0007600;receptor clustering#GO:0043113;sensory perception of mechanical stimulus#GO:0050954;cellular localization#GO:0051641;localization#GO:0051179 plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008073.1|UniProtKB=W5MN42 W5MN42 PTHR19282:SF216 TETRASPANIN TETRASPANIN-1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000000805.1|UniProtKB=W5LXQ5 W5LXQ5 PTHR19944:SF62 MHC CLASS II-RELATED BETA-2-MICROGLOBULIN peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488;protein-containing complex binding#GO:0044877 regulation of cell adhesion#GO:0030155;positive regulation of response to stimulus#GO:0048584;positive regulation of cell activation#GO:0050867;positive regulation of leukocyte cell-cell adhesion#GO:1903039;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell adhesion#GO:0045785;antigen processing and presentation#GO:0019882;positive regulation of lymphocyte activation#GO:0051251;regulation of immune response#GO:0050776;regulation of T cell activation#GO:0050863;positive regulation of T cell activation#GO:0050870;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;cellular component biogenesis#GO:0044085;positive regulation of cell-cell adhesion#GO:0022409;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;positive regulation of leukocyte activation#GO:0002696;regulation of lymphocyte activation#GO:0051249;cellular component organization#GO:0016043;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;positive regulation of multicellular organismal process#GO:0051240;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;immune system process#GO:0002376 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000012763.1|UniProtKB=W5N4Z3 W5N4Z3 PTHR31530:SF2 MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 MINAR1 FAMILY MEMBER MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of cell population proliferation#GO:0008285;regulation of TOR signaling#GO:0032006;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cell population proliferation#GO:0042127;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000002722.1|UniProtKB=W5M499 W5M499 PTHR43544:SF39 SHORT-CHAIN DEHYDROGENASE/REDUCTASE NADB-LER2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000002420.1|UniProtKB=W5M382 W5M382 PTHR26451:SF345 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;detection of chemical stimulus#GO:0009593;system process#GO:0003008;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception of chemical stimulus#GO:0007606;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000017181.1|UniProtKB=W5NKS6 W5NKS6 PTHR46129:SF3 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN-14 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000003122.1|UniProtKB=W5M5M0 W5M5M0 PTHR12822:SF4 PROTEIN YIPF PROTEIN YIPF1 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000004891.1|UniProtKB=W5MBY2 W5MBY2 PTHR44598:SF2 JUNCTIONAL ADHESION MOLECULE C JUNCTIONAL ADHESION MOLECULE C cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000007494.1|UniProtKB=W5ML42 W5ML42 PTHR22590:SF4 MYOSIN MOTOR DOMAIN-CONTAINING PROTEIN ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN LEPOC|Ensembl=ENSLOCG00000006899.1|UniProtKB=W5MJ10 W5MJ10 PTHR11920:SF300 GUANYLYL CYCLASE ATRIAL NATRIURETIC PEPTIDE RECEPTOR 1 lyase activity#GO:0016829;molecular transducer activity#GO:0060089;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;peptide receptor activity#GO:0001653;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023 nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 lyase#PC00144;guanylate cyclase#PC00114 LEPOC|Ensembl=ENSLOCG00000012793.1|UniProtKB=W5N535 W5N535 PTHR12013:SF0 SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;transport#GO:0006810;intracellular protein transport#GO:0006886;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein transmembrane transport#GO:0071806;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization within membrane#GO:0051668;protein targeting#GO:0006605 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001356.1|UniProtKB=W5LZJ0 W5LZJ0 PTHR23151:SF92 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED PYRUVATE DEHYDROGENASE PROTEIN X COMPONENT, MITOCHONDRIAL oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493 acetyltransferase#PC00038;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016919.1|UniProtKB=W5NJV6 W5NJV6 PTHR21245:SF11 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Q RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA stabilization#GO:0043489;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;positive regulation of biological process#GO:0048518;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of RNA stability#GO:0043487;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000000403.1|UniProtKB=W5LWE0 W5LWE0 PTHR24106:SF151 NACHT, LRR AND CARD DOMAINS-CONTAINING B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002909.1|UniProtKB=W5M4W7 W5M4W7 PTHR12047:SF3 FANCONI ANEMIA GROUP A PROTEIN FANCONI ANEMIA A intracellular organelle#GO:0043229;Fanconi anaemia nuclear complex#GO:0043240;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000004988.1|UniProtKB=W5MC94 W5MC94 PTHR10985:SF160 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HES FAMILY BHLH TRANSCRIPTION FACTOR 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;pattern specification process#GO:0007389;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;regulation of gene expression#GO:0010468;Notch signaling pathway#GO:0007219;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of neuron differentiation#GO:0045664;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cell surface receptor signaling pathway#GO:0007166;anterior/posterior pattern specification#GO:0009952;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of macromolecule biosynthetic process#GO:0010558 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 LEPOC|Ensembl=ENSLOCG00000004391.1|UniProtKB=W5MA37 W5MA37 PTHR11145:SF14 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER BTB_POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 3 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;post-translational protein modification#GO:0043687;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;regulation of small GTPase mediated signal transduction#GO:0051056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;regulation of Rho protein signal transduction#GO:0035023;negative regulation of biological process#GO:0048519;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001957.1|UniProtKB=W5M1L6 W5M1L6 PTHR24083:SF41 NUCLEAR HORMONE RECEPTOR HEPATOCYTE NUCLEAR FACTOR 4-ALPHA signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000001029.1|UniProtKB=W5LYE6 W5LYE6 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;immune system process#GO:0002376;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;external side of plasma membrane#GO:0009897;cell periphery#GO:0071944;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000011446.1|UniProtKB=W5N0A8 W5N0A8 PTHR15706:SF20 SH3 MULTIPLE DOMAIN NEUTROPHIL CYTOSOL FACTOR 4 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 superoxide metabolic process#GO:0006801;cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006996.1|UniProtKB=W5MJB3 W5MJB3 PTHR13213:SF3 MYB-BINDING PROTEIN 1A FAMILY MEMBER MYB-BINDING PROTEIN 1A DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;transcription corepressor activity#GO:0003714;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004764.1|UniProtKB=W5MBF7 W5MBF7 PTHR11562:SF51 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER PROTON-COUPLED ZINC ANTIPORTER SLC30A2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;response to chemical#GO:0042221;response to metal ion#GO:0010038;transport#GO:0006810;establishment of localization#GO:0051234;metal ion transport#GO:0030001;response to stimulus#GO:0050896;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000000727.1|UniProtKB=W5LXE8 W5LXE8 PTHR13809:SF8 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-7 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 extrinsic component of membrane#GO:0019898;side of membrane#GO:0098552;extrinsic component of plasma membrane#GO:0019897;catalytic complex#GO:1902494;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 heterotrimeric G-protein#PC00117 Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Enkephalin release#P05913>G-Protein (s)#P05977;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (i)#P05974;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;GABA-B receptor II signaling#P05731>Ggamma#P05754;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;Wnt signaling pathway#P00057>Ggamma#P01465 LEPOC|Ensembl=ENSLOCG00000002970.1|UniProtKB=W5M539 W5M539 PTHR12882:SF1 SUPPRESSOR OF TY 4 TRANSCRIPTION ELONGATION FACTOR SPT4 enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654 general transcription factor#PC00259;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000018103.1|UniProtKB=W5NNJ5 W5NNJ5 PTHR24230:SF84 G-PROTEIN COUPLED RECEPTOR UROTENSIN-2 RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000013248.1|UniProtKB=W5N6R2 W5N6R2 PTHR15593:SF1 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 6 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of response to external stimulus#GO:0032101;regulation of natural killer cell mediated cytotoxicity#GO:0042269;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of innate immune response#GO:0045088;cellular response to stimulus#GO:0051716;regulation of natural killer cell mediated immunity#GO:0002715;regulation of leukocyte mediated immunity#GO:0002703;regulation of biological process#GO:0050789;regulation of response to biotic stimulus#GO:0002831;signaling#GO:0023052;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to stimulus#GO:0050896;regulation of defense response#GO:0031347;regulation of cell killing#GO:0031341;regulation of immune response#GO:0050776;regulation of lymphocyte mediated immunity#GO:0002706;G protein-coupled receptor signaling pathway#GO:0007186;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;cell communication#GO:0007154 extrinsic component of membrane#GO:0019898;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Endothelin signaling pathway#P00019>PI3K#P00577;EGF receptor signaling pathway#P00018>PI3K#P00557 LEPOC|Ensembl=ENSLOCG00000010774.1|UniProtKB=W5MXU3 W5MXU3 PTHR13948:SF21 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 5 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000009726.1|UniProtKB=W5MU36 W5MU36 PTHR45653:SF6 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 2 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 striated muscle cell differentiation#GO:0051146;syncytium formation by cell-cell fusion#GO:0000768;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;developmental process#GO:0032502;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;cell migration#GO:0016477;cell motility#GO:0048870;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;myoblast fusion#GO:0007520 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000009891.1|UniProtKB=W5MUN5 W5MUN5 PTHR24100:SF130 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1-LIKE ISOFORM X1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to stimulus#GO:0048584;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;T cell receptor signaling pathway#GO:0050852;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of immune response#GO:0050776;regulation of multicellular organismal process#GO:0051239;antigen receptor-mediated signaling pathway#GO:0050851;positive regulation of biological process#GO:0048518;activation of immune response#GO:0002253;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of immune system process#GO:0002684;immune response-activating signaling pathway#GO:0002757;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;immune system process#GO:0002376 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 LEPOC|Ensembl=ENSLOCG00000015611.1|UniProtKB=W5NF10 W5NF10 PTHR15176:SF1 NEPHROCYSTIN NEPHROCYSTIN-1 cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;cellular process#GO:0009987;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary base#GO:0097546;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;ciliary transition zone#GO:0035869 cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000003958.1|UniProtKB=W5M8L8 W5M8L8 PTHR11232:SF80 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER CARBOXYL-TERMINAL PDZ LIGAND OF NEURONAL NITRIC OXIDE SYNTHASE PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013972.1|UniProtKB=W5N9B4 W5N9B4 PTHR11375:SF25 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000004387.1|UniProtKB=W5MA33 W5MA33 PTHR18976:SF1 APOLIPOPROTEIN APOLIPOPROTEIN A-IV molecular function activator activity#GO:0140677;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;enzyme regulator activity#GO:0030234;binding#GO:0005488;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;cholesterol transfer activity#GO:0120020;molecular function regulator activity#GO:0098772;sterol transfer activity#GO:0120015;transporter activity#GO:0005215;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047 establishment of localization#GO:0051234;sterol metabolic process#GO:0016125;sterol transport#GO:0015918;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;transport#GO:0006810;cholesterol metabolic process#GO:0008203;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;lipid transport#GO:0006869;phospholipid transport#GO:0015914;steroid metabolic process#GO:0008202;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cellular process#GO:0009987;cholesterol efflux#GO:0033344;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;small molecule metabolic process#GO:0044281;organophosphate ester transport#GO:0015748;homeostatic process#GO:0042592;secondary alcohol metabolic process#GO:1902652;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238 vesicle#GO:0031982;very-low-density lipoprotein particle#GO:0034361;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;lipoprotein particle#GO:1990777;extracellular protein-containing complex#GO:0140392;protein-lipid complex#GO:0032994;extracellular region#GO:0005576;high-density lipoprotein particle#GO:0034364;membrane-bounded organelle#GO:0043227;plasma lipoprotein particle#GO:0034358 transfer/carrier protein#PC00219;apolipoprotein#PC00052 LEPOC|Ensembl=ENSLOCG00000009706.1|UniProtKB=W5MTZ3 W5MTZ3 PTHR12210:SF43 DULLARD PROTEIN PHOSPHATASE CTD SMALL PHOSPHATASE-LIKE PROTEIN phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195 LEPOC|Ensembl=ENSLOCG00000006412.1|UniProtKB=W5MHB2 W5MHB2 PTHR12988:SF6 SPHINGOMYELIN PHOSPHODIESTERASE 4 SPHINGOMYELIN PHOSPHODIESTERASE 4 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 organophosphate catabolic process#GO:0046434;ceramide metabolic process#GO:0006672;glycerolipid catabolic process#GO:0046503;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;phosphorus metabolic process#GO:0006793;glycerophospholipid catabolic process#GO:0046475;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987 phosphodiesterase#PC00185 LEPOC|Ensembl=ENSLOCG00000012852.1|UniProtKB=W5N5B2 W5N5B2 PTHR11207:SF37 RIBONUCLEASE III RIBONUCLEASE 3 RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725 negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;primary miRNA processing#GO:0031053;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;endoribonuclease#PC00094 LEPOC|Ensembl=ENSLOCG00000000716.1|UniProtKB=W5LXE0 W5LXE0 PTHR14948:SF21 NG5 PROLINE-RICH TRANSMEMBRANE PROTEIN 1 signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002859.1|UniProtKB=W5M4Q2 W5M4Q2 PTHR14356:SF2 INTERLEUKIN-15-RELATED INTERLEUKIN-21 positive regulation of response to external stimulus#GO:0032103;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of lymphocyte mediated immunity#GO:0002706;regulation of cell killing#GO:0031341;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of innate immune response#GO:0045088;regulation of gene expression#GO:0010468;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of gene expression#GO:0010628;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;positive regulation of response to stimulus#GO:0048584;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of cytokine production#GO:0001817;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;regulation of immune effector process#GO:0002697;positive regulation of biosynthetic process#GO:0009891;positive regulation of lymphocyte mediated immunity#GO:0002708;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of cellular process#GO:0050794;positive regulation of cytokine production#GO:0001819;regulation of immune system process#GO:0002682;regulation of macromolecule metabolic process#GO:0060255;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of response to biotic stimulus#GO:0002831;regulation of natural killer cell mediated immunity#GO:0002715;regulation of leukocyte mediated immunity#GO:0002703 cytokine#PC00083;interleukin superfamily#PC00128;intercellular signal molecule#PC00207 Interleukin signaling pathway#P00036>Interleukin#P00970 LEPOC|Ensembl=ENSLOCG00000012794.1|UniProtKB=W5N540 W5N540 PTHR18945:SF866 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-7 trans-synaptic signaling#GO:0099537;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 transmembrane transporter complex#GO:1902495;axon#GO:0030424;postsynaptic membrane#GO:0045211;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell body#GO:0044297;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;postsynapse#GO:0098794;cell junction#GO:0030054;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;presynapse#GO:0098793;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079 LEPOC|Ensembl=ENSLOCG00000000466.1|UniProtKB=W5LWK8 W5LWK8 PTHR45632:SF6 LD33804P KELCH-LIKE PROTEIN 14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 neuron projection#GO:0043005;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;cell body#GO:0044297;cell projection#GO:0042995;cullin-RING ubiquitin ligase complex#GO:0031461;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006835.1|UniProtKB=W5MIQ6 W5MIQ6 PTHR11304:SF5 EPHRIN EPHRIN-A3 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of cellular process#GO:0050794;ephrin receptor signaling pathway#GO:0048013;cellular response to stimulus#GO:0051716;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000013048.1|UniProtKB=W5N614 W5N614 PTHR12764:SF4 WD REPEAT DOMAIN-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to cilium#GO:0061512;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;protein localization to organelle#GO:0033365;intraciliary retrograde transport#GO:0035721;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cellular localization#GO:0051641 intraciliary transport particle#GO:0030990;cilium#GO:0005929;non-motile cilium#GO:0097730;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 LEPOC|Ensembl=ENSLOCG00000003310.1|UniProtKB=W5M6A5 W5M6A5 PTHR19818:SF131 ZINC FINGER PROTEIN ZIC AND GLI METAL REGULATORY TRANSCRIPTION FACTOR 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000007524.1|UniProtKB=W5ML76 W5ML76 PTHR16154:SF26 NEURABIN NEURABIN-1 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein-containing complex binding#GO:0044877;protein-membrane adaptor activity#GO:0043495;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;intracellular signal transduction#GO:0035556;system development#GO:0048731;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cell communication#GO:0007154;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neurogenesis#GO:0022008;calcium-mediated signaling#GO:0019722;actin filament organization#GO:0007015;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;neuron projection development#GO:0031175;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 neuron projection#GO:0043005;cell periphery#GO:0071944;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;cell cortex#GO:0005938;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;postsynapse#GO:0098794;cortical cytoskeleton#GO:0030863;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;postsynaptic density#GO:0014069;filopodium#GO:0030175;dendrite#GO:0030425;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012095.1|UniProtKB=W5N2Q2 W5N2Q2 PTHR11039:SF39 NEBULIN NEBULIN-RELATED-ANCHORING PROTEIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 developmental process#GO:0032502;cellular developmental process#GO:0048869;cardiac muscle tissue development#GO:0048738;actin filament organization#GO:0007015;tissue development#GO:0009888;multicellular organismal process#GO:0032501;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;system development#GO:0048731;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cellular anatomical entity morphogenesis#GO:0032989;striated muscle tissue development#GO:0014706;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heart development#GO:0007507;cytoskeleton organization#GO:0007010;cardiac muscle cell differentiation#GO:0055007;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;circulatory system development#GO:0072359;actomyosin structure organization#GO:0031032;cell development#GO:0048468 supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;Z disc#GO:0030018;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;I band#GO:0031674 LEPOC|Ensembl=ENSLOCG00000015166.1|UniProtKB=W5NDF5 W5NDF5 PTHR16206:SF10 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 4 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000006227.1|UniProtKB=W5MGK8 W5MGK8 PTHR11592:SF5 GLUTATHIONE PEROXIDASE PROTEIN PEROXIDASE GPX7 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824 cellular response to oxidative stress#GO:0034599;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554 oxidoreductase#PC00176;peroxidase#PC00180 LEPOC|Ensembl=ENSLOCG00000017507.1|UniProtKB=W5NLV3 W5NLV3 PTHR19290:SF171 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;plasma membrane bounded cell projection organization#GO:0120036;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;positive regulation of macromolecule metabolic process#GO:0010604;head development#GO:0060322;nervous system development#GO:0007399;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;central nervous system development#GO:0007417;forebrain development#GO:0030900;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000003424.1|UniProtKB=W5M6T9 W5M6T9 PTHR11654:SF89 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 1 oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;oligopeptide transport#GO:0006857;transmembrane transport#GO:0055085;import into cell#GO:0098657;dipeptide transport#GO:0042938;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;oligopeptide transmembrane transport#GO:0035672;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;import across plasma membrane#GO:0098739 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000002971.1|UniProtKB=W5M540 W5M540 PTHR43658:SF5 SHORT-CHAIN DEHYDROGENASE/REDUCTASE SI:DKEY-238O13.4 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;hormone metabolic process#GO:0042445;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;estrogen metabolic process#GO:0008210;regulation of biological quality#GO:0065008;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012132.1|UniProtKB=W5N2R3 W5N2R3 PTHR11848:SF165 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 4 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;heart development#GO:0007507;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular response to endogenous stimulus#GO:0071495;circulatory system development#GO:0072359;response to stimulus#GO:0050896;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cellular response to growth factor stimulus#GO:0071363;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;developmental process#GO:0032502;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;heart morphogenesis#GO:0003007;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;system development#GO:0048731 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817;TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000011633.1|UniProtKB=W5N0Y4 W5N0Y4 PTHR12879:SF21 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE_C4-MONOOXYGENASE DES2 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;ceramide metabolic process#GO:0006672 hydroxylase#PC00122;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000013382.1|UniProtKB=W5N794 W5N794 PTHR24060:SF98 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 7 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 LEPOC|Ensembl=ENSLOCG00000014336.1|UniProtKB=W5NAJ5 W5NAJ5 EIF3K PTHR13022:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 eukaryotic translation initiation factor 3 complex#GO:0005852;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 LEPOC|Ensembl=ENSLOCG00000008660.1|UniProtKB=W5MQ89 W5MQ89 PTHR24347:SF460 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE DCLK2 ISOFORM X1-RELATED protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000009199.1|UniProtKB=W5MS65 W5MS65 PTHR13025:SF8 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN FAMILY, MEMBER D1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000013758.1|UniProtKB=W5N8L4 W5N8L4 PTHR43272:SF116 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 1 ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;long-chain fatty acid metabolic process#GO:0001676;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 ligase#PC00142 LEPOC|Ensembl=ENSLOCG00000003756.1|UniProtKB=W5M7X5 W5M7X5 PTHR23512:SF13 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 LYSOSOMAL DIPEPTIDE TRANSPORTER MFSD1 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;lysosome#GO:0005764 LEPOC|Ensembl=ENSLOCG00000007863.1|UniProtKB=W5MME6 W5MME6 PTHR11225:SF4 NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP93 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 protein transport#GO:0015031;protein import into nucleus#GO:0006606;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017571.1|UniProtKB=W5NM17 W5NM17 PTHR26453:SF665 OLFACTORY RECEPTOR OLFACTORY RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 system process#GO:0003008;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;response to chemical#GO:0042221;response to stimulus#GO:0050896;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013425.1|UniProtKB=W5N7F7 W5N7F7 PTHR12848:SF22 REGULATORY-ASSOCIATED PROTEIN OF MTOR REGULATORY-ASSOCIATED PROTEIN OF MTOR protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of catabolic process#GO:0009894;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of growth#GO:0040008;positive regulation of cell growth#GO:0030307;regulation of cell growth#GO:0001558;response to chemical#GO:0042221;TOR signaling#GO:0031929;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to acid chemical#GO:0001101;TORC1 signaling#GO:0038202;positive regulation of growth#GO:0045927;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;signaling#GO:0023052;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;TOR complex#GO:0038201;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000001640.1|UniProtKB=W5M0K1 W5M0K1 POR PTHR19384:SF17 NITRIC OXIDE SYNTHASE-RELATED NADPH--CYTOCHROME P450 REDUCTASE small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>P450 reductase#P04605 LEPOC|Ensembl=ENSLOCG00000009409.1|UniProtKB=W5MSX2 W5MSX2 PTHR10489:SF942 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 2 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;protein binding#GO:0005515;molecular transducer activity#GO:0060089;cytokine receptor activity#GO:0004896;immune receptor activity#GO:0140375;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;cytokine binding#GO:0019955 intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;cell migration#GO:0016477;taxis#GO:0042330;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;immune response#GO:0006955;calcium-mediated signaling#GO:0019722;response to external stimulus#GO:0009605;locomotion#GO:0040011;signaling#GO:0023052;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;cell chemotaxis#GO:0060326;cell communication#GO:0007154;chemotaxis#GO:0006935;cellular response to chemical stimulus#GO:0070887;positive regulation of cytosolic calcium ion concentration#GO:0007204;immune system process#GO:0002376 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000001821.1|UniProtKB=W5M160 W5M160 PTHR11947:SF39 PYRUVATE DEHYDROGENASE KINASE PROTEIN-SERINE_THREONINE KINASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of carbohydrate metabolic process#GO:0006109;regulation of lipid metabolic process#GO:0019216 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003160.1|UniProtKB=W5M5S2 W5M5S2 PTHR31180:SF2 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107 cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;cilium#GO:0005929;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;axoneme#GO:0005930;cytoplasmic microtubule#GO:0005881;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879 LEPOC|Ensembl=ENSLOCG00000017512.1|UniProtKB=W5NLV8 W5NLV8 PTHR28649:SF3 PROTEIN REPRIMO-RELATED REPRIMO-LIKE PROTEIN LEPOC|Ensembl=ENSLOCG00000000910.1|UniProtKB=W5LY08 W5LY08 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000002874.1|UniProtKB=W5M4S3 W5M4S3 PTHR11568:SF4 HEPATOCYTE NUCLEAR FACTOR 1 HEPATOCYTE NUCLEAR FACTOR 1-ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010053.1|UniProtKB=W5MV94 W5MV94 PTHR22734:SF3 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 RIBOSOME PRODUCTION FACTOR 1 rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000008893.1|UniProtKB=W5MR25 W5MR25 PTHR12436:SF39 80 KDA MCM3-ASSOCIATED PROTEIN GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription export complex 2#GO:0070390;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000015882.1|UniProtKB=W5NFZ8 W5NFZ8 PTHR10300:SF5 CALCIPRESSIN CALCIPRESSIN-2 enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000015834.1|UniProtKB=W5NFT4 W5NFT4 PTHR45884:SF3 N-ACETYLTRANSFERASE ECO N-ACETYLTRANSFERASE ESCO2 protein N-acyltransferase activity#GO:0140186;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740 chromosome organization#GO:0051276;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;mitotic sister chromatid cohesion#GO:0007064;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000012519.1|UniProtKB=W5N454 W5N454 PTHR23147:SF189 SERINE/ARGININE RICH SPLICING FACTOR SERINE AND ARGININE-RICH-SPLICING FACTOR 3A-RELATED supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000004489.1|UniProtKB=W5MAJ0 W5MAJ0 PTHR21573:SF0 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;EMC complex#GO:0072546;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 LEPOC|Ensembl=ENSLOCG00000007860.1|UniProtKB=W5MME7 W5MME7 PTHR23142:SF2 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38B RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681 LEPOC|Ensembl=ENSLOCG00000001778.1|UniProtKB=W5M153 W5M153 PTHR10574:SF444 NETRIN/LAMININ-RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN developmental process#GO:0032502;tissue development#GO:0009888;anatomical structure development#GO:0048856 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000012690.1|UniProtKB=W5N4Q6 W5N4Q6 PTHR33768:SF5 MIP11318P SPERM AXONEMAL MAINTENANCE PROTEIN CFAP97D1 LEPOC|Ensembl=ENSLOCG00000015931.1|UniProtKB=W5NG62 W5NG62 PTHR22838:SF28 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 26 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 LEPOC|Ensembl=ENSLOCG00000008371.1|UniProtKB=W5MP58 W5MP58 PTHR14102:SF3 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG GAMMA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytoskeleton organization#GO:0007010;cell junction organization#GO:0034330;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cell-cell junction maintenance#GO:0045217;microtubule cytoskeleton organization#GO:0000226;cell-cell junction organization#GO:0045216;establishment or maintenance of cell polarity#GO:0007163 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;apical plasma membrane#GO:0016324;cell cortex#GO:0005938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;apical part of cell#GO:0045177;transferase complex#GO:1990234;protein kinase complex#GO:1902911;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737 tight junction#PC00214;cell junction protein#PC00070 LEPOC|Ensembl=ENSLOCG00000016070.1|UniProtKB=W5NGP2 W5NGP2 PTHR11848:SF320 TGF-BETA FAMILY NODAL-RELATED 1-RELATED signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 LEPOC|Ensembl=ENSLOCG00000015353.1|UniProtKB=W5NE35 W5NE35 PTHR43557:SF4 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;small molecule binding#GO:0036094;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;oxidoreductase activity, acting on NAD(P)H#GO:0016651 programmed cell death#GO:0012501;establishment of localization in cell#GO:0051649;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987;mitochondrial transport#GO:0006839;mitochondrial protein import pathway#GO:7770058;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 Apoptosis signaling pathway#P00006>AIF#P00286 LEPOC|Ensembl=ENSLOCG00000006784.1|UniProtKB=W5MII8 W5MII8 PTHR12771:SF18 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 1 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 intracellular organelle#GO:0043229;cilium#GO:0005929;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;synapse#GO:0045202 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000007594.1|UniProtKB=W5MLH2 W5MLH2 PTHR24345:SF98 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047 condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;membraneless organelle#GO:0043228;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;spindle pole#GO:0000922;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000017365.1|UniProtKB=W5NLG1 W5NLG1 PTHR15139:SF0 TUBULIN FOLDING COFACTOR C TUBULIN-SPECIFIC CHAPERONE C cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004858.1|UniProtKB=W5MBS3 W5MBS3 PTHR19411:SF0 PROTEIN BUD31-RELATED PROTEIN BUD31 HOMOLOG gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000009898.1|UniProtKB=W5MUP1 W5MUP1 PTHR24073:SF572 DRAB5-RELATED RAS-RELATED PROTEIN RAB-28 hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000005789.1|UniProtKB=W5MF31 W5MF31 PTHR24254:SF10 PROTHROMBIN PROTHROMBIN serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;hemostasis#GO:0007599;regulation of wound healing#GO:0061041;regulation of body fluid levels#GO:0050878;response to stimulus#GO:0050896;regulation of blood coagulation#GO:0030193;cell activation#GO:0001775;positive regulation of coagulation#GO:0050820;regulation of biological quality#GO:0065008;wound healing#GO:0042060;cellular process#GO:0009987;regulation of hemostasis#GO:1900046;positive regulation of biological process#GO:0048518;coagulation#GO:0050817;response to stress#GO:0006950;response to wounding#GO:0009611;regulation of response to wounding#GO:1903034;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of response to external stimulus#GO:0032101;positive regulation of response to stimulus#GO:0048584;regulation of coagulation#GO:0050818;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;blood coagulation#GO:0007596;platelet activation#GO:0030168 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 Blood coagulation#P00011>Prothrombin#P00416;Blood coagulation#P00011>Thrombin#P00414 LEPOC|Ensembl=ENSLOCG00000006635.1|UniProtKB=W5MI02 W5MI02 PTHR31539:SF1 CENTROSOMAL PROTEIN OF 19K CEP19 CENTROSOMAL PROTEIN OF 19 KDA localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;cilium organization#GO:0044782;trans-Golgi to periciliary membrane compartment transport#GO:0097712;organelle assembly#GO:0070925;localization within membrane#GO:0051668;Golgi to plasma membrane transport#GO:0006893;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393;establishment of localization#GO:0051234;microtubule anchoring#GO:0034453;vesicle-mediated transport to the plasma membrane#GO:0098876;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819 LEPOC|Ensembl=ENSLOCG00000005407.1|UniProtKB=W5MDR3 W5MDR3 PTHR45665:SF11 AQUAPORIN-8 AQUAPORIN-8A.2-RELATED channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250 establishment of localization#GO:0051234;water transport#GO:0006833;localization#GO:0051179;fluid transport#GO:0042044;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000013200.1|UniProtKB=W5N6J9 W5N6J9 PTHR22999:SF40 PX SERINE/THREONINE KINASE PXK PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000007021.1|UniProtKB=W5MJE2 W5MJE2 PTHR10809:SF12 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN B_C protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum membrane organization#GO:0090158;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;membrane organization#GO:0061024 organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000009365.1|UniProtKB=W5MSR0 W5MSR0 PTHR31958:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 127 COILED-COIL DOMAIN-CONTAINING PROTEIN 127 LEPOC|Ensembl=ENSLOCG00000005854.1|UniProtKB=W5MFA6 W5MFA6 PTHR15009:SF4 MUELLERIAN-INHIBITING FACTOR ANTI-MUELLERIAN HORMONE cytokine receptor binding#GO:0005126;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 developmental process involved in reproduction#GO:0003006;anatomical structure morphogenesis#GO:0009653;reproductive process#GO:0022414;reproductive structure development#GO:0048608;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;reproductive system development#GO:0061458;system development#GO:0048731;sex differentiation#GO:0007548;multicellular organismal process#GO:0032501;gonad development#GO:0008406;development of primary male sexual characteristics#GO:0046546;male sex differentiation#GO:0046661;development of primary sexual characteristics#GO:0045137;developmental process#GO:0032502;animal organ development#GO:0048513;multicellular organism development#GO:0007275 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Gonadotropin-releasing hormone receptor pathway#P06664>MIS#P06750 LEPOC|Ensembl=ENSLOCG00000009510.1|UniProtKB=W5MTB6 W5MTB6 PTHR24353:SF155 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000015152.1|UniProtKB=W5NDD7 W5NDD7 PTHR15348:SF30 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3-RELATED DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000008086.1|UniProtKB=W5MN68 W5MN68 PTHR12395:SF9 DOM-3 RELATED DECAPPING AND EXORIBONUCLEASE PROTEIN catalytic activity, acting on RNA#GO:0140098;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity, acting on acid anhydrides#GO:0016817;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 RNA catabolic process#GO:0006401;RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000009619.1|UniProtKB=W5MTP4 W5MTP4 PTHR46258:SF2 LONGIN DOMAIN-CONTAINING PROTEIN VESICLE-TRAFFICKING PROTEIN SEC22C cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 LEPOC|Ensembl=ENSLOCG00000006431.1|UniProtKB=W5MHA7 W5MHA7 PTHR24067:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 R1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000012161.1|UniProtKB=W5N2U9 W5N2U9 PTHR23044:SF77 3'-5' EXONUCLEASE ERI1-RELATED 3'-5' EXORIBONUCLEASE 1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of cellular component organization#GO:0051129;rRNA processing#GO:0006364;positive regulation of biosynthetic process#GO:0009891;regulation of chromatin organization#GO:1902275;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 exoribonuclease#PC00099 LEPOC|Ensembl=ENSLOCG00000018072.1|UniProtKB=W5NNG4 W5NNG4 PTHR10903:SF107 GTPASE, IMAP FAMILY MEMBER-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0290503 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000000070.1|UniProtKB=W5LVC3 W5LVC3 PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED LEPOC|Ensembl=ENSLOCG00000015188.1|UniProtKB=W5NDI3 W5NDI3 PTHR13817:SF27 TITIN MYOSIN-BINDING PROTEIN C, SLOW-TYPE structural molecule activity#GO:0005198 sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;anatomical structure morphogenesis#GO:0009653;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 A band#GO:0031672;contractile muscle fiber#GO:0043292;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;M band#GO:0031430;intracellular organelle#GO:0043229;sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000008932.1|UniProtKB=W5MR69 W5MR69 PTHR24200:SF16 TOUCAN, ISOFORM A MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR 1 HOMOLOG A protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000018365.1|UniProtKB=W5NPA7 W5NPA7 PTHR10270:SF295 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;sensory system development#GO:0048880;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;eye development#GO:0001654;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;negative regulation of metabolic process#GO:0009892;sensory organ morphogenesis#GO:0090596;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;sensory organ development#GO:0007423;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;camera-type eye morphogenesis#GO:0048593;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;camera-type eye development#GO:0043010;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000003751.1|UniProtKB=W5M7V9 W5M7V9 PTHR24368:SF62 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 3 animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731;cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;brain development#GO:0007420;central nervous system development#GO:0007417;multicellular organismal process#GO:0032501;head development#GO:0060322;nervous system development#GO:0007399 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000002898.1|UniProtKB=W5M4U6 W5M4U6 PTHR13659:SF5 AUTOSOMAL HIGHLY CONSERVED PROTEIN PROTEIN FAM8A1 LEPOC|Ensembl=ENSLOCG00000012982.1|UniProtKB=W5N5U2 W5N5U2 PTHR21467:SF0 PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 PPP4R4 SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 cytosol#GO:0005829;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase modulator#PC00184 LEPOC|Ensembl=ENSLOCG00000009561.1|UniProtKB=W5MTH6 W5MTH6 PTHR22876:SF5 ZGC:101016 CHROMOSOME 9 OPEN READING FRAME 85 LEPOC|Ensembl=ENSLOCG00000005112.1|UniProtKB=W5MCP4 W5MCP4 PTHR13006:SF8 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 SLC2A4 REGULATOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000008015.1|UniProtKB=W5MMX5 W5MMX5 PTHR23192:SF36 OLFACTOMEDIN-RELATED NOELIN-3 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000014805.1|UniProtKB=W5NC69 W5NC69 PTHR10237:SF14 DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN MYND-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244 LEPOC|Ensembl=ENSLOCG00000008228.1|UniProtKB=W5MNN2 W5MNN2 PTHR14281:SF0 KINETOCHORE PROTEIN SPC25-RELATED KINETOCHORE PROTEIN SPC25 cell cycle#GO:0007049;chromosome segregation#GO:0007059;cellular process#GO:0009987;cell cycle process#GO:0022402 chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;outer kinetochore#GO:0000940;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;kinetochore#GO:0000776;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000015793.1|UniProtKB=W5NFN8 W5NFN8 PTHR21689:SF2 LIN-9 PROTEIN LIN-9 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000014285.1|UniProtKB=W5NAD1 W5NAD1 PTHR15382:SF2 CTG4A-RELATED PROTEIN CANOPY HOMOLOG 3 binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 LEPOC|Ensembl=ENSLOCG00000017172.1|UniProtKB=W5NKR6 W5NKR6 PTHR13063:SF10 ENOS INTERACTING PROTEIN NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001860.1|UniProtKB=W5M1B4 W5M1B4 PTHR10454:SF157 CASPASE CASPASE-9 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 positive regulation of apoptotic process#GO:0043065;apoptotic signaling pathway#GO:0097190;positive regulation of neuron apoptotic process#GO:0043525;DNA damage response#GO:0006974;regulation of apoptotic process#GO:0042981;biological regulation#GO:0065007;regulation of neuron apoptotic process#GO:0043523;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;protease#PC00190 PI3 kinase pathway#P00048>Caspase-9#P01197;FAS signaling pathway#P00020>Pro-Caspase9#P00603;VEGF signaling pathway#P00056>Caspase9#P01410;FAS signaling pathway#P00020>Caspase9#P00593;Angiogenesis#P00005>Caspase 9#P00216;Apoptosis signaling pathway#P00006>Caspase 9#P00298 LEPOC|Ensembl=ENSLOCG00000015157.1|UniProtKB=W5NDE6 W5NDE6 PTHR11486:SF77 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 13 transporter regulator activity#GO:0141108;binding#GO:0005488;signaling receptor binding#GO:0005102;channel regulator activity#GO:0016247;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;growth factor activity#GO:0008083;ion channel regulator activity#GO:0099106;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;fibroblast growth factor receptor binding#GO:0005104 neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of cell migration#GO:0030334;response to fibroblast growth factor#GO:0071774;regulation of locomotion#GO:0040012;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;fibroblast growth factor receptor signaling pathway#GO:0008543;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;nervous system development#GO:0007399;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 FGF signaling pathway#P00021>FGF#P00623 LEPOC|Ensembl=ENSLOCG00000015398.1|UniProtKB=W5NE86 W5NE86 PTHR10505:SF4 CALCITONIN-RELATED ISLET AMYLOID POLYPEPTIDE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 LEPOC|Ensembl=ENSLOCG00000009355.1|UniProtKB=W5MSQ6 W5MSQ6 PTHR13964:SF26 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4A binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000004980.1|UniProtKB=W5MC82 W5MC82 PTHR23073:SF155 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6B isomerase activity#GO:0016853;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 proteasome complex#GO:0000502;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protease#PC00190 Ubiquitin proteasome pathway#P00060>19S proteasome#P01494;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 LEPOC|Ensembl=ENSLOCG00000011997.1|UniProtKB=W5N2A3 W5N2A3 SORCS1 PTHR12106:SF52 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS1 ISOFORM X1 cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000004892.1|UniProtKB=W5MBX5 W5MBX5 PTHR45656:SF1 PROTEIN CBR-CLEC-78 SEIZURE PROTEIN 6 HOMOLOG developmental process#GO:0032502;regulation of cell projection organization#GO:0031344;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;nervous system development#GO:0007399;head development#GO:0060322;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;developmental maturation#GO:0021700;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of developmental process#GO:0050793;regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;central nervous system development#GO:0007417;regulation of cellular component organization#GO:0051128 neuron spine#GO:0044309;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dendritic spine#GO:0043197;cell body#GO:0044297;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;endomembrane system#GO:0012505;neuron projection#GO:0043005;cell junction#GO:0030054;endoplasmic reticulum#GO:0005783 LEPOC|Ensembl=ENSLOCG00000007164.1|UniProtKB=W5MJW4 W5MJW4 PTHR24060:SF30 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 5 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640 regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell surface receptor signaling pathway#GO:0007166;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634 G-protein coupled receptor#PC00021 Metabotropic glutamate receptor group I pathway#P00041>mGluR5#P01061;Metabotropic glutamate receptor group III pathway#P00039>mGluR 5#P01037;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Metabotropic glutamate receptor group I pathway#P00041>mGluR1#P01062;Endogenous cannabinoid signaling#P05730>mGluR#P05748;Metabotropic glutamate receptor group III pathway#P00039>mGluR 1/5#P01040;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 LEPOC|Ensembl=ENSLOCG00000008271.1|UniProtKB=W5MNW1 W5MNW1 PTHR10199:SF89 THROMBOSPONDIN THROMBOSPONDIN-3 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000009640.1|UniProtKB=W5MTS3 W5MTS3 PTHR31037:SF1 RELT-LIKE PROTEIN 1-RELATED RELT-LIKE PROTEIN 1 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;positive regulation of MAPK cascade#GO:0043410;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000003382.1|UniProtKB=W5M6J4 W5M6J4 PTHR18849:SF4 LEUCINE RICH REPEAT PROTEIN LEUCINE RICH REPEAT CONTAINING 77 LEPOC|Ensembl=ENSLOCG00000005110.1|UniProtKB=W5MCP2 W5MCP2 PTHR11935:SF80 BETA LACTAMASE DOMAIN HYDROXYACYLGLUTATHIONE HYDROLASE, MITOCHONDRIAL catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000015126.1|UniProtKB=W5NDA8 W5NDA8 PTHR22604:SF105 OXIDOREDUCTASES TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000000822.1|UniProtKB=W5LXQ6 W5LXQ6 PTHR21844:SF2 AKT1 SUBSTRATE 1 PROTEIN PROLINE-RICH AKT1 SUBSTRATE 1 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of TOR signaling#GO:0032006;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 CCKR signaling map#P06959>PRAS40#P07076 LEPOC|Ensembl=ENSLOCG00000003381.1|UniProtKB=W5M6J9 W5M6J9 PTHR46738:SF1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000011392.1|UniProtKB=W5N042 W5N042 PTHR45945:SF1 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G PROTEIN SIGNALING 12 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 LEPOC|Ensembl=ENSLOCG00000007595.1|UniProtKB=W5MLH3 W5MLH3 PTHR24208:SF95 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN LHX9 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000009885.1|UniProtKB=W5MUM4 W5MUM4 PTHR43247:SF1 PHOSPHOSERINE AMINOTRANSFERASE PHOSPHOSERINE AMINOTRANSFERASE transaminase activity#GO:0008483;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;transferase activity#GO:0016740 proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transaminase#PC00216 Vitamin B6 metabolism#P02787>Phosphoserine transaminase#P03227;Serine glycine biosynthesis#P02776>Phosphoserine aminotransferase#P03157;Pyridoxal-5-phosphate biosynthesis#P02759>Phosphohydroxythreonine aminotransferase#P03058 LEPOC|Ensembl=ENSLOCG00000004688.1|UniProtKB=W5MB64 W5MB64 PTHR11731:SF97 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED INACTIVE DIPEPTIDYL PEPTIDASE 10 ISOFORM X1 catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238 regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;macromolecule metabolic process#GO:0043170;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of monoatomic cation transmembrane transport#GO:1904062;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of transmembrane transport#GO:0034762;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;proteolysis#GO:0006508 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 serine protease#PC00203;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000014866.1|UniProtKB=W5NCE9 W5NCE9 PTHR16134:SF1 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX AND LEUCINE-RICH PROTEIN 22 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 response to stimulus#GO:0050896;response to light stimulus#GO:0009416;catabolic process#GO:0009056;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;regulation of circadian rhythm#GO:0042752;response to radiation#GO:0009314;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;response to external stimulus#GO:0009605;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;photoperiodism#GO:0009648 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000001825.1|UniProtKB=W5M152 W5M152 PTHR12059:SF5 RIBOSOMAL PROTEIN L23-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL23M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000005924.1|UniProtKB=W5MFJ3 W5MFJ3 PTHR24201:SF2 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 42 transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000006678.1|UniProtKB=W5MI51 W5MI51 PTHR20902:SF0 41-2 PROTEIN ANTIGEN-RELATED TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;TRAPP complex#GO:0030008 LEPOC|Ensembl=ENSLOCG00000008904.1|UniProtKB=W5MR32 W5MR32 PTHR11309:SF46 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 5 signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;biological regulation#GO:0065007;signaling#GO:0023052;non-canonical Wnt signaling pathway#GO:0035567;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434 LEPOC|Ensembl=ENSLOCG00000008713.1|UniProtKB=W5MQE9 W5MQE9 PTHR10638:SF3 COPPER AMINE OXIDASE DIAMINE OXIDASE [COPPER-CONTAINING] oxidoreductase activity#GO:0016491;copper ion binding#GO:0005507;catalytic activity#GO:0003824;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;biogenic amine metabolic process#GO:0006576 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 oxidoreductase#PC00176;oxidase#PC00175 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 LEPOC|Ensembl=ENSLOCG00000015877.1|UniProtKB=W5NFZ3 W5NFZ3 PTHR45783:SF6 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 4 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 LEPOC|Ensembl=ENSLOCG00000015118.1|UniProtKB=W5ND95 W5ND95 PTHR15608:SF0 SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2 17S U2 SNRNP COMPLEX COMPONENT HTATSF1 RNA binding#GO:0003723;chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;nucleic acid binding#GO:0003676 protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;localization#GO:0051179;RNA splicing, via transesterification reactions#GO:0000375;protein localization to organelle#GO:0033365;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987 membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;site of double-strand break#GO:0035861;small nuclear ribonucleoprotein complex#GO:0030532;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000011162.1|UniProtKB=W5MZA9 W5MZA9 PTHR13256:SF16 N-ACETYLTRANSFERASE 9 ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 regulation of microtubule polymerization or depolymerization#GO:0031110;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular component biogenesis#GO:0044089;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of microtubule-based process#GO:0032886;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;regulation of microtubule polymerization#GO:0031113;regulation of protein-containing complex assembly#GO:0043254;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087 LEPOC|Ensembl=ENSLOCG00000008438.1|UniProtKB=W5MPF2 W5MPF2 PTHR12475:SF4 FAMILY NOT NAMED PROTEIN THEM6 LEPOC|Ensembl=ENSLOCG00000013942.1|UniProtKB=W5N980 W5N980 PTHR22883:SF207 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC2 catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;protein targeting to membrane#GO:0006612;developmental process#GO:0032502;protein targeting#GO:0006605;synapse assembly#GO:0007416;cell junction organization#GO:0034330;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;anatomical structure development#GO:0048856;cellular localization#GO:0051641;localization#GO:0051179;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;localization within membrane#GO:0051668 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000006538.1|UniProtKB=W5MHP0 W5MHP0 PTHR21191:SF7 AQUAPORIN AQUAPORIN-11 channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372 regulation of cell size#GO:0008361;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;regulation of anatomical structure size#GO:0090066;homeostatic process#GO:0042592;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000006470.1|UniProtKB=W5MHI4 W5MHI4 PTHR22624:SF39 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4B cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787 proteolysis#GO:0006508;organelle assembly#GO:0070925;protein metabolic process#GO:0019538;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;mitophagy#GO:0000423;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagy#GO:0006914;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;autophagosome organization#GO:1905037;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;macroautophagy#GO:0016236 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000009712.1|UniProtKB=W5MU03 W5MU03 PTHR45805:SF14 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-BETA sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C4 zinc finger nuclear receptor#PC00169 LEPOC|Ensembl=ENSLOCG00000011318.1|UniProtKB=W5MZV3 W5MZV3 PTHR14025:SF20 FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER FANCONI ANEMIA GROUP M PROTEIN ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;four-way junction DNA binding#GO:0000400;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000009552.1|UniProtKB=W5MTG8 W5MTG8 PTHR42961:SF4 IRON-SULFUR PROTEIN NUBPL IRON-SULFUR CLUSTER TRANSFER PROTEIN NUBPL binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 LEPOC|Ensembl=ENSLOCG00000014057.1|UniProtKB=W5N9M1 W5N9M1 PTHR11915:SF434 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-1 actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010 cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;intracellular organelle#GO:0043229;myofibril#GO:0030016;actin filament bundle#GO:0032432;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane#GO:0016020;actomyosin#GO:0042641;Z disc#GO:0030018;cell periphery#GO:0071944;contractile muscle fiber#GO:0043292;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;stress fiber#GO:0001725;cytoskeleton#GO:0005856;I band#GO:0031674;membraneless organelle#GO:0043228;sarcomere#GO:0030017;cell junction#GO:0030054 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 LEPOC|Ensembl=ENSLOCG00000015492.1|UniProtKB=W5NEL1 W5NEL1 PTHR11371:SF28 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1-LIKE 1 DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;DNA binding#GO:0003677;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787 nucleobase-containing compound catabolic process#GO:0034655;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 endodeoxyribonuclease#PC00093 LEPOC|Ensembl=ENSLOCG00000013090.1|UniProtKB=W5N666 W5N666 PTHR10285:SF143 URIDINE KINASE NICOTINAMIDE RIBOSIDE KINASE 2 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 nucleotide kinase#PC00172;kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000012162.1|UniProtKB=W5N2V3 W5N2V3 PTHR28556:SF6 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106A organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852 LEPOC|Ensembl=ENSLOCG00000010325.1|UniProtKB=W5MW93 W5MW93 PTHR24280:SF4 CYTOCHROME P450 20A1 CYTOCHROME P450 20A1 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000002227.1|UniProtKB=W5M2N0 W5M2N0 PTHR24006:SF925 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITINYL HYDROLASE 1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 cellular process#GO:0009987;regulation of protein stability#GO:0031647;cell migration#GO:0016477;cell motility#GO:0048870;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 protease#PC00190;cysteine protease#PC00081 LEPOC|Ensembl=ENSLOCG00000010723.1|UniProtKB=W5MXN5 W5MXN5 PTHR15751:SF13 TRAFFICKING KINESIN-BINDING PROTEIN TRAFFICKING KINESIN-BINDING PROTEIN 2 cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;signaling receptor binding#GO:0005102;binding#GO:0005488;GABA receptor binding#GO:0050811;protein binding#GO:0005515 nervous system development#GO:0007399;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;establishment of organelle localization#GO:0051656;protein targeting#GO:0006605;cell differentiation#GO:0030154;cellular localization#GO:0051641;animal gross anatomical part developmental process#GO:0160108;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;vesicle localization#GO:0051648;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;neurogenesis#GO:0022008;mitochondrion localization#GO:0051646;vesicle cytoskeletal trafficking#GO:0099518;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;anatomical structure development#GO:0048856;localization#GO:0051179;system development#GO:0048731;organelle localization#GO:0051640 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular vesicle#GO:0097708;mitochondrion#GO:0005739;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000605.1|UniProtKB=W5LX07 W5LX07 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000001301.1|UniProtKB=W5LZB9 W5LZB9 PTHR24391:SF11 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER E-BOX-BINDING HOMEOBOX 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000005895.1|UniProtKB=W5MFG3 W5MFG3 PTHR22911:SF138 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G1 export from cell#GO:0140352;metal ion transport#GO:0030001;homeostatic process#GO:0042592;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000006125.1|UniProtKB=W5MG97 W5MG97 PTHR23064:SF31 TROPONIN CALMODULIN LIKE 6 multicellular organismal process#GO:0032501;striated muscle contraction#GO:0006941;skeletal muscle contraction#GO:0003009;muscle system process#GO:0003012;system process#GO:0003008;muscle contraction#GO:0006936;neuromuscular process#GO:0050905;nervous system process#GO:0050877 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;myofibril#GO:0030016;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;contractile muscle fiber#GO:0043292;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;sarcomere#GO:0030017;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000006335.1|UniProtKB=W5MGZ3 W5MGZ3 PTHR15138:SF17 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4B DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 LEPOC|Ensembl=ENSLOCG00000016049.1|UniProtKB=W5NGL1 W5NGL1 PTHR11346:SF98 GALECTIN GALECTIN-RELATED PROTEIN carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000008597.1|UniProtKB=W5MPZ1 W5MPZ1 PTHR42757:SF46 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED NEURONAL GROWTH REGULATOR 1 regulation of cellular process#GO:0050794;regulation of synapse assembly#GO:0051963;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of synapse structure or activity#GO:0050803;regulation of biological quality#GO:0065008;regulation of synapse organization#GO:0050807;regulation of cell junction assembly#GO:1901888;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000013044.1|UniProtKB=W5N621 W5N621 PTHR21696:SF2 PROTEIN UNC-79 HOMOLOG PROTEIN UNC-79 HOMOLOG LEPOC|Ensembl=ENSLOCG00000011806.1|UniProtKB=W5N1L8 W5N1L8 PTHR23339:SF103 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE CYCLIN-DEPENDENT KINASE INHIBITOR 3 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000014363.1|UniProtKB=W5NAM4 W5NAM4 PTHR46839:SF3 SUSHI DOMAIN-CONTAINING PROTEIN 6 ZGC:152863 response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 LEPOC|Ensembl=ENSLOCG00000001399.1|UniProtKB=W5LZN4 W5LZN4 PTHR12157:SF25 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 3 structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 localization#GO:0051179;cell communication#GO:0007154;regulation of secretion#GO:0051046;secretion#GO:0046903;regulation of exocytosis#GO:0017157;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;regulation of neurotransmitter secretion#GO:0046928;export from cell#GO:0140352;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;regulation of transport#GO:0051049;exocytosis#GO:0006887;regulation of localization#GO:0032879;protein-containing complex organization#GO:0043933;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 presynaptic active zone#GO:0048786;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;synaptic membrane#GO:0097060;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;cell cortex#GO:0005938 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000011908.1|UniProtKB=W5N1Y7 W5N1Y7 PTHR22603:SF94 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137 LEPOC|Ensembl=ENSLOCG00000000098.1|UniProtKB=W5LVF0 W5LVF0 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000014359.1|UniProtKB=W5NAM1 W5NAM1 PTHR12125:SF1 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 50 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000001221.1|UniProtKB=W5LZ23 W5LZ23 PTHR19143:SF24 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 2 signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 LEPOC|Ensembl=ENSLOCG00000003011.1|UniProtKB=W5M5A4 W5M5A4 PTHR46654:SF1 E3 UBIQUITIN-PROTEIN LIGASE HECTD3 E3 UBIQUITIN-PROTEIN LIGASE HECTD3 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000010992.1|UniProtKB=W5MYN3 W5MYN3 PTHR45678:SF12 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED ELECTROGENIC ASPARTATE_GLUTAMATE ANTIPORTER SLC25A13, MITOCHONDRIAL carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 L-glutamate import#GO:0051938;pyridine-containing compound metabolic process#GO:0072524;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;primary metabolic process#GO:0044238;L-alpha-amino acid transmembrane transport#GO:1902475;nucleoside phosphate metabolic process#GO:0006753;carboxylic acid transmembrane transport#GO:1905039;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;establishment of localization#GO:0051234;NAD+ metabolic process#GO:0019674;aspartate transmembrane transport#GO:0015810;L-amino acid transport#GO:0015807;organophosphate metabolic process#GO:0019637;nitrogen compound transport#GO:0071705;nucleobase-containing compound metabolic process#GO:0006139;dicarboxylic acid transport#GO:0006835;nucleotide metabolic process#GO:0009117;transmembrane transport#GO:0055085;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;nucleobase-containing small molecule metabolic process#GO:0055086;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;L-glutamate transmembrane transport#GO:0015813 organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000005179.1|UniProtKB=W5MCZ5 W5MCZ5 PTHR10286:SF43 INORGANIC PYROPHOSPHATASE INORGANIC DIPHOSPHATASE pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 pyrophosphatase#PC00196 LEPOC|Ensembl=ENSLOCG00000003658.1|UniProtKB=W5M7I3 W5M7I3 PTHR11987:SF36 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-N-ACETYLNEURAMINATE ALPHA-2,8-SIALYLTRANSFERASE ST8SIA3 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;sialyltransferase activity#GO:0008373 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000016229.1|UniProtKB=W5NHA2 W5NHA2 PTHR19282:SF51 TETRASPANIN TETRASPANIN-32 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008952.1|UniProtKB=W5MR98 W5MR98 PTHR13906:SF6 PORCUPINE MEMBRANE-BOUND GLYCEROPHOSPHOLIPID O-ACYLTRANSFERASE 1 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid modification#GO:0030258 membrane#GO:0016020;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 LEPOC|Ensembl=ENSLOCG00000003541.1|UniProtKB=W5M729 W5M729 PTHR20966:SF2 ANKYRIN REPEAT AND SOCS BOX PROTEIN 17 ANKYRIN REPEAT AND SOCS BOX PROTEIN 17 proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 LEPOC|Ensembl=ENSLOCG00000008632.1|UniProtKB=W5MQ36 W5MQ36 PTHR10682:SF9 POLY A POLYMERASE POLY(A) POLYMERASE ALPHA transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000009269.1|UniProtKB=W5MSE6 W5MSE6 PTHR23055:SF80 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 3 molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000005870.1|UniProtKB=W5MFD1 W5MFD1 PTHR23162:SF8 OUTER DENSE FIBER OF SPERM TAILS 2 OUTER DENSE FIBER PROTEIN 2 regulation of organelle organization#GO:0033043;regulation of organelle assembly#GO:1902115;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cilium assembly#GO:1902017;regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell projection assembly#GO:0060491 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 LEPOC|Ensembl=ENSLOCG00000009988.1|UniProtKB=W5MV07 W5MV07 PTHR20930:SF10 OVARIAN CARCINOMA ANTIGEN CA125-RELATED PROTEIN ILRUN regulation of protein localization#GO:0032880;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;cellular localization#GO:0051641;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;regulation of localization#GO:0032879;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;establishment of protein localization#GO:0045184;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;protein targeting to vacuole#GO:0006623;regulation of multicellular organismal process#GO:0051239;protein localization to vacuole#GO:0072665;localization#GO:0051179;negative regulation of multicellular organismal process#GO:0051241;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;intracellular protein localization#GO:0008104;regulation of gene expression#GO:0010468;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cytokine production#GO:0001817;macromolecule localization#GO:0033036;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;macroautophagy#GO:0016236 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000010111.1|UniProtKB=W5MVG7 W5MVG7 PTHR13723:SF141 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 2 metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000008239.1|UniProtKB=W5MNP3 W5MNP3 PTHR22930:SF258 FAMILY NOT NAMED SUBFAMILY NOT NAMED LEPOC|Ensembl=ENSLOCG00000003337.1|UniProtKB=W5M6G9 W5M6G9 PTHR45761:SF4 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-3 metal ion binding#GO:0046872;cation binding#GO:0043169;lipid binding#GO:0008289;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;calcium ion binding#GO:0005509;phosphatidylcholine binding#GO:0031210;phospholipid binding#GO:0005543;phosphatidylinositol binding#GO:0035091 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007135.1|UniProtKB=W5MJS5 W5MJS5 PTHR24073:SF839 DRAB5-RELATED RAS-RELATED PROTEIN RAB-38 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 cell differentiation#GO:0030154;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;pigmentation#GO:0043473;developmental maturation#GO:0021700;cellular pigmentation#GO:0033059;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;developmental pigmentation#GO:0048066;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;response to external stimulus#GO:0009605;intracellular transport#GO:0046907;developmental process#GO:0032502;transport#GO:0006810;intracellular protein transport#GO:0006886 Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;melanosome#GO:0042470;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;mitochondrion#GO:0005739;vesicle#GO:0031982 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000005911.1|UniProtKB=W5MFI0 W5MFI0 PTHR43691:SF8 URIDINE PHOSPHORYLASE URIDINE PHOSPHORYLASE 2 glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;nucleobase-containing compound metabolic process#GO:0006139;nucleoside catabolic process#GO:0009164;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 LEPOC|Ensembl=ENSLOCG00000003601.1|UniProtKB=W5M7A8 W5M7A8 PTHR22306:SF2 CHROMOSOME 7 OPEN READING FRAME 50 PROTEIN CHOLESIN LEPOC|Ensembl=ENSLOCG00000017395.1|UniProtKB=W5NLJ1 W5NLJ1 PTHR24366:SF159 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS CARBOXYPEPTIDASE N SUBUNIT 2 immunoglobulin superfamily cell adhesion molecule#PC00125 LEPOC|Ensembl=ENSLOCG00000012266.1|UniProtKB=W5N383 W5N383 PTHR10454:SF206 CASPASE CASPASE-6 cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525;biological regulation#GO:0065007;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;regulation of neuron apoptotic process#GO:0043523 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 FAS signaling pathway#P00020>Caspase6#P00596;Huntington disease#P00029>Caspase 6#P00809;FAS signaling pathway#P00020>Pro-Caspase6#P00607 LEPOC|Ensembl=ENSLOCG00000002191.1|UniProtKB=W5M2E4 W5M2E4 PTHR10741:SF2 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000017192.1|UniProtKB=W5NKT8 W5NKT8 PTHR16517:SF1 TUBBY-RELATED WD REPEAT-CONTAINING PROTEIN 35 intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073 axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membraneless organelle#GO:0043228;intraciliary transport particle A#GO:0030991;cytoskeleton#GO:0005856;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000004382.1|UniProtKB=W5MA42 W5MA42 PTHR11373:SF48 DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;cellular process#GO:0009987;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;regulation of response to external stimulus#GO:0032101;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;defense response to virus#GO:0051607;phosphorus metabolic process#GO:0006793;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;regulation of response to stimulus#GO:0048583;nucleotide catabolic process#GO:0009166;regulation of response to stress#GO:0080134;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of innate immune response#GO:0045088;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;response to other organism#GO:0051707;regulation of immune response#GO:0050776;purine nucleotide catabolic process#GO:0006195;regulation of defense response#GO:0031347;organophosphate catabolic process#GO:0046434;response to virus#GO:0009615;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;response to external biotic stimulus#GO:0043207;nucleoside phosphate metabolic process#GO:0006753;regulation of response to biotic stimulus#GO:0002831;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;regulation of immune system process#GO:0002682;nucleoside phosphate catabolic process#GO:1901292 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000012232.1|UniProtKB=W5N339 W5N339 PTHR15591:SF19 RUN AND SH3 DOMAIN CONTAINING RUN DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000008340.1|UniProtKB=W5MP18 W5MP18 PTHR10969:SF54 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED ZGC:92606 binding#GO:0005488;signaling receptor binding#GO:0005102;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289;phospholipid binding#GO:0005543;GABA receptor binding#GO:0050811;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625 protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;cellular response to nutrient levels#GO:0031669;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;cellular response to starvation#GO:0009267 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;membrane#GO:0016020;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000015332.1|UniProtKB=W5NE14 W5NE14 PTHR10027:SF33 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1A-RELATED potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;calcium-activated cation channel activity#GO:0005227;potassium ion transmembrane transporter activity#GO:0015079;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic ion-gated channel activity#GO:0022839;calcium-activated potassium channel activity#GO:0015269;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000004045.1|UniProtKB=W5M934 W5M934 PTHR45838:SF2 HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER HISTONE-LYSINE N-METHYLTRANSFERASE 2A protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone H3K4 methyltransferase activity#GO:0042800;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993 positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000016899.1|UniProtKB=W5NJT0 W5NJT0 PTHR10510:SF15 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A3, MITOCHONDRIAL-RELATED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;respiratory chain complex#GO:0098803;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 oxidase#PC00175;oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000010564.1|UniProtKB=W5MX32 W5MX32 PTHR17097:SF0 NADH-UBIQUINONE OXIDOREDUCTASE KFYI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C1, MITOCHONDRIAL protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012262.1|UniProtKB=W5N377 W5N377 PTHR48482:SF3 INTERLEUKIN-19-RELATED INTERLEUKIN-19 cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000002744.1|UniProtKB=W5M4C4 W5M4C4 PTHR11950:SF43 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 3 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular process#GO:0009987;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;connective tissue development#GO:0061448;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;multicellular organismal process#GO:0032501;tissue development#GO:0009888;chondrocyte differentiation#GO:0002062;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;hemopoiesis#GO:0030097;biological regulation#GO:0065007;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cartilage development#GO:0051216;system development#GO:0048731;ossification#GO:0001503;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 Runt transcription factor#PC00254;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000012157.1|UniProtKB=W5N2V6 W5N2V6 PTHR45796:SF7 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P4 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 LEPOC|Ensembl=ENSLOCG00000011056.1|UniProtKB=W5MYW5 W5MYW5 PTHR11772:SF23 ASPARAGINE SYNTHETASE ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING] ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 proteinogenic amino acid biosynthetic process#GO:0170038;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ligase#PC00142 Asparagine and aspartate biosynthesis#P02730>Asparagine synthetase#P02853 LEPOC|Ensembl=ENSLOCG00000001942.1|UniProtKB=W5M1J5 W5M1J5 PTHR22747:SF28 NUCLEOPLASMIN NUCLEOPHOSMIN histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;protein binding#GO:0005515;RNA binding#GO:0003723 regulation of cell cycle process#GO:0010564;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;positive regulation of transcription by RNA polymerase II#GO:0045944;ribonucleoprotein complex biogenesis#GO:0022613;chromatin remodeling#GO:0006338;regulation of cell cycle#GO:0051726;establishment of organelle localization#GO:0051656;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular component organization#GO:0051128;ribosomal large subunit export from nucleus#GO:0000055;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cellular localization#GO:0051641;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;transport#GO:0006810;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;nuclear transport#GO:0051169;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;ribosome localization#GO:0033750;regulation of microtubule-based process#GO:0032886;organelle localization#GO:0051640 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000013920.1|UniProtKB=W5N951 W5N951 PTHR34651:SF1 SIMILAR TO ENSANGP00000021391 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 61 LEPOC|Ensembl=ENSLOCG00000003274.1|UniProtKB=W5M665 W5M665 PTHR23249:SF15 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;TRAPP complex#GO:0030008;protein-containing complex#GO:0032991 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000010104.1|UniProtKB=W5MVK7 W5MVK7 PTHR23345:SF9 VITELLOGENIN-RELATED VITELLOGENIN 2-RELATED molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 response to stimulus#GO:0050896;response to chemical#GO:0042221;response to lipid#GO:0033993;response to estradiol#GO:0032355;response to oxygen-containing compound#GO:1901700 storage protein#PC00210 LEPOC|Ensembl=ENSLOCG00000016383.1|UniProtKB=W5NHX4 W5NHX4 PTHR11003:SF138 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 3 monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836 monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 Dopamine receptor mediated signaling pathway#P05912>K+ channel#P05957;5HT3 type receptor mediated signaling pathway#P04375>K+ channel#P04425;5HT4 type receptor mediated signaling pathway#P04376>K+ channel#P04426;Opioid proenkephalin pathway#P05915>K+ channel#P05990;Nicotine pharmacodynamics pathway#P06587>KCNK3/9#P06605;5HT2 type receptor mediated signaling pathway#P04374>K+ channel#P04413;Opioid proopiomelanocortin pathway#P05917>K+ channel#P06009;5HT1 type receptor mediated signaling pathway#P04373>K+ channel#P04407 LEPOC|Ensembl=ENSLOCG00000008889.1|UniProtKB=W5MR12 W5MR12 PTHR13718:SF4 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000004004.1|UniProtKB=W5M8S4 W5M8S4 PTHR31230:SF1 MYELOID-DERIVED GROWTH FACTOR MYDGF MYELOID-DERIVED GROWTH FACTOR positive regulation of cell population proliferation#GO:0008284;positive regulation of angiogenesis#GO:0045766;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of cellular process#GO:0050794;positive regulation of epithelial cell proliferation#GO:0050679;regulation of developmental process#GO:0050793;regulation of cell population proliferation#GO:0042127;regulation of angiogenesis#GO:0045765;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of vasculature development#GO:1901342;positive regulation of developmental process#GO:0051094;regulation of anatomical structure morphogenesis#GO:0022603 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 LEPOC|Ensembl=ENSLOCG00000017006.1|UniProtKB=W5NK60 W5NK60 PTHR24356:SF453 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE LATS1 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of multicellular organismal process#GO:0051239;hippo signaling#GO:0035329;biological regulation#GO:0065007;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;mitotic cell cycle process#GO:1903047;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;G1/S transition of mitotic cell cycle#GO:0000082;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;cell cycle phase transition#GO:0044770;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of growth#GO:0040008;regulation of programmed cell death#GO:0043067;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;mitotic cell cycle phase transition#GO:0044772 non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000009026.1|UniProtKB=W5MRI9 W5MRI9 PTHR24073:SF941 DRAB5-RELATED RAS-RELATED PROTEIN RAB-20 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytosis#GO:0006897;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000001137.1|UniProtKB=W5LYS1 W5LYS1 PTHR11610:SF111 LIPASE PHOSPHOLIPASE A1 MEMBER A glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 2-arachidonoylglycerol biosynthesis#P05726>PLA1#P05735 LEPOC|Ensembl=ENSLOCG00000015428.1|UniProtKB=W5NEC5 W5NEC5 PTHR20859:SF87 INTERFERON/INTERLEUKIN RECEPTOR GROWTH_DIFFERENTIATION FACTOR 10B PRECURSOR-RELATED signaling receptor activity#GO:0038023;immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;cytokine receptor activity#GO:0004896 cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000006707.1|UniProtKB=W5MI92 W5MI92 PTHR10658:SF78 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN N-TERMINAL DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;intramembrane lipid carrier activity#GO:0140303;ion binding#GO:0043167;lipid carrier activity#GO:0005319;phosphatidylcholine intramembrane carrier activity#GO:0008525;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol transfer activity#GO:0008526;phosphatidylcholine binding#GO:0031210;phospholipid binding#GO:0005543;phosphatidylinositol binding#GO:0035091;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;binding#GO:0005488;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017370.1|UniProtKB=W5NLG6 W5NLG6 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000005123.1|UniProtKB=W5MCQ8 W5MCQ8 PTHR12669:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 2 translation regulator activity#GO:0045182;translation initiation factor binding#GO:0031369;protein binding#GO:0005515;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of synaptic plasticity#GO:0048167;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of trans-synaptic signaling#GO:0099177;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological quality#GO:0065008;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;regulation of signaling#GO:0023051;modulation of chemical synaptic transmission#GO:0050804;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629 translation initiation factor#PC00224;translation factor#PC00223 LEPOC|Ensembl=ENSLOCG00000018330.1|UniProtKB=W5NP72 W5NP72 PTHR35154:SF3 GBP PROTEIN GBP PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000016119.1|UniProtKB=W5NGV4 W5NGV4 PTHR20946:SF0 SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION lymphocyte activation involved in immune response#GO:0002285;cellular process#GO:0009987;somatic recombination of immunoglobulin gene segments#GO:0016447;lymphocyte activation#GO:0046649;gene expression#GO:0010467;DNA recombination#GO:0006310;immune effector process#GO:0002252;leukocyte activation involved in immune response#GO:0002366;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;B cell activation#GO:0042113;multicellular organism development#GO:0007275;response to stimulus#GO:0050896;production of molecular mediator of immune response#GO:0002440;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;immune system process#GO:0002376;B cell activation involved in immune response#GO:0002312;animal gross anatomical part developmental process#GO:0160108;immunoglobulin mediated immune response#GO:0016064;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cell activation involved in immune response#GO:0002263;immune system development#GO:0002520;leukocyte mediated immunity#GO:0002443;lymphocyte mediated immunity#GO:0002449;immune response#GO:0006955;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;adaptive immune response#GO:0002250;somatic cell DNA recombination#GO:0016444;multicellular organismal process#GO:0032501;developmental process#GO:0032502;macromolecule metabolic process#GO:0043170;somatic diversification of immune receptors#GO:0002200;leukocyte activation#GO:0045321;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell activation#GO:0001775;system development#GO:0048731;anatomical structure development#GO:0048856 LEPOC|Ensembl=ENSLOCG00000010584.1|UniProtKB=W5MX80 W5MX80 PTHR24038:SF8 STABILIN STABILIN-1 membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000007062.1|UniProtKB=W5MJJ0 W5MJJ0 COPS9 PTHR28562:SF1 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 LEPOC|Ensembl=ENSLOCG00000012481.1|UniProtKB=W5N405 W5N405 PTHR12872:SF5 ALPHA-N-ACETYLGLUCOSAMINIDASE ALPHA-N-ACETYLGLUCOSAMINIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000010661.1|UniProtKB=W5MXF7 W5MXF7 PTHR10459:SF66 DNA LIGASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP3 NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238 intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;site of double-strand break#GO:0035861;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;chromosome#GO:0005694;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 LEPOC|Ensembl=ENSLOCG00000016282.1|UniProtKB=W5NHH9 W5NHH9 TSHR PTHR24372:SF1 GLYCOPROTEIN HORMONE RECEPTOR LUTROPIN-CHORIOGONADOTROPIC HORMONE RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 cellular process#GO:0009987;sex differentiation#GO:0007548;signal transduction#GO:0007165;male gonad development#GO:0008584;response to hormone#GO:0009725;response to chemical#GO:0042221;development of primary sexual characteristics#GO:0045137;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;reproductive structure development#GO:0048608;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;rhythmic process#GO:0048511;animal gross anatomical part developmental process#GO:0160108;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;gonad development#GO:0008406;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;male sex differentiation#GO:0046661;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;developmental process#GO:0032502;development of primary male sexual characteristics#GO:0046546;cellular response to stimulus#GO:0051716;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;reproductive system development#GO:0061458;multicellular organismal reproductive process#GO:0048609;female gonad development#GO:0008585;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000005996.1|UniProtKB=W5MFT9 W5MFT9 PTHR26451:SF886 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED transmembrane signaling receptor activity#GO:0004888;olfactory receptor activity#GO:0004984;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 system process#GO:0003008;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907;sensory perception#GO:0007600;nervous system process#GO:0050877;response to chemical#GO:0042221;response to stimulus#GO:0050896;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of stimulus involved in sensory perception#GO:0050906;detection of stimulus#GO:0051606;detection of chemical stimulus#GO:0009593 cellular anatomical structure#GO:0110165;membrane#GO:0016020 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000002553.1|UniProtKB=W5M3Q4 W5M3Q4 PTHR20991:SF0 PARATHYROID HORMONE-RESPONSIVE B1 GENE PROTEIN PTHB1 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 cilium#GO:0005929;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;BBSome#GO:0034464;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 LEPOC|Ensembl=ENSLOCG00000003226.1|UniProtKB=W5M613 W5M613 PTHR15830:SF10 TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG heat shock protein binding#GO:0031072;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;Hsp90 protein binding#GO:0051879;binding#GO:0005488;nucleic acid binding#GO:0003676;protein binding#GO:0005515;DNA binding#GO:0003677 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 LEPOC|Ensembl=ENSLOCG00000007132.1|UniProtKB=W5MJS4 W5MJS4 COQ7 PTHR11237:SF6 COENZYME Q10 BIOSYNTHESIS PROTEIN 7 NADPH-DEPENDENT 3-DEMETHOXYUBIQUINONE 3-HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824 regulation of metabolic process#GO:0019222;ketone metabolic process#GO:0042180;regulation of biological process#GO:0050789;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;small molecule metabolic process#GO:0044281;multicellular organismal process#GO:0032501;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;regulation of reactive oxygen species metabolic process#GO:2000377;small molecule biosynthetic process#GO:0044283 cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000008281.1|UniProtKB=W5MNU9 W5MNU9 PTHR23113:SF220 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 3 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000010345.1|UniProtKB=W5MWC1 W5MWC1 PTHR16056:SF16 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 1 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 intracellular organelle#GO:0043229;microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spindle pole#GO:0000922;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;spindle#GO:0005819;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 LEPOC|Ensembl=ENSLOCG00000003315.1|UniProtKB=W5M6B0 W5M6B0 PTHR28457:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 119 LEPOC|Ensembl=ENSLOCG00000017643.1|UniProtKB=W5NM89 W5NM89 PTHR22750:SF16 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 1 bioactive lipid receptor activity#GO:0045125;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 biological regulation#GO:0065007;tube development#GO:0035295;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;vasculature development#GO:0001944;anatomical structure formation involved in morphogenesis#GO:0048646;multicellular organism development#GO:0007275;developmental process#GO:0032502;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signaling#GO:0023052;response to stimulus#GO:0050896;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;blood vessel development#GO:0001568;tube morphogenesis#GO:0035239;blood vessel morphogenesis#GO:0048514;system development#GO:0048731;cell communication#GO:0007154;angiogenesis#GO:0001525;anatomical structure development#GO:0048856;G protein-coupled receptor signaling pathway#GO:0007186;animal gross anatomical part developmental process#GO:0160108 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003200.1|UniProtKB=W5M5X1 W5M5X1 PTHR12498:SF0 N-TERMINAL ASPARAGINE AMIDOHYDROLASE PROTEIN N-TERMINAL ASPARAGINE AMIDOHYDROLASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000003808.1|UniProtKB=W5M832 W5M832 PTHR11818:SF129 BETA/GAMMA CRYSTALLIN CRYSTALLIN, GAMMA M6-RELATED structural molecule activity#GO:0005198 lens development in camera-type eye#GO:0002088;developmental process#GO:0032502;sensory organ development#GO:0007423;system process#GO:0003008;multicellular organism development#GO:0007275;animal organ development#GO:0048513;sensory system development#GO:0048880;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;camera-type eye development#GO:0043010;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;eye development#GO:0001654;anatomical structure development#GO:0048856;sensory perception of light stimulus#GO:0050953;visual system development#GO:0150063;visual perception#GO:0007601 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010428.1|UniProtKB=W5MWP0 W5MWP0 PTHR19134:SF468 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE GAMMA phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275 protein phosphatase#PC00195;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008198.1|UniProtKB=W5MNJ5 W5MNJ5 PTHR12743:SF0 CYTOCHROME C1 HEME LYASE HOLOCYTOCHROME C-TYPE SYNTHASE catalytic activity#GO:0003824;lyase activity#GO:0016829;catalytic activity, acting on a protein#GO:0140096;carbon-sulfur lyase activity#GO:0016846 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 lyase#PC00144 LEPOC|Ensembl=ENSLOCG00000000112.1|UniProtKB=W5LVG9 W5LVG9 PTHR48034:SF5 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED COLD-INDUCIBLE RNA-BINDING PROTEIN RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000005696.1|UniProtKB=W5MER7 W5MER7 PTHR15692:SF9 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;Notch signaling pathway#GO:0007219;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000009165.1|UniProtKB=W5MS27 W5MS27 PTHR14445:SF38 GRB10 INTERACTING GYF PROTEIN GRB10-INTERACTING GYF PROTEIN 2 translation regulator activity#GO:0045182 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule metabolic process#GO:0010605;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;insulin-like growth factor receptor signaling pathway#GO:0048009;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell surface receptor signaling pathway#GO:0007166;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;cell body#GO:0044297;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;dendrite#GO:0030425;dendritic tree#GO:0097447;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cytosol#GO:0005829;neuron projection#GO:0043005;perikaryon#GO:0043204 LEPOC|Ensembl=ENSLOCG00000014319.1|UniProtKB=W5NAH1 W5NAH1 PTHR12352:SF32 SECRETED MODULAR CALCIUM-BINDING PROTEIN THYROGLOBULIN TYPE-1 DOMAIN-CONTAINING PROTEIN heparin binding#GO:0008201;binding#GO:0005488;glycosaminoglycan binding#GO:0005539;carbohydrate derivative binding#GO:0097367;extracellular matrix binding#GO:0050840 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000009615.1|UniProtKB=W5MTP7 W5MTP7 PTHR23406:SF20 MALIC ENZYME-RELATED NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000011397.1|UniProtKB=W5N056 W5N056 PTHR10589:SF24 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L3 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005565.1|UniProtKB=W5MEB1 W5MEB1 PTHR15742:SF1 GIRDIN MICROTUBULE CROSS-LINKING FACTOR 2 microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000001195.1|UniProtKB=W5LZ01 W5LZ01 PTHR10465:SF2 TRANSMEMBRANE GTPASE FZO1 MITOFUSIN-1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 mitochondrion localization#GO:0051646;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organelle localization#GO:0051640;mitochondrion organization#GO:0007005;organelle fusion#GO:0048284;cellular process#GO:0009987;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular component organization#GO:0016043 membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000004015.1|UniProtKB=W5M8V4 W5M8V4 PTHR43108:SF4 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan metabolic process#GO:0006029;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of macromolecule metabolic process#GO:0010604;regulation of multicellular organismal process#GO:0051239;negative regulation of signal transduction#GO:0009968;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;carbohydrate derivative metabolic process#GO:1901135;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;positive regulation of cell communication#GO:0010647;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;carbohydrate derivative catabolic process#GO:1901136;regulation of cell communication#GO:0010646 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000009044.1|UniProtKB=W5MRM0 W5MRM0 PTHR13196:SF25 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1C phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000012184.1|UniProtKB=W5N2Y6 W5N2Y6 PTHR10887:SF5 DNA2/NAM7 HELICASE FAMILY RNA HELICASE AQUARIUS RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 RNA helicase#PC00032 LEPOC|Ensembl=ENSLOCG00000008315.1|UniProtKB=W5MNZ2 W5MNZ2 PTHR28658:SF1 TRANSMEMBRANE PROTEIN 180 MAJOR FACILITATOR SUPERFAMILY DOMAIN CONTAINING 13B LEPOC|Ensembl=ENSLOCG00000013970.1|UniProtKB=W5N9B2 W5N9B2 PTHR11224:SF17 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-2 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000008406.1|UniProtKB=W5MPA8 W5MPA8 PTHR11243:SF22 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;cellular response to peptide hormone stimulus#GO:0071375;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to hormone#GO:0009725;negative regulation of signal transduction#GO:0009968;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;negative regulation of signaling#GO:0023057;cellular response to chemical stimulus#GO:0070887;negative regulation of cell communication#GO:0010648 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Grb14#P00197 LEPOC|Ensembl=ENSLOCG00000007095.1|UniProtKB=W5MJN2 W5MJN2 PTHR31462:SF5 ENDOSOMAL/LYSOSOMAL POTASSIUM CHANNEL TMEM175 ENDOSOMAL_LYSOSOMAL PROTON CHANNEL TMEM175 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000013911.1|UniProtKB=W5N939 W5N939 PTHR34605:SF3 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN MUCIN-2-LIKE ISOFORM X1 LEPOC|Ensembl=ENSLOCG00000012720.1|UniProtKB=W5N4V2 W5N4V2 PTHR10663:SF340 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-1 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000008730.1|UniProtKB=W5MQG6 W5MQG6 PTHR48071:SF37 SRCR DOMAIN-CONTAINING PROTEIN SRCR DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000013867.1|UniProtKB=W5N8Z8 W5N8Z8 PTHR19431:SF0 60S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 translational protein#PC00263;ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000012147.1|UniProtKB=W5N2U1 W5N2U1 PTHR18934:SF277 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX8 catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000008672.1|UniProtKB=W5MQ96 W5MQ96 PTHR24025:SF22 DESMOGLEIN FAMILY MEMBER PROTOCADHERIN-16 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 cadherin#PC00057 LEPOC|Ensembl=ENSLOCG00000001981.1|UniProtKB=W5M1N6 W5M1N6 PTHR22804:SF10 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 1 developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;skeletal system development#GO:0001501;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417 cell junction#GO:0030054;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;cell periphery#GO:0071944 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 LEPOC|Ensembl=ENSLOCG00000013149.1|UniProtKB=W5N6D7 W5N6D7 MED11 PTHR22890:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015179.1|UniProtKB=W5NDG9 W5NDG9 PTHR45806:SF1 SYNAPTOBREVIN HOMOLOG YKT6 SYNAPTOBREVIN HOMOLOG YKT6 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 vacuole fusion#GO:0097576;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization#GO:0016043;intra-Golgi vesicle-mediated transport#GO:0006891;catabolic process#GO:0009056;vesicle fusion#GO:0006906;metabolic process#GO:0008152;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987;autophagy#GO:0006914;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;vacuole fusion, non-autophagic#GO:0042144;organelle membrane fusion#GO:0090174;macroautophagy#GO:0016236;membrane organization#GO:0061024 membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;organelle#GO:0043226;intracellular organelle#GO:0043229;autophagosome#GO:0005776;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000006095.1|UniProtKB=W5MG52 W5MG52 PTHR10083:SF328 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED TISSUE FACTOR PATHWAY INHIBITOR peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 Blood coagulation#P00011>TFPI#P00417 LEPOC|Ensembl=ENSLOCG00000008991.1|UniProtKB=W5MRE4 W5MRE4 PTHR23250:SF3 DYSFERLIN-RELATED FISH-EGG LECTIN-LIKE ISOFORM X1-RELATED LEPOC|Ensembl=ENSLOCG00000000665.1|UniProtKB=W5LX78 W5LX78 PTHR21014:SF2 PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE TYPE 1 PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 4-PHOSPHATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;dephosphorylation#GO:0016311;lipid modification#GO:0030258 lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;phagocytic vesicle#GO:0045335;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000010303.1|UniProtKB=W5MW76 W5MW76 PTHR10653:SF5 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-1 binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835;regulation of actin filament length#GO:0030832;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;actin filament-based process#GO:0030029;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of protein depolymerization#GO:1901879;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell periphery#GO:0071944;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 non-motor actin binding protein#PC00165 LEPOC|Ensembl=ENSLOCG00000006110.1|UniProtKB=W5MG78 W5MG78 PTHR10414:SF35 ETHANOLAMINEPHOSPHOTRANSFERASE ETHANOLAMINEPHOSPHOTRANSFERASE 1 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000013780.1|UniProtKB=W5N8P0 W5N8P0 PTHR22775:SF48 SORTING NEXIN SORTING NEXIN-25 phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000001328.1|UniProtKB=W5LZF3 W5LZF3 PTHR14187:SF39 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12B LEPOC|Ensembl=ENSLOCG00000011884.1|UniProtKB=W5N1V0 W5N1V0 PTHR46171:SF2 GH10160P RING FINGER PROTEIN 44 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 LEPOC|Ensembl=ENSLOCG00000002798.1|UniProtKB=W5M4J2 W5M4J2 PTHR12755:SF3 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9 phosphotransferase activity, alcohol group as acceptor#GO:0016773;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147 LEPOC|Ensembl=ENSLOCG00000002280.1|UniProtKB=W5M2R0 W5M2R0 PTHR48021:SF18 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 8 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carbohydrate transport#GO:0008643;transport#GO:0006810;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000006741.1|UniProtKB=W5MID0 W5MID0 PTHR31305:SF3 SNARE-ASSOCIATED PROTEIN SNAPIN SNARE-ASSOCIATED PROTEIN SNAPIN binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515 lysosomal transport#GO:0007041;secretion by cell#GO:0032940;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;regulation of biological process#GO:0050789;intracellular monoatomic ion homeostasis#GO:0006873;export from cell#GO:0140352;signaling#GO:0023052;establishment of organelle localization#GO:0051656;chemical homeostasis#GO:0048878;regulated exocytosis#GO:0045055;endosomal transport#GO:0016197;exocytosis#GO:0006887;vesicle-mediated transport in synapse#GO:0099003;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;synaptic signaling#GO:0099536;synaptic vesicle transport#GO:0048489;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;regulation of intracellular pH#GO:0051453;signal release#GO:0023061;organelle localization#GO:0051640;regulation of pH#GO:0006885;trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;homeostatic process#GO:0042592;anterograde trans-synaptic signaling#GO:0098916;vacuolar transport#GO:0007034;synaptic vesicle cycle#GO:0099504;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular transport#GO:0046907;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;vesicle localization#GO:0051648;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269 secretory vesicle#GO:0099503;presynapse#GO:0098793;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle#GO:0030133;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular protein-containing complex#GO:0140535;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;BLOC-1 complex#GO:0031083 LEPOC|Ensembl=ENSLOCG00000011594.1|UniProtKB=W5N0V5 W5N0V5 PTHR45999:SF3 UNC-13-4A, ISOFORM B PROTEIN UNC-13 HOMOLOG D transport#GO:0006810;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234 transport vesicle#GO:0030133;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 Synaptic vesicle trafficking#P05734>Munc13#P05773 LEPOC|Ensembl=ENSLOCG00000003977.1|UniProtKB=W5M8P5 W5M8P5 PTHR45819:SF3 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function activator activity#GO:0140677;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589 regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;negative regulation of neuron apoptotic process#GO:0043524;negative regulation of biological process#GO:0048519;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 nucleus#GO:0005634;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 GTPase-activating protein#PC00257;G-protein modulator#PC00022 LEPOC|Ensembl=ENSLOCG00000006353.1|UniProtKB=W5MH09 W5MH09 PTHR11461:SF20 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-2-ANTIPLASMIN peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240;positive regulation of coagulation#GO:0050820;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of coagulation#GO:0050818 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Plasminogen activating cascade#P00050>alpha2 antiplasmin#P01264;Blood coagulation#P00011>alpha2-antiplasmin#P00428 LEPOC|Ensembl=ENSLOCG00000001133.1|UniProtKB=W5LYR9 W5LYR9 PTHR45828:SF44 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 LEPOC|Ensembl=ENSLOCG00000013291.1|UniProtKB=W5N6Y8 W5N6Y8 PTHR22762:SF60 ALPHA-GLUCOSIDASE NEUTRAL ALPHA-GLUCOSIDASE C glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;alpha-glucosidase activity#GO:0090599 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 glucosidase#PC00108 LEPOC|Ensembl=ENSLOCG00000007775.1|UniProtKB=W5MM33 W5MM33 PTHR12757:SF4 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 2 regulation of T cell activation#GO:0050863;regulation of response to external stimulus#GO:0032101;negative regulation of cell-cell adhesion#GO:0022408;negative regulation of leukocyte activation#GO:0002695;negative regulation of lymphocyte activation#GO:0051250;regulation of multicellular organismal process#GO:0051239;negative regulation of response to external stimulus#GO:0032102;regulation of lymphocyte activation#GO:0051249;negative regulation of biological process#GO:0048519;regulation of leukocyte activation#GO:0002694;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of cell adhesion#GO:0030155;negative regulation of cell adhesion#GO:0007162;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of cell activation#GO:0050866;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of response to stimulus#GO:0048583;regulation of cell-cell adhesion#GO:0022407;negative regulation of inflammatory response#GO:0050728;regulation of cellular process#GO:0050794;negative regulation of defense response#GO:0031348;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;negative regulation of leukocyte cell-cell adhesion#GO:1903038;negative regulation of multicellular organismal process#GO:0051241;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;negative regulation of T cell activation#GO:0050868 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000014445.1|UniProtKB=W5NAX0 W5NAX0 PTHR11581:SF0 30S/40S RIBOSOMAL PROTEIN S4 RIBOSOMAL PROTEIN S4 Y1-RELATED structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 LEPOC|Ensembl=ENSLOCG00000014825.1|UniProtKB=W5NC96 W5NC96 PTHR10366:SF860 NAD DEPENDENT EPIMERASE/DEHYDRATASE STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;secondary alcohol metabolic process#GO:1902652;steroid metabolic process#GO:0008202;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 dehydratase#PC00091;lyase#PC00144;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000009760.1|UniProtKB=W5MU98 W5MU98 PTHR12517:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13B membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000013754.1|UniProtKB=W5N8N5 W5N8N5 PTHR22625:SF35 PLEXIN PLEXIN-A1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane bounded cell projection organization#GO:0120036;negative regulation of cell adhesion#GO:0007162;cellular developmental process#GO:0048869;developmental process#GO:0032502;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;system development#GO:0048731;regulation of nervous system development#GO:0051960;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;regulation of axonogenesis#GO:0050770;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;positive regulation of axonogenesis#GO:0050772;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;regulation of plasma membrane bounded cell projection organization#GO:0120035;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;anatomical structure development#GO:0048856;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;positive regulation of cell development#GO:0010720;nervous system development#GO:0007399;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of cell differentiation#GO:0045597;neuron differentiation#GO:0030182;cell development#GO:0048468;cell morphogenesis#GO:0000902;synapse assembly#GO:0007416;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cell shape#GO:0008360;positive regulation of multicellular organismal process#GO:0051240;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;regulation of biological quality#GO:0065008;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Axon guidance mediated by semaphorins#P00007>PlexinA1#P00334 LEPOC|Ensembl=ENSLOCG00000005892.1|UniProtKB=W5MFF9 W5MFF9 PTHR21549:SF1 MUTATED IN BLADDER CANCER 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 148 LEPOC|Ensembl=ENSLOCG00000014908.1|UniProtKB=W5NCK2 W5NCK2 PTHR11036:SF80 SEMAPHORIN SEMAPHORIN-7A binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;integrin binding#GO:0005178 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;response to chemical#GO:0042221;taxis#GO:0042330;regulation of response to external stimulus#GO:0032101;chemotaxis#GO:0006935;regulation of defense response#GO:0031347;regulation of inflammatory response#GO:0050727;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;locomotion#GO:0040011;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of response to stimulus#GO:0048583;neuron projection morphogenesis#GO:0048812;regulation of response to stress#GO:0080134;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501 cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000014782.1|UniProtKB=W5NC48 W5NC48 PTHR48015:SF12 SERINE/THREONINE-PROTEIN KINASE TAO NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000022.1|UniProtKB=W5LV67 W5LV67 PTHR11360:SF318 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 12 monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000010096.1|UniProtKB=W5MVE3 W5MVE3 PTHR10755:SF0 COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;cellular process#GO:0009987;porphyrin-containing compound biosynthetic process#GO:0006779;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;oxidase#PC00175;metabolite interconversion enzyme#PC00262 Heme biosynthesis#P02746>Coproporphyrinogen Oxidase (oxygen dependent)#P02980 LEPOC|Ensembl=ENSLOCG00000017761.1|UniProtKB=W5NMK6 W5NMK6 PTHR24070:SF290 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE, FAMILY 10, MEMBER A ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017388.1|UniProtKB=W5NLI4 W5NLI4 RNF228 PTHR22791:SF17 RING-TYPE DOMAIN-CONTAINING PROTEIN RING FINGER PROTEIN 228 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 ubiquitin-protein ligase#PC00234 LEPOC|Ensembl=ENSLOCG00000015774.1|UniProtKB=W5NFL1 W5NFL1 PTHR18934:SF145 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX57-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853 RNA helicase#PC00032;RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000011570.1|UniProtKB=W5N0R0 W5N0R0 PTHR24103:SF667 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM69 ISOFORM X1 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to biotic stimulus#GO:0009607;response to stress#GO:0006950 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000011896.1|UniProtKB=W5N1X1 W5N1X1 PTHR15021:SF2 DISCONNECTED-RELATED ZINC FINGER PROTEIN BASONUCLIN-2 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000016104.1|UniProtKB=W5NGT2 W5NGT2 PTHR15186:SF3 RE48077P BCL2_ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3-LIKE process utilizing autophagic mechanism#GO:0061919;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;cellular component organization#GO:0016043;regulation of programmed cell death#GO:0043067;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;mitophagy#GO:0000423;regulation of apoptotic process#GO:0042981;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;apoptotic mitochondrial changes#GO:0008637;macroautophagy#GO:0016236;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;autophagy#GO:0006914;positive regulation of cellular process#GO:0048522;organelle organization#GO:0006996 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;endoplasmic reticulum#GO:0005783;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967 LEPOC|Ensembl=ENSLOCG00000002181.1|UniProtKB=W5M2E7 W5M2E7 PTHR11521:SF32 TROPONIN T TROPONIN T TYPE 3B (SKELETAL, FAST) ISOFORM X1 cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 multicellular organismal process#GO:0032501;cellular developmental process#GO:0048869;system process#GO:0003008;developmental process#GO:0032502;muscle contraction#GO:0006936;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108 contractile muscle fiber#GO:0043292;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;sarcomere#GO:0030017;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016 actin binding motor protein#PC00040 LEPOC|Ensembl=ENSLOCG00000003234.1|UniProtKB=W5M626 W5M626 PTHR31198:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 84 CENTROSOMAL AT-AC SPLICING FACTOR LEPOC|Ensembl=ENSLOCG00000001460.1|UniProtKB=W5LZY2 W5LZY2 PTHR24211:SF15 LIM DOMAIN-CONTAINING PROTEIN PRICKLE-LIKE PROTEIN 1 embryo development#GO:0009790;nervous system development#GO:0007399;neuron projection development#GO:0031175;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;embryonic morphogenesis#GO:0048598;anatomical structure formation involved in morphogenesis#GO:0048646;morphogenesis of an epithelium#GO:0002009;neuron differentiation#GO:0030182;intracellular protein transport#GO:0006886;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular localization#GO:0051641;protein import into nucleus#GO:0006606;neuron development#GO:0048666;protein transport#GO:0015031;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;generation of neurons#GO:0048699;epithelium development#GO:0060429;cell migration#GO:0016477;multicellular organismal process#GO:0032501;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;tube development#GO:0035295;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization to organelle#GO:0072594;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;neurogenesis#GO:0022008;intracellular transport#GO:0046907;developmental process#GO:0032502;transport#GO:0006810;cell motility#GO:0048870;protein localization to organelle#GO:0033365;establishment of cell polarity#GO:0030010;tube morphogenesis#GO:0035239;tissue morphogenesis#GO:0048729;localization#GO:0051179;anatomical structure development#GO:0048856;nuclear transport#GO:0051169;system development#GO:0048731;embryo development ending in birth or egg hatching#GO:0009792;nucleocytoplasmic transport#GO:0006913 neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;intracellular membrane-bounded organelle#GO:0043231;postsynapse#GO:0098794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;postsynaptic density#GO:0014069;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002417.1|UniProtKB=W5M396 W5M396 PTHR11036:SF39 SEMAPHORIN SEMAPHORIN-5B protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 cell surface receptor signaling pathway#GO:0007166;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell growth#GO:0016049;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;axon extension#GO:0048675;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;axonogenesis#GO:0007409;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;neuron projection extension#GO:1990138;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;developmental growth#GO:0048589;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;positive regulation of locomotion#GO:0040017;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;developmental cell growth#GO:0048588 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000012244.1|UniProtKB=W5N348 W5N348 PTHR19308:SF59 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN PHOSPHATIDYLCHOLINE TRANSFER PROTEIN phosphatidylcholine binding#GO:0031210;transporter activity#GO:0005215;phospholipid binding#GO:0005543;cation binding#GO:0043169;lipid binding#GO:0008289;intramembrane lipid carrier activity#GO:0140303;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylcholine intramembrane carrier activity#GO:0008525;ion binding#GO:0043167;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 LEPOC|Ensembl=ENSLOCG00000012040.1|UniProtKB=W5N2F1 W5N2F1 PTHR14557:SF4 PROTEIN C7ORF21 TRANSMEMBRANE AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN 2 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896 LEPOC|Ensembl=ENSLOCG00000014681.1|UniProtKB=W5NBR4 W5NBR4 PTHR46527:SF2 NUCLEOPORIN-LIKE PROTEIN 2 NUCLEOPORIN NUP42 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000001719.1|UniProtKB=W5M0S3 W5M0S3 CTU1 PTHR11807:SF12 ATPASES OF THE PP SUPERFAMILY-RELATED CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA wobble position uridine thiolation#GO:0002143;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;tRNA thio-modification#GO:0034227 sulfurtransferase complex#GO:1990228;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000005827.1|UniProtKB=W5MF77 W5MF77 PTHR28676:SF1 ALK AND LTK LIGAND 2-RELATED ALK AND LTK LIGAND 1 kinase activator activity#GO:0019209;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;molecular function regulator activity#GO:0098772;receptor tyrosine kinase binding#GO:0030971;protein kinase activator activity#GO:0030295;molecular function activator activity#GO:0140677;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047 positive regulation of response to stimulus#GO:0048584;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of MAPK cascade#GO:0043410;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 LEPOC|Ensembl=ENSLOCG00000007540.1|UniProtKB=W5MLB6 W5MLB6 PTHR24255:SF25 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1R SUBCOMPONENT serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;zymogen activation#GO:0031638;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 LEPOC|Ensembl=ENSLOCG00000003348.1|UniProtKB=W5M6E5 W5M6E5 PTHR22768:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF3 DNA REPLICATION COMPLEX GINS PROTEIN PSF3 DNA replication#GO:0006260;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-DNA complex#GO:0032993;organelle#GO:0043226;nucleoplasm#GO:0005654;DNA replication preinitiation complex#GO:0031261;chromosome#GO:0005694;organelle lumen#GO:0043233 LEPOC|Ensembl=ENSLOCG00000005783.1|UniProtKB=W5MF26 W5MF26 PTHR10408:SF10 STEROL O-ACYLTRANSFERASE STEROL O-ACYLTRANSFERASE 2 steroid binding#GO:0005496;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;alcohol binding#GO:0043178;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;transferase activity#GO:0016740;cholesterol binding#GO:0015485;lipid binding#GO:0008289;acyltransferase activity#GO:0016746;nucleoside phosphate binding#GO:1901265;sterol binding#GO:0032934;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 lipid localization#GO:0010876;organic hydroxy compound transport#GO:0015850;localization#GO:0051179;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;transport#GO:0006810;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;establishment of localization#GO:0051234;sterol metabolic process#GO:0016125;sterol transport#GO:0015918;cholesterol efflux#GO:0033344;cellular process#GO:0009987;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;steroid metabolic process#GO:0008202;lipid transport#GO:0006869 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 LEPOC|Ensembl=ENSLOCG00000004514.1|UniProtKB=W5MAK7 W5MAK7 PTHR10926:SF19 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50B enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000003178.1|UniProtKB=W5M5U5 W5M5U5 PTHR23274:SF51 DNA HELICASE-RELATED ATP-DEPENDENT DNA HELICASE ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 DNA helicase#PC00011 LEPOC|Ensembl=ENSLOCG00000007211.1|UniProtKB=W5MK15 W5MK15 PTHR10031:SF59 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C3, MITOCHONDRIAL transporter#PC00227;primary active transporter#PC00068;ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000010394.1|UniProtKB=W5MWI7 W5MWI7 PTHR12166:SF6 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR 1 transport#GO:0006810;establishment of localization#GO:0051234;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of secretion by cell#GO:1903532;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;positive regulation of secretion#GO:0051047;localization#GO:0051179;regulation of secretion#GO:0051046;secretion#GO:0046903;secretion by cell#GO:0032940;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;export from cell#GO:0140352 cell junction#GO:0030054;synapse#GO:0045202;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000008808.1|UniProtKB=W5MQS0 W5MQS0 PTHR13723:SF140 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 16 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000008028.1|UniProtKB=W5MMZ3 W5MMZ3 MED19 PTHR22536:SF1 LUNG CANCER METASTASIS-RELATED LCMR1 PROTEIN MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000011161.1|UniProtKB=W5MZC2 W5MZC2 PTHR12100:SF0 SEC10 EXOCYST COMPLEX COMPONENT 5 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;secretion by cell#GO:0032940;exocytosis#GO:0006887 cytoplasm#GO:0005737;exocyst#GO:0000145;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 LEPOC|Ensembl=ENSLOCG00000004142.1|UniProtKB=W5M993 W5M993 PTHR20859:SF85 INTERFERON/INTERLEUKIN RECEPTOR FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN immune receptor activity#GO:0140375;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166;cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000013456.1|UniProtKB=W5N7H9 W5N7H9 PTHR37558:SF1 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN TRICHOHYALIN LEPOC|Ensembl=ENSLOCG00000006861.1|UniProtKB=W5MIT7 W5MIT7 PTHR12015:SF213 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE-RELATED cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000002112.1|UniProtKB=W5M242 W5M242 PTHR45616:SF4 GATA-TYPE DOMAIN-CONTAINING PROTEIN OUROBOROS 1 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intermediate filament#GO:0005882;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 LEPOC|Ensembl=ENSLOCG00000007335.1|UniProtKB=W5MKH5 W5MKH5 PTHR23503:SF27 SOLUTE CARRIER FAMILY 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144 transport#GO:0006810;carbohydrate transport#GO:0008643;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cluster of actin-based cell projections#GO:0098862;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;brush border#GO:0005903 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000002100.1|UniProtKB=W5M224 W5M224 PTHR31898:SF1 TRANSMEMBRANE PROTEIN 136 TLC DOMAIN-CONTAINING PROTEIN 5 LEPOC|Ensembl=ENSLOCG00000004026.1|UniProtKB=W5M8U9 W5M8U9 PTHR12386:SF12 ATP SYNTHASE SUBUNIT ATP SYNTHASE F(0) COMPLEX SUBUNIT G, MITOCHONDRIAL-RELATED proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;cellular anatomical structure#GO:0110165;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 ATP synthase#PC00002 LEPOC|Ensembl=ENSLOCG00000014716.1|UniProtKB=W5NBY0 W5NBY0 PTHR24416:SF653 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of developmental process#GO:0050793;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of neuron differentiation#GO:0045664;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;cell surface receptor signaling pathway#GO:0007166 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020 transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000012933.1|UniProtKB=W5N5M3 W5N5M3 PTHR24214:SF32 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 5 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488;protein binding#GO:0005515 developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;heart development#GO:0007507;multicellular organismal process#GO:0032501;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cellular component organization#GO:0016043;circulatory system development#GO:0072359;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061 supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell-cell junction#GO:0005911;actomyosin#GO:0042641;Z disc#GO:0030018;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;sarcomere#GO:0030017;cell junction#GO:0030054;adherens junction#GO:0005912;cytoskeleton#GO:0005856;stress fiber#GO:0001725;actin filament#GO:0005884;I band#GO:0031674;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;myofibril#GO:0030016;actin filament bundle#GO:0032432;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 LEPOC|Ensembl=ENSLOCG00000008815.1|UniProtKB=W5MQS3 W5MQS3 PTHR48041:SF49 ABC TRANSPORTER G FAMILY MEMBER 28 BROAD SUBSTRATE SPECIFICITY ATP-BINDING CASSETTE TRANSPORTER ABCG2B ISOFORM X1-RELATED primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000005114.1|UniProtKB=W5MCQ1 W5MCQ1 PTHR24072:SF141 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817 cortical cytoskeleton organization#GO:0030865;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;cell communication#GO:0007154;regulation of biological quality#GO:0065008;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of developmental process#GO:0050793;signaling#GO:0023052;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 G-protein#PC00020;small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000014178.1|UniProtKB=W5NA07 W5NA07 PTHR14211:SF7 GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2 RIBOSOME BIOGENESIS PROTEIN NOP53 RNA binding#GO:0003723;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;organelle assembly#GO:0070925;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000006548.1|UniProtKB=W5MHQ2 W5MHQ2 PTHR23412:SF18 STEREOCILIN RELATED OTOANCORIN cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160 cellular anatomical structure#GO:0110165;cell surface#GO:0009986 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000004427.1|UniProtKB=W5MA78 W5MA78 PTHR11373:SF48 DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;purine nucleotide catabolic process#GO:0006195;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;organophosphate catabolic process#GO:0046434;response to virus#GO:0009615;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of response to stress#GO:0080134;nucleotide catabolic process#GO:0009166;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;response to external stimulus#GO:0009605;defense response#GO:0006952;defense response to virus#GO:0051607;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;nucleotide metabolic process#GO:0009117;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;cellular process#GO:0009987;regulation of response to external stimulus#GO:0032101;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 hydrolase#PC00121 LEPOC|Ensembl=ENSLOCG00000016701.1|UniProtKB=W5NJ26 W5NJ26 PTHR14030:SF4 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 sister chromatid cohesion#GO:0007062;cell communication#GO:0007154;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of chromosome organization#GO:2001251;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of mitotic metaphase/anaphase transition#GO:0030071;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;meiotic sister chromatid cohesion#GO:0051177;negative regulation of chromosome segregation#GO:0051985;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome separation#GO:1905818;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094 intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013407.1|UniProtKB=W5N7C0 W5N7C0 PTHR13199:SF13 GH03947P ATOS HOMOLOG PROTEIN A LEPOC|Ensembl=ENSLOCG00000008129.1|UniProtKB=W5MND3 W5MND3 PTHR10110:SF62 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 7 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075 transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;recycling endosome#GO:0055037;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258 LEPOC|Ensembl=ENSLOCG00000012823.1|UniProtKB=W5N569 W5N569 PTHR21545:SF14 TRANSCRIPTION FACTOR MLR1/2 LIGAND-DEPENDENT COREPRESSOR regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000017146.1|UniProtKB=W5NKN0 W5NKN0 PTHR16528:SF2 GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING PROTEIN binding#GO:0005488;transmembrane transporter binding#GO:0044325;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network transport vesicle#GO:0030140;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 LEPOC|Ensembl=ENSLOCG00000000697.1|UniProtKB=W5LXB4 W5LXB4 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune response#GO:0006955;immune system process#GO:0002376 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007968.1|UniProtKB=W5MMS7 W5MMS7 PTHR23226:SF160 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN ROTUND RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000009666.1|UniProtKB=W5MTV6 W5MTV6 PTHR23506:SF30 GH10249P SYNAPTIC VESICULAR AMINE TRANSPORTER sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;solute:sodium symporter activity#GO:0015370;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;localization#GO:0051179;cellular localization#GO:0051641;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234 secretory vesicle#GO:0099503;presynapse#GO:0098793;neuron projection#GO:0043005;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;axon terminus#GO:0043679;organelle membrane#GO:0031090;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;neuron projection terminus#GO:0044306;distal axon#GO:0150034;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258;transporter#PC00227 5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410;CCKR signaling map#P06959>VMAT2#G07295;Dopamine receptor mediated signaling pathway#P05912>VAT2#P05960;Nicotine pharmacodynamics pathway#P06587>SLC18A2#P06604;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424;CCKR signaling map#P06959>VMAT2#P07137;CCKR signaling map#P06959>VMAT2#G07002;Adrenaline and noradrenaline biosynthesis#P00001>VAT2#P00070;Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071 LEPOC|Ensembl=ENSLOCG00000002985.1|UniProtKB=W5M557 W5M557 PTHR15326:SF7 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC SPERMATOGENESIS-ASSOCIATED PROTEIN 2-LIKE PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 LEPOC|Ensembl=ENSLOCG00000011131.1|UniProtKB=W5MZ66 W5MZ66 PTHR15885:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 174 COILED-COIL DOMAIN-CONTAINING PROTEIN 174 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015975.1|UniProtKB=W5NGB5 W5NGB5 PTHR11814:SF279 SULFATE TRANSPORTER PRESTIN carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108 organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;chloride transport#GO:0006821;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;dicarboxylic acid transport#GO:0006835;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009204.1|UniProtKB=W5MS77 W5MS77 PTHR46780:SF4 PROTEIN EVA-1 PROTEIN EVA-1 HOMOLOG C heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 LEPOC|Ensembl=ENSLOCG00000001042.1|UniProtKB=W5LYG4 W5LYG4 PTHR46262:SF1 FORKHEAD BOX PROTEIN BINIOU FORKHEAD BOX PROTEIN F1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 developmental process#GO:0032502;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000004309.1|UniProtKB=W5M9T8 W5M9T8 PTHR23192:SF13 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 1 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000011614.1|UniProtKB=W5N0W7 W5N0W7 PTHR31606:SF4 WW DOMAIN BINDING PROTEIN 2, ISOFORM E WW DOMAIN-BINDING PROTEIN 2 transcription coactivator activity#GO:0003713;chromatin DNA binding#GO:0031490;transcription coregulator activity#GO:0003712;DNA binding#GO:0003677;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676 positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014112.1|UniProtKB=W5N9S7 W5N9S7 PTHR48190:SF2 PROGRAMMED CELL DEATH PROTEIN 7 PROGRAMMED CELL DEATH PROTEIN 7 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 LEPOC|Ensembl=ENSLOCG00000001643.1|UniProtKB=W5M0I4 W5M0I4 PTHR13144:SF0 TEX261 PROTEIN PROTEIN TEX261 cargo receptor activity#GO:0038024 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;COPII-coated ER to Golgi transport vesicle#GO:0030134 LEPOC|Ensembl=ENSLOCG00000004425.1|UniProtKB=W5MA88 W5MA88 PTHR13140:SF879 MYOSIN UNCONVENTIONAL MYOSIN-IB microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based movement#GO:0030048;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;transport#GO:0006810;actin filament-based process#GO:0030029 cytoskeleton#GO:0005856;apical part of cell#GO:0045177;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;brush border#GO:0005903;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;microvillus#GO:0005902;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000014356.1|UniProtKB=W5NAL6 W5NAL6 PTHR23043:SF34 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA HYPOXIA INDUCIBLE FACTOR 1 SUBUNIT ALPHA, LIKE ISOFORM X1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hypoxia#GO:0071456;response to abiotic stimulus#GO:0009628;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;cellular homeostasis#GO:0019725;regulation of gene expression#GO:0010468;response to hypoxia#GO:0001666;intracellular chemical homeostasis#GO:0055082;regulation of biosynthetic process#GO:0009889;chemical homeostasis#GO:0048878 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000007705.1|UniProtKB=W5MLV0 W5MLV0 PTHR45677:SF11 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 2 carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 LEPOC|Ensembl=ENSLOCG00000003942.1|UniProtKB=W5M8J8 W5M8J8 PTHR12241:SF154 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL11 catalytic activity#GO:0003824;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157 LEPOC|Ensembl=ENSLOCG00000003714.1|UniProtKB=W5M7R8 W5M7R8 PTHR10804:SF11 PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P PROLIFERATION-ASSOCIATED PROTEIN 2G4 protease#PC00190 LEPOC|Ensembl=ENSLOCG00000004554.1|UniProtKB=W5MAP8 W5MAP8 PTHR22906:SF52 PROPERDIN ADHESION G PROTEIN-COUPLED RECEPTOR B1 LEPOC|Ensembl=ENSLOCG00000012373.1|UniProtKB=W5N3M5 W5N3M5 PTHR11956:SF5 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 aminoacyl-tRNA synthetase#PC00047 LEPOC|Ensembl=ENSLOCG00000017058.1|UniProtKB=W5NKB9 W5NKB9 PTHR46532:SF17 MALE FERTILITY FACTOR KL5 DYNEIN HEAVY CHAIN TAIL DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000014308.1|UniProtKB=W5NAF9 W5NAF9 PTHR12411:SF1044 CYSTEINE PROTEASE FAMILY C1-RELATED PRO-CATHEPSIN H peptidase activator activity#GO:0016504;enzyme activator activity#GO:0008047;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;molecular function regulator activity#GO:0098772;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;peptidase regulator activity#GO:0061134;molecular function activator activity#GO:0140677;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;adaptive immune response#GO:0002250;immune response#GO:0006955;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;protein metabolic process#GO:0019538;immune system process#GO:0002376;proteolysis#GO:0006508;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;zymogen activation#GO:0031638 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 LEPOC|Ensembl=ENSLOCG00000005576.1|UniProtKB=W5MEC9 W5MEC9 PTHR24095:SF126 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 LEPOC|Ensembl=ENSLOCG00000015857.1|UniProtKB=W5NFW3 W5NFW3 PTHR11769:SF20 HYALURONIDASE HYALURONIDASE PH-20 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosaminoglycan catabolic process#GO:0006027;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229 glycosidase#PC00110 LEPOC|Ensembl=ENSLOCG00000010422.1|UniProtKB=W5MWM5 W5MWM5 PTHR44329:SF9 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cell communication#GO:0007154;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;response to other organism#GO:0051707;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000003262.1|UniProtKB=W5M649 W5M649 PTHR12959:SF11 GPI TRANSAMIDASE COMPONENT PIG-T-RELATED GPI-ANCHOR TRANSAMIDASE COMPONENT PIGT macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;GPI anchored protein biosynthesis#GO:0180046;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;peptidase complex#GO:1905368;cytoplasm#GO:0005737;caspase complex#GO:0008303;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012730.1|UniProtKB=W5N4V3 W5N4V3 PTHR47981:SF22 RAB FAMILY RAS-RELATED PROTEIN RAB-7B hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;organelle assembly#GO:0070925;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;cellular component organization#GO:0016043;endocytosis#GO:0006897;vesicle fusion#GO:0006906;phagolysosome assembly#GO:0001845;intracellular transport#GO:0046907;phagocytosis#GO:0006909;vacuolar transport#GO:0007034;transport#GO:0006810;lytic vacuole organization#GO:0080171;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle organization#GO:0016050;cellular component biogenesis#GO:0044085;membrane fusion#GO:0061025;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174 intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;late endosome#GO:0005770;cytoplasm#GO:0005737;vacuole#GO:0005773;lytic vacuole#GO:0000323 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000017261.1|UniProtKB=W5NL40 W5NL40 PTHR48134:SF2 GLYCOPROTEIN 96-92-RELATED-RELATED TITIN-LIKE LEPOC|Ensembl=ENSLOCG00000000685.1|UniProtKB=W5LX98 W5LX98 PTHR23198:SF26 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN NUP96 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000009685.1|UniProtKB=W5MTW6 W5MTW6 PTHR33198:SF26 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000009982.1|UniProtKB=W5MUZ7 W5MUZ7 PTHR47410:SF1 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;pattern recognition receptor activity#GO:0038187 innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;response to virus#GO:0009615;intracellular signal transduction#GO:0035556;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;canonical NF-kappaB signal transduction#GO:0007249;biological regulation#GO:0065007;response to other organism#GO:0051707;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of gene expression#GO:0010628;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;regulation of gene expression#GO:0010468;toll-like receptor signaling pathway#GO:0002224;defense response to virus#GO:0051607;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;positive regulation of multicellular organismal process#GO:0051240;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;positive regulation of immune system process#GO:0002684;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;intracellular signaling cassette#GO:0141124;regulation of multicellular organismal process#GO:0051239;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 LEPOC|Ensembl=ENSLOCG00000016408.1|UniProtKB=W5NI03 W5NI03 PTHR47007:SF1 SUSHI DOMAIN-CONTAINING PROTEIN 4 SUSHI DOMAIN-CONTAINING PROTEIN 4 LEPOC|Ensembl=ENSLOCG00000018312.1|UniProtKB=W5NP54 W5NP54 PTHR45617:SF94 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 1 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013008.1|UniProtKB=W5N5W4 W5N5W4 PTHR11949:SF6 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 4 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000015502.1|UniProtKB=W5NEM1 W5NEM1 PTHR43804:SF3 LD18447P PEPTIDE CHAIN RELEASE FACTOR 1-LIKE, MITOCHONDRIAL translational termination#GO:0006415;translation#GO:0006412;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;protein-containing complex disassembly#GO:0032984;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 translation factor#PC00223;translational protein#PC00263;translation release factor#PC00225 LEPOC|Ensembl=ENSLOCG00000006498.1|UniProtKB=W5MHJ0 W5MHJ0 PTHR24411:SF26 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR TRANSCRIPTION FACTOR NF-E2 45 KDA SUBUNIT sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 LEPOC|Ensembl=ENSLOCG00000015690.1|UniProtKB=W5NFB0 W5NFB0 PTHR24012:SF699 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 2 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000015518.1|UniProtKB=W5NEN9 W5NEN9 PTHR11783:SF55 SULFOTRANSFERASE SULT SULFOTRANSFERASE 6B1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000001823.1|UniProtKB=W5M154 W5M154 PTHR14392:SF3 NIBAN FAMILY MEMBER PROTEIN NIBAN 1 LEPOC|Ensembl=ENSLOCG00000010952.1|UniProtKB=W5MYI3 W5MYI3 PTHR45689:SF8 I[[H]] CHANNEL, ISOFORM E POTASSIUM_SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 2 ISOFORM X1 metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;dendritic tree#GO:0097447;axon#GO:0030424;dendrite#GO:0030425;transmembrane transporter complex#GO:1902495 transporter#PC00227;ion channel#PC00133 LEPOC|Ensembl=ENSLOCG00000016791.1|UniProtKB=W5NJF0 W5NJF0 PTHR24095:SF110 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE 2-LIKE, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;organophosphate biosynthetic process#GO:0090407;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 LEPOC|Ensembl=ENSLOCG00000012125.1|UniProtKB=W5N2R2 W5N2R2 PTHR43684:SF17 FAMILY NOT NAMED ENOYL-COA DELTA ISOMERASE 2 catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329 intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;mitochondrion#GO:0005739;microbody#GO:0042579 LEPOC|Ensembl=ENSLOCG00000004837.1|UniProtKB=W5MBT3 W5MBT3 PTHR45615:SF13 MYOSIN HEAVY CHAIN, NON-MUSCLE UNCONVENTIONAL MYOSIN-XVIIIA macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 LEPOC|Ensembl=ENSLOCG00000001771.1|UniProtKB=W5M0Y7 W5M0Y7 PTHR12483:SF8 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS PROTEIN SLC31A2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator activity#GO:0098772;monoatomic ion transmembrane transporter activity#GO:0015075;transporter regulator activity#GO:0141108;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of monoatomic ion transport#GO:0043269;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;regulation of monoatomic cation transmembrane transport#GO:1904062;transport#GO:0006810;establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;copper ion transmembrane transport#GO:0035434;metal ion transport#GO:0030001;transition metal ion transport#GO:0000041;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000007453.1|UniProtKB=W5MKY5 W5MKY5 PTHR45897:SF5 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH AFFINITY CHOLINE TRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 localization#GO:0051179;establishment of localization#GO:0051234;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nitrogen compound transport#GO:0071705;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011499.1|UniProtKB=W5N0H9 W5N0H9 PTHR10799:SF541 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 2 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 DNA helicase#PC00011;DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000010573.1|UniProtKB=W5MX45 W5MX45 PTHR36871:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 190 COILED-COIL DOMAIN-CONTAINING PROTEIN 190 LEPOC|Ensembl=ENSLOCG00000003458.1|UniProtKB=W5M6T7 W5M6T7 PTHR35349:SF4 DYNACTIN-ASSOCIATED PROTEIN CUPIN SUPERFAMILY MEMBER 1A-RELATED microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 LEPOC|Ensembl=ENSLOCG00000016466.1|UniProtKB=W5NI82 W5NI82 PTHR23226:SF458 ZINC FINGER AND SCAN DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000000174.1|UniProtKB=W5LVN8 W5LVN8 PTHR35663:SF3 TESTIS DEVELOPMENT-RELATED PROTEIN-RELATED GENE, 30191-RELATED LEPOC|Ensembl=ENSLOCG00000003826.1|UniProtKB=W5M854 W5M854 PTHR31968:SF4 SERINE/ARGININE-RELATED PROTEIN 53 SERINE_ARGININE-RELATED PROTEIN 53 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000000261.1|UniProtKB=W5LVX9 W5LVX9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000010776.1|UniProtKB=W5MXU4 W5MXU4 PTHR45619:SF44 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT BETA ISOFORM hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cell cycle#GO:0007049;cellular process#GO:0009987;mitotic cell cycle#GO:0000278 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 p53 pathway feedback loops 2#P04398>PP2A-C#P04659;FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643;p53 pathway#P00059>PP2A#P04630;EGF receptor signaling pathway#P00018>PP2A#P00547 LEPOC|Ensembl=ENSLOCG00000002040.1|UniProtKB=W5M1V6 W5M1V6 PTHR13229:SF2 PROTEIN KISH-A PROTEIN KISH-A transport#GO:0006810;protein transport#GO:0015031;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;protein secretion#GO:0009306;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;export from cell#GO:0140352 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000017530.1|UniProtKB=W5NLX6 W5NLX6 PTHR46486:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000015594.1|UniProtKB=W5NEZ2 W5NEZ2 PTHR11036:SF16 SEMAPHORIN SEMAPHORIN-4C molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488 anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;system development#GO:0048731;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;taxis#GO:0042330;response to chemical#GO:0042221;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;presynapse#GO:0098793 membrane-bound signaling molecule#PC00152 LEPOC|Ensembl=ENSLOCG00000010999.1|UniProtKB=W5MYN2 W5MYN2 PTHR24340:SF37 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN SLOU sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000013163.1|UniProtKB=W5N6F8 W5N6F8 PTHR23348:SF42 PERIAXIN/AHNAK PERIAXIN system development#GO:0048731;plasma membrane organization#GO:0007009;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;peripheral nervous system development#GO:0007422;cellular component organization#GO:0016043;gliogenesis#GO:0042063;myelination#GO:0042552;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of RNA splicing#GO:0043484;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;membrane organization#GO:0061024;nervous system development#GO:0007399;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000012817.1|UniProtKB=W5N565 W5N565 PTHR15535:SF15 TRANSMEMBRANE PROTEIN 2-RELATED CELL MIGRATION-INDUCING AND HYALURONAN-BINDING PROTEIN hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;glycosaminoglycan catabolic process#GO:0006027;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;glycosaminoglycan metabolic process#GO:0030203;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000001054.1|UniProtKB=W5LYH9 W5LYH9 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune response#GO:0006955;immune system process#GO:0002376;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000007912.1|UniProtKB=W5MMK1 W5MMK1 PTHR10654:SF20 CAS SCAFFOLDING PROTEIN ENHANCER OF FILAMENTATION 1 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell migration#GO:0016477;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 LEPOC|Ensembl=ENSLOCG00000013126.1|UniProtKB=W5N6A9 W5N6A9 PTHR13019:SF9 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG B secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;protein transport#GO:0015031;protein secretion#GO:0009306;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;macromolecule localization#GO:0033036 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 LEPOC|Ensembl=ENSLOCG00000014953.1|UniProtKB=W5NCS2 W5NCS2 PTHR10075:SF124 BASIGIN RELATED NEOGENIN cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000011735.1|UniProtKB=W5N1B6 W5N1B6 PTHR23415:SF48 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 2 molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle phase transition#GO:0044772;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;mitotic cell cycle process#GO:1903047 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013557.1|UniProtKB=W5N7V6 W5N7V6 PTHR24404:SF23 ZINC FINGER PROTEIN ZINC FINGER PROTEIN AIOLOS DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000007022.1|UniProtKB=W5MJE4 W5MJE4 PTHR21595:SF2 PATRONIN CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 3 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 negative regulation of cellular process#GO:0048523;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;regulation of protein depolymerization#GO:1901879;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of protein depolymerization#GO:1901880;regulation of microtubule-based process#GO:0032886;supramolecular fiber organization#GO:0097435;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;microtubule cytoskeleton organization#GO:0000226;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;cytoplasmic microtubule organization#GO:0031122;regulation of cellular process#GO:0050794 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 LEPOC|Ensembl=ENSLOCG00000016211.1|UniProtKB=W5NH75 W5NH75 PTHR14215:SF2 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 2 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular component organization or biogenesis#GO:0071840;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;organelle fission#GO:0048285;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 LEPOC|Ensembl=ENSLOCG00000014843.1|UniProtKB=W5NCB8 W5NCB8 PTHR18916:SF97 DYNACTIN 1-RELATED MICROTUBULE-BINDING TUBULIN-FOLDING COFACTOR B protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cell cortex#GO:0005938;microtubule end#GO:1990752;microtubule#GO:0005874;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;nucleus#GO:0005634;microtubule plus-end#GO:0035371;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000004462.1|UniProtKB=W5MAC9 W5MAC9 PTHR45872:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;signaling receptor binding#GO:0005102;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 Axon guidance mediated by semaphorins#P00007>RhoGEF#P00333;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoGEF#P00728;Cytoskeletal regulation by Rho GTPase#P00016>Rho GEFs#P00518 LEPOC|Ensembl=ENSLOCG00000010653.1|UniProtKB=W5MXE2 W5MXE2 PTHR45168:SF3 DNAJ HOMOLOG SUBFAMILY B MEMBER 2 DNAJ HOMOLOG SUBFAMILY B MEMBER 6-LIKE ISOFORM X1 chaperone#PC00072 LEPOC|Ensembl=ENSLOCG00000003533.1|UniProtKB=W5M739 W5M739 PTHR11616:SF109 SODIUM/CHLORIDE DEPENDENT TRANSPORTER INACTIVE SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT3 transport#GO:0006810;amino acid transport#GO:0006865;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 LEPOC|Ensembl=ENSLOCG00000016536.1|UniProtKB=W5NIG5 W5NIG5 PTHR12101:SF17 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 1 ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146;developmental process#GO:0032502;heart development#GO:0007507;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;cellular process#GO:0009987 apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;sarcolemma#GO:0042383;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886 LEPOC|Ensembl=ENSLOCG00000000526.1|UniProtKB=W5LWS1 W5LWS1 PTHR23266:SF420 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;antigen binding#GO:0003823 response to stimulus#GO:0050896;adaptive immune response#GO:0002250;immune response#GO:0006955;lymphocyte mediated immunity#GO:0002449;leukocyte mediated immunity#GO:0002443;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;immunoglobulin mediated immune response#GO:0016064;immune system process#GO:0002376;immune effector process#GO:0002252 defense/immunity protein#PC00090;immunoglobulin#PC00123 LEPOC|Ensembl=ENSLOCG00000008994.1|UniProtKB=W5MRE8 W5MRE8 PTHR21706:SF16 TRANSMEMBRANE PROTEIN 65 TRANSMEMBRANE PROTEIN 65 multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;heart development#GO:0007507;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;biological regulation#GO:0065007;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of system process#GO:0044057;developmental process#GO:0032502 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000005808.1|UniProtKB=W5MF54 W5MF54 PTHR10687:SF8 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 1 vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810 recycling endosome membrane#GO:0055038;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 transfer/carrier protein#PC00219 LEPOC|Ensembl=ENSLOCG00000015633.1|UniProtKB=W5NF39 W5NF39 PTHR12786:SF1 SPLICING FACTOR SF3A-RELATED SPLICING REGULATOR SDE2 RNA binding#GO:0003723;snoRNA binding#GO:0030515;binding#GO:0005488;nucleic acid binding#GO:0003676 mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA splicing factor#PC00148 LEPOC|Ensembl=ENSLOCG00000002943.1|UniProtKB=W5M519 W5M519 PTHR23101:SF98 RAB GDP/GTP EXCHANGE FACTOR VPS9 DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;cytosol#GO:0005829;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 LEPOC|Ensembl=ENSLOCG00000004061.1|UniProtKB=W5M914 W5M914 PTHR31826:SF8 NICALIN BOS COMPLEX SUBUNIT NCLN regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 LEPOC|Ensembl=ENSLOCG00000004183.1|UniProtKB=W5M9E2 W5M9E2 PTHR15651:SF7 ARMADILLO REPEAT-CONTAINING PROTEIN 8 ARMADILLO REPEAT-CONTAINING PROTEIN 8 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 LEPOC|Ensembl=ENSLOCG00000000257.1|UniProtKB=W5LVX5 W5LVX5 PTHR10903:SF112 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 small GTPase#PC00208 LEPOC|Ensembl=ENSLOCG00000013882.1|UniProtKB=W5N917 W5N917 PTHR14164:SF12 PERICENTRIOLAR MATERIAL 1-RELATED PERICENTRIOLAR MATERIAL 1 PROTEIN cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031 intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064 LEPOC|Ensembl=ENSLOCG00000017493.1|UniProtKB=W5NLT9 W5NLT9 PTHR10270:SF111 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-3 transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;head development#GO:0060322;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000004409.1|UniProtKB=W5MA58 W5MA58 PTHR12623:SF6 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 Gonadotropin-releasing hormone receptor pathway#P06664>NAB#P06801 LEPOC|Ensembl=ENSLOCG00000014591.1|UniProtKB=W5NBG1 W5NBG1 PTHR10799:SF819 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;heterochromatin formation#GO:0031507;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 LEPOC|Ensembl=ENSLOCG00000013213.1|UniProtKB=W5N6N8 W5N6N8 PTHR19229:SF234 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA1 ISOFORM X1 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transmembrane transporter activity#GO:0022857;intramembrane lipid carrier activity#GO:0140303;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;phosphatidylcholine intramembrane carrier activity#GO:0008525;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;macromolecule localization#GO:0033036 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 LEPOC|Ensembl=ENSLOCG00000011591.1|UniProtKB=W5N0T6 W5N0T6 PTHR13723:SF157 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 1 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 LEPOC|Ensembl=ENSLOCG00000018036.1|UniProtKB=W5NNC8 W5NNC8 PTHR15654:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 184 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031 ciliary plasm#GO:0097014;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000015263.1|UniProtKB=W5NDS4 W5NDS4 PTHR46780:SF5 PROTEIN EVA-1 SUEL-TYPE LECTIN DOMAIN-CONTAINING PROTEIN LEPOC|Ensembl=ENSLOCG00000003647.1|UniProtKB=W5M7I7 W5M7I7 PTHR46032:SF6 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000002020.1|UniProtKB=W5M1T2 W5M1T2 PTHR33504:SF2 NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4 PROTEIN MFI oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 LEPOC|Ensembl=ENSLOCG00000013113.1|UniProtKB=W5N695 W5N695 PTHR21325:SF45 PHOSPHOLIPASE B, PLB1 PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298 phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 cell projection membrane#GO:0031253;cluster of actin-based cell projections#GO:0098862;apical part of cell#GO:0045177;plasma membrane region#GO:0098590;brush border membrane#GO:0031526;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;apical plasma membrane#GO:0016324;membrane#GO:0016020;brush border#GO:0005903;cell periphery#GO:0071944 phospholipase#PC00186 LEPOC|Ensembl=ENSLOCG00000007081.1|UniProtKB=W5MJL3 W5MJL3 PTHR16135:SF2 REPRESSOR OF YIELD OF DENV PROTEIN SHIFTLESS ANTIVIRAL INHIBITOR OF RIBOSOMAL FRAMESHIFTING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022 immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 LEPOC|Ensembl=ENSLOCG00000001268.1|UniProtKB=W5LZ82 W5LZ82 PTHR19354:SF6 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 3-RELATED regulation of postsynapse organization#GO:0099175;regulation of neuron projection development#GO:0010975;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cell projection organization#GO:0031344;regulation of synapse organization#GO:0050807;regulation of dendritic spine morphogenesis#GO:0061001;regulation of synapse structure or activity#GO:0050803;regulation of anatomical structure morphogenesis#GO:0022603;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biological quality#GO:0065008 cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;postsynapse#GO:0098794;dendritic spine#GO:0043197;neuron projection#GO:0043005 LEPOC|Ensembl=ENSLOCG00000009316.1|UniProtKB=W5MSK9 W5MSK9 PTHR13817:SF65 TITIN FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 3A-RELATED structural protein#PC00211 LEPOC|Ensembl=ENSLOCG00000010302.1|UniProtKB=W5MW68 W5MW68 PTHR17453:SF0 SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 establishment of protein localization to endoplasmic reticulum#GO:0072599;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein targeting to ER#GO:0045047;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytoplasm#GO:0005737 transporter#PC00227;primary active transporter#PC00068 LEPOC|Ensembl=ENSLOCG00000008607.1|UniProtKB=W5MQ04 W5MQ04 PTHR11504:SF17 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;transporter complex#GO:1990351 oxidase#PC00175 LEPOC|Ensembl=ENSLOCG00000002000.1|UniProtKB=W5M1R4 W5M1R4 PTHR23409:SF20 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 cellular process#GO:0009987;metabolic process#GO:0008152;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 reductase#PC00198;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909;p53 pathway#P00059>R2#G04692;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915 LEPOC|Ensembl=ENSLOCG00000010601.1|UniProtKB=W5MX81 W5MX81 PTHR24286:SF397 CYTOCHROME P450 26 LANOSTEROL 14-ALPHA DEMETHYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491 secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 oxygenase#PC00177 LEPOC|Ensembl=ENSLOCG00000007309.1|UniProtKB=W5MKE0 W5MKE0 PTHR19944:SF86 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN peptide binding#GO:0042277;antigen binding#GO:0003823;binding#GO:0005488;protein-containing complex binding#GO:0044877 protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of cell activation#GO:0050865;regulation of leukocyte activation#GO:0002694;cellular component organization#GO:0016043;regulation of lymphocyte activation#GO:0051249;immune system process#GO:0002376;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of cell-cell adhesion#GO:0022409;cellular component biogenesis#GO:0044085;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;positive regulation of T cell activation#GO:0050870;regulation of T cell activation#GO:0050863;positive regulation of leukocyte activation#GO:0002696;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;positive regulation of cell adhesion#GO:0045785;regulation of immune system process#GO:0002682;regulation of cell-cell adhesion#GO:0022407;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;positive regulation of lymphocyte activation#GO:0051251;antigen processing and presentation#GO:0019882;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of cell activation#GO:0050867;positive regulation of response to stimulus#GO:0048584;regulation of cell adhesion#GO:0030155;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of leukocyte cell-cell adhesion#GO:1903037 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;lysosome#GO:0005764;vesicle#GO:0031982;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;membrane#GO:0016020;vesicle membrane#GO:0012506;lysosomal membrane#GO:0005765;cell periphery#GO:0071944 major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 LEPOC|Ensembl=ENSLOCG00000011112.1|UniProtKB=W5MZ45 W5MZ45 PTHR16451:SF7 MITOCHONDRIAL DYNAMICS PROTEINS 49/51 FAMILY MEMBER MAB-21-LIKE HHH_H2TH-LIKE DOMAIN-CONTAINING PROTEIN positive regulation of organelle organization#GO:0010638;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of developmental process#GO:0051094;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of mitochondrial fission#GO:0090140;regulation of developmental process#GO:0050793;positive regulation of mitochondrial fission#GO:0090141;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;positive regulation of cellular process#GO:0048522;regulation of organelle organization#GO:0033043 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020 LEPOC|Ensembl=ENSLOCG00000009644.1|UniProtKB=W5MTS8 W5MTS8 PTHR23055:SF87 CALCIUM BINDING PROTEINS NEUROCALCIN-DELTA small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;actin binding#GO:0003779;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 calmodulin-related#PC00061 LEPOC|Ensembl=ENSLOCG00000003497.1|UniProtKB=W5M6Y1 W5M6Y1 PTHR46878:SF1 FORKHEAD BOX PROTEIN M1 FORKHEAD BOX PROTEIN M1 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;regulation of DNA metabolic process#GO:0051052;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;DNA damage response#GO:0006974;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA repair#GO:0045739;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of double-strand break repair#GO:2000779;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;cellular response to stimulus#GO:0051716;positive regulation of DNA metabolic process#GO:0051054;positive regulation of double-strand break repair#GO:2000781;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 LEPOC|Ensembl=ENSLOCG00000013078.1|UniProtKB=W5N649 W5N649 PTHR42760:SF133 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxidoreductase#PC00176 LEPOC|Ensembl=ENSLOCG00000012189.1|UniProtKB=W5N2Z5 W5N2Z5 PTHR24027:SF91 CADHERIN-23 CADHERIN-7 binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;beta-catenin binding#GO:0008013 cellular component assembly#GO:0022607;cell migration#GO:0016477;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;cell motility#GO:0048870;cell morphogenesis#GO:0000902;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell adhesion#GO:0007155 extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;anchoring junction#GO:0070161;membrane protein complex#GO:0098796;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 LEPOC|Ensembl=ENSLOCG00000005484.1|UniProtKB=W5ME48 W5ME48 PTHR10574:SF448 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-5 extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 LEPOC|Ensembl=ENSLOCG00000014544.1|UniProtKB=W5NB98 W5NB98 PTHR24034:SF194 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 4 ISOFORM X1 protein binding#GO:0005515;growth factor binding#GO:0019838;cytokine binding#GO:0019955;binding#GO:0005488;transforming growth factor beta binding#GO:0050431 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 LEPOC|Ensembl=ENSLOCG00000003983.1|UniProtKB=W5M8P2 W5M8P2 PTHR14715:SF2 FAM124 DOMAIN-CONTAINING PROTEIN-RELATED PROTEIN FAM124B intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 LEPOC|Ensembl=ENSLOCG00000016016.1|UniProtKB=W5NGH0 W5NGH0 PTHR10218:SF359 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-1 molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;G protein-coupled receptor binding#GO:0001664;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;signaling receptor binding#GO:0005102 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234 G-protein#PC00020;heterotrimeric G-protein#PC00117 PI3 kinase pathway#P00048>Galpha#P01199;Enkephalin release#P05913>G-Protein (i)#P05974;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Nicotine pharmacodynamics pathway#P06587>GNAI#P06609;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Opioid prodynorphin pathway#P05916>G-protein#P06002;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proenkephalin pathway#P05915>G-protein#P05994;Gonadotropin-releasing hormone receptor pathway#P06664>gnai/o#P06773;Endogenous cannabinoid signaling#P05730>Galpha#P05751 LEPOC|Ensembl=ENSLOCG00000001761.1|UniProtKB=W5M0X5 W5M0X5 PTHR31786:SF2 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24 chromatin binding#GO:0003682;binding#GO:0005488 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229 LEPOC|Ensembl=ENSLOCG00000004686.1|UniProtKB=W5MB51 W5MB51 PTHR24051:SF6 SUSHI DOMAIN-CONTAINING PROTEIN 1 FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN-RELATED extracellular matrix glycoprotein#PC00100 LEPOC|Ensembl=ENSLOCG00000013650.1|UniProtKB=W5N871 W5N871 PTHR11987:SF29 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8F sialyltransferase activity#GO:0008373;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 transferase#PC00220;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014707.1|UniProtKB=W5NBU5 W5NBU5 PTHR24204:SF2 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;cell fate commitment#GO:0045165;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell fate specification#GO:0001708;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;neuron fate commitment#GO:0048663;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000014024.1|UniProtKB=W5N9H8 W5N9H8 PTHR23200:SF48 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000000765.1|UniProtKB=W5LXK4 W5LXK4 PTHR24343:SF593 SERINE/THREONINE KINASE SERINE_THREONINE-PROTEIN KINASE BRSK2 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;axonogenesis#GO:0007409;neuron development#GO:0048666;cell cycle process#GO:0022402;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;mitotic cell cycle process#GO:1903047;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;mitotic cell cycle phase transition#GO:0044772;system development#GO:0048731;anatomical structure development#GO:0048856;establishment of cell polarity#GO:0030010;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000013399.1|UniProtKB=W5N7A6 W5N7A6 PTHR21559:SF22 DYSTROGLYCAN-RELATED DYSTROGLYCAN 1 protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;morphogenesis of an epithelium#GO:0002009;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;system development#GO:0048731;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856 protein-containing complex#GO:0032991;plasma membrane#GO:0005886;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;cell periphery#GO:0071944;sarcolemma#GO:0042383;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;postsynapse#GO:0098794;basement membrane#GO:0005604;plasma membrane protein complex#GO:0098797;extracellular region#GO:0005576 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000000419.1|UniProtKB=W5LWE9 W5LWE9 PTHR11440:SF47 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED LYSOSOMAL PHOSPHOLIPASE A AND ACYLTRANSFERASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;A2-type glycerophospholipase activity#GO:0004623;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycerophospholipase activity#GO:0004620 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine metabolic process#GO:0046470;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 acyltransferase#PC00042;transferase#PC00220 LEPOC|Ensembl=ENSLOCG00000017656.1|UniProtKB=W5NMA2 W5NMA2 PTHR24234:SF8 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 4-LIKE G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000011895.1|UniProtKB=W5N1X0 W5N1X0 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 LEPOC|Ensembl=ENSLOCG00000009067.1|UniProtKB=W5MRP0 W5MRP0 PTHR13214:SF1 ZINC FINGER PROTEIN 330 ZINC FINGER PROTEIN 330 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 LEPOC|Ensembl=ENSLOCG00000011262.1|UniProtKB=W5MZN3 W5MZN3 PTHR21624:SF1 STEROL DESATURASE-RELATED PROTEIN ALKYLGLYCEROL MONOOXYGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 LEPOC|Ensembl=ENSLOCG00000005142.1|UniProtKB=W5MCT6 W5MCT6 PTHR11256:SF10 BCL-2 RELATED BCL-2-RELATED PROTEIN A1 channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 positive regulation of programmed cell death#GO:0043068;release of cytochrome c from mitochondria#GO:0001836;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;signaling#GO:0023052;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;organelle fusion#GO:0048284;apoptotic mitochondrial changes#GO:0008637;mitochondrion organization#GO:0007005;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;signal transduction#GO:0007165;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;programmed cell death#GO:0012501;mitochondrial fusion#GO:0008053;cellular response to stimulus#GO:0051716;cell death#GO:0008219;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 Apoptosis signaling pathway#P00006>A1#P00283 LEPOC|Ensembl=ENSLOCG00000012681.1|UniProtKB=W5N4P3 W5N4P3 PTHR31508:SF2 PROTEIN PITCHFORK CILIARY MICROTUBULE-ASSOCIATED PROTEIN 3 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 regulation of biological process#GO:0050789;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cilium#GO:0005929;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 LEPOC|Ensembl=ENSLOCG00000015107.1|UniProtKB=W5NDA2 W5NDA2 PTHR12582:SF5 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5D molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 LEPOC|Ensembl=ENSLOCG00000011994.1|UniProtKB=W5N292 W5N292 PTHR13809:SF25 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-2 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;side of membrane#GO:0098552;catalytic complex#GO:1902494;cytoplasmic side of membrane#GO:0098562;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 heterotrimeric G-protein#PC00117 Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Nicotine pharmacodynamics pathway#P06587>GNG#P06590;CCKR signaling map#P06959>Gbeta/gamma#P07197;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Opioid proenkephalin pathway#P05915>G-protein#P05994;Gonadotropin-releasing hormone receptor pathway#P06664>Ggamma#P06754;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 LEPOC|Ensembl=ENSLOCG00000004664.1|UniProtKB=W5MB29 W5MB29 PTHR11785:SF517 AMINO ACID TRANSPORTER SI:DKEYP-120H9.1 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;basic amino acid transmembrane transporter activity#GO:0015174 amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000017074.1|UniProtKB=W5NKE6 W5NKE6 PTHR23406:SF17 MALIC ENZYME-RELATED NADP-DEPENDENT MALIC ENZYME oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 Pyruvate metabolism#P02772>Malic enzyme#P03136 LEPOC|Ensembl=ENSLOCG00000007281.1|UniProtKB=W5MKB1 W5MKB1 PTHR45915:SF5 TRANSCRIPTION INTERMEDIARY FACTOR BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;transcription regulator activity#GO:0140110;chromatin-protein adaptor activity#GO:0140463 cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 ISWI-type complex#GO:0031010;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nuclear protein-containing complex#GO:0140513;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 LEPOC|Ensembl=ENSLOCG00000007329.1|UniProtKB=W5MKH4 W5MKH4 PTHR10913:SF83 FOLLISTATIN-RELATED AGRIN central nervous system development#GO:0007417;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 LEPOC|Ensembl=ENSLOCG00000016373.1|UniProtKB=W5NHV5 W5NHV5 PTHR10390:SF31 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 visual system development#GO:0150063;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;eye development#GO:0001654;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;head development#GO:0060322;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;sensory system development#GO:0048880;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;sensory organ development#GO:0007423 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000007106.1|UniProtKB=W5MJP4 W5MJP4 PTHR45970:SF4 AGAP004664-PA HOMEOBOX PROTEIN HOX-D9 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 embryo development#GO:0009790;animal organ development#GO:0048513;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;skeletal system development#GO:0001501;animal gross anatomical part developmental process#GO:0160108;chordate embryonic development#GO:0043009;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;skeletal system morphogenesis#GO:0048705;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of macromolecule metabolic process#GO:0060255;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;embryonic organ development#GO:0048568;embryo development ending in birth or egg hatching#GO:0009792;pattern specification process#GO:0007389 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000002193.1|UniProtKB=W5M2G7 W5M2G7 PTHR13886:SF3 JNK/SAPK-ASSOCIATED PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 3 MAP kinase scaffold activity#GO:0005078;structural molecule activity#GO:0005198;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159;protein complex scaffold activity#GO:0140378;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000008454.1|UniProtKB=W5MPH7 W5MPH7 PTHR23276:SF2 PROTEIN PRRC1 PROTEIN PRRC1 protein binding#GO:0005515;binding#GO:0005488;protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237 anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000013358.1|UniProtKB=W5N757 W5N757 PTHR10562:SF152 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 2 protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 p53 pathway#P00059>Sumo-1 ligase#P04635 LEPOC|Ensembl=ENSLOCG00000015031.1|UniProtKB=W5NCZ2 W5NCZ2 PTHR24388:SF109 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 221-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 LEPOC|Ensembl=ENSLOCG00000007360.1|UniProtKB=W5MKK9 W5MKK9 PTHR16247:SF0 RIKEN CDNA 9430015G10 GENE RIKEN CDNA 9430015G10 GENE LEPOC|Ensembl=ENSLOCG00000009425.1|UniProtKB=W5MSZ3 W5MSZ3 PTHR12958:SF5 FRIEND OF GATA2-RELATED ZINC FINGER PROTEIN ZFPM2 binding#GO:0005488;transcription regulator activity#GO:0140110;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;heart development#GO:0007507;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;circulatory system development#GO:0072359;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 LEPOC|Ensembl=ENSLOCG00000017039.1|UniProtKB=W5NKA2 W5NKA2 PTHR15036:SF93 PIKACHURIN-LIKE PROTEIN PROTEIN EYES SHUT HOMOLOG multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cell junction#GO:0030054;basement membrane#GO:0005604;cell periphery#GO:0071944;external encapsulating structure#GO:0030312;membrane#GO:0016020;extracellular matrix#GO:0031012;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000006654.1|UniProtKB=W5MI23 W5MI23 PTHR31938:SF4 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000006910.1|UniProtKB=W5MIZ8 W5MIZ8 PTHR20974:SF2 UPF0585 PROTEIN CG18661 METHYLTRANSFERASE-LIKE 26 LEPOC|Ensembl=ENSLOCG00000003186.1|UniProtKB=W5M5W2 W5M5W2 PTHR23349:SF59 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST PANCREAS TRANSCRIPTION FACTOR 1 SUBUNIT ALPHA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000012292.1|UniProtKB=W5N3B3 W5N3B3 PTHR12632:SF122 TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT ALPHA DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 LEPOC|Ensembl=ENSLOCG00000005478.1|UniProtKB=W5ME17 W5ME17 PTHR31386:SF2 UNCHARACTERIZED PROTEIN KIAA2013 RIKEN CDNA 2510039O18 GENE LIKE LEPOC|Ensembl=ENSLOCG00000018275.1|UniProtKB=W5NP17 W5NP17 PTHR19290:SF161 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED BHLH TRANSCRIPTION FACTOR 3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;sensory organ development#GO:0007423;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell projection organization#GO:0030030;central nervous system development#GO:0007417;forebrain development#GO:0030900;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;animal organ development#GO:0048513;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;head development#GO:0060322;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 LEPOC|Ensembl=ENSLOCG00000003228.1|UniProtKB=W5M602 W5M602 PTHR22923:SF69 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 2 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000005804.1|UniProtKB=W5MF57 W5MF57 PTHR11819:SF128 SOLUTE CARRIER FAMILY 5 SODIUM_MANNOSE COTRANSPORTER SLC5A10 active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;sugar transmembrane transporter activity#GO:0051119;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011610.1|UniProtKB=W5N0W1 W5N0W1 PTHR22839:SF0 THO COMPLEX SUBUNIT 3 THO3 THO COMPLEX SUBUNIT 3 mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleocytoplasmic transport#GO:0006913;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription export complex#GO:0000346;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;nucleus#GO:0005634 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000006890.1|UniProtKB=W5MIX6 W5MIX6 PTHR24085:SF5 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR ALPHA transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor binding#GO:0016922;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629 cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cellular response to peptide hormone stimulus#GO:0071375;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to hormone#GO:0009725;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C4 zinc finger nuclear receptor#PC00169;DNA-binding transcription factor#PC00218 LEPOC|Ensembl=ENSLOCG00000010294.1|UniProtKB=W5MW49 W5MW49 PTHR23113:SF249 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 LEPOC|Ensembl=ENSLOCG00000000113.1|UniProtKB=W5LVG8 W5LVG8 PTHR11505:SF204 L1 TRANSPOSABLE ELEMENT-RELATED L1 TRANSPOSABLE ELEMENT RRM DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 LEPOC|Ensembl=ENSLOCG00000004512.1|UniProtKB=W5MAJ3 W5MAJ3 PTHR44468:SF3 COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR-RELATED COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609;homotypic cell-cell adhesion#GO:0034109 cellular anatomical structure#GO:0110165;basal part of cell#GO:0045178;intercalated disc#GO:0014704;anchoring junction#GO:0070161;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;cell-cell junction#GO:0005911;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;cell-cell contact zone#GO:0044291;tight junction#GO:0070160;cell junction#GO:0030054;apical junction complex#GO:0043296 LEPOC|Ensembl=ENSLOCG00000005943.1|UniProtKB=W5MFM0 W5MFM0 PTHR46292:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 102A COILED-COIL DOMAIN-CONTAINING PROTEIN 102A LEPOC|Ensembl=ENSLOCG00000017449.1|UniProtKB=W5NLP5 W5NLP5 PTHR26451:SF860 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ODORANT RECEPTOR-RELATED binding#GO:0005488;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;sensory perception of smell#GO:0007608;detection of chemical stimulus#GO:0009593;detection of stimulus#GO:0051606;detection of stimulus involved in sensory perception#GO:0050906;system process#GO:0003008;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus involved in sensory perception#GO:0050907 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000003419.1|UniProtKB=W5M6R2 W5M6R2 PTHR24049:SF41 CRUMBS FAMILY MEMBER ATTRACTIN cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 LEPOC|Ensembl=ENSLOCG00000015451.1|UniProtKB=W5NEG1 W5NEG1 PTHR24343:SF350 SERINE/THREONINE KINASE NUAK FAMILY SNF1-LIKE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 LEPOC|Ensembl=ENSLOCG00000011940.1|UniProtKB=W5N221 W5N221 PTHR24070:SF174 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-A ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular response to stimulus#GO:0051716;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;Ras protein signal transduction#GO:0007265;regulation of secretion#GO:0051046;cell communication#GO:0007154;regulation of secretion by cell#GO:1903530;intracellular signal transduction#GO:0035556;regulation of exocytosis#GO:0017157 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 Ras Pathway#P04393>Ral#P04550 LEPOC|Ensembl=ENSLOCG00000003038.1|UniProtKB=W5M5B3 W5M5B3 PTHR24061:SF418 CALCIUM-SENSING RECEPTOR-RELATED C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 LEPOC|Ensembl=ENSLOCG00000008489.1|UniProtKB=W5MPM4 W5MPM4 PTHR16171:SF13 DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED BASIC IMMUNOGLOBULIN-LIKE VARIABLE MOTIF-CONTAINING PROTEIN hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleotide-excision repair complex#GO:0000109;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000001077.1|UniProtKB=W5LYK7 W5LYK7 PTHR28584:SF1 FAMILY WITH SEQUENCE SIMILARITY 228 MEMBER A PROTEIN FAM228A LEPOC|Ensembl=ENSLOCG00000015456.1|UniProtKB=W5NEG4 W5NEG4 APPL2 PTHR46415:SF1 ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2 DCC-INTERACTING PROTEIN 13-BETA biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789 endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000016531.1|UniProtKB=W5NIF8 W5NIF8 PTHR16515:SF68 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 LEPOC|Ensembl=ENSLOCG00000015102.1|UniProtKB=W5ND80 W5ND80 PTHR10997:SF26 IMPORTIN-7, 8, 11 IMPORTIN-8 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;cellular localization#GO:0051641;protein localization to organelle#GO:0033365;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504 nucleus#GO:0005634;organelle envelope#GO:0031967;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 LEPOC|Ensembl=ENSLOCG00000011627.1|UniProtKB=W5N0X9 W5N0X9 PTHR12962:SF4 CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED COLD SHOCK DOMAIN-CONTAINING PROTEIN C2 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;post-transcriptional regulation of gene expression#GO:0010608;regulation of mRNA stability#GO:0043488;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008;regulation of RNA stability#GO:0043487 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 LEPOC|Ensembl=ENSLOCG00000001261.1|UniProtKB=W5LZ67 W5LZ67 PTHR11850:SF413 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS TGFB INDUCED FACTOR HOMEOBOX 2 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000017980.1|UniProtKB=W5NN72 W5NN72 PTHR24241:SF145 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000009757.1|UniProtKB=W5MU66 W5MU66 PTHR46348:SF1 DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 1 DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 1 binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929 LEPOC|Ensembl=ENSLOCG00000016048.1|UniProtKB=W5NGL0 W5NGL0 PTHR31878:SF0 CHEMOKINE-LIKE PROTEIN TAFA-5-RELATED CHEMOKINE-LIKE PROTEIN TAFA-5 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 chemokine#PC00074;cytokine#PC00083 LEPOC|Ensembl=ENSLOCG00000008191.1|UniProtKB=W5MNI3 W5MNI3 PTHR46110:SF4 HOMEOBOX PROTEIN HMX HOMEOBOX PROTEIN HMX2 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 LEPOC|Ensembl=ENSLOCG00000017310.1|UniProtKB=W5NLA6 W5NLA6 PTHR23267:SF486 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14_DELTA VARIABLE 4 immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000010771.1|UniProtKB=W5MXT4 W5MXT4 PTHR23322:SF109 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 8 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000002149.1|UniProtKB=W5M292 W5M292 PTHR23322:SF28 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 10 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 LEPOC|Ensembl=ENSLOCG00000013913.1|UniProtKB=W5N942 W5N942 PTHR47266:SF33 ENDONUCLEASE-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 LEPOC|Ensembl=ENSLOCG00000002964.1|UniProtKB=W5M535 W5M535 PTHR43398:SF1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 LEPOC|Ensembl=ENSLOCG00000014494.1|UniProtKB=W5NB31 W5NB31 PTHR46169:SF31 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A SIN3-HDAC COMPLEX-ASSOCIATED FACTOR,-LIKE-RELATED regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 LEPOC|Ensembl=ENSLOCG00000008052.1|UniProtKB=W5MN19 W5MN19 PTHR21351:SF0 BARDET-BIEDL SYNDROME PROTEIN 5 BBSOME COMPLEX MEMBER BBS5 phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phosphatidylinositol-3-phosphate binding#GO:0032266;phospholipid binding#GO:0005543;binding#GO:0005488 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intracellular membraneless organelle#GO:0043232;BBSome#GO:0034464;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 LEPOC|Ensembl=ENSLOCG00000000039.1|UniProtKB=W5LV88 W5LV88 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;serine hydrolase activity#GO:0017171 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000013692.1|UniProtKB=W5N8C8 W5N8C8 PTHR11599:SF62 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-3 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 LEPOC|Ensembl=ENSLOCG00000001582.1|UniProtKB=W5M0A6 W5M0A6 PTHR16650:SF9 C21ORF13-RELATED LEBERCILIN-LIKE PROTEIN microtubule-based transport#GO:0099111;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705 intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;cellular anatomical structure#GO:0110165;organelle#GO:0043226 LEPOC|Ensembl=ENSLOCG00000007370.1|UniProtKB=W5MKN1 W5MKN1 PTHR10589:SF51 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of chromosome organization#GO:0033044;biological regulation#GO:0065007;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 LEPOC|Ensembl=ENSLOCG00000000254.1|UniProtKB=W5LVX2 W5LVX2 PTHR23267:SF328 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED immune system process#GO:0002376;immune response#GO:0006955;response to stimulus#GO:0050896 protein-containing complex#GO:0032991 immunoglobulin#PC00123;defense/immunity protein#PC00090 LEPOC|Ensembl=ENSLOCG00000005146.1|UniProtKB=W5MCT9 W5MCT9 PTHR16518:SF4 G-PROTEIN COUPLED RECEPTOR 153, 162 G-PROTEIN COUPLED RECEPTOR 153 ISOFORM X1-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 LEPOC|Ensembl=ENSLOCG00000000751.1|UniProtKB=W5LXH6 W5LXH6 PTHR12737:SF16 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE HYDROLASE DDAH2-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;regulation of cellular process#GO:0050794;oxoacid metabolic process#GO:0043436;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121